A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level [goid 1666] [pmid 15174142] [evidence IEP]; A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand [goid 1775] [pmid 8223854] [evidence IDA]; Any process that modulates the frequency, rate or extent of the cytokine and chemokine mediated signaling pathway [goid 1959] [pmid 16390867] [evidence ISS]; A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin [goid 2237] [pmid 15493995] [evidence ISS]; A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response [goid 2768] [pmid 11313396] [evidence IC ]; Any process that increases the concentration of calcium ions in the cytosol [goid 7204] [pmid 8223854] [evidence IDA]; Any process that increases the concentration of calcium ions in the cytosol [goid 7204] [pmid 2153173] [evidence IDA]; Any process induced by intracellular signals that directly activates any of the steps required for cell death by apoptosis [goid 8629] [pmid 11313396] [evidence NAS]; The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state [goid 16055] [pmid 16532032] [evidence NAS]; The attachment of one cell to another cell via adhesion molecules [goid 16337] [pmid 15633604] [evidence NAS]; The orderly movement of cells from one site to another, often during the development of a multicellular organism [goid 16477] [pmid 16390867] [evidence ISS]; Any process that modulates the frequency, rate or extent of epithelial cell differentiation [goid 30856] [pmid 16930538] [evidence NAS]; The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation [goid 31295] [pmid 11272271] [evidence IDA]; The directed movement of a B cell receptor into a membrane raft [goid 32597] [pmid 11313396] [evidence IDA]; The directed movement of a chemokine receptor out of a membrane raft [goid 32600] [evidence ISS]; Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta3 [goid 32913] [pmid 16930538] [evidence IMP]; Any process that activates or increases the rate or extent of activated T cell proliferation [goid 42104] [pmid 11272271] [evidence IDA]; Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule [goid 42325] [pmid 11313396] [evidence IDA]; Any process involved in the maintenance of an internal equilibrium of cholesterol within an organism or cell [goid 42632] [pmid 16390867] [evidence ISS]; Any process that activates or increases the frequency, rate or extent of MAP kinase activity [goid 43406] [pmid 12496407] [evidence IDA]; Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade [goid 43408] [pmid 11313396] [evidence IDA]; A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics [goid 43627] [pmid 10037815] [evidence IEP]; A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals [goid 45730] [pmid 8223854] [evidence IDA]