% Generated by roxygen2: do not edit by hand

% Please edit documentation in R/helper_function.R

\name{permutation_pc}

\alias{permutation_pc}

\title{Permutations to build differential network based on partial correlation analysis}

\usage{

permutation_pc(

  m,

  p,

  n_group_1,

  n_group_2,

  data_group_1,

  data_group_2,

  rho_group_1_opt,

  rho_group_2_opt

)

}

\arguments{

\item{m}{This is the number of permutations.}

\item{p}{This is the number of biomarker candidates.}

\item{n_group_1}{This is the number of subjects in group 1.}

\item{n_group_2}{This is the number of subjects in group 2.}

\item{data_group_1}{This is a \eqn{n*p} matrix containing group 1 data.}

\item{data_group_2}{This is a \eqn{n*p} matrix containing group 2 data.}

\item{rho_group_1_opt}{This is an optimal tuning parameter to obtain a sparse differential 

network for group 1.}

\item{rho_group_2_opt}{This is an optimal tuning parameter to obtain a sparse differential

network for group 2.}

}

\value{

A multi-dimensional matrix that contains the permutation result.

}

\description{

A permutation test that randomly permutes the sample labels in distinct

    biological groups for each biomolecule. The difference in paired partial correlation

    is considered statistically significant if it falls into the 2.5% tails on either end of the 

    empirical distribution curve.

}