TCGA Chemotherapy Response Dataset
Creators
- Dalibor Hrg1
- Balthasar Huber2
- Lukas A. Huber1
Contributors
Contact persons:
Dalibor Hrg
Balthasar Huber
Description
Dataset on chemotherapeutic drug responses in TCGA cancer patients, cross-referenced for a hit in the TCIA.at database, consisting of clinical (TCGA), cancer tissue gene-expression (TCGA), and tumor-immunome (TCIA) features.
The dataset includes 5 common chemotherapy agents:
- 3 CRC agents: FOLFOX, 5FU, Oxaliplatin
- 2 Lung agents: Carboplatin, Cisplatin
FOLFOX, as a combinational therapy or regimen, was compiled from the timings of monotherapies given to patients and is thus a novel dataset derived from TCGA data. FOLFOX is primarily a first-line treatment, while the other drugs are not necessarily first-line treatments.
Each drug dataset is available in its own CSV file.
Citation
Dalibor Hrg, Balthasar Huber, Lukas A. Huber. (2020). TCGA Chemotherapy Response Dataset. Zenodo. http://doi.org/10.5281/zenodo.3719291
The results here are in whole or in part based upon data generated by the TCGA Research Network: https://www.cancer.gov/tcga
License
CC BY-SA 4.0 International https://creativecommons.org/licenses/by-sa/4.0. Authors take no liability for any use of this data.
Contributions
D. Hrg and B. Huber: major and equal work effort — data understanding, data science, and dataset preparation (monotherapies and FOLFOX).
L. A. Huber: contributed to the dictionary of drug names and curation/cleaning of FOLFOX entries, and clinical validation.
Contact & Maintenance
Email: dalibor.hrg@gmail.com
Institutional: dalibor.hrg@i-med.ac.at