The process by which the hormones modulates the force of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action [goid 3058] [pmid 1652300] [evidence TAS]; Any process which increases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine [goid 3099] [pmid 1652300] [evidence TAS]; The process by which endothelin modulates the force with which blood passes through the circulatory system. Endothelin is a hormone that is released by the endothelium, and it is a vasoconstrictor [goid 3100] [pmid 2649896] [evidence IDA]; The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand [goid 7169] [pmid 9492062] [evidence TAS]; Any process that increases the concentration of calcium ions in the cytosol [goid 7204] [pmid 1917960] [evidence IDA]; The initiation of the activity of the inactive enzyme protein kinase C as the result of a series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand [goid 7205] [pmid 9492062] [evidence TAS]; Any process that activates or increases the rate or extent of cell proliferation [goid 8284] [pmid 1917960] [evidence IDA]; Any process that activates or increases the frequency or rate of heart contraction [goid 10460] [pmid 2649896] [evidence IDA]; A process whereby force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the artery. Force generation involves a chemo-mechanical energy conversion step. The chemo-mechanical energy conversion step is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The artery is a vessel carrying blood away from the heart [goid 14824] [pmid 1725334] [evidence TAS]; A process whereby force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the vein. Force generation involves a chemo-mechanical energy conversion step. The chemo-mechanical energy conversion step is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The vein is a vessel carrying blood away from the capillary beds [goid 14826] [pmid 1816758] [evidence TAS]; Any series of molecular signals generated as a consequence of a cytokine or chemokine binding to a cell surface receptor [goid 19221] [pmid 12207323] [evidence IDA]; Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels [goid 19229] [evidence IEA]; A series of molecular signals in which a cell uses calcium ions to convert an extracellular signal into a response [goid 19722] [pmid 1917960] [evidence IDA]; The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding [goid 30593] [pmid 12207323] [evidence TAS]; A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor [goid 42116] [pmid 12207323] [evidence IDA]; Any process that activates or increases the frequency, rate or extent of smooth muscle contraction [goid 45987] [evidence IEA]; A series of molecular signals in which a cell uses a water-soluble inositol phosphate to convert an extracellular signal into a response [goid 48016] [pmid 1917960] [evidence IDA]; The movement of a macrophage in response to an external stimulus [goid 48246] [pmid 12207323] [evidence IDA]