--- a
+++ b/notebooks/plot_reactome.ipynb
@@ -0,0 +1,96 @@
+{
+ "cells": [
+  {
+   "cell_type": "code",
+   "execution_count": 1,
+   "metadata": {},
+   "outputs": [],
+   "source": [
+    "%load_ext autoreload\n",
+    "%autoreload 2\n",
+    "\n",
+    "%matplotlib inline"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 2,
+   "metadata": {},
+   "outputs": [],
+   "source": [
+    "import sys"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 3,
+   "metadata": {},
+   "outputs": [],
+   "source": [
+    "sys.path.append('..')\n",
+    "\n",
+    "from pyMultiOmics.plots import download_reactome_diagram\n",
+    "from pyMultiOmics.constants import HOMO_SAPIENS"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 4,
+   "metadata": {},
+   "outputs": [
+    {
+     "name": "stderr",
+     "output_type": "stream",
+     "text": [
+      "2022-03-24 14:49:06.061 | DEBUG    | pyMultiOmics.plots:send_reactome_expression_data:86 - POSTing expression data to Reactome Analysis Service: https://reactome.org/AnalysisService/identifiers/?interactors=false&species=Homo%20sapiens&sortBy=ENTITIES_PVALUE&order=ASC&resource=TOTAL&pValue=1&includeDisease=true\n",
+      "2022-03-24 14:49:07.812 | DEBUG    | pyMultiOmics.plots:send_reactome_expression_data:90 - Received HTTP status code: 200\n",
+      "2022-03-24 14:49:07.817 | DEBUG    | pyMultiOmics.plots:parse_reactome_json:115 - Received expression analysis token: MjAyMjAzMjQxMDIxMjdfNDExOTA%3D\n",
+      "2022-03-24 14:49:08.834 | DEBUG    | pyMultiOmics.plots:download_reactome_diagram:67 - Image saved to reactome.png\n"
+     ]
+    }
+   ],
+   "source": [
+    "stId = 'R-HSA-70921'\n",
+    "out_file = 'reactome.png'\n",
+    "exp_dict = {\n",
+    "    'C00135': 1.0,           # kegg\n",
+    "    'C01342': 2.0,           # kegg\n",
+    "    '30817': 3.0,            # ChEBI\n",
+    "    'HAL': 4.0,              # gene name\n",
+    "    'ENSG00000172508': 5.0,  # ensembl\n",
+    "    'Q96NU7': 6.0            # uniprot\n",
+    "}\n",
+    "\n",
+    "download_reactome_diagram(stId, out_file, species=HOMO_SAPIENS, expression_dict=exp_dict)"
+   ]
+  },
+  {
+   "cell_type": "markdown",
+   "metadata": {},
+   "source": [
+    "![title](reactome.png)"
+   ]
+  }
+ ],
+ "metadata": {
+  "kernelspec": {
+   "display_name": "Python 3 (ipykernel)",
+   "language": "python",
+   "name": "python3"
+  },
+  "language_info": {
+   "codemirror_mode": {
+    "name": "ipython",
+    "version": 3
+   },
+   "file_extension": ".py",
+   "mimetype": "text/x-python",
+   "name": "python",
+   "nbconvert_exporter": "python",
+   "pygments_lexer": "ipython3",
+   "version": "3.10.1"
+  }
+ },
+ "nbformat": 4,
+ "nbformat_minor": 4
+}