The directed movement of calcium (Ca) ions into, out of, within or between cells [goid 6816] [pmid 10899166] [evidence IDA]; The directed movement of calcium (Ca) ions into, out of, within or between cells [goid 6816] [evidence ISS]; The directed movement of chloride into, out of, within or between cells [goid 6821] [pmid 10899166] [evidence IDA]; A process whereby force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step. The chemo-mechanical energy conversion step is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length [goid 6939] [pmid 10899166] [evidence IEP]; A process whereby force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step. The chemo-mechanical energy conversion step is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length [goid 6939] [evidence ISS]; The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell [goid 7165] [evidence IEA]; The initiation of the activity of the inactive enzyme phospolipase C as the result of a series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand [goid 7202] [pmid 10899166] [evidence IDA]; The series of molecular signals generated as a consequence of a peptide neurotransmitter binding to a cell surface receptor [goid 7218] [pmid 10899166] [evidence TAS]; The sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation [goid 19226] [pmid 10899166] [evidence IEP]; The sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation [goid 19226] [evidence ISS]; A series of molecular signals in which a cell uses calcium ions to convert an extracellular signal into a response [goid 19722] [pmid 10899166] [evidence IDA]; A series of molecular signals in which a cell uses a water-soluble inositol phosphate to convert an extracellular signal into a response [goid 48016] [pmid 10899166] [evidence IDA]