Interacting selectively with any nucleic acid [goid 3676] [evidence IEA]; Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks [goid 4519] [evidence IEA]; Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides [goid 4528] [evidence IEA]; Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides [goid 4551] [evidence IEA]; Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides [goid 4551] [pmid 8001561] [evidence EXP]; Interacting selectively with the insulin receptor [goid 5158] [pmid 7830796] [evidence IDA]; Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) [goid 5515] [pmid 11289049] [evidence IPI]; Interacting selectively with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator [goid 5524] [pmid 7830796] [evidence IDA]; Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3 [goid 16787] [evidence IEA]; Interacting selectively with an identical protein to form a homodimer [goid 42803] [pmid 7830796] [evidence IDA]; Interacting selectively with any metal ion [goid 46872] [evidence IEA]; Catalysis of the reaction: H2O + a nucleoside triphosphate = pyrophosphate + a nucleotide [goid 47429] [pmid 10513816] [evidence IDA]; Catalysis of the reaction: H2O + a nucleoside triphosphate = pyrophosphate + a nucleotide [goid 47429] [pmid 11159191] [evidence IDA]; Catalysis of the reaction: H2O + a nucleoside triphosphate = pyrophosphate + a nucleotide [goid 47429] [pmid 7830796] [evidence IDA]; Interacting selectively with 3'-phosphoadenosine 5'-phosphosulfate (PAPS), a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems [goid 50656] [pmid 7830796] [evidence IC ]