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| Status |
Public on Dec 01, 2017 |
| Title |
RNA-seq in neutrophils from patients with intracranial aneurysms |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
In this study, we explored transcriptional differences in human neutrophils from patients with intracranial aneurysms and a demographic and comorbidity paired population of controls
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| Overall design |
We compared differentially expressed genes among neutrophils from 11 blood samples from patients with intracranial aneurysms and 11 blood samples from paired controls. We used an independent, unpaired, corroboration cohort of 5 intracranial aneurysm patients and 5 control patients to confirm our findings.
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| Contributor(s) |
Tutino VM, Meng H, Sun Y, Jarvis JN, Jiang K |
| Citation(s) |
- Tutino VM, Poppenberg KE, Jiang K, Jarvis JN et al. Circulating neutrophil transcriptome may reveal intracranial aneurysm signature. PLoS One 2018;13(1):e0191407. PMID: 29342213
- Poppenberg KE, Jiang K, Tso MK, Snyder KV et al. Epigenetic landscapes suggest that genetic risk for intracranial aneurysm operates on the endothelium. BMC Med Genomics 2019 Oct 30;12(1):149. PMID: 31666072
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| Submission date |
Nov 03, 2017 |
| Last update date |
Nov 12, 2019 |
| Contact name |
Hui Meng |
| Organization name |
University at Buffalo
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| Street address |
875 Ellicott Street
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| City |
Buffalo |
| ZIP/Postal code |
14203 |
| Country |
USA |
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