--- a +++ b/GenomicsIntro.tex @@ -0,0 +1,50 @@ +\documentclass{article} + +\usepackage[margin = 1in]{geometry} +\usepackage{hyperref} +\hypersetup{colorlinks = TRUE, citecolor=blue} +\usepackage{amsmath} +\usepackage{amssymb} +\usepackage{graphicx} +\usepackage[export]{adjustbox} +\usepackage{natbib} +\linespread{2} +\usepackage{indentfirst} + +\begin{document} + +\section{?All models are wrong. Some models are useful. (George Box)} + +\section{Introduction to Genomics} +\subsection{What is DNA?} +% first concepts to define: DNA, gene, expression +% what genes do + +\subsection{Common Misconceptions} + +DNA does not define everything about you. +- which genes are "turned on/off" +- different upbringings and environments + + +\subsection{(Define Jargon) Genomic Variation} + +\subsection{Why study Genomic Variation?} +- Important for health and precision medicine +- Catalogs different ways in which people's genomes are healthy. +- When looking for disease-related genomic variants, we can use this information to rule out healthy variants. + +\subsection{Natural Selection} + +Thus, a variant that occurs naturally in a population likely doesn't cause disease symptoms. + +\subsection{(Define Jargon) SNPs} +Single Nucleotide Polymorphism +poly- many +morph - +Why SNP data ? + +\subsection{Data (vcf file)} + + +\end{document} \ No newline at end of file