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--- a +++ b/R-scripts/data/bio_annotations/c2.cp.reactome.v6.2.symbols.gmt @@ -0,0 +1,674 @@ +REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS AGL GYG1 PGM1 PHKA1 PHKA2 PHKB PHKG1 PHKG2 PGM2 PYGB PYGL PYGM PHKA1P1 LOC650556 CALM1 CALM2 CALM3 GYG2 +REACTOME_TRANSLATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSLATION SEC61B RPL35 EEF1DP1 RPL7AP27 DDOST EEF1A1 EEF1B2 EEF1D EEF1G EEF2 EIF1AX EIF2S1 EIF2B1 EIF2S3 EIF4A1 EIF4A2 EIF4B EIF4E EIF4EBP1 EIF4G1 EIF5 ETF1 FAU TRAM1 SEC11A SEC61G RPL13A GSPT2 RPL36 PABPC1 EIF3K RPL10P16 FAM153A SPCS1 SEC61A1 EIF3FP3 RPL36P14 EIF3E RPSAP12 RPS8P10 RPL7AP66 RPL10P9 RPS12P4 RPSA RPS26P10 RPL23AP2 RPS12P22 RPL21P29 RPS26P35 RPL10A RPL26L1 SEC61A2 SRPRB SPCS3 RPL3 RPL3L RPL4 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL10 RPL11 RPL12 RPL13 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL23A RPL24 RPL26 RPL27 RPL30 RPL27A RPL28 RPL29 RPL31 RPL32 RPL34 RPL35A RPL37 RPL37A RPL38 RPL39 RPL41 RPL36A RPLP0 RPLP1 RPLP2 RPN1 RPN2 RPS2 RPS3 RPS3A RPS4X RPS4Y1 RPS5 RPS6 RPS7 RPS8 RPS9 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS18 RPS19 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS28 RPS29 RPL6P19 LOC647030 LOC641895 RPL36AP31 RPS29P3 RPS26P28 RPL36AP8 RPL26P22 RPS26P20 RPS15AP11 RPS26P50 RPL22P11 RPL17P6 RPS13P8 RPS28P4 RPL32P16 LOC646184 RPS28P7 RPL12P2 LOC647074 RPL23AP42 RPL5P1 RPL36AP51 LOC649602 LOC650638 RPS28P9 RPL34P27 LOC651825 LOC651894 LOC652607 RPL26P30 RPSAP9 SRP9P1 RPL19P9 LOC653566 RPL21P119 RPL31P17 LOC653881 LOC653994 SRP9 SRP14 SRP19 SRP54 SRP68 SRP72 SRPR SSR1 SSR2 SSR3 SSR4 RPL31P31 RPL15P17 RPL23AP18 RPL26P24 RPL21P75 RPS27AP11 RPS26P7 RPL21P134 RPS26P25 RPS19P3 RPL36AP23 RPS18P10 RPL17P36 RPL36AP37 RPL21P16 RPL23AP74 RPS15P5 RPL23AP63 LOC729998 RPS10P9 LOC730343 RPS18P5 UBA52 RPL34P31 EIF4H EIF3A EIF3B EIF3C EIF3D EIF3F EIF3G EIF3H EIF3I EIF3J EIF2B4 EIF2B3 EIF2B2 EIF2B5 EIF2S2 RPL14 SEC11C RPL23 EIF5B SPCS2 +REACTOME_PYRIMIDINE_CATABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PYRIMIDINE_CATABOLISM UPP2 DPYD DPYS TYMP NT5C NT5E NT5C3 UPB1 NT5M AGXT2 UPP1 NT5C1A +REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER POLR3F POLR3C POLR3A LZTS1 POLR3H BRF1 GTF3C2 POLR1D POLR3K POLR2E POLR2F POLR2H POLR2K POLR2L POLR3B POLR3E POLR3D TBP POLR3GL GTF3C5 GTF3C4 GTF3C3 POLR1C +REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS ANAPC10 UBE2C CDC26 ANAPC2 ANAPC4 MAD2L1 ANAPC5 ANAPC7 ANAPC11 ANAPC1 LOC647654 LOC649620 LOC650621 LOC651763 BUB1B CDC26P1 LOC730594 UBE2D1 UBE2E1 CDC23 CDC16 BUB3 CDC20 CDC27 +REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE ADHFE1 CS DLAT DLD DLST FH NNT SLC16A8 LOC283398 IDH1 IDH2 IDH3A IDH3B IDH3G LDHA LDHB MDH2 OGDH ACO2 PDHA1 PDHB PDK1 PDK2 PDK3 PDK4 PDP1 PDPR PDP2 SDHA SDHB SDHC SDHD SUCLA2P1 LOC646675 LOC646677 LOC650667 LOC650674 LOC650883 LOC651820 SLC16A1 BSG D2HGDH L2HGDH PDHX SUCLG2 SUCLG1 SUCLA2 SLC16A3 +REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS FAS FASLG TNF TNFRSF1A TRAF2 CASP8 CASP10 TRADD RIPK1 TNFSF10 FADD TNFRSF10B CFLAR +REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION ARSK DHPS EIF5A F2 F7 F9 F10 ARSG SUMF2 GGCX SUMF1 ARSI ARSH ARSA ARSB STS ARSE ARSF FURIN PROC PROS1 EIF5A2 LOC652612 VKORC1 ARSJ DOHH PROZ +REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS BCAP31 ADD1 CTNNB1 DSG1 DSG2 DSG3 DSP ACIN1 FNTA GAS2 DBNL GSN APC BIRC2 LMNA LMNB1 MAPT OCLN MST4 PKP1 PLEC PRKCD PRKCQ PTK2 ROCK1 SATB1 LOC647859 LOC652460 BMX SPTAN1 TJP1 ROCK1P1 VIM CASP3 CASP6 CASP7 CASP8 STK24 TJP2 CDH1 +REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION CDK7 ERCC2 ERCC3 POLR1A PTRF GTF2H1 GTF2H2 GTF2H3 GTF2H4 MNAT1 POLR1D POLR2H POLR2K LOC652857 GTF2H2B UBTF POLR1B TAF1C TAF1B TAF1A CCNH POLR1C +REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX EIF1AX EIF2S1 EIF2S3 FAU EIF3K EIF3FP3 EIF3E RPSAP12 RPS8P10 RPS12P4 RPSA RPS26P10 RPS12P22 RPS26P35 RPS2 RPS3 RPS3A RPS4X RPS4Y1 RPS5 RPS6 RPS7 RPS8 RPS9 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS18 RPS19 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS28 RPS29 RPS29P3 RPS26P28 RPS26P20 RPS15AP11 RPS26P50 RPS13P8 RPS28P4 RPS28P7 RPS28P9 LOC651894 RPSAP9 RPS27AP11 RPS26P7 RPS26P25 RPS19P3 RPS18P10 RPS15P5 RPS10P9 RPS18P5 EIF3A EIF3B EIF3C EIF3D EIF3F EIF3G EIF3H EIF3I EIF3J EIF2S2 +REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX CDK2 DBF4 ORC6 ORC3 POLA2 RPA4 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 ORC1 ORC2 ORC4 ORC5 POLA1 POLE POLE2 MCM10 PRIM1 PRIM2 RPA1 RPA2 RPA3 LOC645084 CDT1 CDC7 CDC45 MCM8 CDC6 +REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS PAPOLA CLP1 NUDT21 CSTF1 CSTF2 CSTF3 NCBP2 CPSF1 NCBP1 PCF11 CPSF3 CPSF2 CPSF7 PABPN1 +REACTOME_GAP_JUNCTION_DEGRADATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GAP_JUNCTION_DEGRADATION AP2M1 CLTA CLTB CLTC DAB2 DNM1 DNM2 GJA1 MYO6 CLTCL1 +REACTOME_BASE_EXCISION_REPAIR http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BASE_EXCISION_REPAIR CCNO POLD3 FEN1 SMUG1 APEX1 LIG1 LIG3 MPG MUTYH NTHL1 OGG1 PCNA POLB POLD1 POLD2 POLD4 TDG XRCC1 MBD4 +REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM ACOT8 SLCO1B1 CYP46A1 SLC27A5 SLC27A2 AKR1C4 CYP7A1 CYP8B1 CYP27A1 ALB FABP6 AMACR SLCO1B3 HSD17B4 CYP39A1 BAAT SCP2 SLC10A1 SLC10A2 SLCO1A2 AKR1D1 HSD3B7 ACOX2 ABCB11 ABCC3 CH25H CYP7B1 +REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL ACOT8 SLC27A5 SLC27A2 AKR1C4 CYP7A1 CYP8B1 CYP27A1 AMACR HSD17B4 BAAT SCP2 AKR1D1 HSD3B7 ACOX2 ABCB11 +REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS SLCO1B1 SLC27A5 ALB FABP6 SLCO1B3 BAAT SLC10A1 SLC10A2 SLCO1A2 ABCB11 ABCC3 +REACTOME_SIGNALING_BY_RHO_GTPASES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_RHO_GTPASES FAM13A NET1 DLC1 VAV3 RALBP1 AKAP13 CHN1 CHN2 ARAP2 ARAP1 TAGAP FGD4 ARHGAP36 RHOV ECT2 A2M FGD2 FGD1 ARHGAP26 RHOBTB2 ARHGEF9 ARHGEF12 ARHGEF18 SRGAP2 RHOQ HMHA1 ARHGAP8 ARHGAP30 NGEF TIAM2 GDI1 GDI2 ARHGEF16 ABR ARHGAP35 RACGAP1 RHOD ARHGAP40 RHOA RHOB RHOC RHOG ARHGAP1 ARHGAP4 ARHGAP6 ARHGDIA ARHGDIB ARHGDIG RHOH MCF2 MYO9B OCRL OPHN1 ARHGEF4 ARHGEF3 GMIP FAM13B PIK3R2 RHOF ARHGAP17 RHOT1 PRR5-ARHGAP8 DEPDC1B ARHGAP15 RHOJ ARHGAP31 SRGAP1 ARHGAP20 PREX1 ARHGAP22 RAC1 RAC2 RAC3 RASGRF1 RASGRF2 BCR ARAP3 ITSN1 PLEKHG2 SOS1 SOS2 TIAM1 TRIO LOC732425 VAV1 ARHGAP10 ARHGAP28 ARHGAP24 OBSCN SYDE2 ARHGAP19 SYDE1 ARHGAP11B FGD3 RHOT2 KALRN STARD13 DEPDC7 ARHGEF2 ARHGAP18 ARHGAP29 ARHGAP12 ARHGEF6 STARD8 ARHGAP11A ARHGEF11 ARHGEF17 RHOBTB1 SRGAP3 G3BP2 ARHGAP44 ARHGAP25 CDC42 +REACTOME_SIGNALING_BY_WNT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_WNT FRAT1 PSMD14 FAM123B PSMA8 CSNK1A1 CTNNB1 PSME4 FRAT2 APC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RPS27A SKP1 LOC652826 RPS27AP11 UBA52 AXIN1 CUL1 BTRC PSMF1 PSMD6 +REACTOME_METABOLISM_OF_NON_CODING_RNA http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_NON_CODING_RNA SNUPN PRMT5 NUP50 NUPL2 DDX20 SNRPD2P1 CLNS1A NUP35 NCBP2 NUP205 NUP210 NUP188 NUP62 GEMIN5 NUP43 NCBP1 NUP88 GEMIN4 PHAX NUP54 NUP133 NUP107 RANBP2 SMN1 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG TPR NUP37 WDR77 GEMIN7 GEMIN6 NUP85 NUP214 AAAS SEH1L RAE1 GEMIN2 NUP155 TGS1 NUP93 NUPL1 POM121 NUP153 +REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL CYP46A1 SLC27A5 SLC27A2 AKR1C4 CYP8B1 CYP27A1 AMACR CYP39A1 AKR1D1 HSD3B7 +REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS ACOT8 CYP46A1 SLC27A5 SLC27A2 AKR1C4 CYP7A1 CYP8B1 CYP27A1 AMACR HSD17B4 CYP39A1 BAAT SCP2 AKR1D1 HSD3B7 ACOX2 ABCB11 CH25H CYP7B1 +REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D CGA CYP2R1 CLPS STARD4 STARD6 CYP11A1 CYP11B1 CYP11B2 CYP17A1 CYP19A1 CYP21A2 CYP24A1 CYP27B1 AKR1B1 GC HSD3B1 HSD3B2 HSD11B1 HSD17B1 HSD17B3 LHB LRP2 RDH11 BCMO1 PNLIP POMC LGMN RBP2 SRD5A1 SRD5A2 STAR SRD5A3 CUBN STARD5 LRAT +REACTOME_ANDROGEN_BIOSYNTHESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ANDROGEN_BIOSYNTHESIS CGA CYP17A1 HSD3B1 HSD3B2 HSD17B3 LHB POMC SRD5A1 SRD5A2 SRD5A3 +REACTOME_SIGNALLING_BY_NGF http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALLING_BY_NGF AKT3 BCL2L11 DNAL4 CDKN1A CDKN1B NET1 VAV3 ADCY1 ADCY2 FRS2 ADCY3 ADCY5 PRDM4 ADCY6 AKAP13 ADCY7 ADCY8 CHUK ADCY9 ADCYAP1 ADCYAP1R1 THEM4 AP2M1 AP2S1 CLTA CLTC FGD4 ADORA2A CREB1 CRK MAPK14 ADRBK1 AP2A1 AP2A2 AP2B1 DNM1 DNM2 DUSP3 DUSP4 DUSP6 DUSP7 ECT2 ADCY4 ELK1 AKT1 AKT2 FGD2 FGD1 SORCS3 FOXO1 FOXO3 ARHGEF9 PHLPP1 ARHGEF12 ARHGEF18 NCSTN ITGB3BP MTOR RICTOR SHC2 NGEF TIAM2 AATF NGFRAP1 ARHGEF16 GRB2 RAPGEF1 ABR GSK3A HDAC1 HDAC2 NR4A1 HRAS IKBKB IRAK1 IRS1 ITPR2 ITPR3 KRAS RHOA ARHGAP4 ARHGDIA MAG MCF2 MDM2 MEF2A MEF2C FOXO4 LOC440917 MYD88 ATF1 NFKBIA NGF NGFR NRAS NTRK1 NTRK2 OMG FURIN PCSK6 ARHGEF4 ARHGEF3 APH1A PCSK5 PDE1A PDE1B PDPK1 PIK3CA PIK3CB PIK3R1 PIK3R2 PLCG1 SHC3 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCD PRKCE PRKCG PRKCI PSENEN MAPK1 MAPK3 MAPK7 MAPK8 MAPK11 MAPK13 MAP2K1 MAP2K2 MAP2K5 PSEN1 PSEN2 RTN4 BAD PTEN KIDINS220 PREX1 TRIB3 RAC1 RAF1 RALA RALB RALGDS RAP1A RASGRF1 RASGRF2 RELA RIT2 RIT1 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KB2 RPS27A MAPK12 MLST8 ITSN1 SH3GL2 SHC1 PLEKHG2 SMPD2 SOS1 SOS2 SRC BRAF STAT3 ADAM17 TIAM1 TRAF6 TRIO TSC2 RPS27AP11 LOC729120 LOC730418 UBA52 LOC731292 VAV1 YWHAB YWHAE MAPKAPK3 MAPKAP1 CALM1 CALM2 CALM3 CAMK4 APH1B CASP2 CASP3 OBSCN CASP9 AKT1S1 LINGO1 IRS2 RIPK2 HDAC3 SQSTM1 FGD3 KALRN ARHGEF1 ARHGEF2 RPS6KA5 MAPKAPK2 ARHGEF6 MAGED1 ARHGEF11 ARHGEF17 CDK1 +REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE FRAT1 FAM123B CSNK1A1 CTNNB1 FRAT2 APC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E AXIN1 +REACTOME_INSULIN_RECEPTOR_RECYCLING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INSULIN_RECEPTOR_RECYCLING TCIRG1 ATP6V1G3 ATP6V0A2 ATP6V0D2 ATP6V1C2 INS INSR ATP6V0A4 ATP6V1D ATP6V1H ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V0C ATP6V1C1 ATP6V1E1 ATP6V0B ATP6V1G2 ATP6V0E1 ATP6V1E2 ATP6V0D1 ATP6V1F ATP6V1G1 +REACTOME_COPI_MEDIATED_TRANSPORT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_COPI_MEDIATED_TRANSPORT COPE COPA COPB1 COPZ1 COPG ARCN1 ARF1 ARFGAP1 GBF1 COPB2 +REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION AP1M2 AP1S1 AP1B1 AP1G1 HLA-A PACS1 B2M HLA-K AP1S2 AP1M1 +REACTOME_SIGNALING_BY_SCF_KIT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_SCF_KIT AKT3 SH2B3 CDKN1A CDKN1B SH2B2 GRAP CHEK1 CHUK THEM4 CMA1 CREB1 AKT1 AKT2 FER FES FOXO1 FOXO3 PHLPP1 MTOR RICTOR FYN GRB2 GRB7 GRB10 GSK3A NR4A1 HRAS JAK2 KIT KRAS LCK LYN MDM2 KITLG FOXO4 MMP9 NRAS PDPK1 PIK3CA PIK3R1 PIK3R2 PRKCA MAPK1 MAPK3 MAP2K1 MAP2K2 BAD PTEN TRIB3 PTPN6 RAC1 RAF1 RPS6KB2 MLST8 LOC653882 SOS1 SRC STAT1 STAT3 STAT5A STAT5B TEC TSC2 LOC729120 LOC731292 VAV1 YES1 YWHAB MAPKAP1 CASP9 AKT1S1 PIK3R3 SOCS1 CBL SOCS6 GRAP2 CDK1 GAB2 +REACTOME_DEVELOPMENTAL_BIOLOGY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DEVELOPMENTAL_BIOLOGY CDH2 AKT3 MED6 CDH4 MED16 RANBP9 CDH15 PLXNC1 CDK4 CDK5 CDK8 PAK4 SEMA3A MYL12B MYL9 CAP2 CAP1 NCOA2 SEMA4D CEBPB CEBPD DPYSL4 DRAP1 LEFTY1 CFL1 PPARGC1A STIP1 MED8 AP2M1 AP2S1 CLTA CLTC CNTN1 COL1A1 COL1A2 COL2A1 COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL5A1 COL5A2 COL6A1 COL6A2 COL6A3 COL9A1 COL9A2 COL9A3 ACVR1C UNC5D CREB1 CREBBP CRMP1 MAPK14 CSNK2A1 CSNK2A2 CSNK2B NCAN HFE2 CTNNA1 CTNNB1 AP2A1 AP2A2 AP2B1 DCC DCX DLG1 DLG3 DNM1 DNM2 DOCK1 DPYSL2 DPYSL3 EBF1 EGFR EGR2 EP300 ERBB2 AKT1 AKT2 ALCAM FABP4 MED19 UNC5B FES FGF10 FGFR1 ABLIM3 NCOA6 FOXO1 FOXO3 CDK19 PLXND1 CLASP1 ARHGEF12 SRGAP2 MED13L PIP5K1C KIF4A NR5A2 ABL1 FYN PTF1A GCK GDF1 GDNF GFRA1 GFRA2 ABL2 CNTN6 RND1 RPS6KA6 GPC1 LAMA1 KIF4B RGMB ANK1 ANK3 GRB2 MED4 ARHGAP35 FOXA2 FOXA3 HNF4A HNF4G ONECUT1 HRAS HES1 HSP90AA1 HSP90AB1 IAPP RBPJ INS INSM1 PDX1 ITGA1 ITGA2 ITGA2B ITGA5 ITGA9 ITGAV ITGB1 ITGB3 AGRN KCNQ2 KCNQ3 KRAS RHOA RHOB RHOC MAFA L1CAM ONECUT3 RHOG LAMB1 LAMC1 LEP ABLIM1 LIMK1 LIMK2 MED11 LPL SMAD2 SMAD3 SMAD4 MEF2A MEF2BNB-MEF2B MEF2C MEF2D MET MSN MYF5 MYF6 MYH9 MYH10 MYH11 MYL6 MYO10 MYOD1 MYOG NCAM1 NCK1 NEO1 NEUROD1 NKX2-2 NKX6-1 NODAL NRAS NRCAM NRTN NTN3 FURIN PCSK6 PAK1 PAK2 NEUROG3 PAX6 CDON MED31 PCK1 ANGPTL4 SPTBN5 EVL MED15 PFN1 PFN2 PITPNA PKLR PLCG1 PLIN1 PLXNA1 PLXNA2 PLXNB1 PLXNB3 TREM2 PPARA PPARG MED1 MED18 MED9 PLXNA3 MED29 ENAH SCN3B PRKCQ MAPK1 MAPK3 MAPK11 MAP2K1 MAP2K2 MAP2K6 PRNP PSPN DPYSL5 PAK6 RGMA TRPC7 PAK7 PTK2 SRGAP1 SEMA6A KIAA1598 SPTBN4 PTPRC RAC1 RAC2 RAF1 NTN4 RDX RELA ROBO1 ROBO2 ROCK1 RPS6KA1 RPS6KA2 RPS6KA3 RRAS RXRA MAPK12 SCN1B SCN2A SCN2B SCN4A SCN5A SCN7A SCN8A SDCBP GFRA4 MYL8P LOC642076 SEMA4A ROBO3 LOC644816 SH3GL2 SIAH1 SIAH2 LOC650400 SLC2A2 SLC2A4 SLIT1 SLIT3 SMARCD3 BNIP2 SOS1 SOS2 SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SRC SREBF1 MED22 KLF5 CNTN2 TBL1X TCF4 HNF1A HNF1B TCF3 TCF12 TDGF1 NR2F2 TGFB1 LEFTY2 TLN1 TNF TRIO TRPC3 TRPC4 TRPC5 TRPC6 ROCK1P1 LOC729030 MEF2BNB LOC730030 LOC730221 LOC730335 TYROBP LOC731231 VASP EZR WNT1 WNT10B YWHAB CACNA1S CACNB1 CACNB2 CACNB3 CACNB4 ST8SIA4 TBL1XR1 MYH14 SEMA6D ST8SIA2 MED25 NCOA3 MED10 NCK2 SEMA7A CNTNAP1 PRIC285 UNC5C NCOA1 NUMB NRP2 NRP1 HDAC3 CDK5R1 CACNA1I CACNA1H CACNA1G CCNC FOXH1 CCND3 WASL RPS6KA4 UNC5A SEMA5A MED30 ARTN ACVR1B BOC ACVR2A RPS6KA5 MED14 ACVR2B KLF4 CD24 CER1 SLIT2 ADIPOQ MED21 NTN1 MED23 MED17 MED26 MED27 MED7 ROCK2 MED20 CD36 NCOR1 NCOR2 TGS1 CD72 SEMA3E ARHGEF11 CDK1 FARP2 MED24 SRGAP3 MED12 CDC42 +REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES PSMD14 PSMA8 FCGR1A FCGR1B PSME4 MRC1 CD207 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 LOC652826 PSMF1 PSMD6 MRC2 +REACTOME_SIGNALING_BY_NODAL http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_NODAL DRAP1 LEFTY1 ACVR1C FOXO3 GDF1 SMAD2 SMAD3 SMAD4 NODAL FURIN PCSK6 TDGF1 LEFTY2 FOXH1 ACVR1B ACVR2A ACVR2B CER1 +REACTOME_DAG_AND_IP3_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DAG_AND_IP3_SIGNALING ADCY1 ADCY2 ADCY3 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 CREB1 ADRBK1 ADCY4 ITPR2 ITPR3 PDE1A PDE1B PLCG1 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCD PRKCE PRKCG LOC730418 CALM1 CALM2 CALM3 CAMK4 +REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING SPRY2 GRB2 PPP2CA PPP2CB PPP2R1A MAPK1 MAPK3 RPS27A SRC BRAF RPS27AP11 UBA52 MKNK1 CBL +REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT ATP5H ATP5L UQCR11 NDUFA11 COX4I1 COX5B COX6A1 COX6B1 COX6C COX7B COX7C COX8A ADHFE1 CS CYC1 DLAT DLD DLST ETFA ETFB ETFDH FH NNT SLC16A8 UQCRQ LOC283398 IDH1 IDH2 IDH3A IDH3B IDH3G NDUFS7 LDHA LDHB MDH2 UQCRHL ATP6 ATP8 COX1 COX2 COX3 CYTB ND1 ND2 ND3 ND4 ND4L ND5 ND6 NDUFA1 NDUFA2 NDUFA3 NDUFA4 NDUFA5 NDUFA6 NDUFA7 NDUFA8 NDUFA9 NDUFA10 NDUFAB1 NDUFB1 NDUFB2 NDUFB3 NDUFB4 NDUFB5 NDUFB6 NDUFB7 NDUFB8 NDUFB9 NDUFB10 NDUFC1 NDUFC2 NDUFS1 NDUFS2 NDUFS3 NDUFV1 NDUFS4 NDUFS5 NDUFS6 NDUFS8 NDUFV2 NDUFV3 OGDH ATP5A1 ACO2 ATP5B ATP5C1 NDUFA13 ATP5D ATP5E ATP5F1 ATP5G1 PDHA1 PDHB PDK1 PDK2 PDK3 PDK4 ATP5I ATP5J ATP5O CYCS PDP1 PDPR NDUFA12 PDP2 SDHA SDHB SDHC SDHD LOC642727 MTND5P10 UQCRBP1 SUCLA2P1 LOC646675 LOC646677 LOC650667 LOC650674 LOC650883 LOC651820 SLC16A1 BSG LOC727947 D2HGDH UCP1 UCP2 UCP3 UQCRB UQCRC1 UQCRC2 UQCRFS1 UQCRH L2HGDH PDHX SUCLG2 SUCLG1 SUCLA2 SLC16A3 COX7A2L COX5A ATP5J2 +REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION NAMPT NCOA2 PPARGC1A CREBBP CRY1 CRY2 DBP EP300 F7 NCOA6 CCRN4L NR3C1 ARNTL NPAS2 SERPINE1 PER1 PPARA MED1 AVP ARNTL2 RORA RXRA SMARCD3 TBL1X BHLHE41 TBL1XR1 NCOA3 PRIC285 BHLHE40 NCOA1 HDAC3 PER2 NR1D1 CLOCK NCOR1 TGS1 +REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION PSMD14 SEC61B PSMA8 CTSS CYBA CYBB FCGR1A FCGR1B PSME4 SEC61G PDIA3 SEC61A1 HLA-A HLA-B HLA-C HLA-F HLA-G ITGAV ITGB5 LNPEP MRC1 NCF2 NCF4 CD207 SEC61A2 B2M PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RPS27A LOC648998 HLA-K LOC652826 TAP1 TAP2 RPS27AP11 UBA52 CALR CD36 PSMF1 PSMD6 MRC2 +REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING CISH CSH1 SH2B1 GH1 GH2 GHR IRS1 JAK2 LYN MAPK1 MAPK3 PRL PRLR PTPN1 PTPN6 STAT1 STAT3 STAT5A STAT5B ADAM17 SOCS1 IRS2 SOCS2 SOCS3 +REACTOME_TRIF_MEDIATED_TLR3_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRIF_MEDIATED_TLR3_SIGNALING NOD1 TAB1 RIPK3 CHUK CREB1 ATF2 MAPK14 TICAM1 AGER DUSP3 DUSP4 DUSP6 DUSP7 ELK1 TAB2 FOS TAB3 TBK1 HMGB1 APP IKBKB IRAK1 IRAK2 IRF3 IRF7 JUN MEF2A MEF2C ATF1 NFKB2 NFKBIA NFKBIB PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D MAPK1 MAPK3 MAPK7 MAPK8 MAPK11 MAPK9 MAPK10 MAP2K1 MAP2K2 MAP2K3 MAP2K6 MAP2K7 RELA RPS6KA1 RPS6KA2 RPS6KA3 RPS27A S100A12 S100B SAA1 NOD2 MAP2K4 LOC650832 MAP3K7 TLR3 TRAF6 RPS27AP11 UBA52 MAPKAPK3 ZBP1 IKBKG RIPK1 RIPK2 RPS6KA5 MAPKAPK2 IKBKE CDK1 +REACTOME_CELL_CELL_COMMUNICATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_CELL_COMMUNICATION CDH2 CDH3 CDH4 CDH5 CDH6 CDH7 CDH8 CDH9 CDH10 CDH11 CDH12 CDH13 CDH15 CDH18 INADL SIRPB1 CLDN16 FERMT2 COL17A1 CLDN4 CLDN3 CLDN7 SIRPA MAPK14 CLDN19 CTNNA1 CTNNB1 CTNND1 DCC DSCAM PTK2B FLNC CLDN14 CD2AP CADM1 CLDN15 FYB FYN CADM2 PVRL3 CLDN17 GRB2 PARVB ILK ITGB1 ITGB4 JUP LAMA3 LAMB3 LAMC2 LIMS1 NCK1 NPHS1 CLDN20 CLDN11 PAK1 F11R PARD6A CLDN18 PIK3CA PIK3CB PIK3R1 PIK3R2 PLEC CLDN22 FBLIM1 SIRPG PARVA PRKCI MAPK8 MAPK11 MAPK13 PARD3 DSCAML1 PTK2 PTPN6 PVR PVRL1 PVRL2 RAC1 RSU1 MAPK12 MPP5 CDH24 LOC652460 SPTAN1 SPTBN1 SRC TESK1 CLDN5 LOC729030 LIMS3 TYROBP VASP ACTN4 PVRL4 KIRREL2 NCK2 PARD6G PARD6B KIRREL3 ACTN1 ACTN2 IQGAP1 SKAP2 WASL CLDN12 CLDN10 CLDN8 CLDN6 CLDN2 CLDN1 CLDN9 CRB3 NTN1 ARHGEF6 CD47 CD151 MAGI2 CDH1 +REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS ABCA7 ABCA10 ABCA9 ABCA2 ABCA3 ABCD1 ABCD2 ABCA6 ABCA12 APOA1 PEX19 ABCD3 ABCG4 ABCG5 ABCG8 ABCD1P5 PEX3 ABCG1 +REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY CTSS HLA-A HLA-B HLA-C HLA-F HLA-G LNPEP B2M HLA-K +REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION DHFR AKT1 GCH1 GCHFR HSP90AA1 NOS3 PRKG2 PTS DHFRP1 SPR CALM1 CALM2 CALM3 +REACTOME_ER_PHAGOSOME_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ER_PHAGOSOME_PATHWAY PSMD14 SEC61B PSMA8 PSME4 SEC61G PDIA3 SEC61A1 HLA-A HLA-B HLA-C HLA-F HLA-G SEC61A2 B2M PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RPS27A HLA-K LOC652826 TAP1 TAP2 RPS27AP11 UBA52 CALR PSMF1 PSMD6 +REACTOME_MEIOSIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MEIOSIS RAD50 CDK2 CDK4 STAG1 SYCP2 STAG3 STAG2 DIDO1 DMC1 HIST4H4 HIST2H3C HIST3H2BB SYNE2 SYNE1 SPO11 HIST1H2BA SUN2 POT1 TINF2 MLH3 SMC1B HIST1H2AE HIST1H2AD H2AFX H2AFZ HIST1H2BD HIST1H2BB H3F3A H3F3B HSPA2 HIST2H3A H3F3AP5 LMNA LMNB1 MLH1 MRE11A MSH4 MSH5 NBN ATM SYCP3 TERF2IP ATR HIST2H4B TEX15 TEX12 PRDM9 RAD21 RAD51 RAD51C RBBP8 RPA1 RPA2 RPA3 BLM H3F3AP6 LOC648152 ACD LOC651610 LOC651921 HIST2H3D BRCA1 BRCA2 SYCP1 TERF1 TERF2 TOP3A HIST2H2AA4 LOC731820 UBE2I SMC1A HIST3H3 HIST1H4I HIST1H2AJ HIST1H2AC HIST1H2AB HIST2H2AA3 HIST2H2AC HIST1H2BG HIST1H2BL HIST1H2BN HIST1H2BM HIST1H2BF HIST1H2BE HIST1H2BH HIST1H2BI HIST1H2BC HIST1H2BO HIST2H2BE HIST1H3A HIST1H3D HIST1H3C HIST1H3E HIST1H3I HIST1H3G HIST1H3J HIST1H3H HIST1H3B HIST1H4A HIST1H4D HIST1H4F HIST1H4K HIST1H4J HIST1H4C HIST1H4H HIST1H4B HIST1H4E HIST1H4L HIST2H4A MND1 FKBP6 HIST1H2BK HIST1H3F HIST1H2BJ SMC3 REC8 +REACTOME_NEGATIVE_REGULATION_OF_FGFR_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEGATIVE_REGULATION_OF_FGFR_SIGNALING SPRY2 FRS2 KLB FGF1 FGF2 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGF10 FGFR1 FGFR3 FGFR2 FGFR4 FGF20 FGF22 GRB2 PPP2CA PPP2CB PPP2R1A MAPK1 MAPK3 RPS27A SRC BRAF RPS27AP11 UBA52 FGF23 MKNK1 CBL FGF18 FGF17 KL FGF19 +REACTOME_G0_AND_EARLY_G1 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G0_AND_EARLY_G1 CDK2 LIN54 DYRK1A E2F1 E2F4 E2F5 LIN9 HDAC1 LOC441488 MYBL2 PCNA LIN37 RBBP4 RBL1 RBL2 RBBP4P1 TFDP1 CCNA2 CCNA1 CCNE1 CCNE2 LIN52 CDK1 CDC6 CDC25A +REACTOME_REGULATION_OF_KIT_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_KIT_SIGNALING SH2B3 SH2B2 FYN GRB2 KIT LCK LYN KITLG PRKCA PTPN6 LOC653882 SOS1 SRC YES1 SOCS1 CBL SOCS6 +REACTOME_MEMBRANE_TRAFFICKING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MEMBRANE_TRAFFICKING GJC1 AP1M2 PREB STAM2 SEC24B SEC23A TGOLN2 AP4B1 GJB6 SNF8 COPE AP2M1 AP1S1 AP3S1 CLTA CLTB CLTC GJB4 CHMP4B COPA COPB1 CPD VPS37A CTSZ SH3D19 VPS37D DAB2 AP1B1 AP1G1 DNM1 DNASE2 DNM2 GJD4 COPZ1 COPG SEC31A AP4E1 SNAPIN FTH1 FTL GAK NECAP1 CHMP2B PLDN BLOC1S1 GJA1 GJA3 GJA4 GJA5 GJA8 GJB1 GJB2 GJB3 GJB5 SNX5 VPS4A CHMP2A GNS YIPF6 CHMP4A HSPA8 IGF2R ARCN1 ARF1 GJB7 BLOC1S3 M6PR ARRB1 MYO6 OCRL VPS36 SAR1B VPS28 SNX9 CHMP5 VTA1 CHMP3 PIK3C2A TBC1D8B VPS37C CNO ARFGAP1 GJC2 GJD2 RAB5C RPS27A SORT1 SEC13 SH3GL2 SNX2 SRC STX4 VAMP2 VAMP7 TFRC TJP1 TPD52 TPD52L1 TSG101 RPS27AP11 LOC643454 UBA52 CHMP6 VPS37B STAM GJA9 TXNDC5 CLTCL1 PICALM DTNBP1 VPS25 GJA10 AP3B1 VAMP8 GBF1 SNAP23 NAPA AP1S2 AP1M1 HIP1R HGS CHMP7 CHMP4C COPB2 VPS4B SEC24C PUM1 DNAJC6 SEC24D +REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS AP1M2 AP2M1 AP1S1 AP2S1 AP2A1 AP2A2 AP1B1 AP2B1 AP1G1 HLA-A ARF1 LCK ATP6V1H PACS1 B2M HLA-K AP1S2 AP1M1 CD4 CD8B CD28 +REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL CD96 LILRB2 CD226 LILRB1 HCST LILRB5 LILRB4 LILRA1 LILRB3 CD160 AMICA1 CD200R1 RAET1E CXADR FCGR2B FCGR3A KLRK1 HLA-A HLA-B HLA-C HLA-F HLA-G ICAM1 ICAM2 ICAM3 ICAM4 ITGAL ITGB1 ITGB2 ITGB7 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DL4 KIR2DS1 KIR2DS2 KIR3DL1 KIR3DL2 KLRC1 KLRD1 CRTAM B2M PVR PVRL2 SELL HLA-K LOC651536 LOC652578 LOC652626 LOC653879 C3 TYROBP LOC731066 VCAM1 ULBP3 ULBP2 ULBP1 IFITM1 CD3D CD3E CD3G CD247 CD8A CD8B CD19 CD34 CD40 CD40LG CD81 CDH1 +REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE CPT1A CPT1B CPT2 ACSL1 ACACB PRKAG2 CAB39 PRKAG3 STRADB PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 LOC644462 STK11 SLC25A20 CAB39L STRADA +REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM FASN PANK1 PANK4 PPCDC AASDHPPT PANK3 PPCS PANK2 SLC25A16 COASY SLC5A6 +REACTOME_BOTULINUM_NEUROTOXICITY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BOTULINUM_NEUROTOXICITY STX6 STX1B SYT2 STX2 STX12 LOC642105 SNAP25 STX1A STX3 STX4 STX5 VAMP1 VAMP2 SYT1 STX7 STX16 STX11 STX10 STX8 +REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS NAMPT GPHN SLC19A2 SLC46A1 GSTO2 CYB5A DHFR CYB5R3 FASN NMNAT2 QPRT FPGS TPK1 MOCS3 NMNAT3 MOCS1 MOCS2 MTHFD1 MTHFR ENPP1 PANK1 ACP5 MOCOS PNPO NADSYN1 PANK4 RFK PPCDC AASDHPPT DHFRP1 SHMT1 NMNAT1 SLC2A1 SLC2A3 NADK SLC19A1 THTPA PANK3 PPCS PANK2 FLAD1 SLC25A16 COASY SLC19A3 SLC25A32 PDXK SLC5A6 NFS1 GSTO1 SLC23A2 SLC23A1 +REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING AP1M2 TGOLN2 AP4B1 AP1S1 AP3S1 CLTA CLTC CPD CTSZ SH3D19 AP1B1 AP1G1 DNASE2 DNM2 AP4E1 SNAPIN FTH1 FTL GAK NECAP1 PLDN BLOC1S1 SNX5 GNS YIPF6 HSPA8 IGF2R ARF1 BLOC1S3 M6PR ARRB1 OCRL SNX9 PIK3C2A TBC1D8B CNO RAB5C SORT1 SH3GL2 SNX2 STX4 VAMP2 VAMP7 TFRC TPD52 TPD52L1 LOC643454 TXNDC5 PICALM DTNBP1 AP3B1 VAMP8 GBF1 SNAP23 NAPA AP1S2 AP1M1 HIP1R PUM1 DNAJC6 +REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS STX6 STX1B STX2 STX12 LOC642105 SNAP25 STX1A STX3 STX4 STX5 VAMP1 VAMP2 STX7 STX16 STX11 STX10 STX8 +REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY CCNO POLD3 FEN1 SMUG1 APEX1 LIG1 MPG MUTYH NTHL1 OGG1 PCNA POLB POLD1 POLD2 POLD4 TDG MBD4 +REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS F2 F7 F9 F10 GGCX FURIN PROC PROS1 LOC652612 VKORC1 PROZ +REACTOME_IL_7_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IL_7_SIGNALING HGF IL2RG IL7 IL7R JAK1 JAK3 PIK3R1 PIK3R2 STAT5A STAT5B PIK3R3 +REACTOME_CELL_CYCLE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_CYCLE KIF20A ACTR1A AKAP9 CDK2 CDK4 CDK6 PSMD14 CDK7 CDKN1A CDKN1B STAG1 CDKN2A CDKN2B CDKN2C CDKN2D TUBB4A TUBB4B SYCP2 ANAPC10 NDC80 TUBGCP3 DCTN2 CENPA CENPC1 CETN2 POLD3 NUDC PLK4 STAG3 STAG2 SDCCAG8 TUBGCP2 RUVBL2 DBF4 KIF2C CNTRL UBE2C DIDO1 CHEK1 FGFR1OP ZWINT CEP250 CHEK2 PMF1 DCTN3 OIP5 TUBGCP5 CKS1B NEDD1 HIST4H4 HIST3H2BB LIN54 PSMA8 CSNK1D CSNK1E SPC24 SGOL2 SGOL1 DCTN1 DHFR DKC1 DNA2 DYNC1H1 DYNC1I2 DYRK1A E2F1 E2F2 E2F3 E2F4 E2F5 TUBB SKA1 FEN1 CEP164 MAPRE1 NINL AZI1 PSME4 SYNE2 CLASP1 SYNE1 ITGB3BP ORC6 ORC3 POLA2 CDC26 CENPI HIST1H2BA SUN2 AHCTF1 POT1 NSL1 FBXO5 TINF2 SMC1B TUBG2 PPP2R3B LIN9 ANAPC2 RPA4 ANAPC4 HIST1H2AE HIST1H2AD H2AFX H2AFZ HIST1H2BD HIST1H2BB HDAC1 HSPA2 BIRC5 HSP90AA1 HUS1 SKA2 NUP43 INCENP APITD1 KIF2A LIG1 LMNA LMNB1 CENPP MAD2L1 MAX MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MDM2 MNAT1 LOC440577 LOC440917 LOC441488 MYBL2 MYC ATM NEK2 NPM1 NUMA1 ORC1 ORC2 ORC4 ORC5 PAFAH1B1 SYCP3 GMNN PCM1 PCNA PCNT ANAPC5 ANAPC7 ANAPC11 GINS2 RSF1 PLK1 MIS18A POLA1 POLD1 POLD2 POLE POLE2 TERF2IP ATR ERCC6L CCDC99 PPP1CC ZWILCH CEP192 WRAP53 HAUS2 CDCA8 PPP2CA PPP2CB CENPQ PPP2R1A PPP2R1B PPP2R2A PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E MIS18BP1 HJURP MCM10 HIST2H4B PRIM1 PRIM2 NHP2 PRKACA CEP72 NUP133 CDK5RAP2 PRKAR2B CENPJ CENPN RCC2 LIN37 TEX12 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 CASC5 PSMD3 PSMD4 PSMD5 NUP107 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 SPC25 TAOK1 POLD4 RAD1 RAD9A RAD17 RAD21 RANBP2 RANGAP1 RB1 RBBP4 RBBP7 RBL1 RBL2 CCND1 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 RPS27 RPS27A RRM2 CLIP1 SEC13 CENPK RBBP4P1 RFWD2 DHFRP1 LOC645084 ANAPC1 GORASP1 TUBBP2 LOC647654 LOC648152 CENPH LOC649620 SKP1 SKP2 ACD LOC650621 LOC651610 LOC651763 LOC651921 LOC652826 BRCA1 AURKA SYCP1 BUB1 BUB1B TERF1 TERF2 TERT TFDP1 TK2 TP53 HIST2H2AA4 TUBA4A TUBG1 RPS27AP11 SKA2L RFWD2P1 TYMS CDC26P1 LOC729964 LOC730418 LOC730594 UBA52 UBE2D1 UBE2E1 UBE2I WEE1 XPO1 YWHAE YWHAG ALMS1 TUBA1A MIS12 CENPM NUP37 CENPO MLF1IP NUP85 CEP76 DSN1 CENPT CEP290 CEP63 CEP70 B9D2 NDEL1 CDT1 SEH1L KIF18A SMC1A HIST3H3 HIST1H4I CDC7 CDC45 HIST1H2AJ HIST1H2AC HIST1H2AB HIST2H2AA3 HIST2H2AC HIST1H2BG HIST1H2BL HIST1H2BN HIST1H2BM HIST1H2BF HIST1H2BE HIST1H2BH HIST1H2BI HIST1H2BC HIST1H2BO HIST2H2BE NUF2 HIST1H4A HIST1H4D HIST1H4F HIST1H4K HIST1H4J HIST1H4C HIST1H4H HIST1H4B HIST1H4E HIST1H4L HIST2H4A MAD1L1 ATRIP GINS4 MCM8 CUL1 KIF2B SMARCA5 FKBP6 OFD1 HIST1H2BK TUBGCP6 CDC14A RUVBL1 SSNA1 DYNLL1 CDC23 CDC16 CCNA2 CCNA1 CCNB1 CCND2 BTRC CCND3 HIST1H2BJ CCNE1 CCNH PKMYT1 SMC3 CCNB2 CCNE2 CENPL LIN52 ZW10 BUB3 AURKB PTTG1 PSMF1 KIF23 CEP41 CEP135 CEP57 KNTC1 CKAP5 CDK1 GINS1 PSMD6 CDC6 CDC20 CDC25A CDC25B CDC25C CDC27 REC8 +REACTOME_SIGNALING_BY_ERBB4 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_ERBB4 AKT3 CDKN1A CDKN1B YAP1 WWP1 CHUK THEM4 CREB1 CSH1 CSN2 NRG4 HBEGF EGF EGFR ERBB3 ERBB4 EREG AKT1 AKT2 ESR1 FOXO1 FOXO3 TAB2 PHLPP1 NCSTN MTOR RICTOR SH2B1 GFAP GH1 GH2 GHR GRB2 GSK3A NRG1 NR4A1 HRAS JAK2 KRAS MDM2 FOXO4 NEDD4 NRAS APH1A PDPK1 WWOX PGR PIK3CA PIK3R1 PSENEN MAPK1 MAPK3 MAP2K1 MAP2K2 PRL PRLR PSEN1 PSEN2 BAD PTEN TRIB3 RAF1 RPS6KB2 RPS27A S100B CXCL12 MLST8 SHC1 SKP1 SOS1 STAT5A STAT5B BTC ADAM17 TSC2 RPS27AP11 LOC729120 UBA52 LOC731292 YWHAB MAPKAP1 APH1B CASP9 AKT1S1 CUL1 BTRC NRG2 NCOR1 CDK1 RBX1 +REACTOME_ORC1_REMOVAL_FROM_CHROMATIN http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ORC1_REMOVAL_FROM_CHROMATIN CDK2 PSMD14 CDKN1A CDKN1B PSMA8 PSME4 ORC6 ORC3 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 ORC1 ORC2 ORC4 ORC5 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RB1 RPS27A LOC652826 RPS27AP11 UBA52 CDT1 MCM8 CCNA2 CCNA1 PSMF1 PSMD6 CDC6 +REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS MUC12 B3GNT3 ST6GALNAC2 B3GNT2 GALNT6 GALNT5 GALNT13 GALNTL2 MUCL1 MUC17 MUC15 B3GNTL1 GALNTL5 B3GNT6 ST6GALNAC3 GALNT1 GALNT2 GALNT3 GALNT8 GCNT1 ST6GALNAC4 C1GALT1C1 GALNTL4 B3GNT8 MUC21 GALNTL6 MUC2 MUC4 MUC5AC MUC6 MUC7 GALNT9 GCNT4 GALNT7 GALNT10 MUC13 C1GALT1 GALNTL1 MUC3B GALNT11 WBSCR17 GCNT6 ST6GAL1 ST3GAL1 ST3GAL2 ST3GAL3 LOC652741 MUC5B MUC19 LOC732162 B3GNT4 GALNT14 GALNT12 B3GNT5 B3GNT9 GCNT3 B3GNT7 B4GALT5 MUC16 +REACTOME_SULFUR_AMINO_ACID_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SULFUR_AMINO_ACID_METABOLISM CDO1 SLC25A10 CTH AHCY ETHE1 GCLC GCLM MAT2B GOT1 MAT1A MAT2A MTAP MTR APIP CSAD ADI1 CNDP2 SQRDL ENOPH1 BHMT SUOX TST MRI1 CBS +REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING AKT3 RNF41 ERBB2 ERBB3 AKT1 AKT2 NRG1 RPS27A RPS27AP11 UBA52 USP8 NRG2 +REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES NUP50 NUPL2 USP18 NUP35 EIF4A1 EIF4A2 EIF4E EIF4G1 EIF4G2 NUP205 FLNB NUP210 NUP188 DDX58 NUP62 ARIH1 EIF4E3 IFIT1 NUP43 IRF3 JAK1 KPNA1 KPNB1 KPNA2 KPNA3 KPNA4 KPNA5 MX1 MX2 NEDD4 NUP88 HERC5 PIN1 PLCG1 NUP54 PPM1B NUP133 MAPK3 EIF2AK2 NUP107 RANBP2 RPS27A STAT1 TPR RPS27AP11 UBA52 UBA7 UBE2E1 UBE2N TRIM25 NUP37 NUP85 NUP214 AAAS SEH1L RAE1 EIF4G3 UBE2L6 EIF4E2 NUP155 ISG15 NUP93 EIF4A3 NUPL1 POM121 NUP153 +REACTOME_PROLACTIN_RECEPTOR_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROLACTIN_RECEPTOR_SIGNALING CSH1 SH2B1 GH1 GH2 GHR JAK2 PRL PRLR SKP1 STAT5A STAT5B CUL1 BTRC RBX1 +REACTOME_SIGNALING_BY_ERBB2 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_ERBB2 AKT3 RNF41 CDKN1A CDKN1B STUB1 ADCY1 ADCY2 ADCY3 ADCY5 CDC37 ADCY6 ADCY7 ADCY8 CHUK ADCY9 THEM4 CREB1 NRG4 ADRBK1 HBEGF EGF EGFR ADCY4 ERBB2 ERBB3 ERBB4 EREG AKT1 AKT2 FOXO1 FOXO3 PHLPP1 MTOR RICTOR FYN GAB1 GRB2 GRB7 GSK3A NRG1 NR4A1 HRAS HSP90AA1 ITPR2 ITPR3 KRAS MATK MDM2 FOXO4 NRAS PDE1A PDE1B PDPK1 PIK3CA PIK3R1 PLCG1 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCD PRKCE PRKCG MAPK1 MAPK3 MAP2K1 MAP2K2 BAD PTEN TRIB3 RAF1 RPS6KB2 RPS27A MLST8 SHC1 SOS1 SRC BTC TSC2 RPS27AP11 LOC729120 LOC730418 UBA52 LOC731292 YES1 YWHAB MAPKAP1 CALM1 CALM2 CUL5 CALM3 CAMK4 CASP9 AKT1S1 USP8 NRG2 CDK1 +REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS COL4A3BP SPTLC1 DEGS2 ACER1 SGPP2 CSNK1G2 PPM1L SGMS2 CERS3 KDSR CERS6 SGMS1 CERS2 ACER2 OSBP ACER3 PRKD1 SPHK2 LOC729155 CERS4 SGPP1 DEGS1 PPAP2A PPAP2C PPAP2B SPHK1 SGPL1 CERS5 VAPB VAPA SPTLC2 +REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS MUC12 ST6GALNAC2 MUCL1 MUC17 MUC15 ST6GALNAC3 ST6GALNAC4 MUC21 MUC2 MUC4 MUC5AC MUC6 MUC7 MUC13 MUC3B ST6GAL1 ST3GAL1 ST3GAL2 ST3GAL3 LOC652741 MUC5B MUC19 LOC732162 MUC16 +REACTOME_DEFENSINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DEFENSINS DEFB118 CCR2 CCR6 DEFB104A DEFB127 DEFB129 DEFA1 DEFA3 DEFA4 DEFA5 DEFA6 DEFB1 DEFB4A DEFB105A DEFB106A DEFB107A DEFB108B DEFB110 DEFB112 DEFB113 DEFB114 DEFB115 DEFB116 DEFB119 DEFB121 DEFB123 DEFB124 DEFB125 DEFB128 DEFB130 DEFB132 DEFB103A ART1 DEFB107B DEFB104B DEFB106B DEFB105B DEFB103B PRSS2 DEFB135 DEFB136 DEFB134 DEFB131 TLR1 TLR2 DEFA1B DEFB4B LOC729523 LOC731949 DEFB126 CD4 +REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR CDC37 EGF EGFR GAB1 GRB2 HRAS HSP90AA1 KRAS NRAS PIK3CA PIK3R1 PLCG1 RPS27A SHC1 SOS1 RPS27AP11 UBA52 CBL +REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING NRG4 HBEGF EGF EGFR ERBB2 ERBB4 EREG GRB2 NRG1 HRAS KRAS NRAS MAPK1 MAPK3 MAP2K1 MAP2K2 RAF1 SOS1 BTC YWHAB NRG2 CDK1 +REACTOME_SIGNALING_BY_EGFR_IN_CANCER http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_EGFR_IN_CANCER AKT3 ADAM10 SPRY1 SPRY2 STAM2 CDKN1A CDKN1B ADCY1 ADCY2 ADCY3 ADCY5 CDC37 ADCY6 ADCY7 ADCY8 CHUK ADCY9 THEM4 AP2M1 AP2S1 CLTA CLTC CREB1 CSK ADRBK1 AP2A1 AP2A2 AP2B1 EGF EGFR ADCY4 EPS15 AKT1 AKT2 FOXO1 FOXO3 PHLPP1 MTOR RICTOR GAB1 LRIG1 GRB2 GSK3A EPN1 SH3KBP1 NR4A1 HRAS HSP90AA1 ITPR2 ITPR3 KRAS MDM2 FOXO4 NRAS PDE1A PDE1B PDPK1 PIK3CA PIK3R1 PLCG1 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCD PRKCE PRKCG PAG1 MAPK1 MAPK3 MAP2K1 MAP2K2 BAD PTEN TRIB3 EPS15L1 RAF1 RPS6KB2 RPS27A MLST8 SH3GL2 SHC1 SOS1 SRC ADAM17 TSC2 RPS27AP11 LOC729120 LOC730418 UBA52 LOC731292 YWHAB MAPKAP1 CALM1 STAM ADAM12 CALM2 CALM3 CAMK4 CASP9 AKT1S1 CBL HGS CDK1 CDC42 +REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS VPS37A VPS37D VPS28 VPS37C RPS27A TSG101 RPS27AP11 UBA52 VPS37B NMT2 +REACTOME_BETA_DEFENSINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BETA_DEFENSINS DEFB118 CCR2 CCR6 DEFB104A DEFB127 DEFB129 DEFB1 DEFB4A DEFB105A DEFB106A DEFB107A DEFB108B DEFB110 DEFB112 DEFB113 DEFB114 DEFB115 DEFB116 DEFB119 DEFB121 DEFB123 DEFB124 DEFB125 DEFB128 DEFB130 DEFB132 DEFB103A DEFB107B DEFB104B DEFB106B DEFB105B DEFB103B DEFB135 DEFB136 DEFB134 DEFB131 TLR1 TLR2 DEFB4B LOC729523 LOC731949 DEFB126 +REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE SEC61B RPL35 RPL7AP27 DDOST FAU TRAM1 SEC11A SEC61G RPL13A RPL36 RPL10P16 FAM153A SPCS1 SEC61A1 RPL36P14 RPSAP12 RPS8P10 RPL7AP66 RPL10P9 RPS12P4 RPSA RPS26P10 RPL23AP2 RPS12P22 RPL21P29 RPS26P35 RPL10A RPL26L1 SEC61A2 SRPRB SPCS3 RPL3 RPL3L RPL4 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL10 RPL11 RPL12 RPL13 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL23A RPL24 RPL26 RPL27 RPL30 RPL27A RPL28 RPL29 RPL31 RPL32 RPL34 RPL35A RPL37 RPL37A RPL38 RPL39 RPL41 RPL36A RPLP0 RPLP1 RPLP2 RPN1 RPN2 RPS2 RPS3 RPS3A RPS4X RPS4Y1 RPS5 RPS6 RPS7 RPS8 RPS9 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS18 RPS19 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS28 RPS29 RPL6P19 LOC641895 RPL36AP31 RPS29P3 RPS26P28 RPL36AP8 RPL26P22 RPS26P20 RPS15AP11 RPS26P50 RPL22P11 RPL17P6 RPS13P8 RPS28P4 RPL32P16 LOC646184 RPS28P7 RPL12P2 LOC647074 RPL23AP42 RPL5P1 RPL36AP51 LOC649602 LOC650638 RPS28P9 RPL34P27 LOC651825 LOC651894 RPL26P30 RPSAP9 SRP9P1 RPL19P9 LOC653566 RPL21P119 RPL31P17 LOC653881 SRP9 SRP14 SRP19 SRP54 SRP68 SRP72 SRPR SSR1 SSR2 SSR3 SSR4 RPL31P31 RPL15P17 RPL23AP18 RPL26P24 RPL21P75 RPS27AP11 RPS26P7 RPL21P134 RPS26P25 RPS19P3 RPL36AP23 RPS18P10 RPL17P36 RPL36AP37 RPL21P16 RPL23AP74 RPS15P5 RPL23AP63 RPS10P9 LOC730343 RPS18P5 UBA52 RPL34P31 RPL14 SEC11C RPL23 SPCS2 +REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING AKT3 CDKN1A CDKN1B CHUK THEM4 CREB1 NRG4 HBEGF ERBB4 EREG AKT1 AKT2 FOXO1 FOXO3 PHLPP1 MTOR RICTOR GSK3A NRG1 NR4A1 MDM2 FOXO4 PDPK1 PIK3CA PIK3R1 BAD PTEN TRIB3 RPS6KB2 MLST8 BTC TSC2 LOC729120 LOC731292 MAPKAP1 CASP9 AKT1S1 NRG2 +REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING NRG4 HBEGF ERBB4 EREG GRB2 NRG1 HRAS KRAS NRAS MAPK1 MAPK3 MAP2K1 MAP2K2 RAF1 SHC1 SOS1 BTC YWHAB NRG2 CDK1 +REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING AKT3 CDKN1A CDKN1B CHUK THEM4 CREB1 NRG4 HBEGF EGF EGFR ERBB2 ERBB3 ERBB4 EREG AKT1 AKT2 FOXO1 FOXO3 PHLPP1 MTOR RICTOR GAB1 GRB2 GSK3A NRG1 NR4A1 MDM2 FOXO4 PDPK1 PIK3CA PIK3R1 BAD PTEN TRIB3 RPS6KB2 MLST8 BTC TSC2 LOC729120 LOC731292 MAPKAP1 CASP9 AKT1S1 NRG2 +REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 YAP1 CSH1 CSN2 NRG4 HBEGF ERBB4 EREG ESR1 TAB2 NCSTN SH2B1 GFAP GH1 GH2 GHR NRG1 JAK2 APH1A WWOX PGR PSENEN PRL PRLR PSEN1 PSEN2 S100B CXCL12 SKP1 STAT5A STAT5B BTC ADAM17 APH1B CUL1 BTRC NRG2 NCOR1 RBX1 +REACTOME_GLYCOSPHINGOLIPID_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLYCOSPHINGOLIPID_METABOLISM NEU3 NEU4 ARSK ARSG GALC SUMF2 GBA GLA GLB1 GM2A SUMF1 HEXA HEXB ENPP7 ARSI ARSH ARSA ARSB STS ARSE ARSF ASAH1 NEU1 NEU2 CTSA SMPD3 SMPD4 PSAP ASAH2 GBA2 GBA3 CERK ASAH2C SMPD1 SMPD2 UGCG ARSJ GAL3ST1 +REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION MED6 MED16 CDK8 YAP1 NCOA2 PPARGC1A GLIPR1 MED8 APOA5 PLIN2 PPARGC1B CPT1A CPT2 CREBBP CTGF CYP1A1 CYP4A11 CYP7A1 AGT ABCA1 EP300 ESRRA ALAS1 FABP1 ACSL1 MED19 FDFT1 FHL2 NCOA6 CDK19 MED13L WWTR1 TIAM2 ANKRD1 TNFRSF21 MED4 GRHL1 HMGCR HMGCS1 HMGCS2 APOA1 APOA2 ACADM SLC27A1 FADS1 MED11 ARNTL ME1 NFYA NFYB NPAS2 NRF1 G0S2 ACOX1 MED31 ANGPTL4 MED15 ABCB4 UGT1A9 PPARA PPARG MED1 MED18 MED9 MED29 TRIB3 RORA RXRA SMARCD3 SREBF1 SREBF2 SULT2A1 MED22 TBL1X TEAD1 TEAD4 TEAD3 TXNRD1 TBL1XR1 MED25 NCOA3 MED10 TEAD2 PRIC285 NCOA1 PEX11A HDAC3 CCNC MED30 MED14 MED21 MED23 MED17 MED26 MED27 MED7 MED20 CD36 NR1D1 CLOCK NCOR1 TGS1 MED24 MED12 +REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX E2F1 E2F2 E2F3 ORC3 ORC1 ORC2 ORC4 ORC5 GMNN RPS27A RPS27AP11 UBA52 CDT1 CDC6 +REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI RIPK3 CHUK TICAM1 AGER HMGB1 APP IKBKB NFKB2 NFKBIA NFKBIB RELA S100A12 S100B SAA1 TLR3 ZBP1 IKBKG RIPK1 +REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION MAMLD1 CREBBP E2F1 E2F3 EIF2C3 EIF2C4 EP300 SNW1 TNRC6B KAT2A EIF2C1 EIF2C2 TNRC6A RBPJ JUN MOV10 LOC441488 NOTCH2 NOTCH3 NOTCH4 MAML3 TNRC6C CCND1 TFDP1 TP53 LOC728030 MAML2 KAT2B MAML1 +REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX MMP24 CMA1 CTRB1 CTSG ELANE KLK2 KLKB1 MMP1 MMP2 MMP3 MMP7 MMP8 MMP9 MMP10 MMP11 MMP13 MMP14 MMP15 MMP16 MMP17 CTRB2 FURIN PLG PRSS1 PRSS2 MMP25 TIMP1 TIMP2 TPSAB1 +REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT COX17 SLC25A13 TIMM17B TIMM23B TIMM17A TOMM40 TIMM44 MTX2 DNAJC19 CHCHD4 GRPEL2 CS HSCB CYC1 TIMM8A LDHD PMPCA FXN SAMM50 FXC1 TIMM13 TIMM10 TIMM9 TIMM8B GFER COQ2 C18orf55 SLC25A4 SLC25A6 TIMM22 HSPA9 HSPD1 IDH3G TOMM5 LOC440490 MTX1 ATP5A1 ACO2 ATP5B PAM16 ATP5G1 TOMM7 TOMM22 BCS1L LOC642727 LOC644589 LOC646675 LOC646677 LOC650667 LOC650674 TAZ VDAC1 GRPEL1 SLC25A12 TIMM50 PMPCB TOMM20 TOMM70A +REACTOME_SIGNALING_BY_HIPPO http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_HIPPO YAP1 AMOT AMOTL1 DVL2 WWC1 WWTR1 NPHP4 LATS2 LOC440917 AMOTL2 MOB1A SAV1 LOC646561 STK3 STK4 TJP1 YWHAB YWHAE CASP3 LATS1 MOB1B TJP2 +REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS ADAM10 DTX2 CNTN1 MIB2 JAG1 DTX1 DTX4 NCSTN DLL1 JAG2 ARRB1 ARRB2 APH1A DLL4 PSENEN PSEN1 PSEN2 MIB1 RPS27A ADAM17 RPS27AP11 UBA52 APH1B NUMB DLK1 NEURL DNER +REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR CNPY3 CTSB CTSK CTSL1 CTSS UNC93B6 UNC93B2 TLR7 TLR8 TLR9 LGMN TLR3 HSP90B1 UNC93B1 +REACTOME_SIGNALING_BY_NOTCH4 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_NOTCH4 ADAM10 JAG1 NCSTN DLL1 JAG2 NOTCH4 APH1A DLL4 PSENEN PSEN1 PSEN2 APH1B +REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR AKT3 RASGRP1 PSMD14 CDKN1A CDKN1B MALT1 CHUK THEM4 CREB1 PSMA8 AKT1 AKT2 FOXO1 FOXO3 PSME4 PHLPP1 FBXW11 MTOR RICTOR RASGRP3 GSK3A NR4A1 HRAS IKBKB KRAS MDM2 FOXO4 NFKBIA NFKBIB NFKBIE NRAS PDPK1 PRKCB PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 BAD PSME1 PSME2 PTEN TRIB3 REL RELA RPS6KB2 RPS27A MLST8 LOC646626 SKP1 LOC652826 MAP3K7 TSC2 RPS27AP11 LOC729120 UBA52 LOC731292 MAPKAP1 CASP9 AKT1S1 CARD11 CUL1 IKBKG BCL10 BTRC PSMF1 PSMD6 +REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS PSMD14 MALT1 CHUK PSMA8 PSME4 FBXW11 IKBKB NFKBIA NFKBIB NFKBIE PRKCB PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 REL RELA RPS27A LOC646626 SKP1 LOC652826 MAP3K7 RPS27AP11 UBA52 CARD11 CUL1 IKBKG BCL10 BTRC PSMF1 PSMD6 +REACTOME_RORA_ACTIVATES_CIRCADIAN_EXPRESSION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RORA_ACTIVATES_CIRCADIAN_EXPRESSION NCOA2 PPARGC1A CPT1A CREBBP EP300 NCOA6 ARNTL NPAS2 PPARA MED1 RORA RXRA SMARCD3 SREBF1 TBL1X TBL1XR1 NCOA3 PRIC285 NCOA1 HDAC3 NR1D1 CLOCK NCOR1 TGS1 +REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS PIK3AP1 FYN GRB2 BLNK SH3KBP1 ITPR2 ITPR3 LYN NCK1 PIK3CD PIK3R1 PLCG1 PLCG2 BLK SHC1 SOS1 STIM1 SYK BTK VAV1 CALM1 CALM2 CALM3 ORAI1 CBL CBLB CD19 CD79A CD79B +REACTOME_REGULATION_OF_COMPLEMENT_CASCADE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_COMPLEMENT_CASCADE CFHR3 CR1 CD55 CFH CFI CD46 PROS1 CFB LOC653879 C2 C3 C4A C4BPA C4BPB +REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION YAP1 NCOA2 CREBBP CTGF NCOA6 WWTR1 NPPA PPARA MED1 RXRA SMARCD3 TBL1X TBX5 TEAD1 TEAD4 TEAD3 TBL1XR1 NCOA3 TEAD2 PRIC285 RUNX2 NCOA1 KAT2B TGS1 +REACTOME_SIGNALING_BY_NOTCH2 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_NOTCH2 ADAM10 JAG1 NCSTN DLL1 JAG2 NOTCH2 APH1A DLL4 PSENEN PSEN1 PSEN2 APH1B +REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING MAMLD1 ST3GAL6 TMED2 CREBBP E2F1 E2F3 EIF2C3 EIF2C4 EP300 SNW1 TNRC6B POFUT1 KAT2A EIF2C1 B4GALT1 EIF2C2 TNRC6A RBPJ JUN LFNG MFNG MOV10 LOC441488 NOTCH2 NOTCH3 NOTCH4 ATP2A1 ATP2A2 ATP2A3 FURIN MAML3 POGLUT1 TNRC6C RAB6A CCND1 RFNG SEL1L ST3GAL3 TFDP1 TP53 LOC728030 MAML2 KAT2B MAML1 +REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR AKT3 RASGRP1 PSMD14 CDKN1A CDKN1B MALT1 CHUK THEM4 PIK3AP1 CREB1 PSMA8 AKT1 AKT2 FOXO1 FOXO3 PSME4 PHLPP1 FBXW11 MTOR RICTOR FYN RASGRP3 GRB2 GSK3A BLNK SH3KBP1 NR4A1 HRAS IKBKB ITPR2 ITPR3 KRAS LYN MDM2 FOXO4 NCK1 NFKBIA NFKBIB NFKBIE NRAS PDPK1 PIK3CD PIK3R1 PLCG1 PLCG2 PRKCB PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 BAD PSME1 PSME2 PTEN TRIB3 REL RELA RPS6KB2 RPS27A BLK MLST8 SHC1 LOC646626 SKP1 LOC652826 SOS1 STIM1 SYK MAP3K7 BTK TSC2 RPS27AP11 LOC729120 UBA52 LOC731292 VAV1 MAPKAP1 CALM1 CALM2 CALM3 CASP9 AKT1S1 CARD11 CUL1 ORAI1 IKBKG CBL CBLB BCL10 BTRC CD19 PSMF1 CD79A CD79B PSMD6 +REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION CRTAP LEPREL2 MMP24 CMA1 COL1A1 COL1A2 COL2A1 COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL5A1 COL5A2 COL6A1 COL6A2 COL6A3 COL7A1 COL8A1 COL8A2 COL9A1 COL9A2 COL9A3 COL10A1 COL11A1 COL11A2 COL12A1 COL13A1 COL15A1 COL16A1 COL17A1 COL19A1 ADAMTS14 CTRB1 CTSG COL22A1 ELANE GLT25D2 COL24A1 PCOLCE2 COL28A1 KLK2 KLKB1 MMP1 MMP2 MMP3 MMP7 MMP8 MMP9 MMP10 MMP11 MMP13 MMP14 MMP15 MMP16 MMP17 CTRB2 P4HB FURIN COL5A3 PCOLCE PLG PLOD1 PLOD2 PPIB LEPREL1 PRSS1 PRSS2 MMP25 BMP1 TIMP1 TIMP2 TLL1 TLL2 TPSAB1 COL14A1 GLT25D1 COL21A1 COL25A1 COL27A1 SERPINH1 PLOD3 COL23A1 ADAMTS3 ADAMTS2 +REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION HDAC6 HDAC5 MAMLD1 CDK8 CREBBP EP300 SNW1 HEY1 HEY2 KAT2A HEYL HDAC1 HDAC2 HIF1A HES1 RBPJ HES5 MYC HDAC7 FBXW7 MAML3 HDAC8 RPS27A SKP1 TBL1X TLE1 TLE2 TLE3 TLE4 LOC728030 RPS27AP11 UBA52 TBL1XR1 HDAC11 HDAC10 MAML2 CUL1 HDAC3 KAT2B CCNC NCOR1 NCOR2 HDAC9 HDAC4 MAML1 RBX1 +REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA NCOA2 PPARGC1A CREBBP EP300 NCOA6 ARNTL NPAS2 PPARA MED1 RORA RXRA SMARCD3 TBL1X TBL1XR1 NCOA3 ELOVL3 PRIC285 NCOA1 HDAC3 NR1D1 CLOCK NCOR1 TGS1 +REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI ST3GAL6 TMED2 B4GALT1 LFNG MFNG NOTCH2 NOTCH3 NOTCH4 ATP2A1 ATP2A2 ATP2A3 FURIN RAB6A RFNG SEL1L ST3GAL3 +REACTOME_SIGNALING_BY_NOTCH1 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_NOTCH1 HDAC6 HDAC5 MAMLD1 ADAM10 CDK8 DTX2 CNTN1 CREBBP MIB2 JAG1 DTX1 EP300 SNW1 DTX4 NCSTN HEY1 HEY2 KAT2A HEYL DLL1 HDAC1 HDAC2 HIF1A HES1 RBPJ JAG2 HES5 ARRB1 ARRB2 MYC APH1A HDAC7 DLL4 FBXW7 MAML3 PSENEN HDAC8 PSEN1 PSEN2 MIB1 RPS27A SKP1 ADAM17 TBL1X TLE1 TLE2 TLE3 TLE4 LOC728030 RPS27AP11 UBA52 TBL1XR1 HDAC11 APH1B HDAC10 MAML2 CUL1 NUMB DLK1 HDAC3 KAT2B CCNC NEURL DNER NCOR1 NCOR2 HDAC9 HDAC4 MAML1 RBX1 +REACTOME_SIGNALING_BY_NOTCH3 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_NOTCH3 ADAM10 JAG1 NCSTN DLL1 JAG2 NOTCH3 APH1A DLL4 PSENEN PSEN1 PSEN2 APH1B +REACTOME_TRIGLYCERIDE_BIOSYNTHESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRIGLYCERIDE_BIOSYNTHESIS AGPAT1 AGPAT2 AGPAT6 GPAT2 ACSL1 ACSL3 ACSL4 FASN GPD1L LPIN1 ACSL6 LCLAT1 LPCAT4 GK GPD1 ACACA ACLY HSD17B12 ACSL5 ELOVL2 AGPAT5 AGPAT3 AGPAT4 GPAM ELOVL5 ELOVL1 LPIN3 SLC25A1 ELOVL4 ELOVL6 LPCAT1 ELOVL7 ELOVL3 DGAT2 AGPAT9 DGAT1 TECR LPIN2 +REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE FRS2 THEM4 CRK KLB DOK1 EIF4B EIF4E EIF4EBP1 EIF4G1 AKT2 FGF1 FGF2 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGF10 FGFR1 FGFR3 FGFR2 FGFR4 MTOR GAB1 SHC2 FGF20 FGF22 GRB2 GRB10 EEF2K PIK3R4 HRAS INS INSR IRS1 KRAS NRAS PDE3B PRKAG2 PDPK1 CAB39 PIK3C3 PIK3CA PIK3CB PIK3R1 PIK3R2 SHC3 PRKAG3 TLR9 PPM1A STRADB PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 MAPK1 MAPK3 MAP2K1 MAP2K2 RPTOR TRIB3 RAF1 RHEB RPS6 RPS6KB1 MLST8 LOC644462 SHC1 SOS1 STK11 TSC1 TSC2 LOC729120 LOC730244 YWHAB FGF23 CAB39L IRS2 FGF18 FGF17 STRADA KL CDK1 FGF19 +REACTOME_ARMS_MEDIATED_ACTIVATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ARMS_MEDIATED_ACTIVATION CRK RAPGEF1 HRAS KRAS NGF NRAS NTRK1 MAPK1 MAPK3 MAP2K1 MAP2K2 KIDINS220 RAF1 RAP1A BRAF YWHAB CDK1 +REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS FRS2 CRK RAPGEF1 HRAS KRAS NGF NRAS NTRK1 PLCG1 MAPK1 MAPK3 MAP2K1 MAP2K2 KIDINS220 RAF1 RAP1A BRAF YWHAB CDK1 +REACTOME_SIGNALLING_TO_RAS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALLING_TO_RAS MAPK14 SHC2 GRB2 HRAS KRAS NGF NRAS NTRK1 SHC3 MAPK1 MAPK3 MAPK11 MAPK13 MAP2K1 MAP2K2 RAF1 RALA RALB RALGDS MAPK12 SHC1 SOS1 SRC YWHAB MAPKAPK3 MAPKAPK2 CDK1 +REACTOME_SIGNALING_BY_BMP http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_BMP FSTL1 SMAD1 SMAD4 SMAD5 SMAD6 SMAD7 SMURF1 GREM2 SMURF2 SKI BMP2 BMPR1A BMPR1B BMPR2 LOC731429 UBE2D1 UBE2D3 CHRDL1 ACVR2A NOG ACVR2B CER1 ZFYVE16 +REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL MERTK SLC7A9 AMICA1 COL1A1 COL1A2 LOC128192 LOC131691 SIRPA CXADR F2 FCER1G FN1 SLC7A8 SLC16A8 SLC7A11 PPIL2 FYN ANGPT1 ANGPT2 GRB2 GRB7 GRB14 HRAS APOB PPIAP8 ITGA3 ITGA5 ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 KRAS L1CAM LCK LYN MAG MMP1 ATP1B1 ATP1B2 ATP1B3 NRAS OLR1 F11R ANGPT4 PECAM1 PF4 PF4V1 PIK3CA PIK3CB PIK3R1 PIK3R2 PLCG1 TREM1 PPIA SIRPG PROC PROS1 SLC7A10 PTPN6 JAM2 SELL SELP LOC643997 SHC1 SLC3A2 LOC652612 PPIAP22 LOC654188 SLC16A1 SOS1 SPN SRC BSG TEK THBD YES1 SLC7A5 JAM3 CAV1 DOK2 SLC7A7 SLC7A6 ESAM SLC16A3 CD2 CD47 CD48 CD58 +REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE AKT3 DNAL4 CDKN1A CDKN1B ADCY1 ADCY2 FRS2 ADCY3 ADCY5 ADCY6 ADCY7 ADCY8 CHUK ADCY9 ADCYAP1 ADCYAP1R1 THEM4 AP2M1 AP2S1 CLTA CLTC ADORA2A CREB1 CRK MAPK14 ADRBK1 AP2A1 AP2A2 AP2B1 DNM1 DNM2 DUSP3 DUSP4 DUSP6 DUSP7 ADCY4 ELK1 AKT1 AKT2 FOXO1 FOXO3 PHLPP1 MTOR RICTOR SHC2 GRB2 RAPGEF1 GSK3A NR4A1 HRAS IRS1 ITPR2 ITPR3 KRAS RHOA MDM2 MEF2A MEF2C FOXO4 ATF1 NGF NRAS NTRK1 NTRK2 PDE1A PDE1B PDPK1 PIK3CA PIK3CB PIK3R1 PIK3R2 PLCG1 SHC3 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCD PRKCE PRKCG MAPK1 MAPK3 MAPK7 MAPK11 MAPK13 MAP2K1 MAP2K2 MAP2K5 BAD PTEN KIDINS220 TRIB3 RAF1 RALA RALB RALGDS RAP1A RIT2 RIT1 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KB2 MAPK12 MLST8 SH3GL2 SHC1 SOS1 SRC BRAF STAT3 TSC2 LOC729120 LOC730418 LOC731292 YWHAB MAPKAPK3 MAPKAP1 CALM1 CALM2 CALM3 CAMK4 CASP9 AKT1S1 IRS2 RPS6KA5 MAPKAPK2 CDK1 +REACTOME_SIGNALLING_TO_ERKS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALLING_TO_ERKS FRS2 CRK MAPK14 SHC2 GRB2 RAPGEF1 HRAS KRAS NGF NRAS NTRK1 PLCG1 SHC3 MAPK1 MAPK3 MAPK11 MAPK13 MAP2K1 MAP2K2 KIDINS220 RAF1 RALA RALB RALGDS RAP1A RIT2 RIT1 MAPK12 SHC1 SOS1 SRC BRAF YWHAB MAPKAPK3 MAPKAPK2 CDK1 +REACTOME_P38MAPK_EVENTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_P38MAPK_EVENTS MAPK14 HRAS KRAS NRAS MAPK11 MAPK13 RALA RALB RALGDS MAPK12 SRC MAPKAPK3 MAPKAPK2 +REACTOME_ACYL_CHAIN_REMODELLING_OF_PI http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACYL_CHAIN_REMODELLING_OF_PI PLA2G16 PLA2G4F PLA2G2D PLA2G4D PLA2G2E PLA2G1B PLA2G2A PLA2G4A PLA2G5 PLA2G2F MBOAT7 PLBD1 PLA2G12A PLA2G10 PLA2G4C +REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION FKBP1A ARHGEF18 RHOA F11R PARD6A PRKCZ PARD3 SMURF1 CGN RPS27A TGFB1 TGFBR1 TGFBR2 RPS27AP11 UBA52 LOC731429 +REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING STUB1 STRAP PPP1R15A SMAD2 SMAD3 SMAD7 UCHL5 PPP1CA PPP1CB PPP1CC PMEPA1 SMURF1 RPS27A SMURF2 TGFB1 TGFBR1 TGFBR2 RPS27AP11 UBA52 LOC731429 XPO1 MTMR4 ZFYVE9 +REACTOME_COLLAGEN_FORMATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_COLLAGEN_FORMATION CRTAP LEPREL2 COL1A1 COL1A2 COL2A1 COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL5A1 COL5A2 COL6A1 COL6A2 COL6A3 COL7A1 COL8A1 COL8A2 COL9A1 COL9A2 COL9A3 COL10A1 COL11A1 COL11A2 COL12A1 COL13A1 COL15A1 COL16A1 COL17A1 COL19A1 ADAMTS14 COL22A1 GLT25D2 COL24A1 PCOLCE2 COL28A1 P4HB COL5A3 PCOLCE PLOD1 PLOD2 PPIB LEPREL1 BMP1 TLL1 TLL2 COL14A1 GLT25D1 COL21A1 COL25A1 COL27A1 SERPINH1 PLOD3 COL23A1 ADAMTS3 ADAMTS2 +REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION CDK8 CDK9 CDKN2B E2F4 E2F5 WWTR1 HDAC1 JUNB SMAD2 SMAD3 SMAD4 SMAD7 MEN1 LOC441488 MYC SERPINE1 RBL1 TGIF2 RPS27A SP1 TFDP1 TGIF1 RPS27AP11 UBA52 CCNC CCNT1 CCNT2 +REACTOME_SIGNALING_BY_FGFR_IN_DISEASE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_FGFR_IN_DISEASE AKT3 SPRY2 CDKN1A CDKN1B ADCY1 ADCY2 FRS3 FRS2 ADCY3 CPSF6 CNTRL ADCY5 FGFR1OP ADCY6 ADCY7 ADCY8 CHUK ADCY9 THEM4 CREB1 CUX1 KLB ADRBK1 ADCY4 AKT1 AKT2 FGF1 FGF2 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGF10 FGFR1 FGFR3 FGFR2 FGFR4 FOXO1 FOXO3 PHLPP1 MTOR RICTOR GAB1 FGFR1OP2 FGF20 FGF22 GRB2 GSK3A NR4A1 HRAS ITPR2 ITPR3 KRAS MYO18A MDM2 FOXO4 NRAS PDE1A PDE1B PDPK1 PIK3CA PIK3R1 PLCG1 IL17RD PPP2CA PPP2CB PPP2R1A PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCD PRKCE PRKCG MAPK1 MAPK3 MAP2K1 MAP2K2 BAD PTEN TRIB3 RAF1 BCR RPS6KB2 RPS27A MLST8 SHC1 SOS1 SRC BRAF STAT1 STAT3 STAT5A STAT5B TSC2 RPS27AP11 LOC729120 LOC730418 UBA52 LOC731292 LOC732425 YWHAB ZMYM2 MAPKAP1 CALM1 CALM2 FGF23 CALM3 CAMK4 CASP9 AKT1S1 MKNK1 CBL TRIM24 FGF18 FGF17 KL CDK1 GAB2 FGF19 +REACTOME_HS_GAG_DEGRADATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HS_GAG_DEGRADATION GPC6 HPSE GPC2 GPC4 GPC5 GPC3 GLB1 GPC1 GUSB HSPG2 IDS IDUA AGRN NAGLU HPSE2 SDC1 SDC2 SDC4 SGSH SDC3 +REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE PIKFYVE PIK3R4 MTM1 PIK3C2A PIK3C3 PI4K2B PI4K2A VAC14 INPP4B MTMR2 MTMR4 FIG4 +REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN HRAS KRAS NGF NRAS NTRK1 MAPK1 MAPK3 MAP2K1 MAP2K2 RAF1 RIT2 RIT1 BRAF YWHAB CDK1 +REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT PSMD14 CHEK1 CHEK2 PSMA8 PSME4 ATM PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RPS27A LOC651610 LOC652826 RPS27AP11 UBA52 PSMF1 PSMD6 CDC25A +REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN EGLN2 EGLN3 CREBBP EP300 EPAS1 EPO HIF1A ARNT EGLN1 HIF1AN RPS27A HIF3A TCEB1P3 TCEB1 TCEB2 RPS27AP11 UBA52 UBE2D1 UBE2D2 UBE2D3 VEGFA VHL CA9 CUL2 RBX1 +REACTOME_ACYL_CHAIN_REMODELLING_OF_PC http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACYL_CHAIN_REMODELLING_OF_PC LPCAT3 PLA2G16 MBOAT2 LPCAT4 PLA2G4F PLA2G2D PLA2G4D PLA2G2E PLA2G3 PNPLA8 PLA2G1B PLA2G2A PLA2G4A PLA2G5 LPCAT2 PLA2G2F PLBD1 LPCAT1 PLA2G12A PLA2G6 PLA2G10 PLA2G4C +REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE PIKFYVE SACM1L PIK3R4 ARF1 ARF3 OCRL PIK3C2A PIK3C2G PIK3C3 PI4KA PI4KB PI4K2B PI4K2A VAC14 INPP5E TPTE2 FIG4 +REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS STUB1 STRAP FKBP1A PPP1R15A SMAD2 SMAD3 SMAD4 SMAD7 FURIN UCHL5 PPP1CA PPP1CB PPP1CC PMEPA1 SMURF1 RPS27A SMURF2 TGFB1 TGFBR1 TGFBR2 RPS27AP11 UBA52 LOC731429 XPO1 MTMR4 ZFYVE9 +REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 FGF1 FGF2 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGF10 FGFR2 FGF20 FGF22 FGF23 FGF18 FGF17 +REACTOME_PHOSPHOLIPID_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PHOSPHOLIPID_METABOLISM COL4A3BP LPCAT3 CEPT1 CDS1 PEMT CDIPT AGPAT1 AGPAT2 SPTLC1 NEU3 CHAT PLA2G16 CHKA CHKB MGLL PLD4 DEGS2 ACER1 SLC44A3 MBOAT2 NEU4 SGPP2 AGPAT6 CSNK1G2 PIK3R6 GPAT2 PPM1L ARSK MBOAT1 PHOSPHO1 SGMS2 PIKFYVE PLD6 CERS3 SLC44A5 ARSG SACM1L GPD1L LPIN1 PIP5K1C SLC44A1 PIK3R5 PLD3 PITPNB KDSR LCLAT1 CERS6 LPCAT4 PLA2G4F GALC SUMF2 SGMS1 PLA2G2D GBA INPP5J GLA GLB1 GM2A GPD1 PLA2G4D SUMF1 CERS2 HADHA HADHB HEXA HEXB PLA2G2E PIK3R4 ENPP7 ARSI ACER2 ARSH INPPL1 ARF1 ARF3 ARSA ARSB STS ARSE ARSF ASAH1 ACHE MTM1 NEU1 NEU2 OCRL OSBP PLA2G3 PNPLA8 PCYT1A INPP5K PIK3C2A PIK3C2B PIK3C2G PIK3C3 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PI4KA PI4KB PIP4K2A PLA2G1B PLA2G2A PLA2G4A PLA2G5 PLD1 PLD2 CRLS1 CTSA LPCAT2 ETNK2 PI4K2B AGPAT5 ACER3 PI4K2A ETNK1 SMPD3 SMPD4 VAC14 PRKD1 GPCPD1 PSAP INPP5E ASAH2 SPHK2 AGPAT3 AGPAT4 CHPT1 PNPLA2 SLC44A2 PTEN GPAM GBA2 GBA3 PCYT2 MTMR14 PLA2G2F CERK LPIN3 ASAH2C SMPD1 SMPD2 TAZ LOC729155 LOC731292 UGCG MBOAT7 CERS4 ARSJ PLBD1 LPCAT1 PNPLA3 SLC44A4 PTDSS2 SGPP1 PLA2G12A PIP5K1B PIP4K2B PLA2G6 PLA2G10 GNPAT DGAT2 AGPAT9 PIK3R3 EPT1 DEGS1 PLA2G4C PPAP2A PPAP2C PPAP2B DGAT1 CDS2 MTMR1 INPP4B SYNJ1 SYNJ2 SPHK1 SGPL1 MTMR3 MTMR2 CERS5 MTMR6 MTMR7 MTMR4 VAPB VAPA TPTE2 PCYT1B PGS1 GAL3ST1 SPTLC2 LPIN2 PTDSS1 FIG4 LPGAT1 +REACTOME_CS_DS_DEGRADATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CS_DS_DEGRADATION VCAN NCAN CSPG4 DCN HEXA HEXB HYAL1 IDS IDUA ARSB BGN BCAN +REACTOME_SYNTHESIS_OF_PA http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_PA AGPAT1 AGPAT2 AGPAT6 GPAT2 GPD1L LCLAT1 LPCAT4 PLA2G2D GPD1 PLA2G4D PLA2G2E PLA2G1B PLA2G2A PLA2G4A PLA2G5 PLD1 PLD2 AGPAT5 AGPAT3 AGPAT4 GPAM PLA2G2F LPCAT1 PLA2G12A PLA2G10 GNPAT AGPAT9 +REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA EGLN2 EGLN3 EPAS1 HIF1A EGLN1 RPS27A HIF3A TCEB1P3 TCEB1 TCEB2 RPS27AP11 UBA52 UBE2D1 UBE2D2 UBE2D3 VHL CUL2 RBX1 +REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE PIKFYVE PIK3R4 MTM1 PIK3C2A PIK3C3 VAC14 MTMR2 MTMR7 MTMR4 FIG4 +REACTOME_SYNTHESIS_OF_PE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_PE CEPT1 CHKA CHKB PHOSPHO1 LPIN1 ETNK2 ETNK1 PCYT2 LPIN3 EPT1 LPIN2 +REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK RASGRP1 LPAR6 RASGRP2 RGS19 NMUR1 GNB5 CYSLTR1 NMU NPFFR2 PROKR1 UTS2 CHRM1 CHRM3 CHRM5 MGLL ARHGEF25 LTB4R PROKR2 NMS CREB1 DGKK ADRA1D ADRA1B ADRA1A ADRBK1 DGKA DGKB DGKG DGKH DGKQ AGT HBEGF AGTR1 LPAR1 EDN1 EDN2 EDN3 EDNRA EDNRB EGFR F2 F2R F2RL1 F2RL2 DAGLB GPRC6A PLCB1 LPAR3 FPR2 NTSR2 GAST UTS2D GCG GCGR GHSR P2RY10 GNA11 GNA15 GNAQ GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GNRH1 GNRH2 GNRHR GPR4 XCR1 UTS2R GPR17 LPAR4 MCHR1 MLNR FFAR1 FFAR3 FFAR2 GRK5 GRB2 GRP GRPR GPR132 ANXA1 HCRT HCRTR1 HCRTR2 HRAS HRH1 HTR2A HTR2B HTR2C QRFP APP ITPR2 ITPR3 KISS1 KNG1 KRAS NPSR1 MLN MMP3 RGS21 NMB NMBR NRAS NTS NTSR1 OXT OXTR P2RY1 P2RY2 P2RY6 P2RY11 GHRL GNG13 PIK3CA PIK3R1 PIK3R2 PLCB2 PLCB3 PLCB4 PMCH GNG2 AVP AVPR1A AVPR1B PRKCA PRKCD PRKCE PRKCH PRKCQ MAPK1 MAPK3 GNG12 MAPK7 MAP2K1 MAP2K2 LTB4R2 NMUR2 CYSLTR2 TRPC7 PTAFR PTGER1 PTGFR RAF1 GNB4 NPS RGS2 RPS6KA1 RPS6KA2 RPS6KA3 BDKRB1 BDKRB2 SAA1 XCL1 NPFFR1 RGS18 SOS1 BRS3 XCL2 TAC1 TACR2 TAC3 TACR1 TACR3 TBXA2R TRH TRHR TRIO TRPC3 TRPC6 LOC730221 LOC730335 LOC730413 LOC731823 DAGLA YWHAB GPR68 QRFPR PROK1 MCHR2 CASR KISS1R GPR65 PIK3R3 DGKE DGKD NPFF CCK CCKAR CCKBR KALRN F2RL3 DGKI LPAR2 OPN4 GNG8 GNA14 CDK1 +REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS VCAN NCAN CSPG4 DCN CHST13 CHSY1 CHSY3 CHST11 CHST15 CHPF2 CSGALNACT2 CHST12 CSGALNACT1 CHST7 BGN BCAN LOC644504 LOC644691 CHPF CHST9 CHST3 +REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION LYVE1 GUSB HEXA HEXB HMMR HYAL1 STAB2 SLC9A1 HYAL2 CD44 +REACTOME_SIGNALING_BY_FGFR1_MUTANTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_FGFR1_MUTANTS CPSF6 CNTRL FGFR1OP CUX1 FGF1 FGF2 FGF4 FGF5 FGF6 FGF8 FGF9 FGFR1 FGFR1OP2 FGF20 GRB2 MYO18A PIK3CA PIK3R1 PLCG1 BCR STAT1 STAT3 STAT5A STAT5B LOC732425 ZMYM2 FGF23 TRIM24 FGF17 GAB2 +REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE PIK3R6 PIP5K1C PIK3R5 INPP5J INPPL1 MTM1 INPP5K PIK3C2A PIK3C2B PIK3C2G PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIP4K2A PI4K2B PI4K2A PTEN MTMR14 LOC731292 PIP5K1B PIP4K2B PIK3R3 MTMR1 INPP4B SYNJ1 SYNJ2 MTMR3 MTMR6 +REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES ARSK ARSG SUMF2 SUMF1 ARSI ARSH ARSA ARSB STS ARSE ARSF ARSJ +REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER CDK8 CDK9 CDKN2B PARP1 E2F4 E2F5 WWTR1 HDAC1 JUNB SMAD2 SMAD3 SMAD4 SMAD7 MEN1 LOC441488 MYC SERPINE1 TRIM33 PPM1A RBL1 TGIF2 RPS27A SMURF2 SKI SKIL SP1 TFDP1 TGIF1 RPS27AP11 UBA52 UBE2D1 UBE2D3 USP9X CCNC CCNT1 CCNT2 NCOR1 NCOR2 +REACTOME_HYALURONAN_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HYALURONAN_METABOLISM ABCC5 LYVE1 GUSB HAS1 HAS2 HAS3 HEXA HEXB HMMR HYAL1 STAB2 SLC9A1 HYAL2 CD44 +REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY PARP1 HDAC1 SMAD2 SMAD3 SMAD4 TRIM33 PPM1A TGIF2 RPS27A SMURF2 SKI SKIL TGIF1 RPS27AP11 UBA52 UBE2D1 UBE2D3 USP9X NCOR1 NCOR2 +REACTOME_KERATAN_SULFATE_BIOSYNTHESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_KERATAN_SULFATE_BIOSYNTHESIS B3GNT3 ST3GAL6 B3GNT2 B3GNT1 KERA ACAN FMOD CHST5 B4GALT1 LUM CHST6 OMD OGN PRELP ST3GAL1 ST3GAL2 ST3GAL3 B3GNT4 CHST1 B4GALT4 B4GALT3 B4GALT2 B3GNT7 B4GALT6 B4GALT5 CHST2 +REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE CA5B CA14 CA13 CA1 CA2 CA3 CA4 CA5A CA6 CA7 CA9 CA12 +REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS CPSF6 CNTRL FGFR1OP CUX1 FGFR1OP2 GRB2 MYO18A PIK3CA PIK3R1 PLCG1 BCR STAT1 STAT3 STAT5A STAT5B LOC732425 ZMYM2 TRIM24 GAB2 +REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM ACOT8 ABCD1 ACSL1 ACAA1 HSD17B4 FADS1 ACOX1 ELOVL2 ELOVL5 SCP2 ABCD1P5 FADS2 +REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 FGF1 FGF2 FGF4 FGF5 FGF6 FGF8 FGF9 FGFR1 FGF20 FGF23 FGF17 +REACTOME_PI_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PI_METABOLISM PIK3R6 PIKFYVE SACM1L PIP5K1C PIK3R5 PITPNB INPP5J PIK3R4 INPPL1 ARF1 ARF3 MTM1 OCRL INPP5K PIK3C2A PIK3C2B PIK3C2G PIK3C3 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PI4KA PI4KB PIP4K2A PI4K2B PI4K2A VAC14 INPP5E PTEN MTMR14 LOC731292 PIP5K1B PIP4K2B PIK3R3 MTMR1 INPP4B SYNJ1 SYNJ2 MTMR3 MTMR2 MTMR6 MTMR7 MTMR4 TPTE2 FIG4 +REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM ADH1A ADAL NT5C2 GUK1 PCK1 ABCB1 SLC22A1 SLC22A3 SLC22A2 ABCG2 +REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM GPC6 UST B4GALT7 CHST14 B3GALT6 B3GAT2 VCAN NCAN CSPG4 DCN CHST13 GPC2 GPC4 GPC5 CHSY1 B3GAT3 B3GAT1 GPC3 GPC1 GXYLT1 DSE HEXA HEXB HSPG2 HYAL1 CHSY3 IDS IDUA AGRN ARSB CHST11 CHST15 CHPF2 CSGALNACT2 CHST12 CSGALNACT1 CHST7 BGN SDC1 BCAN SDC2 SDC4 LOC644504 LOC644691 GXYLT2 CHPF CHST9 CHST3 SDC3 +REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS TCIRG1 ATP6V1G3 CYBA CYBB ATP6V0A2 ATP6V0D2 ATP6V1C2 LTF NCF2 NCF4 NOS1 NOS2 NOS3 ATP6V0A4 ATP6V1D ATP6V1H ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V0C ATP6V1C1 ATP6V1E1 ATP6V0B ATP6V1G2 LOC648998 SLC11A1 LOC728320 CAMP ATP6V0E1 ATP6V1E2 ATP6V0D1 ATP6V1F ATP6V1G1 +REACTOME_SYNTHESIS_OF_PC http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_PC CEPT1 PEMT CHAT CHKA CHKB SLC44A3 PHOSPHO1 SLC44A5 LPIN1 SLC44A1 ACHE PCYT1A CHPT1 SLC44A2 LPIN3 SLC44A4 PCYT1B LPIN2 +REACTOME_HS_GAG_BIOSYNTHESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HS_GAG_BIOSYNTHESIS GPC6 EXT1 EXT2 GPC2 HS3ST5 GPC4 GPC5 GLCE HS6ST3 GPC3 GPC1 HSPG2 NDST1 AGRN SDC1 SDC2 SDC4 NDST4 HS3ST6 HS6ST1P1 NDST2 HS6ST2 NDST3 HS6ST1 HS2ST1 SDC3 HS3ST4 HS3ST3B1 HS3ST3A1 HS3ST2 HS3ST1 +REACTOME_SIGNALING_BY_FGFR3_MUTANTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_FGFR3_MUTANTS FGF1 FGF2 FGF4 FGF5 FGF8 FGF9 FGFR3 FGF20 FGF23 FGF18 FGF17 +REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM B3GNT3 ST3GAL6 B3GNT2 B3GNT1 KERA ACAN FMOD CHST5 B4GALT1 GLB1 GNS HEXA HEXB LUM CHST6 OMD OGN PRELP ST3GAL1 ST3GAL2 ST3GAL3 B3GNT4 CHST1 B4GALT4 B4GALT3 B4GALT2 B3GNT7 B4GALT6 B4GALT5 CHST2 +REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION DFFA DFFB H1F0 HIST1H1C HIST1H1D HIST1H1E HIST1H1B HIST1H1A HMGB1 HMGB2 KPNA1 KPNB1 CASP3 +REACTOME_KERATAN_SULFATE_DEGRADATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_KERATAN_SULFATE_DEGRADATION KERA ACAN FMOD GLB1 GNS HEXA HEXB LUM OMD OGN PRELP +REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM GPC6 HPSE B4GALT7 B3GALT6 B3GAT2 VCAN NCAN CSPG4 DCN EXT1 EXT2 GPC2 HS3ST5 GPC4 GPC5 GLCE B3GAT3 HS6ST3 B3GAT1 GPC3 GLB1 GPC1 GXYLT1 GUSB HSPG2 NDST1 IDS IDUA AGRN NAGLU HPSE2 BGN SDC1 BCAN SDC2 SDC4 SGSH NDST4 HS3ST6 GXYLT2 HS6ST1P1 NDST2 HS6ST2 NDST3 HS6ST1 HS2ST1 SDC3 HS3ST4 HS3ST3B1 HS3ST3A1 HS3ST2 HS3ST1 +REACTOME_GLYCOSAMINOGLYCAN_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLYCOSAMINOGLYCAN_METABOLISM ABCC5 GPC6 UST B3GNT3 ST3GAL6 B3GNT2 HPSE LYVE1 B3GNT1 KERA B4GALT7 CHST14 B3GALT6 B3GAT2 VCAN NCAN CSPG4 DCN CHST13 ACAN EXT1 EXT2 GPC2 HS3ST5 GPC4 GPC5 CHSY1 FMOD CHST5 GLCE B3GAT3 HS6ST3 B4GALT1 B3GAT1 GPC3 GLB1 GNS GPC1 GXYLT1 GUSB DSE HAS1 HAS2 HAS3 HEXA HEXB HMMR HSPG2 NDST1 HYAL1 CHSY3 IDS IDUA AGRN LUM ARSB CHST6 NAGLU OMD OGN CHST11 CHST15 CHPF2 CSGALNACT2 PRELP CHST12 STAB2 CSGALNACT1 CHST7 HPSE2 BGN SDC1 BCAN SDC2 SDC4 LOC644504 LOC644691 SGSH NDST4 HS3ST6 ST3GAL1 ST3GAL2 ST3GAL3 SLC9A1 GXYLT2 HS6ST1P1 B3GNT4 CHPF CHST9 NDST2 CHST1 HYAL2 B4GALT4 B4GALT3 B4GALT2 HS6ST2 B3GNT7 B4GALT6 B4GALT5 NDST3 HS6ST1 CHST2 CHST3 CD44 HS2ST1 SDC3 HS3ST4 HS3ST3B1 HS3ST3A1 HS3ST2 HS3ST1 +REACTOME_ACYL_CHAIN_REMODELLING_OF_PG http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACYL_CHAIN_REMODELLING_OF_PG LPCAT4 PLA2G4F PLA2G2D PLA2G4D PLA2G2E PLA2G3 PLA2G1B PLA2G2A PLA2G4A PLA2G5 CRLS1 PLA2G2F LPCAT1 PLA2G12A PLA2G10 LPGAT1 +REACTOME_ACYL_CHAIN_REMODELLING_OF_PE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACYL_CHAIN_REMODELLING_OF_PE LPCAT3 PLA2G16 MBOAT2 MBOAT1 LPCAT4 PLA2G4F PLA2G2D PLA2G4D PLA2G2E PLA2G3 PNPLA8 PLA2G1B PLA2G2A PLA2G4A PLA2G5 PLA2G2F PLBD1 PLA2G12A PLA2G6 PLA2G10 PLA2G4C +REACTOME_ACYL_CHAIN_REMODELLING_OF_PS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACYL_CHAIN_REMODELLING_OF_PS LPCAT3 PLA2G16 MBOAT1 LPCAT4 PLA2G4F PLA2G2D PLA2G4D PLA2G2E PLA2G1B PLA2G2A PLA2G4A PLA2G5 PLA2G2F PLA2G12A PLA2G10 +REACTOME_SIGNALING_BY_FGFR_MUTANTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_FGFR_MUTANTS FRS2 CPSF6 CNTRL FGFR1OP CUX1 FGF1 FGF2 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGF10 FGFR1 FGFR3 FGFR2 FGFR4 GAB1 FGFR1OP2 FGF20 FGF22 GRB2 HRAS KRAS MYO18A NRAS PIK3CA PIK3R1 PLCG1 BCR SOS1 STAT1 STAT3 STAT5A STAT5B LOC732425 ZMYM2 FGF23 TRIM24 FGF18 FGF17 GAB2 +REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION AP1M2 KIF20A ACTR1B ACTR1A SEC24B SEC23A DCTN2 DCTN6 CTSC KIF2C DCTN3 OSBPL1A AP2M1 AP1S1 AP2S1 CLTA CLTC DYNLL2 KLC3 CTSB CTSD CTSH CTSK CTSL1 CTSL2 CTSO CTSS AP2A1 AP2A2 AP1B1 AP2B1 DCTN1 AP1G1 DNM1 DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI2 DNM2 SEC31A KIFAP3 KIF4A KIF26A KIF4B RACGAP1 HLA-DMA HLA-DMB HLA-DOA HLA-DOB HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DRB1 HLA-DRB3 HLA-DRB5 ARF1 KIF2A KIF3C KIF5A KIF5B KLC1 KIF11 KIF22 SAR1B DCTN4 DYNC2LI1 CTSA LGMN KIF15 SEC13 SH3GL2 KLC2 SPTBN2 RAB7A DYNC2H1 KIF18A CANX RILP DCTN5 KIF2B DYNLL1 CTSF AP1S2 AP1M1 KLC4 KIF3B KIF23 SEC24C CD74 SEC24D +REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS LPCAT3 CEPT1 CDS1 PEMT CDIPT AGPAT1 AGPAT2 CHAT PLA2G16 CHKA CHKB MGLL PLD4 SLC44A3 MBOAT2 AGPAT6 GPAT2 MBOAT1 PHOSPHO1 PLD6 SLC44A5 GPD1L LPIN1 SLC44A1 PLD3 PITPNB LCLAT1 LPCAT4 PLA2G4F PLA2G2D GPD1 PLA2G4D HADHA HADHB PLA2G2E ACHE PLA2G3 PNPLA8 PCYT1A PLA2G1B PLA2G2A PLA2G4A PLA2G5 PLD1 PLD2 CRLS1 LPCAT2 ETNK2 AGPAT5 ETNK1 GPCPD1 AGPAT3 AGPAT4 CHPT1 PNPLA2 SLC44A2 GPAM PCYT2 PLA2G2F LPIN3 TAZ MBOAT7 PLBD1 LPCAT1 PNPLA3 SLC44A4 PTDSS2 PLA2G12A PLA2G6 PLA2G10 GNPAT DGAT2 AGPAT9 EPT1 PLA2G4C DGAT1 CDS2 PCYT1B PGS1 LPIN2 PTDSS1 LPGAT1 +REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS GPC6 B4GALT7 B3GALT6 B3GAT2 VCAN NCAN CSPG4 DCN GPC2 GPC4 GPC5 B3GAT3 B3GAT1 GPC3 GPC1 GXYLT1 HSPG2 AGRN BGN SDC1 BCAN SDC2 SDC4 GXYLT2 SDC3 +REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6 CDK2 PSMD14 PSMA8 PSME4 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RPS27A LOC652826 RPS27AP11 UBA52 PSMF1 PSMD6 CDC6 +REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN COL1A1 COL1A2 FCER1G FYN GP1BA GP1BB GP5 GP9 ITGA2 ITGB1 LYN VWF +REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS FIGF FLT1 FLT4 KDR PDGFC VEGFA VEGFB VEGFC NRP2 NRP1 +REACTOME_ENOS_ACTIVATION_AND_REGULATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ENOS_ACTIVATION_AND_REGULATION LYPLA1 NOSTRIN DHFR DNM2 AKT1 GCH1 GCHFR HSP90AA1 ZDHHC21 NOS3 NOSIP PRKG2 PTS DHFRP1 SPR CALM1 CALM2 CALM3 CAV1 WASL +REACTOME_MICRORNA_MIRNA_BIOGENESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MICRORNA_MIRNA_BIOGENESIS EIF2C3 EIF2C4 DICER1 EIF2C1 EIF2C2 DROSHA POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L DGCR8 XPO5 RAN LOC643631 TARBP2 +REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION CREB1 MAPK14 DUSP3 DUSP4 DUSP6 DUSP7 ELK1 MEF2A MEF2C ATF1 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D MAPK1 MAPK3 MAPK7 MAPK11 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA5 MAPKAPK2 +REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING DNAL4 AP2M1 AP2S1 CLTA CLTC AP2A1 AP2A2 AP2B1 DNM1 DNM2 NGF NTRK1 SH3GL2 +REACTOME_ERKS_ARE_INACTIVATED http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ERKS_ARE_INACTIVATED DUSP3 DUSP4 DUSP6 DUSP7 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D MAPK1 MAPK3 MAPK7 +REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK AKT3 THEM4 AKT1 AKT2 PHLPP1 PTEN TRIB3 LOC729120 LOC731292 +REACTOME_PI3K_AKT_ACTIVATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PI3K_AKT_ACTIVATION AKT3 CDKN1A CDKN1B CHUK THEM4 CREB1 AKT1 AKT2 FOXO1 FOXO3 PHLPP1 MTOR RICTOR GSK3A NR4A1 IRS1 RHOA MDM2 FOXO4 NGF NTRK1 PDPK1 PIK3CA PIK3CB PIK3R1 PIK3R2 BAD PTEN TRIB3 RPS6KB2 MLST8 TSC2 LOC729120 LOC731292 MAPKAP1 CASP9 AKT1S1 IRS2 +REACTOME_REGULATORY_RNA_PATHWAYS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATORY_RNA_PATHWAYS EIF2C3 EIF2C4 TNRC6B DICER1 EIF2C1 EIF2C2 TNRC6A DROSHA POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L DGCR8 XPO5 TNRC6C RAN LOC643631 TARBP2 +REACTOME_EGFR_DOWNREGULATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_EGFR_DOWNREGULATION SPRY1 SPRY2 STAM2 AP2M1 AP2S1 CLTA CLTC AP2A1 AP2A2 AP2B1 EGF EGFR EPS15 GRB2 EPN1 SH3KBP1 EPS15L1 RPS27A SH3GL2 RPS27AP11 UBA52 STAM CBL HGS CDC42 +REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA RBM5 THOC4 HNRNPR SRRM1 SF3B4 SF3A1 CD2BP2 NXF1 PRPF8 NUP50 TXNL4A PAPOLA RNPS1 SF3A3 HNRNPA0 CLP1 SF3B2 NUDT21 NUPL2 HNRNPUL1 U2AF2 SNRPD2P1 NUP35 CSTF1 CSTF2 CSTF3 DHX9 EIF4E HNRNPA3 DNAJC8 NCBP2 SNRNP200 NUP205 NUP210 SF3B3 SF3B1 NUP188 NUP62 PRPF6 FUS RBMX GTF2F1 GTF2F2 CPSF1 HNRNPA1 HNRNPA2B1 HNRNPC HNRNPD HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPL HNRNPU NUP43 MAGOH HNRNPM NCBP1 NFX1 NHP2L1 YBX1 NUP88 PCBP1 PCBP2 CDC40 PCF11 SF3B14 CPSF3 NUP54 CPSF2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L NUP133 CCAR1 METTL3 NUP107 PTBP1 SUGP1 LSM2 RANBP2 SRSF1 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 LOC643446 UPF3B LOC652147 LOC653889 SNRNP70 SNRPA SNRPA1 SNRPB SNRPB2 SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG TPR U2AF1 SLBP NUP37 CPSF7 NUP85 NUP214 AAAS PABPN1 SF3A2 SEH1L SMC1A SF3B5 RAE1 PHF5A SRSF9 PRPF4 SRSF11 EFTUD2 SNRNP40 DDX23 NUP155 NUP93 DHX38 NUPL1 POM121 RBM8A NUP153 +REACTOME_PECAM1_INTERACTIONS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PECAM1_INTERACTIONS FYN ITGAV ITGB3 LCK LYN PECAM1 PLCG1 PTPN6 SRC YES1 +REACTOME_TCR_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TCR_SIGNALING MALT1 CHUK CSK TAB2 FYB LAT HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DRB1 HLA-DRB3 HLA-DRB5 IKBKB ITK TMEM189-UBE2V1 LCK LCP2 NCK1 NFKBIA PAK1 PAK2 TRAT1 EVL PDPK1 PIK3CA PIK3CB PIK3R1 PIK3R2 PLCG1 ENAH PAG1 PRKCQ PTEN PTPRC RELA LOC646626 MAP3K7 TRAF6 LOC731292 UBE2N VASP WAS ZAP70 CARD11 IKBKG RIPK2 BCL10 CD3D CD3E CD3G CD247 CD4 GRAP2 +REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX DLAT DLD PDHA1 PDHB PDK1 PDK2 PDK3 PDK4 PDP1 PDPR PDP2 LOC650883 PDHX +REACTOME_DOWNSTREAM_TCR_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DOWNSTREAM_TCR_SIGNALING MALT1 CHUK TAB2 HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DRB1 HLA-DRB3 HLA-DRB5 IKBKB TMEM189-UBE2V1 LCK NFKBIA TRAT1 PDPK1 PIK3CA PIK3CB PIK3R1 PIK3R2 PRKCQ PTEN RELA LOC646626 MAP3K7 TRAF6 LOC731292 UBE2N CARD11 IKBKG RIPK2 BCL10 CD3D CD3E CD3G CD247 CD4 +REACTOME_BASIGIN_INTERACTIONS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BASIGIN_INTERACTIONS SLC7A9 LOC128192 LOC131691 SLC7A8 SLC16A8 SLC7A11 PPIL2 PPIAP8 ITGA3 ITGB1 L1CAM MAG MMP1 ATP1B1 ATP1B2 ATP1B3 PPIA SLC7A10 LOC643997 SLC3A2 PPIAP22 LOC654188 SLC16A1 SPN BSG SLC7A5 CAV1 SLC7A7 SLC7A6 SLC16A3 +REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL AKT3 CDKN1A CDKN1B CHUK AKT1 AKT2 GSK3A MDM2 BAD TSC2 CASP9 AKT1S1 +REACTOME_GAB1_SIGNALOSOME http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GAB1_SIGNALOSOME AKT3 CDKN1A CDKN1B CHUK THEM4 CREB1 CSK EGF EGFR AKT1 AKT2 FOXO1 FOXO3 PHLPP1 MTOR RICTOR GAB1 GRB2 GSK3A NR4A1 MDM2 FOXO4 PDPK1 PIK3CA PIK3R1 PAG1 BAD PTEN TRIB3 RPS6KB2 MLST8 SRC TSC2 LOC729120 LOC731292 MAPKAP1 CASP9 AKT1S1 +REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING EGF EGFR GRB2 HRAS KRAS NRAS MAPK1 MAPK3 MAP2K1 MAP2K2 RAF1 SHC1 SOS1 YWHAB CDK1 +REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S EIF1AX EIF2S1 EIF2S3 EIF4A1 EIF4A2 EIF4B EIF4E EIF4EBP1 EIF4G1 FAU PABPC1 EIF3K EIF3FP3 EIF3E RPSAP12 RPS8P10 RPS12P4 RPSA RPS26P10 RPS12P22 RPS26P35 RPS2 RPS3 RPS3A RPS4X RPS4Y1 RPS5 RPS6 RPS7 RPS8 RPS9 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS18 RPS19 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS28 RPS29 RPS29P3 RPS26P28 RPS26P20 RPS15AP11 RPS26P50 RPS13P8 RPS28P4 RPS28P7 RPS28P9 LOC651894 LOC652607 RPSAP9 LOC653994 RPS27AP11 RPS26P7 RPS26P25 RPS19P3 RPS18P10 RPS15P5 RPS10P9 RPS18P5 EIF4H EIF3A EIF3B EIF3C EIF3D EIF3F EIF3G EIF3H EIF3I EIF3J EIF2S2 +REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS CSK HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DRB1 HLA-DRB3 HLA-DRB5 LCK PAG1 PTPRC CD3D CD3E CD3G CD247 CD4 +REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE UNC13B RIMS1 GLS2 GLS SLC38A2 SLC17A7 RAB3A SLC1A1 SLC1A6 SLC1A7 SNAP25 STX1A STXBP1 VAMP2 SYT1 +REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DRB1 HLA-DRB3 HLA-DRB5 LCK ZAP70 CD3D CD3E CD3G CD247 CD4 +REACTOME_ERK_MAPK_TARGETS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ERK_MAPK_TARGETS MAPK14 DUSP3 DUSP4 DUSP6 DUSP7 ELK1 MEF2A MEF2C PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D MAPK1 MAPK3 MAPK7 MAPK11 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA5 +REACTOME_TIE2_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TIE2_SIGNALING ANGPT1 ANGPT2 GRB2 GRB7 GRB14 HRAS KRAS NRAS ANGPT4 PIK3CA PIK3CB PIK3R1 PIK3R2 SHC1 SOS1 TEK DOK2 +REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES FYB LAT HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DRB1 HLA-DRB3 HLA-DRB5 ITK LCK LCP2 NCK1 PAK1 PAK2 EVL PLCG1 ENAH VASP WAS ZAP70 CD3D CD3E CD3G CD247 CD4 GRAP2 +REACTOME_GENERIC_TRANSCRIPTION_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GENERIC_TRANSCRIPTION_PATHWAY MED6 NR2E3 MED16 MAMLD1 NR1H3 ZNF263 TRIM28 ZNF197 ZNF256 ZNF443 CDK8 CDK9 CDKN2B ZNF267 YAP1 NCOA2 ZNF211 ZNF234 ZNF266 ZNF274 ZNF273 ZNF460 MED8 ZIM3 ZNF354B ZNF641 ZNF543 ZNF441 ZNF440 NR2C2AP CREBBP ZFP28 PARP1 ZFP90 ZNF597 ZNF480 ZNF418 ZNF417 ZNF548 ZNF560 ZNF563 ZNF420 ZNF565 ZNF582 ZNF583 ZNF599 ZNF558 ZNF98 ZNF555 ZNF569 ZNF570 CTGF ZNF595 ZNF425 ZNF483 ZFP1 ZNF519 ZNF610 ZNF600 ZNF320 ZNF564 ZNF433 ZNF114 ZNF567 ZNF383 ZNF100 ZNF540 ZNF92 ZNF596 ZNF169 ZNF431 E2F4 E2F5 NR0B1 ZNF627 ZNF585A ZNF584 NR2F6 ESR1 ESR2 ESRRA ESRRB ESRRG ZNF25 ZNF485 ZNF498 ZNF510 SNW1 NCOA6 ZIM2 ZKSCAN5 NR5A2 NR5A1 ZNF620 ZNF324 ZNF473 WWTR1 ZNF500 ZNF658 ZNF337 KAT2A NR6A1 ZNF285 ZNF544 ZNF311 ZNF547 ZIK1 ZNF615 ZNF493 ZNF619 ZNF621 ZNF454 MED4 NR3C1 NRBP1 NRBF2 HDAC1 ZNF354C NR4A1 HNF4A HNF4G ZNF546 ZNF642 ZNF517 ZNF530 RBPJ ZNF445 AR JUNB ZNF773 ZKSCAN4 ZNF658B SMAD2 SMAD3 SMAD4 SMAD7 MEN1 NR3C2 ZNF506 LOC441488 ZNF806 MYC NOTCH2 NOTCH3 NOTCH4 NPPA NR4A2 SERPINE1 MED31 ZNF571 ZNF589 MED15 TRIM33 PGR PPARA PPARD PPARG MED1 ZNF434 PPM1A ZNF331 MAML3 ZNF416 ZNF446 ZNF334 ZNF415 ZNF167 ZNF248 ZNF286A ZNF287 ZNF304 ZNF490 ZNF398 ZNF624 ZNF471 ZNF492 ZNF317 ZNF529 ZNF250 RARA RARG RBL1 ZNF350 TGIF2 RORA RORB RORC RPS27A RXRA RXRB RXRG SMURF2 SKI SKIL ZNF643 ZNF649 SMARCD3 SP1 TBL1X TBX5 ZNF354A TEAD1 TEAD4 TEAD3 NR2F1 TFDP1 TGIF1 THRA THRB NR2E1 LOC728030 LOC728381 RPS27AP11 LOC100288042 UBA52 LOC731106 LOC731863 UBE2D1 UBE2D3 LOC100287908 NR1H2 VDR ZFP37 ZNF2 ZNF3 ZNF10 ZNF12 ZNF14 ZNF708 ZNF17 ZNF18 ZNF19 ZNF20 ZNF23 ZNF26 ZNF28 ZNF33A ZNF33B ZKSCAN1 ZNF37A ZNF43 ZNF45 ZNF221 ZNF222 ZNF136 ZNF138 ZNF140 ZNF141 ZNF154 ZNF155 ZNF157 ZNF175 ZNF180 ZNF184 ZNF189 ZNF192 ZNF200 ZNF202 ZNF205 ZNF208 ZNF213 ZNF214 ZNF215 ZNF223 ZNF224 ZNF225 ZNF226 ZNF227 ZFP112 ZNF230 ZNF655 ZNF426 ZNF343 ZNF557 TBL1XR1 ZNF419 ZNF552 ZNF212 ZNF613 ZNF442 ZNF556 ZNF606 ZFP2 ZNF614 NR4A3 ZNF430 ZKSCAN3 ZNF436 ZNF611 MED25 NCOA3 USP9X ZNF484 ZNF394 MED10 ZNF282 NR0B2 ZNF528 MAML2 ZNF333 ZNF559 TEAD2 ZNF347 ZNF577 ZNF607 ZNF496 ZNF514 ZNF382 ZNF587 ZNF566 PRIC285 RUNX2 NCOA1 KAT2B NR1I2 CCNC ZNF30 ZNF551 ZNF616 ZNF468 ZNF160 MED30 CCNT1 ZNF605 CCNT2 ZNF625 ZNF439 ZNF479 ZNF300 ZNF585B MED14 ZNF235 ZNF561 ZNF101 ZNF264 MED23 MED17 MED26 MED27 MED7 MED20 ZNF254 NR1D1 NCOR1 NCOR2 ZNF432 TGS1 MAML1 MED24 MED12 NR1I3 NR1D2 +REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ ABCC4 CAP1 CFL1 CLU LOC128192 LOC131691 CFD EGF A2M ALB F5 F8 F13A1 FGA FGB ALDOA FGG FIGF MMRN1 HABP4 FN1 BRPF3 SCG3 HGF HRG HSPA5 APOA1 PPIAP8 APP ITGA2B ITGB3 KNG1 LAMP2 SERPINE1 PDGFA PDGFB PECAM1 PF4 PFN1 SERPINA1 PLG PLEK SERPINF2 PPBP PPIA SRGN PRKCA PRKCB PRKCG PROS1 PSAP SELP POTEM LOC643997 LOC652612 PPIAP22 LOC654188 SOD1 SPARC STX4 STXBP3 TF TGFB1 TGFB2 TGFB3 LEFTY2 THBS1 TIMP1 TLN1 SERPING1 TMSB4X TUBA4A LOC727848 VCL VEGFA VEGFB VEGFC VWF CALM1 CALM2 CALM3 ACTN4 CALU ACTN1 ACTN2 CD9 CD36 CD63 WDR1 +REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM THOC4 SRRM1 NXF1 NUP50 RNPS1 NUPL2 U2AF2 NUP35 EIF4E NCBP2 NUP205 NUP210 NUP188 NUP62 CPSF1 NUP43 MAGOH NCBP1 NFX1 NUP88 CDC40 CPSF3 NUP54 CPSF2 NUP133 NUP107 RANBP2 SRSF1 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 LOC643446 UPF3B TPR U2AF1 SLBP NUP37 NUP85 NUP214 AAAS SEH1L RAE1 SRSF9 SRSF11 NUP155 NUP93 DHX38 NUPL1 POM121 RBM8A NUP153 +REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES AASS SLC25A15 PSMD14 CDO1 CGA CGB FTCD HIBADH ADC CKB CKM CKMT1B CKMT2 TPH2 AFMID ACMSD UROC1 CPS1 PSMA8 AMDHD1 SLC25A10 CTH AANAT DAO DBH NAGS DBT DDC IDO2 NQO1 DIO1 DIO2 DIO3 DLD DLST AGXT AHCY PAOX FAH ALDH9A1 PSME4 ETHE1 HAAO FSHB GAMT AMD1 PHGDH HIBCH GATM GCDH ACAD8 GLS2 GCLC GCLM MAT2B GLS GLUD1 GLUL GOT1 GOT2 GPT GSTZ1 PSAT1 HSD17B10 HAL HDC HGD HPD ACADSB IDO1 INHA INHBA INHBB INHBC IVD ACAT1 ARG1 ARG2 IYD LHB MAT1A MAT2A ALDH6A1 ASL ASNS ASS1 MTAP MTR OAT OAZ1 OAZ2 ODC1 OGDH OTC ALDH7A1 PAH PCBD1 APIP AADAT PCSK1 CSAD AZIN1 OAZ3 PNMT HAO1 POMC SMOX CKMT1A AUH TMLHE ADI1 CNDP2 PRODH CCBL2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 MCCC1 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 PSPH PYCR1 ALDH18A1 SQRDL ENOPH1 BCAT1 QDPR BCAT2 BCKDHA BCKDHB SAT1 BHMT MCCC2 LOC643554 SHMT1 LOC648605 AGXT2 SLC5A5 LOC652826 SLC6A8 SMS SRM SUOX TAT TDO2 TH TPH1 TPO TSHB TST LOC731026 AGMAT INHBE SLC25A2 BBOX1 MRI1 GPT2 KMO ALDH4A1 CBS CCBL1 KYNU SLC25A21 CGB5 GRHPR CGB8 PSMF1 PSMD6 +REACTOME_RNA_POL_I_TRANSCRIPTION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_I_TRANSCRIPTION CDK7 EHMT2 CBX3 HIST4H4 HIST2H3C HIST3H2BB ERCC2 ERCC3 ERCC6 HIST1H2BA POLR1A PTRF GTF2H1 GTF2H2 GTF2H3 GTF2H4 HIST1H2AE HIST1H2AD H2AFX H2AFZ HIST1H2BD HIST1H2BB H3F3A H3F3B HIST2H3A H3F3AP5 MNAT1 POLR1D POLR2H POLR2K RRN3 HIST2H4B MAPK3 H3F3AP6 LOC652857 GTF2H2B HIST2H3D LOC653972 HIST2H2AA4 LOC731820 UBTF HIST1H4I HIST1H2AJ HIST1H2AC HIST1H2AB HIST2H2AA3 HIST2H2AC HIST1H2BG HIST1H2BL HIST1H2BN HIST1H2BM HIST1H2BF HIST1H2BE HIST1H2BH HIST1H2BI HIST1H2BC HIST1H2BO HIST2H2BE HIST1H3A HIST1H3D HIST1H3C HIST1H3E HIST1H3I HIST1H3G HIST1H3J HIST1H3H HIST1H3B HIST1H4A HIST1H4D HIST1H4F HIST1H4K HIST1H4J HIST1H4C HIST1H4H HIST1H4B HIST1H4E HIST1H4L HIST2H4A POLR1B HIST1H2BK KAT2B MBD2 HIST1H3F HIST1H2BJ TAF1C TAF1B TAF1A CCNH POLR1C +REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS ACSL1 ACSL3 ACSL4 FASN ACSL6 ACACA ACLY HSD17B12 ACSL5 ELOVL2 ELOVL5 ELOVL1 SLC25A1 ELOVL4 ELOVL6 ELOVL7 ELOVL3 TECR +REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION ORC6 ORC3 ORC1 ORC2 ORC4 ORC5 MCM8 CCNB1 CDK1 CDC25A +REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES IKBKB IRAK1 MYD88 NGF NGFR PRKCI RPS27A TRAF6 RPS27AP11 UBA52 RIPK2 SQSTM1 +REACTOME_BIOLOGICAL_OXIDATIONS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BIOLOGICAL_OXIDATIONS NAT2 GLYAT BPNT1 UGT2B11 CYP46A1 UGT2A1 CYP4F8 CYP2U1 ACSM1 GSTO2 CYP2R1 ADH1A ADH1B ADH1C ADH4 ADH6 ADH7 COMT CYP1A1 CYP1A2 CYP1B1 CYP2A6 CYP3A7 CYP2A13 CYP2B6 CYP2C19 CYP2C8 CYP2C9 CYP2C18 CYP2D6 CYP2E1 CYP2F1 CYP2J2 CYP3A4 CYP3A5 CYP4A11 CYP4B1 CYP7A1 CYP8B1 CYP11A1 CYP11B1 CYP11B2 CYP17A1 CYP19A1 CYP21A2 CYP24A1 CYP26A1 CYP27A1 CYP27B1 CYP51A1 AHCY PAOX ALDH1A1 ALDH2 GSTA5 SLC35D1 FMO1 FMO2 FMO3 SULT4A1 GGT1 GGT7 GGT5 OPLAH SULT1C4 SULT1B1 GCLC GCLM MAT2B GSS GSTA1 GSTA2 GSTA3 GSTA4 GSTM1 GSTM4 GSTM5 GSTP1 CYP2S1 CYP26C1 ACSM2B CYP4F3 MAOA MAOB MAT1A MAT2A MGST1 MGST2 MGST3 SULT1A4 MTR NNMT CYP39A1 POMC UGT2B28 SMOX UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9 UGT1A4 UGT1A1 UGT1A3 CYP2W1 CNDP2 ACSS2 CYP26B1 PTGIS PTGS1 PTGS2 CYP4F11 CYP3A43 LOC648338 CYP4F12 SULT1E1 SULT1A2 SULT1A1 SULT1A3 SULT1C2 SULT2B1 SULT2A1 TBXAS1 TPMT LOC731992 UGDH UGP2 UGT2B4 UGT2B7 UGT2B10 UGT2B17 GGCT ACSS1 CYP4F2 NAT1 PAPSS2 PAPSS1 CYP7B1 GSTO1 +REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR NCSTN NGFR APH1A PSENEN PSEN1 PSEN2 RELA ADAM17 TRAF6 APH1B +REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES AKAP9 CACNG3 CACNG2 UNC13B GNB5 ADCY1 ADCY2 ADCY3 CHAT ADCY5 ADCY6 ADCY7 CHRNA1 CHRNA2 CHRNA3 CHRNA4 CHRNA5 CHRNA7 ADCY8 CHRNB2 CHRNB3 CHRNB4 CHRND CHRNE CHRNG ADCY9 AP2M1 AP2S1 COMT CREB1 SLC32A1 AP2A1 AP2A2 AP2B1 DLG1 DLG3 ABAT ADCY4 EPB41L1 ALDH2 RIMS1 ARHGEF9 PLCB1 GABBR1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRG2 GABRG3 GABRR1 GABRR2 GAD1 GAD2 CACNG4 GLS2 RPS6KA6 GLS GLUL GNAI1 GNAI2 GNAI3 GNAL GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GRIA1 GRIA2 GRIA3 GRIA4 GRIK1 GRIK2 GRIK3 GRIK4 GRIK5 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D HRAS HSPA8 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6 KCNJ9 KCNJ10 KCNJ12 KCNJ15 KCNJ16 MAOA MDM2 ACHE MYO6 NEFL NSF PDPK1 GNG13 PLCB2 PLCB3 GNG2 SLC38A2 CHRNA9 PRKACB PRKCA PRKCB CACNA2D3 PRKCG MAPK1 GNG12 SLC17A7 RAB3A RAF1 RASGRF1 RASGRF2 CACNG8 GNB4 SLC5A7 RPS6KA1 RPS6KA2 RPS6KA3 RRAS SLC1A1 SLC1A2 SLC1A3 SLC1A6 SLC1A7 LOC651907 SLC6A1 SLC6A3 SLC6A11 SLC6A12 SLC18A2 SLC18A3 SLC22A2 SNAP25 BRAF STX1A STXBP1 VAMP2 SYN1 SYN2 SYT1 LOC732445 CACNA1A CACNA1B CACNB1 CACNB2 CACNB3 CACNB4 ALDH5A1 CALM1 DNAJC5 CALM2 CALM3 GRIP2 CAMK4 CAMK2A SLC38A1 CAMK2B CAMK2D SYN3 NCALD CAMKK1 ACTN2 CHRNA6 CHRFAM7A GNG8 PICK1 AKAP5 GABBR2 +REACTOME_P75NTR_SIGNALS_VIA_NFKB http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_P75NTR_SIGNALS_VIA_NFKB IKBKB IRAK1 MYD88 NFKBIA NGF NGFR PRKCI RELA RPS27A TRAF6 RPS27AP11 UBA52 RIPK2 SQSTM1 +REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS ADD1 GAS2 DBNL GSN MAPT PLEC LOC652460 SPTAN1 VIM CASP3 CASP6 CASP7 CASP8 +REACTOME_XENOBIOTICS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_XENOBIOTICS CYP1A1 CYP1A2 CYP2A6 CYP3A7 CYP2A13 CYP2B6 CYP2C19 CYP2C8 CYP2C9 CYP2C18 CYP2D6 CYP2E1 CYP2F1 CYP3A4 CYP3A5 LOC731992 +REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS RASGRP1 RASGRP2 RAPGEF3 RAPGEF4 AMICA1 COL1A1 COL1A2 COL2A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 CRK CSK AKT1 FBN1 FGA FGB FGG ITGA11 FN1 LAMA1 GRB2 TNC IBSP ICAM1 ICAM2 ICAM3 ICAM4 ITGA1 ITGA2 ITGA2B ITGA3 ITGA5 ITGA9 ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 LAMA2 LAMA5 LAMB1 LAMB2 LAMC1 F11R PDPK1 PECAM1 APBB1IP PTK2 PTPN1 JAM2 RAP1A RAP1B SHC1 SOS1 SPP1 SRC BSG SYK THBS1 TLN1 VCAM1 VTN VWF JAM3 ITGA10 ITGA8 BCAR1 CDH1 +REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC PSMD14 PSMA8 NQO1 PSME4 OAZ1 OAZ2 ODC1 AZIN1 OAZ3 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 LOC652826 PSMF1 PSMD6 +REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE CYP46A1 CYP4F8 CYP2U1 CYP2R1 CYP1A1 CYP1A2 CYP1B1 CYP2A6 CYP3A7 CYP2A13 CYP2B6 CYP2C19 CYP2C8 CYP2C9 CYP2C18 CYP2D6 CYP2E1 CYP2F1 CYP2J2 CYP3A4 CYP3A5 CYP4A11 CYP4B1 CYP7A1 CYP8B1 CYP11A1 CYP11B1 CYP11B2 CYP17A1 CYP19A1 CYP21A2 CYP24A1 CYP26A1 CYP27A1 CYP27B1 CYP51A1 CYP2S1 CYP26C1 CYP4F3 CYP39A1 POMC CYP2W1 CYP26B1 PTGIS CYP4F11 CYP3A43 CYP4F12 TBXAS1 LOC731992 CYP4F2 CYP7B1 +REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY CCNO SMUG1 APEX1 MPG MUTYH NTHL1 OGG1 POLB TDG MBD4 +REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS CTNNB1 DSG1 DSG2 DSG3 DSP OCLN PKP1 LOC647859 TJP1 CASP3 TJP2 CDH1 +REACTOME_HDL_MEDIATED_LIPID_TRANSPORT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HDL_MEDIATED_LIPID_TRANSPORT CETP ABCA1 A2M ALB APOA1 APOC2 APOC3 APOE LCAT PLTP BMP1 CUBN AMN SCARB1 ABCG1 +REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK BCL2L11 NET1 VAV3 AKAP13 FGD4 ECT2 FGD2 FGD1 ARHGEF9 ARHGEF12 ARHGEF18 NGEF TIAM2 AATF ARHGEF16 ABR ARHGAP4 MCF2 NGF NGFR ARHGEF4 ARHGEF3 MAPK8 BAD PREX1 RAC1 RASGRF1 RASGRF2 ITSN1 PLEKHG2 SOS1 SOS2 TIAM1 TRIO VAV1 OBSCN FGD3 KALRN ARHGEF2 ARHGEF6 MAGED1 ARHGEF11 ARHGEF17 +REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS LSM11 NCBP2 ZNF473 NCBP1 SNRPB SNRPD3 SNRPE SNRPF SNRPG SLBP LSM10 +REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS NCSTN ITGB3BP NGF NGFR APH1A PSENEN MAPK8 PSEN1 PSEN2 RPS27A TRAF6 RPS27AP11 UBA52 APH1B SQSTM1 +REACTOME_REGULATION_OF_APOPTOSIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_APOPTOSIS PSMD14 PSMA8 DAPK1 DAPK3 DCC UNC5B PSME4 DAPK2 APPL1 PAK2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RPS27A LOC652826 RPS27AP11 UBA52 ARHGAP10 CASP3 CASP9 UNC5A PSMF1 MAGED1 PSMD6 +REACTOME_RNA_POL_II_TRANSCRIPTION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_II_TRANSCRIPTION THOC4 CDK7 CDK9 SRRM1 PAPOLA RNPS1 CLP1 NUDT21 SUPT16H U2AF2 LSM11 CSTF1 CSTF2 CSTF3 ERCC2 ERCC3 NCBP2 ZNF473 COBRA1 GTF2A1 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 CPSF1 MAGOH MNAT1 NCBP1 NFX1 CDC40 TH1L PCF11 CPSF3 CPSF2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L SRSF1 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 LOC643446 TCEB1P3 UPF3B LOC652857 GTF2H2B SNRPB SNRPD3 SNRPE SNRPF SNRPG SSRP1 SUPT4H1 SUPT5H TAF1 TAF4 TAF4B TAF5 TAF6 TAF9 TAF10 TAF11 TAF12 TAF13 TBP TCEA1 TCEB1 TCEB2 TCEB3 U2AF1 WHSC2 SLBP RDBP CPSF7 PABPN1 ELL LSM10 SRSF9 RNMT RNGTT CCNH CCNT1 CCNT2 CTDP1 SRSF11 DHX38 RBM8A +REACTOME_NEURONAL_SYSTEM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEURONAL_SYSTEM HCN4 GJC1 ABCC9 KCNK7 AKAP9 STX6 KCNMB2 CACNG3 CACNG2 UNC13B GNB5 ADCY1 ADCY2 ADCY3 CHAT ADCY5 ADCY6 STX1B ADCY7 CHRNA1 CHRNA2 CHRNA3 CHRNA4 CHRNA5 CHRNA7 ADCY8 CHRNB2 CHRNB3 CHRNB4 CHRND CHRNE CHRNG ADCY9 AP2M1 AP2S1 SYT2 KCNH8 COMT CREB1 SLC32A1 AP2A1 AP2A2 AP2B1 KCNV2 KCNG3 DLG1 DLG3 ABAT ADCY4 EPB41L1 STX2 ALDH2 RIMS1 ARHGEF9 PLCB1 KCNH4 KCNH3 STX12 PANX1 GABBR1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRG2 GABRG3 GABRR1 GABRR2 GAD1 GAD2 KCNG2 KCNV1 CACNG4 KCNMB3 KCNH5 GLS2 RPS6KA6 KCNMB4 GLS GLUL GNAI1 GNAI2 GNAI3 GNAL GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GRIA1 GRIA2 GRIA3 GRIA4 GRIK1 GRIK2 GRIK3 GRIK4 GRIK5 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D HRAS HSPA8 KCNK18 HCN1 KCNA1 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNA10 KCNB1 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNG1 KCNH1 KCNH2 KCNJ1 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6 KCNJ8 KCNJ9 KCNJ10 KCNJ11 KCNJ12 KCNJ14 KCNJ15 KCNJ16 KCNK1 KCNK2 KCNK3 KCNMB1 KCNN1 KCNN2 KCNN3 KCNN4 KCNQ1 KCNQ2 KCNQ3 KCNS1 KCNS2 KCNS3 MAOA MDM2 ACHE MYO6 NEFL NSF KCNK4 KCNK9 PDPK1 GNG13 PLCB2 PLCB3 KCNK10 GNG2 SLC38A2 CHRNA9 PRKACB PRKCA PRKCB CACNA2D3 PRKCG MAPK1 GNG12 KCNQ5 KCNK13 PANX2 SLC17A7 GJD2 HCN3 RAB3A RAF1 RASGRF1 RASGRF2 CACNG8 GNB4 SLC5A7 HCN2 RPS6KA1 RPS6KA2 RPS6KA3 RRAS LOC642105 SLC1A1 SLC1A2 SLC1A3 SLC1A6 SLC1A7 LOC651907 SLC6A1 SLC6A3 SLC6A11 SLC6A12 SLC18A2 SLC18A3 SLC22A2 SNAP25 BRAF STX1A STX3 STX4 STX5 STXBP1 ABCC8 VAMP1 VAMP2 SYN1 SYN2 SYT1 LOC732445 CACNA1A CACNA1B CACNB1 CACNB2 CACNB3 CACNB4 KCNAB1 ALDH5A1 CALM1 DNAJC5 CALM2 CALM3 GRIP2 KCNH6 CAMK4 CAMK2A SLC38A1 CAMK2B CAMK2D SYN3 KCNK16 NCALD STX7 CAMKK1 GJA10 KCNAB2 STX16 STX11 STX10 ACTN2 CHRNA6 KCNK17 CHRFAM7A KCNH7 KCNQ4 KCNAB3 KCNG4 KCNB2 GNG8 KCNK6 PICK1 STX8 AKAP5 GABBR2 +REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL IKBKB IRAK1 NFKBIA NGF NGFR RELA RPS27A TRAF6 RPS27AP11 UBA52 SQSTM1 +REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT AKT3 AKT1 AKT2 FGF10 FOXO1 NR5A2 PTF1A GCK FOXA2 FOXA3 HNF4A HNF4G ONECUT1 HES1 IAPP RBPJ INS INSM1 PDX1 MAFA ONECUT3 NEUROD1 NKX2-2 NKX6-1 NEUROG3 PAX6 PKLR SLC2A2 HNF1A HNF1B +REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS CYP46A1 CYP4F8 CYP2U1 CYP2R1 ADH1A ADH1B ADH1C ADH4 ADH6 ADH7 CYP1A1 CYP1A2 CYP1B1 CYP2A6 CYP3A7 CYP2A13 CYP2B6 CYP2C19 CYP2C8 CYP2C9 CYP2C18 CYP2D6 CYP2E1 CYP2F1 CYP2J2 CYP3A4 CYP3A5 CYP4A11 CYP4B1 CYP7A1 CYP8B1 CYP11A1 CYP11B1 CYP11B2 CYP17A1 CYP19A1 CYP21A2 CYP24A1 CYP26A1 CYP27A1 CYP27B1 CYP51A1 PAOX ALDH1A1 ALDH2 FMO1 FMO2 FMO3 CYP2S1 CYP26C1 CYP4F3 MAOA MAOB CYP39A1 POMC SMOX CYP2W1 ACSS2 CYP26B1 PTGIS PTGS1 PTGS2 CYP4F11 CYP3A43 CYP4F12 TBXAS1 LOC731992 ACSS1 CYP4F2 CYP7B1 +REACTOME_RNA_POL_III_TRANSCRIPTION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_III_TRANSCRIPTION SNAPC5 POLR3F POLR3C POLR3A LZTS1 POLR3H BRF1 GTF3C2 NFIB POLR1D POLR3K POLR2E POLR2F POLR2H POLR2K POLR2L POU2F1 BRF2 POLR3B POLR3E POLR3D SNAPC1 SNAPC2 SNAPC3 SNAPC4 SSB TBP ZNF143 POLR3GL GTF3C5 GTF3C4 GTF3C3 POLR1C +REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE BCL2L11 NET1 VAV3 AKAP13 FGD4 ECT2 FGD2 FGD1 ARHGEF9 ARHGEF12 ARHGEF18 NCSTN ITGB3BP NGEF TIAM2 AATF NGFRAP1 ARHGEF16 ABR ARHGAP4 MCF2 LOC440917 NGF NGFR ARHGEF4 ARHGEF3 APH1A PSENEN MAPK8 PSEN1 PSEN2 BAD PREX1 RAC1 RASGRF1 RASGRF2 RPS27A ITSN1 PLEKHG2 SOS1 SOS2 TIAM1 TRAF6 TRIO RPS27AP11 UBA52 VAV1 YWHAE APH1B CASP2 CASP3 OBSCN SQSTM1 FGD3 KALRN ARHGEF2 ARHGEF6 MAGED1 ARHGEF11 ARHGEF17 +REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE UNC13B CHAT SLC32A1 ABAT RIMS1 GAD1 GAD2 GLS2 GLS HSPA8 MAOA SLC38A2 SLC17A7 RAB3A SLC5A7 SLC1A1 SLC1A6 SLC1A7 SLC6A1 SLC6A11 SLC6A12 SLC18A2 SLC18A3 SLC22A2 SNAP25 STX1A STXBP1 VAMP2 SYN1 SYN2 SYT1 ALDH5A1 DNAJC5 SYN3 +REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING BCL2L11 NET1 VAV3 PRDM4 AKAP13 FGD4 ECT2 FGD2 FGD1 SORCS3 ARHGEF9 ARHGEF12 ARHGEF18 NCSTN ITGB3BP NGEF TIAM2 AATF NGFRAP1 ARHGEF16 ABR HDAC1 HDAC2 IKBKB IRAK1 RHOA ARHGAP4 ARHGDIA MAG MCF2 LOC440917 MYD88 NFKBIA NGF NGFR OMG ARHGEF4 ARHGEF3 APH1A PRKCI PSENEN MAPK8 PSEN1 PSEN2 RTN4 BAD PREX1 RAC1 RASGRF1 RASGRF2 RELA RPS27A ITSN1 PLEKHG2 SMPD2 SOS1 SOS2 ADAM17 TIAM1 TRAF6 TRIO RPS27AP11 UBA52 VAV1 YWHAE APH1B CASP2 CASP3 OBSCN LINGO1 RIPK2 HDAC3 SQSTM1 FGD3 KALRN ARHGEF1 ARHGEF2 ARHGEF6 MAGED1 ARHGEF11 ARHGEF17 +REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE SLC38A3 SLC7A9 SLC6A14 SLC16A10 SLC43A2 SLC36A2 SLC36A1 SLC7A8 SLC7A11 SLC6A19 SLC6A18 SLC38A2 SLC6A20 SLC38A4 SLC6A15 SLC7A10 SLC1A4 SLC1A5 SLC3A1 SLC3A2 SLC6A6 SLC6A12 SLC7A1 SLC7A2 SLC7A5 SLC38A1 SLC7A3 SLC43A1 SLC7A7 SLC7A6 SLC38A5 +REACTOME_ENDOGENOUS_STEROLS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ENDOGENOUS_STEROLS CYP46A1 CYP1B1 CYP7A1 CYP8B1 CYP11A1 CYP11B1 CYP11B2 CYP17A1 CYP19A1 CYP21A2 CYP27A1 CYP51A1 CYP39A1 POMC CYP7B1 +REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS AKT3 AKT1 AKT2 FOXO1 GCK FOXA2 FOXA3 HNF4A HNF4G IAPP INS PDX1 MAFA NEUROD1 NKX2-2 NKX6-1 PAX6 PKLR SLC2A2 HNF1A +REACTOME_GLYCOLYSIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLYCOLYSIS ENO1 ENO2 ENO3 ALDOA ALDOB ALDOC GAPDH GAPDHS GPI PFKFB1 PFKFB2 PFKFB3 PFKFB4 PFKL PFKM PFKP PGAM1 PGAM2 PGK1 PKLR PKM2 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D LOC642969 TPI1 TPI1P1 +REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND POLD3 DNA2 FEN1 POLA2 LIG1 PCNA POLA1 POLD1 POLD2 PRIM1 PRIM2 POLD4 RPA1 RPA2 RPA3 +REACTOME_PEPTIDE_CHAIN_ELONGATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PEPTIDE_CHAIN_ELONGATION RPL35 RPL7AP27 EEF1A1 EEF2 FAU RPL13A RPL36 RPL10P16 FAM153A RPL36P14 RPSAP12 RPS8P10 RPL7AP66 RPL10P9 RPS12P4 RPSA RPS26P10 RPL23AP2 RPS12P22 RPL21P29 RPS26P35 RPL10A RPL26L1 RPL3 RPL3L RPL4 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL10 RPL11 RPL12 RPL13 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL23A RPL24 RPL26 RPL27 RPL30 RPL27A RPL28 RPL29 RPL31 RPL32 RPL34 RPL35A RPL37 RPL37A RPL38 RPL39 RPL41 RPL36A RPLP0 RPLP1 RPLP2 RPS2 RPS3 RPS3A RPS4X RPS4Y1 RPS5 RPS6 RPS7 RPS8 RPS9 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS18 RPS19 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS28 RPS29 RPL6P19 LOC641895 RPL36AP31 RPS29P3 RPS26P28 RPL36AP8 RPL26P22 RPS26P20 RPS15AP11 RPS26P50 RPL22P11 RPL17P6 RPS13P8 RPS28P4 RPL32P16 LOC646184 RPS28P7 RPL12P2 LOC647074 RPL23AP42 RPL5P1 RPL36AP51 LOC649602 RPS28P9 RPL34P27 LOC651825 LOC651894 RPL26P30 RPSAP9 RPL19P9 RPL21P119 RPL31P17 LOC653881 RPL31P31 RPL15P17 RPL23AP18 RPL26P24 RPL21P75 RPS27AP11 RPS26P7 RPL21P134 RPS26P25 RPS19P3 RPL36AP23 RPS18P10 RPL17P36 RPL36AP37 RPL21P16 RPL23AP74 RPS15P5 RPL23AP63 RPS10P9 LOC730343 RPS18P5 UBA52 RPL34P31 RPL14 RPL23 +REACTOME_COMMON_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_COMMON_PATHWAY F2 F5 F10 F13A1 F13B FGA FGB FGG SERPINC1 PF4 PF4V1 PROC PROS1 THBD +REACTOME_MRNA_CAPPING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MRNA_CAPPING CDK7 ERCC2 ERCC3 NCBP2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 MNAT1 NCBP1 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L LOC652857 GTF2H2B SUPT5H RNMT RNGTT CCNH +REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION ECI1 DECR1 ECHS1 HADHA HADHB HADH ACADL ACADM ACADS ACADVL MUT PCCA PCCB MCEE +REACTOME_SIGNALING_BY_GPCR http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_GPCR AKT3 INSL5 RASGRP1 LPAR6 CDK5 CALCRL RASGRP2 RAMP2 RAMP1 RAMP3 NET1 RGS19 NMUR1 VAV3 CXCL13 CXCR6 GNA13 GNB5 RRH ADCY1 OR5I1 ADCY2 CYSLTR1 CCR9 CGA PDE10A CCL27 NMU NPFFR2 PROKR1 ADCY3 UTS2 ADCY5 ADCY6 FZD10 AKAP13 GPR44 HRH3 CHRM1 CHRM2 ADCY7 PTH2 CHRM3 CHRM5 MGLL ADCY8 ADCY9 ARHGEF25 ADCYAP1 ADCYAP1R1 RLN3 OR52E2 OR52J3 OR51L1 OR51A7 OR51S1 OR51F2 OR52R1 OR4X2 OR4B1 OR52M1 OR52K2 OR5P2 OR5P3 OR8I2 OR2D3 OR2D2 OR52W1 OR56A4 OR56A1 OR10P1 OR10AD1 OR10A7 FGD4 RXFP2 OR4K14 OR4L1 CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCBP2 LTB4R OR4D2 OR7D4 OR7G1 OR1M1 OR1I1 OR10H4 CNR1 CNR2 OR2M5 OR2M3 OR2T12 OR14C36 OR2T34 OR2T10 OR2T4 OR2T11 OR10J5 OR2B11 OR10T2 OR10X1 OR10Z1 OR6K6 OR6N1 PROKR2 NMS OR9A4 ADM ADORA1 OR2Y1 TAAR1 ADORA2A OR9A2 OR2A14 OR6B1 OR2F2 ADORA2B CREB1 OR1L8 OR1N2 OR1N1 DGKK CRH CRHR2 ADORA3 OR52B4 OR52I2 OR51E1 OR10A5 OR2AG1 ADRA1D PIK3R6 ADRA1B ADRA1A ADRA2A OR6B3 ADRA2B GPBAR1 CX3CR1 ADRB1 ADRB2 ADRB3 ADRBK1 OR1Q1 CD55 DGKA DGKB DGKG DGKH DGKQ OR7D2 OXER1 DRD1 DRD2 DRD3 DRD5 AGT HBEGF AGTR1 AGTR2 APLNR ECT2 S1PR1 LPAR1 S1PR3 EDN1 EDN2 EDN3 EDNRA EDNRB EGFR OR56B4 ADCY4 EMR1 AKT1 AKT2 F2 F2R F2RL1 F2RL2 OR8U1 OR4C16 OR4C11 OR4S2 OR4C6 OR5D14 OR5L1 OR5D18 OR5AS1 OR8K5 OR5T2 OR8H1 OR8K3 OR8J1 OR5R1 OR5M3 OR5M8 OR5AR1 OR8B12 OR10G8 OR10G9 OR10S1 OR6T1 OR4D5 OR6Q1 OR9I1 OR9Q1 OR9Q2 OR1S2 OR1S1 OR10Q1 OR5B17 OR5A2 OR5A1 OR4D6 OR4D11 OPN5 FGD2 DAGLB GPRC6A FGD1 ARHGEF9 PLCB1 ARHGEF12 ARHGEF18 PIK3R5 OR52A1 LPAR3 FPR1 FPR2 FPR3 OPN3 NTSR2 FSHB FSHR GAST DARC FZD2 OR6C3 OR1L4 GABBR1 OR4C3 OR4S1 NPB UTS2D NGEF GALR1 OR1C1 OR1A2 OR2F1 OR2B6 OR1J4 TIAM2 OR2M4 OR2L2 OR2K2 OR7A17 OR5L2 OR5K1 GCG GCGR OR10J1 OR8B8 OR10A3 OPN1MW OR11A1 OR10H3 OR10G3 OR10G2 OR10H2 OR10H1 RGS17 OR7C2 OR7A5 OR7C1 OR4F4 OR4F3 OR4E2 OR4D1 OR2W1 OR2T1 OR2H1 OR1L3 OR1L1 OR1J2 GHRH GHRHR GHSR GIP GIPR PDE7B GPR77 ARHGEF16 P2RY10 GLP1R GNA11 GNA12 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAQ GNAS GNAT1 GNAT2 GNAZ GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GNRH1 GNRH2 GNRHR CCR10 OR51B5 OR10AG1 OR5J2 GPR4 XCR1 OR4C13 OR4C12 NPBWR1 OR51V1 OR8D1 OR8D2 OR8B4 OR9G4 NPBWR2 OR10A4 CXCR3 PRLHR OR4N4 UTS2R NPW GPR17 GPR18 OR2Z1 OR10H5 OR2L13 OR14A16 LPAR4 MCHR1 GPER OR2V2 MLNR GPR39 FFAR1 FFAR3 FFAR2 GRK5 GRB2 ABR GRM1 GRM2 GRM3 GRM4 GRM6 GRM7 GRM8 CXCL1 CXCL2 CXCL3 GRP GRPR GPR132 ANXA1 HCRT HCRTR1 HCRTR2 EMR2 TAAR6 HRAS HRH1 HRH2 HTR1A HTR1B HTR1D HTR1E HTR1F HTR2A HTR2B HTR2C HTR4 HTR5A HTR6 HTR7 IAPP HCAR2 O3FAR1 OR8D4 OR5F1 OR5AP2 OR52L1 RXFP4 OR52B6 OR10A2 OR6C2 OR6C4 OR8S1 OR6S1 OR6F1 OR14K1 OR2W3 OR2T3 OR10R2 OR2T29 OR6V1 OR2A12 OR2A1 QRFP OR1J1 OR1B1 APP IHH IL8 CXCR1 CXCR2 CXCL10 INSL3 ITPR2 ITPR3 KISS1 KNG1 KRAS RHOA NPSR1 OR56B1 RHOB RHOC OR6B2 OR52K1 OR52I1 OR51D1 OR52A5 OR51B6 OR51M1 OR51Q1 OR51I1 OR51I2 OR52D1 OR52H1 OR52N4 OR52N5 OR52N2 OR52E6 OR52E8 OR52E4 OR56A3 OR10A6 OR4X1 OR5D13 OR5D16 OR5W2 OR8H2 OR8H3 OR5T3 OR5T1 OR8K1 OR5M9 OR9G1 OR5AK2 OR5B2 OR5B12 OR5AN1 OR4D9 OR10V1 OR6X1 OR6M1 OR10G4 OR10G7 OR8B3 OR8A1 OR6C1 OR4N2 OR4K2 OR4K13 OR4K17 OR4N5 OR11G2 OR5AU1 OR4M2 OR4F6 OR4F15 OR3A4P OR7G2 OR7G3 OR7A10 RHOG OR10K2 OR10K1 OR6Y1 OR6K3 OR2L8 OR2AK2 OR2L3 OR2M2 OR2T33 OR2M7 OR2G6 OR2A25 OR1L6 OR5C1 OR1K1 ARHGAP4 OR2A5 LHB LHCGR OR2A7 OR51T1 OR51A4 OR51A2 OR2T2 OR2T5 OR5K2 OR2A42 OR2T27 OR2T35 OR4A47 CCL3L3 MC1R MC2R MC3R MC4R MC5R MCF2 CXCL9 MLN MMP3 RGS21 OR5B3 OR9K2 OR4Q3 OR4M1 OR10J3 OR2B3 OR2J3 OR14J1 OR10C1 OR2A2 MTNR1A MTNR1B NMB NMBR NPY NPY1R NPY2R NPY5R NRAS NTS NTSR1 OPRD1 OPRK1 OPRL1 OPRM1 OR1D2 OR1F1 OR2C1 OR3A1 OR3A2 OXT OXTR P2RY1 P2RY2 P2RY4 P2RY6 P2RY11 OR8U8 OR8U9 OR9G9 ARHGEF4 ARHGEF3 DHH HEBP1 PDE11A PRLH GAL RXFP3 PDE1A PDE2A WNT16 PDE3A PDE3B PDE4B PDE4C PDE4D PDE7A PDE8A PDE1B CCRL1 PDPK1 PDYN GHRL GNG13 PENK PF4 PIK3CA PIK3CG PIK3R1 PIK3R2 PLA2G4A PLCB2 PLCB3 PLCB4 S1PR5 PLXNB1 PMCH PNOC P2RY13 GNG2 WNT4 POMC PPBP PPP1CA AVP PPP2CA PPP2CB PPP2R1A PPP2R1B AVPR1A PPP2R5D AVPR1B PPP3CA PPP3CB PPP3R1 PPY AVPR2 PPYR1 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCQ MAPK1 MAPK3 GNG12 MAPK7 MAP2K1 MAP2K2 LTB4R2 CCL28 OR2S2 NMUR2 PYY CXCR7 CYSLTR2 TRPC7 PTAFR PTCH1 PTGDR PTGER1 PTGER2 PTGER3 PTGER4 PTGFR PTGIR PTH PTHLH PTH1R PTH2R PREX1 CXCL16 RAC1 RAC2 RAF1 RASGRF1 RASGRF2 HRH4 GNB4 RXFP1 NPS OPN1LW RGR RGS1 RGS2 RGS4 RGS7 RGS12 RHO RLN2 ROCK1 OPN1SW RPS6KA1 RPS6KA2 RPS6KA3 BDKRB1 BDKRB2 SAA1 SCT SCTR CCL2 CCL3 CCL3L1 CCL4 CCL5 CCL7 CCL11 CCL16 CCL17 CCL19 CCL20 CCL21 CCL22 CCL25 CXCL6 CXCL11 CXCL5 XCL1 CX3CL1 CXCL12 NPFFR1 CXCR5 RGS18 ITSN1 SHH P2RY12 PLEKHG2 LOC649279 OR4N3P CCRL1P1 LOC652222 LOC652292 LOC652692 LOC653879 SMO SOS1 SOS2 SST SSTR1 SSTR2 SSTR3 SSTR4 SSTR5 BRS3 XCL2 TAC1 TACR2 TAC3 TACR1 TACR3 TBXA2R TIAM1 C3 C3AR1 TRH TRHR TRIO TRPC3 TRPC6 TSHB TSHR C5 ROCK1P1 C5AR1 OPN1MW2 LOC728830 OR4F29 LOC730002 LOC730221 LOC730335 LOC730413 LOC730418 LOC730421 LOC730808 LOC731823 VAV1 VIP VIPR1 VIPR2 DAGLA WNT1 WNT2 WNT3 WNT5A WNT6 WNT7A WNT7B WNT8B WNT10B WNT11 WNT2B WNT9A WNT9B YWHAB CXCR4 FZD5 OR5H6 OR5H2 OR4K5 OR51G1 OR51B4 OR51B2 OR52N1 OR4F5 OR2A4 OR4K1 CALCA CALCB FZD3 ADM2 CALM1 WNT10A CALM2 CALM3 TAS1R2 TAS1R1 OR5AC2 OR4F17 GPR68 OR4K15 OR8J3 OR51G2 OR51E2 OR4P4 OR4C15 OR4A5 OR4A16 OR4A15 OR10W1 OR2AE1 OR4F16 CAMK4 OR6N2 OR6K2 OR2G3 OR2G2 OR2C3 OR5V1 OR2B2 FZD1 FZD4 FZD6 FZD7 FZD8 FZD9 TAAR8 TAS1R3 OR1A1 OR1D4 OR1D5 OR1E1 OR1E2 OR1G1 OR3A3 OBSCN QRFPR PPP1R1B PROK1 MCHR2 CASR KISS1R EMR3 GPR65 GALR3 PIK3R3 DGKE DGKD RGS8 OR6A2 RGS20 NPFF PDE8B PTCH2 S1PR4 RGS11 RGS9 GALR2 HCAR3 CCK CCKAR CCKBR WNT3A FGD3 KALRN F2RL3 TAAR5 ARHGEF1 DGKI LPAR2 ARHGEF2 TAAR2 GPR55 S1PR2 GLP2R OPN4 GNG8 ARHGEF6 ROCK2 GABBR2 RGS6 GNA14 CD97 ARHGEF11 ARHGEF17 CDK1 P2RY14 CDC42 +REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS INSL5 NMUR1 CXCL13 CXCR6 CCR9 CCL27 NMU NPFFR2 PROKR1 UTS2 RLN3 RXFP2 CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCBP2 PROKR2 NMS CX3CR1 AGT AGTR1 AGTR2 APLNR EDN1 EDN2 EDN3 EDNRA EDNRB F2 F2R F2RL1 F2RL2 FPR1 FPR2 FPR3 NTSR2 GAST DARC NPB UTS2D GALR1 GHSR GPR77 CCR10 XCR1 NPBWR1 NPBWR2 CXCR3 PRLHR UTS2R NPW MCHR1 GPER MLNR CXCL1 CXCL2 CXCL3 GRP GRPR ANXA1 HCRT HCRTR1 HCRTR2 RXFP4 QRFP APP IL8 CXCR1 CXCR2 CXCL10 INSL3 KISS1 KNG1 NPSR1 CCL3L3 MC1R MC2R MC3R MC4R MC5R CXCL9 MLN NMB NMBR NPY NPY1R NPY2R NPY5R NTS NTSR1 OPRD1 OPRK1 OPRL1 OPRM1 OXT OXTR HEBP1 PRLH GAL RXFP3 CCRL1 PDYN GHRL PENK PF4 PMCH PNOC POMC PPBP AVP AVPR1A AVPR1B PPY AVPR2 PPYR1 CCL28 NMUR2 PYY CXCR7 CXCL16 RXFP1 NPS RLN2 BDKRB1 BDKRB2 SAA1 CCL2 CCL3 CCL3L1 CCL4 CCL5 CCL7 CCL11 CCL16 CCL17 CCL19 CCL20 CCL21 CCL22 CCL25 CXCL6 CXCL11 CXCL5 XCL1 CX3CL1 CXCL12 NPFFR1 CXCR5 CCRL1P1 LOC652222 LOC653879 SST SSTR1 SSTR2 SSTR3 SSTR4 SSTR5 BRS3 XCL2 TAC1 TACR2 TAC3 TACR1 TACR3 C3 C3AR1 TRH TRHR C5 C5AR1 LOC728830 CXCR4 QRFPR PROK1 MCHR2 KISS1R GALR3 NPFF GALR2 CCK CCKAR CCKBR F2RL3 +REACTOME_METABOLISM_OF_POLYAMINES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_POLYAMINES ADC PAOX AMD1 GOT1 MTAP ODC1 APIP SMOX ADI1 ENOPH1 SAT1 SMS SRM AGMAT MRI1 +REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS INSL5 LPAR6 NMUR1 CXCL13 CXCR6 RRH CYSLTR1 CCR9 CGA CCL27 NMU NPFFR2 PROKR1 UTS2 GPR44 HRH3 CHRM1 CHRM2 CHRM3 CHRM5 RLN3 RXFP2 CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCBP2 LTB4R CNR1 CNR2 PROKR2 NMS ADORA1 TAAR1 ADORA2A ADORA2B ADORA3 ADRA1D ADRA1B ADRA1A ADRA2A ADRA2B GPBAR1 CX3CR1 ADRB1 ADRB2 ADRB3 OXER1 DRD1 DRD2 DRD3 DRD5 AGT AGTR1 AGTR2 APLNR S1PR1 LPAR1 S1PR3 EDN1 EDN2 EDN3 EDNRA EDNRB F2 F2R F2RL1 F2RL2 OPN5 LPAR3 FPR1 FPR2 FPR3 OPN3 NTSR2 FSHB FSHR GAST DARC NPB UTS2D GALR1 OPN1MW GHSR GPR77 P2RY10 GNRH1 GNRH2 GNRHR CCR10 GPR4 XCR1 NPBWR1 NPBWR2 CXCR3 PRLHR UTS2R NPW GPR17 GPR18 LPAR4 MCHR1 GPER MLNR GPR39 FFAR1 FFAR3 FFAR2 CXCL1 CXCL2 CXCL3 GRP GRPR GPR132 ANXA1 HCRT HCRTR1 HCRTR2 TAAR6 HRH1 HRH2 HTR1A HTR1B HTR1D HTR1E HTR1F HTR2A HTR2B HTR2C HTR4 HTR5A HTR6 HTR7 HCAR2 O3FAR1 RXFP4 QRFP APP IL8 CXCR1 CXCR2 CXCL10 INSL3 KISS1 KNG1 NPSR1 LHB LHCGR CCL3L3 MC1R MC2R MC3R MC4R MC5R CXCL9 MLN MTNR1A MTNR1B NMB NMBR NPY NPY1R NPY2R NPY5R NTS NTSR1 OPRD1 OPRK1 OPRL1 OPRM1 OXT OXTR P2RY1 P2RY2 P2RY4 P2RY6 P2RY11 HEBP1 PRLH GAL RXFP3 CCRL1 PDYN GHRL PENK PF4 S1PR5 PMCH PNOC P2RY13 POMC PPBP AVP AVPR1A AVPR1B PPY AVPR2 PPYR1 LTB4R2 CCL28 NMUR2 PYY CXCR7 CYSLTR2 PTAFR PTGDR PTGER1 PTGER2 PTGER3 PTGER4 PTGFR PTGIR CXCL16 HRH4 RXFP1 NPS OPN1LW RGR RHO RLN2 OPN1SW BDKRB1 BDKRB2 SAA1 CCL2 CCL3 CCL3L1 CCL4 CCL5 CCL7 CCL11 CCL16 CCL17 CCL19 CCL20 CCL21 CCL22 CCL25 CXCL6 CXCL11 CXCL5 XCL1 CX3CL1 CXCL12 NPFFR1 CXCR5 P2RY12 CCRL1P1 LOC652222 LOC653879 SST SSTR1 SSTR2 SSTR3 SSTR4 SSTR5 BRS3 XCL2 TAC1 TACR2 TAC3 TACR1 TACR3 TBXA2R C3 C3AR1 TRH TRHR TSHB TSHR C5 C5AR1 OPN1MW2 LOC728830 LOC730002 LOC730413 LOC731823 CXCR4 GPR68 TAAR8 QRFPR PROK1 MCHR2 KISS1R GPR65 GALR3 NPFF S1PR4 GALR2 HCAR3 CCK CCKAR CCKBR F2RL3 TAAR5 LPAR2 TAAR2 GPR55 S1PR2 OPN4 P2RY14 +REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY MAMLD1 CREBBP SNW1 KAT2A RBPJ NOTCH2 NOTCH3 NOTCH4 MAML3 LOC728030 MAML2 KAT2B MAML1 +REACTOME_INTEGRATION_OF_ENERGY_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTEGRATION_OF_ENERGY_METABOLISM RAPGEF3 CDX2 AGPAT1 GNB5 ADCY1 ADCY2 ADCY3 RAPGEF4 ADCY5 ADCY6 ADCY7 CHRM3 ADCY8 ADCY9 GPR119 CTNNB1 ADRA2A DPP4 ADCY4 FASN PLCB1 SEC11A KCNG2 GATA4 GCG GCGR GIP GLP1R GNA11 GNA15 GNAI1 GNAI2 GNAO1 GNAQ GNAS GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 FFAR1 SPCS1 SLC25A4 SLC25A5 GRP SLC25A6 ACACA ACACB O3FAR1 INS ISL1 ITPR2 ITPR3 KCNB1 KCNC2 KCNJ11 KCNS3 LEP MARCKS ACLY PAX6 MLXIPL PCSK1 PRKAG2 GNG13 PFKFB1 PKLR PLCB2 PLCB3 GNG2 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D PRKAA2 PRKAB2 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA GNG12 RAP1A RAP1B GNB4 SPCS3 SLC2A1 SLC2A2 LOC653566 SNAP25 STK11 STX1A STXBP1 ABCC8 VAMP2 SYT5 TALDO1 MLX TKT LOC730413 LOC730418 CACNA1A CACNB2 CACNB3 IQGAP1 SEC11C GNG8 AKAP5 GNA14 SPCS2 +REACTOME_CELL_CYCLE_MITOTIC http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_CYCLE_MITOTIC KIF20A ACTR1A AKAP9 CDK2 CDK4 CDK6 PSMD14 CDK7 CDKN1A CDKN1B STAG1 CDKN2A CDKN2B CDKN2C CDKN2D TUBB4A TUBB4B ANAPC10 NDC80 TUBGCP3 DCTN2 CENPA CENPC1 CETN2 POLD3 NUDC PLK4 STAG2 SDCCAG8 TUBGCP2 DBF4 KIF2C CNTRL UBE2C FGFR1OP ZWINT CEP250 PMF1 DCTN3 TUBGCP5 CKS1B NEDD1 LIN54 PSMA8 CSNK1D CSNK1E SPC24 SGOL2 SGOL1 DCTN1 DHFR DNA2 DYNC1H1 DYNC1I2 DYRK1A E2F1 E2F2 E2F3 E2F4 E2F5 TUBB SKA1 FEN1 CEP164 MAPRE1 NINL AZI1 PSME4 CLASP1 ITGB3BP ORC6 ORC3 POLA2 CDC26 CENPI AHCTF1 NSL1 FBXO5 TUBG2 PPP2R3B LIN9 ANAPC2 RPA4 ANAPC4 HDAC1 BIRC5 HSP90AA1 SKA2 NUP43 INCENP APITD1 KIF2A LIG1 CENPP MAD2L1 MAX MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MNAT1 LOC440917 LOC441488 MYBL2 MYC NEK2 NUMA1 ORC1 ORC2 ORC4 ORC5 PAFAH1B1 GMNN PCM1 PCNA PCNT ANAPC5 ANAPC7 ANAPC11 GINS2 PLK1 POLA1 POLD1 POLD2 POLE POLE2 ERCC6L CCDC99 PPP1CC ZWILCH CEP192 HAUS2 CDCA8 PPP2CA PPP2CB CENPQ PPP2R1A PPP2R1B PPP2R2A PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E MCM10 PRIM1 PRIM2 PRKACA CEP72 NUP133 CDK5RAP2 PRKAR2B CENPJ CENPN RCC2 LIN37 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 CASC5 PSMD3 PSMD4 PSMD5 NUP107 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 SPC25 TAOK1 POLD4 RAD21 RANBP2 RANGAP1 RB1 RBBP4 RBL1 RBL2 CCND1 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 RPS27 RPS27A RRM2 CLIP1 SEC13 CENPK RBBP4P1 DHFRP1 LOC645084 ANAPC1 GORASP1 TUBBP2 LOC647654 CENPH LOC649620 SKP1 SKP2 LOC650621 LOC651763 LOC652826 AURKA BUB1 BUB1B TFDP1 TK2 TUBA4A TUBG1 RPS27AP11 SKA2L TYMS CDC26P1 LOC729964 LOC730418 LOC730594 UBA52 UBE2D1 UBE2E1 WEE1 XPO1 YWHAE YWHAG ALMS1 TUBA1A MIS12 CENPM NUP37 CENPO MLF1IP NUP85 CEP76 DSN1 CENPT CEP290 CEP63 CEP70 B9D2 NDEL1 CDT1 SEH1L KIF18A SMC1A CDC7 CDC45 NUF2 MAD1L1 GINS4 MCM8 CUL1 KIF2B OFD1 TUBGCP6 CDC14A SSNA1 DYNLL1 CDC23 CDC16 CCNA2 CCNA1 CCNB1 CCND2 BTRC CCND3 CCNE1 CCNH PKMYT1 SMC3 CCNB2 CCNE2 CENPL LIN52 ZW10 BUB3 AURKB PTTG1 PSMF1 KIF23 CEP41 CEP135 CEP57 KNTC1 CKAP5 CDK1 GINS1 PSMD6 CDC6 CDC20 CDC25A CDC25B CDC25C CDC27 +REACTOME_GLUCONEOGENESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLUCONEOGENESIS SLC25A13 SLC25A10 ENO1 ENO2 ENO3 FBP1 ALDOA ALDOB ALDOC GAPDH GAPDHS GOT1 GOT2 GPI MDH1 MDH2 PC PCK1 PCK2 PFKFB1 PGAM1 PGAM2 PGK1 PRKACA PRKACB PRKACG LOC642969 SLC25A1 TPI1 TPI1P1 LOC730418 SLC25A11 SLC25A12 FBP2 +REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE RIMS1 RAB3A SLC18A2 SNAP25 STX1A STXBP1 VAMP2 SYN1 SYN2 SYT1 SYN3 +REACTOME_OPIOID_SIGNALLING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_OPIOID_SIGNALLING CDK5 GNB5 ADCY1 ADCY2 ADCY3 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 CREB1 ADRBK1 ADCY4 PLCB1 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAT1 GNAT2 GNAZ GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 ITPR2 ITPR3 OPRM1 PDE1A PDE4B PDE4C PDE4D PDE1B PDYN GNG13 PLA2G4A PLCB2 PLCB3 PLCB4 GNG2 POMC PPP1CA PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D PPP3CA PPP3CB PPP3R1 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCD PRKCG MAPK1 GNG12 GNB4 LOC730418 CALM1 CALM2 CALM3 CAMK4 PPP1R1B GNG8 +REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES ACTR1A AKAP9 TUBB4A TUBB4B TUBGCP3 DCTN2 CETN2 PLK4 SDCCAG8 TUBGCP2 CNTRL FGFR1OP CEP250 DCTN3 TUBGCP5 NEDD1 CSNK1D CSNK1E DCTN1 DYNC1H1 DYNC1I2 TUBB CEP164 MAPRE1 NINL AZI1 CLASP1 TUBG2 HSP90AA1 LOC440917 NEK2 NUMA1 PAFAH1B1 PCM1 PCNT PLK1 CEP192 HAUS2 PPP2R1A PRKACA CEP72 CDK5RAP2 PRKAR2B CENPJ TUBBP2 TUBA4A TUBG1 LOC730418 YWHAE YWHAG ALMS1 TUBA1A CEP76 CEP290 CEP63 CEP70 OFD1 TUBGCP6 SSNA1 DYNLL1 CCNB1 CEP41 CEP135 CEP57 CKAP5 CDK1 +REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION WARS2 FARS2 EARS2 LARS2 HARS2 PARS2 GARS PPA2 KARS YARS2 SARS2 DARS2 IARS2 RARS2 VARS2 AARS2 QARS CARS2 NARS2 TARS2 MARS2 +REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION FARSB AARS DARS EPRS FARSA GARS HARS IARS KARS MARS NARS LARS PPA1 QARS RARS SARS TARS VARS WARS AIMP2 CARS YARS AIMP1 EEF1E1 +REACTOME_CA_DEPENDENT_EVENTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CA_DEPENDENT_EVENTS ADCY1 ADCY2 ADCY3 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 CREB1 ADRBK1 ADCY4 PDE1A PDE1B PLA2G4A PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCD PRKCG MAPK1 LOC730418 CALM1 CALM2 CALM3 CAMK4 +REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE CHAT RIMS1 RAB3A SLC5A7 SLC18A3 SNAP25 STX1A STXBP1 VAMP2 SYT1 +REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY ADCY1 ADCY2 ADCY3 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADCY4 GNAL +REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY ADCY1 ADCY2 ADCY3 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADCY4 GNAI1 GNAI2 GNAI3 GNAL +REACTOME_DARPP_32_EVENTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DARPP_32_EVENTS CDK5 PDE4B PDE4C PDE4D PPP1CA PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D PPP3CA PPP3CB PPP3R1 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B LOC730418 CALM1 CALM2 CALM3 PPP1R1B +REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES CXCL13 CXCR6 CCR9 CCL27 CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCBP2 CX3CR1 CCR10 XCR1 CXCR3 CXCL1 CXCL2 CXCL3 IL8 CXCR1 CXCR2 CXCL10 CCL3L3 CXCL9 CCRL1 PF4 PPBP CCL28 CXCR7 CXCL16 CCL2 CCL3 CCL3L1 CCL4 CCL5 CCL7 CCL11 CCL16 CCL17 CCL19 CCL20 CCL21 CCL22 CCL25 CXCL6 CXCL11 CXCL5 XCL1 CX3CL1 CXCL12 CXCR5 CCRL1P1 XCL2 LOC728830 CXCR4 +REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES ACTR1A AKAP9 TUBB4A TUBB4B DCTN2 CETN2 PLK4 SDCCAG8 CNTRL FGFR1OP CEP250 DCTN3 NEDD1 CSNK1D CSNK1E DCTN1 DYNC1H1 DYNC1I2 TUBB CEP164 MAPRE1 NINL AZI1 CLASP1 HSP90AA1 LOC440917 NEK2 PAFAH1B1 PCM1 PCNT PLK1 CEP192 HAUS2 PPP2R1A PRKACA CEP72 CDK5RAP2 PRKAR2B CENPJ TUBBP2 TUBA4A TUBG1 LOC730418 YWHAE YWHAG ALMS1 TUBA1A CEP76 CEP290 CEP63 CEP70 OFD1 SSNA1 DYNLL1 CEP41 CEP135 CEP57 CKAP5 CDK1 +REACTOME_NEUROTRANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE_POSTSYNAPTIC_CELL http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEUROTRANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE_POSTSYNAPTIC_CELL AKAP9 CACNG3 CACNG2 GNB5 ADCY1 ADCY2 ADCY3 ADCY5 ADCY6 ADCY7 CHRNA1 CHRNA2 CHRNA3 CHRNA4 CHRNA5 CHRNA7 ADCY8 CHRNB2 CHRNB3 CHRNB4 CHRND CHRNE CHRNG ADCY9 AP2M1 AP2S1 CREB1 AP2A1 AP2A2 AP2B1 DLG1 DLG3 ADCY4 EPB41L1 ARHGEF9 PLCB1 GABBR1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRG2 GABRG3 GABRR1 GABRR2 CACNG4 RPS6KA6 GNAI1 GNAI2 GNAI3 GNAL GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GRIA1 GRIA2 GRIA3 GRIA4 GRIK1 GRIK2 GRIK3 GRIK4 GRIK5 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D HRAS KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6 KCNJ9 KCNJ10 KCNJ12 KCNJ15 KCNJ16 MDM2 MYO6 NEFL NSF PDPK1 GNG13 PLCB2 PLCB3 GNG2 CHRNA9 PRKACB PRKCA PRKCB PRKCG MAPK1 GNG12 RAF1 RASGRF1 RASGRF2 CACNG8 GNB4 RPS6KA1 RPS6KA2 RPS6KA3 RRAS LOC651907 BRAF LOC732445 CALM1 CALM2 CALM3 GRIP2 CAMK4 CAMK2A CAMK2B CAMK2D NCALD CAMKK1 ACTN2 CHRNA6 CHRFAM7A GNG8 PICK1 AKAP5 GABBR2 +REACTOME_CELL_CYCLE_CHECKPOINTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_CYCLE_CHECKPOINTS CDK2 PSMD14 CDKN1A CDKN1B ANAPC10 DBF4 UBE2C CHEK1 CHEK2 PSMA8 PSME4 ORC6 ORC3 CDC26 ANAPC2 ANAPC4 HUS1 MAD2L1 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MDM2 ATM ORC1 ORC2 ORC4 ORC5 ANAPC5 ANAPC7 ANAPC11 ATR MCM10 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RAD1 RAD9A RAD17 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 RPS27A RFWD2 LOC645084 ANAPC1 LOC647654 LOC648152 LOC649620 LOC650621 LOC651610 LOC651763 LOC651921 LOC652826 BUB1B TP53 RPS27AP11 RFWD2P1 CDC26P1 LOC730594 UBA52 UBE2D1 UBE2E1 WEE1 CDC7 CDC45 MAD1L1 ATRIP MCM8 CDC23 CDC16 CCNB1 CCNE1 CCNB2 CCNE2 BUB3 PSMF1 CDK1 PSMD6 CDC6 CDC20 CDC25A CDC25C CDC27 +REACTOME_DIABETES_PATHWAYS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DIABETES_PATHWAYS CTDSP2 PREB PDIA6 HYOU1 EXOC5 IGF2BP1 IGF2BP3 IGF2BP2 YIF1A PDIA5 KDELR3 EXOC3 EXOSC8 KLHDC3 ADD1 EXOSC6 TPP1 CPE SLC30A7 EXOC8 CTSG DCTN1 DDIT3 DDX11 DCP2 EIF2S1 ERN1 EXTL3 F2 SEC31A DIS3 ATF6 EXOSC7 EXOSC2 SEC11A GCG GH1 SERP1 SPCS1 GSK3A ERO1L HDGF CXXC1 HSPA5 IGF2 IGFALS IGFBP1 IGFBP2 IGFBP3 IGFBP4 IGFBP5 IGFBP6 KLK3 IL8 INS ACADVL KIF5B LEP LMNA DNAJB9 MMP1 MMP2 ASNS DDX12P SULT1A4 MYO5A ATF3 ATF4 NFYA NFYB PAPPA PARN EXOSC3 EXOSC1 PCSK1 PCSK2 MBTPS2 DNAJB11 GHRL PLG EXOSC9 EXOSC4 EXOC6 FKBP14 WIPI1 PPP2R5B ARFGAP1 EXOC1 EXOC2 C19orf10 DNAJC3 EXOSC5 SRPRB RAB27A BCHE EXOC4 SPCS3 PAPPA2 MBOAT4 CCL2 TSPYL2 ATF4P3 LOC644556 SHC1 SLC30A5 LOC653566 SNAP25 SRPR SSR1 STX1A SULT1A3 VAMP2 TLN1 HSP90B1 LOC730136 WFS1 XBP1 ZBTB17 PLA2G7 CALR SYVN1 KHSRP MBTPS1 SEC11C ATP6V0D1 KLF4 EIF2AK3 GOSR2 EDEM1 HERPUD1 SPCS2 TATDN2 CUL7 +REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS CRK FGA FGB FGG FN1 ITGA2B ITGB3 APBB1IP PTK2 RAP1A RAP1B SRC TLN1 VWF BCAR1 +REACTOME_GLYCOPROTEIN_HORMONES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLYCOPROTEIN_HORMONES CGA CGB FSHB INHA INHBA INHBB INHBC LHB TSHB INHBE CGB5 CGB8 +REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE RIMS1 MAOA RAB3A SLC18A2 SLC22A2 SNAP25 STX1A STXBP1 VAMP2 SYT1 +REACTOME_PLC_BETA_MEDIATED_EVENTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PLC_BETA_MEDIATED_EVENTS ADCY1 ADCY2 ADCY3 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 CREB1 ADRBK1 ADCY4 PLCB1 GNAI1 GNAI2 GNAI3 GNAO1 GNAT1 GNAT2 GNAZ ITPR2 ITPR3 PDE1A PDE1B PLA2G4A PLCB2 PLCB3 PLCB4 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCD PRKCG MAPK1 LOC730418 CALM1 CALM2 CALM3 CAMK4 +REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS CTSG F2 IGF2 IGFALS IGFBP1 IGFBP2 IGFBP3 IGFBP4 IGFBP5 IGFBP6 KLK3 MMP1 MMP2 PAPPA PLG PAPPA2 +REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ FGA FGB FGG FN1 GRB2 ITGA2B ITGB3 APBB1IP PTK2 RAP1A RAP1B SOS1 SRC TLN1 VWF +REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS CGA CGB FSHB INHA INHBA INHBB INHBC LHB PCSK1 POMC TSHB INHBE CGB5 CGB8 +REACTOME_G_PROTEIN_ACTIVATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G_PROTEIN_ACTIVATION GNB5 GNAI1 GNAI2 GNAI3 GNAO1 GNAT1 GNAT2 GNAZ GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 OPRM1 PDYN GNG13 GNG2 POMC GNG12 GNB4 GNG8 +REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS CHRNA1 CHRNA2 CHRNA3 CHRNA4 CHRNA5 CHRNA7 CHRNB2 CHRNB3 CHRNB4 CHRND CHRNE CHRNG CHRNA9 LOC732445 CHRNA6 CHRFAM7A +REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT ABCC5 ABCB6 ABCC9 ABCC4 ABCA7 ABCA10 ABCA9 ABCA8 CFTR ABCC2 ABCA2 ABCA3 ABCD1 ABCD2 ABCB10 ABCA6 ABCA4 ABCA12 APOA1 ABCB5 ABCC6 ABCC1 ABCB1 PEX19 ABCD3 ABCG4 ABCG5 ABCG8 ABCD1P5 ABCC8 PEX3 ABCC11 ABCC3 ABCG1 +REACTOME_TRNA_AMINOACYLATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRNA_AMINOACYLATION FARSB WARS2 FARS2 EARS2 AARS DARS EPRS FARSA LARS2 HARS2 PARS2 GARS PPA2 HARS IARS KARS MARS NARS YARS2 LARS PPA1 SARS2 DARS2 IARS2 RARS2 VARS2 AARS2 QARS RARS SARS TARS VARS WARS CARS2 AIMP2 NARS2 TARS2 CARS YARS AIMP1 MARS2 EEF1E1 +REACTOME_OLFACTORY_SIGNALING_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_OLFACTORY_SIGNALING_PATHWAY OR5I1 OR52E2 OR52J3 OR51L1 OR51A7 OR51S1 OR51F2 OR52R1 OR4X2 OR4B1 OR52M1 OR52K2 OR5P2 OR5P3 OR8I2 OR2D3 OR2D2 OR52W1 OR56A4 OR56A1 OR10P1 OR10AD1 OR10A7 OR4K14 OR4L1 OR4D2 OR7D4 OR7G1 OR1M1 OR1I1 OR10H4 OR2M5 OR2M3 OR2T12 OR14C36 OR2T34 OR2T10 OR2T4 OR2T11 OR10J5 OR2B11 OR10T2 OR10X1 OR10Z1 OR6K6 OR6N1 OR9A4 OR2Y1 OR9A2 OR2A14 OR6B1 OR2F2 OR1L8 OR1N2 OR1N1 OR52B4 OR52I2 OR51E1 OR10A5 OR2AG1 OR6B3 OR1Q1 OR7D2 OR56B4 OR8U1 OR4C16 OR4C11 OR4S2 OR4C6 OR5D14 OR5L1 OR5D18 OR5AS1 OR8K5 OR5T2 OR8H1 OR8K3 OR8J1 OR5R1 OR5M3 OR5M8 OR5AR1 OR8B12 OR10G8 OR10G9 OR10S1 OR6T1 OR4D5 OR6Q1 OR9I1 OR9Q1 OR9Q2 OR1S2 OR1S1 OR10Q1 OR5B17 OR5A2 OR5A1 OR4D6 OR4D11 OR52A1 OR6C3 OR1L4 OR4C3 OR4S1 OR1C1 OR1A2 OR2F1 OR2B6 OR1J4 OR2M4 OR2L2 OR2K2 OR7A17 OR5L2 OR5K1 OR10J1 OR8B8 OR10A3 OR11A1 OR10H3 OR10G3 OR10G2 OR10H2 OR10H1 OR7C2 OR7A5 OR7C1 OR4F4 OR4F3 OR4E2 OR4D1 OR2W1 OR2T1 OR2H1 OR1L3 OR1L1 OR1J2 GNAL GNB1 GNGT1 OR51B5 OR10AG1 OR5J2 OR4C13 OR4C12 OR51V1 OR8D1 OR8D2 OR8B4 OR9G4 OR10A4 OR4N4 OR2Z1 OR10H5 OR2L13 OR14A16 OR2V2 OR8D4 OR5F1 OR5AP2 OR52L1 OR52B6 OR10A2 OR6C2 OR6C4 OR8S1 OR6S1 OR6F1 OR14K1 OR2W3 OR2T3 OR10R2 OR2T29 OR6V1 OR2A12 OR2A1 OR1J1 OR1B1 OR56B1 OR6B2 OR52K1 OR52I1 OR51D1 OR52A5 OR51B6 OR51M1 OR51Q1 OR51I1 OR51I2 OR52D1 OR52H1 OR52N4 OR52N5 OR52N2 OR52E6 OR52E8 OR52E4 OR56A3 OR10A6 OR4X1 OR5D13 OR5D16 OR5W2 OR8H2 OR8H3 OR5T3 OR5T1 OR8K1 OR5M9 OR9G1 OR5AK2 OR5B2 OR5B12 OR5AN1 OR4D9 OR10V1 OR6X1 OR6M1 OR10G4 OR10G7 OR8B3 OR8A1 OR6C1 OR4N2 OR4K2 OR4K13 OR4K17 OR4N5 OR11G2 OR5AU1 OR4M2 OR4F6 OR4F15 OR3A4P OR7G2 OR7G3 OR7A10 OR10K2 OR10K1 OR6Y1 OR6K3 OR2L8 OR2AK2 OR2L3 OR2M2 OR2T33 OR2M7 OR2G6 OR2A25 OR1L6 OR5C1 OR1K1 OR2A5 OR2A7 OR51T1 OR51A4 OR51A2 OR2T2 OR2T5 OR5K2 OR2A42 OR2T27 OR2T35 OR4A47 OR5B3 OR9K2 OR4Q3 OR4M1 OR10J3 OR2B3 OR2J3 OR14J1 OR10C1 OR2A2 OR1D2 OR1F1 OR2C1 OR3A1 OR3A2 OR8U8 OR8U9 OR9G9 OR2S2 OR4N3P LOC652692 OR4F29 LOC730421 LOC730808 OR5H6 OR5H2 OR4K5 OR51G1 OR51B4 OR51B2 OR52N1 OR4F5 OR2A4 OR4K1 OR5AC2 OR4F17 OR4K15 OR8J3 OR51G2 OR51E2 OR4P4 OR4C15 OR4A5 OR4A16 OR4A15 OR10W1 OR2AE1 OR4F16 OR6N2 OR6K2 OR2G3 OR2G2 OR2C3 OR5V1 OR2B2 OR1A1 OR1D4 OR1D5 OR1E1 OR1E2 OR1G1 OR3A3 OR6A2 +REACTOME_STEROID_HORMONES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_STEROID_HORMONES CGA CYP2R1 STARD4 STARD6 CYP11A1 CYP11B1 CYP11B2 CYP17A1 CYP19A1 CYP21A2 CYP24A1 CYP27B1 AKR1B1 GC HSD3B1 HSD3B2 HSD11B1 HSD17B1 HSD17B3 LHB LRP2 POMC LGMN SRD5A1 SRD5A2 STAR SRD5A3 CUBN STARD5 +REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB ADCY1 ADCY2 ADCY3 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 CREB1 ADCY4 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B LOC730418 +REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES TUBGCP3 TUBGCP2 TUBGCP5 NEDD1 TUBG2 NUMA1 TUBG1 TUBGCP6 CCNB1 CDK1 +REACTOME_AMINE_DERIVED_HORMONES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AMINE_DERIVED_HORMONES CGA TPH2 AANAT DBH DDC DIO1 DIO2 DIO3 IYD PNMT SLC5A5 TH TPH1 TPO TSHB +REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES ABCC5 ABCB6 ABCC9 ATP9A ABCC4 TCIRG1 ABCA7 ABCA10 ABCA9 ABCA8 ATP8A1 SLC9A6 SLC35A1 SLC34A2 SLCO1B1 GNB5 ADCY1 SLC12A7 NUP50 ADCY2 CFTR SLC26A1 SLC22A7 ADCY3 SLC38A3 SLC27A4 SLC35D2 NUPL2 ADCY5 SLC7A9 SLC2A6 ADCY6 SLC6A14 ADCY7 SLCO2B1 SLC46A1 ADCY8 SLC2A13 ADCY9 SLC26A9 SLC26A7 SLC5A11 SLC22A12 SLC16A10 SLC15A4 SLC24A4 ABCC2 SLC43A2 SLC44A3 ATP6V1G3 NUP35 SLC31A1 CP SLC32A1 SLC34A3 SLC25A10 SLC47A2 ATP8B3 SLC30A7 SLC36A2 SLC2A12 SLC2A7 SLC5A8 SLC30A8 HTR3C SLC26A3 SLC26A2 ADCY4 ABCA2 SLC29A1 SLC44A5 SLC36A1 ABCA3 ALB ABCD1 SLC29A4 ABCD2 RAB11FIP2 ATP10B NUP205 SLC35D1 ATP11B NUP210 ARHGEF9 ATP11A SLC9A8 SLC7A8 SLC35A3 SLC44A1 ABCB10 ABCA6 NUP188 SLC16A8 ATP6V0A2 NUP62 SLC7A11 ABCA4 ATP6V0D2 ATP6V1C2 SLC17A8 FTH1 FTL G6PC SLC37A4 SLC41A1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRG2 GABRG3 GABRR1 GABRR2 SLC24A2 SLC39A6 ABCA12 GCK GCKR SLC17A5 ATP2C1 SLC39A1 GLRA1 GLRA2 GLRB GNAS GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 SLCO4A1 SLCO3A1 SLCO1B3 SLC39A5 SLC24A5 SLC13A5 SLC9A9 ATP11C SLC27A6 FLVCR1 SLC39A3 SLC39A2 SLC2A8 SLC40A1 HK1 HK2 HK3 HMOX1 HMOX2 SLC29A2 APOA1 HTR3A SLC6A19 ABCB5 AQP8 SLC10A6 SLC35B2 SLC6A18 NUP43 SLCO4C1 AQP1 AQP2 AQP3 AQP4 AQP5 AQP6 AQP7 AQP9 ABCC6 ATP9B SLC27A1 SLC9A4 MIP ABCC1 MYO5B ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4 ATP1B1 ATP1B2 ATP1B3 FXYD2 ATP2A1 ATP2A2 ATP2A3 ATP2B2 ATP2B3 NUP88 ATP4A ATP4B SLC22A18 ATP6V0A4 SLC15A3 ATP6V1D RHCG ATP6V1H SLC26A4 ATP8A2 GNG13 ATP8B1 ATP6V1A ABCB1 ATP6V1B1 ATP6V1B2 ATP6V0C ATP6V1C1 ATP6V1E1 ATP6V0B NUP54 ATP6V1G2 ATP7A SLCO1C1 ATP7B GNG2 SLC38A2 SLC6A20 SLC38A4 AVP SLC6A15 STEAP3 SLC47A1 SLC29A3 SLC35C1 SLC22A15 AVPR2 SLC39A4 PRKACA PRKACB PRKACG PRKAR1A NUP133 PRKAR1B PRKAR2A PRKAR2B SLC22A11 GNG12 SLC7A10 SLC2A9 SLC17A7 SLC17A6 NUP107 SLC44A2 SLC39A10 MCOLN1 ATP10A ATP10D SLC24A3 SLC12A5 G6PC2 SLC4A5 PEX19 ABCD3 RANBP2 GNB4 RHAG SLC5A7 SLC28A3 SLC39A8 ABCG4 ABCG5 ABCG8 ABCD1P5 LOC644732 SLC13A3 SLC30A5 SLC26A6 SLC1A1 SLC1A2 SLC1A3 SLC4A3 SLC1A4 SLC1A5 SLC1A6 SLC1A7 SLC2A1 SLC2A2 SLC2A3 SLC2A4 SLC2A5 SLC3A1 SLC3A2 SLC4A1 SLC4A2 SLC5A1 SLC5A2 SLC5A3 LOC652661 SLC5A5 SLC6A1 SLC6A2 SLC6A3 SLC6A6 SLC6A7 SLC6A9 SLC6A11 SLC6A12 SLC7A1 SLC7A2 SLC8A2 SLC8A1 SLC8A3 SLC9A1 SLC9A2 SLC9A3 SLC9A5 SLC11A1 SLC12A1 SLC12A2 SLC12A4 SLC13A1 SLC14A1 SLC15A1 SLC15A2 SLC16A1 SLC17A1 SLC34A1 SLC18A1 SLC18A2 SLC20A1 SLC20A2 SLCO2A1 SLCO1A2 SLC22A1 SLC22A3 SLC22A2 SLC22A4 SLC22A5 SLC2A11 ABCC8 TF TFRC TPR LOC730418 SLC35A2 SLC30A1 SLC30A2 SLC30A3 NUP37 SLC39A7 ATP8B4 CYBRD1 NUP85 GLRA3 SLC24A6 NUP214 SLC44A4 AAAS SLC2A10 SLC7A5 SLC38A1 SLC14A2 SEH1L SLC4A9 SLC41A2 SLC9A7 RAE1 SLC7A3 SLC35B4 SLC43A1 PEX3 ABCC11 SLC22A16 SLC4A4 ABCC3 RAB11A SLC5A6 AQP10 ATP6V0E1 ATP6V1E2 SLC7A7 SLC7A6 SLC13A2 ATP6V0D1 SLC16A3 SLC6A5 SLC28A2 SLC28A1 HTR3B SLC24A1 SLC16A7 SLC33A1 G6PC3 SLC38A5 ATP6V1F SLC22A6 SLC22A8 GNG8 ABCG2 SLC4A7 SLC4A8 ATP6V1G1 ABCG1 NUP155 NUP93 NUPL1 HEPH POM121 ATP2C2 NUP153 SLC12A6 +REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING RASGRP1 RASGRP2 RAPGEF3 RAPGEF4 CRK CSK AKT1 FGA FGB FGG FN1 GRB2 ITGA2B ITGB3 PDPK1 APBB1IP PTK2 PTPN1 RAP1A RAP1B SHC1 SOS1 SRC SYK TLN1 VWF BCAR1 +REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY NR2E3 NR1H3 NR2C2AP NR0B1 NR2F6 ESR1 ESR2 ESRRA ESRRB ESRRG NR5A2 NR5A1 NR6A1 NR3C1 NRBP1 NRBF2 NR4A1 HNF4A HNF4G AR NR3C2 NR4A2 PGR PPARA PPARD PPARG MED1 RARA RARG RORA RORB RORC RXRA RXRB RXRG NR2F1 THRA THRB NR2E1 LOC728381 LOC731106 NR1H2 VDR NR4A3 NR0B2 NR1I2 NR1D1 NR1I3 NR1D2 +REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING EXOC5 EXOC3 CPE SLC30A7 EXOC8 ERO1L INS KIF5B MYO5A PCSK1 PCSK2 EXOC6 EXOC1 EXOC2 RAB27A EXOC4 LOC644556 SLC30A5 SNAP25 STX1A VAMP2 +REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ CDK2 PSMD14 CDK7 CDKN1A CDKN1B CKS1B MAX MNAT1 MYC PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RB1 RPS27A SKP1 SKP2 LOC652826 RPS27AP11 LOC729964 UBA52 WEE1 CUL1 CCNA2 CCNA1 CCNE1 CCNH PKMYT1 CCNE2 PSMF1 PSMD6 CDC25A +REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS RAD50 H2AFX LIG1 MRE11A NBN ATM RAD51 RAD52 RPA1 RPA2 RPA3 LOC651610 BRCA1 BRCA2 TP53BP1 BRIP1 MDC1 +REACTOME_G1_PHASE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G1_PHASE CDK4 CDK6 CDK7 CDKN1A CDKN1B CDKN2A CDKN2B CDKN2C CDKN2D CKS1B E2F1 E2F2 E2F3 E2F4 E2F5 PPP2R3B MNAT1 LOC441488 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A RB1 RBL1 RBL2 CCND1 RPS27A SKP1 SKP2 TFDP1 RPS27AP11 LOC729964 UBA52 CUL1 CCND2 CCND3 CCNH +REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS ITPR2 ITPR3 P2RX1 TRPC7 STIM1 TRPC3 TRPC6 LOC730221 LOC730335 ORAI1 +REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE CDK2 PSMD14 CDKN1A CDKN1B PSMA8 PSME4 MDM2 ATM PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RPS27A RFWD2 LOC651610 LOC652826 TP53 RPS27AP11 RFWD2P1 UBA52 CCNE1 CCNE2 PSMF1 PSMD6 +REACTOME_TRANSCRIPTION_COUPLED_NER_TC_NER http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSCRIPTION_COUPLED_NER_TC_NER CDK7 POLD3 ERCC8 ERCC1 ERCC2 ERCC3 ERCC4 ERCC5 ERCC6 GTF2H1 GTF2H2 GTF2H3 GTF2H4 LIG1 MNAT1 PCNA POLD1 POLD2 POLE POLE2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L XAB2 POLD4 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 LOC652857 GTF2H2B TCEA1 CCNH +REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING CDK7 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 MNAT1 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L LOC652857 GTF2H2B TAF1 TAF4 TAF4B TAF5 TAF6 TAF9 TAF10 TAF11 TAF12 TAF13 TBP CCNH +REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION ADCY1 ADCY2 ADCY3 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADCY4 GCG GCGR GNAS GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNG13 GNG2 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B GNG12 GNB4 LOC730418 GNG8 +REACTOME_MRNA_PROCESSING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MRNA_PROCESSING RBM5 THOC4 CDK7 HNRNPR SRRM1 SF3B4 SF3A1 ADAR ADARB1 CD2BP2 NXF1 PRPF8 NUP50 TXNL4A PAPOLA RNPS1 SF3A3 HNRNPA0 CLP1 SF3B2 NUDT21 NUPL2 HNRNPUL1 U2AF2 SNRPD2P1 NUP35 LSM11 CSTF1 CSTF2 CSTF3 DHX9 EIF4E ERCC2 ERCC3 HNRNPA3 DNAJC8 NCBP2 SNRNP200 NUP205 NUP210 SF3B3 SF3B1 NUP188 NUP62 PRPF6 FUS ZNF473 RBMX GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 CPSF1 A1CF HNRNPA1 HNRNPA2B1 HNRNPC HNRNPD HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPL HNRNPU APOBEC1 NUP43 MAGOH MNAT1 HNRNPM NCBP1 NFX1 NHP2L1 YBX1 NUP88 PCBP1 PCBP2 CDC40 PCF11 SF3B14 CPSF3 NUP54 CPSF2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L NUP133 CCAR1 METTL3 NUP107 PTBP1 SUGP1 LSM2 RANBP2 SRSF1 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 LOC643446 UPF3B LOC652147 LOC652857 GTF2H2B LOC653889 SNRNP70 SNRPA SNRPA1 SNRPB SNRPB2 SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SUPT5H TPR U2AF1 SLBP NUP37 CPSF7 NUP85 NUP214 AAAS PABPN1 SF3A2 SEH1L SMC1A SF3B5 RAE1 PHF5A LSM10 SRSF9 RNMT RNGTT CCNH PRPF4 SRSF11 EFTUD2 SNRNP40 DDX23 NUP155 NUP93 DHX38 NUPL1 POM121 RBM8A NUP153 +REACTOME_SIGNALING_BY_PDGF http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_PDGF AKT3 CDKN1A CDKN1B ADCY1 ADCY2 ADCY3 ADCY5 ADCY6 ADCY7 ADCY8 CHUK ADCY9 THEM4 COL1A1 COL1A2 COL2A1 COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL5A1 COL5A2 COL6A1 COL6A2 COL6A3 COL9A1 COL9A2 COL9A3 CREB1 CRK CRKL ADRBK1 ADCY4 AKT1 AKT2 FOXO1 FOXO3 PHLPP1 MTOR RICTOR GRB2 GRB7 RAPGEF1 GSK3A NR4A1 HRAS ITPR2 ITPR3 KRAS MDM2 FOXO4 NCK1 NRAS FURIN PDE1A PDE1B PDGFA PDGFB PDGFRA PDGFRB PDPK1 PIK3CA PIK3CB PIK3R1 PIK3R2 PLAT PLCG1 PLG PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCD PRKCE PRKCG MAPK1 MAPK3 PDGFC MAP2K1 MAP2K2 BAD PTEN TRIB3 RAF1 RASA1 RPS6KB2 MLST8 SOS1 SPP1 SRC STAT1 STAT3 STAT5A STAT5B STAT6 THBS1 THBS2 THBS3 THBS4 TSC2 LOC729030 LOC729120 LOC730418 LOC731292 YWHAB MAPKAP1 CALM1 PDGFD CALM2 CALM3 CAMK4 CASP9 AKT1S1 NCK2 BCAR1 CDK1 +REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS NOP56 ARFGEF2 CCT7 CCT4 CCT2 CCT8 FKBP9 XRN2 CCT5 FBXW2 FBXL3 FBXL5 FBXO6 FBXO4 AP3M1 KIFC3 FBXW5 FBXW7 KIF13A FBXW4 TCP1 CCT3 LOC732391 USP11 LONP2 SPHK1 CCT6A +REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC TUBB3 TUBB4A TUBB4B PFDN6 CCT7 CCT4 CCT2 CCT8 TUBA3D CCT5 TUBB2B PFDN1 PFDN2 PFDN4 PFDN5 ACTB LOC654264 TCP1 CCT3 TUBA4A TUBA3C TUBB2A VBP1 TUBA1A TUBB1 TUBB6 TUBA1C CCT6A +REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS CGA FSHB FSHR GNRH1 GNRH2 GNRHR LHB LHCGR TSHB TSHR +REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE AKT3 VAV3 COL1A1 COL1A2 PIK3R6 AKT1 AKT2 FCER1G PIK3R5 FYN LAT RHOA RHOB RHOG LCK LCP2 LYN PDPK1 PIK3CA PIK3CB PIK3CG PIK3R1 PIK3R2 PLCG2 PRKCZ RAC1 RAC2 SYK VAV1 PIK3R3 CDC42 +REACTOME_PROTEIN_FOLDING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROTEIN_FOLDING TUBA1B TUBB3 TUBB4A TUBB4B PFDN6 NOP56 ARFGEF2 CCT7 CCT4 CCT2 CCT8 FKBP9 TUBA3D TBCB XRN2 CCT5 FBXW2 FBXL3 FBXL5 FBXO6 FBXO4 AP3M1 TUBB2B KIFC3 PFDN1 PFDN2 PFDN4 PFDN5 FBXW5 FBXW7 ACTB KIF13A FBXW4 LOC654264 TBCA TBCC TBCD TBCE TCP1 CCT3 TUBA4A TUBA3C TUBB2A LOC732391 VBP1 TUBA1A TUBB1 USP11 LONP2 TUBB6 TUBA1C SPHK1 CCT6A +REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC TUBA1B TUBB3 TUBB4A TUBB4B CCT7 CCT4 CCT2 CCT8 TUBA3D CCT5 TUBB2B LOC654264 TCP1 CCT3 TUBA4A TUBA3C TUBB2A TUBA1A TUBB1 TUBB6 TUBA1C CCT6A +REACTOME_PEROXISOMAL_LIPID_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PEROXISOMAL_LIPID_METABOLISM ACOT8 SLC25A17 SLC27A2 CRAT ABCD1 AMACR HACL1 ACAA1 HSD17B4 IDH1 ACOX1 PHYH CROT FAR2 SCP2 ABCD1P5 ACOX2 ACOX3 FAR1 GNPAT AGPS +REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY TUBA1B TUBB3 TUBB4A TUBB4B TUBA3D TBCB TUBB2B LOC654264 TBCA TBCC TBCD TBCE TUBA4A TUBA3C TUBB2A TUBA1A TUBB1 TUBB6 TUBA1C +REACTOME_STRIATED_MUSCLE_CONTRACTION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_STRIATED_MUSCLE_CONTRACTION DES DMD MYBPC1 MYBPC2 MYH3 MYH6 MYH8 MYL1 MYL2 MYL3 MYL4 NEB TMOD1 TNNC2 TNNC1 TNNI1 TNNI2 TNNI3 TNNT1 TNNT2 TPM1 TPM2 TPM3 TPM4 VIM TCAP ACTN2 +REACTOME_METABOLISM_OF_NUCLEOTIDES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_NUCLEOTIDES ADA PAICS ADSSL1 ADK CTPS UPP2 ADSL ADSS ADAL DCK DCTD DGUOK DHODH DPYD DPYS DTYMK DUT TYMP AK1 AK2 NT5C2 GART AK5 AMPD1 AMPD2 AMPD3 GLRX GMPR GPX1 GSR GUK1 NT5C HPRT1 APRT IMPDH1 IMPDH2 ATIC NME1 NME2 NME4 PNP NT5E RRM2B NT5C3 GMPR2 CMPK1 UPB1 PFAS PPAT CTPS2 NT5M RRM1 RRM2 AGXT2 NME1-NME2 TK1 TK2 TXN TXNRD1 TYMS UCK2 UMPS UPP1 XDH CAD UCK1 NT5C1A CAT GMPS NT5C1B GDA CDA +REACTOME_AMINE_LIGAND_BINDING_RECEPTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AMINE_LIGAND_BINDING_RECEPTORS HRH3 CHRM1 CHRM2 CHRM3 CHRM5 TAAR1 ADRA1D ADRA1B ADRA1A ADRA2A ADRA2B ADRB1 ADRB2 ADRB3 DRD1 DRD2 DRD3 DRD5 TAAR6 HRH1 HRH2 HTR1A HTR1B HTR1D HTR1E HTR1F HTR2A HTR2B HTR2C HTR4 HTR5A HTR6 HTR7 HRH4 LOC730413 TAAR8 TAAR5 TAAR2 +REACTOME_METABOLISM_OF_PROTEINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_PROTEINS PIGK COX17 MUC12 PREB SLC25A13 ALG3 TIMM17B B3GNT3 TUBA1B TUBB3 TUBB4A TUBB4B SEC24B TIMM23B TIMM17A TOMM40 TIMM44 PFDN6 SEC23A NOP56 ARFGEF2 CCT7 CCT4 CCT2 ST6GALNAC2 MTX2 B3GNT2 CCT8 MAN1A2 SEC61B RPL35 GALNT6 GALNT5 MAN1B1 MGAT4B MGAT4A FKBP9 TUBA3D GALNT13 TBCB GALNTL2 MUCL1 EEF1DP1 PIGU DNAJC19 CHCHD4 GRPEL2 MUC17 CS MUC15 ALG10B B3GNTL1 HSCB RPL7AP27 ARSK CYC1 DAD1 DDOST TIMM8A GALNTL5 DHPS DPAGT1 EEF1A1 B3GNT6 EEF1B2 EEF1D EEF1G EEF2 EIF1AX EIF2S1 EIF2B1 EIF2S3 LDHD EIF4A1 EIF4A2 EIF4B EIF4E EIF4EBP1 EIF4G1 EIF5 EIF5A ALG14 ETF1 F2 F7 F9 F10 FAU XRN2 DOLK SEC31A ARSG CCT5 GANAB PMPCA TRAM1 SEC11A SEC61G RPL13A PIGN GSPT2 FXN FUT8 ST6GALNAC3 SAMM50 MGAT4C SUMF2 RPL36 GALNT1 GALNT2 GALNT3 FBXW2 FBXL3 FBXL5 FBXO6 FBXO4 GALNT8 GCNT1 FXC1 TIMM13 TIMM10 TIMM9 TIMM8B GFER GGCX B4GALT1 AP3M1 PABPC1 ST6GALNAC4 COQ2 EIF3K PIGW RPL10P16 SUMF1 LOC285407 FAM153A SPCS1 C1GALT1C1 C18orf55 SLC25A4 PDIA3 SLC25A6 ALG5 GMPPB GMPPA SEC61A1 TIMM22 ALG6 HSPA9 HSPD1 ST8SIA6 EIF3FP3 ARSI IDH3G RPL36P14 ARSH TUBB2B EIF3E STT3A GALNTL4 B3GNT8 KIFC3 RPSAP12 RPS8P10 RPL7AP66 RPL10P9 RPS12P4 RPSA MUC21 LMAN1 RPS26P10 TOMM5 RPL23AP2 ARSA ARSB STS MAN1A1 MAN2A1 ARSE ARSF MGAT1 MGAT2 MGAT3 MGAT5 MPI RPS12P22 ALG11 LOC440490 RPL21P29 RPS26P35 GALNTL6 MTX1 MUC2 MUC4 MUC5AC MUC6 MUC7 RPL10A ATP5A1 ACO2 FURIN ATP5B GALNT9 PAM16 ST8SIA3 RPL26L1 SAR1B PIGP GCNT4 ATP5G1 PIGT GALNT7 PFDN1 PFDN2 PFDN4 PFDN5 PGM3 PIGA PIGC PIGF PIGH PLAUR PMM1 PMM2 DPM3 FBXW5 TOMM7 PIGG PIGX SEC61A2 FBXW7 GALNT10 PIGV EDEM2 UGGT2 ALG13 PRKCSH ALG1 PROC PROS1 EIF5A2 MUC13 UGGT1 C1GALT1 TOMM22 MAN1C1 DOLPP1 GALNTL1 MUC3B SRPRB ACTB SPCS3 RPL3 RPL3L RPL4 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL10 RPL11 RPL12 RPL13 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL23A RPL24 RPL26 RPL27 RPL30 RPL27A RPL28 RPL29 RPL31 RPL32 RPL34 RPL35A RPL37 RPL37A RPL38 BCS1L RPL39 RPL41 RPL36A RPLP0 RPLP1 RPLP2 RPN1 RPN2 RPS2 RPS3 RPS3A RPS4X RPS4Y1 RPS5 RPS6 RPS7 RPS8 RPS9 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS18 RPS19 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS28 RPS29 GALNT11 SEC13 KIF13A RPL6P19 LOC647030 LOC641895 RPL36AP31 LOC642727 RPS29P3 RPS26P28 RPL36AP8 RPL26P22 WBSCR17 RPS26P20 GCNT6 LOC644589 RPS15AP11 RPS26P50 RPL22P11 RPL17P6 RPS13P8 RPS28P4 RPL32P16 LOC646184 RPS28P7 LOC646675 LOC646677 FBXW4 RPL12P2 LOC647074 RPL23AP42 RPL5P1 ST6GAL1 ST3GAL1 ST3GAL2 GNPNAT1 ST3GAL3 RPL36AP51 LOC649602 LOC650638 LOC650667 LOC650674 RPS28P9 RPL34P27 LOC651825 LOC651894 LOC652607 LOC652612 LOC652741 RPL26P30 RPSAP9 SRP9P1 RPL19P9 LOC653566 RPL21P119 RPL31P17 LOC653881 LOC653994 LOC654264 SRP9 SRP14 SRP19 SRP54 SRP68 SRP72 SRPR SSR1 SSR2 SSR3 SSR4 TAZ TBCA TBCC TBCD TBCE TCP1 CCT3 TUBA4A RPL31P31 TUBA3C MUC5B MUC19 TUBB2A RPL15P17 RPL23AP18 RPL26P24 RPL21P75 RPS27AP11 RPS26P7 RPL21P134 RPS26P25 RPS19P3 RPL36AP23 RPS18P10 RPL17P36 RPL36AP37 RPL21P16 RPL23AP74 RPS15P5 RPL23AP63 LOC729998 RPS10P9 LOC730343 RPS18P5 UBA52 RPL34P31 LOC732162 LOC732391 VBP1 VDAC1 EIF4H MOGS TUBA1A VKORC1 ALG8 ALG12 B3GNT4 GALNT14 ARSJ MANEA GALNT12 ALG9 TUSC3 SEMA6D PGAP1 EDEM3 GRPEL1 TUBB1 CALR ST8SIA2 CANX USP11 DOHH LONP2 B3GNT5 TUBB6 PIGO B3GNT9 TUBA1C ALG10 ALG2 SLC25A12 EIF3A EIF3B EIF3C EIF3D EIF3F EIF3G EIF3H EIF3I EIF3J B4GALT4 B4GALT3 B4GALT2 GPAA1 DPM1 DPM2 PROZ SPHK1 EIF2B4 EIF2B3 EIF2B2 EIF2B5 EIF2S2 MCFD2 RPL14 SEC11C CCT6A PIGQ RFT1 GCNT3 TIMM50 B3GNT7 PIGM B4GALT6 B4GALT5 RPL23 PIGS MUC16 PIGL PIGB PMPCB SEC24C EIF5B EDEM1 MLEC SPCS2 TOMM20 TOMM70A SEC24D GFPT2 +REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION AKT3 CDKN1A CDKN1B ADCY1 ADCY2 ADCY3 ADCY5 ADCY6 ADCY7 ADCY8 CHUK ADCY9 THEM4 CREB1 CRK CRKL ADRBK1 ADCY4 AKT1 AKT2 FOXO1 FOXO3 PHLPP1 MTOR RICTOR GRB2 GRB7 RAPGEF1 GSK3A NR4A1 HRAS ITPR2 ITPR3 KRAS MDM2 FOXO4 NCK1 NRAS PDE1A PDE1B PDGFA PDGFB PDGFRA PDGFRB PDPK1 PIK3CA PIK3CB PIK3R1 PIK3R2 PLCG1 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCD PRKCE PRKCG MAPK1 MAPK3 MAP2K1 MAP2K2 BAD PTEN TRIB3 RAF1 RASA1 RPS6KB2 MLST8 SOS1 SRC STAT1 STAT3 STAT5A STAT5B STAT6 TSC2 LOC729030 LOC729120 LOC730418 LOC731292 YWHAB MAPKAP1 CALM1 CALM2 CALM3 CAMK4 CASP9 AKT1S1 NCK2 BCAR1 CDK1 +REACTOME_MUSCLE_CONTRACTION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MUSCLE_CONTRACTION SORBS3 MYL12B MYL9 SORBS1 MYL6B DES DMD LMOD1 ITGA1 ITGB5 MYBPC1 MYBPC2 MYH3 MYH6 MYH8 MYH11 MYL1 MYL2 MYL3 MYL4 MYL6 MYLK NEB ACTA2 MYL8P LOC642076 TLN1 TMOD1 TNNC2 TNNC1 TNNI1 TNNI2 TNNI3 TNNT1 TNNT2 TPM1 TPM2 TPM3 TPM4 ACTG2 VCL VIM CALD1 CALM1 CALM2 CALM3 TCAP ACTN2 +REACTOME_SEROTONIN_RECEPTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SEROTONIN_RECEPTORS HTR1A HTR1B HTR1D HTR1E HTR1F HTR2A HTR2B HTR2C HTR4 HTR5A HTR6 HTR7 +REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX E2F1 E2F2 E2F3 ORC6 ORC3 ORC1 ORC2 ORC4 ORC5 MCM8 CDC6 +REACTOME_M_G1_TRANSITION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_M_G1_TRANSITION CDK2 PSMD14 DBF4 PSMA8 E2F1 E2F2 E2F3 PSME4 ORC6 ORC3 POLA2 RPA4 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 ORC1 ORC2 ORC4 ORC5 GMNN POLA1 POLE POLE2 MCM10 PRIM1 PRIM2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RPA1 RPA2 RPA3 RPS27A LOC645084 LOC652826 RPS27AP11 UBA52 CDT1 CDC7 CDC45 MCM8 PSMF1 PSMD6 CDC6 +REACTOME_MRNA_SPLICING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MRNA_SPLICING RBM5 THOC4 HNRNPR SRRM1 SF3B4 SF3A1 CD2BP2 PRPF8 TXNL4A PAPOLA RNPS1 SF3A3 HNRNPA0 CLP1 SF3B2 NUDT21 HNRNPUL1 U2AF2 SNRPD2P1 CSTF1 CSTF2 CSTF3 DHX9 HNRNPA3 DNAJC8 NCBP2 SNRNP200 SF3B3 SF3B1 PRPF6 FUS RBMX GTF2F1 GTF2F2 CPSF1 HNRNPA1 HNRNPA2B1 HNRNPC HNRNPD HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPL HNRNPU MAGOH HNRNPM NCBP1 NFX1 NHP2L1 YBX1 PCBP1 PCBP2 CDC40 PCF11 SF3B14 CPSF3 CPSF2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L CCAR1 PTBP1 SUGP1 LSM2 SRSF1 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 LOC643446 UPF3B LOC652147 LOC653889 SNRNP70 SNRPA SNRPA1 SNRPB SNRPB2 SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG U2AF1 CPSF7 PABPN1 SF3A2 SMC1A SF3B5 PHF5A SRSF9 PRPF4 SRSF11 EFTUD2 SNRNP40 DDX23 DHX38 RBM8A +REACTOME_MRNA_SPLICING_MINOR_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MRNA_SPLICING_MINOR_PATHWAY SF3B4 PRPF8 TXNL4A SF3B2 SNRPD2P1 NCBP2 SNRNP200 SF3B3 SF3B1 PRPF6 GTF2F1 GTF2F2 NCBP1 NHP2L1 SF3B14 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L LSM2 SRSF1 SRSF2 SRSF6 SRSF7 LOC652147 LOC653889 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SF3B5 EFTUD2 SNRNP40 DDX23 +REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION RPL35 RPL7AP27 EIF1AX EIF2S1 EIF2S3 EIF4A1 EIF4A2 EIF4B EIF4E EIF4G1 FAU RPL13A RPL36 PABPC1 EIF3K RPL10P16 FAM153A EIF3FP3 RPL36P14 EIF3E RPSAP12 RPS8P10 RPL7AP66 RPL10P9 RPS12P4 RPSA RPS26P10 RPL23AP2 RPS12P22 RPL21P29 RPS26P35 RPL10A RPL26L1 RPL3 RPL3L RPL4 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL10 RPL11 RPL12 RPL13 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL23A RPL24 RPL26 RPL27 RPL30 RPL27A RPL28 RPL29 RPL31 RPL32 RPL34 RPL35A RPL37 RPL37A RPL38 RPL39 RPL41 RPL36A RPLP0 RPLP1 RPLP2 RPS2 RPS3 RPS3A RPS4X RPS4Y1 RPS5 RPS6 RPS7 RPS8 RPS9 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS18 RPS19 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS28 RPS29 RPL6P19 LOC641895 RPL36AP31 RPS29P3 RPS26P28 RPL36AP8 RPL26P22 RPS26P20 RPS15AP11 RPS26P50 RPL22P11 RPL17P6 RPS13P8 RPS28P4 RPL32P16 LOC646184 RPS28P7 RPL12P2 LOC647074 RPL23AP42 RPL5P1 RPL36AP51 LOC649602 RPS28P9 RPL34P27 LOC651825 LOC651894 LOC652607 RPL26P30 RPSAP9 RPL19P9 RPL21P119 RPL31P17 LOC653881 LOC653994 RPL31P31 RPL15P17 RPL23AP18 RPL26P24 RPL21P75 RPS27AP11 RPS26P7 RPL21P134 RPS26P25 RPS19P3 RPL36AP23 RPS18P10 RPL17P36 RPL36AP37 RPL21P16 RPL23AP74 RPS15P5 RPL23AP63 RPS10P9 LOC730343 RPS18P5 UBA52 RPL34P31 EIF4H EIF3A EIF3B EIF3C EIF3D EIF3F EIF3G EIF3H EIF3I EIF3J EIF2S2 RPL14 RPL23 +REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA PAPOLA CLP1 NUDT21 LSM11 CSTF1 CSTF2 CSTF3 NCBP2 ZNF473 CPSF1 NCBP1 PCF11 CPSF3 CPSF2 SNRPB SNRPD3 SNRPE SNRPF SNRPG SLBP CPSF7 PABPN1 LSM10 +REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS PAICS ADSSL1 ADSL ADSS GART IMPDH1 IMPDH2 ATIC PFAS PPAT GMPS +REACTOME_G1_S_TRANSITION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G1_S_TRANSITION CDK2 PSMD14 CDK7 CDKN1A CDKN1B DBF4 CKS1B DHFR E2F1 ORC6 ORC3 POLA2 FBXO5 PPP2R3B RPA4 MAX MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MNAT1 LOC441488 MYC ORC1 ORC2 ORC4 ORC5 PCNA POLA1 POLE POLE2 PPP2CA PPP2CB PPP2R1A PPP2R1B MCM10 PRIM1 PRIM2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RB1 RPA1 RPA2 RPA3 RPS27A RRM2 DHFRP1 LOC645084 SKP1 SKP2 LOC652826 TFDP1 TK2 RPS27AP11 TYMS LOC729964 UBA52 WEE1 CDT1 CDC7 CDC45 MCM8 CUL1 CCNA2 CCNA1 CCNB1 CCNE1 CCNH PKMYT1 CCNE2 PSMF1 CDK1 PSMD6 CDC6 CDC25A +REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE CS DLD DLST FH NNT LOC283398 IDH2 IDH3A IDH3B IDH3G MDH2 OGDH ACO2 SDHA SDHB SDHC SDHD SUCLA2P1 LOC646675 LOC646677 LOC650667 LOC650674 LOC651820 SUCLG2 SUCLG1 SUCLA2 +REACTOME_TRANSCRIPTION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSCRIPTION THOC4 CDK7 CDK9 SRRM1 SNAPC5 POLR3F POLR3C PAPOLA EHMT2 RNPS1 CLP1 NUDT21 POLR3A LZTS1 SUPT16H CBX3 U2AF2 HIST4H4 HIST2H3C HIST3H2BB LSM11 CSTF1 CSTF2 CSTF3 POLR3H ERCC2 ERCC3 ERCC6 NCBP2 HIST1H2BA POLR1A ZNF473 COBRA1 PTRF GTF2A1 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 BRF1 GTF3C2 CPSF1 HIST1H2AE HIST1H2AD H2AFX H2AFZ HIST1H2BD HIST1H2BB H3F3A H3F3B HIST2H3A H3F3AP5 MAGOH MNAT1 NCBP1 NFIB NFX1 POLR1D CDC40 TH1L PCF11 CPSF3 POLR3K CPSF2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L POLRMT POU2F1 RRN3 BRF2 HIST2H4B POLR3B POLR3E MAPK3 TFB2M SRSF1 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 LOC643446 TCEB1P3 H3F3AP6 UPF3B LOC652857 GTF2H2B HIST2H3D LOC653972 POLR3D SNAPC1 SNAPC2 SNAPC3 SNAPC4 SNRPB SNRPD3 SNRPE SNRPF SNRPG SSB SSRP1 SUPT4H1 SUPT5H TAF1 TAF4 TAF4B TAF5 TAF6 TAF9 TAF10 TAF11 TAF12 TAF13 TBP TCEA1 TCEB1 TCEB2 TCEB3 TFAM HIST2H2AA4 U2AF1 LOC731820 UBTF WHSC2 ZNF143 SLBP RDBP MTERF CPSF7 PABPN1 ELL HIST1H4I HIST1H2AJ HIST1H2AC HIST1H2AB HIST2H2AA3 HIST2H2AC HIST1H2BG HIST1H2BL HIST1H2BN HIST1H2BM HIST1H2BF HIST1H2BE HIST1H2BH HIST1H2BI HIST1H2BC HIST1H2BO HIST2H2BE HIST1H3A HIST1H3D HIST1H3C HIST1H3E HIST1H3I HIST1H3G HIST1H3J HIST1H3H HIST1H3B HIST1H4A HIST1H4D HIST1H4F HIST1H4K HIST1H4J HIST1H4C HIST1H4H HIST1H4B HIST1H4E HIST1H4L HIST2H4A POLR1B POLR3GL LSM10 HIST1H2BK SRSF9 RNMT RNGTT KAT2B MBD2 HIST1H3F HIST1H2BJ TAF1C TAF1B TAF1A CCNH CCNT1 CCNT2 CTDP1 SRSF11 GTF3C5 GTF3C4 GTF3C3 POLR1C DHX38 RBM8A +REACTOME_POL_SWITCHING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_POL_SWITCHING POLD3 POLA2 PCNA POLA1 POLD1 POLD2 PRIM1 PRIM2 POLD4 RFC2 RFC3 RFC4 RFC5 +REACTOME_NUCLEOTIDE_EXCISION_REPAIR http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NUCLEOTIDE_EXCISION_REPAIR CDK7 POLD3 ERCC8 DDB1 DDB2 ERCC1 ERCC2 ERCC3 ERCC4 ERCC5 ERCC6 GTF2H1 GTF2H2 GTF2H3 GTF2H4 LIG1 MNAT1 PCNA POLD1 POLD2 POLE POLE2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L XAB2 POLD4 RAD23B RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 LOC652672 LOC652857 GTF2H2B TCEA1 XPA XPC CCNH +REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY FANCD2 ZBTB32 ATM ATR RPS27A LOC648152 LOC651610 LOC651921 RPS27AP11 UBA52 USP1 +REACTOME_AXON_GUIDANCE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AXON_GUIDANCE RANBP9 PLXNC1 CDK5 PAK4 SEMA3A MYL12B MYL9 CAP2 CAP1 SEMA4D DPYSL4 CFL1 STIP1 AP2M1 AP2S1 CLTA CLTC CNTN1 COL1A1 COL1A2 COL2A1 COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL5A1 COL5A2 COL6A1 COL6A2 COL6A3 COL9A1 COL9A2 COL9A3 UNC5D CREB1 CRMP1 CSNK2A1 CSNK2A2 CSNK2B NCAN HFE2 AP2A1 AP2A2 AP2B1 DCC DCX DLG1 DLG3 DNM1 DNM2 DOCK1 DPYSL2 DPYSL3 EGFR ERBB2 ALCAM UNC5B FES FGFR1 ABLIM3 PLXND1 CLASP1 ARHGEF12 SRGAP2 PIP5K1C KIF4A ABL1 FYN GDNF GFRA1 GFRA2 ABL2 CNTN6 RND1 RPS6KA6 GPC1 LAMA1 KIF4B RGMB ANK1 ANK3 GRB2 ARHGAP35 HRAS HSP90AA1 HSP90AB1 ITGA1 ITGA2 ITGA2B ITGA5 ITGA9 ITGAV ITGB1 ITGB3 AGRN KCNQ2 KCNQ3 KRAS RHOA RHOB RHOC L1CAM RHOG LAMB1 LAMC1 ABLIM1 LIMK1 LIMK2 MET MSN MYH9 MYH10 MYH11 MYL6 MYO10 NCAM1 NCK1 NEO1 NRAS NRCAM NRTN PAK1 PAK2 SPTBN5 EVL PFN1 PFN2 PITPNA PLCG1 PLXNA1 PLXNA2 PLXNB1 PLXNB3 TREM2 PLXNA3 ENAH SCN3B PRKCQ MAPK1 MAPK3 MAP2K1 MAP2K2 PRNP PSPN DPYSL5 PAK6 RGMA TRPC7 PAK7 PTK2 SRGAP1 SEMA6A KIAA1598 SPTBN4 PTPRC RAC1 RAC2 RAF1 NTN4 RDX ROBO1 ROBO2 ROCK1 RPS6KA1 RPS6KA2 RPS6KA3 RRAS SCN1B SCN2A SCN2B SCN4A SCN5A SCN7A SCN8A SDCBP GFRA4 MYL8P LOC642076 SEMA4A ROBO3 LOC644816 SH3GL2 SIAH1 SIAH2 LOC650400 SLIT1 SLIT3 SOS1 SOS2 SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SRC CNTN2 TLN1 TRIO TRPC3 TRPC4 TRPC5 TRPC6 ROCK1P1 LOC729030 LOC730030 LOC730221 LOC730335 TYROBP LOC731231 VASP EZR YWHAB CACNA1S CACNB1 CACNB2 CACNB3 CACNB4 ST8SIA4 MYH14 SEMA6D ST8SIA2 NCK2 SEMA7A CNTNAP1 UNC5C NUMB NRP2 NRP1 CDK5R1 CACNA1I CACNA1H CACNA1G WASL RPS6KA4 UNC5A SEMA5A ARTN RPS6KA5 CD24 SLIT2 NTN1 ROCK2 CD72 SEMA3E ARHGEF11 CDK1 FARP2 SRGAP3 CDC42 +REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S CTDSP2 PREB PDIA6 HYOU1 YIF1A PDIA5 KDELR3 KLHDC3 ADD1 TPP1 DCTN1 DDX11 EXTL3 SEC31A SERP1 GSK3A HDGF CXXC1 ACADVL LMNA DNAJB9 DDX12P SULT1A4 DNAJB11 FKBP14 WIPI1 PPP2R5B ARFGAP1 C19orf10 DNAJC3 SRPRB TSPYL2 SHC1 SRPR SSR1 SULT1A3 TLN1 WFS1 XBP1 ZBTB17 SYVN1 ATP6V0D1 GOSR2 EDEM1 TATDN2 CUL7 +REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 RAPGEF3 GNB5 RAPGEF4 ADCY5 ADCY6 ADCY8 KCNG2 GCG GLP1R GNAS GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 ITPR2 ITPR3 KCNB1 KCNC2 KCNS3 GNG13 GNG2 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B GNG12 RAP1A RAP1B GNB4 LOC730418 IQGAP1 GNG8 AKAP5 +REACTOME_PERK_REGULATED_GENE_EXPRESSION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PERK_REGULATED_GENE_EXPRESSION EXOSC8 EXOSC6 DDIT3 DCP2 EIF2S1 DIS3 ATF6 EXOSC7 EXOSC2 HSPA5 IGFBP1 IL8 ASNS ATF3 ATF4 NFYA NFYB PARN EXOSC3 EXOSC1 EXOSC9 EXOSC4 EXOSC5 CCL2 ATF4P3 LOC730136 KHSRP EIF2AK3 HERPUD1 +REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS RASGRP1 LPAR6 RASGRP2 RGS19 NMUR1 GNB5 CYSLTR1 NMU NPFFR2 PROKR1 UTS2 CHRM1 CHRM3 CHRM5 MGLL ARHGEF25 LTB4R PROKR2 NMS DGKK ADRA1D ADRA1B ADRA1A ADRBK1 DGKA DGKB DGKG DGKH DGKQ AGT AGTR1 LPAR1 EDN1 EDN2 EDN3 EDNRA EDNRB F2 F2R F2RL1 F2RL2 DAGLB GPRC6A PLCB1 LPAR3 FPR2 NTSR2 GAST UTS2D GCG GCGR GHSR P2RY10 GNA11 GNA15 GNAQ GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GNRH1 GNRH2 GNRHR GPR4 XCR1 UTS2R GPR17 LPAR4 MCHR1 MLNR FFAR1 FFAR3 FFAR2 GRK5 GRP GRPR GPR132 ANXA1 HCRT HCRTR1 HCRTR2 HRH1 HTR2A HTR2B HTR2C QRFP APP ITPR2 ITPR3 KISS1 KNG1 NPSR1 MLN RGS21 NMB NMBR NTS NTSR1 OXT OXTR P2RY1 P2RY2 P2RY6 P2RY11 GHRL GNG13 PIK3CA PIK3R1 PIK3R2 PLCB2 PLCB3 PLCB4 PMCH GNG2 AVP AVPR1A AVPR1B PRKCD PRKCE PRKCH PRKCQ GNG12 LTB4R2 NMUR2 CYSLTR2 TRPC7 PTAFR PTGER1 PTGFR GNB4 NPS RGS2 BDKRB1 BDKRB2 SAA1 XCL1 NPFFR1 RGS18 BRS3 XCL2 TAC1 TACR2 TAC3 TACR1 TACR3 TBXA2R TRH TRHR TRIO TRPC3 TRPC6 LOC730221 LOC730335 LOC730413 LOC731823 DAGLA GPR68 QRFPR PROK1 MCHR2 CASR KISS1R GPR65 PIK3R3 DGKE DGKD NPFF CCK CCKAR CCKBR KALRN F2RL3 DGKI LPAR2 OPN4 GNG8 GNA14 +REACTOME_P2Y_RECEPTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_P2Y_RECEPTORS LPAR6 P2RY10 GPR17 LPAR4 P2RY1 P2RY2 P2RY4 P2RY6 P2RY11 P2RY13 P2RY12 P2RY14 +REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS CACNG3 CACNG2 AP2M1 AP2S1 AP2A1 AP2A2 AP2B1 DLG1 EPB41L1 CACNG4 GRIA1 GRIA2 GRIA3 GRIA4 MDM2 MYO6 NSF PRKCA PRKCB PRKCG CACNG8 LOC651907 GRIP2 CAMK2A CAMK2B CAMK2D PICK1 AKAP5 +REACTOME_NCAM1_INTERACTIONS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NCAM1_INTERACTIONS COL1A1 COL1A2 COL2A1 COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL5A1 COL5A2 COL6A1 COL6A2 COL6A3 COL9A1 COL9A2 COL9A3 NCAN GDNF GFRA1 GFRA2 AGRN NCAM1 NRTN PRNP PSPN GFRA4 CNTN2 CACNA1S CACNB1 CACNB2 CACNB3 CACNB4 ST8SIA4 ST8SIA2 CACNA1I CACNA1H CACNA1G ARTN +REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS GPRC6A GABBR1 GRM1 GRM2 GRM3 GRM4 GRM6 GRM7 GRM8 LOC652292 TAS1R2 TAS1R1 TAS1R3 CASR GABBR2 +REACTOME_REGULATION_OF_INSULIN_SECRETION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_INSULIN_SECRETION RAPGEF3 CDX2 GNB5 RAPGEF4 ADCY5 ADCY6 CHRM3 ADCY8 GPR119 CTNNB1 ADRA2A DPP4 PLCB1 SEC11A KCNG2 GATA4 GCG GIP GLP1R GNA11 GNA15 GNAI1 GNAI2 GNAO1 GNAQ GNAS GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 FFAR1 SPCS1 SLC25A4 SLC25A5 GRP SLC25A6 O3FAR1 INS ISL1 ITPR2 ITPR3 KCNB1 KCNC2 KCNJ11 KCNS3 LEP MARCKS PAX6 PCSK1 GNG13 PLCB2 PLCB3 GNG2 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA GNG12 RAP1A RAP1B GNB4 SPCS3 SLC2A1 SLC2A2 LOC653566 SNAP25 STX1A STXBP1 ABCC8 VAMP2 SYT5 LOC730413 LOC730418 CACNA1A CACNB2 CACNB3 IQGAP1 SEC11C GNG8 AKAP5 GNA14 SPCS2 +REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH COL1A1 COL1A2 COL2A1 COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL5A1 COL5A2 COL6A1 COL6A2 COL6A3 COL9A1 COL9A2 COL9A3 CREB1 NCAN FGFR1 FYN GDNF GFRA1 GFRA2 GRB2 HRAS AGRN KRAS NCAM1 NRAS NRTN SPTBN5 MAPK1 MAPK3 MAP2K1 MAP2K2 PRNP PSPN PTK2 SPTBN4 RAF1 GFRA4 SOS1 SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SRC CNTN2 YWHAB CACNA1S CACNB1 CACNB2 CACNB3 CACNB4 ST8SIA4 ST8SIA2 CACNA1I CACNA1H CACNA1G ARTN RPS6KA5 CDK1 +REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE GNB5 ADCY5 ADCY6 ADRA2A GNAI1 GNAI2 GNAO1 GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GNG13 GNG2 GNG12 GNB4 CACNB2 CACNB3 GNG8 +REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS LPAR6 ADORA1 ADORA2A ADORA2B ADORA3 P2RY10 GPR17 LPAR4 P2RY1 P2RY2 P2RY4 P2RY6 P2RY11 P2RY13 P2RY12 P2RY14 +REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA DDIT3 ATF6 HSPA5 ATF4 NFYA NFYB MBTPS2 ATF4P3 HSP90B1 LOC730136 XBP1 CALR MBTPS1 +REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT THOC4 NXF1 NUP50 NUPL2 NUP35 EIF4E NCBP2 NUP205 NUP210 NUP188 NUP62 CPSF1 NUP43 NCBP1 NUP88 CPSF3 NUP54 CPSF2 NUP133 NUP107 RANBP2 TPR NUP37 NUP85 NUP214 AAAS SEH1L RAE1 NUP155 NUP93 NUPL1 POM121 NUP153 +REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS CYSLTR1 GPR44 LTB4R OXER1 GPR17 LTB4R2 CYSLTR2 PTGDR PTGER1 PTGER2 PTGER3 PTGER4 PTGFR PTGIR TBXA2R LOC730002 +REACTOME_ACTIVATION_OF_GENES_BY_ATF4 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_GENES_BY_ATF4 EXOSC8 EXOSC6 DDIT3 DCP2 DIS3 ATF6 EXOSC7 EXOSC2 IGFBP1 IL8 ASNS ATF3 ATF4 NFYA NFYB PARN EXOSC3 EXOSC1 EXOSC9 EXOSC4 EXOSC5 CCL2 ATF4P3 LOC730136 KHSRP HERPUD1 +REACTOME_UNFOLDED_PROTEIN_RESPONSE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_UNFOLDED_PROTEIN_RESPONSE CTDSP2 PREB PDIA6 HYOU1 YIF1A PDIA5 KDELR3 EXOSC8 KLHDC3 ADD1 EXOSC6 TPP1 DCTN1 DDIT3 DDX11 DCP2 EIF2S1 ERN1 EXTL3 SEC31A DIS3 ATF6 EXOSC7 EXOSC2 SERP1 GSK3A HDGF CXXC1 HSPA5 IGFBP1 IL8 ACADVL LMNA DNAJB9 ASNS DDX12P SULT1A4 ATF3 ATF4 NFYA NFYB PARN EXOSC3 EXOSC1 MBTPS2 DNAJB11 EXOSC9 EXOSC4 FKBP14 WIPI1 PPP2R5B ARFGAP1 C19orf10 DNAJC3 EXOSC5 SRPRB CCL2 TSPYL2 ATF4P3 SHC1 SRPR SSR1 SULT1A3 TLN1 HSP90B1 LOC730136 WFS1 XBP1 ZBTB17 CALR SYVN1 KHSRP MBTPS1 ATP6V0D1 EIF2AK3 GOSR2 EDEM1 HERPUD1 TATDN2 CUL7 +REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS CALCRL RAMP2 RAMP1 RAMP3 GNB5 FZD10 PTH2 ADCYAP1 ADCYAP1R1 ADM CRH CRHR2 CD55 EMR1 FZD2 GCG GCGR GHRH GHRHR GIP GIPR GLP1R GNAS GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 EMR2 IAPP IHH DHH WNT16 GNG13 GNG2 WNT4 GNG12 PTCH1 PTH PTHLH PTH1R PTH2R GNB4 SCT SCTR SHH LOC649279 SMO VIP VIPR1 VIPR2 WNT1 WNT2 WNT3 WNT5A WNT6 WNT7A WNT7B WNT8B WNT10B WNT11 WNT2B WNT9A WNT9B FZD5 CALCA CALCB FZD3 ADM2 WNT10A FZD1 FZD4 FZD6 FZD7 FZD8 FZD9 EMR3 PTCH2 WNT3A GLP2R GNG8 CD97 +REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS GNB5 ADCYAP1 ADCYAP1R1 GCG GCGR GHRH GHRHR GIP GIPR GLP1R GNAS GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GNG13 GNG2 GNG12 GNB4 SCT SCTR VIP VIPR1 VIPR2 GLP2R GNG8 +REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE CHRM3 PLCB1 GNA11 GNA15 GNAQ MARCKS PLCB2 PLCB3 PRKCA LOC730413 GNA14 +REACTOME_G_ALPHA1213_SIGNALLING_EVENTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G_ALPHA1213_SIGNALLING_EVENTS NET1 VAV3 GNA13 GNB5 AKAP13 FGD4 ADRA1D ADRA1B ADRA1A ECT2 FGD2 FGD1 ARHGEF9 ARHGEF12 ARHGEF18 NGEF TIAM2 ARHGEF16 GNA12 GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 ABR RHOA RHOB RHOC RHOG ARHGAP4 MCF2 ARHGEF4 ARHGEF3 GNG13 PIK3CA PIK3R1 PIK3R2 PLXNB1 GNG2 GNG12 PREX1 RAC1 RAC2 RASGRF1 RASGRF2 GNB4 ROCK1 ITSN1 PLEKHG2 SOS1 SOS2 TBXA2R TIAM1 TRIO ROCK1P1 VAV1 OBSCN PIK3R3 FGD3 KALRN ARHGEF1 ARHGEF2 GNG8 ARHGEF6 ROCK2 ARHGEF11 ARHGEF17 CDC42 +REACTOME_FANCONI_ANEMIA_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FANCONI_ANEMIA_PATHWAY FANCA FANCC FANCD2 FANCE FANCB FANCF FANCG ZBTB32 UBE2T ATM ATR FANCL FANCM RPS27A LOC648152 LOC651610 LOC651921 BRCA1 BRCA2 RPS27AP11 UBA52 USP1 PALB2 C17orf70 C19orf40 +REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS AP2M1 AP2S1 AP2A1 AP2A2 AP2B1 GRIA1 GRIA2 GRIA3 GRIA4 NSF PRKCA PRKCB PRKCG LOC651907 GRIP2 PICK1 +REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA DDIT3 ATF6 HSPA5 ATF4 NFYA NFYB ATF4P3 HSP90B1 LOC730136 XBP1 CALR +REACTOME_PROSTANOID_LIGAND_RECEPTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROSTANOID_LIGAND_RECEPTORS GPR44 PTGDR PTGER1 PTGER2 PTGER3 PTGER4 PTGFR PTGIR TBXA2R LOC730002 +REACTOME_OPSINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_OPSINS RRH OPN5 OPN3 OPN1MW OPN1LW RGR RHO OPN1SW OPN1MW2 OPN4 +REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ CDK7 CDK9 SUPT16H ERCC2 ERCC3 NCBP2 COBRA1 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 MNAT1 NCBP1 TH1L POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L TCEB1P3 LOC652857 GTF2H2B SSRP1 SUPT4H1 SUPT5H TCEA1 TCEB1 TCEB2 TCEB3 WHSC2 RDBP ELL CCNH CCNT1 CCNT2 CTDP1 +REACTOME_MRNA_3_END_PROCESSING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MRNA_3_END_PROCESSING THOC4 SRRM1 PAPOLA RNPS1 CLP1 NUDT21 U2AF2 CSTF1 CSTF2 CSTF3 NCBP2 CPSF1 MAGOH NCBP1 NFX1 CDC40 PCF11 CPSF3 CPSF2 SRSF1 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 LOC643446 UPF3B U2AF1 CPSF7 PABPN1 SRSF9 SRSF11 DHX38 RBM8A +REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS PIGK PIGU PIGN PIGW PIGP PIGT PIGA PIGC PIGF PIGH PLAUR DPM3 PIGG PIGX PIGV SEMA6D PGAP1 PIGO GPAA1 DPM1 DPM2 PIGQ PIGM PIGS PIGL PIGB +REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION CDK7 MNAT1 PLK1 WEE1 XPO1 CCNA2 CCNA1 CCNB1 CCNH PKMYT1 CCNB2 CDK1 CDC25A CDC25B CDC25C +REACTOME_ELONGATION_ARREST_AND_RECOVERY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ELONGATION_ARREST_AND_RECOVERY CDK9 SUPT16H COBRA1 GTF2F1 GTF2F2 TH1L POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L TCEB1P3 SSRP1 SUPT4H1 SUPT5H TCEA1 TCEB1 TCEB2 TCEB3 WHSC2 RDBP ELL CCNT1 CCNT2 CTDP1 +REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT SLC9A6 SLC35A1 SLC34A2 SLCO1B1 SLC12A7 NUP50 SLC26A1 SLC22A7 SLC38A3 SLC27A4 SLC35D2 NUPL2 SLC7A9 SLC2A6 SLC6A14 SLCO2B1 SLC2A13 SLC26A9 SLC26A7 SLC5A11 SLC22A12 SLC16A10 SLC15A4 SLC24A4 SLC43A2 SLC44A3 NUP35 SLC31A1 CP SLC32A1 SLC34A3 SLC25A10 SLC47A2 SLC30A7 SLC36A2 SLC2A12 SLC2A7 SLC5A8 SLC30A8 SLC26A3 SLC26A2 SLC29A1 SLC44A5 SLC36A1 ALB SLC29A4 NUP205 SLC35D1 NUP210 SLC9A8 SLC7A8 SLC35A3 SLC44A1 NUP188 SLC16A8 NUP62 SLC7A11 SLC17A8 G6PC SLC37A4 SLC41A1 SLC24A2 SLC39A6 GCK GCKR SLC17A5 SLC39A1 SLCO4A1 SLCO3A1 SLCO1B3 SLC39A5 SLC24A5 SLC13A5 SLC9A9 SLC27A6 SLC39A3 SLC39A2 SLC2A8 SLC40A1 HK1 HK2 HK3 SLC29A2 SLC6A19 SLC10A6 SLC35B2 SLC6A18 NUP43 SLCO4C1 SLC27A1 SLC9A4 NUP88 SLC22A18 SLC15A3 RHCG SLC26A4 NUP54 SLCO1C1 SLC38A2 SLC6A20 SLC38A4 AVP SLC6A15 SLC47A1 SLC29A3 SLC35C1 SLC22A15 SLC39A4 NUP133 SLC22A11 SLC7A10 SLC2A9 SLC17A7 SLC17A6 NUP107 SLC44A2 SLC39A10 SLC24A3 SLC12A5 G6PC2 SLC4A5 RANBP2 RHAG SLC5A7 SLC28A3 SLC39A8 SLC13A3 SLC30A5 SLC26A6 SLC1A1 SLC1A2 SLC1A3 SLC4A3 SLC1A4 SLC1A5 SLC1A6 SLC1A7 SLC2A1 SLC2A2 SLC2A3 SLC2A4 SLC2A5 SLC3A1 SLC3A2 SLC4A1 SLC4A2 SLC5A1 SLC5A2 SLC5A3 LOC652661 SLC5A5 SLC6A1 SLC6A2 SLC6A3 SLC6A6 SLC6A7 SLC6A9 SLC6A11 SLC6A12 SLC7A1 SLC7A2 SLC8A2 SLC8A1 SLC8A3 SLC9A1 SLC9A2 SLC9A3 SLC9A5 SLC11A1 SLC12A1 SLC12A2 SLC12A4 SLC13A1 SLC14A1 SLC15A1 SLC15A2 SLC16A1 SLC17A1 SLC34A1 SLC18A1 SLC18A2 SLC20A1 SLC20A2 SLCO2A1 SLCO1A2 SLC22A1 SLC22A3 SLC22A2 SLC22A4 SLC22A5 SLC2A11 TPR SLC35A2 SLC30A1 SLC30A2 SLC30A3 NUP37 SLC39A7 NUP85 SLC24A6 NUP214 SLC44A4 AAAS SLC2A10 SLC7A5 SLC38A1 SLC14A2 SEH1L SLC4A9 SLC41A2 SLC9A7 RAE1 SLC7A3 SLC35B4 SLC43A1 SLC22A16 SLC4A4 SLC5A6 SLC7A7 SLC7A6 SLC13A2 SLC16A3 SLC6A5 SLC28A2 SLC28A1 SLC24A1 SLC16A7 SLC33A1 G6PC3 SLC38A5 SLC22A6 SLC22A8 SLC4A7 SLC4A8 NUP155 NUP93 NUPL1 HEPH POM121 NUP153 SLC12A6 +REACTOME_ADP_SIGNALLING_THROUGH_P2RY1 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ADP_SIGNALLING_THROUGH_P2RY1 GNB5 MAPK14 GNA11 GNA15 GNAQ GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 P2RY1 GNG13 PLA2G4A GNG2 GNG12 GNB4 SRC GNG8 GNA14 +REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA GNB5 PLCB1 GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GNG13 PLCB2 PLCB3 GNG2 GNG12 GNB4 GNG8 +REACTOME_CD28_CO_STIMULATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CD28_CO_STIMULATION AKT3 THEM4 MAP3K8 AKT1 AKT2 MTOR RICTOR FYN GRB2 LCK LYN PAK1 PAK2 PDPK1 PIK3CA PIK3R1 PIK3R2 TRIB3 RAC1 MLST8 SRC LOC729120 VAV1 YES1 MAPKAP1 PIK3R3 MAP3K14 CD28 GRAP2 CD80 CD86 CDC42 +REACTOME_GPCR_DOWNSTREAM_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GPCR_DOWNSTREAM_SIGNALING AKT3 INSL5 RASGRP1 LPAR6 CALCRL RASGRP2 RAMP2 RAMP1 RAMP3 NET1 RGS19 NMUR1 VAV3 CXCL13 CXCR6 GNA13 GNB5 RRH ADCY1 OR5I1 ADCY2 CYSLTR1 CCR9 CGA PDE10A CCL27 NMU NPFFR2 PROKR1 ADCY3 UTS2 ADCY5 ADCY6 AKAP13 GPR44 HRH3 CHRM1 CHRM2 ADCY7 PTH2 CHRM3 CHRM5 MGLL ADCY8 ADCY9 ARHGEF25 ADCYAP1 ADCYAP1R1 RLN3 OR52E2 OR52J3 OR51L1 OR51A7 OR51S1 OR51F2 OR52R1 OR4X2 OR4B1 OR52M1 OR52K2 OR5P2 OR5P3 OR8I2 OR2D3 OR2D2 OR52W1 OR56A4 OR56A1 OR10P1 OR10AD1 OR10A7 FGD4 RXFP2 OR4K14 OR4L1 CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 LTB4R OR4D2 OR7D4 OR7G1 OR1M1 OR1I1 OR10H4 CNR1 CNR2 OR2M5 OR2M3 OR2T12 OR14C36 OR2T34 OR2T10 OR2T4 OR2T11 OR10J5 OR2B11 OR10T2 OR10X1 OR10Z1 OR6K6 OR6N1 PROKR2 NMS OR9A4 ADM ADORA1 OR2Y1 TAAR1 ADORA2A OR9A2 OR2A14 OR6B1 OR2F2 ADORA2B OR1L8 OR1N2 OR1N1 DGKK CRH CRHR2 ADORA3 OR52B4 OR52I2 OR51E1 OR10A5 OR2AG1 ADRA1D PIK3R6 ADRA1B ADRA1A ADRA2A OR6B3 ADRA2B GPBAR1 ADRB1 ADRB2 ADRB3 ADRBK1 OR1Q1 DGKA DGKB DGKG DGKH DGKQ OR7D2 OXER1 DRD1 DRD2 DRD3 DRD5 AGT AGTR1 AGTR2 APLNR ECT2 S1PR1 LPAR1 S1PR3 EDN1 EDN2 EDN3 EDNRA EDNRB OR56B4 ADCY4 AKT1 AKT2 F2 F2R F2RL1 F2RL2 OR8U1 OR4C16 OR4C11 OR4S2 OR4C6 OR5D14 OR5L1 OR5D18 OR5AS1 OR8K5 OR5T2 OR8H1 OR8K3 OR8J1 OR5R1 OR5M3 OR5M8 OR5AR1 OR8B12 OR10G8 OR10G9 OR10S1 OR6T1 OR4D5 OR6Q1 OR9I1 OR9Q1 OR9Q2 OR1S2 OR1S1 OR10Q1 OR5B17 OR5A2 OR5A1 OR4D6 OR4D11 OPN5 FGD2 DAGLB GPRC6A FGD1 ARHGEF9 PLCB1 ARHGEF12 ARHGEF18 PIK3R5 OR52A1 LPAR3 FPR1 FPR2 FPR3 OPN3 NTSR2 FSHB FSHR GAST OR6C3 OR1L4 GABBR1 OR4C3 OR4S1 NPB UTS2D NGEF GALR1 OR1C1 OR1A2 OR2F1 OR2B6 OR1J4 TIAM2 OR2M4 OR2L2 OR2K2 OR7A17 OR5L2 OR5K1 GCG GCGR OR10J1 OR8B8 OR10A3 OPN1MW OR11A1 OR10H3 OR10G3 OR10G2 OR10H2 OR10H1 RGS17 OR7C2 OR7A5 OR7C1 OR4F4 OR4F3 OR4E2 OR4D1 OR2W1 OR2T1 OR2H1 OR1L3 OR1L1 OR1J2 GHRH GHRHR GHSR GIP GIPR PDE7B ARHGEF16 P2RY10 GLP1R GNA11 GNA12 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAQ GNAS GNAT1 GNAT2 GNAZ GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GNRH1 GNRH2 GNRHR CCR10 OR51B5 OR10AG1 OR5J2 GPR4 XCR1 OR4C13 OR4C12 NPBWR1 OR51V1 OR8D1 OR8D2 OR8B4 OR9G4 NPBWR2 OR10A4 CXCR3 OR4N4 UTS2R NPW GPR17 GPR18 OR2Z1 OR10H5 OR2L13 OR14A16 LPAR4 MCHR1 GPER OR2V2 MLNR FFAR1 FFAR3 FFAR2 GRK5 ABR CXCL1 CXCL2 CXCL3 GRP GRPR GPR132 ANXA1 HCRT HCRTR1 HCRTR2 TAAR6 HRH1 HRH2 HTR1A HTR1B HTR1D HTR1E HTR1F HTR2A HTR2B HTR2C HTR4 HTR5A HTR6 HTR7 IAPP HCAR2 OR8D4 OR5F1 OR5AP2 OR52L1 RXFP4 OR52B6 OR10A2 OR6C2 OR6C4 OR8S1 OR6S1 OR6F1 OR14K1 OR2W3 OR2T3 OR10R2 OR2T29 OR6V1 OR2A12 OR2A1 QRFP OR1J1 OR1B1 APP IL8 CXCR1 CXCR2 CXCL10 INSL3 ITPR2 ITPR3 KISS1 KNG1 RHOA NPSR1 OR56B1 RHOB RHOC OR6B2 OR52K1 OR52I1 OR51D1 OR52A5 OR51B6 OR51M1 OR51Q1 OR51I1 OR51I2 OR52D1 OR52H1 OR52N4 OR52N5 OR52N2 OR52E6 OR52E8 OR52E4 OR56A3 OR10A6 OR4X1 OR5D13 OR5D16 OR5W2 OR8H2 OR8H3 OR5T3 OR5T1 OR8K1 OR5M9 OR9G1 OR5AK2 OR5B2 OR5B12 OR5AN1 OR4D9 OR10V1 OR6X1 OR6M1 OR10G4 OR10G7 OR8B3 OR8A1 OR6C1 OR4N2 OR4K2 OR4K13 OR4K17 OR4N5 OR11G2 OR5AU1 OR4M2 OR4F6 OR4F15 OR3A4P OR7G2 OR7G3 OR7A10 RHOG OR10K2 OR10K1 OR6Y1 OR6K3 OR2L8 OR2AK2 OR2L3 OR2M2 OR2T33 OR2M7 OR2G6 OR2A25 OR1L6 OR5C1 OR1K1 ARHGAP4 OR2A5 LHB LHCGR OR2A7 OR51T1 OR51A4 OR51A2 OR2T2 OR2T5 OR5K2 OR2A42 OR2T27 OR2T35 OR4A47 MC1R MC2R MC3R MC4R MC5R MCF2 CXCL9 MLN RGS21 OR5B3 OR9K2 OR4Q3 OR4M1 OR10J3 OR2B3 OR2J3 OR14J1 OR10C1 OR2A2 MTNR1A MTNR1B NMB NMBR NPY NPY1R NPY2R NPY5R NTS NTSR1 OPRD1 OPRK1 OPRL1 OPRM1 OR1D2 OR1F1 OR2C1 OR3A1 OR3A2 OXT OXTR P2RY1 P2RY2 P2RY4 P2RY6 P2RY11 OR8U8 OR8U9 OR9G9 ARHGEF4 ARHGEF3 HEBP1 PDE11A GAL RXFP3 PDE1A PDE2A PDE3A PDE3B PDE4B PDE4C PDE4D PDE7A PDE8A PDE1B PDPK1 PDYN GHRL GNG13 PENK PF4 PIK3CA PIK3CG PIK3R1 PIK3R2 PLCB2 PLCB3 PLCB4 S1PR5 PLXNB1 PMCH PNOC P2RY13 GNG2 POMC PPBP AVP AVPR1A AVPR1B PPY AVPR2 PPYR1 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCQ GNG12 LTB4R2 CCL28 OR2S2 NMUR2 PYY CXCR7 CYSLTR2 TRPC7 PTAFR PTGDR PTGER1 PTGER2 PTGER3 PTGER4 PTGFR PTGIR PTH PTHLH PTH1R PTH2R PREX1 CXCL16 RAC1 RAC2 RASGRF1 RASGRF2 HRH4 GNB4 RXFP1 NPS OPN1LW RGR RGS1 RGS2 RGS4 RGS7 RGS12 RHO RLN2 ROCK1 OPN1SW BDKRB1 BDKRB2 SAA1 SCT SCTR CCL5 CCL16 CCL19 CCL20 CCL21 CCL25 CXCL6 CXCL11 CXCL5 XCL1 CXCL12 NPFFR1 CXCR5 RGS18 ITSN1 P2RY12 PLEKHG2 OR4N3P LOC652222 LOC652692 LOC653879 SOS1 SOS2 SST SSTR1 SSTR2 SSTR3 SSTR4 SSTR5 BRS3 XCL2 TAC1 TACR2 TAC3 TACR1 TACR3 TBXA2R TIAM1 C3 C3AR1 TRH TRHR TRIO TRPC3 TRPC6 TSHB TSHR C5 ROCK1P1 C5AR1 OPN1MW2 OR4F29 LOC730002 LOC730221 LOC730335 LOC730413 LOC730421 LOC730808 LOC731823 VAV1 VIP VIPR1 VIPR2 DAGLA CXCR4 OR5H6 OR5H2 OR4K5 OR51G1 OR51B4 OR51B2 OR52N1 OR4F5 OR2A4 OR4K1 CALCA CALCB ADM2 OR5AC2 OR4F17 GPR68 OR4K15 OR8J3 OR51G2 OR51E2 OR4P4 OR4C15 OR4A5 OR4A16 OR4A15 OR10W1 OR2AE1 OR4F16 OR6N2 OR6K2 OR2G3 OR2G2 OR2C3 OR5V1 OR2B2 TAAR8 OR1A1 OR1D4 OR1D5 OR1E1 OR1E2 OR1G1 OR3A3 OBSCN QRFPR PROK1 MCHR2 CASR KISS1R GPR65 GALR3 PIK3R3 DGKE DGKD RGS8 OR6A2 RGS20 NPFF PDE8B S1PR4 RGS11 RGS9 GALR2 HCAR3 CCK CCKAR CCKBR FGD3 KALRN F2RL3 TAAR5 ARHGEF1 DGKI LPAR2 ARHGEF2 TAAR2 GPR55 S1PR2 GLP2R OPN4 GNG8 ARHGEF6 ROCK2 GABBR2 RGS6 GNA14 ARHGEF11 ARHGEF17 P2RY14 CDC42 +REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN SEC11A GCG GH1 SPCS1 INS LEP PCSK1 GHRL BCHE SPCS3 MBOAT4 LOC653566 PLA2G7 SEC11C KLF4 SPCS2 +REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS CDH2 CDH3 CDH4 CDH5 CDH6 CDH7 CDH8 CDH9 CDH10 CDH11 CDH12 CDH13 CDH15 CDH18 CTNNA1 CTNNB1 CTNND1 CADM1 CADM2 PVRL3 JUP PVR PVRL1 PVRL2 CDH24 PVRL4 CDH1 +REACTOME_CRMPS_IN_SEMA3A_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CRMPS_IN_SEMA3A_SIGNALING CDK5 SEMA3A DPYSL4 CRMP1 DPYSL2 DPYSL3 FES FYN PLXNA1 PLXNA2 PLXNA3 DPYSL5 NRP1 CDK5R1 +REACTOME_OTHER_SEMAPHORIN_INTERACTIONS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_OTHER_SEMAPHORIN_INTERACTIONS PLXNC1 PLXND1 ITGA1 ITGB1 PLXNA1 PLXNA2 PLXNB3 TREM2 SEMA6A SEMA4A TYROBP SEMA6D SEMA7A SEMA5A SEMA3E +REACTOME_ACTIVATION_OF_RAC http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_RAC PAK4 GPC1 NCK1 PAK1 PAK2 PAK6 PAK7 RAC1 ROBO1 SOS1 SOS2 LOC729030 NCK2 SLIT2 +REACTOME_PURINE_SALVAGE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PURINE_SALVAGE ADA ADK ADAL DCK DGUOK AMPD1 AMPD2 AMPD3 GMPR HPRT1 APRT PNP GMPR2 +REACTOME_G_ALPHA_I_SIGNALLING_EVENTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G_ALPHA_I_SIGNALLING_EVENTS INSL5 RGS19 NMUR1 CXCL13 CXCR6 GNB5 RRH ADCY1 ADCY2 CCR9 CCL27 NMU ADCY3 ADCY5 ADCY6 GPR44 HRH3 CHRM2 ADCY7 ADCY8 ADCY9 RLN3 CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CNR1 CNR2 NMS ADORA1 ADORA3 ADRA2A ADRA2B OXER1 DRD2 DRD3 AGT AGTR2 APLNR S1PR1 LPAR1 S1PR3 ADCY4 OPN5 LPAR3 FPR1 FPR2 FPR3 OPN3 GABBR1 NPB GALR1 OPN1MW GNAI1 GNAI2 GNAI3 GNAS GNAT1 GNAT2 GNAZ GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 CCR10 NPBWR1 NPBWR2 CXCR3 NPW GPR17 GPR18 MCHR1 GPER CXCL1 CXCL2 CXCL3 ANXA1 HTR1A HTR1B HTR1D HTR1E HTR1F HTR5A HCAR2 RXFP4 APP IL8 CXCR1 CXCR2 CXCL10 KNG1 CXCL9 RGS21 MTNR1A MTNR1B NPY NPY1R NPY2R NPY5R OPRD1 OPRK1 OPRL1 OPRM1 P2RY4 HEBP1 GAL RXFP3 PDYN GNG13 PENK PF4 S1PR5 PMCH PNOC P2RY13 GNG2 POMC PPBP PPY PPYR1 GNG12 CCL28 NMUR2 PYY CXCR7 PTGER3 CXCL16 HRH4 GNB4 OPN1LW RGR RGS1 RGS4 RGS7 RGS12 RHO OPN1SW BDKRB1 BDKRB2 SAA1 CCL5 CCL16 CCL19 CCL20 CCL21 CCL25 CXCL6 CXCL11 CXCL5 CXCL12 CXCR5 RGS18 P2RY12 LOC652222 LOC653879 SST SSTR1 SSTR2 SSTR3 SSTR4 SSTR5 C3 C3AR1 C5 C5AR1 OPN1MW2 CXCR4 MCHR2 CASR GALR3 RGS8 RGS20 S1PR4 RGS11 RGS9 GALR2 HCAR3 LPAR2 GPR55 S1PR2 GNG8 GABBR2 RGS6 P2RY14 +REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION SEMA3A CFL1 FES FYN HSP90AA1 HSP90AB1 LIMK1 PAK1 PAK2 PLXNA1 PLXNA2 PLXNA3 RAC1 LOC644816 NRP1 +REACTOME_CD28_DEPENDENT_VAV1_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CD28_DEPENDENT_VAV1_PATHWAY FYN GRB2 LCK PAK1 PAK2 RAC1 VAV1 CD28 CD80 CD86 CDC42 +REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING MYL12B MYL9 SEMA4D ERBB2 ARHGEF12 RND1 ARHGAP35 RHOA RHOB RHOC RHOG LIMK1 LIMK2 MET MYH9 MYH10 MYH11 MYL6 PLXNB1 PTPRC RAC1 RAC2 ROCK1 RRAS MYL8P LOC642076 ROCK1P1 MYH14 ROCK2 CD72 ARHGEF11 CDC42 +REACTOME_SEMAPHORIN_INTERACTIONS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SEMAPHORIN_INTERACTIONS PLXNC1 CDK5 SEMA3A MYL12B MYL9 SEMA4D DPYSL4 CFL1 CRMP1 DPYSL2 DPYSL3 ERBB2 FES PLXND1 ARHGEF12 PIP5K1C FYN RND1 ARHGAP35 HSP90AA1 HSP90AB1 ITGA1 ITGB1 RHOA RHOB RHOC RHOG LIMK1 LIMK2 MET MYH9 MYH10 MYH11 MYL6 PAK1 PAK2 PLXNA1 PLXNA2 PLXNB1 PLXNB3 TREM2 PLXNA3 DPYSL5 SEMA6A PTPRC RAC1 RAC2 ROCK1 RRAS MYL8P LOC642076 SEMA4A LOC644816 TLN1 ROCK1P1 TYROBP MYH14 SEMA6D SEMA7A NRP1 CDK5R1 SEMA5A ROCK2 CD72 SEMA3E ARHGEF11 FARP2 CDC42 +REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE MYL12B MYL9 SEMA4D ERBB2 ARHGEF12 RND1 RHOA RHOB RHOC RHOG LIMK1 LIMK2 MYH9 MYH10 MYH11 MYL6 PLXNB1 RAC1 RAC2 ROCK1 MYL8P LOC642076 ROCK1P1 MYH14 ROCK2 ARHGEF11 CDC42 +REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION SEMA3A FES PIP5K1C FYN RND1 PLXNA1 PLXNA2 PLXNA3 RAC1 RRAS TLN1 NRP1 FARP2 +REACTOME_LYSOSOME_VESICLE_BIOGENESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_LYSOSOME_VESICLE_BIOGENESIS AP1M2 AP1S1 CLTA CLTC CTSZ AP1B1 AP1G1 DNASE2 DNM2 BLOC1S1 GNS HSPA8 ARF1 M6PR ARRB1 SH3GL2 VAMP2 VAMP7 TXNDC5 VAMP8 AP1S2 AP1M1 DNAJC6 +REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA AKT3 GNB5 PIK3R6 AKT1 AKT2 PIK3R5 GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 RHOA PDPK1 GNG13 PIK3CG GNG2 GNG12 GNB4 GNG8 +REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS SLC22A7 SLC2A6 SLC6A14 SLC2A13 SLC5A11 SLC22A12 SLC44A3 SLC31A1 CP SLC47A2 SLC30A7 SLC2A12 SLC2A7 SLC30A8 SLC44A5 SLC44A1 SLC16A8 SLC41A1 SLC39A6 SLC39A1 SLC39A5 SLC13A5 SLC39A3 SLC39A2 SLC2A8 SLC40A1 SLC6A19 SLC10A6 SLC6A18 SLC22A18 RHCG SLC6A20 SLC6A15 SLC47A1 SLC22A15 SLC39A4 SLC22A11 SLC2A9 SLC44A2 SLC39A10 RHAG SLC5A7 SLC39A8 SLC13A3 SLC30A5 SLC2A1 SLC2A2 SLC2A3 SLC2A4 SLC2A5 SLC5A1 SLC5A2 SLC5A3 SLC6A1 SLC6A2 SLC6A3 SLC6A6 SLC6A7 SLC6A9 SLC6A11 SLC6A12 SLC11A1 SLC13A1 SLC14A1 SLC16A1 SLC18A1 SLC18A2 SLC22A1 SLC22A3 SLC22A2 SLC22A4 SLC22A5 SLC2A11 SLC30A1 SLC30A2 SLC30A3 SLC39A7 SLC44A4 SLC2A10 SLC14A2 SLC41A2 SLC22A16 SLC13A2 SLC16A3 SLC6A5 SLC16A7 SLC22A6 SLC22A8 HEPH +REACTOME_SPHINGOLIPID_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SPHINGOLIPID_METABOLISM COL4A3BP SPTLC1 NEU3 DEGS2 ACER1 NEU4 SGPP2 CSNK1G2 PPM1L ARSK SGMS2 CERS3 ARSG KDSR CERS6 GALC SUMF2 SGMS1 GBA GLA GLB1 GM2A SUMF1 CERS2 HEXA HEXB ENPP7 ARSI ACER2 ARSH ARSA ARSB STS ARSE ARSF ASAH1 NEU1 NEU2 OSBP CTSA ACER3 SMPD3 SMPD4 PRKD1 PSAP ASAH2 SPHK2 GBA2 GBA3 CERK ASAH2C SMPD1 SMPD2 LOC729155 UGCG CERS4 ARSJ SGPP1 DEGS1 PPAP2A PPAP2C PPAP2B SPHK1 SGPL1 CERS5 VAPB VAPA GAL3ST1 SPTLC2 +REACTOME_PD1_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PD1_SIGNALING CSK CD274 HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DRB1 HLA-DRB3 HLA-DRB5 LCK PDCD1 PTPN6 PDCD1LG2 CD3D CD3E CD3G CD247 CD4 +REACTOME_G_ALPHA_S_SIGNALLING_EVENTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G_ALPHA_S_SIGNALLING_EVENTS CALCRL RAMP2 RAMP1 RAMP3 GNB5 ADCY1 ADCY2 CGA PDE10A ADCY3 ADCY5 ADCY6 ADCY7 PTH2 ADCY8 ADCY9 ADCYAP1 ADCYAP1R1 RLN3 RXFP2 ADM TAAR1 ADORA2A ADORA2B CRH CRHR2 GPBAR1 ADRB1 ADRB2 ADRB3 DRD1 DRD5 ADCY4 FSHB FSHR GCG GCGR GHRH GHRHR GIP GIPR PDE7B GLP1R GNAI1 GNAI2 GNAI3 GNAS GNAZ GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 TAAR6 HRH2 HTR4 HTR6 HTR7 IAPP INSL3 NPSR1 LHB LHCGR MC1R MC2R MC3R MC4R MC5R P2RY11 PDE11A PDE1A PDE2A PDE3A PDE3B PDE4B PDE4C PDE4D PDE7A PDE8A PDE1B GNG13 GNG2 POMC AVP AVPR2 GNG12 PTGDR PTGER2 PTGER4 PTGIR PTH PTHLH PTH1R PTH2R GNB4 RXFP1 NPS RLN2 SCT SCTR TSHB TSHR LOC730002 VIP VIPR1 VIPR2 CALCA CALCB ADM2 TAAR8 PDE8B TAAR5 TAAR2 GLP2R GNG8 +REACTOME_CELL_CELL_JUNCTION_ORGANIZATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_CELL_JUNCTION_ORGANIZATION CDH2 CDH3 CDH4 CDH5 CDH6 CDH7 CDH8 CDH9 CDH10 CDH11 CDH12 CDH13 CDH15 CDH18 INADL CLDN16 CLDN4 CLDN3 CLDN7 CLDN19 CTNNA1 CTNNB1 CTNND1 CLDN14 CADM1 CLDN15 CADM2 PVRL3 CLDN17 JUP CLDN20 CLDN11 F11R PARD6A CLDN18 CLDN22 PRKCI PARD3 PVR PVRL1 PVRL2 MPP5 CDH24 CLDN5 PVRL4 PARD6G PARD6B CLDN12 CLDN10 CLDN8 CLDN6 CLDN2 CLDN1 CLDN9 CRB3 CDH1 +REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS RGS19 GNB5 ADCY1 ADCY2 ADCY3 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADRA2A ADRA2B ADCY4 RGS17 GNAI1 GNAI2 GNAI3 GNAS GNAZ GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GNG13 GNG2 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCQ GNG12 GNB4 RGS4 RGS20 GNG8 +REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS SLC2A6 SLC2A12 SLC2A7 SLC2A8 SLC2A9 SLC2A1 SLC2A2 SLC2A3 SLC2A4 SLC2A5 SLC2A11 SLC2A10 +REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY AKT3 THEM4 MAP3K8 CSK CTLA4 BTLA AKT1 AKT2 ICOSLG MTOR RICTOR FYN GRB2 CD274 ICOS HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DRB1 HLA-DRB3 HLA-DRB5 LCK LYN PAK1 PAK2 PDCD1 PDPK1 PIK3CA PIK3R1 PIK3R2 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E TRIB3 PTPN6 RAC1 MLST8 SRC LOC729120 VAV1 YES1 MAPKAP1 PDCD1LG2 PIK3R3 TNFRSF14 MAP3K14 CD3D CD3E CD3G CD247 CD4 CD28 GRAP2 CD80 CD86 CDC42 +REACTOME_SIGNALING_BY_ROBO_RECEPTOR http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_ROBO_RECEPTOR PAK4 CAP2 CAP1 CLASP1 SRGAP2 ABL1 ABL2 GPC1 NCK1 PAK1 PAK2 EVL PFN1 PFN2 ENAH PAK6 PAK7 SRGAP1 RAC1 ROBO1 ROBO2 ROBO3 SOS1 SOS2 LOC729030 VASP NCK2 SLIT2 SRGAP3 CDC42 +REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING AKT3 THEM4 MAP3K8 AKT1 AKT2 MTOR RICTOR FYN LCK PDPK1 PIK3CA PIK3R1 PIK3R2 TRIB3 MLST8 LOC729120 MAPKAP1 PIK3R3 MAP3K14 CD28 CD80 CD86 +REACTOME_TIGHT_JUNCTION_INTERACTIONS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TIGHT_JUNCTION_INTERACTIONS INADL CLDN16 CLDN4 CLDN3 CLDN7 CLDN19 CLDN14 CLDN15 CLDN17 CLDN20 CLDN11 F11R PARD6A CLDN18 CLDN22 PRKCI PARD3 MPP5 CLDN5 PARD6G PARD6B CLDN12 CLDN10 CLDN8 CLDN6 CLDN2 CLDN1 CLDN9 CRB3 +REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING AKT3 GNB5 PIK3R6 AKT1 AKT2 PLCB1 PIK3R5 GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 RHOA PDPK1 GNG13 PIK3CG PLCB2 PLCB3 GNG2 GNG12 GNB4 GNG8 +REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES SLC9A6 SLC34A2 SLC12A7 SLC26A1 SLC38A3 SLC7A9 SLC6A14 SLC26A9 SLC26A7 SLC16A10 SLC15A4 SLC24A4 SLC43A2 SLC32A1 SLC34A3 SLC25A10 SLC36A2 SLC5A8 SLC26A3 SLC26A2 SLC36A1 SLC9A8 SLC7A8 SLC7A11 SLC17A8 SLC24A2 SLC17A5 SLC24A5 SLC9A9 SLC6A19 SLC6A18 SLC9A4 SLC15A3 SLC26A4 SLC38A2 SLC6A20 SLC38A4 SLC6A15 SLC7A10 SLC17A7 SLC17A6 SLC24A3 SLC12A5 SLC4A5 SLC26A6 SLC1A1 SLC1A2 SLC1A3 SLC4A3 SLC1A4 SLC1A5 SLC1A6 SLC1A7 SLC3A1 SLC3A2 SLC4A1 SLC4A2 LOC652661 SLC5A5 SLC6A6 SLC6A12 SLC7A1 SLC7A2 SLC8A2 SLC8A1 SLC8A3 SLC9A1 SLC9A2 SLC9A3 SLC9A5 SLC12A1 SLC12A2 SLC12A4 SLC15A1 SLC15A2 SLC17A1 SLC34A1 SLC20A1 SLC20A2 SLC24A6 SLC7A5 SLC38A1 SLC4A9 SLC9A7 SLC7A3 SLC43A1 SLC4A4 SLC7A7 SLC7A6 SLC24A1 SLC38A5 SLC4A7 SLC4A8 SLC12A6 +REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS AP1M2 TGOLN2 AP4B1 AP1S1 AP3S1 CLTA CLTC CPD SH3D19 AP1B1 AP1G1 DNM2 AP4E1 SNAPIN FTH1 FTL GAK NECAP1 PLDN BLOC1S1 SNX5 YIPF6 HSPA8 IGF2R ARF1 BLOC1S3 ARRB1 OCRL SNX9 PIK3C2A TBC1D8B CNO RAB5C SORT1 SH3GL2 SNX2 VAMP2 VAMP7 TFRC TPD52 TPD52L1 LOC643454 TXNDC5 PICALM DTNBP1 AP3B1 VAMP8 NAPA AP1S2 AP1M1 HIP1R PUM1 DNAJC6 +REACTOME_CTLA4_INHIBITORY_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CTLA4_INHIBITORY_SIGNALING AKT3 CTLA4 AKT1 AKT2 FYN LCK LYN PDPK1 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E SRC YES1 CD80 CD86 +REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX CDK7 ERCC8 ERCC1 ERCC2 ERCC3 ERCC4 ERCC5 ERCC6 GTF2H1 GTF2H2 GTF2H3 GTF2H4 MNAT1 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L XAB2 LOC652857 GTF2H2B TCEA1 CCNH +REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS SLC38A3 SLC7A9 SLC6A14 SLC16A10 SLC15A4 SLC43A2 SLC32A1 SLC25A10 SLC36A2 SLC5A8 SLC36A1 SLC7A8 SLC7A11 SLC17A8 SLC17A5 SLC6A19 SLC6A18 SLC15A3 SLC38A2 SLC6A20 SLC38A4 SLC6A15 SLC7A10 SLC17A7 SLC17A6 SLC1A1 SLC1A2 SLC1A3 SLC1A4 SLC1A5 SLC1A6 SLC1A7 SLC3A1 SLC3A2 SLC5A5 SLC6A6 SLC6A12 SLC7A1 SLC7A2 SLC15A1 SLC15A2 SLC17A1 SLC7A5 SLC38A1 SLC7A3 SLC43A1 SLC7A7 SLC7A6 SLC38A5 +REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX PSMD14 PSMA8 PSME4 ORC6 ORC3 ORC1 ORC2 ORC4 ORC5 GMNN PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RPS27A LOC652826 RPS27AP11 UBA52 CDT1 MCM8 PSMF1 PSMD6 CDC6 +REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM HIBADH DBT DLD HIBCH ACAD8 HSD17B10 ACADSB IVD ACAT1 ALDH6A1 AUH MCCC1 BCAT1 BCAT2 BCKDHA BCKDHB MCCC2 +REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER POLD3 PCNA POLD1 POLD2 POLE POLE2 POLD4 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 +REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR ADAM10 JAG1 DLL1 JAG2 NOTCH2 NOTCH3 NOTCH4 DLL4 RPS27A ADAM17 RPS27AP11 UBA52 +REACTOME_SYNTHESIS_OF_DNA http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_DNA CDK2 PSMD14 CDKN1A CDKN1B POLD3 PSMA8 DNA2 FEN1 PSME4 ORC6 ORC3 POLA2 LIG1 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 ORC1 ORC2 ORC4 ORC5 PCNA GINS2 POLA1 POLD1 POLD2 POLE POLE2 PRIM1 PRIM2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 POLD4 RB1 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 RPS27A LOC652826 RPS27AP11 UBA52 CDT1 CDC45 GINS4 MCM8 CCNA2 CCNA1 PSMF1 GINS1 PSMD6 CDC6 +REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS SLC6A14 SLC6A19 SLC6A18 SLC6A20 SLC6A15 SLC6A1 SLC6A2 SLC6A3 SLC6A6 SLC6A7 SLC6A9 SLC6A11 SLC6A12 SLC18A1 SLC18A2 SLC22A2 SLC6A5 +REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE A2M F2 F3 F5 F7 F8 F9 F10 F11 F12 F13A1 F13B FGA FGB FGG GP1BA GP1BB GP5 GP9 KLKB1 KNG1 SERPINC1 PF4 PF4V1 PRCP PROC PROS1 TFPI THBD C1QBP SERPING1 VWF +REACTOME_DEADENYLATION_OF_MRNA http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DEADENYLATION_OF_MRNA PAIP1 EIF4A1 EIF4A2 EIF4B EIF4E EIF4G1 CNOT10 PABPC1 CNOT7 CNOT2 CNOT3 CNOT4 PARN C2orf29 CNOT6 LOC645139 LOC651789 LOC652607 TNKS1BP1 RQCD1 CNOT8 EIF4A3 +REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE LSM6 DDX6 DCP2 DCP1B PATL1 EDC4 LSM5 LSM4 LSM1 LSM3 XRN1 DCP1A LSM2 LOC645947 EDC3 +REACTOME_SIGNAL_AMPLIFICATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNAL_AMPLIFICATION GNA13 GNB5 MAPK14 GNA11 GNA15 GNAI1 GNAI2 GNAI3 GNAQ GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 P2RY1 GNG13 PLA2G4A GNG2 GNG12 GNB4 P2RY12 SRC TBXA2R GNG8 GNA14 +REACTOME_ZINC_TRANSPORTERS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ZINC_TRANSPORTERS SLC30A7 SLC30A8 SLC39A6 SLC39A1 SLC39A5 SLC39A3 SLC39A2 SLC39A4 SLC39A10 SLC39A8 SLC30A5 SLC30A1 SLC30A2 SLC30A3 SLC39A7 +REACTOME_DOUBLE_STRAND_BREAK_REPAIR http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DOUBLE_STRAND_BREAK_REPAIR RAD50 XRCC6 H2AFX LOC389901 LIG1 LIG4 MRE11A NBN ATM TDP1 PRKDC RAD51 RAD52 RPA1 RPA2 RPA3 LOC651610 BRCA1 BRCA2 TP53BP1 XRCC4 XRCC5 BRIP1 MDC1 +REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR AKAP9 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D HRAS NEFL RASGRF1 RASGRF2 CALM1 CALM2 CALM3 CAMK2A CAMK2B CAMK2D ACTN2 +REACTOME_METAL_ION_SLC_TRANSPORTERS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METAL_ION_SLC_TRANSPORTERS SLC31A1 CP SLC30A7 SLC30A8 SLC41A1 SLC39A6 SLC39A1 SLC39A5 SLC39A3 SLC39A2 SLC40A1 SLC39A4 SLC39A10 SLC39A8 SLC30A5 SLC11A1 SLC30A1 SLC30A2 SLC30A3 SLC39A7 SLC41A2 HEPH +REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 PSMD14 PSMA8 PSME4 ATM PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RPS27A RFWD2 LOC651610 LOC652826 TP53 RPS27AP11 RFWD2P1 UBA52 PSMF1 PSMD6 +REACTOME_SMOOTH_MUSCLE_CONTRACTION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SMOOTH_MUSCLE_CONTRACTION SORBS3 MYL12B MYL9 SORBS1 MYL6B LMOD1 ITGA1 ITGB5 MYH11 MYL6 MYLK ACTA2 MYL8P LOC642076 TLN1 TPM1 TPM2 TPM3 TPM4 ACTG2 VCL CALD1 CALM1 CALM2 CALM3 +REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS AKAP9 ADCY1 ADCY3 ADCY8 CREB1 RPS6KA6 GRIA1 GRIA2 GRIA3 GRIA4 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D HRAS NEFL PDPK1 PRKACB MAPK1 RAF1 RASGRF1 RASGRF2 RPS6KA1 RPS6KA2 RPS6KA3 RRAS BRAF CALM1 CALM2 CALM3 CAMK4 CAMK2A CAMK2B CAMK2D CAMKK1 ACTN2 +REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS AKAP9 CREB1 RPS6KA6 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D HRAS NEFL PDPK1 MAPK1 RAF1 RASGRF1 RASGRF2 RPS6KA1 RPS6KA2 RPS6KA3 RRAS BRAF CALM1 CALM2 CALM3 CAMK2A CAMK2B CAMK2D ACTN2 +REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS AKAP9 ADCY1 ADCY3 ADCY8 CREB1 RPS6KA6 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D HRAS NEFL PDPK1 PRKACB MAPK1 RAF1 RASGRF1 RASGRF2 RPS6KA1 RPS6KA2 RPS6KA3 RRAS BRAF CALM1 CALM2 CALM3 CAMK4 CAMK2A CAMK2B CAMK2D CAMKK1 ACTN2 +REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION AKAP9 GRIA1 GRIA2 GRIA3 GRIA4 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D NEFL CAMK2A CAMK2B CAMK2D ACTN2 +REACTOME_METABOLISM_OF_MRNA http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_MRNA PSMD14 PAIP1 RNPS1 LSM6 RPL35 EXOSC8 EXOSC6 MAPK14 PSMA8 RPL7AP27 DDX6 DCP2 DCP1B EIF4A1 EIF4A2 EIF4B EIF4E EIF4G1 ELAVL1 AKT1 ETF1 FAU PATL1 CASC3 DIS3 NCBP2 EXOSC7 SMG1 PSME4 SMG6 SMG5 EXOSC2 RPL13A EDC4 LSM5 GSPT2 LSM4 RPL36 CNOT10 UPF2 PABPC1 LSM1 LSM3 RPL10P16 FAM153A DCPS CNOT7 HNRNPD HSPA1B HSPA8 HSPB1 RPL36P14 TNPO1 RPSAP12 RPS8P10 RPL7AP66 RPL10P9 RPS12P4 RPSA RPS26P10 RPL23AP2 MAGOH RPS12P22 RPL21P29 RPS26P35 NCBP1 RPL10A CNOT2 CNOT3 CNOT4 PARN EXOSC3 EXOSC1 RPL26L1 EXOSC9 XRN1 EXOSC4 PPP2CA PPP2R1A SMG8 PPP2R2A C2orf29 PRKCA PRKCD DCP1A MAPK11 SMG9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 EXOSC5 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 CNOT6 LSM2 RPL3 RPL3L RPL4 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL10 RPL11 RPL12 RPL13 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL23A RPL24 RPL26 RPL27 RPL30 RPL27A RPL28 RPL29 RPL31 RPL32 RPL34 RPL35A RPL37 RPL37A RPL38 RPL39 RPL41 RPL36A RPLP0 RPLP1 RPLP2 RPS2 RPS3 RPS3A RPS4X RPS4Y1 RPS5 RPS6 RPS7 RPS8 RPS9 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS18 RPS19 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS28 RPS29 RPL6P19 LOC641895 RPL36AP31 RPS29P3 RPS26P28 RPL36AP8 RPL26P22 LOC643446 RPS26P20 RPS15AP11 RPS26P50 LOC645139 RPL22P11 RPL17P6 RPS13P8 RPS28P4 LOC645947 RPL32P16 LOC646184 RPS28P7 RPL12P2 LOC647074 RPL23AP42 RPL5P1 RPL36AP51 LOC649602 RPS28P9 UPF3B UPF3A RPL34P27 LOC651789 LOC651825 LOC651894 LOC652607 LOC652826 RPL26P30 RPSAP9 RPL19P9 RPL21P119 RPL31P17 LOC653881 ZFP36L1 RPL31P31 RPL15P17 RPL23AP18 RPL26P24 RPL21P75 RPS27AP11 RPS26P7 RPL21P134 RPS26P25 RPS19P3 RPL36AP23 RPS18P10 RPL17P36 RPL36AP37 RPL21P16 RPL23AP74 RPS15P5 RPL23AP63 RPS10P9 LOC730343 RPS18P5 UBA52 RPL34P31 XPO1 YWHAB YWHAZ ZFP36 EDC3 NUP214 ANP32A TNKS1BP1 KHSRP TNFSF13 RPL14 RQCD1 MAPKAPK2 CNOT8 RPL23 PSMF1 EIF4A3 PSMD6 SMG7 RBM8A +REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE EXOSC8 EXOSC6 DIS3 EXOSC7 EXOSC2 DCPS EXOSC3 EXOSC1 EXOSC9 EXOSC4 EXOSC5 +REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS SLC47A2 SLC16A8 SLC13A5 SLC10A6 SLC47A1 SLC13A3 SLC13A1 SLC16A1 SLC13A2 SLC16A3 SLC16A7 +REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY PAIP1 LSM6 EXOSC8 EXOSC6 DDX6 DCP2 DCP1B EIF4A1 EIF4A2 EIF4B EIF4E EIF4G1 PATL1 DIS3 EXOSC7 EXOSC2 EDC4 LSM5 LSM4 CNOT10 PABPC1 LSM1 LSM3 DCPS CNOT7 CNOT2 CNOT3 CNOT4 PARN EXOSC3 EXOSC1 EXOSC9 XRN1 EXOSC4 C2orf29 DCP1A EXOSC5 CNOT6 LSM2 LOC645139 LOC645947 LOC651789 LOC652607 EDC3 TNKS1BP1 RQCD1 CNOT8 EIF4A3 +REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII AKAP9 CREB1 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D NEFL CALM1 CALM2 CALM3 CAMK2A CAMK2B CAMK2D ACTN2 +REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR GNA13 GNB5 GNA11 GNA15 GNAQ GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GNG13 GNG2 GNG12 GNB4 TBXA2R GNG8 GNA14 +REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS FERMT2 FLNC PARVB ILK ITGB1 LIMS1 FBLIM1 PARVA RSU1 TESK1 LIMS3 VASP ACTN1 ARHGEF6 +REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 GNB5 GNAI1 GNAI2 GNAI3 GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GNG13 GNG2 GNG12 GNB4 P2RY12 GNG8 +REACTOME_CELL_JUNCTION_ORGANIZATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CELL_JUNCTION_ORGANIZATION CDH2 CDH3 CDH4 CDH5 CDH6 CDH7 CDH8 CDH9 CDH10 CDH11 CDH12 CDH13 CDH15 CDH18 INADL CLDN16 FERMT2 COL17A1 CLDN4 CLDN3 CLDN7 CLDN19 CTNNA1 CTNNB1 CTNND1 FLNC CLDN14 CADM1 CLDN15 CADM2 PVRL3 CLDN17 PARVB ILK ITGB1 ITGB4 JUP LAMA3 LAMB3 LAMC2 LIMS1 CLDN20 CLDN11 F11R PARD6A CLDN18 PLEC CLDN22 FBLIM1 PARVA PRKCI PARD3 PVR PVRL1 PVRL2 RSU1 MPP5 CDH24 LOC652460 TESK1 CLDN5 LIMS3 VASP PVRL4 PARD6G PARD6B ACTN1 CLDN12 CLDN10 CLDN8 CLDN6 CLDN2 CLDN1 CLDN9 CRB3 ARHGEF6 CD151 CDH1 +REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS SLC6A14 SLC44A3 SLC44A5 SLC44A1 SLC6A19 SLC6A18 RHCG SLC6A20 SLC6A15 SLC44A2 RHAG SLC5A7 SLC6A1 SLC6A2 SLC6A3 SLC6A6 SLC6A7 SLC6A9 SLC6A11 SLC6A12 SLC14A1 SLC18A1 SLC18A2 SLC22A2 SLC44A4 SLC14A2 SLC6A5 +REACTOME_PYRUVATE_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PYRUVATE_METABOLISM DLAT DLD SLC16A8 LDHA LDHB PDHA1 PDHB PDK1 PDK2 PDK3 PDK4 PDP1 PDPR PDP2 LOC650883 SLC16A1 BSG PDHX SLC16A3 +REACTOME_PURINE_CATABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PURINE_CATABOLISM NT5C2 GPX1 NT5C PNP NT5E XDH NT5C1A CAT NT5C1B GDA +REACTOME_GLUCOSE_TRANSPORT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLUCOSE_TRANSPORT NUP50 NUPL2 NUP35 NUP205 NUP210 NUP188 NUP62 G6PC SLC37A4 GCK GCKR HK1 HK2 HK3 NUP43 NUP88 NUP54 NUP133 NUP107 G6PC2 RANBP2 SLC2A1 SLC2A2 SLC2A3 SLC2A4 TPR NUP37 NUP85 NUP214 AAAS SEH1L RAE1 G6PC3 NUP155 NUP93 NUPL1 POM121 NUP153 +REACTOME_FRS2_MEDIATED_CASCADE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FRS2_MEDIATED_CASCADE FRS3 FRS2 KLB FGF1 FGF2 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGF10 FGFR1 FGFR3 FGFR2 FGFR4 FGF20 FGF22 GRB2 HRAS KRAS NRAS MAPK1 MAPK3 MAP2K1 MAP2K2 RAF1 SOS1 YWHAB FGF23 FGF18 FGF17 KL CDK1 FGF19 +REACTOME_METABOLISM_OF_RNA http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_RNA SNUPN PSMD14 PRMT5 PAIP1 NUP50 RNPS1 NUPL2 LSM6 DDX20 RPL35 EXOSC8 EXOSC6 SNRPD2P1 CLNS1A NUP35 MAPK14 PSMA8 RPL7AP27 DDX6 DCP2 DCP1B EIF4A1 EIF4A2 EIF4B EIF4E EIF4G1 ELAVL1 AKT1 ETF1 FAU PATL1 CASC3 DIS3 NCBP2 EXOSC7 SMG1 NUP205 PSME4 NUP210 SMG6 SMG5 EXOSC2 NUP188 RPL13A NUP62 EDC4 LSM5 GSPT2 LSM4 RPL36 CNOT10 GEMIN5 UPF2 PABPC1 LSM1 LSM3 RPL10P16 FAM153A DCPS CNOT7 HNRNPD HSPA1B HSPA8 HSPB1 RPL36P14 NUP43 TNPO1 RPSAP12 RPS8P10 RPL7AP66 RPL10P9 RPS12P4 RPSA RPS26P10 RPL23AP2 MAGOH RPS12P22 RPL21P29 RPS26P35 NCBP1 RPL10A CNOT2 CNOT3 CNOT4 NUP88 GEMIN4 PARN EXOSC3 EXOSC1 RPL26L1 PHAX NUP54 EXOSC9 XRN1 EXOSC4 PPP2CA PPP2R1A SMG8 PPP2R2A C2orf29 NUP133 PRKCA PRKCD DCP1A MAPK11 SMG9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 EXOSC5 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 NUP107 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 CNOT6 LSM2 RANBP2 RPL3 RPL3L RPL4 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL10 RPL11 RPL12 RPL13 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL23A RPL24 RPL26 RPL27 RPL30 RPL27A RPL28 RPL29 RPL31 RPL32 RPL34 RPL35A RPL37 RPL37A RPL38 RPL39 RPL41 RPL36A RPLP0 RPLP1 RPLP2 RPS2 RPS3 RPS3A RPS4X RPS4Y1 RPS5 RPS6 RPS7 RPS8 RPS9 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS18 RPS19 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS28 RPS29 RPL6P19 LOC641895 RPL36AP31 RPS29P3 RPS26P28 RPL36AP8 RPL26P22 LOC643446 RPS26P20 RPS15AP11 RPS26P50 LOC645139 RPL22P11 RPL17P6 RPS13P8 RPS28P4 LOC645947 RPL32P16 LOC646184 RPS28P7 RPL12P2 LOC647074 RPL23AP42 RPL5P1 RPL36AP51 LOC649602 RPS28P9 UPF3B UPF3A RPL34P27 LOC651789 LOC651825 LOC651894 LOC652607 LOC652826 RPL26P30 RPSAP9 RPL19P9 RPL21P119 RPL31P17 LOC653881 SMN1 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG ZFP36L1 TPR RPL31P31 RPL15P17 RPL23AP18 RPL26P24 RPL21P75 RPS27AP11 RPS26P7 RPL21P134 RPS26P25 RPS19P3 RPL36AP23 RPS18P10 RPL17P36 RPL36AP37 RPL21P16 RPL23AP74 RPS15P5 RPL23AP63 RPS10P9 LOC730343 RPS18P5 UBA52 RPL34P31 XPO1 YWHAB YWHAZ ZFP36 NUP37 WDR77 GEMIN7 GEMIN6 NUP85 EDC3 NUP214 AAAS ANP32A SEH1L RAE1 GEMIN2 TNKS1BP1 KHSRP TNFSF13 RPL14 RQCD1 MAPKAPK2 CNOT8 RPL23 PSMF1 NUP155 TGS1 NUP93 EIF4A3 NUPL1 PSMD6 POM121 SMG7 RBM8A NUP153 +REACTOME_MITOTIC_G1_G1_S_PHASES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MITOTIC_G1_G1_S_PHASES CDK2 CDK4 CDK6 PSMD14 CDK7 CDKN1A CDKN1B CDKN2A CDKN2B CDKN2C CDKN2D DBF4 CKS1B LIN54 DHFR DYRK1A E2F1 E2F2 E2F3 E2F4 E2F5 ORC6 ORC3 POLA2 FBXO5 PPP2R3B LIN9 RPA4 HDAC1 MAX MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MNAT1 LOC441488 MYBL2 MYC ORC1 ORC2 ORC4 ORC5 PCNA POLA1 POLE POLE2 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A MCM10 PRIM1 PRIM2 LIN37 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RB1 RBBP4 RBL1 RBL2 CCND1 RPA1 RPA2 RPA3 RPS27A RRM2 RBBP4P1 DHFRP1 LOC645084 SKP1 SKP2 LOC652826 TFDP1 TK2 RPS27AP11 TYMS LOC729964 UBA52 WEE1 CDT1 CDC7 CDC45 MCM8 CUL1 CCNA2 CCNA1 CCNB1 CCND2 CCND3 CCNE1 CCNH PKMYT1 CCNE2 LIN52 PSMF1 CDK1 PSMD6 CDC6 CDC25A +REACTOME_PI_3K_CASCADE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PI_3K_CASCADE AKT3 CDKN1A CDKN1B FRS2 CHUK THEM4 CREB1 KLB AKT1 AKT2 FGF1 FGF2 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGF10 FGFR1 FGFR3 FGFR2 FGFR4 FOXO1 FOXO3 PHLPP1 MTOR RICTOR GAB1 FGF20 FGF22 GRB2 GSK3A NR4A1 MDM2 FOXO4 PDPK1 PIK3CA PIK3R1 BAD PTEN TRIB3 RPS6KB2 MLST8 TSC2 LOC729120 LOC731292 MAPKAP1 FGF23 CASP9 AKT1S1 FGF18 FGF17 KL FGF19 +REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR AKT3 CDKN1A CDKN1B ADCY1 ADCY2 FRS3 FRS2 ADCY3 ADCY5 ADCY6 ADCY7 ADCY8 CHUK ADCY9 THEM4 CREB1 KLB ADRBK1 ADCY4 AKT1 AKT2 FGF1 FGF2 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGF10 FGFR1 FGFR3 FGFR2 FGFR4 FOXO1 FOXO3 PHLPP1 MTOR RICTOR GAB1 FGF20 FGF22 GRB2 GSK3A NR4A1 HRAS ITPR2 ITPR3 KRAS MDM2 FOXO4 NRAS PDE1A PDE1B PDPK1 PIK3CA PIK3R1 PLCG1 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCD PRKCE PRKCG MAPK1 MAPK3 MAP2K1 MAP2K2 BAD PTEN TRIB3 RAF1 RPS6KB2 MLST8 SHC1 SOS1 TSC2 LOC729120 LOC730418 LOC731292 YWHAB MAPKAP1 CALM1 CALM2 FGF23 CALM3 CAMK4 CASP9 AKT1S1 FGF18 FGF17 KL CDK1 FGF19 +REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE CDK2 PSMD14 ANAPC10 UBE2C PSMA8 PSME4 CDC26 FBXO5 ANAPC2 ANAPC4 MAD2L1 ANAPC5 ANAPC7 ANAPC11 PLK1 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RPS27A ANAPC1 LOC647654 LOC649620 SKP1 SKP2 LOC650621 LOC651763 LOC652826 AURKA BUB1B RPS27AP11 CDC26P1 LOC730594 UBA52 UBE2D1 UBE2E1 CUL1 CDC14A CDC23 CDC16 CCNA2 CCNA1 CCNB1 BTRC BUB3 AURKB PTTG1 PSMF1 CDK1 PSMD6 CDC20 CDC27 +REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX NOD1 TAB1 CHUK AGER TAB2 TAB3 HMGB1 APP IKBKB IRAK1 IRAK2 NFKB2 NFKBIA NFKBIB RELA S100A12 S100B SAA1 NOD2 MAP3K7 TRAF6 IKBKG RIPK2 +REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 PRKAG2 CAB39 PRKAG3 PPM1A STRADB PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 RPTOR LOC644462 STK11 CAB39L STRADA +REACTOME_MITOTIC_M_M_G1_PHASES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MITOTIC_M_M_G1_PHASES KIF20A CDK2 PSMD14 STAG1 NDC80 CENPA CENPC1 NUDC STAG2 DBF4 KIF2C ZWINT PMF1 PSMA8 SPC24 SGOL2 SGOL1 E2F1 E2F2 E2F3 SKA1 MAPRE1 PSME4 CLASP1 ITGB3BP ORC6 ORC3 POLA2 CENPI AHCTF1 NSL1 FBXO5 RPA4 BIRC5 SKA2 NUP43 INCENP APITD1 KIF2A CENPP MAD2L1 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 ORC1 ORC2 ORC4 ORC5 PAFAH1B1 GMNN PLK1 POLA1 POLE POLE2 ERCC6L CCDC99 PPP1CC ZWILCH CDCA8 PPP2CA PPP2CB CENPQ PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E MCM10 PRIM1 PRIM2 NUP133 CENPN RCC2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 CASC5 PSMD3 PSMD4 PSMD5 NUP107 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 SPC25 TAOK1 RAD21 RANBP2 RANGAP1 RPA1 RPA2 RPA3 RPS27 RPS27A CLIP1 SEC13 CENPK LOC645084 GORASP1 CENPH LOC652826 BUB1 BUB1B RPS27AP11 SKA2L UBA52 XPO1 MIS12 CENPM NUP37 CENPO MLF1IP NUP85 DSN1 CENPT B9D2 NDEL1 CDT1 SEH1L KIF18A SMC1A CDC7 CDC45 NUF2 MAD1L1 MCM8 KIF2B SMC3 CENPL ZW10 BUB3 AURKB PSMF1 KIF23 KNTC1 CKAP5 PSMD6 CDC6 CDC20 +REACTOME_MYOGENESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MYOGENESIS CDH2 CDH4 CDH15 MAPK14 CTNNA1 CTNNB1 ABL1 MEF2A MEF2BNB-MEF2B MEF2C MEF2D MYF5 MYF6 MYOD1 MYOG NEO1 NTN3 CDON MAPK11 MAP2K6 MAPK12 BNIP2 TCF4 TCF3 TCF12 MEF2BNB BOC CDC42 +REACTOME_MAP_KINASE_ACTIVATION_IN_TLR_CASCADE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MAP_KINASE_ACTIVATION_IN_TLR_CASCADE NOD1 TAB1 CREB1 ATF2 MAPK14 DUSP3 DUSP4 DUSP6 DUSP7 ELK1 TAB2 FOS TAB3 IRAK1 IRAK2 JUN MEF2A MEF2C ATF1 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D MAPK1 MAPK3 MAPK7 MAPK8 MAPK11 MAPK9 MAPK10 MAP2K1 MAP2K2 MAP2K3 MAP2K6 MAP2K7 RPS6KA1 RPS6KA2 RPS6KA3 NOD2 MAP2K4 LOC650832 MAP3K7 TRAF6 MAPKAPK3 IKBKG RIPK2 RPS6KA5 MAPKAPK2 CDK1 +REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE ADCY1 ADCY2 ADCY3 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 CREB1 KLB ADRBK1 ADCY4 FGF1 FGF2 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGF10 FGFR1 FGFR3 FGFR2 FGFR4 FGF20 FGF22 ITPR2 ITPR3 PDE1A PDE1B PLCG1 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCD PRKCE PRKCG LOC730418 CALM1 CALM2 FGF23 CALM3 CAMK4 FGF18 FGF17 KL FGF19 +REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING GNB5 DLG1 DLG3 PLCB1 GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GRIK1 GRIK2 GRIK3 GRIK4 GRIK5 GNG13 PLCB2 PLCB3 GNG2 GNG12 GNB4 CALM1 CALM2 CALM3 NCALD GNG8 +REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS DLG1 DLG3 GRIK1 GRIK2 GRIK3 GRIK4 GRIK5 CALM1 CALM2 CALM3 NCALD +REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS ATF2 MAPK14 FOS JUN MAPK1 MAPK3 MAPK8 MAPK11 MAPK9 MAPK10 +REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES CREB1 ATF2 MAPK14 DUSP3 DUSP4 DUSP6 DUSP7 ELK1 FOS JUN MEF2A MEF2C ATF1 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D MAPK1 MAPK3 MAPK7 MAPK8 MAPK11 MAPK9 MAPK10 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA5 MAPKAPK2 +REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES CTPS DTYMK AK1 AK2 AK5 GLRX GSR GUK1 NME1 NME2 NME4 RRM2B CMPK1 CTPS2 RRM1 RRM2 NME1-NME2 TXN TXNRD1 +REACTOME_GPCR_LIGAND_BINDING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GPCR_LIGAND_BINDING INSL5 LPAR6 CALCRL RAMP2 RAMP1 RAMP3 NMUR1 CXCL13 CXCR6 GNB5 RRH CYSLTR1 CCR9 CGA CCL27 NMU NPFFR2 PROKR1 UTS2 FZD10 GPR44 HRH3 CHRM1 CHRM2 PTH2 CHRM3 CHRM5 ADCYAP1 ADCYAP1R1 RLN3 RXFP2 CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCBP2 LTB4R CNR1 CNR2 PROKR2 NMS ADM ADORA1 TAAR1 ADORA2A ADORA2B CRH CRHR2 ADORA3 ADRA1D ADRA1B ADRA1A ADRA2A ADRA2B GPBAR1 CX3CR1 ADRB1 ADRB2 ADRB3 CD55 OXER1 DRD1 DRD2 DRD3 DRD5 AGT AGTR1 AGTR2 APLNR S1PR1 LPAR1 S1PR3 EDN1 EDN2 EDN3 EDNRA EDNRB EMR1 F2 F2R F2RL1 F2RL2 OPN5 GPRC6A LPAR3 FPR1 FPR2 FPR3 OPN3 NTSR2 FSHB FSHR GAST DARC FZD2 GABBR1 NPB UTS2D GALR1 GCG GCGR OPN1MW GHRH GHRHR GHSR GIP GIPR GPR77 P2RY10 GLP1R GNAS GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GNRH1 GNRH2 GNRHR CCR10 GPR4 XCR1 NPBWR1 NPBWR2 CXCR3 PRLHR UTS2R NPW GPR17 GPR18 LPAR4 MCHR1 GPER MLNR GPR39 FFAR1 FFAR3 FFAR2 GRM1 GRM2 GRM3 GRM4 GRM6 GRM7 GRM8 CXCL1 CXCL2 CXCL3 GRP GRPR GPR132 ANXA1 HCRT HCRTR1 HCRTR2 EMR2 TAAR6 HRH1 HRH2 HTR1A HTR1B HTR1D HTR1E HTR1F HTR2A HTR2B HTR2C HTR4 HTR5A HTR6 HTR7 IAPP HCAR2 O3FAR1 RXFP4 QRFP APP IHH IL8 CXCR1 CXCR2 CXCL10 INSL3 KISS1 KNG1 NPSR1 LHB LHCGR CCL3L3 MC1R MC2R MC3R MC4R MC5R CXCL9 MLN MTNR1A MTNR1B NMB NMBR NPY NPY1R NPY2R NPY5R NTS NTSR1 OPRD1 OPRK1 OPRL1 OPRM1 OXT OXTR P2RY1 P2RY2 P2RY4 P2RY6 P2RY11 DHH HEBP1 PRLH GAL RXFP3 WNT16 CCRL1 PDYN GHRL GNG13 PENK PF4 S1PR5 PMCH PNOC P2RY13 GNG2 WNT4 POMC PPBP AVP AVPR1A AVPR1B PPY AVPR2 PPYR1 GNG12 LTB4R2 CCL28 NMUR2 PYY CXCR7 CYSLTR2 PTAFR PTCH1 PTGDR PTGER1 PTGER2 PTGER3 PTGER4 PTGFR PTGIR PTH PTHLH PTH1R PTH2R CXCL16 HRH4 GNB4 RXFP1 NPS OPN1LW RGR RHO RLN2 OPN1SW BDKRB1 BDKRB2 SAA1 SCT SCTR CCL2 CCL3 CCL3L1 CCL4 CCL5 CCL7 CCL11 CCL16 CCL17 CCL19 CCL20 CCL21 CCL22 CCL25 CXCL6 CXCL11 CXCL5 XCL1 CX3CL1 CXCL12 NPFFR1 CXCR5 SHH P2RY12 LOC649279 CCRL1P1 LOC652222 LOC652292 LOC653879 SMO SST SSTR1 SSTR2 SSTR3 SSTR4 SSTR5 BRS3 XCL2 TAC1 TACR2 TAC3 TACR1 TACR3 TBXA2R C3 C3AR1 TRH TRHR TSHB TSHR C5 C5AR1 OPN1MW2 LOC728830 LOC730002 LOC730413 LOC731823 VIP VIPR1 VIPR2 WNT1 WNT2 WNT3 WNT5A WNT6 WNT7A WNT7B WNT8B WNT10B WNT11 WNT2B WNT9A WNT9B CXCR4 FZD5 CALCA CALCB FZD3 ADM2 WNT10A TAS1R2 TAS1R1 GPR68 FZD1 FZD4 FZD6 FZD7 FZD8 FZD9 TAAR8 TAS1R3 QRFPR PROK1 MCHR2 CASR KISS1R EMR3 GPR65 GALR3 NPFF PTCH2 S1PR4 GALR2 HCAR3 CCK CCKAR CCKBR WNT3A F2RL3 TAAR5 LPAR2 TAAR2 GPR55 S1PR2 GLP2R OPN4 GNG8 GABBR2 CD97 P2RY14 +REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION CDK7 SNAPC5 POLR3F POLR3C EHMT2 POLR3A LZTS1 CBX3 HIST4H4 HIST2H3C HIST3H2BB POLR3H ERCC2 ERCC3 ERCC6 HIST1H2BA POLR1A PTRF GTF2H1 GTF2H2 GTF2H3 GTF2H4 BRF1 GTF3C2 HIST1H2AE HIST1H2AD H2AFX H2AFZ HIST1H2BD HIST1H2BB H3F3A H3F3B HIST2H3A H3F3AP5 MNAT1 NFIB POLR1D POLR3K POLR2E POLR2F POLR2H POLR2K POLR2L POLRMT POU2F1 RRN3 BRF2 HIST2H4B POLR3B POLR3E MAPK3 TFB2M H3F3AP6 LOC652857 GTF2H2B HIST2H3D LOC653972 POLR3D SNAPC1 SNAPC2 SNAPC3 SNAPC4 SSB TBP TFAM HIST2H2AA4 LOC731820 UBTF ZNF143 MTERF HIST1H4I HIST1H2AJ HIST1H2AC HIST1H2AB HIST2H2AA3 HIST2H2AC HIST1H2BG HIST1H2BL HIST1H2BN HIST1H2BM HIST1H2BF HIST1H2BE HIST1H2BH HIST1H2BI HIST1H2BC HIST1H2BO HIST2H2BE HIST1H3A HIST1H3D HIST1H3C HIST1H3E HIST1H3I HIST1H3G HIST1H3J HIST1H3H HIST1H3B HIST1H4A HIST1H4D HIST1H4F HIST1H4K HIST1H4J HIST1H4C HIST1H4H HIST1H4B HIST1H4E HIST1H4L HIST2H4A POLR1B POLR3GL HIST1H2BK KAT2B MBD2 HIST1H3F HIST1H2BJ TAF1C TAF1B TAF1A CCNH GTF3C5 GTF3C4 GTF3C3 POLR1C +REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 NOD1 TAB1 TAB2 TAB3 IRAK1 IRAK2 MAPK8 MAPK9 MAPK10 MAP2K7 NOD2 MAP2K4 MAP3K7 TRAF6 IKBKG RIPK2 +REACTOME_SHC_MEDIATED_CASCADE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SHC_MEDIATED_CASCADE KLB FGF1 FGF2 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGF10 FGFR1 FGFR3 FGFR2 FGFR4 FGF20 FGF22 GRB2 HRAS KRAS NRAS SHC1 SOS1 FGF23 FGF18 FGF17 KL FGF19 +REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS GNA13 GNB5 F2 F2R F2RL2 GNA11 GNA12 GNA15 GNAQ GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 ARRB1 ARRB2 GNG13 GNG2 MAPK1 MAPK3 GNG12 GNB4 SRC F2RL3 GNG8 GNA14 +REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK PRKAG2 CAB39 PRKAG3 PPM1A STRADB PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 RPTOR RHEB LOC644462 STK11 TSC1 TSC2 CAB39L STRADA +REACTOME_MITOTIC_G2_G2_M_PHASES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MITOTIC_G2_G2_M_PHASES ACTR1A AKAP9 CDK2 CDK7 TUBB4A TUBB4B TUBGCP3 DCTN2 CETN2 PLK4 SDCCAG8 TUBGCP2 CNTRL FGFR1OP CEP250 DCTN3 TUBGCP5 NEDD1 CSNK1D CSNK1E DCTN1 DYNC1H1 DYNC1I2 E2F1 E2F3 TUBB CEP164 MAPRE1 NINL AZI1 CLASP1 TUBG2 HSP90AA1 MNAT1 LOC440917 NEK2 NUMA1 PAFAH1B1 PCM1 PCNT PLK1 CEP192 HAUS2 PPP2R1A PRKACA CEP72 CDK5RAP2 PRKAR2B CENPJ TUBBP2 TUBA4A TUBG1 LOC730418 WEE1 XPO1 YWHAE YWHAG ALMS1 TUBA1A CEP76 CEP290 CEP63 CEP70 OFD1 TUBGCP6 SSNA1 DYNLL1 CCNA2 CCNA1 CCNB1 CCNH PKMYT1 CCNB2 CEP41 CEP135 CEP57 CKAP5 CDK1 CDC25A CDC25B CDC25C +REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK PRKAG2 PRKAG3 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 RHEB TSC1 TSC2 +REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION NOD1 TAB1 MAPK14 TAB2 TAB3 IRAK1 IRAK2 MAPK11 MAP2K3 MAP2K6 NOD2 LOC650832 MAP3K7 TRAF6 MAPKAPK3 IKBKG RIPK2 MAPKAPK2 +REACTOME_DNA_REPAIR http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DNA_REPAIR RAD50 CDK7 CCNO MAD2L2 POLD3 ERCC8 ALKBH2 DDB1 DDB2 ERCC1 ERCC2 ERCC3 ERCC4 ERCC5 ERCC6 FANCA FANCC FANCD2 FANCE FANCB FANCF FANCG ALKBH3 FEN1 SMUG1 XRCC6 ZBTB32 UBE2T GTF2H1 GTF2H2 GTF2H3 GTF2H4 H2AFX APEX1 LOC389901 LIG1 LIG3 LIG4 MGMT MNAT1 MPG MRE11A MUTYH NBN ATM NTHL1 OGG1 PCNA REV1 POLB POLD1 POLD2 POLE POLE2 POLH POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L ATR FANCL TDP1 PRKDC XAB2 FANCM POLD4 RAD23B RAD51 RAD52 REV3L RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 RPS27A LOC648152 LOC651610 LOC651921 LOC652672 LOC652857 GTF2H2B BRCA1 BRCA2 TCEA1 TDG TP53BP1 RPS27AP11 UBA52 USP1 XPA XPC XRCC1 XRCC4 XRCC5 PALB2 C17orf70 BRIP1 MBD4 CCNH C19orf40 MDC1 +REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS RASGRP1 RASGRP2 MGLL DGKK DGKA DGKB DGKG DGKH DGKQ DAGLB ITPR2 ITPR3 PRKCD PRKCE PRKCH PRKCQ TRPC7 TRPC3 TRPC6 LOC730221 LOC730335 DAGLA DGKE DGKD DGKI +REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS CDK7 CDK9 SUPT16H ERCC2 ERCC3 NCBP2 COBRA1 GTF2A1 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 MNAT1 NCBP1 TH1L POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L TCEB1P3 LOC652857 GTF2H2B SSRP1 SUPT4H1 SUPT5H TAF1 TAF4 TAF4B TAF5 TAF6 TAF9 TAF10 TAF11 TAF12 TAF13 TBP TCEA1 TCEB1 TCEB2 TCEB3 WHSC2 RDBP ELL CCNH CCNT1 CCNT2 CTDP1 +REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS DAPK1 DAPK3 DCC UNC5B DAPK2 APPL1 CASP3 CASP9 UNC5A MAGED1 +REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION PIGK MUC12 PREB ALG3 B3GNT3 SEC24B SEC23A ST6GALNAC2 B3GNT2 MAN1A2 GALNT6 GALNT5 MAN1B1 MGAT4B MGAT4A GALNT13 GALNTL2 MUCL1 PIGU MUC17 MUC15 ALG10B B3GNTL1 ARSK DAD1 DDOST GALNTL5 DHPS DPAGT1 B3GNT6 EIF5A ALG14 F2 F7 F9 F10 DOLK SEC31A ARSG GANAB PIGN FUT8 ST6GALNAC3 MGAT4C SUMF2 GALNT1 GALNT2 GALNT3 GALNT8 GCNT1 GGCX B4GALT1 ST6GALNAC4 PIGW SUMF1 LOC285407 C1GALT1C1 PDIA3 ALG5 GMPPB GMPPA ALG6 ST8SIA6 ARSI ARSH STT3A GALNTL4 B3GNT8 MUC21 LMAN1 ARSA ARSB STS MAN1A1 MAN2A1 ARSE ARSF MGAT1 MGAT2 MGAT3 MGAT5 MPI ALG11 GALNTL6 MUC2 MUC4 MUC5AC MUC6 MUC7 FURIN GALNT9 ST8SIA3 SAR1B PIGP GCNT4 PIGT GALNT7 PGM3 PIGA PIGC PIGF PIGH PLAUR PMM1 PMM2 DPM3 PIGG PIGX GALNT10 PIGV EDEM2 UGGT2 ALG13 PRKCSH ALG1 PROC PROS1 EIF5A2 MUC13 UGGT1 C1GALT1 MAN1C1 DOLPP1 GALNTL1 MUC3B RPN1 RPN2 GALNT11 SEC13 WBSCR17 GCNT6 ST6GAL1 ST3GAL1 ST3GAL2 GNPNAT1 ST3GAL3 LOC652612 LOC652741 MUC5B MUC19 LOC732162 MOGS VKORC1 ALG8 ALG12 B3GNT4 GALNT14 ARSJ MANEA GALNT12 ALG9 TUSC3 SEMA6D PGAP1 EDEM3 CALR ST8SIA2 CANX DOHH B3GNT5 PIGO B3GNT9 ALG10 ALG2 B4GALT4 B4GALT3 B4GALT2 GPAA1 DPM1 DPM2 PROZ MCFD2 PIGQ RFT1 GCNT3 B3GNT7 PIGM B4GALT6 B4GALT5 PIGS MUC16 PIGL PIGB SEC24C EDEM1 MLEC SEC24D GFPT2 +REACTOME_CHROMOSOME_MAINTENANCE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CHROMOSOME_MAINTENANCE STAG1 SYCP2 CENPA POLD3 STAG3 STAG2 RUVBL2 DIDO1 OIP5 HIST4H4 HIST3H2BB DKC1 DNA2 FEN1 SYNE2 SYNE1 ITGB3BP POLA2 CENPI HIST1H2BA SUN2 POT1 TINF2 SMC1B HIST1H2AE HIST1H2AD H2AFX H2AFZ HIST1H2BD HIST1H2BB HSPA2 LIG1 LMNA LMNB1 CENPP LOC440577 NPM1 SYCP3 PCNA RSF1 MIS18A POLA1 POLD1 POLD2 POLE POLE2 TERF2IP ATR WRAP53 CENPQ MIS18BP1 HJURP HIST2H4B PRIM1 PRIM2 NHP2 CENPN TEX12 CASC5 POLD4 RAD21 RBBP4 RBBP7 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 CENPK RBBP4P1 LOC648152 CENPH ACD LOC651921 BRCA1 SYCP1 TERF1 TERF2 TERT HIST2H2AA4 UBE2I CENPO MLF1IP SMC1A HIST3H3 HIST1H4I HIST1H2AJ HIST1H2AC HIST1H2AB HIST2H2AA3 HIST2H2AC HIST1H2BG HIST1H2BL HIST1H2BN HIST1H2BM HIST1H2BF HIST1H2BE HIST1H2BH HIST1H2BI HIST1H2BC HIST1H2BO HIST2H2BE HIST1H4A HIST1H4D HIST1H4F HIST1H4K HIST1H4J HIST1H4C HIST1H4H HIST1H4B HIST1H4E HIST1H4L HIST2H4A SMARCA5 FKBP6 HIST1H2BK RUVBL1 HIST1H2BJ SMC3 REC8 +REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE CENPA OIP5 HIST4H4 HIST3H2BB ITGB3BP CENPI HIST1H2BA HIST1H2AE HIST1H2AD H2AFX H2AFZ HIST1H2BD HIST1H2BB CENPP LOC440577 NPM1 RSF1 MIS18A CENPQ MIS18BP1 HJURP HIST2H4B CENPN CASC5 RBBP4 RBBP7 CENPK RBBP4P1 CENPH HIST2H2AA4 CENPO MLF1IP HIST1H4I HIST1H2AJ HIST1H2AC HIST1H2AB HIST2H2AA3 HIST2H2AC HIST1H2BG HIST1H2BL HIST1H2BN HIST1H2BM HIST1H2BF HIST1H2BE HIST1H2BH HIST1H2BI HIST1H2BC HIST1H2BO HIST2H2BE HIST1H4A HIST1H4D HIST1H4F HIST1H4K HIST1H4J HIST1H4C HIST1H4H HIST1H4B HIST1H4E HIST1H4L HIST2H4A SMARCA5 HIST1H2BK RUVBL1 HIST1H2BJ +REACTOME_L1CAM_INTERACTIONS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_L1CAM_INTERACTIONS RANBP9 STIP1 AP2M1 AP2S1 CLTA CLTC CNTN1 CSNK2A1 CSNK2A2 CSNK2B NCAN AP2A1 AP2A2 AP2B1 DCX DLG1 DLG3 DNM1 DNM2 DPYSL2 EGFR ALCAM FGFR1 KIF4A CNTN6 RPS6KA6 LAMA1 KIF4B ANK1 ANK3 ITGA1 ITGA2 ITGA2B ITGA5 ITGA9 ITGAV ITGB1 ITGB3 KCNQ2 KCNQ3 L1CAM LAMB1 LAMC1 MSN NCAM1 NRCAM PAK1 SPTBN5 SCN3B MAPK1 MAPK3 MAP2K1 MAP2K2 KIAA1598 SPTBN4 RAC1 RDX RPS6KA1 RPS6KA2 RPS6KA3 SCN1B SCN2A SCN2B SCN4A SCN5A SCN7A SCN8A SDCBP SH3GL2 LOC650400 SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SRC CNTN2 LOC731231 EZR CNTNAP1 NUMB NRP2 NRP1 RPS6KA4 RPS6KA5 CD24 +REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING DCC PITPNA PLCG1 TRPC7 TRPC3 TRPC4 TRPC5 TRPC6 LOC730221 LOC730335 NTN1 +REACTOME_SIGNALING_BY_ILS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_ILS NOD1 TAB1 IRAK3 CHUK MAP3K8 CRK CRKL CSF2 CSF2RA CSF2RB PTK2B TAB2 PELI3 FYN TAB3 GRB2 RAPGEF1 BLNK HCK HGF HRAS IKBKB IL1A IL1B IL1R1 IL1RAP IL1RN IL2 IL2RA IL2RB IL2RG IL3 IL3RA IL5 IL5RA IL6 IL6R IL6ST IL7 IL7R IL18 INPPL1 IRAK1 IRAK2 JAK1 JAK2 JAK3 KRAS TMEM189-UBE2V1 LCK LYN MAP3K3 MYD88 NFKB2 NRAS IRAK4 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 TOLLIP PRKACB MAPK1 MAPK3 MAP2K1 MAP2K2 MAP2K6 PELI2 PELI1 PTPN6 RAF1 RELA NOD2 MAP2K4 SHC1 LOC649891 SKP1 SOS1 STAT1 STAT3 STAT5A STAT5B SYK MAP3K7 TEC TRAF6 TYK2 UBE2N VAV1 YES1 YWHAB YWHAZ IL1R2 TNIP2 CASP1 CUL1 PIK3R3 IKBKG CBL RIPK2 SQSTM1 BTRC SOCS3 CDK1 GAB2 RBX1 +REACTOME_NETRIN1_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NETRIN1_SIGNALING UNC5D HFE2 DCC DOCK1 UNC5B ABLIM3 FYN RGMB ABLIM1 MYO10 NCK1 NEO1 PITPNA PLCG1 PRKCQ RGMA TRPC7 PTK2 RAC1 NTN4 ROBO1 SIAH1 SIAH2 SLIT1 SLIT3 SRC TRIO TRPC3 TRPC4 TRPC5 TRPC6 LOC730030 LOC730221 LOC730335 EZR UNC5C WASL UNC5A SLIT2 NTN1 CDC42 +REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS MED6 ACOT8 MED16 COL4A3BP LPCAT3 CDK8 CEPT1 CDS1 PEMT YAP1 CDIPT SLC25A17 NCOA2 AGPAT1 AGPAT2 SPTLC1 SLCO1B1 PMVK EBP CETP CGA NEU3 CYP46A1 PPARGC1A SLC27A5 SLC27A2 GLIPR1 CHAT AKR1C4 PLA2G16 CHKA CHKB MED8 MGLL APOA5 CYP2R1 CLPS PLD4 PLIN2 DEGS2 ACER1 SLC44A3 MBOAT2 NEU4 SGPP2 PPARGC1B STARD4 CPT1A CPT1B CPT2 AGPAT6 CRAT CREBBP CSNK1G2 PIK3R6 STARD6 CTGF GPAT2 PPM1L ARSK MBOAT1 CYP1A1 CYP4A11 CYP7A1 CYP8B1 CYP11A1 CYP11B1 CYP11B2 CYP17A1 CYP19A1 CYP21A2 CYP24A1 CYP27A1 CYP27B1 CYP51A1 PHOSPHO1 ECI1 DECR1 SGMS2 DHCR7 DHCR24 AGT ECHS1 ABCA1 A2M PIKFYVE PLD6 EP300 CERS3 SLC44A5 ESRRA ALAS1 ALB ABCD1 FABP4 FABP1 FABP6 ACSL1 ACSL3 ACSL4 FASN MED19 FDFT1 FDPS FHL2 ARSG SACM1L NCOA6 CDK19 AKR1B1 GPD1L LPIN1 ACSL6 SIN3B MED13L PIP5K1C SLC44A1 PIK3R5 AMACR PLD3 PITPNB KDSR LCLAT1 CERS6 LPCAT4 PLA2G4F GALC SUMF2 SGMS1 WWTR1 SIN3A HACL1 LDLRAP1 TIAM2 PLA2G2D GBA GC ANKRD1 GK INPP5J GLA GLB1 TNFRSF21 GM2A GPD1 GPD2 SLCO1B3 PLA2G4D SUMF1 MED4 GRHL1 CERS2 ACAA1 HADHA HADHB HADH HEXA HEXB PLA2G2E PIK3R4 ACACA HMGCL HMGCR HMGCS1 HMGCS2 ACACB HSD3B1 HSD3B2 HSD11B1 HSD17B1 HSD17B3 HSD17B4 ACADL HSPG2 APOA1 APOA2 APOB ENPP7 ACADM ARSI ACER2 IDH1 IDI1 APOC2 APOC3 ARSH APOE ACADS INPPL1 ACADVL ARF1 SLC27A1 ARF3 ACAT1 LBR LCAT LDLR LHB LIPC LIPE FADS1 MED11 LPA LPL LRP2 LSS ARNTL ARSA ARSB STS ARSE ARSF ME1 ASAH1 ACHE MTM1 MTTP MUT MVD MVK ACLY NEU1 NEU2 NFYA NFYB NPAS2 NRF1 OCRL OSBP OXCT1 P4HB G0S2 PLA2G3 PNPLA8 NSDHL PCCA PCCB ACOX1 MED31 ABHD5 RDH11 SAR1B ANGPTL4 HSD17B12 PCYT1A CYP39A1 PRKAG2 HSD17B7 MED15 ACSL5 INPP5K ABCB4 PHYH PIK3C2A PIK3C2B PIK3C2G PIK3C3 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PI4KA PI4KB PIP4K2A PLA2G1B PLA2G2A PLA2G4A PLA2G5 PLD1 PLD2 PLIN1 PLTP BCMO1 PNLIP PNLIPRP2 POMC UGT1A9 PPARA CRLS1 CROT PPARG MED1 CTSA MED18 ELOVL2 LPCAT2 PPP1CA PPP1CB PPP1CC MED9 ETNK2 PI4K2B AGPAT5 ACER3 PI4K2A ETNK1 SMPD3 MED29 SMPD4 PRKAA2 PRKAB2 PRKACA PRKACB PRKACG VAC14 FAR2 PRKD1 GPCPD1 LGMN PSAP INPP5E ASAH2 SPHK2 AGPAT3 AGPAT4 CHPT1 BAAT PNPLA2 SLC44A2 PTEN GPAM GBA2 GBA3 TRIB3 PCYT2 RBP2 ELOVL5 RORA BDH1 RXRA MSMO1 SC5DL SCP2 SDC1 ABCG5 ABCG8 ABCD1P5 MTMR14 PLA2G2F CERK ELOVL1 BMP1 LPIN3 LOC651621 ASAH2C SLC10A1 SLC10A2 SLC25A1 SLCO1A2 SMARCD3 SMPD1 SMPD2 SQLE SRD5A1 SRD5A2 AKR1D1 SREBF1 SREBF2 STAR ELOVL4 SULT2A1 MED22 TAZ TBL1X TEAD1 TEAD4 TEAD3 TM7SF2 LOC729155 TXNRD1 LOC730412 LOC730418 LOC731292 UGCG SLC25A20 ELOVL6 MBOAT7 CERS4 ARSJ SRD5A3 TBL1XR1 PLBD1 LPCAT1 ELOVL7 HSD3B7 CUBN PNPLA3 SLC44A4 STARD5 PTDSS2 SGPP1 PLA2G12A AMN MED25 NCOA3 ACOX2 ACOX3 ELOVL3 PIP5K1B PIP4K2B PLA2G6 PLA2G10 FAR1 MED10 GNPAT TEAD2 DGAT2 MCEE AGPAT9 PIK3R3 AGPS PRIC285 EPT1 DEGS1 CAV1 PLA2G4C PPAP2A PPAP2C PPAP2B ABCB11 NCOA1 DGAT1 ABCC3 CDS2 MTMR1 PEX11A INPP4B HDAC3 SYNJ1 SYNJ2 SPHK1 SGPL1 MTMR3 MTMR2 CCNC CH25H MED30 CERS5 MTMR6 MTMR7 MTMR4 IDI2 VAPB VAPA LRAT MED14 TPTE2 MED21 FADS2 CYP7B1 MED23 MED17 MED26 MED27 MED7 GGPS1 PCYT1B MED20 CD36 PGS1 SCARB1 GAL3ST1 SPTLC2 TECR NR1D1 CLOCK NCOR1 NCOR2 ABCG1 LPIN2 TGS1 PTDSS1 MED24 FIG4 LPGAT1 MED12 +REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS ANK1 ANK3 KCNQ2 KCNQ3 L1CAM NRCAM SPTBN5 SCN3B SPTBN4 SCN1B SCN2A SCN2B SCN4A SCN5A SCN7A SCN8A LOC650400 SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 LOC731231 +REACTOME_SIGNAL_TRANSDUCTION_BY_L1 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNAL_TRANSDUCTION_BY_L1 AP2M1 AP2S1 CLTA CLTC CSNK2A1 CSNK2A2 CSNK2B AP2A1 AP2A2 AP2B1 EGFR FGFR1 RPS6KA6 ITGA2B ITGA5 ITGA9 ITGAV ITGB1 ITGB3 L1CAM NCAM1 PAK1 MAPK1 MAPK3 MAP2K1 MAP2K2 RAC1 RPS6KA1 RPS6KA2 RPS6KA3 SH3GL2 NRP1 RPS6KA4 RPS6KA5 +REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM MED6 MED16 CDK8 YAP1 NCOA2 AGPAT1 AGPAT2 PPARGC1A GLIPR1 MED8 APOA5 PLIN2 PPARGC1B CPT1A CPT1B CPT2 AGPAT6 CREBBP CTGF GPAT2 CYP1A1 CYP4A11 CYP7A1 ECI1 DECR1 AGT ECHS1 ABCA1 EP300 ESRRA ALAS1 FABP1 ACSL1 ACSL3 ACSL4 FASN MED19 FDFT1 FHL2 NCOA6 CDK19 GPD1L LPIN1 ACSL6 SIN3B MED13L LCLAT1 LPCAT4 WWTR1 SIN3A TIAM2 ANKRD1 GK TNFRSF21 GPD1 GPD2 MED4 GRHL1 HADHA HADHB HADH ACACA HMGCL HMGCR HMGCS1 HMGCS2 ACACB ACADL APOA1 APOA2 ACADM ACADS ACADVL SLC27A1 ACAT1 FADS1 MED11 ARNTL ME1 MUT ACLY NFYA NFYB NPAS2 NRF1 OXCT1 G0S2 PCCA PCCB ACOX1 MED31 ANGPTL4 HSD17B12 PRKAG2 MED15 ACSL5 ABCB4 UGT1A9 PPARA PPARG MED1 MED18 ELOVL2 MED9 AGPAT5 MED29 PRKAA2 PRKAB2 AGPAT3 AGPAT4 GPAM TRIB3 ELOVL5 RORA BDH1 RXRA ELOVL1 LPIN3 SLC25A1 SMARCD3 SREBF1 SREBF2 ELOVL4 SULT2A1 MED22 TBL1X TEAD1 TEAD4 TEAD3 TXNRD1 SLC25A20 ELOVL6 TBL1XR1 LPCAT1 ELOVL7 MED25 NCOA3 ELOVL3 MED10 TEAD2 DGAT2 MCEE AGPAT9 PRIC285 NCOA1 DGAT1 PEX11A HDAC3 CCNC MED30 MED14 MED21 MED23 MED17 MED26 MED27 MED7 MED20 CD36 TECR NR1D1 CLOCK NCOR1 NCOR2 LPIN2 TGS1 MED24 MED12 +REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES SLC35A1 SLCO1B1 SLC27A4 SLC35D2 SLCO2B1 SLC29A1 ALB SLC29A4 SLC35D1 SLC35A3 SLCO4A1 SLCO3A1 SLCO1B3 SLC27A6 SLC29A2 SLC35B2 SLCO4C1 SLC27A1 SLCO1C1 AVP SLC29A3 SLC35C1 SLC28A3 SLCO2A1 SLCO1A2 SLC35A2 SLC35B4 SLC5A6 SLC28A2 SLC28A1 SLC33A1 +REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS CHRNA1 CHRNA2 CHRNA3 CHRNA4 CHRNA5 CHRNA7 CHRNB2 CHRNB3 CHRNB4 CHRNA9 LOC732445 CHRNA6 CHRFAM7A +REACTOME_RNA_POL_I_PROMOTER_OPENING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_I_PROMOTER_OPENING HIST4H4 HIST2H3C HIST3H2BB HIST1H2BA HIST1H2AE HIST1H2AD H2AFX H2AFZ HIST1H2BD HIST1H2BB H3F3A H3F3B HIST2H3A H3F3AP5 HIST2H4B MAPK3 H3F3AP6 HIST2H3D HIST2H2AA4 LOC731820 UBTF HIST1H4I HIST1H2AJ HIST1H2AC HIST1H2AB HIST2H2AA3 HIST2H2AC HIST1H2BG HIST1H2BL HIST1H2BN HIST1H2BM HIST1H2BF HIST1H2BE HIST1H2BH HIST1H2BI HIST1H2BC HIST1H2BO HIST2H2BE HIST1H3A HIST1H3D HIST1H3C HIST1H3E HIST1H3I HIST1H3G HIST1H3J HIST1H3H HIST1H3B HIST1H4A HIST1H4D HIST1H4F HIST1H4K HIST1H4J HIST1H4C HIST1H4H HIST1H4B HIST1H4E HIST1H4L HIST2H4A HIST1H2BK MBD2 HIST1H3F HIST1H2BJ +REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS CHRNA1 CHRNA2 CHRNA3 CHRNA4 CHRNA5 CHRNB2 CHRNB3 CHRNB4 CHRND CHRNE CHRNG CHRNA6 +REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT SLC22A7 SLC22A12 SLC22A18 SLC22A15 SLC22A11 SLC22A1 SLC22A3 SLC22A2 SLC22A4 SLC22A5 SLC22A16 SLC22A6 SLC22A8 +REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING DCC DOCK1 ABLIM3 FYN ABLIM1 NCK1 PTK2 RAC1 SRC TRIO WASL NTN1 CDC42 +REACTOME_RECYCLING_PATHWAY_OF_L1 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RECYCLING_PATHWAY_OF_L1 AP2M1 AP2S1 CLTA CLTC AP2A1 AP2A2 AP2B1 DNM1 DNM2 DPYSL2 KIF4A RPS6KA6 KIF4B L1CAM MSN MAPK1 KIAA1598 RDX RPS6KA1 RPS6KA2 RPS6KA3 SH3GL2 SRC EZR NUMB RPS6KA4 RPS6KA5 +REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS DOLK ALG5 GMPPB GMPPA MPI PGM3 PMM1 PMM2 DPM3 DOLPP1 GNPNAT1 DPM1 DPM2 GFPT2 +REACTOME_RESPIRATORY_ELECTRON_TRANSPORT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RESPIRATORY_ELECTRON_TRANSPORT UQCR11 NDUFA11 COX4I1 COX5B COX6A1 COX6B1 COX6C COX7B COX7C COX8A CYC1 ETFA ETFB ETFDH UQCRQ NDUFS7 UQCRHL COX1 COX2 COX3 CYTB ND1 ND2 ND3 ND4 ND4L ND5 ND6 NDUFA1 NDUFA2 NDUFA3 NDUFA4 NDUFA5 NDUFA6 NDUFA7 NDUFA8 NDUFA9 NDUFA10 NDUFAB1 NDUFB1 NDUFB2 NDUFB3 NDUFB4 NDUFB5 NDUFB6 NDUFB7 NDUFB8 NDUFB9 NDUFB10 NDUFC1 NDUFC2 NDUFS1 NDUFS2 NDUFS3 NDUFV1 NDUFS4 NDUFS5 NDUFS6 NDUFS8 NDUFV2 NDUFV3 NDUFA13 CYCS NDUFA12 SDHA SDHB SDHC SDHD MTND5P10 UQCRBP1 LOC651820 LOC727947 UQCRB UQCRC1 UQCRC2 UQCRFS1 UQCRH COX7A2L COX5A +REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION PREB ALG3 SEC24B SEC23A MAN1A2 MAN1B1 MGAT4B MGAT4A ALG10B DAD1 DDOST DPAGT1 ALG14 DOLK SEC31A GANAB FUT8 MGAT4C B4GALT1 LOC285407 PDIA3 ALG5 GMPPB GMPPA ALG6 ST8SIA6 STT3A LMAN1 MAN1A1 MAN2A1 MGAT1 MGAT2 MGAT3 MGAT5 MPI ALG11 ST8SIA3 SAR1B PGM3 PMM1 PMM2 DPM3 EDEM2 UGGT2 ALG13 PRKCSH ALG1 UGGT1 MAN1C1 DOLPP1 RPN1 RPN2 SEC13 ST6GAL1 GNPNAT1 MOGS ALG8 ALG12 MANEA ALG9 TUSC3 EDEM3 CALR ST8SIA2 CANX ALG10 ALG2 B4GALT4 B4GALT3 B4GALT2 DPM1 DPM2 MCFD2 RFT1 B4GALT6 B4GALT5 SEC24C EDEM1 MLEC SEC24D GFPT2 +REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX PSMD14 PSMA8 E2F1 E2F2 E2F3 PSME4 ORC6 ORC3 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 ORC1 ORC2 ORC4 ORC5 GMNN PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RPS27A LOC652826 RPS27AP11 UBA52 CDT1 MCM8 PSMF1 PSMD6 CDC6 +REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN ALG3 ALG10B DPAGT1 ALG14 DOLK LOC285407 ALG5 GMPPB GMPPA ALG6 MPI ALG11 PGM3 PMM1 PMM2 DPM3 ALG13 ALG1 DOLPP1 GNPNAT1 ALG8 ALG12 ALG9 ALG10 ALG2 DPM1 DPM2 RFT1 GFPT2 +REACTOME_IL1_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IL1_SIGNALING NOD1 TAB1 IRAK3 CHUK MAP3K8 TAB2 PELI3 TAB3 IKBKB IL1A IL1B IL1R1 IL1RAP IL1RN IRAK1 IRAK2 TMEM189-UBE2V1 MAP3K3 MYD88 IRAK4 TOLLIP MAP2K1 MAP2K6 PELI2 PELI1 NOD2 MAP2K4 SKP1 MAP3K7 TRAF6 UBE2N IL1R2 TNIP2 CUL1 IKBKG RIPK2 SQSTM1 BTRC RBX1 +REACTOME_GLOBAL_GENOMIC_NER_GG_NER http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLOBAL_GENOMIC_NER_GG_NER CDK7 POLD3 DDB1 DDB2 ERCC1 ERCC2 ERCC3 ERCC4 ERCC5 GTF2H1 GTF2H2 GTF2H3 GTF2H4 LIG1 MNAT1 PCNA POLD1 POLD2 POLE POLE2 POLD4 RAD23B RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 LOC652672 LOC652857 GTF2H2B XPA XPC CCNH +REACTOME_CGMP_EFFECTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CGMP_EFFECTS KCNMB2 MRVI1 PDE10A KCNMB3 KCNMB4 KCNMB1 PDE11A PDE1A PDE2A PDE3A PDE3B PDE6A PDE6G PDE9A PDE1B PDE6B PRKG1 PRKG2 PDE5A +REACTOME_REGULATION_OF_SIGNALING_BY_CBL http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_SIGNALING_BY_CBL CRK CRKL FYN GRB2 RAPGEF1 BLNK HCK LYN PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 SYK VAV1 YES1 PIK3R3 CBL +REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION PHGDH GLS2 GLS GLUD1 GLUL GOT1 GOT2 GPT PSAT1 ASNS OAT PSPH PYCR1 ALDH18A1 LOC643554 GPT2 CCBL1 +REACTOME_CALNEXIN_CALRETICULIN_CYCLE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CALNEXIN_CALRETICULIN_CYCLE MAN1B1 GANAB PDIA3 EDEM2 UGGT2 PRKCSH UGGT1 EDEM3 CALR CANX EDEM1 +REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP GPR119 DPP4 SEC11A GATA4 GIP FFAR1 SPCS1 ISL1 PAX6 PCSK1 SPCS3 LOC653566 SEC11C SPCS2 +REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS AQP8 AQP1 AQP2 AQP3 AQP4 AQP5 AQP6 AQP7 AQP9 MIP AQP10 +REACTOME_NEPHRIN_INTERACTIONS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEPHRIN_INTERACTIONS CD2AP FYN NCK1 NPHS1 PIK3CA PIK3CB PIK3R1 PIK3R2 SPTAN1 SPTBN1 LOC729030 ACTN4 KIRREL2 NCK2 KIRREL3 ACTN1 ACTN2 IQGAP1 WASL MAGI2 +REACTOME_IL_3_5_AND_GM_CSF_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IL_3_5_AND_GM_CSF_SIGNALING CRK CRKL CSF2 CSF2RA CSF2RB FYN GRB2 RAPGEF1 BLNK HCK HRAS IL2 IL2RA IL2RB IL2RG IL3 IL3RA IL5 IL5RA INPPL1 JAK1 JAK2 JAK3 LYN PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PRKACB PTPN6 SHC1 SOS1 STAT5A STAT5B SYK TEC VAV1 YES1 YWHAZ PIK3R3 CBL GAB2 +REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE KCNMB2 MRVI1 PDE10A KCNMB3 KCNMB4 GUCY1A2 GUCY1A3 GUCY1B3 KCNMB1 NOS1 NOS2 NOS3 PDE11A PDE1A PDE2A PDE3A PDE3B PDE6A PDE6G PDE9A PDE1B PDE6B PRKG1 PRKG2 PDE5A +REACTOME_PLATELET_HOMEOSTASIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PLATELET_HOMEOSTASIS KCNMB2 MRVI1 GNB5 PDE10A MAPK14 FGR KCNMB3 KCNMB4 GNAS GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GUCY1A2 GUCY1A3 GUCY1B3 APOB ITPR2 ITPR3 KCNMB1 NOS1 NOS2 NOS3 ATP2A1 ATP2A2 ATP2A3 ATP2B2 ATP2B3 P2RX1 PDE11A PDE1A PDE2A PDE3A PDE3B PDE6A PDE6G PDE9A PDE1B PDE6B PECAM1 GNG13 PLA2G4A GNG2 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRKG1 PRKG2 GNG12 TRPC7 PTGIR PTPN6 GNB4 SLC8A2 SLC8A1 SLC8A3 STIM1 TRPC3 TRPC6 LOC730221 LOC730335 LRP8 ORAI1 PDE5A GNG8 +REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE MAN1B1 GANAB PDIA3 EDEM2 UGGT2 PRKCSH UGGT1 MOGS EDEM3 CALR CANX EDEM1 MLEC +REACTOME_PLATELET_SENSITIZATION_BY_LDL http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PLATELET_SENSITIZATION_BY_LDL MAPK14 FGR APOB PECAM1 PLA2G4A PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PTPN6 LRP8 +REACTOME_AQUAPORIN_MEDIATED_TRANSPORT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AQUAPORIN_MEDIATED_TRANSPORT GNB5 ADCY1 ADCY2 ADCY3 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADCY4 RAB11FIP2 GNAS GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 AQP8 AQP1 AQP2 AQP3 AQP4 AQP5 AQP6 AQP7 AQP9 MIP MYO5B GNG13 GNG2 AVP AVPR2 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B GNG12 GNB4 LOC730418 RAB11A AQP10 GNG8 +REACTOME_IL_RECEPTOR_SHC_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IL_RECEPTOR_SHC_SIGNALING CSF2 CSF2RA CSF2RB GRB2 HRAS IL2 IL2RA IL2RB IL2RG IL3 IL3RA IL5 IL5RA INPPL1 JAK1 JAK2 JAK3 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PTPN6 SHC1 SOS1 PIK3R3 GAB2 +REACTOME_RAP1_SIGNALLING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RAP1_SIGNALLING RASGRP1 RASGRP2 RAPGEF3 RAPGEF4 RAP1GAP2 PRKACA PRKACB PRKACG PRKG1 RAF1 RAP1A RAP1B RAP1GAP SIPA1 LOC730418 YWHAB YWHAZ +REACTOME_PLATELET_CALCIUM_HOMEOSTASIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PLATELET_CALCIUM_HOMEOSTASIS ITPR2 ITPR3 ATP2A1 ATP2A2 ATP2A3 ATP2B2 ATP2B3 P2RX1 TRPC7 SLC8A2 SLC8A1 SLC8A3 STIM1 TRPC3 TRPC6 LOC730221 LOC730335 ORAI1 +REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS SIRPB1 SIRPA PTK2B FYB GRB2 SIRPG PTK2 PTPN6 SRC TYROBP SKAP2 CD47 +REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR GNB5 GNAS GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GNG13 GNG2 GNG12 PTGIR GNB4 GNG8 +REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION SLC32A1 ABAT RIMS1 GAD1 GAD2 HSPA8 RAB3A SLC6A1 SLC6A11 SLC6A12 SNAP25 STX1A STXBP1 VAMP2 SYT1 ALDH5A1 DNAJC5 +REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION CDX2 GPR119 CTNNB1 DPP4 SEC11A GATA4 GCG GIP GNB3 FFAR1 SPCS1 GRP O3FAR1 ISL1 LEP PAX6 PCSK1 GNG13 SPCS3 LOC653566 SEC11C SPCS2 +REACTOME_TRANSPORT_OF_ORGANIC_ANIONS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSPORT_OF_ORGANIC_ANIONS SLCO1B1 SLCO2B1 ALB SLCO4A1 SLCO3A1 SLCO1B3 SLCO4C1 SLCO1C1 AVP SLCO2A1 SLCO1A2 +REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 CDX2 GPR119 CTNNB1 DPP4 SEC11A GCG GNB3 FFAR1 SPCS1 GRP O3FAR1 LEP PAX6 PCSK1 GNG13 SPCS3 LOC653566 SEC11C SPCS2 +REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS GNB5 ADCY1 ADCY2 ADCY3 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADCY4 RAB11FIP2 GNAS GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 AQP1 AQP2 AQP3 AQP4 MYO5B GNG13 GNG2 AVP AVPR2 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B GNG12 GNB4 LOC730418 RAB11A GNG8 +REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 EXOSC8 EXOSC6 DCP2 AKT1 DIS3 EXOSC7 EXOSC2 EXOSC3 EXOSC1 EXOSC9 XRN1 EXOSC4 DCP1A EXOSC5 ZFP36L1 YWHAB MAPKAPK2 +REACTOME_IRAK1_RECRUITS_IKK_COMPLEX http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IRAK1_RECRUITS_IKK_COMPLEX CHUK PELI3 IKBKB IRAK1 TMEM189-UBE2V1 PELI2 PELI1 TRAF6 UBE2N IKBKG +REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION TANK CREBBP EP300 DDX58 TBK1 IFNA1 IFNA2 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNA10 IFNA14 IFNA16 IFNA17 IFNA21 IFNB1 IRF1 IRF2 IRF3 IRF7 MAVS IFIH1 TRAF2 TRAF6 TRIM25 SIKE1 RNF135 IKBKE +REACTOME_CIRCADIAN_CLOCK http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CIRCADIAN_CLOCK NAMPT NCOA2 PPARGC1A CPT1A CREB1 ATF2 CREBBP CRY1 CRY2 CSNK1D CSNK1E DBP EP300 F7 NCOA6 CCRN4L FBXL3 NR3C1 HIF1A ARNTL MEF2C MEF2D NPAS2 SERPINE1 PER1 PPARA MED1 AVP ARNTL2 RORA RPS27A RXRA SKP1 SMARCD3 SREBF1 TBL1X RPS27AP11 UBA52 BHLHE41 TBL1XR1 NCOA3 ELOVL3 CUL1 PRIC285 BHLHE40 NCOA1 HDAC3 PER2 BTRC NR1D1 CLOCK NCOR1 TGS1 +REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION CHUK AGER DDX58 HMGB1 APP IKBKB MAP3K1 NFKB2 NFKBIA NFKBIB MAVS RELA S100A12 S100B SAA1 IFIH1 TRAF2 TRAF6 TRIM25 RNF135 IKBKG +REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION SH2B3 KIF20A CDK2 CDK5 HMG20B SH2B2 EHD1 KIF2C AKAP10 VPS45 HIST2H3C CREBBP GATA5 KLC3 ZFPM1 DOCK1 DOCK2 DOCK3 EP300 JMJD1C KIFAP3 KDM1A RCOR1 DOCK9 ZFPM2 CBX5 MAFF KIF4A ABL1 SIN3A SH2B1 KIF26A GATA1 GATA2 GATA3 GATA4 GATA6 KIF4B RACGAP1 H3F3A H3F3B HBB HBD HBE1 HBG2 HDAC1 HDAC2 EHD2 HIST2H3A IFNA1 IFNA2 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNA10 IFNA14 IFNA16 IFNA17 IFNA21 IFNB1 H3F3AP5 IRF1 IRF2 IRF3 IRF7 ITPK1 JAK2 KIF2A KIF3C KIF5A KIF5B KLC1 KIF11 KIFC1 KIF22 MAFG LOC441511 MYB NFE2 AK3 DOCK10 PRKACA MFN1 PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B KIF15 DOCK6 RAB5A RAC1 RAD51C RAD51B ZFYVE20 KIF9 H3F3AP6 KLC2 HIST2H3D TP53 LOC730418 LOC731820 WEE1 MAFK DOCK5 AKAP1 DOCK8 CABLES2 KIF18A CAPZA1 CAPZA2 HIST1H3A HIST1H3D HIST1H3C HIST1H3E HIST1H3I HIST1H3G HIST1H3J HIST1H3H HIST1H3B KIF2B HIST1H3F KLC4 CABLES1 KIF3B KIF23 DOCK4 MFN2 CDC42 +REACTOME_REGULATION_OF_IFNG_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_IFNG_SIGNALING IFNG IFNGR1 IFNGR2 JAK1 JAK2 PTPN1 PTPN2 PTPN6 LOC646981 STAT1 SUMO1 PIAS1 SOCS1 SOCS3 +REACTOME_GABA_A_RECEPTOR_ACTIVATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GABA_A_RECEPTOR_ACTIVATION ARHGEF9 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRG2 GABRG3 +REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS PSMD14 EXOSC8 EXOSC6 MAPK14 PSMA8 DCP2 EIF4G1 ELAVL1 AKT1 DIS3 EXOSC7 PSME4 EXOSC2 PABPC1 HNRNPD HSPA1B HSPA8 HSPB1 TNPO1 PARN EXOSC3 EXOSC1 EXOSC9 XRN1 EXOSC4 PRKCA PRKCD DCP1A MAPK11 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 EXOSC5 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RPS27A LOC652607 LOC652826 ZFP36L1 RPS27AP11 UBA52 XPO1 YWHAB YWHAZ ZFP36 NUP214 ANP32A KHSRP TNFSF13 MAPKAPK2 PSMF1 PSMD6 +REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS GABBR1 GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNGT1 GNGT2 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6 KCNJ9 KCNJ10 KCNJ12 KCNJ15 KCNJ16 GNG2 GNG12 GNG8 GABBR2 +REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION TAB1 TAB2 TAB3 IRAK2 RPS27A MAP3K7 TRAF6 RPS27AP11 UBA52 +REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION NOD1 TAB1 CHUK CREB1 ATF2 MAPK14 AGER DUSP3 DUSP4 DUSP6 DUSP7 ELK1 TAB2 FOS PELI3 TAB3 HMGB1 APP IKBKB IRAK1 IRAK2 JUN TMEM189-UBE2V1 MEF2A MEF2C MAP3K1 MYD88 ATF1 NFKB2 NFKBIA NFKBIB IRAK4 TLR7 ECSIT TLR8 TLR9 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D MAPK1 MAPK3 MAPK7 MAPK8 MAPK11 MAPK9 MAPK10 MAP2K1 MAP2K2 MAP2K3 MAP2K6 MAP2K7 PELI2 PELI1 RELA RPS6KA1 RPS6KA2 RPS6KA3 RPS27A S100A12 S100B SAA1 NOD2 MAP2K4 LOC650832 MAP3K7 TRAF6 RPS27AP11 UBA52 UBE2N MAPKAPK3 IKBKG RIPK2 RPS6KA5 MAPKAPK2 CDK1 +REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY CREBBP EP300 DDX58 TBK1 IFNB1 IRF3 IRF7 MAVS IFIH1 TRAF3 TRIM25 SIKE1 RNF135 IKBKE +REACTOME_GABA_B_RECEPTOR_ACTIVATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GABA_B_RECEPTOR_ACTIVATION ADCY1 ADCY2 ADCY3 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADCY4 GABBR1 GNAI1 GNAI2 GNAI3 GNAL GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNGT1 GNGT2 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6 KCNJ9 KCNJ10 KCNJ12 KCNJ15 KCNJ16 GNG2 GNG12 GNG8 GABBR2 +REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 CHUK DDX58 IKBKB MAVS IFIH1 TRIM25 CASP8 RNF135 CASP10 IKBKG RIPK1 FADD +REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP EXOSC8 EXOSC6 MAPK14 DCP2 AKT1 DIS3 EXOSC7 EXOSC2 PARN EXOSC3 EXOSC1 EXOSC9 EXOSC4 MAPK11 EXOSC5 YWHAZ KHSRP +REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION PREB SEC24B SEC23A MAN1A2 MGAT4B MGAT4A SEC31A FUT8 MGAT4C B4GALT1 ST8SIA6 LMAN1 MAN1A1 MAN2A1 MGAT1 MGAT2 MGAT3 MGAT5 ST8SIA3 SAR1B MAN1C1 SEC13 ST6GAL1 MANEA ST8SIA2 B4GALT4 B4GALT3 B4GALT2 MCFD2 B4GALT6 B4GALT5 SEC24C SEC24D +REACTOME_IRON_UPTAKE_AND_TRANSPORT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IRON_UPTAKE_AND_TRANSPORT TCIRG1 SLC46A1 ATP6V1G3 CP ATP6V0A2 ATP6V0D2 ATP6V1C2 FTH1 FTL FLVCR1 SLC40A1 HMOX1 HMOX2 ATP6V0A4 ATP6V1D ATP6V1H ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V0C ATP6V1C1 ATP6V1E1 ATP6V0B ATP6V1G2 STEAP3 MCOLN1 TF TFRC CYBRD1 ATP6V0E1 ATP6V1E2 ATP6V0D1 ATP6V1F ABCG2 ATP6V1G1 HEPH +REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP EXOSC8 EXOSC6 DCP2 DIS3 EXOSC7 EXOSC2 TNPO1 EXOSC3 EXOSC1 EXOSC9 XRN1 EXOSC4 DCP1A EXOSC5 YWHAB ZFP36 MAPKAPK2 +REACTOME_INTERFERON_GAMMA_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTERFERON_GAMMA_SIGNALING IRF9 GBP4 GBP5 GBP6 FCGR1A FCGR1B GBP1 GBP2 HLA-A HLA-B HLA-C HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DRB1 HLA-DRB3 HLA-DRB5 HLA-F HLA-G ICAM1 IRF8 IFNG IFNGR1 IFNGR2 IRF1 IRF2 IRF3 IRF4 IRF5 IRF6 IRF7 JAK1 JAK2 GBP7 CIITA LOC441019 MT2A NCAM1 OAS1 OAS2 OAS3 PML PRKCD B2M PTAFR PTPN1 PTPN2 PTPN6 LOC646981 HLA-K SP100 STAT1 SUMO1 VCAM1 CAMK2A CAMK2B CAMK2D PIAS1 OASL SOCS1 SOCS3 CD44 +REACTOME_N_GLYCAN_ANTENNAE_ELONGATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_N_GLYCAN_ANTENNAE_ELONGATION MGAT4B MGAT4A MGAT4C B4GALT1 ST8SIA6 MGAT5 ST8SIA3 ST6GAL1 ST8SIA2 B4GALT4 B4GALT3 B4GALT2 B4GALT6 B4GALT5 +REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING IRAK1 IRF7 TMEM189-UBE2V1 MYD88 IRAK4 TLR7 TLR8 TLR9 TRAF6 UBE2N +REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON TICAM1 LY96 TBK1 TICAM2 IRF3 IRF7 RPS27A TLR3 TLR4 TRAF3 RPS27AP11 UBA52 CD14 IKBKE +REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES ATP9A ATP8A1 ATP8B3 ATP10B ATP11B ATP11A ATP2C1 ATP11C ATP9B ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4 ATP1B1 ATP1B2 ATP1B3 FXYD2 ATP2A1 ATP2A2 ATP2A3 ATP2B2 ATP2B3 ATP4A ATP4B ATP8A2 ATP8B1 ATP7A ATP7B ATP10A ATP10D LOC644732 ATP8B4 ATP2C2 +REACTOME_INTERFERON_ALPHA_BETA_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTERFERON_ALPHA_BETA_SIGNALING ADAR IRF9 IFITM3 IFITM2 USP18 LOC144383 EGR1 IFI6 GBP2 HLA-A HLA-B HLA-C HLA-F HLA-G IRF8 IFI27 IFI35 IFIT2 IFIT1 IFIT3 IFNA1 IFNA2 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNA10 IFNA14 IFNA16 IFNA17 IFNA21 IFNAR1 IFNAR2 IFNB1 IRF1 IRF2 IRF3 IRF4 IRF5 IRF6 IRF7 ISG20 JAK1 MX1 MX2 OAS1 OAS2 OAS3 IP6K2 XAF1 PSMB8 PTPN1 PTPN6 RNASEL HLA-K STAT1 STAT2 TYK2 IFITM1 OASL SOCS1 SOCS3 ISG15 +REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING DDOST AGER HMGB1 APP LGALS3 PRKCSH MAPK1 MAPK3 S100A12 S100B SAA1 CAPZA1 CAPZA2 +REACTOME_GABA_RECEPTOR_ACTIVATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GABA_RECEPTOR_ACTIVATION ADCY1 ADCY2 ADCY3 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADCY4 ARHGEF9 GABBR1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRG2 GABRG3 GABRR1 GABRR2 GNAI1 GNAI2 GNAI3 GNAL GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNGT1 GNGT2 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6 KCNJ9 KCNJ10 KCNJ12 KCNJ15 KCNJ16 GNG2 GNG12 GNG8 GABBR2 +REACTOME_KINESINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_KINESINS KIF20A KIF2C KLC3 KIFAP3 KIF4A KIF26A KIF4B RACGAP1 KIF2A KIF3C KIF5A KIF5B KLC1 KIF11 KIFC1 KIF22 KIF15 KIF9 KLC2 KIF18A KIF2B KLC4 KIF3B KIF23 +REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI MGAT4B MGAT4A FUT8 MGAT4C B4GALT1 ST8SIA6 MAN2A1 MGAT2 MGAT3 MGAT5 ST8SIA3 ST6GAL1 ST8SIA2 B4GALT4 B4GALT3 B4GALT2 B4GALT6 B4GALT5 +REACTOME_REGULATION_OF_IFNA_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_IFNA_SIGNALING USP18 IFNA1 IFNA2 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNA10 IFNA14 IFNA16 IFNA17 IFNA21 IFNAR1 IFNAR2 IFNB1 JAK1 PTPN1 PTPN6 STAT1 STAT2 TYK2 SOCS1 SOCS3 +REACTOME_INTERFERON_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTERFERON_SIGNALING ADAR IRF9 IFITM3 IFITM2 NUP50 NUPL2 USP18 GBP4 GBP5 NUP35 LOC144383 GBP6 EGR1 EIF4A1 EIF4A2 EIF4E EIF4G1 EIF4G2 FCGR1A FCGR1B NUP205 FLNB NUP210 NUP188 DDX58 NUP62 IFI6 ARIH1 GBP1 GBP2 HLA-A HLA-B HLA-C HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DRB1 HLA-DRB3 HLA-DRB5 HLA-F HLA-G EIF4E3 ICAM1 IRF8 IFI27 IFI35 IFIT2 IFIT1 IFIT3 IFNA1 IFNA2 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNA10 IFNA14 IFNA16 IFNA17 IFNA21 IFNAR1 IFNAR2 IFNB1 IFNG IFNGR1 IFNGR2 NUP43 IRF1 IRF2 IRF3 IRF4 IRF5 IRF6 IRF7 ISG20 JAK1 JAK2 KPNA1 KPNB1 KPNA2 KPNA3 KPNA4 KPNA5 GBP7 CIITA LOC441019 MT2A MX1 MX2 NCAM1 NEDD4 NUP88 OAS1 OAS2 OAS3 HERC5 IP6K2 PIN1 PLCG1 NUP54 PML XAF1 PPM1B NUP133 PRKCD MAPK3 EIF2AK2 B2M PSMB8 NUP107 PTAFR PTPN1 PTPN2 PTPN6 RANBP2 RNASEL RPS27A LOC646981 HLA-K SP100 STAT1 STAT2 TPR RPS27AP11 TYK2 UBA52 UBA7 UBE2E1 UBE2N SUMO1 VCAM1 TRIM25 NUP37 NUP85 NUP214 AAAS CAMK2A CAMK2B CAMK2D SEH1L RAE1 IFITM1 PIAS1 OASL SOCS1 EIF4G3 SOCS3 UBE2L6 EIF4E2 CD44 NUP155 ISG15 NUP93 EIF4A3 NUPL1 POM121 NUP153 +REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING CYLD DDX58 TBK1 UBE2K IRF3 PCBP2 HERC5 PIN1 RNF125 OTUD5 MAVS RPS27A IFIH1 TNFAIP3 TRAF3 RPS27AP11 UBA52 UBA7 UBE2D1 UBE2D2 UBE2D3 TRIM25 NLRX1 NLRC5 RNF135 TAX1BP1 ATG12 UBE2L6 ATG5 ISG15 IKBKE +REACTOME_NFKB_AND_MAP_KINASES_ACTIVATION_MEDIATED_BY_TLR4_SIGNALING_REPERTOIRE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NFKB_AND_MAP_KINASES_ACTIVATION_MEDIATED_BY_TLR4_SIGNALING_REPERTOIRE NOD1 TAB1 CHUK CREB1 ATF2 MAPK14 TICAM1 AGER DUSP3 DUSP4 DUSP6 DUSP7 ELK1 TAB2 FOS LY96 TAB3 HMGB1 APP TICAM2 IKBKB IRAK1 IRAK2 JUN MEF2A MEF2C ATF1 NFKB2 NFKBIA NFKBIB PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D MAPK1 MAPK3 MAPK7 MAPK8 MAPK11 MAPK9 MAPK10 MAP2K1 MAP2K2 MAP2K3 MAP2K6 MAP2K7 RELA RPS6KA1 RPS6KA2 RPS6KA3 RPS27A S100A12 S100B SAA1 NOD2 MAP2K4 LOC650832 MAP3K7 TLR3 TLR4 TRAF6 RPS27AP11 UBA52 MAPKAPK3 IKBKG RIPK1 RIPK2 RPS6KA5 MAPKAPK2 CD14 CDK1 +REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING TCIRG1 ATP6V1G3 ATP6V0A2 ATP6V0D2 ATP6V1C2 ATP6V0A4 ATP6V1D ATP6V1H ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V0C ATP6V1C1 ATP6V1E1 ATP6V0B ATP6V1G2 STEAP3 MCOLN1 TF TFRC ATP6V0E1 ATP6V1E2 ATP6V0D1 ATP6V1F ATP6V1G1 +REACTOME_DSCAM_INTERACTIONS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DSCAM_INTERACTIONS MAPK14 DCC DSCAM PAK1 MAPK8 MAPK11 MAPK13 DSCAML1 RAC1 MAPK12 NTN1 +REACTOME_ION_CHANNEL_TRANSPORT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ION_CHANNEL_TRANSPORT ATP9A ATP8A1 ATP8B3 HTR3C ATP10B ATP11B ARHGEF9 ATP11A GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRG2 GABRG3 GABRR1 GABRR2 ATP2C1 GLRA1 GLRA2 GLRB ATP11C HTR3A ATP9B ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4 ATP1B1 ATP1B2 ATP1B3 FXYD2 ATP2A1 ATP2A2 ATP2A3 ATP2B2 ATP2B3 ATP4A ATP4B ATP8A2 ATP8B1 ATP7A ATP7B ATP10A ATP10D LOC644732 ATP8B4 GLRA3 HTR3B ATP2C2 +REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 PSMD14 PSMA8 EIF4G1 PSME4 PABPC1 HNRNPD HSPA1B HSPA8 HSPB1 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RPS27A LOC652607 LOC652826 RPS27AP11 UBA52 PSMF1 PSMD6 +REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX TAB1 TICAM1 TAB2 LY96 TAB3 TICAM2 RPS27A MAP3K7 TLR3 TLR4 TRAF6 RPS27AP11 UBA52 CD14 +REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS TANK CHUK CREBBP CYLD AGER EP300 DDX58 DAK TBK1 UBE2K HMGB1 IFNA1 IFNA2 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNA10 IFNA14 IFNA16 IFNA17 IFNA21 IFNB1 APP IKBKB IRF1 IRF2 IRF3 IRF7 MAP3K1 NFKB2 NFKBIA NFKBIB PCBP2 HERC5 PIN1 RNF125 OTUD5 MAVS RELA RPS27A S100A12 S100B SAA1 IFIH1 TNFAIP3 TRAF2 TRAF3 TRAF6 RPS27AP11 UBA52 UBA7 UBE2D1 UBE2D2 UBE2D3 TRIM25 DHX58 NLRX1 SIKE1 CASP8 NLRC5 RNF135 CASP10 IKBKG RIPK1 FADD TAX1BP1 ATG12 UBE2L6 ATG5 ISG15 IKBKE +REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 CHUK TICAM1 LY96 TICAM2 IKBKB TLR3 TLR4 IKBKG RIPK1 CD14 +REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT HTR3C ARHGEF9 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRG2 GABRG3 GABRR1 GABRR2 GLRA1 GLRA2 GLRB HTR3A GLRA3 HTR3B +REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER CDK7 DDB1 DDB2 ERCC1 ERCC2 ERCC3 ERCC4 ERCC5 GTF2H1 GTF2H2 GTF2H3 GTF2H4 MNAT1 RAD23B RPA1 RPA2 RPA3 LOC652672 LOC652857 GTF2H2B XPA XPC CCNH +REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION MED6 MED16 CDK4 CDK8 NCOA2 CEBPB CEBPD PPARGC1A MED8 CREBBP EBF1 EGR2 EP300 FABP4 MED19 NCOA6 CDK19 MED13L MED4 LEP MED11 LPL MED31 PCK1 ANGPTL4 MED15 PLIN1 PPARA PPARG MED1 MED18 MED9 MED29 RELA RXRA SLC2A4 SMARCD3 SREBF1 MED22 KLF5 TBL1X NR2F2 TGFB1 TNF WNT1 WNT10B TBL1XR1 MED25 NCOA3 MED10 PRIC285 NCOA1 HDAC3 CCNC CCND3 MED30 MED14 KLF4 ADIPOQ MED21 MED23 MED17 MED26 MED27 MED7 MED20 CD36 NCOR1 NCOR2 TGS1 MED24 MED12 +REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT STAM2 SNF8 CHMP4B VPS37A VPS37D CHMP2B VPS4A CHMP2A CHMP4A VPS36 VPS28 CHMP5 VTA1 CHMP3 VPS37C RPS27A TSG101 RPS27AP11 UBA52 CHMP6 VPS37B STAM VPS25 HGS CHMP7 CHMP4C VPS4B +REACTOME_MEIOTIC_RECOMBINATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MEIOTIC_RECOMBINATION RAD50 CDK2 CDK4 DMC1 HIST4H4 HIST2H3C HIST3H2BB SPO11 HIST1H2BA MLH3 HIST1H2AE HIST1H2AD H2AFX H2AFZ HIST1H2BD HIST1H2BB H3F3A H3F3B HIST2H3A H3F3AP5 MLH1 MRE11A MSH4 MSH5 NBN ATM HIST2H4B TEX15 PRDM9 RAD51 RAD51C RBBP8 RPA1 RPA2 RPA3 BLM H3F3AP6 LOC651610 HIST2H3D BRCA1 BRCA2 TOP3A HIST2H2AA4 LOC731820 HIST3H3 HIST1H4I HIST1H2AJ HIST1H2AC HIST1H2AB HIST2H2AA3 HIST2H2AC HIST1H2BG HIST1H2BL HIST1H2BN HIST1H2BM HIST1H2BF HIST1H2BE HIST1H2BH HIST1H2BI HIST1H2BC HIST1H2BO HIST2H2BE HIST1H3A HIST1H3D HIST1H3C HIST1H3E HIST1H3I HIST1H3G HIST1H3J HIST1H3H HIST1H3B HIST1H4A HIST1H4D HIST1H4F HIST1H4K HIST1H4J HIST1H4C HIST1H4H HIST1H4B HIST1H4E HIST1H4L HIST2H4A MND1 HIST1H2BK HIST1H3F HIST1H2BJ +REACTOME_IL_2_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IL_2_SIGNALING CSF2 CSF2RA CSF2RB PTK2B GRB2 HRAS IL2 IL2RA IL2RB IL2RG IL3 IL3RA IL5 IL5RA INPPL1 JAK1 JAK2 JAK3 KRAS LCK NRAS PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 MAPK1 MAPK3 MAP2K1 MAP2K2 PTPN6 RAF1 SHC1 SOS1 STAT5A STAT5B SYK YWHAB PIK3R3 CDK1 GAB2 +REACTOME_IL_6_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IL_6_SIGNALING IL6 IL6R IL6ST JAK1 JAK2 LOC649891 STAT1 STAT3 TYK2 CBL SOCS3 +REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION RASGRP1 RASGRP2 RAPGEF3 RAPGEF4 CRK CSK ADRA2A ADRA2B AKT1 F2 FGA FGB FGG FN1 GP1BA GP1BB GP5 GP9 GRB2 ITGA2B ITGB3 MPL PDPK1 APBB1IP PTK2 PTPN1 RAP1A RAP1B SHC1 SOS1 SRC SYK THPO TLN1 VWF BCAR1 +REACTOME_SIGNALING_BY_NOTCH http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_NOTCH HDAC6 HDAC5 MAMLD1 ADAM10 CDK8 ST3GAL6 TMED2 DTX2 CNTN1 CREBBP MIB2 JAG1 DTX1 E2F1 E2F3 EIF2C3 EIF2C4 EP300 SNW1 TNRC6B DTX4 NCSTN HEY1 HEY2 POFUT1 KAT2A HEYL EIF2C1 B4GALT1 EIF2C2 TNRC6A DLL1 HDAC1 HDAC2 HIF1A HES1 RBPJ JAG2 JUN HES5 LFNG ARRB1 ARRB2 MFNG MOV10 LOC441488 MYC NOTCH2 NOTCH3 NOTCH4 ATP2A1 ATP2A2 ATP2A3 FURIN APH1A HDAC7 DLL4 FBXW7 MAML3 PSENEN HDAC8 PSEN1 PSEN2 POGLUT1 MIB1 TNRC6C RAB6A CCND1 RFNG RPS27A SEL1L ST3GAL3 SKP1 ADAM17 TBL1X TFDP1 TLE1 TLE2 TLE3 TLE4 TP53 LOC728030 RPS27AP11 UBA52 TBL1XR1 HDAC11 APH1B HDAC10 MAML2 CUL1 NUMB DLK1 HDAC3 KAT2B CCNC NEURL DNER NCOR1 NCOR2 HDAC9 HDAC4 MAML1 RBX1 +REACTOME_LAGGING_STRAND_SYNTHESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_LAGGING_STRAND_SYNTHESIS POLD3 DNA2 FEN1 POLA2 LIG1 PCNA POLA1 POLD1 POLD2 PRIM1 PRIM2 POLD4 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 +REACTOME_INTRINSIC_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTRINSIC_PATHWAY A2M F2 F8 F9 F10 F11 F12 GP1BA GP1BB GP5 GP9 KLKB1 KNG1 PRCP C1QBP SERPING1 VWF +REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 E2F1 POLA2 PPP2R3B LOC441488 POLA1 PPP2CA PPP2CB PPP2R1A PPP2R1B PRIM1 PRIM2 RB1 TFDP1 +REACTOME_ETHANOL_OXIDATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ETHANOL_OXIDATION ADH1A ADH1B ADH1C ADH4 ADH6 ADH7 ALDH1A1 ALDH2 ACSS2 ACSS1 +REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS ACSL1 ACSL3 ACSL4 ACSL6 HSD17B12 ACSL5 ELOVL2 ELOVL5 ELOVL1 ELOVL4 ELOVL6 ELOVL7 ELOVL3 TECR +REACTOME_DNA_REPLICATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DNA_REPLICATION KIF20A CDK2 PSMD14 CDKN1A CDKN1B STAG1 NDC80 CENPA CENPC1 POLD3 NUDC STAG2 DBF4 KIF2C ZWINT PMF1 PSMA8 SPC24 SGOL2 SGOL1 DNA2 E2F1 E2F2 E2F3 SKA1 FEN1 MAPRE1 PSME4 CLASP1 ITGB3BP ORC6 ORC3 POLA2 CENPI AHCTF1 NSL1 FBXO5 RPA4 BIRC5 SKA2 NUP43 INCENP APITD1 KIF2A LIG1 CENPP MAD2L1 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 ORC1 ORC2 ORC4 ORC5 PAFAH1B1 GMNN PCNA GINS2 PLK1 POLA1 POLD1 POLD2 POLE POLE2 ERCC6L CCDC99 PPP1CC ZWILCH CDCA8 PPP2CA PPP2CB CENPQ PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E MCM10 PRIM1 PRIM2 NUP133 CENPN RCC2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 CASC5 PSMD3 PSMD4 PSMD5 NUP107 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 SPC25 TAOK1 POLD4 RAD21 RANBP2 RANGAP1 RB1 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 RPS27 RPS27A CLIP1 SEC13 CENPK LOC645084 GORASP1 CENPH LOC652826 BUB1 BUB1B RPS27AP11 SKA2L UBA52 XPO1 MIS12 CENPM NUP37 CENPO MLF1IP NUP85 DSN1 CENPT B9D2 NDEL1 CDT1 SEH1L KIF18A SMC1A CDC7 CDC45 NUF2 MAD1L1 GINS4 MCM8 KIF2B CCNA2 CCNA1 SMC3 CENPL ZW10 BUB3 AURKB PSMF1 KIF23 KNTC1 CKAP5 GINS1 PSMD6 CDC6 CDC20 +REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ THOC4 SRRM1 PAPOLA RNPS1 CLP1 NUDT21 U2AF2 LSM11 CSTF1 CSTF2 CSTF3 NCBP2 ZNF473 CPSF1 MAGOH NCBP1 NFX1 CDC40 PCF11 CPSF3 CPSF2 SRSF1 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 LOC643446 UPF3B SNRPB SNRPD3 SNRPE SNRPF SNRPG U2AF1 SLBP CPSF7 PABPN1 LSM10 SRSF9 SRSF11 DHX38 RBM8A +REACTOME_PKB_MEDIATED_EVENTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PKB_MEDIATED_EVENTS EIF4B EIF4E EIF4EBP1 EIF4G1 AKT2 MTOR EEF2K PDE3B PRKAG2 CAB39 PRKAG3 PPM1A STRADB PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 RPTOR RHEB RPS6 RPS6KB1 MLST8 LOC644462 STK11 TSC1 TSC2 CAB39L STRADA +REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION DHFR E2F1 ORC6 ORC3 POLA2 FBXO5 PPP2R3B LOC441488 ORC1 ORC2 ORC4 ORC5 PCNA POLA1 PPP2CA PPP2CB PPP2R1A PPP2R1B PRIM1 PRIM2 RB1 RRM2 DHFRP1 TFDP1 TK2 TYMS CDT1 CDC45 MCM8 CCNA1 CCNB1 CCNE1 CDK1 CDC6 CDC25A +REACTOME_METABOLISM_OF_CARBOHYDRATES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_CARBOHYDRATES ABCC5 GPC6 UST SLC25A13 B3GNT3 ST3GAL6 B3GNT2 NUP50 HPSE LYVE1 B3GNT1 KERA NUPL2 TREH B4GALT7 CHST14 B3GALT6 NUP35 B3GAT2 VCAN NCAN CSPG4 SLC25A10 DCN CHST13 ACAN AGL ENO1 ENO2 ENO3 EXT1 EXT2 FBP1 PRPS1L1 GPC2 HS3ST5 GPC4 ALDOA GPC5 CHSY1 ALDOB RPIA ALDOC NUP205 NUP210 FMOD NUP188 CHST5 NUP62 G6PC G6PD SLC37A4 PGLS GALE GALK1 GALT GAPDH GLCE B3GAT3 GBE1 GAPDHS GCK GCKR HS6ST3 B4GALT1 B3GAT1 GPC3 GLB1 AMY1A AMY1B AMY1C AMY2A GNS AMY2B GOT1 GOT2 GPC1 GPI GXYLT1 GUSB GYG1 DSE GYS1 GYS2 HAS1 HAS2 HAS3 HEXA HEXB HK1 HK2 HK3 HMMR HSPG2 NDST1 HYAL1 CHSY3 IDS IDUA NUP43 AGRN KHK LCT LUM ARSB CHST6 MDH1 MDH2 NAGLU NUP88 OMD OGN CHST11 PC PCK1 PCK2 CHST15 PFKFB1 PFKFB2 PFKFB3 PFKFB4 PFKL PFKM PFKP PGAM1 PGAM2 PGD PGK1 PGM1 PHKA1 PHKA2 PHKB PHKG1 PHKG2 PKLR PKM2 NUP54 CHPF2 PPP2CA PPP2CB PPP2R1A PPP2R1B PGM2 PPP2R5D CSGALNACT2 PRELP CHST12 STAB2 PRKACA PRKACB PRKACG NUP133 CSGALNACT1 PRPS1 PRPS2 CHST7 NUP107 G6PC2 PYGB PYGL PYGM RANBP2 HPSE2 RPE BGN SDC1 BCAN SDC2 SDC4 LOC642969 LOC644504 LOC644691 SGSH NDST4 PHKA1P1 HS3ST6 SI ST3GAL1 ST3GAL2 ST3GAL3 LOC648749 LOC729020 LOC650556 SLC2A1 SLC2A2 SLC2A3 SLC2A4 SLC2A5 SLC5A1 LOC652899 SLC9A1 SLC25A1 TALDO1 TKT TPI1 TPR GXYLT2 HS6ST1P1 TPI1P1 LOC730418 LOC730924 UGP2 NUP37 B3GNT4 CHPF NUP85 CALM1 NUP214 CALM2 CALM3 AAAS SEH1L CHST9 SLC25A11 RAE1 NDST2 CHST1 SLC25A12 HYAL2 B4GALT4 B4GALT3 B4GALT2 FBP2 GYG2 MGAM HS6ST2 G6PC3 B3GNT7 B4GALT6 B4GALT5 NDST3 HS6ST1 CHST2 CHST3 CD44 NUP155 HS2ST1 SDC3 NUP93 NUPL1 POM121 HS3ST4 HS3ST3B1 HS3ST3A1 HS3ST2 HS3ST1 NUP153 +REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS MGLL FABP4 LIPE ABHD5 PLIN1 PPP1CA PPP1CB PPP1CC PRKACA PRKACB PRKACG LOC730418 CAV1 +REACTOME_SIGNALING_BY_INSULIN_RECEPTOR http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_INSULIN_RECEPTOR TCIRG1 FRS2 THEM4 ATP6V1G3 CRK KLB DOK1 EIF4B EIF4E EIF4EBP1 EIF4G1 AKT2 FGF1 FGF2 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGF10 FGFR1 FGFR3 FGFR2 FGFR4 ATP6V0A2 ATP6V0D2 ATP6V1C2 MTOR GAB1 SHC2 FGF20 FGF22 GRB2 GRB10 EEF2K PIK3R4 HRAS INS INSR IRS1 KRAS NRAS ATP6V0A4 ATP6V1D PDE3B PRKAG2 ATP6V1H PDPK1 CAB39 ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V0C ATP6V1C1 PIK3C3 ATP6V1E1 PIK3CA PIK3CB PIK3R1 PIK3R2 ATP6V0B SHC3 ATP6V1G2 PRKAG3 TLR9 PPM1A STRADB PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 MAPK1 MAPK3 MAP2K1 MAP2K2 RPTOR TRIB3 RAF1 RHEB RPS6 RPS6KB1 MLST8 LOC644462 SHC1 SOS1 STK11 TSC1 TSC2 LOC729120 LOC730244 YWHAB FGF23 CAB39L IRS2 FGF18 FGF17 ATP6V0E1 ATP6V1E2 ATP6V0D1 STRADA ATP6V1F KL ATP6V1G1 CDK1 FGF19 +REACTOME_SIGNAL_ATTENUATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNAL_ATTENUATION CRK DOK1 SHC2 GRB2 GRB10 INS INSR IRS1 SHC3 MAPK3 SHC1 SOS1 LOC730244 IRS2 +REACTOME_PURINE_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PURINE_METABOLISM ADA PAICS ADSSL1 ADK ADSL ADSS ADAL DCK DGUOK NT5C2 GART AMPD1 AMPD2 AMPD3 GMPR GPX1 NT5C HPRT1 APRT IMPDH1 IMPDH2 ATIC PNP NT5E GMPR2 PFAS PPAT XDH NT5C1A CAT GMPS NT5C1B GDA +REACTOME_SOS_MEDIATED_SIGNALLING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SOS_MEDIATED_SIGNALLING GRB2 HRAS IRS1 KRAS NRAS MAPK1 MAPK3 MAP2K1 MAP2K2 RAF1 SOS1 YWHAB IRS2 CDK1 +REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER SNAPC5 POLR3F POLR3C POLR3A LZTS1 POLR3H POLR1D POLR3K POLR2E POLR2F POLR2H POLR2K POLR2L POU2F1 BRF2 POLR3B POLR3E POLR3D SNAPC1 SNAPC2 SNAPC3 SNAPC4 TBP ZNF143 POLR3GL POLR1C +REACTOME_APOPTOSIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APOPTOSIS BCL2L11 DNM1L BCAP31 PSMD14 ADD1 DYNLL2 PSMA8 CTNNB1 DAPK1 DAPK3 DCC DFFA DFFB DSG1 DSG2 DSG3 DSP E2F1 AKT1 UNC5B ACIN1 PSME4 FNTA DAPK2 APPL1 GAS2 BBC3 DBNL GSN GZMB H1F0 HIST1H1C HIST1H1D HIST1H1E HIST1H1B HIST1H1A HMGB1 HMGB2 APAF1 APC BIRC2 XIAP FAS FASLG KPNA1 KPNB1 LMNA LMNB1 MAPT LOC441488 NMT1 OCLN PAK2 MST4 PKP1 PLEC PMAIP1 CYCS PPP3R1 PRKCD PRKCQ MAPK8 DIABLO PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 BAD PSME1 PSME2 PTK2 BAK1 BAX BCL2 BCL2L1 ROCK1 RPS27A SATB1 BID LOC647859 LOC652460 LOC652826 BMX SPTAN1 TFDP1 TJP1 TNF TNFRSF1A TP53 TRAF2 ROCK1P1 RPS27AP11 UBA52 VIM YWHAB ARHGAP10 CASP3 CASP6 CASP7 CASP8 CASP9 STK24 CASP10 DYNLL1 TRADD RIPK1 TNFSF10 FADD TNFRSF10B CFLAR UNC5A BMF TJP2 PSMF1 MAGED1 PSMD6 CDH1 +REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT CETP MGLL APOA5 CLPS ABCA1 A2M ALB FABP4 LDLRAP1 HSPG2 APOA1 APOA2 APOB APOC2 APOC3 APOE LCAT LDLR LIPC LIPE LPA LPL MTTP P4HB ABHD5 SAR1B PLIN1 PLTP PNLIP PNLIPRP2 PPP1CA PPP1CB PPP1CC PRKACA PRKACB PRKACG SDC1 ABCG5 ABCG8 BMP1 LOC730418 CUBN AMN CAV1 SCARB1 ABCG1 +REACTOME_HEMOSTASIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HEMOSTASIS AKT3 SH2B3 KIF20A RASGRP1 CDK2 CDK5 RASGRP2 KCNMB2 ABCC4 MRVI1 HMG20B RAPGEF3 VAV3 MERTK CAP1 SH2B2 GNA13 GNB5 CFL1 PDE10A EHD1 KIF2C RAPGEF4 SLC7A9 AKAP10 VPS45 MGLL CLU AMICA1 HIST2H3C COL1A1 COL1A2 LOC128192 LOC131691 CREBBP DGKK CRK GATA5 SIRPA MAPK14 CSK PIK3R6 KLC3 ADRA2A ADRA2B CXADR DGKA DGKB DGKG DGKH DGKQ ZFPM1 CFD DOCK1 DOCK2 DOCK3 EGF A2M EP300 AKT1 AKT2 ALB F2 F2R F2RL2 F3 F5 F7 F8 F9 F10 F11 F12 F13A1 F13B FCER1G JMJD1C DAGLB FGA FGB ALDOA FGG FGR FIGF MMRN1 KIFAP3 HABP4 KDM1A RCOR1 DOCK9 FN1 ZFPM2 SLC7A8 CBX5 PIK3R5 SLC16A8 SLC7A11 PPIL2 MAFF KIF4A ABL1 FYN SIN3A SH2B1 KIF26A GATA1 GATA2 GATA3 GATA4 GATA6 LAT KCNMB3 BRPF3 KCNMB4 GNA11 GNA12 GNA15 GNAI1 GNAI2 GNAI3 GNAQ GNAS GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GP1BA GP1BB GP5 GP9 ANGPT1 ANGPT2 KIF4B GRB2 GRB7 GRB14 SCG3 RACGAP1 GUCY1A2 GUCY1A3 GUCY1B3 H3F3A H3F3B HBB HBD HBE1 HBG2 HDAC1 HDAC2 HGF EHD2 HRAS HRG HSPA5 HIST2H3A APOA1 APOB PPIAP8 IFNA1 IFNA2 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNA10 IFNA14 IFNA16 IFNA17 IFNA21 IFNB1 H3F3AP5 APP IRF1 IRF2 IRF3 IRF7 ITGA2 ITGA2B ITGA3 ITGA5 ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITPK1 ITPR2 ITPR3 JAK2 KCNMB1 KIF2A KIF3C KIF5A KIF5B KLKB1 KNG1 KLC1 KIF11 KIFC1 KIF22 KRAS RHOA RHOB L1CAM RHOG LAMP2 LCK LCP2 LYN ARRB1 ARRB2 MAFG MAG MMP1 MPL LOC441511 MYB SERPINC1 NFE2 ATP1B1 ATP1B2 ATP1B3 NOS1 NOS2 NOS3 ATP2A1 ATP2A2 ATP2A3 NRAS ATP2B2 ATP2B3 OLR1 P2RX1 P2RY1 SERPINE1 SERPINB2 AK3 F11R PDE11A PDE1A ANGPT4 PDE2A PDE3A PDE3B PDE6A PDE6G PDE9A PDE1B PDGFA PDGFB PDE6B PDPK1 PECAM1 GNG13 PF4 PF4V1 PFN1 SERPINA1 PIK3CA PIK3CB PIK3CG PIK3R1 PIK3R2 PLA2G4A PLAT PLAU PLAUR PLCG1 PLCG2 PLG PLEK SERPINF2 TREM1 GNG2 APBB1IP PPBP PPIA PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E SIRPG PRCP SRGN DOCK10 PRKACA MFN1 PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCQ PRKCZ PRKG1 PRKG2 MAPK1 MAPK3 GNG12 PROC PROS1 SLC7A10 PSAP KIF15 TRPC7 PTGIR PTK2 DOCK6 PTPN1 PTPN6 JAM2 RAB5A RAC1 RAC2 RAD51C RAD51B RAF1 RAP1A RAP1B GNB4 SELL SELP ZFYVE20 POTEM KIF9 LOC643997 H3F3AP6 SHC1 P2RY12 KLC2 SLC3A2 LOC652612 PPIAP22 HIST2H3D LOC654188 SLC8A2 SLC8A1 SLC8A3 SLC16A1 SOD1 SOS1 SPARC SPN SRC STIM1 STX4 STXBP3 BSG SYK TBXA2R TEK TF TFPI TGFB1 TGFB2 TGFB3 LEFTY2 THBD THBS1 THPO TIMP1 C1QBP TLN1 SERPING1 TMSB4X TP53 TRPC3 TRPC6 TUBA4A LOC727848 LOC730221 LOC730335 LOC730418 LOC731820 VAV1 VCL VEGFA VEGFB VEGFC VWF WEE1 DAGLA YES1 YWHAZ LRP8 MAFK DOCK5 CALM1 CALM2 CALM3 ACTN4 CALU SLC7A5 AKAP1 DOCK8 CABLES2 KIF18A CAPZA1 CAPZA2 HIST1H3A HIST1H3D HIST1H3C HIST1H3E HIST1H3I HIST1H3G HIST1H3J HIST1H3H HIST1H3B JAM3 KIF2B ORAI1 PIK3R3 DGKE DGKD CAV1 PDE5A ACTN1 ACTN2 HIST1H3F KLC4 F2RL3 DOK2 SLC7A7 SLC7A6 ESAM SLC16A3 CD2 DGKI CABLES1 CD9 KIF3B GNG8 CD36 KIF23 BCAR1 CD47 CD48 GNA14 CD58 CD63 DOCK4 MFN2 WDR1 CDC42 +REACTOME_INFLUENZA_LIFE_CYCLE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INFLUENZA_LIFE_CYCLE NUP50 NUPL2 RPL35 CLTA CLTC NUP35 RPL7AP27 FAU NUP205 NUP210 NUP188 RPL13A NUP62 RPL36 RPL10P16 FAM153A GRSF1 GTF2F1 GTF2F2 HSPA1B HSP90AA1 RPL36P14 NUP43 KPNA1 KPNB1 IPO5 RPSAP12 RPS8P10 RPL7AP66 RPL10P9 RPS12P4 RPSA RPS26P10 RPL23AP2 RPS12P22 RPL21P29 RPS26P35 RPL10A NUP88 RPL26L1 NUP54 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L NUP133 DNAJC3 NUP107 RAN RANBP2 RPL3 RPL3L RPL4 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL10 RPL11 RPL12 RPL13 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL23A RPL24 RPL26 RPL27 RPL30 RPL27A RPL28 RPL29 RPL31 RPL32 RPL34 RPL35A RPL37 RPL37A RPL38 RPL39 RPL41 RPL36A RPLP0 RPLP1 RPLP2 RPS2 RPS3 RPS3A RPS4X RPS4Y1 RPS5 RPS6 RPS7 RPS8 RPS9 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS18 RPS19 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS28 RPS29 RPL6P19 LOC641895 RPL36AP31 RPS29P3 RPS26P28 RPL36AP8 RPL26P22 RPS26P20 RPS15AP11 RPS26P50 RPL22P11 RPL17P6 RPS13P8 RPS28P4 RPL32P16 LOC646184 RPS28P7 RPL12P2 LOC647074 RPL23AP42 RPL5P1 RPL36AP51 LOC649602 RPS28P9 RPL34P27 LOC651825 LOC651894 RPL26P30 RPSAP9 RPL19P9 RPL21P119 RPL31P17 LOC653881 TPR RPL31P31 RPL15P17 RPL23AP18 RPL26P24 RPL21P75 RPS27AP11 RPS26P7 RPL21P134 RPS26P25 RPS19P3 RPL36AP23 RPS18P10 RPL17P36 RPL36AP37 RPL21P16 RPL23AP74 RPS15P5 RPL23AP63 RPS10P9 LOC730343 RPS18P5 UBA52 RPL34P31 XPO1 NUP37 NUP85 NUP214 AAAS CALR SEH1L CANX RAE1 RPL14 RPL23 NUP155 NUP93 NUPL1 POM121 NUP153 +REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION RPL35 RPL7AP27 FAU RPL13A RPL36 RPL10P16 FAM153A GRSF1 GTF2F1 GTF2F2 HSP90AA1 RPL36P14 IPO5 RPSAP12 RPS8P10 RPL7AP66 RPL10P9 RPS12P4 RPSA RPS26P10 RPL23AP2 RPS12P22 RPL21P29 RPS26P35 RPL10A RPL26L1 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L DNAJC3 RPL3 RPL3L RPL4 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL10 RPL11 RPL12 RPL13 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL23A RPL24 RPL26 RPL27 RPL30 RPL27A RPL28 RPL29 RPL31 RPL32 RPL34 RPL35A RPL37 RPL37A RPL38 RPL39 RPL41 RPL36A RPLP0 RPLP1 RPLP2 RPS2 RPS3 RPS3A RPS4X RPS4Y1 RPS5 RPS6 RPS7 RPS8 RPS9 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS18 RPS19 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS28 RPS29 RPL6P19 LOC641895 RPL36AP31 RPS29P3 RPS26P28 RPL36AP8 RPL26P22 RPS26P20 RPS15AP11 RPS26P50 RPL22P11 RPL17P6 RPS13P8 RPS28P4 RPL32P16 LOC646184 RPS28P7 RPL12P2 LOC647074 RPL23AP42 RPL5P1 RPL36AP51 LOC649602 RPS28P9 RPL34P27 LOC651825 LOC651894 RPL26P30 RPSAP9 RPL19P9 RPL21P119 RPL31P17 LOC653881 RPL31P31 RPL15P17 RPL23AP18 RPL26P24 RPL21P75 RPS27AP11 RPS26P7 RPL21P134 RPS26P25 RPS19P3 RPL36AP23 RPS18P10 RPL17P36 RPL36AP37 RPL21P16 RPL23AP74 RPS15P5 RPL23AP63 RPS10P9 LOC730343 RPS18P5 UBA52 RPL34P31 RPL14 RPL23 +REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY NUP50 NUPL2 NUP35 NUP205 NUP210 NUP188 NUP62 NUP43 NUP88 NUP54 NUP133 NUP107 RAN RANBP2 TPR XPO1 NUP37 NUP85 NUP214 AAAS SEH1L RAE1 NUP155 NUP93 NUPL1 POM121 NUP153 +REACTOME_HIV_INFECTION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HIV_INFECTION AP1M2 PSMD14 CDK7 CDK9 NUP50 RCC1 NUPL2 PSIP1 SUPT16H AP2M1 AP1S1 AP2S1 CCR5 LOC128192 NUP35 LOC131691 VPS37A PSMA8 VPS37D AP2A1 AP2A2 AP1B1 AP2B1 AP1G1 DOCK2 ERCC2 ERCC3 FEN1 NCBP2 NUP205 PSME4 NUP210 NUP188 NUP62 FYN XRCC6 COBRA1 SLC25A4 SLC25A5 SLC25A6 GTF2A1 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 HCK HLA-A HMGA1 PPIAP8 NUP43 ARF1 KPNA1 KPNB1 LOC389901 LCK LIG1 LIG4 MNAT1 LOC440577 NCBP1 NMT1 NPM1 NUP88 PAK2 VPS28 TH1L ATP6V1H NUP54 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L PPIA VPS37C PACS1 NUP133 B2M PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 NUP107 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RAC1 RAN RANBP1 RANBP2 RANGAP1 APOBEC3G RPS27A LOC643997 TCEB1P3 LOC645870 HLA-K SKP1 LOC652826 LOC652857 PPIAP22 GTF2H2B LOC654188 SSRP1 SUPT4H1 SUPT5H TAF1 TAF4 TAF4B TAF5 TAF6 TAF9 TAF10 TAF11 TAF12 TAF13 TBP TCEA1 TCEB1 TCEB2 TCEB3 TPR TSG101 RPS27AP11 UBA52 WHSC2 XPO1 XRCC4 XRCC5 CXCR4 NUP37 RDBP VPS37B NUP85 NUP214 CUL5 AAAS ELL SEH1L RAE1 RNMT RNGTT BANF1 AP1S2 AP1M1 BTRC CCNH CCNT1 CCNT2 CTDP1 CD247 CD4 CD8B NMT2 CD28 PSMF1 NUP155 NUP93 NUPL1 ELMO1 PSMD6 POM121 NUP153 RBX1 +REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS NUP50 NUPL2 NUP35 NUP205 NUP210 NUP188 NUP62 NUP43 KPNA1 KPNB1 NUP88 NUP54 NUP133 NUP107 RANBP2 TPR NUP37 NUP85 NUP214 AAAS SEH1L RAE1 NUP155 NUP93 NUPL1 POM121 NUP153 +REACTOME_HIV_LIFE_CYCLE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HIV_LIFE_CYCLE CDK7 CDK9 NUP50 RCC1 NUPL2 PSIP1 SUPT16H CCR5 LOC128192 NUP35 LOC131691 VPS37A VPS37D ERCC2 ERCC3 FEN1 NCBP2 NUP205 NUP210 NUP188 NUP62 XRCC6 COBRA1 GTF2A1 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 HMGA1 PPIAP8 NUP43 LOC389901 LIG1 LIG4 MNAT1 NCBP1 NMT1 NUP88 VPS28 TH1L NUP54 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L PPIA VPS37C NUP133 NUP107 RAN RANBP1 RANBP2 RANGAP1 RPS27A LOC643997 TCEB1P3 LOC645870 LOC652857 PPIAP22 GTF2H2B LOC654188 SSRP1 SUPT4H1 SUPT5H TAF1 TAF4 TAF4B TAF5 TAF6 TAF9 TAF10 TAF11 TAF12 TAF13 TBP TCEA1 TCEB1 TCEB2 TCEB3 TPR TSG101 RPS27AP11 UBA52 WHSC2 XPO1 XRCC4 XRCC5 CXCR4 NUP37 RDBP VPS37B NUP85 NUP214 AAAS ELL SEH1L RAE1 RNMT RNGTT BANF1 CCNH CCNT1 CCNT2 CTDP1 CD4 NMT2 NUP155 NUP93 NUPL1 POM121 NUP153 +REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT NCBP2 COBRA1 GTF2F1 GTF2F2 NCBP1 TH1L POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L SUPT4H1 SUPT5H WHSC2 RDBP CTDP1 +REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE PSIP1 CCR5 LOC128192 LOC131691 FEN1 XRCC6 HMGA1 PPIAP8 LOC389901 LIG1 LIG4 PPIA LOC643997 LOC645870 PPIAP22 LOC654188 XRCC4 XRCC5 CXCR4 BANF1 CD4 +REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS AP1M2 PSMD14 CDK9 NUP50 RCC1 NUPL2 PSIP1 AP2M1 AP1S1 AP2S1 LOC128192 NUP35 LOC131691 PSMA8 AP2A1 AP2A2 AP1B1 AP2B1 AP1G1 DOCK2 NUP205 PSME4 NUP210 NUP188 NUP62 FYN SLC25A4 SLC25A5 SLC25A6 HCK HLA-A HMGA1 PPIAP8 NUP43 ARF1 KPNA1 KPNB1 LCK LOC440577 NPM1 NUP88 PAK2 ATP6V1H NUP54 PPIA PACS1 NUP133 B2M PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 NUP107 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RAC1 RAN RANBP1 RANBP2 RANGAP1 APOBEC3G RPS27A LOC643997 TCEB1P3 LOC645870 HLA-K SKP1 LOC652826 PPIAP22 LOC654188 TCEB1 TCEB2 TPR RPS27AP11 UBA52 XPO1 NUP37 NUP85 NUP214 CUL5 AAAS SEH1L RAE1 BANF1 AP1S2 AP1M1 BTRC CCNT1 CD247 CD4 CD8B CD28 PSMF1 NUP155 NUP93 NUPL1 ELMO1 PSMD6 POM121 NUP153 RBX1 +REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION POLR3F POLR3C POLR3A LZTS1 POLR3H NFIB POLR1D POLR3K POLR2E POLR2F POLR2H POLR2K POLR2L POLR3B POLR3E POLR3D SSB POLR3GL POLR1C +REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ ATP5H ATP5L UQCR11 NDUFA11 COX4I1 COX5B COX6A1 COX6B1 COX6C COX7B COX7C COX8A CYC1 ETFA ETFB ETFDH UQCRQ NDUFS7 UQCRHL ATP6 ATP8 COX1 COX2 COX3 CYTB ND1 ND2 ND3 ND4 ND4L ND5 ND6 NDUFA1 NDUFA2 NDUFA3 NDUFA4 NDUFA5 NDUFA6 NDUFA7 NDUFA8 NDUFA9 NDUFA10 NDUFAB1 NDUFB1 NDUFB2 NDUFB3 NDUFB4 NDUFB5 NDUFB6 NDUFB7 NDUFB8 NDUFB9 NDUFB10 NDUFC1 NDUFC2 NDUFS1 NDUFS2 NDUFS3 NDUFV1 NDUFS4 NDUFS5 NDUFS6 NDUFS8 NDUFV2 NDUFV3 ATP5A1 ATP5B ATP5C1 NDUFA13 ATP5D ATP5E ATP5F1 ATP5G1 ATP5I ATP5J ATP5O CYCS NDUFA12 SDHA SDHB SDHC SDHD LOC642727 MTND5P10 UQCRBP1 LOC651820 LOC727947 UCP1 UCP2 UCP3 UQCRB UQCRC1 UQCRC2 UQCRFS1 UQCRH COX7A2L COX5A ATP5J2 +REACTOME_FORMATION_OF_THE_HIV1_EARLY_ELONGATION_COMPLEX http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FORMATION_OF_THE_HIV1_EARLY_ELONGATION_COMPLEX CDK7 ERCC2 ERCC3 NCBP2 COBRA1 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 MNAT1 NCBP1 TH1L POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L LOC652857 GTF2H2B SUPT4H1 SUPT5H WHSC2 RDBP CCNH CTDP1 +REACTOME_RAF_MAP_KINASE_CASCADE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RAF_MAP_KINASE_CASCADE HRAS KRAS NRAS MAPK1 MAPK3 MAP2K1 MAP2K2 RAF1 YWHAB CDK1 +REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS GTF2F1 GTF2F2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L +REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE CDK7 CDK9 NUP50 RCC1 NUPL2 SUPT16H NUP35 VPS37A VPS37D ERCC2 ERCC3 NCBP2 NUP205 NUP210 NUP188 NUP62 COBRA1 GTF2A1 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 NUP43 MNAT1 NCBP1 NMT1 NUP88 VPS28 TH1L NUP54 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L VPS37C NUP133 NUP107 RAN RANBP1 RANBP2 RANGAP1 RPS27A TCEB1P3 LOC652857 GTF2H2B SSRP1 SUPT4H1 SUPT5H TAF1 TAF4 TAF4B TAF5 TAF6 TAF9 TAF10 TAF11 TAF12 TAF13 TBP TCEA1 TCEB1 TCEB2 TCEB3 TPR TSG101 RPS27AP11 UBA52 WHSC2 XPO1 NUP37 RDBP VPS37B NUP85 NUP214 AAAS ELL SEH1L RAE1 RNMT RNGTT CCNH CCNT1 CCNT2 CTDP1 NMT2 NUP155 NUP93 NUPL1 POM121 NUP153 +REACTOME_SHC_MEDIATED_SIGNALLING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SHC_MEDIATED_SIGNALLING SHC2 GRB2 HRAS KRAS NRAS SHC3 MAPK1 MAPK3 MAP2K1 MAP2K2 RAF1 SHC1 SOS1 YWHAB CDK1 +REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS NUP50 NUPL2 PSIP1 NUP35 NUP205 NUP210 NUP188 NUP62 SLC25A4 SLC25A5 SLC25A6 HMGA1 NUP43 KPNA1 NUP88 NUP54 NUP133 NUP107 RANBP2 LOC645870 TPR NUP37 NUP85 NUP214 AAAS SEH1L RAE1 BANF1 NUP155 NUP93 NUPL1 POM121 NUP153 +REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING ATP5H ATP5L ATP6 ATP8 ATP5A1 ATP5B ATP5C1 ATP5D ATP5E ATP5F1 ATP5G1 ATP5I ATP5J ATP5O LOC642727 ATP5J2 +REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 PSMD14 ANAPC10 UBE2C PSMA8 PSME4 CDC26 ANAPC2 ANAPC4 ANAPC5 ANAPC7 ANAPC11 PLK1 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RPS27A ANAPC1 LOC647654 LOC649620 SKP2 LOC650621 LOC651763 LOC652826 AURKA RPS27AP11 CDC26P1 LOC730594 UBA52 UBE2D1 UBE2E1 CDC23 CDC16 AURKB PTTG1 PSMF1 PSMD6 CDC20 CDC27 +REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS CDK2 DBF4 CHEK1 ORC6 ORC3 HUS1 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 ORC1 ORC2 ORC4 ORC5 ATR MCM10 RAD1 RAD9A RAD17 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 LOC645084 LOC648152 LOC651921 CDC7 CDC45 ATRIP MCM8 CDC6 CDC25A CDC25C +REACTOME_UNWINDING_OF_DNA http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_UNWINDING_OF_DNA MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 GINS2 CDC45 GINS4 MCM8 GINS1 +REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS PSMD14 ANAPC10 UBE2C PSMA8 PSME4 CDC26 ANAPC2 ANAPC4 MAD2L1 ANAPC5 ANAPC7 ANAPC11 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RPS27A ANAPC1 LOC647654 LOC649620 LOC650621 LOC651763 LOC652826 BUB1B RPS27AP11 CDC26P1 LOC730594 UBA52 UBE2D1 UBE2E1 CDC23 CDC16 CCNB1 BUB3 PTTG1 PSMF1 CDK1 PSMD6 CDC20 CDC27 +REACTOME_GLUCURONIDATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLUCURONIDATION UGT2B11 UGT2A1 SLC35D1 UGT2B28 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9 UGT1A4 UGT1A1 UGT1A3 UGDH UGP2 UGT2B4 UGT2B7 UGT2B10 UGT2B17 +REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C PSMD14 ANAPC10 UBE2C CDC26 ANAPC2 ANAPC4 ANAPC5 ANAPC7 ANAPC11 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RPS27A ANAPC1 LOC647654 LOC649620 LOC650621 LOC651763 LOC652826 RPS27AP11 CDC26P1 LOC730594 UBA52 UBE2D1 UBE2E1 CDC23 CDC16 PSMF1 PSMD6 CDC27 +REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE TLR6 NOD1 TAB1 IRAK3 TIRAP CHUK CREB1 ATF2 MAPK14 AGER DUSP3 DUSP4 DUSP6 DUSP7 ELK1 TAB2 FOS LY96 PELI3 TAB3 HMGB1 APP IKBKB IRAK1 IRAK2 JUN TMEM189-UBE2V1 MEF2A MEF2C MAP3K1 MYD88 ATF1 NFKB2 NFKBIA NFKBIB IRAK4 ECSIT PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D MAPK1 MAPK3 MAPK7 MAPK8 MAPK11 MAPK9 MAPK10 MAP2K1 MAP2K2 MAP2K3 MAP2K6 MAP2K7 PELI2 PELI1 SIGIRR RELA RPS6KA1 RPS6KA2 RPS6KA3 RPS27A S100A12 S100B SAA1 NOD2 MAP2K4 LOC650832 MAP3K7 BTK TLR1 TLR2 TLR4 TRAF6 RPS27AP11 UBA52 UBE2N MAPKAPK3 IKBKG RIPK2 RPS6KA5 MAPKAPK2 CDK1 +REACTOME_INNATE_IMMUNE_SYSTEM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INNATE_IMMUNE_SYSTEM TANK TLR6 NOD1 TAB1 TXNIP CNPY3 MASP2 CFHR3 RIPK3 IRAK3 NLRP3 TIRAP CHUK DEFB118 CCR2 CCR6 CR1 CREB1 ATF2 CREBBP CRP DEFB104A DEFB127 DEFB129 MAPK14 TICAM1 CTSB CTSK CTSL1 CTSS CYLD CD55 DDOST DEFA1 DEFA3 DEFA4 DEFA5 DEFA6 DEFB1 DEFB4A CFD DNM1 AGER DNM2 DUSP3 DUSP4 DUSP6 DUSP7 ELK1 EP300 NLRP1 TAB2 FOS DDX58 LY96 PANX1 DEFB105A DEFB106A DEFB107A DEFB108B DEFB110 DEFB112 DEFB113 DEFB114 DEFB115 DEFB116 DEFB119 DEFB121 DEFB123 DEFB124 DEFB125 DEFB128 DEFB130 PELI3 UNC93B6 TAB3 DAK PYCARD TBK1 CFH PIK3R4 UBE2K HMGB1 BIRC2 BIRC3 HSP90AB1 CFI IFNA1 IFNA2 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNA10 IFNA14 IFNA16 IFNA17 IFNA21 IFNB1 APP TICAM2 IKBKB IRAK1 IRAK2 IRF1 IRF2 IRF3 IRF7 JUN TMEM189-UBE2V1 LBP LGALS3 DEFB132 UNC93B2 CD180 DEFB103A MBL2 ART1 CD46 MEF2A MEF2C MEFV MAP3K1 MYD88 ATF1 NFKB2 NFKBIA NFKBIB P2RX7 DEFB107B DEFB104B DEFB106B DEFB105B PCBP2 IRAK4 HERC5 TLR7 ECSIT TLR8 PIK3C3 PIN1 PLCG2 TLR9 RNF125 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D OTUD5 PRKCSH DEFB103B MAPK1 MAPK3 MAPK7 MAPK8 MAPK11 MAPK9 MAPK10 MAPK13 MAP2K1 MAP2K2 MAP2K3 MAP2K6 MAP2K7 PROS1 LGMN PRSS2 MASP1 PELI2 PELI1 MAVS NLRC4 SIGIRR BCL2 RELA BCL2L1 DEFB135 DEFB136 DEFB134 RPS6KA1 RPS6KA2 RPS6KA3 RPS27A S100A12 S100B SAA1 CFB MAPK12 NOD2 IFIH1 ZFYVE20 MAP2K4 CARD9 DEFB131 LOC644816 LOC650832 LOC651536 LOC653879 MAP3K7 BTK TLR1 TLR2 TLR3 TLR4 TLR5 C1QA TNFAIP3 C1QB C1QC C1S C2 C3 HSP90B1 TRAF2 TRAF3 TRAF6 C4A C4BPA C4BPB C5 DEFA1B DEFB4B RPS27AP11 C6 TXN LOC729523 C7 C8A LOC731066 UBA52 UBA7 LOC731949 C8B UBE2D1 UBE2D2 UBE2D3 C8G UBE2N C9 TRIM25 MAPKAPK3 DHX58 NLRX1 SIKE1 ZBP1 UNC93B1 DEFB126 TLR10 CAPZA1 CAPZA2 CASP1 CASP2 CASP4 CASP8 EEA1 NLRC5 CASP9 RNF135 CASP10 IKBKG RIPK1 RIPK2 FADD TAX1BP1 PSTPIP1 ATG12 CD4 UBE2L6 RPS6KA5 MAPKAPK2 CD14 AIM2 LY86 ATG5 ISG15 IKBKE CDK1 +REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN NUP50 NUPL2 NUP35 NUP205 NUP210 NUP188 NUP62 GCK GCKR NUP43 NUP88 NUP54 NUP133 NUP107 RANBP2 TPR NUP37 NUP85 NUP214 AAAS SEH1L RAE1 NUP155 NUP93 NUPL1 POM121 NUP153 +REACTOME_MITOTIC_PROMETAPHASE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MITOTIC_PROMETAPHASE STAG1 NDC80 CENPA CENPC1 NUDC STAG2 KIF2C ZWINT PMF1 SPC24 SGOL2 SGOL1 SKA1 MAPRE1 CLASP1 ITGB3BP CENPI AHCTF1 NSL1 BIRC5 SKA2 NUP43 INCENP APITD1 KIF2A CENPP MAD2L1 PAFAH1B1 PLK1 ERCC6L CCDC99 PPP1CC ZWILCH CDCA8 PPP2CA PPP2CB CENPQ PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E NUP133 CENPN RCC2 CASC5 NUP107 SPC25 TAOK1 RAD21 RANBP2 RANGAP1 RPS27 CLIP1 SEC13 CENPK CENPH BUB1 BUB1B SKA2L XPO1 MIS12 CENPM NUP37 CENPO MLF1IP NUP85 DSN1 CENPT B9D2 NDEL1 SEH1L KIF18A SMC1A NUF2 MAD1L1 KIF2B SMC3 CENPL ZW10 BUB3 AURKB KNTC1 CKAP5 CDC20 +REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B ANAPC10 UBE2C CDC26 ANAPC2 ANAPC4 ANAPC5 ANAPC7 ANAPC11 RPS27A ANAPC1 LOC647654 LOC649620 LOC650621 LOC651763 RPS27AP11 CDC26P1 LOC730594 UBA52 UBE2D1 UBE2E1 CDC23 CDC16 CCNB1 CDK1 CDC20 CDC27 +REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 PSMD14 PSMA8 PSME4 FBXO5 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RPS27A SKP1 LOC652826 RPS27AP11 UBA52 CUL1 BTRC PSMF1 PSMD6 CDC20 +REACTOME_LIPOPROTEIN_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_LIPOPROTEIN_METABOLISM CETP APOA5 ABCA1 A2M ALB LDLRAP1 HSPG2 APOA1 APOA2 APOB APOC2 APOC3 APOE LCAT LDLR LIPC LPA LPL MTTP P4HB SAR1B PLTP SDC1 BMP1 CUBN AMN SCARB1 ABCG1 +REACTOME_G1_S_SPECIFIC_TRANSCRIPTION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G1_S_SPECIFIC_TRANSCRIPTION DHFR E2F1 FBXO5 LOC441488 ORC1 PCNA POLA1 RRM2 DHFRP1 TFDP1 TK2 TYMS CDT1 CDC45 CCNA1 CCNE1 CDK1 CDC6 CDC25A +REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS AP1M2 AP2M1 AP1S1 AP2S1 AP2A1 AP2A2 AP1B1 AP2B1 AP1G1 DOCK2 FYN HCK HLA-A ARF1 LCK PAK2 ATP6V1H PACS1 B2M RAC1 HLA-K AP1S2 AP1M1 CD247 CD4 CD8B CD28 ELMO1 +REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT APOA5 LDLRAP1 HSPG2 APOA1 APOA2 APOB APOC2 APOC3 APOE LDLR LIPC LPL MTTP P4HB SAR1B SDC1 +REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX CDK8 CDK9 STUB1 CDKN2B STRAP PARP1 E2F4 E2F5 FKBP1A ARHGEF18 PPP1R15A WWTR1 HDAC1 JUNB RHOA SMAD2 SMAD3 SMAD4 SMAD7 MEN1 LOC441488 MYC FURIN SERPINE1 F11R PARD6A UCHL5 TRIM33 PPM1A PPP1CA PPP1CB PPP1CC PRKCZ PARD3 PMEPA1 SMURF1 CGN RBL1 TGIF2 RPS27A SMURF2 SKI SKIL SP1 TFDP1 TGFB1 TGFBR1 TGFBR2 TGIF1 RPS27AP11 UBA52 LOC731429 UBE2D1 UBE2D3 XPO1 USP9X CCNC CCNT1 CCNT2 MTMR4 ZFYVE9 NCOR1 NCOR2 +REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE ANAPC10 UBE2C CDC26 ANAPC2 ANAPC4 ANAPC5 ANAPC7 ANAPC11 ANAPC1 LOC647654 LOC649620 LOC650621 LOC651763 CDC26P1 LOC730594 UBE2D1 UBE2E1 CDC14A CDC23 CDC16 CDC20 CDC27 +REACTOME_ACTIVATED_TLR4_SIGNALLING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATED_TLR4_SIGNALLING TLR6 NOD1 TAB1 IRAK3 TIRAP CHUK CREB1 ATF2 MAPK14 TICAM1 AGER DUSP3 DUSP4 DUSP6 DUSP7 ELK1 TAB2 FOS LY96 PELI3 TAB3 TBK1 HMGB1 APP TICAM2 IKBKB IRAK1 IRAK2 IRF3 IRF7 JUN TMEM189-UBE2V1 MEF2A MEF2C MAP3K1 MYD88 ATF1 NFKB2 NFKBIA NFKBIB IRAK4 ECSIT PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D MAPK1 MAPK3 MAPK7 MAPK8 MAPK11 MAPK9 MAPK10 MAP2K1 MAP2K2 MAP2K3 MAP2K6 MAP2K7 PELI2 PELI1 SIGIRR RELA RPS6KA1 RPS6KA2 RPS6KA3 RPS27A S100A12 S100B SAA1 NOD2 MAP2K4 LOC650832 MAP3K7 BTK TLR1 TLR2 TLR3 TLR4 TRAF3 TRAF6 RPS27AP11 UBA52 UBE2N MAPKAPK3 IKBKG RIPK1 RIPK2 RPS6KA5 MAPKAPK2 CD14 IKBKE CDK1 +REACTOME_IMMUNE_SYSTEM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_IMMUNE_SYSTEM AKT3 TANK AP1M2 UBA2 SAE1 HUWE1 KIF20A ACTR1B ACTR1A RASGRP1 RNF41 PSMD14 CD96 RASGRP2 CDKN1A CDKN1B STUB1 LILRB2 ADAR TLR6 IRF9 NOD1 ANAPC10 IFITM3 RAPGEF3 ARIH2 SEC24B TAB1 UBE2E3 SEC23A LRRC41 ATG7 DCTN2 IFITM2 RBCK1 TXNIP CD226 DCTN6 CNPY3 MASP2 CTSC NUP50 LILRB1 HCST CFHR3 MALT1 SEC61B LILRB5 KIF2C LILRB4 LILRA1 LILRB3 RIPK3 WWP1 UBE2C RAPGEF4 NUPL2 CD160 IRAK3 DCTN3 USP18 TRIM9 NLRP3 TIRAP CHUK OSBPL1A FBXO17 GBP4 GBP5 CISH THEM4 DEFB118 AP2M1 AP1S1 AP2S1 UBE2J2 PIK3AP1 AMICA1 CLTA CLTC LRR1 CCR2 CCR6 FBXO27 ASB17 NUP35 CD200R1 MAP3K8 RAET1E CR1 CREB1 ATF2 CREBBP CRK CRKL CRP ASB11 ASB5 ASB6 ASB7 ASB8 ASB9 DEFB104A DYNLL2 UBE2F DEFB127 DEFB129 ASB15 ASB12 MAPK14 PSMA8 CSF2 CSF2RA CSF2RB CSH1 LOC144383 CSK KLC3 TICAM1 UBE2U CTLA4 CTSB CTSD CTSH CTSK CTSL1 CTSL2 DTX3L BTLA CTSO CTSS CXADR CYBA CYBB CYLD AP2A1 CD55 AP2A2 AP1B1 AP2B1 GBP6 DCTN1 AP1G1 DDOST DEFA1 DEFA3 DEFA4 DEFA5 DEFA6 DEFB1 DEFB4A CFD DNM1 AGER DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI2 DNM2 DUSP3 DUSP4 DUSP6 DUSP7 EGR1 UBR1 EIF4A1 EIF4A2 EIF4E EIF4G1 EIF4G2 ELK1 EP300 AKT1 AKT2 PTK2B FCGR1A FCGR1B FCGR2B FCGR3A RNF182 NLRP1 SEC31A UBOX5 KLRK1 KIFAP3 TRIM32 FOXO1 FOXO3 RAP1GAP2 TAB2 NUP205 FLNB PSME4 NUP210 PHLPP1 FBXW11 UBR2 ICOSLG UBR4 SEC61G NUP188 FOS DDX58 MKRN1 NUP62 LY96 KIF4A PANX1 DEFB105A DEFB106A DEFB107A DEFB108B DEFB110 DEFB112 DEFB113 DEFB114 DEFB115 DEFB116 DEFB119 DEFB121 DEFB123 DEFB124 DEFB125 DEFB128 DEFB130 CDC26 PELI3 MTOR RICTOR FYB FYN IFI6 RNF144B UNC93B6 TAB3 RASGRP3 ARIH1 ANAPC13 RCHY1 SH2B1 DAK WSB1 KIF26A FBXO2 FBXW8 FBXO6 FBXO4 FBXO3 GBP1 GBP2 GH1 GH2 GHR LAT KLHL20 UBE2S KIF4B GRB2 RAPGEF1 PYCARD TBK1 CD274 RACGAP1 PDIA3 GSK3A BLNK ICOS ANAPC2 SEC61A1 ANAPC4 SH3KBP1 HCK CFH HGF PIK3R4 UBE2K HLA-A HLA-B HLA-C HLA-DMA HLA-DMB HLA-DOA HLA-DOB HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DRB1 HLA-DRB3 HLA-DRB5 HLA-F HLA-G HMGB1 NR4A1 EIF4E3 HRAS BIRC2 BIRC3 HSPA5 HSP90AB1 ICAM1 ICAM2 ICAM3 ICAM4 IRF8 CFI IFI27 IFI35 IFIT2 IFIT1 IFIT3 IFNA1 IFNA2 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNA10 IFNA14 IFNA16 IFNA17 IFNA21 IFNAR1 IFNAR2 IFNB1 IFNG IFNGR1 IFNGR2 NUP43 APP TICAM2 IKBKB IL1A IL1B IL1R1 IL1RAP IL1RN IL2 IL2RA IL2RB IL2RG IL3 IL3RA IL5 IL5RA IL6 IL6R IL6ST IL7 IL7R IL18 INPPL1 IRAK1 IRAK2 IRF1 IRF2 IRF3 IRF4 IRF5 IRF6 IRF7 IRS1 ISG20 ITGAL ITGAV ITGB1 ITGB2 ITGB5 ITGB7 ITK ITPR2 ITPR3 JAK1 JAK2 JAK3 JUN ARF1 KIF2A KIF3C KIF5A KIF5B KIR2DL1 KIR2DL2 KIR2DL3 KIR2DL4 KIR2DS1 KIR2DS2 KIR3DL1 KIR3DL2 KLRC1 KLRD1 KLC1 KIF11 KIF22 KPNA1 KPNB1 KPNA2 KPNA3 KPNA4 KPNA5 KRAS TMEM189-UBE2V1 GBP7 LBP LCK LCP2 LGALS3 DEFB132 LNPEP UNC93B2 CD180 LYN DEFB103A MBL2 ART1 CD46 MDM2 MEF2A MEF2C MEFV MAP3K1 MAP3K3 CIITA FOXO4 MRC1 LOC441019 MT2A TRIM37 MX1 MX2 MYD88 ATF1 NCAM1 NCF2 NCF4 NCK1 NEDD4 NFKB2 NFKBIA NFKBIB NFKBIE NRAS NUP88 OAS1 OAS2 OAS3 P2RX7 DEFB107B DEFB104B DEFB106B DEFB105B CD207 PAK1 PAK2 PARK2 TRAT1 PCBP2 SAR1B ASB3 IRAK4 DCTN4 HERC5 TLR7 ECSIT TLR8 PDCD1 ANAPC5 ANAPC7 RNF138 IP6K2 UBE2J1 EVL ANAPC11 UBE2D4 DYNC2LI1 ASB1 ASB4 ASB2 PDPK1 ERAP1 PIK3C3 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIN1 PLCG1 PLCG2 NUP54 PML TLR9 TOLLIP XAF1 CTSA UBE2R2 RNF125 PPM1B DET1 PPP2CA PPP2CB SEC61A2 PPP2R1A RNF220 PPP2R1B UBA6 PPP2R5A PPP2R5B PPP2R5C PPP2R5D UBE2W PPP2R5E FBXW7 TRIM36 UBE2Q1 OTUD5 PRKACA PRKACB PRKACG ENAH NUP133 PRKCB PRKCD PAG1 PRKCQ PRKCSH DEFB103B PRKG1 MAPK1 MAPK3 KLHL9 MAPK7 MAPK8 MAPK11 MAPK9 MAPK10 MAPK13 MAP2K1 MAP2K2 MAP2K3 MAP2K6 MAP2K7 EIF2AK2 PRL PRLR CRTAM PROS1 LGMN PRSS2 MASP1 B2M PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 KIF15 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 NUP107 PSMD7 PSMD8 PSMD9 SMURF1 PSMD10 PELI2 PELI1 PSMD11 PSMD12 PSMD13 BAD PSME1 PSME2 PTAFR PTEN MAVS PTPN1 PTPN2 TRIB3 PTPN6 PTPRC PVR PVRL2 NLRC4 RAC1 RAF1 RANBP2 RAP1A RAP1B RAP1GAP SIGIRR BCL2 REL RELA BCL2L1 RNASEL RNF4 RNF6 DEFB135 DEFB136 DEFB134 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KB2 RPS27A S100A12 S100B SAA1 CFB MAPK12 RNF123 UBE2O SEC13 BLK SELL NOD2 IFIH1 ZFYVE20 MAP2K4 CARD9 BLMH PJA1 MLST8 RNF25 LOC644006 DEFB131 TCEB1P3 LOC644816 SH3GL2 SHC1 UBE2HP1 LOC646626 ANAPC1 LOC646981 SMURF2 LOC647654 KLC2 LOC648998 SIPA1 LOC649620 HLA-K LOC649891 SKP1 SKP2 LOC650621 LOC650832 LOC651536 LOC651763 LOC652578 LOC652626 UBE2Z LOC652826 LOC653879 SOS1 SP100 SPTBN2 SRC TRIM21 STAT1 STAT2 STAT3 STAT5A STAT5B STIM1 SYK ADAM17 MAP3K7 TAP1 TAP2 TCEB1 TCEB2 BTK TEC TLR1 TLR2 TLR3 TLR4 TLR5 C1QA TNFAIP3 C1QB C1QC C1S C2 TPP2 TPR C3 HSP90B1 TRAF2 TRAF3 TRAF6 C4A C4BPA TSC2 C4BPB C5 DEFA1B DEFB4B RPS27AP11 C6 LOC729120 TXN LOC729523 TYK2 CDC26P1 C7 LOC730418 TYROBP LOC730594 C8A LOC731049 LOC731066 UBA52 LOC731292 LOC731429 UBA1 UBA7 UBE2A LOC731949 C8B UBE2B UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2G1 UBE2G2 UBE2H C8G UBE2L3 UBE2N UBE2V2 UBE3A SUMO1 C9 VASP VAV1 VCAM1 VHL WAS YES1 YWHAB YWHAZ ZAP70 ZBTB16 TRIM25 IL1R2 MAPKAPK3 RAB7A NUP37 MAPKAP1 DHX58 TNIP2 ULBP3 HECTD3 DYNC2H1 NLRX1 ASB13 UBA5 NUP85 CALM1 SIKE1 SPSB1 RNF34 NUP214 ULBP2 ULBP1 PDCD1LG2 CALM2 CUL5 CALM3 AAAS ZBP1 CALR GAN CAMK2A TRIM11 CAMK2B UNC93B1 DEFB126 CAMK2D TLR10 SEH1L KIF18A CANX CAPZA1 CAPZA2 CASP1 CASP2 RILP CASP4 CASP8 EEA1 NLRC5 CASP9 RNF135 CASP10 AKT1S1 CARD11 DCTN5 CUL3 CUL2 CUL1 KIF2B TRIM63 SPSB2 RAE1 ORAI1 PIK3R3 IKBKG IFITM1 PIAS1 OASL SOCS1 DYNLL1 IRS2 CBL EIF4G3 CBLB CDC23 CTSF RIPK1 TNFRSF14 RIPK2 FADD SOCS2 SQSTM1 CDC16 TAX1BP1 AP1S2 AP1M1 BCL10 HERC2 BTRC UBE3B KLC4 MAP3K14 SOCS3 KLHL13 UBA3 UBE2M PSTPIP1 LRSAM1 ATG12 CD3D CD3E CD3G CD247 CD4 SPSB4 UBE2L6 CD8A RPS6KA5 ASB16 CD8B MAPKAPK2 CD14 UBE2Q2 CD19 TRIP12 UBE4A FBXO44 KIF3B CD28 GRAP2 CD80 CD86 AIM2 LY86 CD34 EIF4E2 ATG5 CD36 PSMF1 KIF23 NPEPPS CD40 CD40LG CD44 NUP155 SEC24C ISG15 IKBKE DZIP3 NUP93 UBE3C CD74 CD79A VPRBP CD79B CD81 EIF4A3 KEAP1 NUPL1 CUL7 CDK1 GAB2 PSMD6 PJA2 SEC24D POM121 MRC2 CDC20 CDC27 CDC34 NUP153 RBX1 CDC42 CDH1 +REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION CCR5 LOC128192 LOC131691 PPIAP8 PPIA LOC643997 PPIAP22 LOC654188 CXCR4 CD4 +REACTOME_PHOSPHORYLATION_OF_THE_APC_C http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PHOSPHORYLATION_OF_THE_APC_C ANAPC10 UBE2C CDC26 ANAPC2 ANAPC4 ANAPC5 ANAPC7 ANAPC11 PLK1 ANAPC1 LOC647654 LOC649620 LOC650621 LOC651763 CDC26P1 LOC730594 UBE2D1 UBE2E1 CDC23 CDC16 CCNB1 CDK1 CDC27 +REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES BPNT1 SULT4A1 SULT1C4 SULT1B1 SULT1A4 SULT1E1 SULT1A2 SULT1A1 SULT1A3 SULT1C2 SULT2B1 SULT2A1 PAPSS2 PAPSS1 +REACTOME_INTEGRATION_OF_PROVIRUS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTEGRATION_OF_PROVIRUS PSIP1 LOC128192 LOC131691 XRCC6 HMGA1 PPIAP8 LOC389901 LIG4 PPIA LOC643997 LOC645870 PPIAP22 LOC654188 XRCC4 XRCC5 BANF1 +REACTOME_GLUTATHIONE_CONJUGATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLUTATHIONE_CONJUGATION GSTO2 GSTA5 GGT1 GGT7 GGT5 OPLAH GCLC GCLM GSS GSTA1 GSTA2 GSTA3 GSTA4 GSTM1 GSTM4 GSTM5 GSTP1 MGST1 MGST2 MGST3 CNDP2 GGCT GSTO1 +REACTOME_COMPLEMENT_CASCADE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_COMPLEMENT_CASCADE MASP2 CFHR3 CR1 CRP CD55 CFD CFH CFI MBL2 CD46 PROS1 MASP1 CFB LOC651536 LOC653879 C1QA C1QB C1QC C1S C2 C3 C4A C4BPA C4BPB C5 C6 C7 C8A LOC731066 C8B C8G C9 +REACTOME_PHASE_II_CONJUGATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PHASE_II_CONJUGATION NAT2 GLYAT BPNT1 UGT2B11 UGT2A1 ACSM1 GSTO2 COMT CYP1A2 AHCY GSTA5 SLC35D1 SULT4A1 GGT1 GGT7 GGT5 OPLAH SULT1C4 SULT1B1 GCLC GCLM MAT2B GSS GSTA1 GSTA2 GSTA3 GSTA4 GSTM1 GSTM4 GSTM5 GSTP1 ACSM2B MAT1A MAT2A MGST1 MGST2 MGST3 SULT1A4 MTR NNMT UGT2B28 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9 UGT1A4 UGT1A1 UGT1A3 CNDP2 LOC648338 SULT1E1 SULT1A2 SULT1A1 SULT1A3 SULT1C2 SULT2B1 SULT2A1 TPMT UGDH UGP2 UGT2B4 UGT2B7 UGT2B10 UGT2B17 GGCT NAT1 PAPSS2 PAPSS1 GSTO1 +REACTOME_MTORC1_MEDIATED_SIGNALLING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MTORC1_MEDIATED_SIGNALLING EIF4B EIF4E EIF4EBP1 EIF4G1 MTOR EEF2K RPTOR RHEB RPS6 RPS6KB1 MLST8 +REACTOME_TOLL_RECEPTOR_CASCADES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TOLL_RECEPTOR_CASCADES TLR6 NOD1 TAB1 CNPY3 IRAK3 TIRAP CHUK CREB1 ATF2 MAPK14 TICAM1 CTSB CTSK CTSL1 CTSS DNM1 AGER DNM2 DUSP3 DUSP4 DUSP6 DUSP7 ELK1 TAB2 FOS LY96 PELI3 UNC93B6 TAB3 TBK1 PIK3R4 HMGB1 APP TICAM2 IKBKB IRAK1 IRAK2 IRF3 IRF7 JUN TMEM189-UBE2V1 LBP UNC93B2 CD180 MEF2A MEF2C MAP3K1 MYD88 ATF1 NFKB2 NFKBIA NFKBIB IRAK4 TLR7 ECSIT TLR8 PIK3C3 PLCG2 TLR9 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D MAPK1 MAPK3 MAPK7 MAPK8 MAPK11 MAPK9 MAPK10 MAP2K1 MAP2K2 MAP2K3 MAP2K6 MAP2K7 LGMN PELI2 PELI1 SIGIRR RELA RPS6KA1 RPS6KA2 RPS6KA3 RPS27A S100A12 S100B SAA1 NOD2 ZFYVE20 MAP2K4 LOC650832 MAP3K7 BTK TLR1 TLR2 TLR3 TLR4 TLR5 HSP90B1 TRAF3 TRAF6 RPS27AP11 UBA52 UBE2N MAPKAPK3 UNC93B1 TLR10 EEA1 IKBKG RIPK1 RIPK2 RPS6KA5 MAPKAPK2 CD14 LY86 IKBKE CDK1 +REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS BCL2L11 DYNLL2 E2F1 AKT1 BBC3 LOC441488 PMAIP1 PPP3R1 MAPK8 BAD BCL2 BID TFDP1 TP53 YWHAB DYNLL1 BMF +REACTOME_GLUCOSE_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GLUCOSE_METABOLISM SLC25A13 SLC25A10 AGL ENO1 ENO2 ENO3 FBP1 ALDOA ALDOB ALDOC GAPDH GBE1 GAPDHS GOT1 GOT2 GPI GYG1 GYS1 GYS2 MDH1 MDH2 PC PCK1 PCK2 PFKFB1 PFKFB2 PFKFB3 PFKFB4 PFKL PFKM PFKP PGAM1 PGAM2 PGK1 PGM1 PHKA1 PHKA2 PHKB PHKG1 PHKG2 PKLR PKM2 PPP2CA PPP2CB PPP2R1A PPP2R1B PGM2 PPP2R5D PRKACA PRKACB PRKACG PYGB PYGL PYGM LOC642969 PHKA1P1 LOC650556 SLC25A1 TPI1 TPI1P1 LOC730418 UGP2 CALM1 CALM2 CALM3 SLC25A11 SLC25A12 FBP2 GYG2 +REACTOME_RNA_POL_III_CHAIN_ELONGATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_III_CHAIN_ELONGATION POLR3F POLR3C POLR3A LZTS1 POLR3H POLR1D POLR3K POLR2E POLR2F POLR2H POLR2K POLR2L POLR3B POLR3E POLR3D POLR3GL POLR1C +REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS KCNH8 KCNV2 KCNG3 KCNH4 KCNH3 KCNG2 KCNV1 KCNH5 KCNA1 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNA10 KCNB1 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNG1 KCNH1 KCNH2 KCNQ1 KCNQ2 KCNQ3 KCNS1 KCNS2 KCNS3 KCNQ5 KCNAB1 KCNH6 KCNAB2 KCNH7 KCNQ4 KCNAB3 KCNG4 KCNB2 +REACTOME_ADAPTIVE_IMMUNE_SYSTEM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ADAPTIVE_IMMUNE_SYSTEM AKT3 AP1M2 UBA2 SAE1 HUWE1 KIF20A ACTR1B ACTR1A RASGRP1 RNF41 PSMD14 CD96 RASGRP2 CDKN1A CDKN1B STUB1 LILRB2 ANAPC10 RAPGEF3 ARIH2 SEC24B UBE2E3 SEC23A LRRC41 ATG7 DCTN2 RBCK1 CD226 DCTN6 CTSC LILRB1 HCST MALT1 SEC61B LILRB5 KIF2C LILRB4 LILRA1 LILRB3 WWP1 UBE2C RAPGEF4 CD160 DCTN3 TRIM9 CHUK OSBPL1A FBXO17 THEM4 AP2M1 AP1S1 AP2S1 UBE2J2 PIK3AP1 AMICA1 CLTA CLTC LRR1 FBXO27 ASB17 CD200R1 MAP3K8 RAET1E CREB1 ASB11 ASB5 ASB6 ASB7 ASB8 ASB9 DYNLL2 UBE2F ASB15 ASB12 PSMA8 CSK KLC3 UBE2U CTLA4 CTSB CTSD CTSH CTSK CTSL1 CTSL2 DTX3L BTLA CTSO CTSS CXADR CYBA CYBB AP2A1 AP2A2 AP1B1 AP2B1 DCTN1 AP1G1 DNM1 DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI2 DNM2 UBR1 AKT1 AKT2 FCGR1A FCGR1B FCGR2B FCGR3A RNF182 SEC31A UBOX5 KLRK1 KIFAP3 TRIM32 FOXO1 FOXO3 RAP1GAP2 TAB2 PSME4 PHLPP1 FBXW11 UBR2 ICOSLG UBR4 SEC61G MKRN1 KIF4A CDC26 MTOR RICTOR FYB FYN RNF144B RASGRP3 ANAPC13 RCHY1 WSB1 KIF26A FBXO2 FBXW8 FBXO6 FBXO4 FBXO3 LAT KLHL20 UBE2S KIF4B GRB2 CD274 RACGAP1 PDIA3 GSK3A BLNK ICOS ANAPC2 SEC61A1 ANAPC4 SH3KBP1 UBE2K HLA-A HLA-B HLA-C HLA-DMA HLA-DMB HLA-DOA HLA-DOB HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DRB1 HLA-DRB3 HLA-DRB5 HLA-F HLA-G NR4A1 HRAS HSPA5 ICAM1 ICAM2 ICAM3 ICAM4 IKBKB ITGAL ITGAV ITGB1 ITGB2 ITGB5 ITGB7 ITK ITPR2 ITPR3 ARF1 KIF2A KIF3C KIF5A KIF5B KIR2DL1 KIR2DL2 KIR2DL3 KIR2DL4 KIR2DS1 KIR2DS2 KIR3DL1 KIR3DL2 KLRC1 KLRD1 KLC1 KIF11 KIF22 KRAS TMEM189-UBE2V1 LCK LCP2 LNPEP LYN MDM2 FOXO4 MRC1 TRIM37 NCF2 NCF4 NCK1 NEDD4 NFKBIA NFKBIB NFKBIE NRAS CD207 PAK1 PAK2 PARK2 TRAT1 SAR1B ASB3 DCTN4 PDCD1 ANAPC5 ANAPC7 RNF138 UBE2J1 EVL ANAPC11 UBE2D4 DYNC2LI1 ASB1 ASB4 ASB2 PDPK1 ERAP1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PLCG1 PLCG2 CTSA UBE2R2 DET1 PPP2CA PPP2CB SEC61A2 PPP2R1A RNF220 PPP2R1B UBA6 PPP2R5A PPP2R5B PPP2R5C PPP2R5D UBE2W PPP2R5E FBXW7 TRIM36 UBE2Q1 PRKACA PRKACB PRKACG ENAH PRKCB PAG1 PRKCQ PRKG1 KLHL9 CRTAM LGMN B2M PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 KIF15 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 SMURF1 PSMD10 PSMD11 PSMD12 PSMD13 BAD PSME1 PSME2 PTEN TRIB3 PTPN6 PTPRC PVR PVRL2 RAC1 RAF1 RAP1A RAP1B RAP1GAP REL RELA RNF4 RNF6 RPS6KB2 RPS27A RNF123 UBE2O SEC13 BLK SELL BLMH PJA1 MLST8 RNF25 LOC644006 TCEB1P3 SH3GL2 SHC1 UBE2HP1 LOC646626 ANAPC1 SMURF2 LOC647654 KLC2 LOC648998 SIPA1 LOC649620 HLA-K SKP1 SKP2 LOC650621 LOC651536 LOC651763 LOC652578 LOC652626 UBE2Z LOC652826 LOC653879 SOS1 SPTBN2 SRC TRIM21 STIM1 SYK MAP3K7 TAP1 TAP2 TCEB1 TCEB2 BTK TPP2 C3 TRAF6 TSC2 RPS27AP11 LOC729120 CDC26P1 LOC730418 TYROBP LOC730594 LOC731049 LOC731066 UBA52 LOC731292 LOC731429 UBA1 UBA7 UBE2A UBE2B UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2G1 UBE2G2 UBE2H UBE2L3 UBE2N UBE2V2 UBE3A VASP VAV1 VCAM1 VHL WAS YES1 YWHAB YWHAZ ZAP70 ZBTB16 RAB7A MAPKAP1 ULBP3 HECTD3 DYNC2H1 ASB13 UBA5 CALM1 SPSB1 RNF34 ULBP2 ULBP1 PDCD1LG2 CALM2 CUL5 CALM3 CALR GAN TRIM11 KIF18A CANX RILP CASP9 AKT1S1 CARD11 DCTN5 CUL3 CUL2 CUL1 KIF2B TRIM63 SPSB2 ORAI1 PIK3R3 IKBKG IFITM1 SOCS1 DYNLL1 CBL CBLB CDC23 CTSF TNFRSF14 RIPK2 CDC16 AP1S2 AP1M1 BCL10 HERC2 BTRC UBE3B KLC4 MAP3K14 SOCS3 KLHL13 UBA3 UBE2M LRSAM1 CD3D CD3E CD3G CD247 CD4 SPSB4 UBE2L6 CD8A ASB16 CD8B UBE2Q2 CD19 TRIP12 UBE4A FBXO44 KIF3B CD28 GRAP2 CD80 CD86 CD34 CD36 PSMF1 KIF23 NPEPPS CD40 CD40LG SEC24C DZIP3 UBE3C CD74 CD79A VPRBP CD79B CD81 KEAP1 CUL7 PSMD6 PJA2 SEC24D MRC2 CDC20 CDC27 CDC34 RBX1 CDC42 CDH1 +REACTOME_NOD1_2_SIGNALING_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NOD1_2_SIGNALING_PATHWAY NOD1 TAB1 CHUK MAPK14 CYLD TAB2 TAB3 BIRC2 BIRC3 IKBKB IRAK1 IRAK2 TMEM189-UBE2V1 MAPK11 MAPK13 MAP2K6 MAPK12 NOD2 CARD9 MAP3K7 TNFAIP3 TRAF6 UBE2N CASP1 CASP2 CASP4 CASP8 CASP9 IKBKG RIPK2 +REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM ADAR IRF9 NOD1 IFITM3 TAB1 IFITM2 NUP50 NUPL2 IRAK3 USP18 CHUK GBP4 GBP5 CISH NUP35 MAP3K8 CRK CRKL CSF2 CSF2RA CSF2RB CSH1 LOC144383 GBP6 EGR1 EIF4A1 EIF4A2 EIF4E EIF4G1 EIF4G2 PTK2B FCGR1A FCGR1B TAB2 NUP205 FLNB NUP210 NUP188 DDX58 NUP62 PELI3 FYN IFI6 TAB3 ARIH1 SH2B1 GBP1 GBP2 GH1 GH2 GHR GRB2 RAPGEF1 BLNK HCK HGF HLA-A HLA-B HLA-C HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DRB1 HLA-DRB3 HLA-DRB5 HLA-F HLA-G EIF4E3 HRAS ICAM1 IRF8 IFI27 IFI35 IFIT2 IFIT1 IFIT3 IFNA1 IFNA2 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNA10 IFNA14 IFNA16 IFNA17 IFNA21 IFNAR1 IFNAR2 IFNB1 IFNG IFNGR1 IFNGR2 NUP43 IKBKB IL1A IL1B IL1R1 IL1RAP IL1RN IL2 IL2RA IL2RB IL2RG IL3 IL3RA IL5 IL5RA IL6 IL6R IL6ST IL7 IL7R IL18 INPPL1 IRAK1 IRAK2 IRF1 IRF2 IRF3 IRF4 IRF5 IRF6 IRF7 IRS1 ISG20 JAK1 JAK2 JAK3 KPNA1 KPNB1 KPNA2 KPNA3 KPNA4 KPNA5 KRAS TMEM189-UBE2V1 GBP7 LCK LYN MAP3K3 CIITA LOC441019 MT2A MX1 MX2 MYD88 NCAM1 NEDD4 NFKB2 NRAS NUP88 OAS1 OAS2 OAS3 IRAK4 HERC5 IP6K2 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIN1 PLCG1 NUP54 PML TOLLIP XAF1 PPM1B PRKACB NUP133 PRKCD MAPK1 MAPK3 MAP2K1 MAP2K2 MAP2K6 EIF2AK2 PRL PRLR B2M PSMB8 NUP107 PELI2 PELI1 PTAFR PTPN1 PTPN2 PTPN6 RAF1 RANBP2 RELA RNASEL RPS27A NOD2 MAP2K4 SHC1 LOC646981 HLA-K LOC649891 SKP1 SOS1 SP100 STAT1 STAT2 STAT3 STAT5A STAT5B SYK ADAM17 MAP3K7 TEC TPR TRAF6 RPS27AP11 TYK2 UBA52 UBA7 UBE2E1 UBE2N SUMO1 VAV1 VCAM1 YES1 YWHAB YWHAZ TRIM25 IL1R2 NUP37 TNIP2 NUP85 NUP214 AAAS CAMK2A CAMK2B CAMK2D SEH1L CASP1 CUL1 RAE1 PIK3R3 IKBKG IFITM1 PIAS1 OASL SOCS1 IRS2 CBL EIF4G3 RIPK2 SOCS2 SQSTM1 BTRC SOCS3 UBE2L6 EIF4E2 CD44 NUP155 ISG15 NUP93 EIF4A3 NUPL1 CDK1 GAB2 POM121 NUP153 RBX1 +REACTOME_MEIOTIC_SYNAPSIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_MEIOTIC_SYNAPSIS STAG1 SYCP2 STAG3 STAG2 DIDO1 HIST4H4 HIST3H2BB SYNE2 SYNE1 HIST1H2BA SUN2 POT1 TINF2 SMC1B HIST1H2AE HIST1H2AD H2AFX H2AFZ HIST1H2BD HIST1H2BB HSPA2 LMNA LMNB1 SYCP3 TERF2IP ATR HIST2H4B TEX12 RAD21 LOC648152 ACD LOC651921 BRCA1 SYCP1 TERF1 TERF2 HIST2H2AA4 UBE2I SMC1A HIST3H3 HIST1H4I HIST1H2AJ HIST1H2AC HIST1H2AB HIST2H2AA3 HIST2H2AC HIST1H2BG HIST1H2BL HIST1H2BN HIST1H2BM HIST1H2BF HIST1H2BE HIST1H2BH HIST1H2BI HIST1H2BC HIST1H2BO HIST2H2BE HIST1H4A HIST1H4D HIST1H4F HIST1H4K HIST1H4J HIST1H4C HIST1H4H HIST1H4B HIST1H4E HIST1H4L HIST2H4A FKBP6 HIST1H2BK HIST1H2BJ SMC3 REC8 +REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC SEC24B SEC23A SEC31A PDIA3 HLA-A HLA-B HLA-C HLA-F HLA-G HSPA5 SAR1B ERAP1 B2M SEC13 HLA-K TAP1 TAP2 CALR CANX SEC24C SEC24D +REACTOME_THE_NLRP3_INFLAMMASOME http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_THE_NLRP3_INFLAMMASOME TXNIP NLRP3 PANX1 PYCARD HSP90AB1 APP MEFV P2RX7 LOC644816 TXN CASP1 PSTPIP1 +REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION UBA2 SAE1 HUWE1 RNF41 PSMD14 STUB1 ANAPC10 ARIH2 SEC24B UBE2E3 SEC23A LRRC41 ATG7 RBCK1 SEC61B WWP1 UBE2C TRIM9 FBXO17 UBE2J2 LRR1 FBXO27 ASB17 ASB11 ASB5 ASB6 ASB7 ASB8 ASB9 UBE2F ASB15 ASB12 PSMA8 UBE2U DTX3L CTSS CYBA CYBB UBR1 FCGR1A FCGR1B RNF182 SEC31A UBOX5 TRIM32 PSME4 FBXW11 UBR2 UBR4 SEC61G MKRN1 CDC26 RNF144B ANAPC13 RCHY1 WSB1 FBXO2 FBXW8 FBXO6 FBXO4 FBXO3 KLHL20 UBE2S PDIA3 ANAPC2 SEC61A1 ANAPC4 UBE2K HLA-A HLA-B HLA-C HLA-F HLA-G HSPA5 ITGAV ITGB5 TMEM189-UBE2V1 LNPEP MRC1 TRIM37 NCF2 NCF4 NEDD4 CD207 PARK2 SAR1B ASB3 ANAPC5 ANAPC7 RNF138 UBE2J1 ANAPC11 UBE2D4 ASB1 ASB4 ASB2 ERAP1 UBE2R2 DET1 SEC61A2 RNF220 UBA6 UBE2W FBXW7 TRIM36 UBE2Q1 KLHL9 B2M PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 SMURF1 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RNF4 RNF6 RPS27A RNF123 UBE2O SEC13 BLMH PJA1 RNF25 LOC644006 TCEB1P3 UBE2HP1 ANAPC1 SMURF2 LOC647654 LOC648998 LOC649620 HLA-K SKP1 SKP2 LOC650621 LOC651763 UBE2Z LOC652826 TRIM21 TAP1 TAP2 TCEB1 TCEB2 TPP2 RPS27AP11 CDC26P1 LOC730594 LOC731049 UBA52 LOC731429 UBA1 UBA7 UBE2A UBE2B UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2G1 UBE2G2 UBE2H UBE2L3 UBE2N UBE2V2 UBE3A VHL ZBTB16 HECTD3 ASB13 UBA5 SPSB1 RNF34 CUL5 CALR GAN TRIM11 CANX CUL3 CUL2 CUL1 TRIM63 SPSB2 SOCS1 CBLB CDC23 CDC16 HERC2 BTRC UBE3B SOCS3 KLHL13 UBA3 UBE2M LRSAM1 SPSB4 UBE2L6 ASB16 UBE2Q2 TRIP12 UBE4A FBXO44 CD36 PSMF1 NPEPPS SEC24C DZIP3 UBE3C VPRBP KEAP1 CUL7 PSMD6 PJA2 SEC24D MRC2 CDC20 CDC27 CDC34 RBX1 +REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX RNPS1 RPL35 RPL7AP27 EIF4G1 ETF1 FAU CASC3 NCBP2 SMG1 SMG6 SMG5 RPL13A GSPT2 RPL36 UPF2 PABPC1 RPL10P16 FAM153A RPL36P14 RPSAP12 RPS8P10 RPL7AP66 RPL10P9 RPS12P4 RPSA RPS26P10 RPL23AP2 MAGOH RPS12P22 RPL21P29 RPS26P35 NCBP1 RPL10A RPL26L1 PPP2CA PPP2R1A SMG8 PPP2R2A SMG9 RPL3 RPL3L RPL4 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL10 RPL11 RPL12 RPL13 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL23A RPL24 RPL26 RPL27 RPL30 RPL27A RPL28 RPL29 RPL31 RPL32 RPL34 RPL35A RPL37 RPL37A RPL38 RPL39 RPL41 RPL36A RPLP0 RPLP1 RPLP2 RPS2 RPS3 RPS3A RPS4X RPS4Y1 RPS5 RPS6 RPS7 RPS8 RPS9 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS18 RPS19 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS28 RPS29 RPL6P19 LOC641895 RPL36AP31 RPS29P3 RPS26P28 RPL36AP8 RPL26P22 LOC643446 RPS26P20 RPS15AP11 RPS26P50 RPL22P11 RPL17P6 RPS13P8 RPS28P4 RPL32P16 LOC646184 RPS28P7 RPL12P2 LOC647074 RPL23AP42 RPL5P1 RPL36AP51 LOC649602 RPS28P9 UPF3B UPF3A RPL34P27 LOC651825 LOC651894 LOC652607 RPL26P30 RPSAP9 RPL19P9 RPL21P119 RPL31P17 LOC653881 RPL31P31 RPL15P17 RPL23AP18 RPL26P24 RPL21P75 RPS27AP11 RPS26P7 RPL21P134 RPS26P25 RPS19P3 RPL36AP23 RPS18P10 RPL17P36 RPL36AP37 RPL21P16 RPL23AP74 RPS15P5 RPL23AP63 RPS10P9 LOC730343 RPS18P5 UBA52 RPL34P31 RPL14 RPL23 EIF4A3 SMG7 RBM8A +REACTOME_PIP3_ACTIVATES_AKT_SIGNALING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PIP3_ACTIVATES_AKT_SIGNALING AKT3 CDKN1A CDKN1B CHUK THEM4 CREB1 AKT1 AKT2 FOXO1 FOXO3 PHLPP1 MTOR RICTOR GSK3A NR4A1 MDM2 FOXO4 PDPK1 BAD PTEN TRIB3 RPS6KB2 MLST8 TSC2 LOC729120 LOC731292 MAPKAP1 CASP9 AKT1S1 +REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION UBA2 SAE1 HUWE1 RNF41 PSMD14 STUB1 ANAPC10 ARIH2 UBE2E3 LRRC41 ATG7 RBCK1 WWP1 UBE2C TRIM9 FBXO17 UBE2J2 LRR1 FBXO27 ASB17 ASB11 ASB5 ASB6 ASB7 ASB8 ASB9 UBE2F ASB15 ASB12 PSMA8 UBE2U DTX3L UBR1 RNF182 UBOX5 TRIM32 PSME4 FBXW11 UBR2 UBR4 MKRN1 CDC26 RNF144B ANAPC13 RCHY1 WSB1 FBXO2 FBXW8 FBXO6 FBXO4 FBXO3 KLHL20 UBE2S ANAPC2 ANAPC4 UBE2K TMEM189-UBE2V1 LNPEP TRIM37 NEDD4 PARK2 ASB3 ANAPC5 ANAPC7 RNF138 UBE2J1 ANAPC11 UBE2D4 ASB1 ASB4 ASB2 UBE2R2 DET1 RNF220 UBA6 UBE2W FBXW7 TRIM36 UBE2Q1 KLHL9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 SMURF1 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RNF4 RNF6 RPS27A RNF123 UBE2O BLMH PJA1 RNF25 LOC644006 TCEB1P3 UBE2HP1 ANAPC1 SMURF2 LOC647654 LOC649620 SKP1 SKP2 LOC650621 LOC651763 UBE2Z LOC652826 TRIM21 TCEB1 TCEB2 TPP2 RPS27AP11 CDC26P1 LOC730594 LOC731049 UBA52 LOC731429 UBA1 UBA7 UBE2A UBE2B UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2G1 UBE2G2 UBE2H UBE2L3 UBE2N UBE2V2 UBE3A VHL ZBTB16 HECTD3 ASB13 UBA5 SPSB1 RNF34 CUL5 GAN TRIM11 CUL3 CUL2 CUL1 TRIM63 SPSB2 SOCS1 CBLB CDC23 CDC16 HERC2 BTRC UBE3B SOCS3 KLHL13 UBA3 UBE2M LRSAM1 SPSB4 UBE2L6 ASB16 UBE2Q2 TRIP12 UBE4A FBXO44 PSMF1 NPEPPS DZIP3 UBE3C VPRBP KEAP1 CUL7 PSMD6 PJA2 CDC20 CDC27 CDC34 RBX1 +REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS KCNK7 KCNK18 KCNK1 KCNK2 KCNK3 KCNK4 KCNK9 KCNK10 KCNK13 KCNK16 KCNK17 KCNK6 +REACTOME_INFLAMMASOMES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INFLAMMASOMES TXNIP NLRP3 NLRP1 PANX1 PYCARD HSP90AB1 APP MEFV P2RX7 NLRC4 BCL2 BCL2L1 LOC644816 TXN CASP1 PSTPIP1 AIM2 +REACTOME_POTASSIUM_CHANNELS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_POTASSIUM_CHANNELS HCN4 ABCC9 KCNK7 KCNMB2 KCNH8 KCNV2 KCNG3 KCNH4 KCNH3 GABBR1 KCNG2 KCNV1 KCNMB3 KCNH5 KCNMB4 GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNGT1 GNGT2 KCNK18 HCN1 KCNA1 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNA10 KCNB1 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNG1 KCNH1 KCNH2 KCNJ1 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6 KCNJ8 KCNJ9 KCNJ10 KCNJ11 KCNJ12 KCNJ14 KCNJ15 KCNJ16 KCNK1 KCNK2 KCNK3 KCNMB1 KCNN1 KCNN2 KCNN3 KCNN4 KCNQ1 KCNQ2 KCNQ3 KCNS1 KCNS2 KCNS3 KCNK4 KCNK9 KCNK10 GNG2 GNG12 KCNQ5 KCNK13 HCN3 HCN2 ABCC8 KCNAB1 KCNH6 KCNK16 KCNAB2 KCNK17 KCNH7 KCNQ4 KCNAB3 KCNG4 KCNB2 GNG8 KCNK6 GABBR2 +REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS NOD1 TAB1 TXNIP NLRP3 CHUK MAPK14 CYLD NLRP1 TAB2 PANX1 TAB3 PYCARD BIRC2 BIRC3 HSP90AB1 APP IKBKB IRAK1 IRAK2 TMEM189-UBE2V1 MEFV P2RX7 MAPK11 MAPK13 MAP2K6 NLRC4 BCL2 BCL2L1 MAPK12 NOD2 CARD9 LOC644816 MAP3K7 TNFAIP3 TRAF6 TXN UBE2N CASP1 CASP2 CASP4 CASP8 CASP9 IKBKG RIPK2 PSTPIP1 AIM2 +REACTOME_INWARDLY_RECTIFYING_K_CHANNELS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INWARDLY_RECTIFYING_K_CHANNELS ABCC9 GABBR1 GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNGT1 GNGT2 KCNJ1 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6 KCNJ8 KCNJ9 KCNJ10 KCNJ11 KCNJ12 KCNJ14 KCNJ15 KCNJ16 GNG2 GNG12 ABCC8 GNG8 GABBR2 +REACTOME_AMYLOIDS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_AMYLOIDS HIST4H4 HIST2H3C HIST3H2BB CST3 FGA HIST1H2BA GSN HIST1H2AE HIST1H2AD H2AFX H2AFZ HIST1H2BD HIST1H2BB H3F3A H3F3B APCS HSPG2 HIST2H3A APOA1 IAPP H3F3AP5 APP INS LTF LYZ MFGE8 NPPA ODAM HIST2H4B PRL B2M SAA1 SEMG1 H3F3AP6 HIST2H3D SNCA TGFBI HIST2H2AA4 TTR LOC728320 LOC731820 CALCA HIST1H4I HIST1H2AJ HIST1H2AC HIST1H2AB HIST2H2AA3 HIST2H2AC HIST1H2BG HIST1H2BL HIST1H2BN HIST1H2BM HIST1H2BF HIST1H2BE HIST1H2BH HIST1H2BI HIST1H2BC HIST1H2BO HIST2H2BE HIST1H3A HIST1H3D HIST1H3C HIST1H3E HIST1H3I HIST1H3G HIST1H3J HIST1H3H HIST1H3B HIST1H4A HIST1H4D HIST1H4F HIST1H4K HIST1H4J HIST1H4C HIST1H4H HIST1H4B HIST1H4E HIST1H4L HIST2H4A HIST1H2BK HIST1H3F HIST1H2BJ ITM2B +REACTOME_PACKAGING_OF_TELOMERE_ENDS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PACKAGING_OF_TELOMERE_ENDS HIST4H4 HIST3H2BB HIST1H2BA POT1 TINF2 HIST1H2AE HIST1H2AD H2AFX H2AFZ HIST1H2BD HIST1H2BB TERF2IP HIST2H4B ACD TERF1 TERF2 HIST2H2AA4 HIST3H3 HIST1H4I HIST1H2AJ HIST1H2AC HIST1H2AB HIST2H2AA3 HIST2H2AC HIST1H2BG HIST1H2BL HIST1H2BN HIST1H2BM HIST1H2BF HIST1H2BE HIST1H2BH HIST1H2BI HIST1H2BC HIST1H2BO HIST2H2BE HIST1H4A HIST1H4D HIST1H4F HIST1H4K HIST1H4J HIST1H4C HIST1H4H HIST1H4B HIST1H4E HIST1H4L HIST2H4A HIST1H2BK HIST1H2BJ +REACTOME_TELOMERE_MAINTENANCE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TELOMERE_MAINTENANCE POLD3 RUVBL2 HIST4H4 HIST3H2BB DKC1 DNA2 FEN1 POLA2 HIST1H2BA POT1 TINF2 HIST1H2AE HIST1H2AD H2AFX H2AFZ HIST1H2BD HIST1H2BB LIG1 PCNA POLA1 POLD1 POLD2 POLE POLE2 TERF2IP WRAP53 HIST2H4B PRIM1 PRIM2 NHP2 POLD4 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 ACD TERF1 TERF2 TERT HIST2H2AA4 HIST3H3 HIST1H4I HIST1H2AJ HIST1H2AC HIST1H2AB HIST2H2AA3 HIST2H2AC HIST1H2BG HIST1H2BL HIST1H2BN HIST1H2BM HIST1H2BF HIST1H2BE HIST1H2BH HIST1H2BI HIST1H2BC HIST1H2BO HIST2H2BE HIST1H4A HIST1H4D HIST1H4F HIST1H4K HIST1H4J HIST1H4C HIST1H4H HIST1H4B HIST1H4E HIST1H4L HIST2H4A HIST1H2BK RUVBL1 HIST1H2BJ +REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION AKT3 RASGRP1 RASGRP2 ABCC4 RAPGEF3 VAV3 CAP1 GNA13 GNB5 CFL1 RAPGEF4 MGLL CLU COL1A1 COL1A2 LOC128192 LOC131691 DGKK CRK MAPK14 CSK PIK3R6 ADRA2A ADRA2B DGKA DGKB DGKG DGKH DGKQ CFD EGF A2M AKT1 AKT2 ALB F2 F2R F2RL2 F5 F8 F13A1 FCER1G DAGLB FGA FGB ALDOA FGG FIGF MMRN1 HABP4 FN1 PIK3R5 FYN LAT BRPF3 GNA11 GNA12 GNA15 GNAI1 GNAI2 GNAI3 GNAQ GNB1 GNB2 GNB3 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNGT1 GNGT2 GP1BA GP1BB GP5 GP9 GRB2 SCG3 HGF HRG HSPA5 APOA1 PPIAP8 APP ITGA2B ITGB3 ITPR2 ITPR3 KNG1 RHOA RHOB RHOG LAMP2 LCK LCP2 LYN ARRB1 ARRB2 MPL P2RY1 SERPINE1 PDGFA PDGFB PDPK1 PECAM1 GNG13 PF4 PFN1 SERPINA1 PIK3CA PIK3CB PIK3CG PIK3R1 PIK3R2 PLA2G4A PLCG2 PLG PLEK SERPINF2 GNG2 APBB1IP PPBP PPIA SRGN PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCQ PRKCZ MAPK1 MAPK3 GNG12 PROS1 PSAP TRPC7 PTK2 PTPN1 RAC1 RAC2 RAF1 RAP1A RAP1B GNB4 SELP POTEM LOC643997 SHC1 P2RY12 LOC652612 PPIAP22 LOC654188 SOD1 SOS1 SPARC SRC STX4 STXBP3 SYK TBXA2R TF TGFB1 TGFB2 TGFB3 LEFTY2 THBS1 THPO TIMP1 TLN1 SERPING1 TMSB4X TRPC3 TRPC6 TUBA4A LOC727848 LOC730221 LOC730335 VAV1 VCL VEGFA VEGFB VEGFC VWF DAGLA YWHAZ CALM1 CALM2 CALM3 ACTN4 CALU PIK3R3 DGKE DGKD ACTN1 ACTN2 F2RL3 DGKI CD9 GNG8 CD36 BCAR1 GNA14 CD63 WDR1 CDC42 +REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND POLD3 DNA2 FEN1 PCNA POLD1 POLD2 POLD4 RPA1 RPA2 RPA3 +REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS MASP2 CRP MBL2 MASP1 LOC651536 C1QA C1QB C1QC C1S LOC731066 +REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A ANAPC10 UBE2C CDC26 ANAPC2 ANAPC4 MAD2L1 NEK2 ANAPC5 ANAPC7 ANAPC11 RPS27A ANAPC1 LOC647654 LOC649620 LOC650621 LOC651763 BUB1B RPS27AP11 CDC26P1 LOC730594 UBA52 UBE2D1 UBE2E1 CDC23 CDC16 BUB3 CDC20 CDC27 +REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT MASP2 CRP CFD MBL2 MASP1 CFB LOC651536 LOC653879 C1QA C1QB C1QC C1S C2 C3 C4A LOC731066 +REACTOME_EXTENSION_OF_TELOMERES http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_EXTENSION_OF_TELOMERES POLD3 RUVBL2 DKC1 DNA2 FEN1 POLA2 LIG1 PCNA POLA1 POLD1 POLD2 POLE POLE2 WRAP53 PRIM1 PRIM2 NHP2 POLD4 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 TERT RUVBL1 +REACTOME_G2_M_CHECKPOINTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G2_M_CHECKPOINTS CDK2 DBF4 CHEK1 CHEK2 ORC6 ORC3 HUS1 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 ATM ORC1 ORC2 ORC4 ORC5 ATR MCM10 RAD1 RAD9A RAD17 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 LOC645084 LOC648152 LOC651610 LOC651921 WEE1 CDC7 CDC45 ATRIP MCM8 CCNB1 CCNB2 CDK1 CDC6 CDC25A CDC25C +REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT CHEK1 CHEK2 ATM ATR LOC648152 LOC651610 LOC651921 WEE1 ATRIP CCNB1 CDK1 CDC25C +REACTOME_S_PHASE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_S_PHASE CDK2 CDK4 PSMD14 CDK7 CDKN1A CDKN1B POLD3 CKS1B PSMA8 DNA2 FEN1 PSME4 ORC6 ORC3 POLA2 LIG1 MAX MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MNAT1 MYC ORC1 ORC2 ORC4 ORC5 PCNA GINS2 POLA1 POLD1 POLD2 POLE POLE2 PRIM1 PRIM2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 POLD4 RB1 CCND1 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 RPS27A SKP1 SKP2 LOC652826 RPS27AP11 LOC729964 UBA52 WEE1 CDT1 CDC45 GINS4 MCM8 CUL1 CCNA2 CCNA1 CCNE1 CCNH CCNE2 PSMF1 GINS1 PSMD6 CDC6 CDC25A CDC25B +REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 CDK2 PSMD14 CDKN1A CDKN1B CKS1B PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 RPS27A SKP1 SKP2 LOC652826 RPS27AP11 LOC729964 UBA52 CUL1 CCNA2 CCNA1 CCNE1 CCNE2 PSMF1 PSMD6 +REACTOME_TRYPTOPHAN_CATABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_TRYPTOPHAN_CATABOLISM AFMID ACMSD IDO2 HAAO IDO1 AADAT CCBL2 TDO2 KMO CCBL1 KYNU +REACTOME_DNA_STRAND_ELONGATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DNA_STRAND_ELONGATION POLD3 DNA2 FEN1 POLA2 LIG1 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 PCNA GINS2 POLA1 POLD1 POLD2 PRIM1 PRIM2 POLD4 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 CDC45 GINS4 MCM8 GINS1 +REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY CCNO SMUG1 APEX1 LIG3 MPG MUTYH NTHL1 OGG1 POLB TDG XRCC1 MBD4 +REACTOME_FGFR_LIGAND_BINDING_AND_ACTIVATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FGFR_LIGAND_BINDING_AND_ACTIVATION KLB FGF1 FGF2 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGF10 FGFR1 FGFR3 FGFR2 FGFR4 FGF20 FGF22 FGF23 FGF18 FGF17 KL FGF19 +REACTOME_CHOLESTEROL_BIOSYNTHESIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_CHOLESTEROL_BIOSYNTHESIS PMVK EBP CYP51A1 DHCR7 DHCR24 FDFT1 FDPS HMGCR HMGCS1 IDI1 LBR LSS MVD MVK NSDHL HSD17B7 MSMO1 SC5DL LOC651621 SQLE TM7SF2 LOC730412 IDI2 GGPS1 +REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION PSIP1 LOC128192 LOC131691 HMGA1 PPIAP8 PPIA APOBEC3G LOC643997 LOC645870 PPIAP22 LOC654188 BANF1 +REACTOME_GAP_JUNCTION_TRAFFICKING http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GAP_JUNCTION_TRAFFICKING GJC1 GJB6 AP2M1 CLTA CLTB CLTC GJB4 DAB2 DNM1 DNM2 GJD4 GJA1 GJA3 GJA4 GJA5 GJA8 GJB1 GJB2 GJB3 GJB5 GJB7 MYO6 GJC2 GJD2 GJA9 CLTCL1 GJA10 +REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION FGF1 FGF2 FGF4 FGF5 FGF6 FGF8 FGF9 FGFR2 FGF20 FGF23 FGF18 FGF17 +REACTOME_METABOLISM_OF_PORPHYRINS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_METABOLISM_OF_PORPHYRINS CPOX ALAD ALAS1 ALAS2 FECH HMBS HMOX1 HMOX2 UGT1A1 PPOX BLVRA BLVRB UROD UROS +REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION FGF1 FGF2 FGF4 FGF6 FGF8 FGF9 FGFR4 FGF20 FGF23 FGF18 FGF17 FGF19 +REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G PSMD14 PSMA8 PSME4 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMB10 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD7 PSMD8 PSMD9 PSMD10 PSMD11 PSMD12 PSMD13 PSME1 PSME2 APOBEC3G RPS27A TCEB1P3 LOC652826 TCEB1 TCEB2 RPS27AP11 UBA52 CUL5 PSMF1 PSMD6 RBX1 +REACTOME_SIGNALING_BY_FGFR http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SIGNALING_BY_FGFR AKT3 SPRY2 CDKN1A CDKN1B ADCY1 ADCY2 FRS3 FRS2 ADCY3 ADCY5 ADCY6 ADCY7 ADCY8 CHUK ADCY9 THEM4 CREB1 KLB ADRBK1 ADCY4 AKT1 AKT2 FGF1 FGF2 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGF10 FGFR1 FGFR3 FGFR2 FGFR4 FOXO1 FOXO3 PHLPP1 MTOR RICTOR GAB1 FGF20 FGF22 GRB2 GSK3A NR4A1 HRAS ITPR2 ITPR3 KRAS MDM2 FOXO4 NRAS PDE1A PDE1B PDPK1 PIK3CA PIK3R1 PLCG1 IL17RD PPP2CA PPP2CB PPP2R1A PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCD PRKCE PRKCG MAPK1 MAPK3 MAP2K1 MAP2K2 BAD PTEN TRIB3 RAF1 RPS6KB2 RPS27A MLST8 SHC1 SOS1 SRC BRAF TSC2 RPS27AP11 LOC729120 LOC730418 UBA52 LOC731292 YWHAB MAPKAP1 CALM1 CALM2 FGF23 CALM3 CAMK4 CASP9 AKT1S1 MKNK1 CBL FGF18 FGF17 KL CDK1 FGF19 +REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE TREH AMY1A AMY1B AMY1C AMY2A AMY2B LCT SI LOC648749 LOC652899 LOC730924 MGAM +REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION FGF1 FGF2 FGF3 FGF4 FGF5 FGF6 FGF8 FGF9 FGF10 FGFR1 FGF20 FGF22 FGF23 FGF17 +REACTOME_GAP_JUNCTION_ASSEMBLY http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_GAP_JUNCTION_ASSEMBLY GJC1 GJB6 GJB4 GJD4 GJA1 GJA3 GJA4 GJA5 GJA8 GJB1 GJB2 GJB3 GJB5 GJB7 GJC2 GJD2 GJA9 GJA10 +REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI PIGN PIGW PIGP PIGA PIGC PIGF PIGH PIGG PIGX PIGV SEMA6D PIGO DPM2 PIGQ PIGM PIGL PIGB +REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION CDK7 EHMT2 ERCC2 ERCC3 ERCC6 POLR1A GTF2H1 GTF2H2 GTF2H3 GTF2H4 MNAT1 POLR1D POLR2H POLR2K RRN3 LOC652857 GTF2H2B UBTF POLR1B KAT2B TAF1C TAF1B TAF1A CCNH POLR1C +REACTOME_PYRIMIDINE_METABOLISM http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PYRIMIDINE_METABOLISM UPP2 DCK DCTD DHODH DPYD DPYS DUT TYMP NT5C NT5E NT5C3 UPB1 NT5M AGXT2 TK1 TK2 TYMS UCK2 UMPS UPP1 CAD UCK1 NT5C1A CDA +REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS BCL2L11 DYNLL2 E2F1 AKT1 BBC3 GZMB APAF1 XIAP LOC441488 NMT1 PMAIP1 CYCS PPP3R1 MAPK8 DIABLO BAD BAK1 BAX BCL2 BCL2L1 BID TFDP1 TP53 YWHAB CASP3 CASP7 CASP8 CASP9 DYNLL1 BMF +REACTOME_PI3K_CASCADE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_PI3K_CASCADE FRS2 THEM4 KLB DOK1 EIF4B EIF4E EIF4EBP1 EIF4G1 AKT2 FGF1 FGF2 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGF10 FGFR1 FGFR3 FGFR2 FGFR4 MTOR GAB1 FGF20 FGF22 GRB2 EEF2K PIK3R4 INS INSR IRS1 PDE3B PRKAG2 PDPK1 CAB39 PIK3C3 PIK3CA PIK3CB PIK3R1 PIK3R2 PRKAG3 TLR9 PPM1A STRADB PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 RPTOR TRIB3 RHEB RPS6 RPS6KB1 MLST8 LOC644462 STK11 TSC1 TSC2 LOC729120 LOC730244 FGF23 CAB39L IRS2 FGF18 FGF17 STRADA KL FGF19 +REACTOME_APOPTOTIC_EXECUTION_PHASE http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_APOPTOTIC_EXECUTION_PHASE DNM1L BCAP31 ADD1 CTNNB1 DFFA DFFB DSG1 DSG2 DSG3 DSP ACIN1 FNTA GAS2 DBNL GSN H1F0 HIST1H1C HIST1H1D HIST1H1E HIST1H1B HIST1H1A HMGB1 HMGB2 APC BIRC2 KPNA1 KPNB1 LMNA LMNB1 MAPT OCLN PAK2 MST4 PKP1 PLEC PRKCD PRKCQ PTK2 ROCK1 SATB1 LOC647859 LOC652460 BMX SPTAN1 TJP1 ROCK1P1 VIM CASP3 CASP6 CASP7 CASP8 STK24 TJP2 CDH1 +REACTOME_SHC_RELATED_EVENTS http://www.broadinstitute.org/gsea/msigdb/cards/REACTOME_SHC_RELATED_EVENTS SHC2 GRB2 HRAS INS INSR KRAS NRAS SHC3 MAPK1 MAPK3 MAP2K1 MAP2K2 RAF1 SHC1 SOS1 YWHAB CDK1