The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton) [goid 1501] [pmid 10865214] [evidence TAS]; The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure [goid 1541] [pmid 9166111] [evidence NAS]; A process that directly activates any of the steps required for cell death by apoptosis [goid 6917] [pmid 8267637] [evidence IDA]; The process by which the cell cycle is halted during one of the normal phases (G1, S, G2, M) [goid 7050] [pmid 12456957] [evidence TAS]; Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell [goid 7166] [pmid 12456957] [evidence TAS]; Any process that mediates the transfer of information from one cell to another [goid 7267] [pmid 12456957] [evidence TAS]; The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state [goid 7399] [pmid 10320815] [evidence NAS]; A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus [goid 9605] [pmid 10320815] [evidence TAS]; The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate [goid 30154] [pmid 12456957] [evidence TAS]; The process by which a myeloid precursor cell acquires specializes features of an erythrocyte [goid 30218] [pmid 1310063] [evidence NAS]; Any process that modulates the frequency, rate or extent of cell proliferation [goid 42127] [pmid 9032295] [evidence IDA]; Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule [goid 42326] [pmid 12456957] [evidence TAS]; The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin [goid 42541] [pmid 1310063] [evidence IDA]; Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma [goid 45077] [pmid 12456957] [evidence TAS]; Any process that stops, prevents or reduces the frequency, rate or extent of B cell differentiation [goid 45578] [pmid 12456957] [evidence TAS]; Any process that stops, prevents or reduces the frequency, rate or extent of macrophage differentiation [goid 45650] [pmid 12456957] [evidence TAS]; Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle [goid 45786] [pmid 12456957] [evidence TAS]; Any process that activates or increases the frequency, rate or extent of the regulated release of follicle-stimulating hormone [goid 46881] [pmid 12456957] [evidence TAS]; Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone [goid 46882] [pmid 3267209] [evidence NAS]