--- a +++ b/README.md @@ -0,0 +1,21 @@ +## Time series of epileptic seizures in a 8yo male on a cannabidiol trial +### Creators +Barry, Dwight + +### Description +Time series of epileptic seizures in a 8yo male with idiopathic catastrophic epilepsy (probably of mitochondrial origin) in a cannabidiol (CBD) trial. + +The data are of observed seizures during each day by the patient's parents and caregivers and thus are not exact values for total daily seizure activity; the values in this dataset are best considered a lower bound. However, observation effort was essentially constant over the time series, so the data likely reflect overall trends even though precise daily seizure counts are not available. + +The time series includes a 21-day baseline period and a 36-day trial period. The CBD was administered via g-tube in an olive oil base. Dosage was approximately 7.5 mg/kg/day for two weeks, and approximately 8 mg/kg/day for three weeks. + +Each 1ml of oil contained 10.00mg of total CBD and 0.42mg of total THC, for a CBD:THC ratio of approximately 20:1 (analysis by HPLC). + +Data Dictionary + +Date: YYYY-MM-DD +* Tonic: tonic seizure count (http://www.epilepsy.com/learn/types-seizures/tonic-seizures) +* Tonic-Clonic: tonic-clonic (aka "grand mal") seizure count (http://www.epilepsy.com/learn/types-seizures/tonic-clonic-seizures) +* Spasms: myoclonic seizure count (http://www.epilepsy.com/learn/types-seizures/myoclonic-seizures) +* Total: total number of seizures (sum of above) +* Notes: notes by parents \ No newline at end of file