--- a
+++ b/app.py
@@ -0,0 +1,104 @@
+#!/usr/bin/env python
+# -*- coding: UTF-8 -*-
+'''
+@Project ：Auto-BioinfoGPT 
+@File    ：app.py
+@Author  ：Juexiao Zhou
+@Contact : juexiao.zhou@gmail.com
+@Date    ：2023/5/2 10:51 
+'''
+
+from src.agent import Agent
+import yaml
+import argparse
+import time
+
+def main(init_data_list,
+         output_dir,
+         init_goal_description,
+         model_engine,
+         openai_api,
+         execute,
+         blacklist,
+         gui_mode,
+         cpu,
+         rag):
+    AIAgent = Agent(initial_data_list=init_data_list,
+                    output_dir=output_dir,
+                    initial_goal_description=init_goal_description,
+                    model_engine=model_engine,
+                    openai_api=openai_api,
+                    execute=execute,
+                    blacklist=blacklist,
+                    gui_mode=gui_mode,
+                    cpu=cpu,
+                    rag=rag)
+    AIAgent.run()
+
+if __name__ == '__main__':
+
+    parser = argparse.ArgumentParser(description="ABC", add_help=False)
+    parser.add_argument('--config',
+                        help='path/to/config.yaml',
+                        default='./examples/case1.1/config.yaml')
+    parser.add_argument('--openai',
+                        help='openai api',
+                        default='SET_YOUR_OPENAI_API')
+    parser.add_argument('--model',
+                        help='name of model engine, e.g. gpt-4, please refer to model zoo',
+                        default='gpt-4')
+    parser.add_argument('--execute',
+                        help='execute code or only write codes',
+                        default=False,
+                        type=bool)
+    parser.add_argument('--blacklist',
+                        help='list of softwares in blacklist, default: java,perl,annovar',
+                        default='java,perl,annovar,Cutadapt,STAR',
+                        type=str)
+    parser.add_argument('--gui_mode',
+                        default=False,
+                        type=bool)
+    parser.add_argument('--cpu',
+                        default=False,
+                        type=bool)
+    parser.add_argument('--rag',
+                        help='Use RAG or not',
+                        default=False,
+                        type=bool)
+    args = parser.parse_args()
+
+    print("""
+
+  /$$$$$$              /$$               /$$$$$$$   /$$$$$$ 
+ /$$__  $$            | $$              | $$__  $$ /$$__  $$
+| $$  \ $$ /$$   /$$ /$$$$$$    /$$$$$$ | $$  \ $$| $$  \ $$
+| $$$$$$$$| $$  | $$|_  $$_/   /$$__  $$| $$$$$$$ | $$$$$$$$
+| $$__  $$| $$  | $$  | $$    | $$  \ $$| $$__  $$| $$__  $$
+| $$  | $$| $$  | $$  | $$ /$$| $$  | $$| $$  \ $$| $$  | $$
+| $$  | $$|  $$$$$$/  |  $$$$/|  $$$$$$/| $$$$$$$/| $$  | $$
+|__/  |__/ \______/    \___/   \______/ |_______/ |__/  |__/
+                                                            
+           Automated Bioinformatics Analysis
+                  www.joshuachou.ink
+    """)
+
+    with open(args.config, 'r') as file:
+        configs = yaml.safe_load(file)
+    print(configs)
+    init_data_list = configs['data_list']
+    output_dir = configs['output_dir']
+    init_goal_description = configs['goal_description']
+    start_time = time.time()
+    main(init_data_list,
+         output_dir,
+         init_goal_description,
+         args.model,
+         args.openai,
+         args.execute,
+         args.blacklist,
+         args.gui_mode,
+         args.cpu,
+         args.rag)
+    end_time = time.time()
+    print(f'\033[31m[Total time cost: {end_time-start_time}]\033[0m')
+