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+<h1>Abstract</h1>
+<p>This dataset was collected as part of a prospective observational study to evaluate the effects of type 2 diabetes mellitus (DM) on cerebral vasoregulation, perfusion and functional outcomes, measured by blood flow responses to hypocapnia and hypercapnia, Valsalva maneuver, head-up tilt, and sit-to-stand test...</p>
+
+<h1>Background</h1>
+<p>Diabetes mellitus (DM) alters the permeability of the blood-brain barrier, thus affecting regional metabolism and microcirculatory regulation...</p>
+
+<h1>Methods</h1>
+<p>The study was approved by Institutional Review Board of Beth Israel Deaconess Medical Center (BIDMC #2008P000286)...</p>
+
+<h2>Recruitment</h2>
+<p>A total of 120 participants were recruited for the study based on inclusion and exclusion criteria...</p>
+
+<h2>Screening (First Visit)</h2>
+<p>Subjects were asked to sign informed consent form...</p>
+
+<h2>Visit 2 (Baseline)</h2>
+<p>Day 1: Subjects were admitted to CRC (Clinical Research Center)...</p>
+<p>Day 2: Blood was collected for fasting glucose, A1c (hemoglobin A1c), C-peptide, lipids, hematocrit, WBC (white blood cells count)...</p>
+
+<h2>Follow-up visits (6, 12, 18 months)</h2>
+<p>Subjects visited biannually for a follow-up visits that included measurements of fasting glucose, A1C, renal panels, vital signs, anthropometric and body fat measures...</p>
+
+<h2>Visit 8 (Two-year follow-up)</h2>
+<p>Identical to Visit 2 (Baseline).</p>
+
+<h1>Data Description</h1>
+<p>The GE-79_Protocol.pdf in the main directory contains the description of the experimental protocol.</p>
+
+<h2>1. Files in Data_Description directory:</h2>
+<ul>
+  <li>GE-79_Files_and Channels.csv - signals and calibration list.</li>
+  <li>GE-79_Files_per_subject.csv - files available for each subject.</li>
+  <li>GE-79_Summary_Table-Demographics-MRI-Part1.csv - demographics and MRI data.</li>
+  <li>GE-79_Summary_Table-MRI-Part2.csv - MRI data part 2.</li>
+  <li>GE-79_Summary_Table-MRI-Part3.csv - MRI data part 3.</li>
+  <li>GE-79_Summary_Table-MRI-Part4.csv - MRI data part 4.</li>
+  <li>GE-79_Summary_Table-MRI-Part5-History.csv - medical and medication history.</li>
+  <li>GE-79_Summary_Table-Labs-BP-Ophthalmogic-Walk.csv - labs, blood pressure, eye testing, walking test.</li>
+  <li>GE-79_Summary_Table-Cognitive-Testing.csv - cognitive testing results.</li>
+  <li>GE-79_Data_Dictionary.csv - variables dictionary with examples.</li>
+</ul>
+
+<h2>2. Files in Data directory:</h2>
+<ul>
+  <li>ECG files from 24 hour monitoring.</li>
+  <li>Labview - cardiovascular, respiratory, and TCD recordings during maneuvers.</li>
+</ul>
+
+<h1>Usage Notes</h1>
+<p>Formats in which the files are provided: ECG files converted to WFDB format, Labview files converted to WFDB format.</p>
+
+<h1>Ethics</h1>
+<p>The study was approved by Institutional Review Board of Beth Israel Deaconess Medical Center (BIDMC #2008P000286)...</p>
+
+<h1>Acknowledgements</h1>
+<p>The work was supported by the National Institutes of Health (NIH-NIA1R01-AG0287601A2, NIH-NIDDK 5R21 DK084463), American Diabetes Association (Clinical 1-03-CR-23 and 1-06-CR-25)...</p>
+
+<h1>Conflicts of Interest</h1>
+<p>Authors report no conflict of interest.</p>
+
+<h1>References</h1>
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