{
 "cells": [
  {
   "cell_type": "code",
   "execution_count": 1,
   "metadata": {},
   "outputs": [],
   "source": [
    "from __future__ import print_function\n",
    "import pandas as pd \n",
    "import matplotlib.pyplot as plt \n",
    "import numpy as np \n",
    "from scipy.stats import zscore\n",
    "import seaborn as sns\n",
    "import sys,os\n",
    "from mapper import expand, parse_mapping_table, apply_mappers\n",
    "%matplotlib  inline"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 2,
   "metadata": {},
   "outputs": [],
   "source": [
    "gene_id = \"ENTREZID\"\n",
    "raw_data_dir = \"/home/olya/SFU/Hossein/PDX/\" \n",
    "preprocessed_data_dir =  \"/home/olya/SFU/Hossein/v2/preprocessed/exprs/\"\n",
    "root_dir = \"/home/olya/SFU/Hossein/v2/\"\n",
    "# wget https://media.nature.com/original/nature-assets/nm/journal/v21/n11/extref/nm.3954-S2.xlsx\n",
    "# download Entrez ID mapping file"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "# PDX \n",
    "\n",
    "- for 22665 Gene symbols are converted to Gene IDs \n",
    "- gene expression profiles (FPKM) for 399 samples converted to log2(TPM+1)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "(22665, 399)\n"
     ]
    },
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>X-1004</th>\n",
       "      <th>X-1008</th>\n",
       "      <th>X-1027</th>\n",
       "      <th>X-1095</th>\n",
       "      <th>X-1119</th>\n",
       "      <th>X-1156</th>\n",
       "      <th>X-1167</th>\n",
       "      <th>X-1169</th>\n",
       "      <th>X-1172</th>\n",
       "      <th>X-1173</th>\n",
       "      <th>...</th>\n",
       "      <th>X-5713</th>\n",
       "      <th>X-5717</th>\n",
       "      <th>X-5727</th>\n",
       "      <th>X-5739</th>\n",
       "      <th>X-5808</th>\n",
       "      <th>X-5959</th>\n",
       "      <th>X-5974</th>\n",
       "      <th>X-5975</th>\n",
       "      <th>X-6030</th>\n",
       "      <th>X-6047</th>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>Sample</th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>A1BG</th>\n",
       "      <td>2.75</td>\n",
       "      <td>8.97</td>\n",
       "      <td>0.14</td>\n",
       "      <td>0.13</td>\n",
       "      <td>0.08</td>\n",
       "      <td>17.52</td>\n",
       "      <td>0.18</td>\n",
       "      <td>0.41</td>\n",
       "      <td>0.08</td>\n",
       "      <td>0.00</td>\n",
       "      <td>...</td>\n",
       "      <td>21.24</td>\n",
       "      <td>0.46</td>\n",
       "      <td>18.70</td>\n",
       "      <td>0.00</td>\n",
       "      <td>8.30</td>\n",
       "      <td>14.41</td>\n",
       "      <td>5.09</td>\n",
       "      <td>6.35</td>\n",
       "      <td>0.09</td>\n",
       "      <td>3.22</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>A1BG-AS1</th>\n",
       "      <td>2.48</td>\n",
       "      <td>3.25</td>\n",
       "      <td>0.00</td>\n",
       "      <td>0.00</td>\n",
       "      <td>0.00</td>\n",
       "      <td>6.52</td>\n",
       "      <td>0.00</td>\n",
       "      <td>0.00</td>\n",
       "      <td>0.00</td>\n",
       "      <td>0.00</td>\n",
       "      <td>...</td>\n",
       "      <td>15.21</td>\n",
       "      <td>0.09</td>\n",
       "      <td>3.42</td>\n",
       "      <td>0.00</td>\n",
       "      <td>8.30</td>\n",
       "      <td>8.36</td>\n",
       "      <td>3.71</td>\n",
       "      <td>4.52</td>\n",
       "      <td>0.00</td>\n",
       "      <td>3.24</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>A1CF</th>\n",
       "      <td>0.02</td>\n",
       "      <td>0.03</td>\n",
       "      <td>1.30</td>\n",
       "      <td>2.83</td>\n",
       "      <td>2.87</td>\n",
       "      <td>0.72</td>\n",
       "      <td>3.41</td>\n",
       "      <td>0.01</td>\n",
       "      <td>1.84</td>\n",
       "      <td>2.96</td>\n",
       "      <td>...</td>\n",
       "      <td>0.01</td>\n",
       "      <td>0.45</td>\n",
       "      <td>0.00</td>\n",
       "      <td>0.01</td>\n",
       "      <td>0.00</td>\n",
       "      <td>0.00</td>\n",
       "      <td>0.02</td>\n",
       "      <td>0.03</td>\n",
       "      <td>4.63</td>\n",
       "      <td>0.02</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>A2LD1</th>\n",
       "      <td>4.87</td>\n",
       "      <td>0.81</td>\n",
       "      <td>6.45</td>\n",
       "      <td>4.94</td>\n",
       "      <td>11.07</td>\n",
       "      <td>0.87</td>\n",
       "      <td>3.28</td>\n",
       "      <td>0.32</td>\n",
       "      <td>0.61</td>\n",
       "      <td>7.10</td>\n",
       "      <td>...</td>\n",
       "      <td>1.33</td>\n",
       "      <td>2.51</td>\n",
       "      <td>2.67</td>\n",
       "      <td>3.13</td>\n",
       "      <td>0.44</td>\n",
       "      <td>2.96</td>\n",
       "      <td>0.00</td>\n",
       "      <td>1.99</td>\n",
       "      <td>2.57</td>\n",
       "      <td>1.50</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>A2M</th>\n",
       "      <td>0.01</td>\n",
       "      <td>71.17</td>\n",
       "      <td>0.00</td>\n",
       "      <td>3.69</td>\n",
       "      <td>0.00</td>\n",
       "      <td>58.16</td>\n",
       "      <td>0.00</td>\n",
       "      <td>0.02</td>\n",
       "      <td>94.12</td>\n",
       "      <td>0.02</td>\n",
       "      <td>...</td>\n",
       "      <td>463.32</td>\n",
       "      <td>0.04</td>\n",
       "      <td>33.35</td>\n",
       "      <td>0.00</td>\n",
       "      <td>254.97</td>\n",
       "      <td>41.52</td>\n",
       "      <td>2.32</td>\n",
       "      <td>0.00</td>\n",
       "      <td>0.00</td>\n",
       "      <td>0.16</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "<p>5 rows × 399 columns</p>\n",
       "</div>"
      ],
      "text/plain": [
       "          X-1004  X-1008  X-1027  X-1095  X-1119  X-1156  X-1167  X-1169  \\\n",
       "Sample                                                                     \n",
       "A1BG        2.75    8.97    0.14    0.13    0.08   17.52    0.18    0.41   \n",
       "A1BG-AS1    2.48    3.25    0.00    0.00    0.00    6.52    0.00    0.00   \n",
       "A1CF        0.02    0.03    1.30    2.83    2.87    0.72    3.41    0.01   \n",
       "A2LD1       4.87    0.81    6.45    4.94   11.07    0.87    3.28    0.32   \n",
       "A2M         0.01   71.17    0.00    3.69    0.00   58.16    0.00    0.02   \n",
       "\n",
       "          X-1172  X-1173   ...    X-5713  X-5717  X-5727  X-5739  X-5808  \\\n",
       "Sample                     ...                                             \n",
       "A1BG        0.08    0.00   ...     21.24    0.46   18.70    0.00    8.30   \n",
       "A1BG-AS1    0.00    0.00   ...     15.21    0.09    3.42    0.00    8.30   \n",
       "A1CF        1.84    2.96   ...      0.01    0.45    0.00    0.01    0.00   \n",
       "A2LD1       0.61    7.10   ...      1.33    2.51    2.67    3.13    0.44   \n",
       "A2M        94.12    0.02   ...    463.32    0.04   33.35    0.00  254.97   \n",
       "\n",
       "          X-5959  X-5974  X-5975  X-6030  X-6047  \n",
       "Sample                                            \n",
       "A1BG       14.41    5.09    6.35    0.09    3.22  \n",
       "A1BG-AS1    8.36    3.71    4.52    0.00    3.24  \n",
       "A1CF        0.00    0.02    0.03    4.63    0.02  \n",
       "A2LD1       2.96    0.00    1.99    2.57    1.50  \n",
       "A2M        41.52    2.32    0.00    0.00    0.16  \n",
       "\n",
       "[5 rows x 399 columns]"
      ]
     },
     "execution_count": 3,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "exprs  = pd.read_excel(raw_data_dir+\"nm.3954-S2.xlsx\",\"RNAseq_fpkm\")\n",
    "exprs.set_index(\"Sample\",inplace=True,drop=True)\n",
    "print(exprs.shape)\n",
    "exprs.head() "
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "# Mapping of gene symbols to EntrezID using current gene_info file prowided by NCBI:\n",
    "\n",
    "\n",
    " * Download the unzip the file  \n",
    "\\# wget ftp://ftp.ncbi.nih.gov/gene/DATA/GENE_INFO/Mammalia/Homo_sapiens.gene_info.gz\n",
    "\\# gunzip Homo_sapiens.gene_info.gz;\n",
    " * Specify *hgnc_file* variable in this notebook\n",
    " * Mapping strategy\n",
    " \n",
    "1). Unknown genes and genes belonging to organisms other than H.sapiens were excluded.\n",
    "\n",
    "2). First each query symbol was tried to match with any of current \"Symbol\" directly. If the query symbol mapped to one of current symbol but has no Gene ID, the query symbol was marked as not mapped. \n",
    "\n",
    "3). If the query symbol matches none of current symbols, we tried to match it with one of \"Synonyms\". Genes matched no synonym as well as matched ambiguous synonyms correponding more than one Gene ID were condiered not mapped. \n",
    "\n",
    "4). At this point, many of not recognized symbols had LOCXXXXXXXXX format. \n",
    "According to the documntation provided by NCBI: \"Symbols beginning with LOC. When a published symbol is not available, and orthologs have not yet been determined, Gene will provide a symbol that is constructed as 'LOC' + the GeneID. This is not retained when a replacement symbol has been identified, although queries by the LOC term are still supported. In other words, a record with the symbol LOC12345 is equivalent to GeneID = 12345. So if the symbol changes, the record can still be retrieved on the web using LOC12345 as a query, or from any file using GeneID = 12345\" e.g. :\n",
    "\n",
    "    - LOC100093631 -> 100093631 \n",
    "    - LOC100129726 -> 100129726\n",
    "    - etc. \n",
    "\n",
    "Therefore all genes started with LOC were converted to Gene IDs removing \"LOC\" from query term. If resulting Gene ID matched none of current Gene IDs the symbol was considered not mapped. \n",
    "\n",
    "4). Several pairs of query gene symbols matched current symbol and synonym of the same Entrez gene ID, e.g. AGAP8 and AGAP4, ANXA8L1 and ANXA8L2, etc.\n",
    "Expressions of these genes were summarized because such genes were merged to a single gene in newer assembly versions."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 5,
   "metadata": {},
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "2547 rows with both Previous Symbols and Entrez Gene ID empty\n",
      "Ok: no duplicated pairs detected\n",
      "27336 rows with empty Previous Symbols were excluded\n",
      "173 Previous Symbols ids mapped to no Entrez Gene ID\n",
      "83 Previous Symbols mapped to multiple Entrez Gene ID\n",
      "4697 different Previous Symbols mapped to the same Entrez Gene ID\n",
      "9336 Previous Symbols can be mapped directly to Entrez Gene ID\n"
     ]
    }
   ],
   "source": [
    "hgnc_file = root_dir+\"HGNC_5.10.2018.txt\"\n",
    "\n",
    "hgnc = pd.read_csv(hgnc_file, sep =\"\\t\",index_col=0)#\n",
    "#print(hgnc.shape, len(set(hgnc.index.values)))\n",
    "approved = hgnc.loc[hgnc[\"Status\"] == \"Approved\",:]\n",
    "hgnc_prev =  expand(approved[[\"Previous Symbols\",\"Entrez Gene ID\"]],column=\"Previous Symbols\",sep=\", \") \n",
    "hgnc_prev = parse_mapping_table(hgnc_prev, \"Previous Symbols\",\"Entrez Gene ID\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 6,
   "metadata": {},
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "2224 rows with both Synonyms and Entrez Gene ID empty\n",
      "Ok: no duplicated pairs detected\n",
      "18283 rows with empty Synonyms were excluded\n",
      "662 Synonyms ids mapped to no Entrez Gene ID\n",
      "962 Synonyms mapped to multiple Entrez Gene ID\n",
      "27509 different Synonyms mapped to the same Entrez Gene ID\n",
      "10612 Synonyms can be mapped directly to Entrez Gene ID\n"
     ]
    }
   ],
   "source": [
    "hgnc_syn =  expand(approved[[\"Synonyms\",\"Entrez Gene ID\"]],column=\"Synonyms\",sep=\", \") \n",
    "hgnc_syn = parse_mapping_table(hgnc_syn, \"Synonyms\",\"Entrez Gene ID\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 7,
   "metadata": {},
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "Ok: no empty rows detected\n",
      "Ok: no duplicated pairs detected\n",
      "Ok: All Symbol rows are not empty.\n",
      "Ok: All Symbol are mapped to GeneID\n",
      "16 Symbol mapped to multiple GeneID\n",
      "Ok: All GeneID are unique\n",
      "59266 Symbol can be mapped directly to GeneID\n"
     ]
    }
   ],
   "source": [
    "NCBI = pd.read_csv(root_dir+\"Homo_sapiens.gene_info\",sep = \"\\t\")\n",
    "NCBI = NCBI[[\"#tax_id\",\"GeneID\",\"Symbol\",\"Synonyms\",\"type_of_gene\"]]\n",
    "NCBI = NCBI.loc[NCBI[\"#tax_id\"] == 9606]\n",
    "NCBI = NCBI.loc[NCBI[\"type_of_gene\"] != \"unknown\"]\n",
    "ncbi_symbols = parse_mapping_table(NCBI, \"Symbol\",\"GeneID\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 8,
   "metadata": {},
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "Ok: no empty rows detected\n",
      "Ok: no duplicated pairs detected\n",
      "Ok: All Synonyms rows are not empty.\n",
      "Ok: All Synonyms are mapped to GeneID\n",
      "3145 Synonyms mapped to multiple GeneID\n",
      "49179 different Synonyms mapped to the same GeneID\n",
      "10839 Synonyms can be mapped directly to GeneID\n"
     ]
    }
   ],
   "source": [
    "ncbi_synonyms = expand(NCBI[[\"Synonyms\",\"GeneID\"]],column=\"Synonyms\",sep=\"|\") \n",
    "ncbi_synonyms = parse_mapping_table(ncbi_synonyms, \"Synonyms\",\"GeneID\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 9,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Mapped: 22467 \n",
      "\tdirectly via main_mapper 20272 \n",
      "\tvia alternative mapper 471 \n",
      "\tvia one of multiple synonyms in alternative mapper 1026 \n",
      "\tLOC 698 \n",
      "Unmapped: 198 \n",
      "\trecognized symbols without Entrez ID 0 \n",
      "\tmultiple query_ids map to the same target_id 0 \n",
      "\tquery_ids map to multiple target_ids in the main mapper 0 \n",
      "\tquery_ids map to multiple target_ids in the alternative mapper 54 \n",
      "\tLOC not found in Entrez 26 \n",
      "\tNot found at all: 118\n",
      "Warning: query IDs mapping to duplicated target IDs in mapping table: 47\n",
      "Warning: query IDs not mapped to any target IDs excluded: 198\n"
     ]
    },
    {
     "ename": "AttributeError",
     "evalue": "'tuple' object has no attribute 'head'",
     "output_type": "error",
     "traceback": [
      "\u001b[0;31m---------------------------------------------------------------------------\u001b[0m",
      "\u001b[0;31mAttributeError\u001b[0m                            Traceback (most recent call last)",
      "\u001b[0;32m<ipython-input-9-c037e6e14d06>\u001b[0m in \u001b[0;36m<module>\u001b[0;34m()\u001b[0m\n\u001b[1;32m      1\u001b[0m \u001b[0mexprs\u001b[0m \u001b[0;34m=\u001b[0m \u001b[0mapply_mappers\u001b[0m\u001b[0;34m(\u001b[0m\u001b[0mexprs\u001b[0m\u001b[0;34m,\u001b[0m \u001b[0mncbi_symbols\u001b[0m\u001b[0;34m,\u001b[0m \u001b[0mncbi_synonyms\u001b[0m\u001b[0;34m,\u001b[0m \u001b[0mverbose\u001b[0m \u001b[0;34m=\u001b[0m \u001b[0mTrue\u001b[0m\u001b[0;34m,\u001b[0m\u001b[0mhandle_duplicates\u001b[0m \u001b[0;34m=\u001b[0m \u001b[0;34m\"sum\"\u001b[0m\u001b[0;34m)\u001b[0m\u001b[0;34m\u001b[0m\u001b[0m\n\u001b[0;32m----> 2\u001b[0;31m \u001b[0mexprs\u001b[0m\u001b[0;34m.\u001b[0m\u001b[0mhead\u001b[0m\u001b[0;34m(\u001b[0m\u001b[0;36m5\u001b[0m\u001b[0;34m)\u001b[0m\u001b[0;34m\u001b[0m\u001b[0m\n\u001b[0m",
      "\u001b[0;31mAttributeError\u001b[0m: 'tuple' object has no attribute 'head'"
     ]
    }
   ],
   "source": [
    "exprs = apply_mappers(exprs, ncbi_symbols, ncbi_synonyms, verbose = True,handle_duplicates = \"sum\")\n",
    "exprs.head(5)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "### FPKM to TPM conversion\n",
    "Let $X_i$ is a number of fragments mapped to a transcript, $N$ is a total number of fragments sequensed (and assigned to any transcript) and $\\widetilde{l_i}$  is an effective length of a transcript (i.e. how many fragments with average length $\\mu_{frag}$ can generate a transcript of length $l_i$: $\\widetilde{l_i} = l_i - \\mu_{frag}+1$)\n",
    "\n",
    "*FPKM* - fragments per kilobase of exon (i.e. effective length) per million reads mapped\n",
    "\n",
    "$FPKM_i = \\frac{X_i}{\\frac{$\\widetilde{l_i}}{10^3}*\\frac{N}{10^6}} = \\frac{X_i}{l_iN}*10^9 $\n",
    "\n",
    "*TPM* - transcripts per million of transcripts.\n",
    "\n",
    "In turn, $\\frac{X_i}{\\widetilde{l_i}}$ is estimated number of transcripts \n",
    "\n",
    "$TPM_i = \\frac{\\frac{X_i}{\\widetilde{l_i}}}{\\sum_j{\\frac{X_j}{\\widetilde{l_j}}}}*10^6 $\n",
    "\n",
    "\n",
    "### how to convert FPKM to TPM\n",
    "Divide both numerator and denominator by $N$ and mutiply by $10^9$:\n",
    "\n",
    "$TPM_i = \\frac{\\frac{X_i}{N\\widetilde{l_i}}*10^9}{\\sum_j{\\frac{X_j}{N\\widetilde{l_j}}*10^9}}*10^6 = \\frac{FPKM_i}{\\sum_j{FPKM_j}} * 10^6$\n",
    "\n",
    "Sources:\n",
    " - What the FPKM? https://haroldpimentel.wordpress.com/2014/05/08/what-the-fpkm-a-review-rna-seq-expression-units/\n",
    " - https://www.biostars.org/p/160989/\n",
    " - Lior Pachter https://arxiv.org/pdf/1104.3889.pdf\n"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {
    "scrolled": true
   },
   "outputs": [],
   "source": [
    "##  FPKM convert to log2(TPM+1)\n",
    "sum_fpkm = exprs.apply(sum,axis=0)\n",
    "sum_fpkm.head()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {},
   "outputs": [],
   "source": [
    "tpm = exprs / sum_fpkm *1000000 +1\n",
    "tpm.head()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {},
   "outputs": [],
   "source": [
    "\n",
    "tpm = tpm.applymap(np.log2)\n",
    "#tpm.to_csv(preprocessed_data_dir + \"/PDX.FPKM2TPMplus1log2.Expr.tsv\",sep=\"\\t\")\n",
    "print(tpm.shape)\n",
    "tpm.head()\n"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {},
   "outputs": [],
   "source": []
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "# TCGA \n",
    "\n",
    "* from http://gdac.broadinstitute.org/runs/stddata__2016_01_18/data/ download RSEM files, \"scaled estimate\" per gene. \n",
    "\n",
    "* RSEM Scaled estimate is an aboundance of a transcript divided by sum of aboundance over all the transcripts.  Therefore $TPM_i=ScaledEstimate_i*10^6$\n",
    "\n",
    "* Resulted TPM were log2-transformed"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "metadata": {},
   "outputs": [],
   "source": [
    "# replace with downloading \n",
    "tcga_tmp_dir = \"/home/olya/SFU/Hossein/TCGA/expression__2016_01_28/\""
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 10,
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "gdac.broadinstitute.org_BRCA.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 BRCA\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns 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have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "BRCA (20531, 1212)\n",
      "gdac.broadinstitute.org_STES.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 STES\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467,469,470,472,473,475,476,478,479,481,482,484,485,487,488,490,491,493,494,496,497,499,500,502,503,505,506,508,509,511,512,514,515,517,518,520,521,523,524,526,527,529,530,532,533,535,536,538,539,541,542,544,545,547,548,550,551,553,554,556,557,559,560,562,563,565,566,568,569,571,572,574,575,577,578,580,581,583,584,586,587,589,590,592,593,595,596,598,599,601,602,604,605,607,608,610,611,613,614,616,617,619,620,622,623,625,626,628,629,631,632,634,635,637,638,640,641,643,644,646,647,649,650,652,653,655,656,658,659,661,662,664,665,667,668,670,671,673,674,676,677,679,680,682,683,685,686,688,689,691,692,694,695,697,698,700,701,703,704,706,707,709,710,712,713,715,716,718,719,721,722,724,725,727,728,730,731,733,734,736,737,739,740,742,743,745,746,748,749,751,752,754,755,757,758,760,761,763,764,766,767,769,770,772,773,775,776,778,779,781,782,784,785,787,788,790,791,793,794,796,797,799,800,802,803,805,806,808,809,811,812,814,815,817,818,820,821,823,824,826,827,829,830,832,833,835,836,838,839,841,842,844,845,847,848,850,851,853,854,856,857,859,860,862,863,865,866,868,869,871,872,874,875,877,878,880,881,883,884,886,887,889,890,892,893,895,896,898,899,901,902,904,905,907,908,910,911,913,914,916,917,919,920,922,923,925,926,928,929,931,932,934,935,937,938,940,941,943,944,946,947,949,950,952,953,955,956,958,959,961,962,964,965,967,968,970,971,973,974,976,977,979,980,982,983,985,986,988,989,991,992,994,995,997,998,1000,1001,1003,1004,1006,1007,1009,1010,1012,1013,1015,1016,1018,1019,1021,1022,1024,1025,1027,1028,1030,1031,1033,1034,1036,1037,1039,1040,1042,1043,1045,1046,1048,1049,1051,1052,1054,1055,1057,1058,1060,1061,1063,1064,1066,1067,1069,1070,1072,1073,1075,1076,1078,1079,1081,1082,1084,1085,1087,1088,1090,1091,1093,1094,1096,1097,1099,1100,1102,1103,1105,1106,1108,1109,1111,1112,1114,1115,1117,1118,1120,1121,1123,1124,1126,1127,1129,1130,1132,1133,1135,1136,1138,1139,1141,1142,1144,1145,1147,1148,1150,1151,1153,1154,1156,1157,1159,1160,1162,1163,1165,1166,1168,1169,1171,1172,1174,1175,1177,1178,1180,1181,1183,1184,1186,1187,1189,1190,1192,1193,1195,1196,1198,1199,1201,1202,1204,1205,1207,1208,1210,1211,1213,1214,1216,1217,1219,1220,1222,1223,1225,1226,1228,1229,1231,1232,1234,1235,1237,1238,1240,1241,1243,1244,1246,1247,1249,1250,1252,1253,1255,1256,1258,1259,1261,1262,1264,1265,1267,1268,1270,1271,1273,1274,1276,1277,1279,1280,1282,1283,1285,1286,1288,1289,1291,1292,1294,1295,1297,1298,1300,1301,1303,1304,1306,1307,1309,1310,1312,1313,1315,1316,1318,1319,1321,1322,1324,1325,1327,1328,1330,1331,1333,1334,1336,1337,1339,1340,1342,1343,1345,1346,1348,1349,1351,1352,1354,1355,1357,1358,1360,1361,1363,1364,1366,1367,1369,1370,1372,1373,1375,1376,1378,1379,1381,1382,1384,1385,1387,1388,1390,1391,1393,1394,1396,1397,1399,1400,1402,1403,1405,1406,1408,1409,1411,1412,1414,1415,1417,1418,1420,1421,1423,1424,1426,1427,1429,1430,1432,1433,1435,1436,1438,1439,1441,1442,1444,1445,1447,1448,1450,1451,1453,1454,1456,1457,1459,1460,1462,1463,1465,1466,1468,1469,1471,1472,1474,1475,1477,1478,1480,1481,1483,1484,1486,1487,1489,1490,1492,1493,1495,1496,1498,1499,1501,1502,1504,1505,1507,1508,1510,1511,1513,1514,1516,1517,1519,1520,1522,1523,1525,1526,1528,1529,1531,1532,1534,1535,1537,1538,1540,1541,1543,1544,1546,1547,1549,1550,1552,1553,1555,1556,1558,1559,1561,1562,1564,1565,1567,1568,1570,1571,1573,1574,1576,1577,1579,1580,1582,1583,1585,1586,1588,1589,1591,1592,1594,1595,1597,1598,1600,1601,1603,1604,1606,1607,1609,1610,1612,1613,1615,1616,1618,1619,1621,1622,1624,1625,1627,1628,1630,1631,1633,1634,1636,1637,1639,1640,1642,1643,1645,1646,1648,1649,1651,1652,1654,1655,1657,1658,1660,1661,1663,1664,1666,1667,1669,1670,1672,1673,1675,1676,1678,1679,1681,1682,1684,1685,1687,1688,1690,1691,1693,1694,1696,1697,1699,1700,1702,1703,1705,1706,1708,1709,1711,1712,1714,1715,1717,1718,1720,17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have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "STES (20531, 646)\n",
      "gdac.broadinstitute.org_SKCM.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 SKCM\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467,469,470,472,473,475,476,478,479,481,482,484,485,487,488,490,491,493,494,496,497,499,500,502,503,505,506,508,509,511,512,514,515,517,518,520,521,523,524,526,527,529,530,532,533,535,536,538,539,541,542,544,545,547,548,550,551,553,554,556,557,559,560,562,563,565,566,568,569,571,572,574,575,577,578,580,581,583,584,586,587,589,590,592,593,595,596,598,599,601,602,604,605,607,608,610,611,613,614,616,617,619,620,622,623,625,626,628,629,631,632,634,635,637,638,640,641,643,644,646,647,649,650,652,653,655,656,658,659,661,662,664,665,667,668,670,671,673,674,676,677,679,680,682,683,685,686,688,689,691,692,694,695,697,698,700,701,703,704,706,707,709,710,712,713,715,716,718,719,721,722,724,725,727,728,730,731,733,734,736,737,739,740,742,743,745,746,748,749,751,752,754,755,757,758,760,761,763,764,766,767,769,770,772,773,775,776,778,779,781,782,784,785,787,788,790,791,793,794,796,797,799,800,802,803,805,806,808,809,811,812,814,815,817,818,820,821,823,824,826,827,829,830,832,833,835,836,838,839,841,842,844,845,847,848,850,851,853,854,856,857,859,860,862,863,865,866,868,869,871,872,874,875,877,878,880,881,883,884,886,887,889,890,892,893,895,896,898,899,901,902,904,905,907,908,910,911,913,914,916,917,919,920,922,923,925,926,928,929,931,932,934,935,937,938,940,941,943,944,946,947,949,950,952,953,955,956,958,959,961,962,964,965,967,968,970,971,973,974,976,977,979,980,982,983,985,986,988,989,991,992,994,995,997,998,1000,1001,1003,1004,1006,1007,1009,1010,1012,1013,1015,1016,1018,1019,1021,1022,1024,1025,1027,1028,1030,1031,1033,1034,1036,1037,1039,1040,1042,1043,1045,1046,1048,1049,1051,1052,1054,1055,1057,1058,1060,1061,1063,1064,1066,1067,1069,1070,1072,1073,1075,1076,1078,1079,1081,1082,1084,1085,1087,1088,1090,1091,1093,1094,1096,1097,1099,1100,1102,1103,1105,1106,1108,1109,1111,1112,1114,1115,1117,1118,1120,1121,1123,1124,1126,1127,1129,1130,1132,1133,1135,1136,1138,1139,1141,1142,1144,1145,1147,1148,1150,1151,1153,1154,1156,1157,1159,1160,1162,1163,1165,1166,1168,1169,1171,1172,1174,1175,1177,1178,1180,1181,1183,1184,1186,1187,1189,1190,1192,1193,1195,1196,1198,1199,1201,1202,1204,1205,1207,1208,1210,1211,1213,1214,1216,1217,1219,1220,1222,1223,1225,1226,1228,1229,1231,1232,1234,1235,1237,1238,1240,1241,1243,1244,1246,1247,1249,1250,1252,1253,1255,1256,1258,1259,1261,1262,1264,1265,1267,1268,1270,1271,1273,1274,1276,1277,1279,1280,1282,1283,1285,1286,1288,1289,1291,1292,1294,1295,1297,1298,1300,1301,1303,1304,1306,1307,1309,1310,1312,1313,1315,1316,1318,1319,1321,1322,1324,1325,1327,1328,1330,1331,1333,1334,1336,1337,1339,1340,1342,1343,1345,1346,1348,1349,1351,1352,1354,1355,1357,1358,1360,1361,1363,1364,1366,1367,1369,1370,1372,1373,1375,1376,1378,1379,1381,1382,1384,1385,1387,1388,1390,1391,1393,1394,1396,1397,1399,1400,1402,1403,1405,1406,1408,1409,1411,1412,1414,1415,1417,1418) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "SKCM (20531, 473)\n",
      "gdac.broadinstitute.org_PAAD.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 PAAD\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467,469,470,472,473,475,476,478,479,481,482,484,485,487,488,490,491,493,494,496,497,499,500,502,503,505,506,508,509,511,512,514,515,517,518,520,521,523,524,526,527,529,530,532,533,535,536,538,539,541,542,544,545,547,548) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "PAAD (20531, 183)\n",
      "gdac.broadinstitute.org_PCPG.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 PCPG\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467,469,470,472,473,475,476,478,479,481,482,484,485,487,488,490,491,493,494,496,497,499,500,502,503,505,506,508,509,511,512,514,515,517,518,520,521,523,524,526,527,529,530,532,533,535,536,538,539,541,542,544,545,547,548,550,551,553,554,556,557,559,560) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "PCPG (20531, 187)\n",
      "gdac.broadinstitute.org_UCS.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 UCS\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "UCS (20531, 57)\n",
      "gdac.broadinstitute.org_THCA.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 THCA\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns 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have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "THCA (20531, 568)\n",
      "gdac.broadinstitute.org_CESC.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 CESC\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467,469,470,472,473,475,476,478,479,481,482,484,485,487,488,490,491,493,494,496,497,499,500,502,503,505,506,508,509,511,512,514,515,517,518,520,521,523,524,526,527,529,530,532,533,535,536,538,539,541,542,544,545,547,548,550,551,553,554,556,557,559,560,562,563,565,566,568,569,571,572,574,575,577,578,580,581,583,584,586,587,589,590,592,593,595,596,598,599,601,602,604,605,607,608,610,611,613,614,616,617,619,620,622,623,625,626,628,629,631,632,634,635,637,638,640,641,643,644,646,647,649,650,652,653,655,656,658,659,661,662,664,665,667,668,670,671,673,674,676,677,679,680,682,683,685,686,688,689,691,692,694,695,697,698,700,701,703,704,706,707,709,710,712,713,715,716,718,719,721,722,724,725,727,728,730,731,733,734,736,737,739,740,742,743,745,746,748,749,751,752,754,755,757,758,760,761,763,764,766,767,769,770,772,773,775,776,778,779,781,782,784,785,787,788,790,791,793,794,796,797,799,800,802,803,805,806,808,809,811,812,814,815,817,818,820,821,823,824,826,827,829,830,832,833,835,836,838,839,841,842,844,845,847,848,850,851,853,854,856,857,859,860,862,863,865,866,868,869,871,872,874,875,877,878,880,881,883,884,886,887,889,890,892,893,895,896,898,899,901,902,904,905,907,908,910,911,913,914,916,917,919,920,922,923,925,926) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "CESC (20531, 309)\n",
      "gdac.broadinstitute.org_KIRP.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 KIRP\n"
     ]
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    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467,469,470,472,473,475,476,478,479,481,482,484,485,487,488,490,491,493,494,496,497,499,500,502,503,505,506,508,509,511,512,514,515,517,518,520,521,523,524,526,527,529,530,532,533,535,536,538,539,541,542,544,545,547,548,550,551,553,554,556,557,559,560,562,563,565,566,568,569,571,572,574,575,577,578,580,581,583,584,586,587,589,590,592,593,595,596,598,599,601,602,604,605,607,608,610,611,613,614,616,617,619,620,622,623,625,626,628,629,631,632,634,635,637,638,640,641,643,644,646,647,649,650,652,653,655,656,658,659,661,662,664,665,667,668,670,671,673,674,676,677,679,680,682,683,685,686,688,689,691,692,694,695,697,698,700,701,703,704,706,707,709,710,712,713,715,716,718,719,721,722,724,725,727,728,730,731,733,734,736,737,739,740,742,743,745,746,748,749,751,752,754,755,757,758,760,761,763,764,766,767,769,770,772,773,775,776,778,779,781,782,784,785,787,788,790,791,793,794,796,797,799,800,802,803,805,806,808,809,811,812,814,815,817,818,820,821,823,824,826,827,829,830,832,833,835,836,838,839,841,842,844,845,847,848,850,851,853,854,856,857,859,860,862,863,865,866,868,869,871,872,874,875,877,878,880,881,883,884,886,887,889,890,892,893,895,896,898,899,901,902,904,905,907,908,910,911,913,914,916,917,919,920,922,923,925,926,928,929,931,932,934,935,937,938,940,941,943,944,946,947,949,950,952,953,955,956,958,959,961,962,964,965,967,968) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "KIRP (20531, 323)\n",
      "gdac.broadinstitute.org_COAD.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 COAD\n"
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    {
     "name": "stderr",
     "output_type": "stream",
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      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467,469,470,472,473,475,476,478,479,481,482,484,485,487,488,490,491,493,494,496,497,499,500,502,503,505,506,508,509,511,512,514,515,517,518,520,521,523,524,526,527,529,530,532,533,535,536,538,539,541,542,544,545,547,548,550,551,553,554,556,557,559,560,562,563,565,566,568,569,571,572,574,575,577,578,580,581,583,584,586,587,589,590,592,593,595,596,598,599,601,602,604,605,607,608,610,611,613,614,616,617,619,620,622,623,625,626,628,629,631,632,634,635,637,638,640,641,643,644,646,647,649,650,652,653,655,656,658,659,661,662,664,665,667,668,670,671,673,674,676,677,679,680,682,683,685,686,688,689,691,692,694,695,697,698,700,701,703,704,706,707,709,710,712,713,715,716,718,719,721,722,724,725,727,728,730,731,733,734,736,737,739,740,742,743,745,746,748,749,751,752,754,755,757,758,760,761,763,764,766,767,769,770,772,773,775,776,778,779,781,782,784,785,787,788,790,791,793,794,796,797,799,800,802,803,805,806,808,809,811,812,814,815,817,818,820,821,823,824,826,827,829,830,832,833,835,836,838,839,841,842,844,845,847,848,850,851,853,854,856,857,859,860,862,863,865,866,868,869,871,872,874,875,877,878,880,881,883,884,886,887,889,890,892,893,895,896,898,899,901,902,904,905,907,908,910,911,913,914,916,917,919,920,922,923,925,926,928,929,931,932,934,935,937,938,940,941,943,944,946,947,949,950,952,953,955,956,958,959,961,962,964,965,967,968,970,971,973,974,976,977,979,980,982,983) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "COAD (20531, 328)\n",
      "gdac.broadinstitute.org_KIRC.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 KIRC\n"
     ]
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    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns 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have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "KIRC (20531, 606)\n",
      "gdac.broadinstitute.org_THYM.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 THYM\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "THYM (20531, 122)\n",
      "gdac.broadinstitute.org_LIHC.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 LIHC\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467,469,470,472,473,475,476,478,479,481,482,484,485,487,488,490,491,493,494,496,497,499,500,502,503,505,506,508,509,511,512,514,515,517,518,520,521,523,524,526,527,529,530,532,533,535,536,538,539,541,542,544,545,547,548,550,551,553,554,556,557,559,560,562,563,565,566,568,569,571,572,574,575,577,578,580,581,583,584,586,587,589,590,592,593,595,596,598,599,601,602,604,605,607,608,610,611,613,614,616,617,619,620,622,623,625,626,628,629,631,632,634,635,637,638,640,641,643,644,646,647,649,650,652,653,655,656,658,659,661,662,664,665,667,668,670,671,673,674,676,677,679,680,682,683,685,686,688,689,691,692,694,695,697,698,700,701,703,704,706,707,709,710,712,713,715,716,718,719,721,722,724,725,727,728,730,731,733,734,736,737,739,740,742,743,745,746,748,749,751,752,754,755,757,758,760,761,763,764,766,767,769,770,772,773,775,776,778,779,781,782,784,785,787,788,790,791,793,794,796,797,799,800,802,803,805,806,808,809,811,812,814,815,817,818,820,821,823,824,826,827,829,830,832,833,835,836,838,839,841,842,844,845,847,848,850,851,853,854,856,857,859,860,862,863,865,866,868,869,871,872,874,875,877,878,880,881,883,884,886,887,889,890,892,893,895,896,898,899,901,902,904,905,907,908,910,911,913,914,916,917,919,920,922,923,925,926,928,929,931,932,934,935,937,938,940,941,943,944,946,947,949,950,952,953,955,956,958,959,961,962,964,965,967,968,970,971,973,974,976,977,979,980,982,983,985,986,988,989,991,992,994,995,997,998,1000,1001,1003,1004,1006,1007,1009,1010,1012,1013,1015,1016,1018,1019,1021,1022,1024,1025,1027,1028,1030,1031,1033,1034,1036,1037,1039,1040,1042,1043,1045,1046,1048,1049,1051,1052,1054,1055,1057,1058,1060,1061,1063,1064,1066,1067,1069,1070,1072,1073,1075,1076,1078,1079,1081,1082,1084,1085,1087,1088,1090,1091,1093,1094,1096,1097,1099,1100,1102,1103,1105,1106,1108,1109,1111,1112,1114,1115,1117,1118,1120,1121,1123,1124,1126,1127,1129,1130,1132,1133,1135,1136,1138,1139,1141,1142,1144,1145,1147,1148,1150,1151,1153,1154,1156,1157,1159,1160,1162,1163,1165,1166,1168,1169,1171,1172,1174,1175,1177,1178,1180,1181,1183,1184,1186,1187,1189,1190,1192,1193,1195,1196,1198,1199,1201,1202,1204,1205,1207,1208,1210,1211,1213,1214,1216,1217,1219,1220,1222,1223,1225,1226,1228,1229,1231,1232,1234,1235,1237,1238,1240,1241,1243,1244,1246,1247,1249,1250,1252,1253,1255,1256,1258,1259,1261,1262,1264,1265,1267,1268) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "LIHC (20531, 423)\n",
      "gdac.broadinstitute.org_READ.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 READ\n"
     ]
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    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "READ (20531, 105)\n",
      "gdac.broadinstitute.org_GBM.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 GBM\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467,469,470,472,473,475,476,478,479,481,482,484,485,487,488,490,491,493,494,496,497,499,500,502,503,505,506,508,509,511,512) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "GBM (20531, 171)\n",
      "gdac.broadinstitute.org_LUAD.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 LUAD\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467,469,470,472,473,475,476,478,479,481,482,484,485,487,488,490,491,493,494,496,497,499,500,502,503,505,506,508,509,511,512,514,515,517,518,520,521,523,524,526,527,529,530,532,533,535,536,538,539,541,542,544,545,547,548,550,551,553,554,556,557,559,560,562,563,565,566,568,569,571,572,574,575,577,578,580,581,583,584,586,587,589,590,592,593,595,596,598,599,601,602,604,605,607,608,610,611,613,614,616,617,619,620,622,623,625,626,628,629,631,632,634,635,637,638,640,641,643,644,646,647,649,650,652,653,655,656,658,659,661,662,664,665,667,668,670,671,673,674,676,677,679,680,682,683,685,686,688,689,691,692,694,695,697,698,700,701,703,704,706,707,709,710,712,713,715,716,718,719,721,722,724,725,727,728,730,731,733,734,736,737,739,740,742,743,745,746,748,749,751,752,754,755,757,758,760,761,763,764,766,767,769,770,772,773,775,776,778,779,781,782,784,785,787,788,790,791,793,794,796,797,799,800,802,803,805,806,808,809,811,812,814,815,817,818,820,821,823,824,826,827,829,830,832,833,835,836,838,839,841,842,844,845,847,848,850,851,853,854,856,857,859,860,862,863,865,866,868,869,871,872,874,875,877,878,880,881,883,884,886,887,889,890,892,893,895,896,898,899,901,902,904,905,907,908,910,911,913,914,916,917,919,920,922,923,925,926,928,929,931,932,934,935,937,938,940,941,943,944,946,947,949,950,952,953,955,956,958,959,961,962,964,965,967,968,970,971,973,974,976,977,979,980,982,983,985,986,988,989,991,992,994,995,997,998,1000,1001,1003,1004,1006,1007,1009,1010,1012,1013,1015,1016,1018,1019,1021,1022,1024,1025,1027,1028,1030,1031,1033,1034,1036,1037,1039,1040,1042,1043,1045,1046,1048,1049,1051,1052,1054,1055,1057,1058,1060,1061,1063,1064,1066,1067,1069,1070,1072,1073,1075,1076,1078,1079,1081,1082,1084,1085,1087,1088,1090,1091,1093,1094,1096,1097,1099,1100,1102,1103,1105,1106,1108,1109,1111,1112,1114,1115,1117,1118,1120,1121,1123,1124,1126,1127,1129,1130,1132,1133,1135,1136,1138,1139,1141,1142,1144,1145,1147,1148,1150,1151,1153,1154,1156,1157,1159,1160,1162,1163,1165,1166,1168,1169,1171,1172,1174,1175,1177,1178,1180,1181,1183,1184,1186,1187,1189,1190,1192,1193,1195,1196,1198,1199,1201,1202,1204,1205,1207,1208,1210,1211,1213,1214,1216,1217,1219,1220,1222,1223,1225,1226,1228,1229,1231,1232,1234,1235,1237,1238,1240,1241,1243,1244,1246,1247,1249,1250,1252,1253,1255,1256,1258,1259,1261,1262,1264,1265,1267,1268,1270,1271,1273,1274,1276,1277,1279,1280,1282,1283,1285,1286,1288,1289,1291,1292,1294,1295,1297,1298,1300,1301,1303,1304,1306,1307,1309,1310,1312,1313,1315,1316,1318,1319,1321,1322,1324,1325,1327,1328,1330,1331,1333,1334,1336,1337,1339,1340,1342,1343,1345,1346,1348,1349,1351,1352,1354,1355,1357,1358,1360,1361,1363,1364,1366,1367,1369,1370,1372,1373,1375,1376,1378,1379,1381,1382,1384,1385,1387,1388,1390,1391,1393,1394,1396,1397,1399,1400,1402,1403,1405,1406,1408,1409,1411,1412,1414,1415,1417,1418,1420,1421,1423,1424,1426,1427,1429,1430,1432,1433,1435,1436,1438,1439,1441,1442,1444,1445,1447,1448,1450,1451,1453,1454,1456,1457,1459,1460,1462,1463,1465,1466,1468,1469,1471,1472,1474,1475,1477,1478,1480,1481,1483,1484,1486,1487,1489,1490,1492,1493,1495,1496,1498,1499,1501,1502,1504,1505,1507,1508,1510,1511,1513,1514,1516,1517,1519,1520,1522,1523,1525,1526,1528,1529,1531,1532,1534,1535,1537,1538,1540,1541,1543,1544,1546,1547,1549,1550,1552,1553,1555,1556,1558,1559,1561,1562,1564,1565,1567,1568,1570,1571,1573,1574,1576,1577,1579,1580,1582,1583,1585,1586,1588,1589,1591,1592,1594,1595,1597,1598,1600,1601,1603,1604,1606,1607,1609,1610,1612,1613,1615,1616,1618,1619,1621,1622,1624,1625,1627,1628,1630,1631,1633,1634,1636,1637,1639,1640,1642,1643,1645,1646,1648,1649,1651,1652,1654,1655,1657,1658,1660,1661,1663,1664,1666,1667,1669,1670,1672,1673,1675,1676,1678,1679,1681,1682,1684,1685,1687,1688,1690,1691,1693,1694,1696,1697,1699,1700,1702,1703,1705,1706,1708,1709,1711,1712,1714,1715,1717,1718,1720,1721,1723,1724,1726,1727) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "LUAD (20531, 576)\n",
      "gdac.broadinstitute.org_DLBC.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 DLBC\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "DLBC (20531, 48)\n",
      "gdac.broadinstitute.org_KICH.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 KICH\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "KICH (20531, 91)\n",
      "gdac.broadinstitute.org_CHOL.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 CHOL\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "CHOL (20531, 45)\n",
      "gdac.broadinstitute.org_UVM.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 UVM\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "UVM (20531, 80)\n",
      "gdac.broadinstitute.org_PRAD.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 PRAD\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467,469,470,472,473,475,476,478,479,481,482,484,485,487,488,490,491,493,494,496,497,499,500,502,503,505,506,508,509,511,512,514,515,517,518,520,521,523,524,526,527,529,530,532,533,535,536,538,539,541,542,544,545,547,548,550,551,553,554,556,557,559,560,562,563,565,566,568,569,571,572,574,575,577,578,580,581,583,584,586,587,589,590,592,593,595,596,598,599,601,602,604,605,607,608,610,611,613,614,616,617,619,620,622,623,625,626,628,629,631,632,634,635,637,638,640,641,643,644,646,647,649,650,652,653,655,656,658,659,661,662,664,665,667,668,670,671,673,674,676,677,679,680,682,683,685,686,688,689,691,692,694,695,697,698,700,701,703,704,706,707,709,710,712,713,715,716,718,719,721,722,724,725,727,728,730,731,733,734,736,737,739,740,742,743,745,746,748,749,751,752,754,755,757,758,760,761,763,764,766,767,769,770,772,773,775,776,778,779,781,782,784,785,787,788,790,791,793,794,796,797,799,800,802,803,805,806,808,809,811,812,814,815,817,818,820,821,823,824,826,827,829,830,832,833,835,836,838,839,841,842,844,845,847,848,850,851,853,854,856,857,859,860,862,863,865,866,868,869,871,872,874,875,877,878,880,881,883,884,886,887,889,890,892,893,895,896,898,899,901,902,904,905,907,908,910,911,913,914,916,917,919,920,922,923,925,926,928,929,931,932,934,935,937,938,940,941,943,944,946,947,949,950,952,953,955,956,958,959,961,962,964,965,967,968,970,971,973,974,976,977,979,980,982,983,985,986,988,989,991,992,994,995,997,998,1000,1001,1003,1004,1006,1007,1009,1010,1012,1013,1015,1016,1018,1019,1021,1022,1024,1025,1027,1028,1030,1031,1033,1034,1036,1037,1039,1040,1042,1043,1045,1046,1048,1049,1051,1052,1054,1055,1057,1058,1060,1061,1063,1064,1066,1067,1069,1070,1072,1073,1075,1076,1078,1079,1081,1082,1084,1085,1087,1088,1090,1091,1093,1094,1096,1097,1099,1100,1102,1103,1105,1106,1108,1109,1111,1112,1114,1115,1117,1118,1120,1121,1123,1124,1126,1127,1129,1130,1132,1133,1135,1136,1138,1139,1141,1142,1144,1145,1147,1148,1150,1151,1153,1154,1156,1157,1159,1160,1162,1163,1165,1166,1168,1169,1171,1172,1174,1175,1177,1178,1180,1181,1183,1184,1186,1187,1189,1190,1192,1193,1195,1196,1198,1199,1201,1202,1204,1205,1207,1208,1210,1211,1213,1214,1216,1217,1219,1220,1222,1223,1225,1226,1228,1229,1231,1232,1234,1235,1237,1238,1240,1241,1243,1244,1246,1247,1249,1250,1252,1253,1255,1256,1258,1259,1261,1262,1264,1265,1267,1268,1270,1271,1273,1274,1276,1277,1279,1280,1282,1283,1285,1286,1288,1289,1291,1292,1294,1295,1297,1298,1300,1301,1303,1304,1306,1307,1309,1310,1312,1313,1315,1316,1318,1319,1321,1322,1324,1325,1327,1328,1330,1331,1333,1334,1336,1337,1339,1340,1342,1343,1345,1346,1348,1349,1351,1352,1354,1355,1357,1358,1360,1361,1363,1364,1366,1367,1369,1370,1372,1373,1375,1376,1378,1379,1381,1382,1384,1385,1387,1388,1390,1391,1393,1394,1396,1397,1399,1400,1402,1403,1405,1406,1408,1409,1411,1412,1414,1415,1417,1418,1420,1421,1423,1424,1426,1427,1429,1430,1432,1433,1435,1436,1438,1439,1441,1442,1444,1445,1447,1448,1450,1451,1453,1454,1456,1457,1459,1460,1462,1463,1465,1466,1468,1469,1471,1472,1474,1475,1477,1478,1480,1481,1483,1484,1486,1487,1489,1490,1492,1493,1495,1496,1498,1499,1501,1502,1504,1505,1507,1508,1510,1511,1513,1514,1516,1517,1519,1520,1522,1523,1525,1526,1528,1529,1531,1532,1534,1535,1537,1538,1540,1541,1543,1544,1546,1547,1549,1550,1552,1553,1555,1556,1558,1559,1561,1562,1564,1565,1567,1568,1570,1571,1573,1574,1576,1577,1579,1580,1582,1583,1585,1586,1588,1589,1591,1592,1594,1595,1597,1598,1600,1601,1603,1604,1606,1607,1609,1610,1612,1613,1615,1616,1618,1619,1621,1622,1624,1625,1627,1628,1630,1631,1633,1634,1636,1637,1639,1640,1642,1643,1645,1646,1648,1649) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "PRAD (20531, 550)\n",
      "gdac.broadinstitute.org_UCEC.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 UCEC\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467,469,470,472,473,475,476,478,479,481,482,484,485,487,488,490,491,493,494,496,497,499,500,502,503,505,506,508,509,511,512,514,515,517,518,520,521,523,524,526,527,529,530,532,533,535,536,538,539,541,542,544,545,547,548,550,551,553,554,556,557,559,560,562,563,565,566,568,569,571,572,574,575,577,578,580,581,583,584,586,587,589,590,592,593,595,596,598,599,601,602) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "UCEC (20531, 201)\n",
      "gdac.broadinstitute.org_SARC.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 SARC\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467,469,470,472,473,475,476,478,479,481,482,484,485,487,488,490,491,493,494,496,497,499,500,502,503,505,506,508,509,511,512,514,515,517,518,520,521,523,524,526,527,529,530,532,533,535,536,538,539,541,542,544,545,547,548,550,551,553,554,556,557,559,560,562,563,565,566,568,569,571,572,574,575,577,578,580,581,583,584,586,587,589,590,592,593,595,596,598,599,601,602,604,605,607,608,610,611,613,614,616,617,619,620,622,623,625,626,628,629,631,632,634,635,637,638,640,641,643,644,646,647,649,650,652,653,655,656,658,659,661,662,664,665,667,668,670,671,673,674,676,677,679,680,682,683,685,686,688,689,691,692,694,695,697,698,700,701,703,704,706,707,709,710,712,713,715,716,718,719,721,722,724,725,727,728,730,731,733,734,736,737,739,740,742,743,745,746,748,749,751,752,754,755,757,758,760,761,763,764,766,767,769,770,772,773,775,776,778,779,781,782,784,785,787,788,790,791,793,794) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "SARC (20531, 265)\n",
      "gdac.broadinstitute.org_TGCT.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 TGCT\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "TGCT (20531, 156)\n",
      "gdac.broadinstitute.org_LGG.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 LGG\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467,469,470,472,473,475,476,478,479,481,482,484,485,487,488,490,491,493,494,496,497,499,500,502,503,505,506,508,509,511,512,514,515,517,518,520,521,523,524,526,527,529,530,532,533,535,536,538,539,541,542,544,545,547,548,550,551,553,554,556,557,559,560,562,563,565,566,568,569,571,572,574,575,577,578,580,581,583,584,586,587,589,590,592,593,595,596,598,599,601,602,604,605,607,608,610,611,613,614,616,617,619,620,622,623,625,626,628,629,631,632,634,635,637,638,640,641,643,644,646,647,649,650,652,653,655,656,658,659,661,662,664,665,667,668,670,671,673,674,676,677,679,680,682,683,685,686,688,689,691,692,694,695,697,698,700,701,703,704,706,707,709,710,712,713,715,716,718,719,721,722,724,725,727,728,730,731,733,734,736,737,739,740,742,743,745,746,748,749,751,752,754,755,757,758,760,761,763,764,766,767,769,770,772,773,775,776,778,779,781,782,784,785,787,788,790,791,793,794,796,797,799,800,802,803,805,806,808,809,811,812,814,815,817,818,820,821,823,824,826,827,829,830,832,833,835,836,838,839,841,842,844,845,847,848,850,851,853,854,856,857,859,860,862,863,865,866,868,869,871,872,874,875,877,878,880,881,883,884,886,887,889,890,892,893,895,896,898,899,901,902,904,905,907,908,910,911,913,914,916,917,919,920,922,923,925,926,928,929,931,932,934,935,937,938,940,941,943,944,946,947,949,950,952,953,955,956,958,959,961,962,964,965,967,968,970,971,973,974,976,977,979,980,982,983,985,986,988,989,991,992,994,995,997,998,1000,1001,1003,1004,1006,1007,1009,1010,1012,1013,1015,1016,1018,1019,1021,1022,1024,1025,1027,1028,1030,1031,1033,1034,1036,1037,1039,1040,1042,1043,1045,1046,1048,1049,1051,1052,1054,1055,1057,1058,1060,1061,1063,1064,1066,1067,1069,1070,1072,1073,1075,1076,1078,1079,1081,1082,1084,1085,1087,1088,1090,1091,1093,1094,1096,1097,1099,1100,1102,1103,1105,1106,1108,1109,1111,1112,1114,1115,1117,1118,1120,1121,1123,1124,1126,1127,1129,1130,1132,1133,1135,1136,1138,1139,1141,1142,1144,1145,1147,1148,1150,1151,1153,1154,1156,1157,1159,1160,1162,1163,1165,1166,1168,1169,1171,1172,1174,1175,1177,1178,1180,1181,1183,1184,1186,1187,1189,1190,1192,1193,1195,1196,1198,1199,1201,1202,1204,1205,1207,1208,1210,1211,1213,1214,1216,1217,1219,1220,1222,1223,1225,1226,1228,1229,1231,1232,1234,1235,1237,1238,1240,1241,1243,1244,1246,1247,1249,1250,1252,1253,1255,1256,1258,1259,1261,1262,1264,1265,1267,1268,1270,1271,1273,1274,1276,1277,1279,1280,1282,1283,1285,1286,1288,1289,1291,1292,1294,1295,1297,1298,1300,1301,1303,1304,1306,1307,1309,1310,1312,1313,1315,1316,1318,1319,1321,1322,1324,1325,1327,1328,1330,1331,1333,1334,1336,1337,1339,1340,1342,1343,1345,1346,1348,1349,1351,1352,1354,1355,1357,1358,1360,1361,1363,1364,1366,1367,1369,1370,1372,1373,1375,1376,1378,1379,1381,1382,1384,1385,1387,1388,1390,1391,1393,1394,1396,1397,1399,1400,1402,1403,1405,1406,1408,1409,1411,1412,1414,1415,1417,1418,1420,1421,1423,1424,1426,1427,1429,1430,1432,1433,1435,1436,1438,1439,1441,1442,1444,1445,1447,1448,1450,1451,1453,1454,1456,1457,1459,1460,1462,1463,1465,1466,1468,1469,1471,1472,1474,1475,1477,1478,1480,1481,1483,1484,1486,1487,1489,1490,1492,1493,1495,1496,1498,1499,1501,1502,1504,1505,1507,1508,1510,1511,1513,1514,1516,1517,1519,1520,1522,1523,1525,1526,1528,1529,1531,1532,1534,1535,1537,1538,1540,1541,1543,1544,1546,1547,1549,1550,1552,1553,1555,1556,1558,1559,1561,1562,1564,1565,1567,1568,1570,1571,1573,1574,1576,1577,1579,1580,1582,1583,1585,1586,1588,1589) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "LGG (20531, 530)\n",
      "gdac.broadinstitute.org_ESCA.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 ESCA\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467,469,470,472,473,475,476,478,479,481,482,484,485,487,488,490,491,493,494,496,497,499,500,502,503,505,506,508,509,511,512,514,515,517,518,520,521,523,524,526,527,529,530,532,533,535,536,538,539,541,542,544,545,547,548,550,551,553,554,556,557,559,560,562,563,565,566,568,569,571,572,574,575,577,578,580,581,583,584,586,587) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "ESCA (20531, 196)\n",
      "gdac.broadinstitute.org_ACC.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 ACC\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "ACC (20531, 79)\n",
      "gdac.broadinstitute.org_LAML.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 LAML\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467,469,470,472,473,475,476,478,479,481,482,484,485,487,488,490,491,493,494,496,497,499,500,502,503,505,506,508,509,511,512,514,515,517,518) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "LAML (20531, 173)\n",
      "gdac.broadinstitute.org_HNSC.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 HNSC\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns 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have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "HNSC (20531, 566)\n",
      "gdac.broadinstitute.org_MESO.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 MESO\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "MESO (20531, 87)\n",
      "gdac.broadinstitute.org_STAD.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 STAD\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467,469,470,472,473,475,476,478,479,481,482,484,485,487,488,490,491,493,494,496,497,499,500,502,503,505,506,508,509,511,512,514,515,517,518,520,521,523,524,526,527,529,530,532,533,535,536,538,539,541,542,544,545,547,548,550,551,553,554,556,557,559,560,562,563,565,566,568,569,571,572,574,575,577,578,580,581,583,584,586,587,589,590,592,593,595,596,598,599,601,602,604,605,607,608,610,611,613,614,616,617,619,620,622,623,625,626,628,629,631,632,634,635,637,638,640,641,643,644,646,647,649,650,652,653,655,656,658,659,661,662,664,665,667,668,670,671,673,674,676,677,679,680,682,683,685,686,688,689,691,692,694,695,697,698,700,701,703,704,706,707,709,710,712,713,715,716,718,719,721,722,724,725,727,728,730,731,733,734,736,737,739,740,742,743,745,746,748,749,751,752,754,755,757,758,760,761,763,764,766,767,769,770,772,773,775,776,778,779,781,782,784,785,787,788,790,791,793,794,796,797,799,800,802,803,805,806,808,809,811,812,814,815,817,818,820,821,823,824,826,827,829,830,832,833,835,836,838,839,841,842,844,845,847,848,850,851,853,854,856,857,859,860,862,863,865,866,868,869,871,872,874,875,877,878,880,881,883,884,886,887,889,890,892,893,895,896,898,899,901,902,904,905,907,908,910,911,913,914,916,917,919,920,922,923,925,926,928,929,931,932,934,935,937,938,940,941,943,944,946,947,949,950,952,953,955,956,958,959,961,962,964,965,967,968,970,971,973,974,976,977,979,980,982,983,985,986,988,989,991,992,994,995,997,998,1000,1001,1003,1004,1006,1007,1009,1010,1012,1013,1015,1016,1018,1019,1021,1022,1024,1025,1027,1028,1030,1031,1033,1034,1036,1037,1039,1040,1042,1043,1045,1046,1048,1049,1051,1052,1054,1055,1057,1058,1060,1061,1063,1064,1066,1067,1069,1070,1072,1073,1075,1076,1078,1079,1081,1082,1084,1085,1087,1088,1090,1091,1093,1094,1096,1097,1099,1100,1102,1103,1105,1106,1108,1109,1111,1112,1114,1115,1117,1118,1120,1121,1123,1124,1126,1127,1129,1130,1132,1133,1135,1136,1138,1139,1141,1142,1144,1145,1147,1148,1150,1151,1153,1154,1156,1157,1159,1160,1162,1163,1165,1166,1168,1169,1171,1172,1174,1175,1177,1178,1180,1181,1183,1184,1186,1187,1189,1190,1192,1193,1195,1196,1198,1199,1201,1202,1204,1205,1207,1208,1210,1211,1213,1214,1216,1217,1219,1220,1222,1223,1225,1226,1228,1229,1231,1232,1234,1235,1237,1238,1240,1241,1243,1244,1246,1247,1249,1250,1252,1253,1255,1256,1258,1259,1261,1262,1264,1265,1267,1268,1270,1271,1273,1274,1276,1277,1279,1280,1282,1283,1285,1286,1288,1289,1291,1292,1294,1295,1297,1298,1300,1301,1303,1304,1306,1307,1309,1310,1312,1313,1315,1316,1318,1319,1321,1322,1324,1325,1327,1328,1330,1331,1333,1334,1336,1337,1339,1340,1342,1343,1345,1346,1348,1349) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "STAD (20531, 450)\n",
      "gdac.broadinstitute.org_OV.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 OV\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467,469,470,472,473,475,476,478,479,481,482,484,485,487,488,490,491,493,494,496,497,499,500,502,503,505,506,508,509,511,512,514,515,517,518,520,521,523,524,526,527,529,530,532,533,535,536,538,539,541,542,544,545,547,548,550,551,553,554,556,557,559,560,562,563,565,566,568,569,571,572,574,575,577,578,580,581,583,584,586,587,589,590,592,593,595,596,598,599,601,602,604,605,607,608,610,611,613,614,616,617,619,620,622,623,625,626,628,629,631,632,634,635,637,638,640,641,643,644,646,647,649,650,652,653,655,656,658,659,661,662,664,665,667,668,670,671,673,674,676,677,679,680,682,683,685,686,688,689,691,692,694,695,697,698,700,701,703,704,706,707,709,710,712,713,715,716,718,719,721,722,724,725,727,728,730,731,733,734,736,737,739,740,742,743,745,746,748,749,751,752,754,755,757,758,760,761,763,764,766,767,769,770,772,773,775,776,778,779,781,782,784,785,787,788,790,791,793,794,796,797,799,800,802,803,805,806,808,809,811,812,814,815,817,818,820,821,823,824,826,827,829,830,832,833,835,836,838,839,841,842,844,845,847,848,850,851,853,854,856,857,859,860,862,863,865,866,868,869,871,872,874,875,877,878,880,881,883,884,886,887,889,890,892,893,895,896,898,899,901,902,904,905,907,908,910,911,913,914,916,917,919,920) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "OV (20531, 307)\n",
      "gdac.broadinstitute.org_BLCA.Merge_rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.Level_3.2016012800.0.0 BLCA\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "/home/olya/miniconda2/lib/python2.7/site-packages/IPython/core/interactiveshell.py:2714: DtypeWarning: Columns (1,2,4,5,7,8,10,11,13,14,16,17,19,20,22,23,25,26,28,29,31,32,34,35,37,38,40,41,43,44,46,47,49,50,52,53,55,56,58,59,61,62,64,65,67,68,70,71,73,74,76,77,79,80,82,83,85,86,88,89,91,92,94,95,97,98,100,101,103,104,106,107,109,110,112,113,115,116,118,119,121,122,124,125,127,128,130,131,133,134,136,137,139,140,142,143,145,146,148,149,151,152,154,155,157,158,160,161,163,164,166,167,169,170,172,173,175,176,178,179,181,182,184,185,187,188,190,191,193,194,196,197,199,200,202,203,205,206,208,209,211,212,214,215,217,218,220,221,223,224,226,227,229,230,232,233,235,236,238,239,241,242,244,245,247,248,250,251,253,254,256,257,259,260,262,263,265,266,268,269,271,272,274,275,277,278,280,281,283,284,286,287,289,290,292,293,295,296,298,299,301,302,304,305,307,308,310,311,313,314,316,317,319,320,322,323,325,326,328,329,331,332,334,335,337,338,340,341,343,344,346,347,349,350,352,353,355,356,358,359,361,362,364,365,367,368,370,371,373,374,376,377,379,380,382,383,385,386,388,389,391,392,394,395,397,398,400,401,403,404,406,407,409,410,412,413,415,416,418,419,421,422,424,425,427,428,430,431,433,434,436,437,439,440,442,443,445,446,448,449,451,452,454,455,457,458,460,461,463,464,466,467,469,470,472,473,475,476,478,479,481,482,484,485,487,488,490,491,493,494,496,497,499,500,502,503,505,506,508,509,511,512,514,515,517,518,520,521,523,524,526,527,529,530,532,533,535,536,538,539,541,542,544,545,547,548,550,551,553,554,556,557,559,560,562,563,565,566,568,569,571,572,574,575,577,578,580,581,583,584,586,587,589,590,592,593,595,596,598,599,601,602,604,605,607,608,610,611,613,614,616,617,619,620,622,623,625,626,628,629,631,632,634,635,637,638,640,641,643,644,646,647,649,650,652,653,655,656,658,659,661,662,664,665,667,668,670,671,673,674,676,677,679,680,682,683,685,686,688,689,691,692,694,695,697,698,700,701,703,704,706,707,709,710,712,713,715,716,718,719,721,722,724,725,727,728,730,731,733,734,736,737,739,740,742,743,745,746,748,749,751,752,754,755,757,758,760,761,763,764,766,767,769,770,772,773,775,776,778,779,781,782,784,785,787,788,790,791,793,794,796,797,799,800,802,803,805,806,808,809,811,812,814,815,817,818,820,821,823,824,826,827,829,830,832,833,835,836,838,839,841,842,844,845,847,848,850,851,853,854,856,857,859,860,862,863,865,866,868,869,871,872,874,875,877,878,880,881,883,884,886,887,889,890,892,893,895,896,898,899,901,902,904,905,907,908,910,911,913,914,916,917,919,920,922,923,925,926,928,929,931,932,934,935,937,938,940,941,943,944,946,947,949,950,952,953,955,956,958,959,961,962,964,965,967,968,970,971,973,974,976,977,979,980,982,983,985,986,988,989,991,992,994,995,997,998,1000,1001,1003,1004,1006,1007,1009,1010,1012,1013,1015,1016,1018,1019,1021,1022,1024,1025,1027,1028,1030,1031,1033,1034,1036,1037,1039,1040,1042,1043,1045,1046,1048,1049,1051,1052,1054,1055,1057,1058,1060,1061,1063,1064,1066,1067,1069,1070,1072,1073,1075,1076,1078,1079,1081,1082,1084,1085,1087,1088,1090,1091,1093,1094,1096,1097,1099,1100,1102,1103,1105,1106,1108,1109,1111,1112,1114,1115,1117,1118,1120,1121,1123,1124,1126,1127,1129,1130,1132,1133,1135,1136,1138,1139,1141,1142,1144,1145,1147,1148,1150,1151,1153,1154,1156,1157,1159,1160,1162,1163,1165,1166,1168,1169,1171,1172,1174,1175,1177,1178,1180,1181,1183,1184,1186,1187,1189,1190,1192,1193,1195,1196,1198,1199,1201,1202,1204,1205,1207,1208,1210,1211,1213,1214,1216,1217,1219,1220,1222,1223,1225,1226,1228,1229,1231,1232,1234,1235,1237,1238,1240,1241,1243,1244,1246,1247,1249,1250,1252,1253,1255,1256,1258,1259,1261,1262,1264,1265,1267,1268,1270,1271,1273,1274,1276,1277,1279,1280) have mixed types. Specify dtype option on import or set low_memory=False.\n",
      "  interactivity=interactivity, compiler=compiler, result=result)\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "BLCA (20531, 427)\n"
     ]
    }
   ],
   "source": [
    "f_ext = \".rnaseqv2__illuminahiseq_rnaseqv2__unc_edu__Level_3__RSEM_genes__data.data.txt\"\n",
    "for fpath in os.listdir(tcga_tmp_dir):\n",
    "    if fpath.startswith(\"gdac.broadinstitute.org\") and not fpath.endswith(\".tar.gz\") :\n",
    "        cohort = fpath.split(\"_\")[1].replace(\".Merge\",\"\")\n",
    "        #print(fpath, cohort)\n",
    "        fname = cohort + f_ext\n",
    "        try:\n",
    "            exprs = pd.read_csv(tcga_tmp_dir+\"/\"+fpath+\"/\"+fname,sep=\"\\t\",index_col=0)\n",
    "            # drop \"gene_id\" and keep only \"scaled_estimate\" columns\n",
    "            exprs = exprs.loc[:,exprs.T.loc[exprs.T[\"gene_id\"]==\"scaled_estimate\",:].index]\n",
    "            exprs = exprs.iloc[1:,]\n",
    "            exprs.rename(index = lambda x :  int(x.split(\"|\")[1]),\n",
    "                         columns = lambda x : x.replace(\".1\",\"\"),inplace = True)\n",
    "            exprs.index.name = \"ENTREZID\"\n",
    "            # convert scaled_extimates to log2(TPM+1)\n",
    "            exprs = exprs.applymap(lambda x : np.log2(float(x)*1000000+1))\n",
    "            exprs = exprs.sort_index()\n",
    "            exprs.to_csv(preprocessed_data_dir +\"TCGA-\"+cohort+\"_exprs.RSEMscaled_est2TPMplus1log2.tsv\",sep  =\"\\t\")\n",
    "            print(cohort,exprs.shape)\n",
    "        except:\n",
    "            print(cohort,\"No expression data.\")\n",
    "\n",
    "\n",
    "    "
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 14,
   "metadata": {},
   "outputs": [
    {
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       "      <th></th>\n",
       "      <th>TCGA-2F-A9KO-01A-11R-A38B-07</th>\n",
       "      <th>TCGA-2F-A9KP-01A-11R-A38B-07</th>\n",
       "      <th>TCGA-2F-A9KQ-01A-11R-A38B-07</th>\n",
       "      <th>TCGA-2F-A9KR-01A-11R-A38B-07</th>\n",
       "      <th>TCGA-2F-A9KT-01A-11R-A38B-07</th>\n",
       "      <th>TCGA-2F-A9KW-01A-11R-A38B-07</th>\n",
       "      <th>TCGA-4Z-AA7M-01A-11R-A39I-07</th>\n",
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       "      <th>TCGA-4Z-AA7O-01A-31R-A39I-07</th>\n",
       "      <th>TCGA-4Z-AA7Q-01A-11R-A39I-07</th>\n",
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       "      <th>TCGA-ZF-AA4X-01A-11R-A38B-07</th>\n",
       "      <th>TCGA-ZF-AA51-01A-21R-A39I-07</th>\n",
       "      <th>TCGA-ZF-AA52-01A-12R-A39I-07</th>\n",
       "      <th>TCGA-ZF-AA53-01A-11R-A39I-07</th>\n",
       "      <th>TCGA-ZF-AA54-01A-11R-A39I-07</th>\n",
       "      <th>TCGA-ZF-AA56-01A-31R-A39I-07</th>\n",
       "      <th>TCGA-ZF-AA58-01A-12R-A42T-07</th>\n",
       "      <th>TCGA-ZF-AA5H-01A-11R-A39I-07</th>\n",
       "      <th>TCGA-ZF-AA5N-01A-11R-A42T-07</th>\n",
       "      <th>TCGA-ZF-AA5P-01A-11R-A39I-07</th>\n",
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       "    <tr>\n",
       "      <th>ENTREZID</th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
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       "  <tbody>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>1.161494</td>\n",
       "      <td>0.622532</td>\n",
       "      <td>0.837536</td>\n",
       "      <td>1.063692</td>\n",
       "      <td>0.732667</td>\n",
       "      <td>0.912991</td>\n",
       "      <td>1.612974</td>\n",
       "      <td>2.076237</td>\n",
       "      <td>0.870337</td>\n",
       "      <td>2.222218</td>\n",
       "      <td>...</td>\n",
       "      <td>1.523498</td>\n",
       "      <td>1.944983</td>\n",
       "      <td>2.372653</td>\n",
       "      <td>3.792826</td>\n",
       "      <td>3.479011</td>\n",
       "      <td>1.405645</td>\n",
       "      <td>1.572033</td>\n",
       "      <td>0.802134</td>\n",
       "      <td>0.420320</td>\n",
       "      <td>1.271811</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>8.034762</td>\n",
       "      <td>7.703466</td>\n",
       "      <td>7.782663</td>\n",
       "      <td>6.971443</td>\n",
       "      <td>6.047535</td>\n",
       "      <td>8.625286</td>\n",
       "      <td>6.235450</td>\n",
       "      <td>9.710621</td>\n",
       "      <td>7.270054</td>\n",
       "      <td>7.775153</td>\n",
       "      <td>...</td>\n",
       "      <td>5.611083</td>\n",
       "      <td>8.084193</td>\n",
       "      <td>10.095678</td>\n",
       "      <td>7.316936</td>\n",
       "      <td>8.761957</td>\n",
       "      <td>8.294718</td>\n",
       "      <td>7.737907</td>\n",
       "      <td>7.179355</td>\n",
       "      <td>4.904007</td>\n",
       "      <td>11.189585</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>9</th>\n",
       "      <td>2.167711</td>\n",
       "      <td>2.047625</td>\n",
       "      <td>2.951153</td>\n",
       "      <td>1.890493</td>\n",
       "      <td>1.988667</td>\n",
       "      <td>2.454169</td>\n",
       "      <td>2.643622</td>\n",
       "      <td>3.141316</td>\n",
       "      <td>2.077357</td>\n",
       "      <td>1.675782</td>\n",
       "      <td>...</td>\n",
       "      <td>3.949491</td>\n",
       "      <td>1.548279</td>\n",
       "      <td>3.722545</td>\n",
       "      <td>1.132057</td>\n",
       "      <td>2.568140</td>\n",
       "      <td>2.522893</td>\n",
       "      <td>1.725319</td>\n",
       "      <td>1.461496</td>\n",
       "      <td>1.847315</td>\n",
       "      <td>2.535479</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.117556</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.289701</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.380386</td>\n",
       "      <td>0.056320</td>\n",
       "      <td>0.637087</td>\n",
       "      <td>...</td>\n",
       "      <td>0.505300</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.138816</td>\n",
       "      <td>0.048032</td>\n",
       "      <td>0.048921</td>\n",
       "      <td>0.229931</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.029659</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.285390</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12</th>\n",
       "      <td>2.467830</td>\n",
       "      <td>2.420112</td>\n",
       "      <td>0.644298</td>\n",
       "      <td>4.545485</td>\n",
       "      <td>0.052373</td>\n",
       "      <td>1.322490</td>\n",
       "      <td>0.434296</td>\n",
       "      <td>4.842291</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.817122</td>\n",
       "      <td>...</td>\n",
       "      <td>0.551129</td>\n",
       "      <td>1.555709</td>\n",
       "      <td>3.774938</td>\n",
       "      <td>0.661099</td>\n",
       "      <td>3.624965</td>\n",
       "      <td>4.513976</td>\n",
       "      <td>4.705967</td>\n",
       "      <td>1.681905</td>\n",
       "      <td>3.356545</td>\n",
       "      <td>7.470335</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13</th>\n",
       "      <td>1.607347</td>\n",
       "      <td>0.666421</td>\n",
       "      <td>2.125684</td>\n",
       "      <td>3.496252</td>\n",
       "      <td>0.287708</td>\n",
       "      <td>0.288064</td>\n",
       "      <td>0.244637</td>\n",
       "      <td>0.067852</td>\n",
       "      <td>7.387370</td>\n",
       "      <td>0.506860</td>\n",
       "      <td>...</td>\n",
       "      <td>1.877776</td>\n",
       "      <td>0.696837</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.186422</td>\n",
       "      <td>1.209302</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>2.687331</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14</th>\n",
       "      <td>6.712206</td>\n",
       "      <td>6.844482</td>\n",
       "      <td>6.394740</td>\n",
       "      <td>7.557387</td>\n",
       "      <td>6.178432</td>\n",
       "      <td>6.353666</td>\n",
       "      <td>6.690444</td>\n",
       "      <td>6.741365</td>\n",
       "      <td>7.059396</td>\n",
       "      <td>6.466467</td>\n",
       "      <td>...</td>\n",
       "      <td>6.842549</td>\n",
       "      <td>7.154221</td>\n",
       "      <td>6.930621</td>\n",
       "      <td>6.004271</td>\n",
       "      <td>7.079890</td>\n",
       "      <td>7.159629</td>\n",
       "      <td>7.005162</td>\n",
       "      <td>6.691151</td>\n",
       "      <td>7.000661</td>\n",
       "      <td>6.747745</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15</th>\n",
       "      <td>0.080575</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.211327</td>\n",
       "      <td>0.178252</td>\n",
       "      <td>0.086826</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.085150</td>\n",
       "      <td>0.130796</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.478062</td>\n",
       "      <td>...</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.147725</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.221314</td>\n",
       "      <td>0.091143</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.174953</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>16</th>\n",
       "      <td>6.763091</td>\n",
       "      <td>6.625150</td>\n",
       "      <td>6.082827</td>\n",
       "      <td>5.402623</td>\n",
       "      <td>5.592732</td>\n",
       "      <td>7.433563</td>\n",
       "      <td>5.714908</td>\n",
       "      <td>5.731613</td>\n",
       "      <td>5.883047</td>\n",
       "      <td>5.032016</td>\n",
       "      <td>...</td>\n",
       "      <td>5.766447</td>\n",
       "      <td>4.790307</td>\n",
       "      <td>5.707889</td>\n",
       "      <td>7.424335</td>\n",
       "      <td>8.709575</td>\n",
       "      <td>6.086463</td>\n",
       "      <td>6.234755</td>\n",
       "      <td>6.877003</td>\n",
       "      <td>5.877546</td>\n",
       "      <td>5.983488</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>18</th>\n",
       "      <td>3.988948</td>\n",
       "      <td>4.263293</td>\n",
       "      <td>4.377654</td>\n",
       "      <td>2.923749</td>\n",
       "      <td>4.049974</td>\n",
       "      <td>1.382311</td>\n",
       "      <td>4.889327</td>\n",
       "      <td>3.960333</td>\n",
       "      <td>4.559524</td>\n",
       "      <td>0.999417</td>\n",
       "      <td>...</td>\n",
       "      <td>2.835719</td>\n",
       "      <td>1.746883</td>\n",
       "      <td>2.499375</td>\n",
       "      <td>0.784887</td>\n",
       "      <td>1.138534</td>\n",
       "      <td>3.009449</td>\n",
       "      <td>1.090132</td>\n",
       "      <td>0.552370</td>\n",
       "      <td>2.801317</td>\n",
       "      <td>1.614018</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>19</th>\n",
       "      <td>2.616904</td>\n",
       "      <td>1.357553</td>\n",
       "      <td>2.887098</td>\n",
       "      <td>2.551879</td>\n",
       "      <td>3.340053</td>\n",
       "      <td>4.326013</td>\n",
       "      <td>3.255879</td>\n",
       "      <td>3.513993</td>\n",
       "      <td>1.193602</td>\n",
       "      <td>3.132178</td>\n",
       "      <td>...</td>\n",
       "      <td>2.267587</td>\n",
       "      <td>2.991613</td>\n",
       "      <td>2.091500</td>\n",
       "      <td>3.461593</td>\n",
       "      <td>4.309989</td>\n",
       "      <td>3.239834</td>\n",
       "      <td>2.865977</td>\n",
       "      <td>3.039675</td>\n",
       "      <td>4.248400</td>\n",
       "      <td>2.405480</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>20</th>\n",
       "      <td>1.961844</td>\n",
       "      <td>3.090204</td>\n",
       "      <td>2.750104</td>\n",
       "      <td>2.616212</td>\n",
       "      <td>4.824872</td>\n",
       "      <td>1.875221</td>\n",
       "      <td>3.087467</td>\n",
       "      <td>3.481200</td>\n",
       "      <td>2.447453</td>\n",
       "      <td>1.753626</td>\n",
       "      <td>...</td>\n",
       "      <td>3.753183</td>\n",
       "      <td>3.149116</td>\n",
       "      <td>3.950087</td>\n",
       "      <td>1.512966</td>\n",
       "      <td>3.063315</td>\n",
       "      <td>2.664546</td>\n",
       "      <td>2.239061</td>\n",
       "      <td>2.201044</td>\n",
       "      <td>4.033922</td>\n",
       "      <td>2.951935</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21</th>\n",
       "      <td>0.612701</td>\n",
       "      <td>2.171850</td>\n",
       "      <td>1.529668</td>\n",
       "      <td>0.874337</td>\n",
       "      <td>0.658170</td>\n",
       "      <td>3.151741</td>\n",
       "      <td>1.052042</td>\n",
       "      <td>2.201756</td>\n",
       "      <td>0.261264</td>\n",
       "      <td>1.009647</td>\n",
       "      <td>...</td>\n",
       "      <td>3.021527</td>\n",
       "      <td>1.113386</td>\n",
       "      <td>2.348143</td>\n",
       "      <td>0.415792</td>\n",
       "      <td>1.146891</td>\n",
       "      <td>0.973392</td>\n",
       "      <td>1.574075</td>\n",
       "      <td>0.609913</td>\n",
       "      <td>0.356479</td>\n",
       "      <td>3.029807</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>22</th>\n",
       "      <td>3.963608</td>\n",
       "      <td>3.558606</td>\n",
       "      <td>3.232821</td>\n",
       "      <td>4.034338</td>\n",
       "      <td>3.022397</td>\n",
       "      <td>2.919716</td>\n",
       "      <td>4.367590</td>\n",
       "      <td>3.606886</td>\n",
       "      <td>3.189884</td>\n",
       "      <td>3.521772</td>\n",
       "      <td>...</td>\n",
       "      <td>4.114507</td>\n",
       "      <td>3.389721</td>\n",
       "      <td>3.120593</td>\n",
       "      <td>3.509229</td>\n",
       "      <td>3.879658</td>\n",
       "      <td>3.396367</td>\n",
       "      <td>4.009166</td>\n",
       "      <td>3.136087</td>\n",
       "      <td>2.831521</td>\n",
       "      <td>3.356951</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23</th>\n",
       "      <td>5.866598</td>\n",
       "      <td>5.853114</td>\n",
       "      <td>5.628400</td>\n",
       "      <td>5.752864</td>\n",
       "      <td>5.695003</td>\n",
       "      <td>6.594964</td>\n",
       "      <td>6.738333</td>\n",
       "      <td>5.660017</td>\n",
       "      <td>5.480534</td>\n",
       "      <td>5.570752</td>\n",
       "      <td>...</td>\n",
       "      <td>6.430712</td>\n",
       "      <td>5.604658</td>\n",
       "      <td>5.590098</td>\n",
       "      <td>5.312926</td>\n",
       "      <td>6.285286</td>\n",
       "      <td>6.186670</td>\n",
       "      <td>6.549178</td>\n",
       "      <td>6.333991</td>\n",
       "      <td>5.442255</td>\n",
       "      <td>6.053878</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24</th>\n",
       "      <td>1.926233</td>\n",
       "      <td>0.045424</td>\n",
       "      <td>0.055199</td>\n",
       "      <td>0.088273</td>\n",
       "      <td>0.064751</td>\n",
       "      <td>1.128087</td>\n",
       "      <td>0.803342</td>\n",
       "      <td>0.963160</td>\n",
       "      <td>0.533395</td>\n",
       "      <td>0.066792</td>\n",
       "      <td>...</td>\n",
       "      <td>1.379999</td>\n",
       "      <td>0.300011</td>\n",
       "      <td>0.421376</td>\n",
       "      <td>1.882620</td>\n",
       "      <td>0.130356</td>\n",
       "      <td>2.567049</td>\n",
       "      <td>2.568703</td>\n",
       "      <td>0.173096</td>\n",
       "      <td>0.388828</td>\n",
       "      <td>0.104554</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>25</th>\n",
       "      <td>4.220049</td>\n",
       "      <td>4.463162</td>\n",
       "      <td>3.714227</td>\n",
       "      <td>4.611958</td>\n",
       "      <td>4.654495</td>\n",
       "      <td>4.446463</td>\n",
       "      <td>4.265416</td>\n",
       "      <td>5.059879</td>\n",
       "      <td>3.456701</td>\n",
       "      <td>3.441491</td>\n",
       "      <td>...</td>\n",
       "      <td>4.609126</td>\n",
       "      <td>3.930508</td>\n",
       "      <td>4.711956</td>\n",
       "      <td>4.138851</td>\n",
       "      <td>4.864261</td>\n",
       "      <td>4.814331</td>\n",
       "      <td>4.535544</td>\n",
       "      <td>4.680990</td>\n",
       "      <td>3.357347</td>\n",
       "      <td>5.748911</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26</th>\n",
       "      <td>1.534503</td>\n",
       "      <td>0.457208</td>\n",
       "      <td>1.656747</td>\n",
       "      <td>3.666896</td>\n",
       "      <td>0.465448</td>\n",
       "      <td>0.336673</td>\n",
       "      <td>0.304059</td>\n",
       "      <td>0.574648</td>\n",
       "      <td>0.489768</td>\n",
       "      <td>0.309481</td>\n",
       "      <td>...</td>\n",
       "      <td>1.756336</td>\n",
       "      <td>0.761530</td>\n",
       "      <td>0.596701</td>\n",
       "      <td>1.438399</td>\n",
       "      <td>0.121543</td>\n",
       "      <td>1.735965</td>\n",
       "      <td>0.430035</td>\n",
       "      <td>0.857632</td>\n",
       "      <td>0.090871</td>\n",
       "      <td>0.192650</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>27</th>\n",
       "      <td>3.009672</td>\n",
       "      <td>2.538702</td>\n",
       "      <td>2.058677</td>\n",
       "      <td>2.333097</td>\n",
       "      <td>2.186895</td>\n",
       "      <td>3.246505</td>\n",
       "      <td>2.840525</td>\n",
       "      <td>3.008115</td>\n",
       "      <td>1.988889</td>\n",
       "      <td>1.045557</td>\n",
       "      <td>...</td>\n",
       "      <td>2.060089</td>\n",
       "      <td>1.888903</td>\n",
       "      <td>1.985187</td>\n",
       "      <td>2.370396</td>\n",
       "      <td>3.736276</td>\n",
       "      <td>1.990344</td>\n",
       "      <td>3.346693</td>\n",
       "      <td>4.048708</td>\n",
       "      <td>1.476133</td>\n",
       "      <td>2.492175</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>28</th>\n",
       "      <td>3.553466</td>\n",
       "      <td>0.071613</td>\n",
       "      <td>4.043810</td>\n",
       "      <td>1.998537</td>\n",
       "      <td>3.651975</td>\n",
       "      <td>0.970909</td>\n",
       "      <td>0.049227</td>\n",
       "      <td>2.933275</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>4.048759</td>\n",
       "      <td>...</td>\n",
       "      <td>2.940057</td>\n",
       "      <td>0.047274</td>\n",
       "      <td>0.277321</td>\n",
       "      <td>0.241962</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>2.330907</td>\n",
       "      <td>0.033785</td>\n",
       "      <td>0.052927</td>\n",
       "      <td>0.293858</td>\n",
       "      <td>0.617408</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>29</th>\n",
       "      <td>4.252114</td>\n",
       "      <td>5.314371</td>\n",
       "      <td>4.405773</td>\n",
       "      <td>4.809010</td>\n",
       "      <td>4.823228</td>\n",
       "      <td>3.875454</td>\n",
       "      <td>4.548557</td>\n",
       "      <td>5.491118</td>\n",
       "      <td>4.567789</td>\n",
       "      <td>5.541956</td>\n",
       "      <td>...</td>\n",
       "      <td>6.306159</td>\n",
       "      <td>5.983578</td>\n",
       "      <td>4.841091</td>\n",
       "      <td>3.985534</td>\n",
       "      <td>5.395005</td>\n",
       "      <td>5.227438</td>\n",
       "      <td>5.352269</td>\n",
       "      <td>6.153357</td>\n",
       "      <td>4.272364</td>\n",
       "      <td>4.636339</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>30</th>\n",
       "      <td>6.283626</td>\n",
       "      <td>7.041333</td>\n",
       "      <td>6.944863</td>\n",
       "      <td>6.671349</td>\n",
       "      <td>6.951327</td>\n",
       "      <td>5.968195</td>\n",
       "      <td>6.568039</td>\n",
       "      <td>6.418584</td>\n",
       "      <td>6.085184</td>\n",
       "      <td>5.676482</td>\n",
       "      <td>...</td>\n",
       "      <td>7.011171</td>\n",
       "      <td>6.898103</td>\n",
       "      <td>6.407046</td>\n",
       "      <td>6.627765</td>\n",
       "      <td>4.923261</td>\n",
       "      <td>6.389457</td>\n",
       "      <td>6.324138</td>\n",
       "      <td>5.236563</td>\n",
       "      <td>6.822422</td>\n",
       "      <td>6.143988</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>31</th>\n",
       "      <td>4.650181</td>\n",
       "      <td>4.974986</td>\n",
       "      <td>4.473319</td>\n",
       "      <td>5.608256</td>\n",
       "      <td>5.003486</td>\n",
       "      <td>4.237128</td>\n",
       "      <td>4.899172</td>\n",
       "      <td>4.801196</td>\n",
       "      <td>4.411286</td>\n",
       "      <td>4.604509</td>\n",
       "      <td>...</td>\n",
       "      <td>5.489832</td>\n",
       "      <td>4.361208</td>\n",
       "      <td>4.499776</td>\n",
       "      <td>4.099796</td>\n",
       "      <td>4.310456</td>\n",
       "      <td>5.287507</td>\n",
       "      <td>3.789480</td>\n",
       "      <td>4.593572</td>\n",
       "      <td>4.810476</td>\n",
       "      <td>4.482980</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>32</th>\n",
       "      <td>1.287524</td>\n",
       "      <td>0.505654</td>\n",
       "      <td>0.763694</td>\n",
       "      <td>1.874325</td>\n",
       "      <td>0.733106</td>\n",
       "      <td>0.757118</td>\n",
       "      <td>1.871018</td>\n",
       "      <td>2.696572</td>\n",
       "      <td>0.690042</td>\n",
       "      <td>2.033386</td>\n",
       "      <td>...</td>\n",
       "      <td>2.531524</td>\n",
       "      <td>1.201789</td>\n",
       "      <td>2.071635</td>\n",
       "      <td>0.923636</td>\n",
       "      <td>1.525026</td>\n",
       "      <td>1.321938</td>\n",
       "      <td>1.662648</td>\n",
       "      <td>1.231275</td>\n",
       "      <td>0.364992</td>\n",
       "      <td>3.270376</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>33</th>\n",
       "      <td>0.407168</td>\n",
       "      <td>0.272536</td>\n",
       "      <td>0.191193</td>\n",
       "      <td>0.570630</td>\n",
       "      <td>0.159784</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.401075</td>\n",
       "      <td>0.162440</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.365014</td>\n",
       "      <td>...</td>\n",
       "      <td>2.082781</td>\n",
       "      <td>0.051872</td>\n",
       "      <td>0.023798</td>\n",
       "      <td>0.070492</td>\n",
       "      <td>0.118533</td>\n",
       "      <td>0.513203</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.269587</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.264252</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>34</th>\n",
       "      <td>4.699257</td>\n",
       "      <td>5.466270</td>\n",
       "      <td>5.665893</td>\n",
       "      <td>5.476256</td>\n",
       "      <td>3.955474</td>\n",
       "      <td>4.042493</td>\n",
       "      <td>5.060120</td>\n",
       "      <td>5.352350</td>\n",
       "      <td>4.347544</td>\n",
       "      <td>4.789519</td>\n",
       "      <td>...</td>\n",
       "      <td>6.376422</td>\n",
       "      <td>4.577791</td>\n",
       "      <td>3.492034</td>\n",
       "      <td>4.605242</td>\n",
       "      <td>4.283358</td>\n",
       "      <td>4.977100</td>\n",
       "      <td>4.716416</td>\n",
       "      <td>4.580350</td>\n",
       "      <td>3.954026</td>\n",
       "      <td>4.304655</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>35</th>\n",
       "      <td>4.221315</td>\n",
       "      <td>4.060692</td>\n",
       "      <td>5.565621</td>\n",
       "      <td>4.414742</td>\n",
       "      <td>4.286086</td>\n",
       "      <td>4.366536</td>\n",
       "      <td>4.255144</td>\n",
       "      <td>3.561433</td>\n",
       "      <td>3.889248</td>\n",
       "      <td>4.366157</td>\n",
       "      <td>...</td>\n",
       "      <td>4.455009</td>\n",
       "      <td>4.415570</td>\n",
       "      <td>4.746772</td>\n",
       "      <td>4.056638</td>\n",
       "      <td>3.347017</td>\n",
       "      <td>4.584887</td>\n",
       "      <td>3.579932</td>\n",
       "      <td>3.506765</td>\n",
       "      <td>4.248824</td>\n",
       "      <td>5.511854</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>36</th>\n",
       "      <td>2.546490</td>\n",
       "      <td>4.141481</td>\n",
       "      <td>4.002538</td>\n",
       "      <td>2.430160</td>\n",
       "      <td>2.272737</td>\n",
       "      <td>2.416162</td>\n",
       "      <td>3.025325</td>\n",
       "      <td>3.605907</td>\n",
       "      <td>3.095087</td>\n",
       "      <td>1.872858</td>\n",
       "      <td>...</td>\n",
       "      <td>2.938874</td>\n",
       "      <td>1.959830</td>\n",
       "      <td>1.615353</td>\n",
       "      <td>0.780055</td>\n",
       "      <td>2.305503</td>\n",
       "      <td>3.151896</td>\n",
       "      <td>1.116940</td>\n",
       "      <td>1.183204</td>\n",
       "      <td>1.778956</td>\n",
       "      <td>2.279470</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>37</th>\n",
       "      <td>8.221469</td>\n",
       "      <td>8.484431</td>\n",
       "      <td>8.220426</td>\n",
       "      <td>7.658984</td>\n",
       "      <td>7.298956</td>\n",
       "      <td>7.522056</td>\n",
       "      <td>7.826961</td>\n",
       "      <td>7.369623</td>\n",
       "      <td>8.441356</td>\n",
       "      <td>7.439627</td>\n",
       "      <td>...</td>\n",
       "      <td>8.781912</td>\n",
       "      <td>8.247836</td>\n",
       "      <td>8.192882</td>\n",
       "      <td>7.438942</td>\n",
       "      <td>7.362950</td>\n",
       "      <td>7.659910</td>\n",
       "      <td>7.255310</td>\n",
       "      <td>7.487467</td>\n",
       "      <td>8.403723</td>\n",
       "      <td>7.616378</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>38</th>\n",
       "      <td>4.277477</td>\n",
       "      <td>4.804687</td>\n",
       "      <td>4.168925</td>\n",
       "      <td>2.910270</td>\n",
       "      <td>3.432268</td>\n",
       "      <td>4.960705</td>\n",
       "      <td>4.294950</td>\n",
       "      <td>4.475646</td>\n",
       "      <td>2.691840</td>\n",
       "      <td>3.959515</td>\n",
       "      <td>...</td>\n",
       "      <td>4.490428</td>\n",
       "      <td>4.263302</td>\n",
       "      <td>4.684854</td>\n",
       "      <td>4.018424</td>\n",
       "      <td>5.138271</td>\n",
       "      <td>4.254429</td>\n",
       "      <td>4.615857</td>\n",
       "      <td>3.647883</td>\n",
       "      <td>4.821318</td>\n",
       "      <td>5.106815</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>...</th>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>100271722</th>\n",
       "      <td>1.381865</td>\n",
       "      <td>0.559305</td>\n",
       "      <td>2.507135</td>\n",
       "      <td>2.419759</td>\n",
       "      <td>2.330566</td>\n",
       "      <td>0.527452</td>\n",
       "      <td>1.290149</td>\n",
       "      <td>1.200610</td>\n",
       "      <td>1.584978</td>\n",
       "      <td>0.413451</td>\n",
       "      <td>...</td>\n",
       "      <td>1.857436</td>\n",
       "      <td>1.044742</td>\n",
       "      <td>1.666201</td>\n",
       "      <td>1.198038</td>\n",
       "      <td>1.466321</td>\n",
       "      <td>1.119355</td>\n",
       "      <td>0.912242</td>\n",
       "      <td>1.382247</td>\n",
       "      <td>0.201691</td>\n",
       "      <td>1.844866</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>100271831</th>\n",
       "      <td>2.886801</td>\n",
       "      <td>1.372946</td>\n",
       "      <td>3.480265</td>\n",
       "      <td>3.585413</td>\n",
       "      <td>3.752486</td>\n",
       "      <td>2.600814</td>\n",
       "      <td>1.559259</td>\n",
       "      <td>2.873348</td>\n",
       "      <td>3.187062</td>\n",
       "      <td>2.483700</td>\n",
       "      <td>...</td>\n",
       "      <td>2.684300</td>\n",
       "      <td>2.268963</td>\n",
       "      <td>4.460098</td>\n",
       "      <td>4.180091</td>\n",
       "      <td>3.717881</td>\n",
       "      <td>2.960833</td>\n",
       "      <td>3.142854</td>\n",
       "      <td>3.235265</td>\n",
       "      <td>3.947347</td>\n",
       "      <td>3.500957</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>100271832</th>\n",
       "      <td>0.000000</td>\n",
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       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.101151</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.073447</td>\n",
       "      <td>...</td>\n",
       "      <td>0.079084</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.076156</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>100271835</th>\n",
       "      <td>1.174398</td>\n",
       "      <td>0.086516</td>\n",
       "      <td>0.439386</td>\n",
       "      <td>0.387716</td>\n",
       "      <td>0.366027</td>\n",
       "      <td>1.112313</td>\n",
       "      <td>2.189107</td>\n",
       "      <td>1.305199</td>\n",
       "      <td>0.767436</td>\n",
       "      <td>0.521596</td>\n",
       "      <td>...</td>\n",
       "      <td>2.434429</td>\n",
       "      <td>1.578586</td>\n",
       "      <td>4.078831</td>\n",
       "      <td>1.537604</td>\n",
       "      <td>1.442136</td>\n",
       "      <td>0.560257</td>\n",
       "      <td>3.070388</td>\n",
       "      <td>0.290139</td>\n",
       "      <td>3.115400</td>\n",
       "      <td>2.146352</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>100271836</th>\n",
       "      <td>4.184755</td>\n",
       "      <td>3.800484</td>\n",
       "      <td>2.966304</td>\n",
       "      <td>3.708623</td>\n",
       "      <td>3.345557</td>\n",
       "      <td>2.628879</td>\n",
       "      <td>3.731009</td>\n",
       "      <td>3.673671</td>\n",
       "      <td>2.879152</td>\n",
       "      <td>1.792119</td>\n",
       "      <td>...</td>\n",
       "      <td>2.792174</td>\n",
       "      <td>1.910625</td>\n",
       "      <td>1.574269</td>\n",
       "      <td>1.408949</td>\n",
       "      <td>3.184371</td>\n",
       "      <td>2.954052</td>\n",
       "      <td>1.761250</td>\n",
       "      <td>2.324886</td>\n",
       "      <td>2.212781</td>\n",
       "      <td>2.272575</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>100271849</th>\n",
       "      <td>1.324908</td>\n",
       "      <td>1.796684</td>\n",
       "      <td>0.396215</td>\n",
       "      <td>2.046291</td>\n",
       "      <td>1.285535</td>\n",
       "      <td>1.621034</td>\n",
       "      <td>0.498564</td>\n",
       "      <td>4.324096</td>\n",
       "      <td>1.400875</td>\n",
       "      <td>2.327593</td>\n",
       "      <td>...</td>\n",
       "      <td>2.146905</td>\n",
       "      <td>2.099291</td>\n",
       "      <td>1.335053</td>\n",
       "      <td>1.070452</td>\n",
       "      <td>2.811217</td>\n",
       "      <td>1.928666</td>\n",
       "      <td>1.942872</td>\n",
       "      <td>1.679722</td>\n",
       "      <td>0.763542</td>\n",
       "      <td>2.142223</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>100272146</th>\n",
       "      <td>1.431248</td>\n",
       "      <td>1.258686</td>\n",
       "      <td>1.048321</td>\n",
       "      <td>1.689908</td>\n",
       "      <td>1.149648</td>\n",
       "      <td>0.882753</td>\n",
       "      <td>1.773980</td>\n",
       "      <td>1.153539</td>\n",
       "      <td>0.806941</td>\n",
       "      <td>1.016220</td>\n",
       "      <td>...</td>\n",
       "      <td>2.220002</td>\n",
       "      <td>0.971965</td>\n",
       "      <td>0.934767</td>\n",
       "      <td>0.105945</td>\n",
       "      <td>0.529838</td>\n",
       "      <td>0.834684</td>\n",
       "      <td>0.672756</td>\n",
       "      <td>1.000893</td>\n",
       "      <td>0.435765</td>\n",
       "      <td>0.602256</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>100272147</th>\n",
       "      <td>4.522154</td>\n",
       "      <td>4.166729</td>\n",
       "      <td>4.449916</td>\n",
       "      <td>4.585680</td>\n",
       "      <td>4.885539</td>\n",
       "      <td>3.887128</td>\n",
       "      <td>5.129546</td>\n",
       "      <td>4.113461</td>\n",
       "      <td>4.916463</td>\n",
       "      <td>3.606867</td>\n",
       "      <td>...</td>\n",
       "      <td>5.878317</td>\n",
       "      <td>3.876211</td>\n",
       "      <td>4.675443</td>\n",
       "      <td>4.671075</td>\n",
       "      <td>4.599586</td>\n",
       "      <td>4.571879</td>\n",
       "      <td>5.662731</td>\n",
       "      <td>5.320516</td>\n",
       "      <td>4.588917</td>\n",
       "      <td>4.575929</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>100272216</th>\n",
       "      <td>0.317102</td>\n",
       "      <td>0.186426</td>\n",
       "      <td>0.143926</td>\n",
       "      <td>0.228025</td>\n",
       "      <td>0.224785</td>\n",
       "      <td>0.358273</td>\n",
       "      <td>0.248630</td>\n",
       "      <td>0.490062</td>\n",
       "      <td>0.196283</td>\n",
       "      <td>0.183147</td>\n",
       "      <td>...</td>\n",
       "      <td>0.076785</td>\n",
       "      <td>0.211775</td>\n",
       "      <td>0.113839</td>\n",
       "      <td>0.062768</td>\n",
       "      <td>1.888743</td>\n",
       "      <td>0.543836</td>\n",
       "      <td>0.491928</td>\n",
       "      <td>0.038743</td>\n",
       "      <td>0.156490</td>\n",
       "      <td>0.027260</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>100272217</th>\n",
       "      <td>0.888558</td>\n",
       "      <td>1.081672</td>\n",
       "      <td>0.535628</td>\n",
       "      <td>1.875071</td>\n",
       "      <td>0.921858</td>\n",
       "      <td>0.507322</td>\n",
       "      <td>0.816486</td>\n",
       "      <td>0.395231</td>\n",
       "      <td>0.327062</td>\n",
       "      <td>0.488304</td>\n",
       "      <td>...</td>\n",
       "      <td>1.590953</td>\n",
       "      <td>0.640856</td>\n",
       "      <td>0.574010</td>\n",
       "      <td>0.210361</td>\n",
       "      <td>0.445683</td>\n",
       "      <td>0.571828</td>\n",
       "      <td>0.559745</td>\n",
       "      <td>0.433005</td>\n",
       "      <td>0.818466</td>\n",
       "      <td>0.503680</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>100272228</th>\n",
       "      <td>1.162634</td>\n",
       "      <td>0.969318</td>\n",
       "      <td>1.482511</td>\n",
       "      <td>1.483449</td>\n",
       "      <td>0.769280</td>\n",
       "      <td>0.272411</td>\n",
       "      <td>2.131252</td>\n",
       "      <td>1.101936</td>\n",
       "      <td>0.858047</td>\n",
       "      <td>1.873479</td>\n",
       "      <td>...</td>\n",
       "      <td>2.231822</td>\n",
       "      <td>0.542195</td>\n",
       "      <td>1.069636</td>\n",
       "      <td>0.187633</td>\n",
       "      <td>0.321110</td>\n",
       "      <td>0.826413</td>\n",
       "      <td>0.900913</td>\n",
       "      <td>0.489285</td>\n",
       "      <td>0.350919</td>\n",
       "      <td>0.683409</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>100286793</th>\n",
       "      <td>3.749544</td>\n",
       "      <td>3.279243</td>\n",
       "      <td>2.472683</td>\n",
       "      <td>4.429526</td>\n",
       "      <td>3.590167</td>\n",
       "      <td>2.512924</td>\n",
       "      <td>4.620199</td>\n",
       "      <td>2.752506</td>\n",
       "      <td>2.475664</td>\n",
       "      <td>4.030156</td>\n",
       "      <td>...</td>\n",
       "      <td>2.899274</td>\n",
       "      <td>3.363391</td>\n",
       "      <td>2.931948</td>\n",
       "      <td>3.169480</td>\n",
       "      <td>3.779393</td>\n",
       "      <td>2.941597</td>\n",
       "      <td>4.904492</td>\n",
       "      <td>4.198462</td>\n",
       "      <td>2.336612</td>\n",
       "      <td>3.119572</td>\n",
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       "    <tr>\n",
       "      <th>100286844</th>\n",
       "      <td>0.577625</td>\n",
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       "      <td>0.664894</td>\n",
       "      <td>0.509770</td>\n",
       "      <td>0.269866</td>\n",
       "      <td>1.027578</td>\n",
       "      <td>0.293341</td>\n",
       "      <td>0.420398</td>\n",
       "      <td>0.283191</td>\n",
       "      <td>...</td>\n",
       "      <td>0.905923</td>\n",
       "      <td>0.299887</td>\n",
       "      <td>0.299501</td>\n",
       "      <td>0.202525</td>\n",
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       "    <tr>\n",
       "      <th>100287227</th>\n",
       "      <td>0.478071</td>\n",
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       "      <td>0.284478</td>\n",
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       "      <td>0.488973</td>\n",
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       "      <td>0.159785</td>\n",
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       "      <td>0.164729</td>\n",
       "      <td>...</td>\n",
       "      <td>0.432181</td>\n",
       "      <td>0.238998</td>\n",
       "      <td>0.406512</td>\n",
       "      <td>0.025150</td>\n",
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       "    <tr>\n",
       "      <th>100287569</th>\n",
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       "      <td>0.647825</td>\n",
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       "      <td>0.297210</td>\n",
       "      <td>0.268763</td>\n",
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       "    <tr>\n",
       "      <th>100287704</th>\n",
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       "      <td>0.000000</td>\n",
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       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
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       "    <tr>\n",
       "      <th>100287718</th>\n",
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       "      <td>0.000000</td>\n",
       "      <td>...</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
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       "    <tr>\n",
       "      <th>100288380</th>\n",
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       "      <td>0.186226</td>\n",
       "      <td>...</td>\n",
       "      <td>0.483296</td>\n",
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       "    <tr>\n",
       "      <th>100288778</th>\n",
       "      <td>6.790537</td>\n",
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       "      <td>5.916186</td>\n",
       "      <td>5.359674</td>\n",
       "      <td>5.232589</td>\n",
       "      <td>4.997729</td>\n",
       "      <td>...</td>\n",
       "      <td>6.593197</td>\n",
       "      <td>4.981928</td>\n",
       "      <td>6.003078</td>\n",
       "      <td>5.389232</td>\n",
       "      <td>5.606450</td>\n",
       "      <td>5.122558</td>\n",
       "      <td>5.558330</td>\n",
       "      <td>4.949391</td>\n",
       "      <td>6.165033</td>\n",
       "      <td>6.198619</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>100288801</th>\n",
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       "      <td>0.093848</td>\n",
       "      <td>...</td>\n",
       "      <td>0.051291</td>\n",
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       "    <tr>\n",
       "      <th>100289341</th>\n",
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       "      <td>0.809817</td>\n",
       "      <td>1.299766</td>\n",
       "      <td>0.808111</td>\n",
       "      <td>0.659194</td>\n",
       "      <td>...</td>\n",
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       "<p>20531 rows × 427 columns</p>\n",
       "</div>"
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      "text/plain": [
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       "ENTREZID                                                                \n",
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       "14                             6.690444                      6.741365   \n",
       "15                             0.085150                      0.130796   \n",
       "16                             5.714908                      5.731613   \n",
       "18                             4.889327                      3.960333   \n",
       "19                             3.255879                      3.513993   \n",
       "20                             3.087467                      3.481200   \n",
       "21                             1.052042                      2.201756   \n",
       "22                             4.367590                      3.606886   \n",
       "23                             6.738333                      5.660017   \n",
       "24                             0.803342                      0.963160   \n",
       "25                             4.265416                      5.059879   \n",
       "26                             0.304059                      0.574648   \n",
       "27                             2.840525                      3.008115   \n",
       "28                             0.049227                      2.933275   \n",
       "29                             4.548557                      5.491118   \n",
       "30                             6.568039                      6.418584   \n",
       "31                             4.899172                      4.801196   \n",
       "32                             1.871018                      2.696572   \n",
       "33                             0.401075                      0.162440   \n",
       "34                             5.060120                      5.352350   \n",
       "35                             4.255144                      3.561433   \n",
       "36                             3.025325                      3.605907   \n",
       "37                             7.826961                      7.369623   \n",
       "38                             4.294950                      4.475646   \n",
       "...                                 ...                           ...   \n",
       "100271722                      1.290149                      1.200610   \n",
       "100271831                      1.559259                      2.873348   \n",
       "100271832                      0.101151                      0.000000   \n",
       "100271835                      2.189107                      1.305199   \n",
       "100271836                      3.731009                      3.673671   \n",
       "100271849                      0.498564                      4.324096   \n",
       "100272146                      1.773980                      1.153539   \n",
       "100272147                      5.129546                      4.113461   \n",
       "100272216                      0.248630                      0.490062   \n",
       "100272217                      0.816486                      0.395231   \n",
       "100272228                      2.131252                      1.101936   \n",
       "100286793                      4.620199                      2.752506   \n",
       "100286844                      1.027578                      0.293341   \n",
       "100287227                      0.316336                      0.159785   \n",
       "100287569                      0.000000                      0.637993   \n",
       "100287704                      0.000000                      0.000000   \n",
       "100287718                      0.000000                      0.000000   \n",
       "100288380                      0.000000                      0.378000   \n",
       "100288778                      5.916186                      5.359674   \n",
       "100288801                      0.000000                      0.000000   \n",
       "100289341                      0.809817                      1.299766   \n",
       "100289635                      3.855801                      3.120055   \n",
       "100294720                      0.000000                      0.000000   \n",
       "100302401                      1.082908                      0.427754   \n",
       "100302640                      0.793848                      0.076033   \n",
       "100302650                      0.826337                      4.768559   \n",
       "100302692                      1.929626                      0.876302   \n",
       "100302736                      0.234748                      0.608218   \n",
       "100303453                      0.217259                      0.000000   \n",
       "100303728                      1.135417                      0.860897   \n",
       "\n",
       "           TCGA-4Z-AA7O-01A-31R-A39I-07  TCGA-4Z-AA7Q-01A-11R-A39I-07  \\\n",
       "ENTREZID                                                                \n",
       "1                              0.870337                      2.222218   \n",
       "2                              7.270054                      7.775153   \n",
       "9                              2.077357                      1.675782   \n",
       "10                             0.056320                      0.637087   \n",
       "12                             0.000000                      0.817122   \n",
       "13                             7.387370                      0.506860   \n",
       "14                             7.059396                      6.466467   \n",
       "15                             0.000000                      0.478062   \n",
       "16                             5.883047                      5.032016   \n",
       "18                             4.559524                      0.999417   \n",
       "19                             1.193602                      3.132178   \n",
       "20                             2.447453                      1.753626   \n",
       "21                             0.261264                      1.009647   \n",
       "22                             3.189884                      3.521772   \n",
       "23                             5.480534                      5.570752   \n",
       "24                             0.533395                      0.066792   \n",
       "25                             3.456701                      3.441491   \n",
       "26                             0.489768                      0.309481   \n",
       "27                             1.988889                      1.045557   \n",
       "28                             0.000000                      4.048759   \n",
       "29                             4.567789                      5.541956   \n",
       "30                             6.085184                      5.676482   \n",
       "31                             4.411286                      4.604509   \n",
       "32                             0.690042                      2.033386   \n",
       "33                             0.000000                      0.365014   \n",
       "34                             4.347544                      4.789519   \n",
       "35                             3.889248                      4.366157   \n",
       "36                             3.095087                      1.872858   \n",
       "37                             8.441356                      7.439627   \n",
       "38                             2.691840                      3.959515   \n",
       "...                                 ...                           ...   \n",
       "100271722                      1.584978                      0.413451   \n",
       "100271831                      3.187062                      2.483700   \n",
       "100271832                      0.000000                      0.073447   \n",
       "100271835                      0.767436                      0.521596   \n",
       "100271836                      2.879152                      1.792119   \n",
       "100271849                      1.400875                      2.327593   \n",
       "100272146                      0.806941                      1.016220   \n",
       "100272147                      4.916463                      3.606867   \n",
       "100272216                      0.196283                      0.183147   \n",
       "100272217                      0.327062                      0.488304   \n",
       "100272228                      0.858047                      1.873479   \n",
       "100286793                      2.475664                      4.030156   \n",
       "100286844                      0.420398                      0.283191   \n",
       "100287227                      0.207284                      0.164729   \n",
       "100287569                      0.000000                      0.647825   \n",
       "100287704                      0.000000                      0.000000   \n",
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       "100288380                      0.178236                      0.186226   \n",
       "100288778                      5.232589                      4.997729   \n",
       "100288801                      0.000000                      0.093848   \n",
       "100289341                      0.808111                      0.659194   \n",
       "100289635                      3.680738                      3.217935   \n",
       "100294720                      0.000000                      0.030316   \n",
       "100302401                      0.756725                      0.145178   \n",
       "100302640                      0.000000                      0.477775   \n",
       "100302650                      0.796422                      0.823880   \n",
       "100302692                      0.727365                      0.428572   \n",
       "100302736                      0.297075                      0.860072   \n",
       "100303453                      0.000000                      0.000000   \n",
       "100303728                      0.457222                      0.802506   \n",
       "\n",
       "                       ...               TCGA-ZF-AA4X-01A-11R-A38B-07  \\\n",
       "ENTREZID               ...                                              \n",
       "1                      ...                                   1.523498   \n",
       "2                      ...                                   5.611083   \n",
       "9                      ...                                   3.949491   \n",
       "10                     ...                                   0.505300   \n",
       "12                     ...                                   0.551129   \n",
       "13                     ...                                   1.877776   \n",
       "14                     ...                                   6.842549   \n",
       "15                     ...                                   0.000000   \n",
       "16                     ...                                   5.766447   \n",
       "18                     ...                                   2.835719   \n",
       "19                     ...                                   2.267587   \n",
       "20                     ...                                   3.753183   \n",
       "21                     ...                                   3.021527   \n",
       "22                     ...                                   4.114507   \n",
       "23                     ...                                   6.430712   \n",
       "24                     ...                                   1.379999   \n",
       "25                     ...                                   4.609126   \n",
       "26                     ...                                   1.756336   \n",
       "27                     ...                                   2.060089   \n",
       "28                     ...                                   2.940057   \n",
       "29                     ...                                   6.306159   \n",
       "30                     ...                                   7.011171   \n",
       "31                     ...                                   5.489832   \n",
       "32                     ...                                   2.531524   \n",
       "33                     ...                                   2.082781   \n",
       "34                     ...                                   6.376422   \n",
       "35                     ...                                   4.455009   \n",
       "36                     ...                                   2.938874   \n",
       "37                     ...                                   8.781912   \n",
       "38                     ...                                   4.490428   \n",
       "...                    ...                                        ...   \n",
       "100271722              ...                                   1.857436   \n",
       "100271831              ...                                   2.684300   \n",
       "100271832              ...                                   0.079084   \n",
       "100271835              ...                                   2.434429   \n",
       "100271836              ...                                   2.792174   \n",
       "100271849              ...                                   2.146905   \n",
       "100272146              ...                                   2.220002   \n",
       "100272147              ...                                   5.878317   \n",
       "100272216              ...                                   0.076785   \n",
       "100272217              ...                                   1.590953   \n",
       "100272228              ...                                   2.231822   \n",
       "100286793              ...                                   2.899274   \n",
       "100286844              ...                                   0.905923   \n",
       "100287227              ...                                   0.432181   \n",
       "100287569              ...                                   0.000000   \n",
       "100287704              ...                                   0.000000   \n",
       "100287718              ...                                   0.000000   \n",
       "100288380              ...                                   0.483296   \n",
       "100288778              ...                                   6.593197   \n",
       "100288801              ...                                   0.051291   \n",
       "100289341              ...                                   1.854680   \n",
       "100289635              ...                                   3.453396   \n",
       "100294720              ...                                   0.000000   \n",
       "100302401              ...                                   0.652977   \n",
       "100302640              ...                                   0.019199   \n",
       "100302650              ...                                   1.136914   \n",
       "100302692              ...                                   1.010132   \n",
       "100302736              ...                                   1.570871   \n",
       "100303453              ...                                   0.052402   \n",
       "100303728              ...                                   1.734920   \n",
       "\n",
       "           TCGA-ZF-AA51-01A-21R-A39I-07  TCGA-ZF-AA52-01A-12R-A39I-07  \\\n",
       "ENTREZID                                                                \n",
       "1                              1.944983                      2.372653   \n",
       "2                              8.084193                     10.095678   \n",
       "9                              1.548279                      3.722545   \n",
       "10                             0.000000                      0.138816   \n",
       "12                             1.555709                      3.774938   \n",
       "13                             0.696837                      0.000000   \n",
       "14                             7.154221                      6.930621   \n",
       "15                             0.000000                      0.000000   \n",
       "16                             4.790307                      5.707889   \n",
       "18                             1.746883                      2.499375   \n",
       "19                             2.991613                      2.091500   \n",
       "20                             3.149116                      3.950087   \n",
       "21                             1.113386                      2.348143   \n",
       "22                             3.389721                      3.120593   \n",
       "23                             5.604658                      5.590098   \n",
       "24                             0.300011                      0.421376   \n",
       "25                             3.930508                      4.711956   \n",
       "26                             0.761530                      0.596701   \n",
       "27                             1.888903                      1.985187   \n",
       "28                             0.047274                      0.277321   \n",
       "29                             5.983578                      4.841091   \n",
       "30                             6.898103                      6.407046   \n",
       "31                             4.361208                      4.499776   \n",
       "32                             1.201789                      2.071635   \n",
       "33                             0.051872                      0.023798   \n",
       "34                             4.577791                      3.492034   \n",
       "35                             4.415570                      4.746772   \n",
       "36                             1.959830                      1.615353   \n",
       "37                             8.247836                      8.192882   \n",
       "38                             4.263302                      4.684854   \n",
       "...                                 ...                           ...   \n",
       "100271722                      1.044742                      1.666201   \n",
       "100271831                      2.268963                      4.460098   \n",
       "100271832                      0.000000                      0.000000   \n",
       "100271835                      1.578586                      4.078831   \n",
       "100271836                      1.910625                      1.574269   \n",
       "100271849                      2.099291                      1.335053   \n",
       "100272146                      0.971965                      0.934767   \n",
       "100272147                      3.876211                      4.675443   \n",
       "100272216                      0.211775                      0.113839   \n",
       "100272217                      0.640856                      0.574010   \n",
       "100272228                      0.542195                      1.069636   \n",
       "100286793                      3.363391                      2.931948   \n",
       "100286844                      0.299887                      0.299501   \n",
       "100287227                      0.238998                      0.406512   \n",
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       "100288778                      4.981928                      6.003078   \n",
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       "100289341                      0.509933                      1.492218   \n",
       "100289635                      3.397759                      3.569581   \n",
       "100294720                      0.000000                      0.000000   \n",
       "100302401                      0.249060                      0.581439   \n",
       "100302640                      0.000000                      0.642079   \n",
       "100302650                      1.439982                      2.574464   \n",
       "100302692                      1.275280                      0.552697   \n",
       "100302736                      0.000000                      1.594325   \n",
       "100303453                      0.000000                      0.000000   \n",
       "100303728                      0.570759                      0.795158   \n",
       "\n",
       "           TCGA-ZF-AA53-01A-11R-A39I-07  TCGA-ZF-AA54-01A-11R-A39I-07  \\\n",
       "ENTREZID                                                                \n",
       "1                              3.792826                      3.479011   \n",
       "2                              7.316936                      8.761957   \n",
       "9                              1.132057                      2.568140   \n",
       "10                             0.048032                      0.048921   \n",
       "12                             0.661099                      3.624965   \n",
       "13                             0.000000                      0.186422   \n",
       "14                             6.004271                      7.079890   \n",
       "15                             0.000000                      0.147725   \n",
       "16                             7.424335                      8.709575   \n",
       "18                             0.784887                      1.138534   \n",
       "19                             3.461593                      4.309989   \n",
       "20                             1.512966                      3.063315   \n",
       "21                             0.415792                      1.146891   \n",
       "22                             3.509229                      3.879658   \n",
       "23                             5.312926                      6.285286   \n",
       "24                             1.882620                      0.130356   \n",
       "25                             4.138851                      4.864261   \n",
       "26                             1.438399                      0.121543   \n",
       "27                             2.370396                      3.736276   \n",
       "28                             0.241962                      0.000000   \n",
       "29                             3.985534                      5.395005   \n",
       "30                             6.627765                      4.923261   \n",
       "31                             4.099796                      4.310456   \n",
       "32                             0.923636                      1.525026   \n",
       "33                             0.070492                      0.118533   \n",
       "34                             4.605242                      4.283358   \n",
       "35                             4.056638                      3.347017   \n",
       "36                             0.780055                      2.305503   \n",
       "37                             7.438942                      7.362950   \n",
       "38                             4.018424                      5.138271   \n",
       "...                                 ...                           ...   \n",
       "100271722                      1.198038                      1.466321   \n",
       "100271831                      4.180091                      3.717881   \n",
       "100271832                      0.000000                      0.000000   \n",
       "100271835                      1.537604                      1.442136   \n",
       "100271836                      1.408949                      3.184371   \n",
       "100271849                      1.070452                      2.811217   \n",
       "100272146                      0.105945                      0.529838   \n",
       "100272147                      4.671075                      4.599586   \n",
       "100272216                      0.062768                      1.888743   \n",
       "100272217                      0.210361                      0.445683   \n",
       "100272228                      0.187633                      0.321110   \n",
       "100286793                      3.169480                      3.779393   \n",
       "100286844                      0.202525                      0.316737   \n",
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       "100287569                      0.268763                      1.733056   \n",
       "100287704                      0.000000                      0.000000   \n",
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       "100288778                      5.389232                      5.606450   \n",
       "100288801                      0.000000                      0.000000   \n",
       "100289341                      0.808288                      1.114229   \n",
       "100289635                      2.940335                      3.299210   \n",
       "100294720                      0.091862                      0.000000   \n",
       "100302401                      0.362663                      0.533748   \n",
       "100302640                      0.146898                      2.474504   \n",
       "100302650                      0.854546                      0.781950   \n",
       "100302692                      0.986176                      0.952333   \n",
       "100302736                      2.214244                      2.503191   \n",
       "100303453                      0.000000                      0.066504   \n",
       "100303728                      0.475755                      0.689829   \n",
       "\n",
       "           TCGA-ZF-AA56-01A-31R-A39I-07  TCGA-ZF-AA58-01A-12R-A42T-07  \\\n",
       "ENTREZID                                                                \n",
       "1                              1.405645                      1.572033   \n",
       "2                              8.294718                      7.737907   \n",
       "9                              2.522893                      1.725319   \n",
       "10                             0.229931                      0.000000   \n",
       "12                             4.513976                      4.705967   \n",
       "13                             1.209302                      0.000000   \n",
       "14                             7.159629                      7.005162   \n",
       "15                             0.000000                      0.221314   \n",
       "16                             6.086463                      6.234755   \n",
       "18                             3.009449                      1.090132   \n",
       "19                             3.239834                      2.865977   \n",
       "20                             2.664546                      2.239061   \n",
       "21                             0.973392                      1.574075   \n",
       "22                             3.396367                      4.009166   \n",
       "23                             6.186670                      6.549178   \n",
       "24                             2.567049                      2.568703   \n",
       "25                             4.814331                      4.535544   \n",
       "26                             1.735965                      0.430035   \n",
       "27                             1.990344                      3.346693   \n",
       "28                             2.330907                      0.033785   \n",
       "29                             5.227438                      5.352269   \n",
       "30                             6.389457                      6.324138   \n",
       "31                             5.287507                      3.789480   \n",
       "32                             1.321938                      1.662648   \n",
       "33                             0.513203                      0.000000   \n",
       "34                             4.977100                      4.716416   \n",
       "35                             4.584887                      3.579932   \n",
       "36                             3.151896                      1.116940   \n",
       "37                             7.659910                      7.255310   \n",
       "38                             4.254429                      4.615857   \n",
       "...                                 ...                           ...   \n",
       "100271722                      1.119355                      0.912242   \n",
       "100271831                      2.960833                      3.142854   \n",
       "100271832                      0.076156                      0.000000   \n",
       "100271835                      0.560257                      3.070388   \n",
       "100271836                      2.954052                      1.761250   \n",
       "100271849                      1.928666                      1.942872   \n",
       "100272146                      0.834684                      0.672756   \n",
       "100272147                      4.571879                      5.662731   \n",
       "100272216                      0.543836                      0.491928   \n",
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       "100272228                      0.826413                      0.900913   \n",
       "100286793                      2.941597                      4.904492   \n",
       "100286844                      0.317757                      0.184413   \n",
       "100287227                      0.334906                      0.054436   \n",
       "100287569                      0.158122                      0.487028   \n",
       "100287704                      0.000000                      0.000000   \n",
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       "100288380                      0.130626                      0.177386   \n",
       "100288778                      5.122558                      5.558330   \n",
       "100288801                      0.000000                      0.000000   \n",
       "100289341                      1.576462                      1.462319   \n",
       "100289635                      2.792782                      3.012142   \n",
       "100294720                      0.000000                      0.000000   \n",
       "100302401                      0.387988                      0.907954   \n",
       "100302640                      0.000000                      0.969502   \n",
       "100302650                      1.542125                      0.491698   \n",
       "100302692                      0.542730                      0.421700   \n",
       "100302736                      1.636781                      0.250190   \n",
       "100303453                      0.000000                      0.000000   \n",
       "100303728                      0.709897                      0.812898   \n",
       "\n",
       "           TCGA-ZF-AA5H-01A-11R-A39I-07  TCGA-ZF-AA5N-01A-11R-A42T-07  \\\n",
       "ENTREZID                                                                \n",
       "1                              0.802134                      0.420320   \n",
       "2                              7.179355                      4.904007   \n",
       "9                              1.461496                      1.847315   \n",
       "10                             0.029659                      0.000000   \n",
       "12                             1.681905                      3.356545   \n",
       "13                             0.000000                      0.000000   \n",
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       "23                             6.333991                      5.442255   \n",
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       "...                                 ...                           ...   \n",
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       "100303728                      0.446765                      0.257565   \n",
       "\n",
       "           TCGA-ZF-AA5P-01A-11R-A39I-07  \n",
       "ENTREZID                                 \n",
       "1                              1.271811  \n",
       "2                             11.189585  \n",
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       "38                             5.106815  \n",
       "...                                 ...  \n",
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       "\n",
       "[20531 rows x 427 columns]"
      ]
     },
     "execution_count": 14,
     "metadata": {},
     "output_type": "execute_result"
    }
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  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {},
   "outputs": [],
   "source": []
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