--- a +++ b/DESCRIPTION @@ -0,0 +1,96 @@ +Package: DIscBIO +Date: 2023-11-06 +Title: A User-Friendly Pipeline for Biomarker Discovery in Single-Cell Transcriptomics +Version: 1.2.2 +Authors@R: + c( + person( + given = "Salim", + family = "Ghannoum", + role = c("aut", "cph"), + email = "salim.ghannoum@medisin.uio.no" + ), + person( + given = "Alvaro", + family = "Köhn-Luque", + role = c("aut", "ths"), + email = "alvaro.kohn-luque@medisin.uio.no" + ), + person( + given = "Waldir", + family = "Leoncio", + role = c("cre", "aut"), + email = "w.l.netto@medisin.uio.no" + ), + person( + given = "Damiano", + family = "Fantini", + role = c("ctb") + ) + ) +Description: An open, multi-algorithmic pipeline for easy, fast and efficient + analysis of cellular sub-populations and the molecular signatures that + characterize them. The pipeline consists of four successive steps: data + pre-processing, cellular clustering with pseudo-temporal ordering, defining + differential expressed genes and biomarker identification. More details on + Ghannoum et. al. (2021) <doi:10.3390/ijms22031399>. This package implements + extensions of the work published by Ghannoum et. al. (2019) + <doi:10.1101/700989>. +License: MIT + file LICENSE +Encoding: UTF-8 +Imports: methods, TSCAN, httr, mclust, statmod, igraph, + RWeka, vegan, NetIndices, png, grDevices, + RColorBrewer, ggplot2, rpart, fpc, cluster, rpart.plot, + tsne, AnnotationDbi, org.Hs.eg.db, graphics, stats, utils, impute, + withr +Depends: + R (>= 4.0), SingleCellExperiment +Suggests: + testthat, + Seurat +LazyData: true +RoxygenNote: 7.2.3 +URL: https://github.com/ocbe-uio/DIscBIO +BugReports: https://github.com/ocbe-uio/DIscBIO/issues +Collate: + 'DIscBIO-classes.R' + 'DIscBIO-generic-ClassVectoringDT.R' + 'DIscBIO-generic-ClustDiffGenes.R' + 'DIscBIO-generic-Clustexp.R' + 'DIscBIO-generic-DEGanalysis.R' + 'DIscBIO-generic-DEGanalysis2clust.R' + 'DIscBIO-generic-Exprmclust.R' + 'DIscBIO-generic-FinalPreprocessing.R' + 'DIscBIO-generic-FindOutliers.R' + 'DIscBIO-generic-NoiseFiltering.R' + 'DIscBIO-generic-Normalizedata.R' + 'DIscBIO-generic-PCAplotSymbols.R' + 'DIscBIO-generic-PlotmclustMB.R' + 'DIscBIO-generic-clusteringOrder.R' + 'DIscBIO-generic-clustheatmap.R' + 'DIscBIO-generic-comptSNE.R' + 'DIscBIO-generic-plotExptSNE.R' + 'DIscBIO-generic-plotGap.R' + 'DIscBIO-generic-plotLabelstSNE.R' + 'DIscBIO-generic-plotOrderTsne.R' + 'DIscBIO-generic-plotSilhouette.R' + 'DIscBIO-generic-plotSymbolstSNE.R' + 'DIscBIO-generic-plottSNE.R' + 'DIscBIO-generic-pseudoTimeOrdering.R' + 'J48DT.R' + 'J48DTeval.R' + 'Jaccard.R' + 'NetAnalysis.R' + 'Networking.R' + 'PPI.R' + 'PlotMBpca.R' + 'RpartDT.R' + 'RpartEVAL.R' + 'VolcanoPlot.R' + 'bootstrap.R' + 'calc_pcareduceres.R' + 'cross.val.R' + 'customConverters.R' + 'datasets.R' + 'internal-functions-samr-adapted.R' + 'internal-functions.R'