The chemical reactions and pathways involving ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues [goid 1573] [pmid 16857350] [evidence IMP]; Any process that reduces the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion [goid 7042] [pmid 11722572] [evidence IMP]; The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image [goid 7601] [evidence IEA]; The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues [goid 8203] [pmid 16857350] [evidence IMP]; The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds [goid 30163] [pmid 10740217] [evidence NAS]; The chemical reactions and pathways involving glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars. Formerly known as mucopolysaccharides, they include hyaluronic acid and chondroitin, which provide lubrication in joints and form part of the matrix of cartilage. The three-dimensional structure of these molecules enables them to trap water, which forms a gel and gives glycosaminoglycans their elastic properties [goid 30203] [pmid 16857350] [evidence IMP]; Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement [goid 31987] [evidence IEA]; The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells [goid 44265] [evidence IEA]; Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein [goid 45862] [pmid 15010453] [evidence IMP]