--- a
+++ b/asv_bench/benchmarks/fingerprints.py
@@ -0,0 +1,66 @@
+import os
+import oddt
+from oddt.fingerprints import (ECFP,
+                               _ECFP_atom_repr,
+                               _ECFP_atom_hash,
+                               PLEC)
+
+test_data_dir = os.path.join(os.path.dirname(os.path.abspath(__file__)), '..', '..')
+
+class BenchECFP(object):
+    goal_time = 0.5
+
+    def setup(self):
+        self.mols = list(oddt.toolkit.readfile('sdf', '%s/tests/data/dude/xiap/actives_docked.sdf' % test_data_dir))[:10]
+        for mol in self.mols:
+            mol.atom_dict
+
+    def time_ecfp(self):
+        for mol in self.mols:
+            ECFP(mol, depth=4)
+
+    def time_ecfp_dense(self):
+        for mol in self.mols:
+            ECFP(mol, depth=4, sparse=False)
+
+    def time_ecfp_pharm(self):
+        for mol in self.mols:
+            ECFP(mol, depth=4, use_pharm_features=True)
+
+    def time_ecfp_atom_repr(self):
+        for mol in self.mols:
+            for atom in mol.atoms:
+                if atom.atomicnum > 1:
+                    _ECFP_atom_repr(mol, atom.idx0)
+
+    def time_ecfp_atom_hash(self):
+        for mol in self.mols:
+            for atom in mol.atoms:
+                if atom.atomicnum > 1:
+                    _ECFP_atom_hash(mol, atom.idx0, depth=8)
+                    break  # one atom is enough
+
+
+class BenchPLEC(object):
+    def setup(self):
+        self.mols = list(oddt.toolkit.readfile('sdf', '%s/tests/data/dude/xiap/actives_docked.sdf' % test_data_dir))[:10]
+        for mol in self.mols:
+            mol.atom_dict
+
+        self.rec = list(oddt.toolkit.readfile('pdb', '%s/tests/data/dude/xiap/receptor_rdkit.pdb' % test_data_dir))[0]
+        self.rec.protein = True
+        self.rec.atom_dict
+
+    def time_plec(self):
+        for mol in self.mols:
+            PLEC(mol, self.rec, depth_ligand=2, depth_protein=4)
+
+
+class BenchPLECwithHs(BenchPLEC):
+    def setup(self):
+        super(BenchPLECwithHs, self).setup()
+        for mol in self.mols:
+            mol.addh()
+            mol.atom_dict
+        self.rec.addh()
+        self.rec.atom_dict