<table><tbody><tr><td><table cellpadding="2" cellspacing="0" width="600"><tbody><tr bgcolor="#cccccc" valign="top"><td colspan="2"><table width="600"><tbody><tr><td><strong class="acc" id="GSE197672"><a href="/geo/query/acc.cgi?acc=GSE197672" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_recenter)">Series GSE197672</a></strong></td>

<td></td>

<td align="right" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_gds)"><a href="/gds/?term=GSE197672[Accession]">Query DataSets for GSE197672</a></td>

</tr></tbody></table></td></tr>

<tr valign="top"><td>Status</td>

<td>Public on Mar 04, 2022</td>

</tr>

<tr valign="top"><td nowrap="">Title</td>

<td style="text-align: justify">Genome-Wide DNA Methylation Profiling of the Failing Human Heart with Mechanical Unloading Identifies LINC00881 as an Essential Regulator of Calcium Handling in the Cardiomyocyte</td>

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<tr valign="top"><td nowrap="">Organism</td>

<td><a href="/Taxonomy/Browser/wwwtax.cgi?mode=Info&amp;id=9606" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_organismus)">Homo sapiens</a></td>

</tr>

<tr valign="top"><td nowrap="">Experiment type</td>

<td>Expression profiling by high throughput sequencing<br>Methylation profiling by genome tiling array<br></td>

</tr>

<tr valign="top"><td nowrap="">Summary</td>

<td style="text-align: justify">This SuperSeries is composed of the SubSeries listed below.<br></td>

</tr>

<tr valign="top"><td nowrap="">&nbsp;</td>

<td></td>

</tr>

<tr valign="top"><td nowrap="">Overall design</td>

<td style="text-align: justify">Refer to individual Series<br></td>

</tr>

<tr valign="top"><td nowrap="">&nbsp;</td>

<td></td>

</tr>

<tr valign="top"><td nowrap="">Citation(s)</td>

<td><span class="pubmed_id" id="36656640"><!--?xml version="1.0" encoding="UTF-8"?-->

<div class="PubmedCitation"><ul><li><span class="authors">Liao X, Kennel PJ, Liu B, Nash TR et al. </span><span class="title">Effect of mechanical unloading on genome-wide DNA methylation profile of the failing human heart. </span><span class="source">JCI Insight</span> 2023 Feb 22;8(4). PMID:&nbsp;<a title="Link to PubMed record" href="https://www.ncbi.nlm.nih.gov/pubmed/36656640">36656640</a></li></ul></div>

</span></td>

</tr>

<tr valign="top"><td>NIH grant(s)</td>

<td id="grantCell"><table id="orig_grantstable">

  <thead>

    <tr>

      <th>Grant ID</th>

      <th>Grant title</th>

      <th>Affiliation</th>

      <th>Name</th>

    </tr>

  </thead>

  <tbody>

    <tr>

      <td>K08 HL146964</td>

      <td>Defining the Role of lnc-TECRL in Maladaptive Cardiac Remodeling</td>

      <td>Trustees of Columbia University in the City of New York</td>

      <td>Veli Kemal Topkara</td>

    </tr>

  </tbody>

</table>

</td>

</tr>

<tr valign="top"><td colspan="2"><span id="geo2r"><button class="button" id="geo2r_button"><span class="">Analyze with GEO2R</span></button></span> <span id="rnaseq_counts"></span></td></tr>

<tr bgcolor="#eeeeee" valign="top"><td>Submission date</td>

<td>Mar 01, 2022</td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td>Last update date</td>

<td>Jan 26, 2023</td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td>Contact name</td>

<td>Veli K Topkara</td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td nowrap="">E-mail(s)</td>

<td><a href="mailto:vt2113@cumc.columbia.edu">vt2113@cumc.columbia.edu</a><br></td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Organization name</td>

<td style="text-align: justify">Columbia University<br></td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Department</td>

<td style="text-align: justify">Cardiology<br></td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Lab</td>

<td style="text-align: justify">Topkara Lab<br></td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Street address</td>

<td style="text-align: justify">622W 168th St, PH10-203A<br></td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td nowrap="">City</td>

<td style="text-align: justify">New York</td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td nowrap="">State/province</td>

<td style="text-align: justify">NY</td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td nowrap="">ZIP/Postal code</td>

<td style="text-align: justify">10032</td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Country</td>

<td style="text-align: justify">USA</td>

</tr>

<tr valign="top"><td nowrap="">&nbsp;</td>

<td></td>

</tr>

</tbody></table>