<table><tbody><tr><td><table cellpadding="2" cellspacing="0" width="600"><tbody><tr bgcolor="#cccccc" valign="top"><td colspan="2"><table width="600"><tbody><tr><td><strong class="acc" id="GSE226321"><a href="/geo/query/acc.cgi?acc=GSE226321" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_recenter)">Series GSE226321</a></strong></td>

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<td align="right" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_gds)"><a href="/gds/?term=GSE226321[Accession]">Query DataSets for GSE226321</a></td>

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<tr valign="top"><td>Status</td>

<td>Public on Apr 01, 2025</td>

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<tr valign="top"><td nowrap="">Title</td>

<td style="text-align: justify">Multimodal integration of transcriptomics, proteomics and radiomics improves prediction of recurrence in patients with IDH-mutant Glioma</td>

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<tr valign="top"><td nowrap="">Organism</td>

<td><a href="/Taxonomy/Browser/wwwtax.cgi?mode=Info&amp;id=9606" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_organismus)">Homo sapiens</a></td>

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<tr valign="top"><td nowrap="">Experiment type</td>

<td>Expression profiling by high throughput sequencing<br></td>

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<tr valign="top"><td nowrap="">Summary</td>

<td style="text-align: justify">Isocitrate dehydrogenase mutant gliomas remain lethal brain cancers which impair quality of life in young adults. These tumors are molecularly and cellularly heterogeneous and have a wide range of survival prognoses. Consequently, the identification of pa<br>Here, we analyzed imaging, transcriptomic, and proteomic profiles using machine learning to 1) describe the biological characterization of subtypes of IDH-mutant gliomas categorized by PET and histology, 2) reinforce the integration of PET metrics in the<br></td>

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<tr valign="top"><td nowrap="">&nbsp;</td>

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<tr valign="top"><td nowrap="">Overall design</td>

<td style="text-align: justify">Patient samples were collected during tumor resection and snap-frozen. RNAs were isolated from 59 patients with IDH-mutant gliomas and subjected to RNA sequencing.<br></td>

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<tr valign="top"><td nowrap="">&nbsp;</td>

<td></td>

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<tr valign="top"><td>Contributor(s)</td>

<td><a href="/pubmed/?term=Bikfalvi A[Author]">Bikfalvi A</a>, <a href="/pubmed/?term=Chouleur T[Author]">Chouleur T</a>, <a href="/pubmed/?term=Etchegaray C[Author]">Etchegaray C</a>, <a href="/pubmed/?term=Villain L[Author]">Villain L</a>, <a href="/pubmed/?term=Lesur A[Author]">Lesur A</a>, <a href="/pubmed/?term=Ferté T[Author]">Ferté T</a>, <a href="/pubmed/?term=Rossi M[Author]">Rossi M</a>, <a href="/pubmed/?term=Andrique L[Author]">Andrique L</a>, <a href="/pubmed/?term=Simoncini C[Author]">Simoncini C</a>, <a href="/pubmed/?term=Giacobbi A[Author]">Giacobbi A</a>, <a href="/pubmed/?term=Gambaretti M[Author]">Gambaretti M</a>, <a href="/pubmed/?term=Lopci E[Author]">Lopci E</a>, <a href="/pubmed/?term=Fernades B[Author]">Fernades B</a>, <a href="/pubmed/?term=Dittmar Olivier G[Author]">Dittmar Olivier G</a>, <a href="/pubmed/?term=Bjerkvig R[Author]">Bjerkvig R</a>, <a href="/pubmed/?term=Hejblum B[Author]">Hejblum B</a>, <a href="/pubmed/?term=Thiébaut R[Author]">Thiébaut R</a>, <a href="/pubmed/?term=Saut O[Author]">Saut O</a>, <a href="/pubmed/?term=Bello L[Author]">Bello L</a></td>

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<tr valign="top"><td>Citation missing</td>

<td class="message" id="pmidCell">Has this study been published? Please <a href="/geo/submitter">login</a> to update or <a href="mailto:geo@ncbi.nlm.nih.gov?subject=Citation for GSE226321 [not logged in]&amp;body=Thank you very much for helping to keep GEO citation links up-to-date. Please enter the PubMed ID (PMID) or full citation for GSE226321 below, and we will update the record accordingly within the next day or two. The PubMed ID or citation is:

">notify GEO</a>.</td>

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<tr valign="top"><td colspan="2"><span id="geo2r"></span> <span id="rnaseq_counts"></span></td></tr>

<tr bgcolor="#eeeeee" valign="top"><td>Submission date</td>

<td>Feb 28, 2023</td>

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<tr bgcolor="#eeeeee" valign="top"><td>Last update date</td>

<td>Apr 01, 2025</td>

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<tr bgcolor="#eeeeee" valign="top"><td>Contact name</td>

<td>Andreas Bikfalvi</td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">E-mail(s)</td>

<td><a href="mailto:andreas.bikfalvi@u-bordeaux.fr">andreas.bikfalvi@u-bordeaux.fr</a><br></td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Organization name</td>

<td style="text-align: justify">University of Bordeaux<br></td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Lab</td>

<td style="text-align: justify">U1312 BRIC<br></td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Street address</td>

<td style="text-align: justify">Allée Geoffroy St-Hilaire<br></td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">City</td>

<td style="text-align: justify">Pessac</td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">ZIP/Postal code</td>

<td style="text-align: justify">33615</td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Country</td>

<td style="text-align: justify">France</td>

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<tr valign="top"><td nowrap="">&nbsp;</td>

<td></td>

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<tr valign="top"><td>Platforms (1)</td>

<td onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_recenter)"><table cellpadding="3" style="position:relative;top:-5px;left:-5px"><tbody><tr><td valign="top"><a href="/geo/query/acc.cgi?acc=GPL16791" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_recenter)">GPL16791</a></td>

<td valign="top">Illumina HiSeq 2500 (Homo sapiens)</td>

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