--- a +++ b/README.md @@ -0,0 +1,31 @@ +##About Dataset + +### Background: +There is limited research available on the factors that affect survival in patients with non-cirrhotic hepatocellular carcinoma (HCC-NCL). Our goal was to develop and validate a nomogram and a new risk stratification system to evaluate the overall survival (OS) in patients with HCC-NCL. + +### Data gathering: +Clinical informations on patients diagnosed with hepatocellular carcinoma between 2010 and 2019 were gathered using SEER*Stat 8.4.0.1, encompassing information from 17 different centers. + +### Data collation: + inclusion criteria: (1) Hepatocellular carcinoma (HCC) selected using ICD-O-3 histological codes (8170-3, 8171-3, 8172-3, 8173-3, 8174-3, 8175-3); (2) HCC patients without cirrhosis (Ishak 0-4; No to moderate fibrosis; METAVIR F0-F3; Batt-Ludwig 0-3). + +### Exclusion criteria: +*(1) Race information unknown +*(2) Marital information unknown +*(3) Age less than 19 years or more than 100 years +*(4) Non-first primary tumor +*(5) Not pathologically confirmed by microscopy +*(6) Histological grade unknown +*(7) SEER grade unknown +*(8) T, N, M stage unknown +*(9) Surgical information unknown +*(10) Tumor size unknown +*(11) Survival information unknown. + + +A total of 15 covariates were selected for analysis in this study, namely age, marital status, gender, race, AFP, radiotherapy, chemotherapy, systemic therapy, surgery, T stage, N stage, M stage, AJCC stage, tumor size and histologic grade. All patients were staged according to AJCC 8th edition. + +The patients were categorized into three groups based on the RX Summ–Surg Prim Site (1998+) field. These groups include: +1) absence of surgery (A000); +2) local destruction of tumor (A100-A170); +3) liver resection or liver transplantation (A200-A750). \ No newline at end of file