"""
.. _ex-res-metrics:
==================================================
Compute spatial resolution metrics in source space
==================================================
Compute peak localisation error and spatial deviation for the point-spread
functions of dSPM and MNE. Plot their distributions and difference of
distributions. This example mimics some results from :footcite:`HaukEtAl2019`,
namely Figure 3 (peak localisation error for PSFs, L2-MNE vs dSPM) and Figure 4
(spatial deviation for PSFs, L2-MNE vs dSPM).
"""
# Author: Olaf Hauk <olaf.hauk@mrc-cbu.cam.ac.uk>
#
# License: BSD-3-Clause
# Copyright the MNE-Python contributors.
# %%
import mne
from mne.datasets import sample
from mne.minimum_norm import make_inverse_resolution_matrix, resolution_metrics
print(__doc__)
data_path = sample.data_path()
subjects_dir = data_path / "subjects"
meg_path = data_path / "MEG" / "sample"
fname_fwd = meg_path / "sample_audvis-meg-eeg-oct-6-fwd.fif"
fname_cov = meg_path / "sample_audvis-cov.fif"
fname_evo = meg_path / "sample_audvis-ave.fif"
# read forward solution
forward = mne.read_forward_solution(fname_fwd)
# forward operator with fixed source orientations
mne.convert_forward_solution(forward, surf_ori=True, force_fixed=True, copy=False)
# noise covariance matrix
noise_cov = mne.read_cov(fname_cov)
# evoked data for info
evoked = mne.read_evokeds(fname_evo, 0)
# make inverse operator from forward solution
# free source orientation
inverse_operator = mne.minimum_norm.make_inverse_operator(
info=evoked.info, forward=forward, noise_cov=noise_cov, loose=0.0, depth=None
)
# regularisation parameter
snr = 3.0
lambda2 = 1.0 / snr**2
# %%
# MNE
# ---
# Compute resolution matrices, peak localisation error (PLE) for point spread
# functions (PSFs), spatial deviation (SD) for PSFs:
rm_mne = make_inverse_resolution_matrix(
forward, inverse_operator, method="MNE", lambda2=lambda2
)
ple_mne_psf = resolution_metrics(
rm_mne, inverse_operator["src"], function="psf", metric="peak_err"
)
sd_mne_psf = resolution_metrics(
rm_mne, inverse_operator["src"], function="psf", metric="sd_ext"
)
del rm_mne
# %%
# dSPM
# ----
# Do the same for dSPM:
rm_dspm = make_inverse_resolution_matrix(
forward, inverse_operator, method="dSPM", lambda2=lambda2
)
ple_dspm_psf = resolution_metrics(
rm_dspm, inverse_operator["src"], function="psf", metric="peak_err"
)
sd_dspm_psf = resolution_metrics(
rm_dspm, inverse_operator["src"], function="psf", metric="sd_ext"
)
del rm_dspm, forward
# %%
# Visualize results
# -----------------
# Visualise peak localisation error (PLE) across the whole cortex for MNE PSF:
brain_ple_mne = ple_mne_psf.plot(
"sample",
"inflated",
"lh",
subjects_dir=subjects_dir,
figure=1,
clim=dict(kind="value", lims=(0, 2, 4)),
)
brain_ple_mne.add_text(0.1, 0.9, "PLE MNE", "title", font_size=16)
# %%
# And dSPM:
brain_ple_dspm = ple_dspm_psf.plot(
"sample",
"inflated",
"lh",
subjects_dir=subjects_dir,
figure=2,
clim=dict(kind="value", lims=(0, 2, 4)),
)
brain_ple_dspm.add_text(0.1, 0.9, "PLE dSPM", "title", font_size=16)
# %%
# Subtract the two distributions and plot this difference
diff_ple = ple_mne_psf - ple_dspm_psf
brain_ple_diff = diff_ple.plot(
"sample",
"inflated",
"lh",
subjects_dir=subjects_dir,
figure=3,
clim=dict(kind="value", pos_lims=(0.0, 1.0, 2.0)),
)
brain_ple_diff.add_text(0.1, 0.9, "PLE MNE-dSPM", "title", font_size=16)
# %%
# These plots show that dSPM has generally lower peak localization error (red
# color) than MNE in deeper brain areas, but higher error (blue color) in more
# superficial areas.
#
# Next we'll visualise spatial deviation (SD) across the whole cortex for MNE
# PSF:
brain_sd_mne = sd_mne_psf.plot(
"sample",
"inflated",
"lh",
subjects_dir=subjects_dir,
figure=4,
clim=dict(kind="value", lims=(0, 2, 4)),
)
brain_sd_mne.add_text(0.1, 0.9, "SD MNE", "title", font_size=16)
# %%
# And dSPM:
brain_sd_dspm = sd_dspm_psf.plot(
"sample",
"inflated",
"lh",
subjects_dir=subjects_dir,
figure=5,
clim=dict(kind="value", lims=(0, 2, 4)),
)
brain_sd_dspm.add_text(0.1, 0.9, "SD dSPM", "title", font_size=16)
# %%
# Subtract the two distributions and plot this difference:
diff_sd = sd_mne_psf - sd_dspm_psf
brain_sd_diff = diff_sd.plot(
"sample",
"inflated",
"lh",
subjects_dir=subjects_dir,
figure=6,
clim=dict(kind="value", pos_lims=(0.0, 1.0, 2.0)),
)
brain_sd_diff.add_text(0.1, 0.9, "SD MNE-dSPM", "title", font_size=16)
# %%
# These plots show that dSPM has generally higher spatial deviation than MNE
# (blue color), i.e. worse performance to distinguish different sources.
#
# References
# ----------
# .. footbibliography::