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+Package: HuMMuS
+Title: Heterogeneous Multilayer Network for Multi-Omics Single-Cell Data
+Version: 0.0.2
+Authors@R: person(given = "Rémi",
+    family = "Trimbour",
+    email = "remi.trimbour@pasteur.fr",
+    role = c("aut", "cre"),
+    comment = c(ORCID = "0000-0001-8770-8412"))
+Description: A general framework to infer regulatory mechanisms from multi-omics single-cell data.
+    HuMMuS package provides functions to build individual networks
+    from different single-cell modalities, then to integrate them
+    into a single-cell heterogeneous multilayer network. The package
+    also provides functions to infer regulatory mechanisms from the
+    heterogeneous multilayer network.
+    HuMMuS is based on a flexible framework that can be adapted to any
+    single-cell modalities. We provide study cases for scRNA+scATAC
+    and scRNA+scATAC+snmC(methylation) that can be completed by PPI.
+    Many regulatory mechanisms can be inferred with HuMMuS, notably
+    classical gene regulatory networks (GRN), but TF-target genes,
+    enhancer-gene interactions, TF-enhancer bindings, or even research
+    of heterogeneous communnities of omics features (e.g. ensemble of
+    peaks, genes and TFs cooperating to the same biological function).
+License: AGPL (>= 3)
+Encoding: UTF-8
+LazyData: true
+Roxygen: list(markdown = TRUE)
+RoxygenNote: 7.2.3
+Depends:
+    R (>= 4.0.0)
+biocViews:
+Imports:
+    grr,
+    sparseMatrixStats,
+    TFBSTools,
+    stringr,
+    JASPAR2020,
+    chromVAR,
+    IRanges,
+    Matrix,
+    S4Vectors,
+    utils,
+    tidyr,
+    OmnipathR,
+    GENIE3,
+    reshape2,
+    Signac,
+    biovizBase,
+    SingleCellExperiment,
+    motifmatchr,
+    reticulate
+Suggests:
+    doParallel,
+    doRNG,
+    EnsDb.Hsapiens.v86,
+    BSgenome.Hsapiens.UCSC.hg38,
+    knitr,
+    rmarkdown
+VignetteBuilder: knitr
+URL: https://cantinilab.github.io/HuMMuS/