A combination of HLA-DP α and β chain polymorphisms paired with a SNP in the DPB1 3' UTR region, denoting expression levels, are associated with Atopic Dermatitis

Creators

Margolis, David J.
Duke, Jamie L.
Mitra, Nandita
Berna, Ronald A.
Hoffstad, Ole J.
Wasserman, Jenna R.
Dinou, Amalia
Damianos, Georgios
Kotsopoulou, Ioanna
Tairis, Nikolaos
Ferriola, Deborah A.
Mosbruger, Timothy L.
Hayeck, Tristan J.
Yan, Albert C.
Monos, Dimitri S.

Description

The publication "A combination of HLA-DP α and β chain polymorphisms paired with a SNP in the DPB1 3’ UTR region, denoting expression levels, are associated with Atopic Dermatitis" contains analysis from two different cohorts: Genetics in Atopic Dermatitis (GAD), which is the main dataset, and Pediatric Eczema Elective Registry (PEER), which is the replication cohort. Included herein are the HLA Class II genotypes for both the GAD and PEER cohorts at 2-field resolution, which forms the basis for the analysis included in the publication. (DOI: 10.3389/fgene.2023.1004138)