Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of, within or between cells [goid 2028] [pmid 17785580] [evidence ISS]; The directed movement of charged atoms or small charged molecules into, out of, within or between cells [goid 6811] [evidence IEA]; Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell [goid 7166] [evidence ISS]; Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components [goid 10524] [pmid 9038151] [evidence IDA]; The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances [goid 19233] [evidence ISS]; Any process that activates or increases the frequency, rate or extent of bone mineralization [goid 30501] [evidence ISS]; The assembly of a bleb, a cell extension characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusions [goid 32060] [evidence ISS]; A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus [goid 33198] [pmid 9038151] [evidence IDA]; Any process that modulates the occurrence or rate of cell death by apoptosis [goid 42981] [evidence ISS]; Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade [goid 43409] [evidence ISS]; Any process that stops, prevents or reduces the frequency, rate or extent of bone resorption [goid 45779] [evidence ISS]; Any process that activates or increases the frequency, rate or extent of cytolysis [goid 45919] [evidence ISS]; The formation of a pore complex, a small opening in a membrane that allows the passage of liquids and/or gases [goid 46931] [pmid 9038151] [evidence IDA]; Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell or group of cells [goid 50718] [pmid 17036048] [evidence IDA]; Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell or group of cells [goid 50718] [pmid 18089587] [evidence IDA]; Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures [goid 51495] [evidence ISS]; Any process that modulates the frequency, rate or extent of the killing by an organism of cells in another organism [goid 51709] [pmid 17785580] [evidence NAS]; The process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential [goid 51899] [pmid 9038151] [evidence IDA]; The directed movement of charged atoms or small charged molecules into, out of, within or between cells [goid 6811] [evidence IEA]; The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells [goid 6812] [evidence IEA]; Any process that activates or increases the frequency, rate or extent of bone mineralization [goid 30501] [evidence IEA]; Any process that stops, prevents or reduces the frequency, rate or extent of bone resorption [goid 45779] [evidence IEA]; The directed movement of charged atoms or small charged molecules into, out of, within or between cells [goid 6811] [evidence IEA]