% Generated by roxygen2: do not edit by hand

% Please edit documentation in R/rnaseq.R

\name{rnaseq_ic}

\alias{rnaseq_ic}

\title{Utility for using voom transformation with TMLE for biomarker discovery}

\usage{

rnaseq_ic(biotmle, weights = TRUE, ...)

}

\arguments{

\item{biotmle}{A \code{bioTMLE} object containing next-generation sequencing

count data in its "assays" slot.}

\item{weights}{A \code{logical} indicating whether to return quality weights

of samples in the output object.}

\item{...}{Other arguments to be passed to \code{\link[limma]{voom}} or

\code{\link[limma]{voomWithQualityWeights}} as appropriate.}

}

\value{

\code{EList} object containing voom-transformed expression measures

 of count data (actually, the mean-variance trend) in the "E" slot, to be

 passed into the biomarker TMLE procedure.

}

\description{

This function prepares next-generation sequencing data (counts) for use with

the biomarker TMLE procedure by invoking the voom transform of \code{limma}.

}