Utility for using voom transformation with TMLE for biomarker discovery

This function prepares next-generation sequencing data (counts) for use with the biomarker TMLE procedure by invoking the voom transform of limma.

rnaseq_ic(biotmle, weights = TRUE, ...)

Arguments

biotmle	A bioTMLE object containing next-generation sequencing count data in its "assays" slot.
weights	A logical indicating whether to return quality weights of samples in the output object.
...	Other arguments to be passed to voom or voomWithQualityWeights as appropriate.

Value

EList object containing voom-transformed expression measures of count data (actually, the mean-variance trend) in the "E" slot, to be passed into the biomarker TMLE procedure.