The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors [goid 1913] [pmid 15811952] [evidence IDA]; A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface [goid 6915] [evidence IEA]; Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat [goid 6955] [evidence IEA]; The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules [goid 7155] [evidence IEA]; The attachment of an adhesion molecule in one cell to an identical molecule in an adjacent cell [goid 7156] [pmid 12826663] [evidence ISS]; The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell [goid 7157] [pmid 12826663] [evidence ISS]; The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult) [goid 7275] [evidence IEA]; The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis [goid 7283] [evidence IEA]; The process by which a cell in a multicellular organism interprets its surroundings [goid 8037] [pmid 15811952] [evidence IDA]; The process by which a cell in a multicellular organism interprets its surroundings [goid 8037] [pmid 12826663] [evidence ISS]; The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate [goid 30154] [evidence IEA]; The process of causing a cell to become susceptible to natural killer cell mediated cytotoxicity [goid 42271] [pmid 15811952] [evidence IDA]; The process of causing a cell to become susceptible to natural killer cell mediated cytotoxicity [goid 42271] [pmid 12826663] [evidence ISS]; Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle [goid 45786] [evidence IEA]; Any process that activates or increases the frequency, rate or extent of the regulated release of cytokines from a cell or group of cells [goid 50715] [pmid 15811952] [evidence IDA]; The expansion of a T cell population following activation by an antigenic stimulus [goid 50798] [pmid 15811952] [evidence IDA]; The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal [goid 51606] [pmid 15811952] [evidence IDA]; The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal [goid 51606] [pmid 12826663] [evidence ISS]