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| Status |
Public on Oct 22, 2020 |
| Title |
Whole blood transcriptomes of patients receiving digital subtraction angiography |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Circulating whole blood transcriptomes can detect the presence of unruptured cerebral aneurysms. Pending additional testing in larger cohorts, this could serve as a foundation to develop a simple blood-based test to facilitate screening and early detection of cerebral aneurysms.
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| Overall design |
We subjected RNA from peripheral whole blood of 47 patients undergoing cerebral digital subtraction angiogrpahy to next-generation RNA sequencing.
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| Contributor(s) |
Poppenberg KE, Tutino VM |
| Citation(s) |
- Poppenberg KE, Li L, Waqas M, Paliwal N et al. Whole blood transcriptome biomarkers of unruptured intracranial aneurysm. PLoS One 2020;15(11):e0241838. PMID: 33156839
- Tutino VM, Lu Y, Ishii D, Poppenberg KE et al. Aberrant Whole Blood Gene Expression in the Lumen of Human Intracranial Aneurysms. Diagnostics (Basel) 2021 Aug 10;11(8). PMID: 34441376
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| Submission date |
Oct 19, 2020 |
| Last update date |
Aug 31, 2021 |
| Contact name |
Kerry E Poppenberg |
| Organization name |
University at Buffalo
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| Street address |
875 Ellicott St
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| City |
BUFFALO |
| State/province |
NY |
| ZIP/Postal code |
14203 |
| Country |
USA |
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| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
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