--- a +++ b/man/data-methData.Rd @@ -0,0 +1,29 @@ +\name{methData} +\alias{methData} +\docType{data} +\title{ +DNA methylation data +} +\description{ +The data set includes methylation data for the 5000 most variable CpG sites of +the CLL samples. The data was produced with the use of either 450k or 850k +methylation arrays. +Preprocessing of raw IDAT files was made using minfi R/Bioconductor package + version 1.19.16. Intensities were normalized using the functional +normalization algorithm. CpG sites containing SNPs inside the probe body +were removed. +} +\author{Andreas Mock, Małgorzata Oleś} +\references{ +Oakes CC, Seifert M, Assenov Y, Gu L, Przekopowitz M, Ruppert AS, Wang Q, +Imbusch CD, Serva A, Koser SD, et al. DNA methylation dynamics during +B cell maturation underlie a continuum of disease phenotypes in chronic +lymphocytic leukemia. Nat Genet. 2016;48(3):253-64 +} +\usage{ +methData +} +\format{ +\code{"\linkS4class{RangedSummarizedExperiment}"} object with Features 5000 and Samples 196. +} +\keyword{datasets}