The directed movement of calcium (Ca) ions into, out of, within or between cells [goid 6816] [evidence IEA]; Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. An action potential is a spike of membrane depolarization and repolarization that travels along the membrane of a cell [goid 1508] [pmid 9668070] [evidence TAS]; The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism [goid 6810] [pmid 9668070] [evidence TAS]; The process of binding or confining iron ions in an intracellular area such that they are separated from other components of a biological system [goid 6880] [pmid 9668070] [evidence TAS]; Any process that modulates the frequency, rate or extent of striated muscle contraction [goid 6942] [pmid 9668070] [evidence TAS]; The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell [goid 7165] [pmid 16130169] [evidence TAS]; The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood [goid 7507] [pmid 9668070] [evidence TAS]; The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work [goid 7517] [pmid 9668070] [evidence TAS]; Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process by which the heart decreases in volume in a characteristic way to propel blood through the body [goid 8016] [pmid 9668070] [evidence TAS]