--- a +++ b/man/shaPRS_rho.Rd @@ -0,0 +1,32 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/shaPRS.R +\name{shaPRS_rho} +\alias{shaPRS_rho} +\title{Calculate rho to be used in shaPRS_adjust()} +\usage{ +shaPRS_rho(nkl0, nk1, nk0, nl1, nl0) +} +\arguments{ +\item{nkl0}{number of controls overlapping between studies} + +\item{nk1}{number of cases in study k} + +\item{nk0}{number of controls in study k} + +\item{nl1}{number of cases in study l} + +\item{nl0}{number of controls in study l} +} +\value{ +returns real value of the approximate correlation +} +\description{ +Convenience function to estimate the correlation between two studies with overlapping controls +for more details see: +Lin et al. 'Meta-Analysis of Genome-wide Association Studies with Overlapping Subjects' (2009 +ncbi.nlm.nih.gov/pmc/articles/PMC2790578 +} +\examples{ +rho = shaPRS_rho(nkl0 = 9492,nk1 = 3810, nk0= 9492, nl1= 3765,nl0= 9492) + +}