--- a +++ b/man/hsstan-package.Rd @@ -0,0 +1,56 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/hsstan-package.R +\docType{package} +\name{hsstan-package} +\alias{hsstan-package} +\title{Hierarchical shrinkage Stan models for biomarker selection} +\description{ +The \strong{hsstan} package provides linear and logistic regression models +penalized with hierarchical shrinkage priors for selection of biomarkers. +Models are fitted with Stan (Carpenter et al. (2017)), which allows to +perform full Bayesian inference. +} +\details{ +The package implements the horseshoe and regularized horseshoe priors +(Piironen and Vehtari (2017)), and the projection predictive selection +approach to recover a sparse set of predictive biomarkers (Piironen, +Paasiniemi and Vehtari (2020)). + +The approach is particularly suited to selection from high-dimensional +panels of biomarkers, such as those that can be measured by MSMS or similar +technologies (Colombo, Valo, McGurnaghan et al. (2019), Colombo, McGurnaghan, +Blackbourn et al. (2020)). +} +\references{ +B. Carpenter et al. (2017), +Stan: a probabilistic programming language, +\emph{Journal of Statistical Software}, 76 (1). +\doi{10.18637/jss.v076.i01} + +J. Piironen and A. Vehtari (2017), +Sparsity information and regularization in the horseshoe and other shrinkage +priors, \emph{Electronic Journal of Statistics}, 11 (2), 5018-5051. +\doi{10.1214/17-EJS1337SI} + +J. Piironen, M. Paasiniemi and A. Vehtari (2020), +Projective inference in high-dimensional problems: prediction and feature +selection, \emph{Electronic Journal of Statistics}, 14 (1), 2155-2197. +\doi{10.1214/20-EJS1711} + +M. Colombo, E. Valo, S.J. McGurnaghan et al. (2019), +Biomarkers associated with progression of renal disease in type 1 diabetes, +\emph{Diabetologia}, 62 (9), 1616-1627. +\doi{10.1007/s00125-019-4915-0} + +M. Colombo, S.J. McGurnaghan, L.A.K. Blackbourn et al. (2020), +Comparison of serum and urinary biomarker panels with albumin creatinin +ratio in the prediction of renal function decline in type 1 diabetes, +\emph{Diabetologia}, 63 (4), 788-798. +\doi{10.1007/s00125-019-05081-8} + +M. Colombo, A. Asadi Shehni, I. Thoma et al. (2021), +Quantitative levels of serum N-glycans in type 1 diabetes and their +association with kidney disease, +\emph{Glycobiology}, 31 (5), 613-623. +\doi{10.1093/glycob/cwaa106} +}