A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response [goid 2281] [pmid 2402637] [evidence ISS]; The directed movement of lipids into, out of, within or between cells. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent [goid 6869] [evidence IEA]; Process involving non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals [goid 6953] [pmid 2477488] [evidence ISS]; Process involving non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals [goid 6953] [pmid 12932360] [evidence IEP]; A defense response that is mediated by cells [goid 6968] [pmid 2402637] [evidence ISS]; The process by which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody [goid 8228] [pmid 2477488] [evidence ISS]; The process by which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody [goid 8228] [pmid 12932360] [evidence IC ]; The directed movement of lipopolysaccharides into, out of, within or between cells. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide [goid 15920] [pmid 8985160] [evidence IDA]; The series of molecular signals generated in response to detection of lipopolysaccharide [goid 31663] [pmid 8409400] [evidence IDA]; The series of molecular signals generated in response to detection of lipopolysaccharide [goid 31663] [pmid 11739189] [evidence IDA]; The series of events in which a stimulus from a molecule of bacterial origin is received and converted into a molecular signal [goid 32490] [pmid 11528597] [evidence IDA]; A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria [goid 32496] [pmid 11739189] [evidence IDA]; A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria [goid 32496] [pmid 8409400] [evidence IDA]; Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production [goid 32720] [pmid 11739189] [evidence IDA]; Any process that activates or increases the frequency, rate, or extent of interleukin-6 production [goid 32755] [pmid 8409400] [evidence IDA]; Any process that activates or increases the frequency, rate, or extent of interleukin-8 production [goid 32757] [pmid 8409400] [evidence IDA]; Any process that activates or increases the frequency, rate, or extent of tumor necrosis factor production [goid 32760] [pmid 8409400] [evidence IDA]; Any process that activates or increases the frequency, rate, or extent of tumor necrosis factor production [goid 32760] [pmid 2402637] [evidence ISS]; Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway [goid 34145] [pmid 11528597] [evidence IDA]; Any process that stimulates, induces or increases the rate of macrophage activation [goid 43032] [pmid 8409400] [evidence IDA]; Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens [goid 45087] [pmid 2477488] [evidence ISS]; Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens [goid 45087] [pmid 12932360] [evidence IC ]; Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism [goid 50829] [pmid 2402637] [evidence ISS]; Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism [goid 50830] [pmid 12932360] [evidence IC ]; Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism [goid 50830] [pmid 12932360] [evidence IEP]; Any process that increases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals [goid 60265] [evidence ISS]