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b/GenomicsIntro.tex |
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\documentclass{article} |
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\usepackage[margin = 1in]{geometry} |
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\usepackage{hyperref} |
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\hypersetup{colorlinks = TRUE, citecolor=blue} |
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\usepackage{amsmath} |
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\usepackage{amssymb} |
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\usepackage{graphicx} |
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\usepackage[export]{adjustbox} |
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\usepackage{natbib} |
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\linespread{2} |
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\usepackage{indentfirst} |
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\begin{document} |
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\section{?All models are wrong. Some models are useful. (George Box)} |
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\section{Introduction to Genomics} |
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\subsection{What is DNA?} |
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% first concepts to define: DNA, gene, expression |
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% what genes do |
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\subsection{Common Misconceptions} |
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DNA does not define everything about you. |
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- which genes are "turned on/off" |
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- different upbringings and environments |
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\subsection{(Define Jargon) Genomic Variation} |
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\subsection{Why study Genomic Variation?} |
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- Important for health and precision medicine |
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- Catalogs different ways in which people's genomes are healthy. |
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- When looking for disease-related genomic variants, we can use this information to rule out healthy variants. |
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\subsection{Natural Selection} |
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Thus, a variant that occurs naturally in a population likely doesn't cause disease symptoms. |
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\subsection{(Define Jargon) SNPs} |
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Single Nucleotide Polymorphism |
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poly- many |
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morph - |
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Why SNP data ? |
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\subsection{Data (vcf file)} |
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\end{document} |