--- a +++ b/README.md @@ -0,0 +1,66 @@ + +[] +(https://travis-ci.com/abodein/netOmics) + +[] +(https://www.gnu.org/licenses/gpl-3.0) + +# netOmics + +With netOmics, we go beyond integration by introducing an interpretation tool. +netOmics is a package for the creation and exploration of multi-omics networks. + +Depending on the provided dataset, it allows to create inference networks from +expression data but also interaction networks from knowledge databases. +After merging the sub-networks to obtain a global multi-omics network, +we propose network exploration methods using propoagation techniques to perform +functional prediction or identification of molecular mechanisms. + +Furthermore, the package has been developed for longitudinal multi-omics data +and can be used in conjunction with our previously published package timeOmics. + +for more examples, please visite +https://github.com/abodein/netOmics-case-studies + +## Installation + +### Latest `BioConductor` Release + +To install this package, start R (version "4.1") and enter: + +```r +if (!requireNamespace("BiocManager", quietly = TRUE)) + install.packages("BiocManager") + +BiocManager::install("netOmics") +``` + + +### Latest `GitHub` Version + +Install the devtools package in R, then load it and install the latest stable +version of `netOmics` from `GitHub` + +```r +## install devtools if not installed +if (!requireNamespace("devtools", quietly = TRUE)) + install.packages("devtools") +## install netOmics +devtools::install_github("abodein/netOmics") +``` + +## Citing + +*"Bodein, A., Scott-Boyer, M. P., Perin, O., Le Cao, K. A., & Droit, A. (2020). +Interpretation of network-based integration from multi-omics longitudinal data. +bioRxiv."* + +## Maintainer +Antoine Bodein (<antoine.bodein.1@ulaval.ca>) + +## Bugs/Feature requests + +If you have any bugs or feature requests, +[let us know](https://github.com/abodein/netOmics/issues). +Thanks! +