The initiation of the activity of the inactive enzyme MAP kinase by phosphorylation by a MAPKK [goid 187] [pmid 9924018] [evidence TAS]; The process that results in increased metabolic rate in tissues of an organism. It is triggered by the detection of dietary excess. This process is achieved via signalling in the sympathetic nervous system [goid 2024] [evidence IEA]; A process that results in an increase in the diameter of an artery during the norepinephrine-epinephrine response to blood pressure change [goid 2025] [evidence IEA]; Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of, within or between cells [goid 2028] [evidence IEA]; The process that inhibits the signaling function of a G-protein coupled receptor by uncoupling the receptor from its downstream G proteins [goid 2032] [pmid 15123695] [evidence IDA]; The uptake of external materials by cells, utilizing receptors to ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles [goid 6898] [pmid 15123695] [evidence IDA]; Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity [goid 7171] [pmid 10734107] [evidence TAS]; The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand [goid 7186] [pmid 9924018] [evidence TAS]; The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP [goid 7189] [evidence IEA]; Any process that initiates the activity of the inactive enzyme adenylate cyclase [goid 7190] [pmid 15123695] [evidence IDA]; A series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound [goid 7243] [pmid 10734107] [evidence TAS]; The directed movement of substances from endosomes to lysosomes [goid 8333] [pmid 9507004] [evidence TAS]; A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism [goid 9409] [evidence IEA]; Any process that activates or increases the frequency, rate or extent of bone mineralization [goid 30501] [evidence IEA]; Any homeostatic process by which an organism produces heat, thereby raising its internal temperature [goid 31649] [evidence IEA]; Any process that stops, prevents or reduces the frequency, rate or extent of growth of an organism to reach its usual body size [goid 40015] [evidence IEA]; Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade [goid 43410] [pmid 15123695] [evidence IDA]; The process by which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products [goid 45453] [evidence IEA]; Any process that activates or increases the frequency, rate or extent of transcription from the RNA polymerase II promoter [goid 45944] [evidence IEA]; Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction [goid 45986] [evidence IEA]; The process whereby a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria [goid 50873] [evidence IEA]