The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments [goid 6309] [pmid 12082630] [evidence IMP]; The synthesis of either RNA on a template of DNA or DNA on a template of RNA [goid 6350] [evidence IEA]; Any process that modulates the frequency, rate or extent of DNA-dependent transcription [goid 6355] [evidence IEA]; Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules [goid 6364] [evidence IEA]; Any process that stops, prevents or reduces the frequency, rate or extent of protein kinase activity [goid 6469] [pmid 15582998] [evidence IMP]; A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface [goid 6915] [evidence IEA]; A process that directly activates any of the steps required for cell death by apoptosis [goid 6917] [pmid 12082630] [evidence IMP]; Upregulation of the activity of a caspase, any of a group of cysteine proteases involved in apoptosis [goid 6919] [pmid 12082630] [evidence IMP]; The process by which the cell cycle is halted during one of the normal phases (G1, S, G2, M) [goid 7050] [pmid 15582998] [evidence IMP]; The morphological and physiological alterations undergone by mitochondria during apoptosis [goid 8637] [pmid 12082630] [evidence IMP]; A preprogrammed process that occurs in an organism that is associated with the dismantling of an anatomical structure and an overall decline in metabolism. This may include the breakdown of organelles, membranes and other cellular components [goid 10149] [pmid 14966292] [evidence IMP]; Any process that modulates the rate or extent of progression from G2 phase to M phase of the mitotic cell cycle [goid 10389] [pmid 15582998] [evidence IMP]; Any process that stops, prevents or reduces the rate or extent of B cell proliferation [goid 30889] [evidence ISS]; Any process that affects the structure and integrity of a protein by altering the likelihood of its degradation or aggregation [goid 31647] [evidence ISS]; Any process that stops, prevents or reduces the frequency, rate or extent of immature T cell proliferation in the thymus [goid 33088] [evidence ISS]; Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle [goid 45786] [evidence IEA]; The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line [goid 48103] [evidence ISS]; Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine [goid 51444] [evidence ISS]; A point in the eukaryotic cell cycle where progress through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage [goid 75] [pmid 16243918] [evidence IMP]; Progression from G1 phase to S phase of the mitotic cell cycle [goid 82] [pmid 10208428] [evidence IDA]; Any process that stops, prevents or reduces the rate or extent of cell adhesion to the extracellular matrix [goid 1953] [pmid 10205165] [evidence IMP]; A process that directly activates any of the steps required for cell death by apoptosis [goid 6917] [pmid 10208428] [evidence IDA]; The process by which the cell cycle is halted during one of the normal phases (G1, S, G2, M) [goid 7050] [pmid 16243918] [evidence IMP]; Any process that stops, prevents or reduces the rate or extent of cell proliferation [goid 8285] [pmid 16243918] [evidence IMP]; A preprogrammed process that occurs in an organism that is associated with the dismantling of an anatomical structure and an overall decline in metabolism. This may include the breakdown of organelles, membranes and other cellular components [goid 10149] [pmid 14720514] [evidence IMP]; Any process that stops, prevents or reduces the frequency, rate or extent of cell growth [goid 30308] [pmid 10208428] [evidence IDA]; Any process that stops, prevents or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB [goid 32088] [pmid 10353611] [evidence IDA]; Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule [goid 42326] [pmid 8259215] [evidence IDA]; Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule [goid 42326] [pmid 10208428] [evidence IDA]; Any process that stops, prevents or reduces the frequency, rate or extent of CDK activity [goid 45736] [pmid 8259215] [evidence IDA]