--- a
+++ b/setup_renv.R
@@ -0,0 +1,48 @@
+# Install renv if not already installed
+if (!requireNamespace("renv", quietly = TRUE)) {
+  install.packages("renv", repos = "https://cloud.r-project.org")
+}
+
+# Initialize renv
+renv::init(force = TRUE)
+
+# Install BiocManager first
+if (!requireNamespace("BiocManager", quietly = TRUE)) {
+  install.packages("BiocManager")
+}
+
+# Install Bioconductor packages first
+BiocManager::install(c("MAST", "DESeq2", "SingleCellExperiment"))
+
+# Install CRAN packages
+renv::install(c(
+  "svDialogs",
+  "vroom",
+  "dplyr",
+  "DT",
+  "Seurat",
+  "harmony",
+  "patchwork",
+  "ggplot2",
+  "ggrepel",
+  "ggvenn",
+  "openxlsx",
+  "progress",
+  "rio",
+  "pheatmap",
+  "ggfortify",
+  "devtools",
+  "Rcpp",
+  "RcppArmadillo"
+))
+
+# Install presto from GitHub with explicit dependencies
+renv::install("immunogenomics/presto", type = "github")
+
+# Verify presto installation
+if (!requireNamespace("presto", quietly = TRUE)) {
+  stop("Failed to install presto package")
+}
+
+# Snapshot the current state
+renv::snapshot() 
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