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+The biological annotations used in this notebook correspond to version 6.2 (v6.2) of MsigDB categories h (hallmarks), c2 (subcategory reactome) and c5
+Updates of these biological annotations can be accessed at "http://software.broadinstitute.org/gsea/msigdb/download_file.jsp?filePath=/resources/msigdb/"
+a registration and subsequent login is required in order to download the signature collection.
+The three signatures collections (reactome,hallmarks and GO) are organized into .gmt files reporting in each line a signature and as first element the signature name (for further details refer to the msigDB website).