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SKCM_auc_fit_table.csv
| # | cancer | drug | gene | lm_result_aic | gam_result_aic | rlm_result_aic | lm_result_r2 | gam_result_r2 | rlm_result_mse | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 1 | SKCM | dabrafenib | ATF1 | -1053.35319682673 | -1053.35319673007 | -1053.12600670466 | 7.42592147827643e-05 | -0.00111896961702262 | 0.0879428351814537 |
| 2 | 2 | SKCM | dabrafenib | B2M | -760.792828413445 | -760.792828343463 | -759.862566090667 | 0.000661836315949978 | -0.000530691354400759 | 0.101603195962835 |
| 3 | 3 | SKCM | dabrafenib | BAP1 | -502.481447195138 | -502.481447149106 | -497.668315318095 | 9.81115641164188e-05 | -0.00109508877525499 | 0.155939937014284 |
| 4 | 4 | SKCM | dabrafenib | BRAF | -528.773532863514 | -584.526358875739 | -526.425117109988 | 0.0170774322565627 | 0.0837275216138875 | 0.139223299518348 |
| 5 | 5 | SKCM | dabrafenib | CDKN2A | 980.663441791434 | 970.137332702161 | 980.66391131026 | 0.000369450761017043 | 0.0147247497001154 | 0.643687047759557 |
| 6 | 6 | SKCM | dabrafenib | CUX1 | -135.477962144393 | -145.160405293525 | -135.004514250646 | 0.00333988764797675 | 0.0163818052520941 | 0.167225720310219 |
| 7 | 7 | SKCM | dabrafenib | ERBB4 | -1309.01871464713 | -1313.28546195496 | -1304.93180743158 | 0.00461045878946116 | 0.0102272240260578 | 0.0744604290387142 |
| 8 | 8 | SKCM | dabrafenib | FAT4 | -1031.97422115962 | -1031.97422109289 | -1031.84598894603 | 8.45304335082542e-05 | -0.00110868610621306 | 0.146726674613741 |
| 9 | 9 | SKCM | dabrafenib | GNA11 | -900.166624214633 | -904.154159896697 | -899.871250957349 | 0.00192087837476487 | 0.0115604677867491 | 0.131409501524042 |
| 10 | 10 | SKCM | dabrafenib | GNAQ | -636.879107780651 | -636.879107723241 | -635.870909746751 | 0.00277451611524475 | 0.00158450957750345 | 0.143133264647784 |
| 11 | 11 | SKCM | dabrafenib | GRIN2A | -857.289310049309 | -858.264597097568 | -856.579661068913 | 0.00592282586247839 | 0.00691694789367359 | 0.111279938977493 |
| 12 | 12 | SKCM | dabrafenib | IRS4 | -280.10138232118 | -280.101382274014 | -278.90635888379 | 4.8285263460915e-05 | -0.00114497453765461 | 0.234398179429962 |
| 13 | 13 | SKCM | dabrafenib | KIT | -235.790175771901 | -235.790175747649 | -231.991377577652 | 0.000111322857467597 | -0.00108186172990932 | 0.139215036271265 |
| 14 | 14 | SKCM | dabrafenib | MAP2K1 | -1008.29307962776 | -1008.77792748531 | -1004.04092982924 | 0.000893129599378608 | 0.00173069286788652 | 0.103854966594839 |
| 15 | 15 | SKCM | dabrafenib | MAP2K2 | -958.935662546429 | -959.278071702058 | -958.392183081705 | 0.00203377464948738 | 0.00561983766296703 | 0.129189523952284 |
| 16 | 16 | SKCM | dabrafenib | MITF | -298.836663592347 | -360.064941249769 | -292.798389716937 | 0.0374583220139719 | 0.106607247085971 | 0.16548002648915 |
| 17 | 17 | SKCM | dabrafenib | NFKBIE | -197.809023622356 | -197.809023581469 | -197.576846256544 | 0.000277524986997636 | -0.000915461064596945 | 0.109995850949471 |
| 18 | 18 | SKCM | dabrafenib | NRAS | 61.0365201934956 | 61.0365202091785 | 66.6151432701456 | 0.000533813019593381 | -0.000658867374977223 | 0.127277246479894 |
| 19 | 19 | SKCM | dabrafenib | PPP6C | -785.191411292692 | -785.191411247211 | -783.953273226032 | 0.00757845073213509 | 0.00639417844435708 | 0.138693254192357 |
| 20 | 20 | SKCM | dabrafenib | PREX2 | -385.574263775028 | -386.013359064961 | -384.292923391839 | 0.000635409788375805 | 0.00564559876393589 | 0.150023982008551 |
| 21 | 21 | SKCM | dabrafenib | PTPRT | -151.471187333851 | -155.567875905743 | -149.161062653955 | 1.26295770932232e-05 | 0.0055918863647888 | 0.20461516842487 |
| 22 | 22 | SKCM | dabrafenib | RAC1 | -118.763236455987 | -119.237869692971 | -116.24064987178 | 0.00191581207112307 | 0.00199028900822029 | 0.210024822033855 |
| 23 | 23 | SKCM | dabrafenib | SALL4 | -70.2530858419471 | -73.885036959263 | -65.741974760021 | 0.00306006775778913 | 0.00905948487780728 | 0.22350188702002 |
| 24 | 24 | SKCM | dabrafenib | SFRP4 | -256.000871165708 | -255.927603681972 | -255.02939908289 | 0.00422086151399227 | 0.00301899861011334 | 0.200934971654465 |
| 25 | 25 | SKCM | dabrafenib | STAG2 | -284.619126601587 | -284.619126572549 | -283.485225421742 | 0.000653555473382667 | -0.000538982044227643 | 0.239914722903413 |
| 26 | 26 | SKCM | dabrafenib | TERT | 179.55243642726 | 178.101353039748 | 187.391424467953 | 0.00141318542944374 | 0.00302192420012037 | 0.237149593382338 |
| 27 | 27 | SKCM | dabrafenib | TRRAP | 160.045569620702 | 153.801329725835 | 164.433972903499 | 0.000956848351990455 | 0.0103097809029482 | 0.176636851044488 |
| 28 | 28 | SKCM | vemurafenib | ATF1 | -991.363553781503 | -991.363553691426 | -990.912136560405 | 0.000291648453654901 | -0.00100331058390712 | 0.0907625982744226 |
| 29 | 29 | SKCM | vemurafenib | B2M | -724.263502034125 | -724.263501946458 | -723.794865118797 | 0.000119633016255464 | -0.00117554879307291 | 0.0988023376463391 |
| 30 | 30 | SKCM | vemurafenib | BAP1 | -457.591199153034 | -458.570575690208 | -453.547978958062 | 1.18666682395105e-05 | 0.00101341873901206 | 0.158230512714726 |
| 31 | 31 | SKCM | vemurafenib | BRAF | -524.601178299133 | -543.899269662929 | -522.850898166782 | 0.0164305355511572 | 0.0431527730587605 | 0.139124409550242 |
| 32 | 32 | SKCM | vemurafenib | CDKN2A | 889.020509415293 | 888.229613373032 | 889.021335004201 | 0.00171767659136549 | 0.0023007706214172 | 0.629088919119484 |
| 33 | 33 | SKCM | vemurafenib | CUX1 | -114.605801279184 | -118.156470491965 | -113.733165877976 | 0.00367238848591746 | 0.00838079451458584 | 0.170711095577755 |
| 34 | 34 | SKCM | vemurafenib | ERBB4 | -1186.77582332853 | -1188.16094600015 | -1181.27574441591 | 0.00351205172494047 | 0.0051686717508781 | 0.0755487067027966 |
| 35 | 35 | SKCM | vemurafenib | FAT4 | -952.151244777669 | -952.151244726546 | -952.093949267197 | 0.001264669981525 | -2.90286595616696e-05 | 0.143663480570184 |
| 36 | 36 | SKCM | vemurafenib | GNA11 | -854.170869696118 | -854.720296630667 | -853.614402402317 | 0.00157990112815157 | 0.00197093393994296 | 0.133493757418544 |
| 37 | 37 | SKCM | vemurafenib | GNAQ | -594.422071292402 | -594.422071260601 | -594.170527039249 | 0.000576605864564494 | -0.000717984023272944 | 0.140929253339216 |
| 38 | 38 | SKCM | vemurafenib | GRIN2A | -752.22781077856 | -752.634094042733 | -751.399377572777 | 0.00215846558147576 | 0.00215926277789802 | 0.116576631205222 |
| 39 | 39 | SKCM | vemurafenib | IRS4 | -270.724183058526 | -270.724183033972 | -269.64442005539 | 0.00197663142593085 | 0.000683855027135749 | 0.230323377981396 |
| 40 | 40 | SKCM | vemurafenib | KIT | -196.708042400472 | -196.708042354062 | -192.88329482556 | 0.000905519636936014 | -0.000388644222433676 | 0.137282139930615 |
| 41 | 41 | SKCM | vemurafenib | MAP2K1 | -951.898509491037 | -951.96119257143 | -948.920858629202 | 1.44980752775227e-06 | -0.000869222164011862 | 0.101554507882713 |
| 42 | 42 | SKCM | vemurafenib | MAP2K2 | -886.509102057688 | -886.968758773682 | -885.856832602136 | 0.00264363784268381 | 0.00281568444290148 | 0.132186572347088 |
| 43 | 43 | SKCM | vemurafenib | MITF | -231.061434239393 | -291.586495291503 | -226.128238891722 | 0.0171988435228412 | 0.0962320256598029 | 0.170052117116167 |
| 44 | 44 | SKCM | vemurafenib | NFKBIE | -206.811401777164 | -206.811401754862 | -204.925652493983 | 0.00380685056627857 | 0.00251644495076986 | 0.112344907089393 |
| 45 | 45 | SKCM | vemurafenib | NRAS | 189.939678919554 | 189.939678937614 | 194.667187905552 | 0.00039077863165049 | -0.00090405193915255 | 0.126617148519746 |
| 46 | 46 | SKCM | vemurafenib | PPP6C | -704.930041146174 | -705.896195808181 | -704.393861547507 | 7.38663099069026e-07 | 0.00293006399393436 | 0.138226181811129 |
| 47 | 47 | SKCM | vemurafenib | PREX2 | -344.573161952319 | -344.573161914995 | -344.210046532238 | 1.95052277205043e-05 | -0.00127580631510837 | 0.150848554636757 |
| 48 | 48 | SKCM | vemurafenib | PTPRT | -95.53984254555 | -95.5467332335649 | -93.7172505191604 | 0.00419838656963684 | 0.00304069380022143 | 0.209944535219091 |
| 49 | 49 | SKCM | vemurafenib | RAC1 | -40.1167469942439 | -40.8316397917862 | -37.187246750988 | 0.000156216937220592 | 0.000998775326418788 | 0.215586955134902 |
| 50 | 50 | SKCM | vemurafenib | SALL4 | 4.94108245636159 | 4.94108248057409 | 9.83149676655271 | 0.00151263350775902 | 0.000219256075674301 | 0.23197033072912 |
| 51 | 51 | SKCM | vemurafenib | SFRP4 | -196.602156140085 | -196.688125770912 | -195.872212659277 | 1.14804699857439e-05 | -0.000719426837510362 | 0.198450307614833 |
| 52 | 52 | SKCM | vemurafenib | STAG2 | -272.362230317981 | -272.362230282523 | -271.437768527232 | 0.00248634854674612 | 0.00119423239701355 | 0.23523585961828 |
| 53 | 53 | SKCM | vemurafenib | TERT | 186.628495229291 | 185.636764397691 | 193.062824719079 | 0.000870757836601184 | 0.00186967431229368 | 0.246844224200701 |
| 54 | 54 | SKCM | vemurafenib | TRRAP | 26.7292794435499 | 26.1730228890497 | 30.1448596618958 | 0.00423360417284114 | 0.00438570122568871 | 0.178455949836454 |
| 55 | 55 | SKCM | dacarbazine | ATF1 | -927.600478836874 | -927.814437029373 | -927.346534500113 | 0.000351234995377386 | -0.00011394166165779 | 0.0924549070863056 |
| 56 | 56 | SKCM | dacarbazine | B2M | -677.440419850244 | -677.51969442951 | -676.8107472132 | 0.00114906544170668 | 0.000299115450178911 | 0.103149446491544 |
| 57 | 57 | SKCM | dacarbazine | BAP1 | -394.105808642513 | -394.105808603566 | -387.799759040301 | 0.00188831205096136 | 0.000521035739984965 | 0.151923288288773 |
| 58 | 58 | SKCM | dacarbazine | BRAF | -458.663559651648 | -458.663559591049 | -457.553352548471 | 0.00426683180376863 | 0.00290281373568801 | 0.132376625042566 |
| 59 | 59 | SKCM | dacarbazine | CDKN2A | 844.107214800125 | 844.107214805694 | 844.10746330937 | 0.00480013946744901 | 0.00343685198406884 | 0.614780881413227 |
| 60 | 60 | SKCM | dacarbazine | CUX1 | -84.5348067848301 | -84.5348067615982 | -84.1624087844909 | 0.00370638724235486 | 0.00234160147414719 | 0.169273075589378 |
| 61 | 61 | SKCM | dacarbazine | ERBB4 | -1143.14287268662 | -1143.1428725446 | -1140.33629776193 | 8.17443381098312e-05 | -0.00128800676970076 | 0.0745934443546546 |
| 62 | 62 | SKCM | dacarbazine | FAT4 | -911.413113289323 | -911.41311323041 | -911.38909924409 | 2.44373104973496e-05 | -0.00134539225438179 | 0.145055240907055 |
| 63 | 63 | SKCM | dacarbazine | GNA11 | -807.429207970409 | -807.429207902393 | -807.328786674025 | 1.49997728598002e-07 | -0.00136971274585362 | 0.130962225859894 |
| 64 | 64 | SKCM | dacarbazine | GNAQ | -596.332180590326 | -591.249535026459 | -595.988264771644 | 0.000853994951709575 | 0.00149829028969473 | 0.138679391541995 |
| 65 | 65 | SKCM | dacarbazine | GRIN2A | -707.021392296719 | -707.021392235401 | -705.528747496233 | 0.000120582725166963 | -0.00124911504982506 | 0.114101756517589 |
| 66 | 66 | SKCM | dacarbazine | IRS4 | -263.421704321819 | -263.421704298351 | -262.720820660917 | 0.000978354395391698 | -0.000390168419800885 | 0.237075805010329 |
| 67 | 67 | SKCM | dacarbazine | KIT | -3.229723710058 | -3.22972368817336 | 4.46937482359642 | 0.00377383771825125 | 0.0024091443355162 | 0.144766383077389 |
| 68 | 68 | SKCM | dacarbazine | MAP2K1 | -849.215813976609 | -849.215813918171 | -846.003313571449 | 1.1907287093507e-05 | -0.00135793944602147 | 0.100725038885767 |
| 69 | 69 | SKCM | dacarbazine | MAP2K2 | -851.999104508743 | -852.269329827302 | -851.658664958769 | 5.3325948306729e-06 | -0.000436246236167559 | 0.128854811254711 |
| 70 | 70 | SKCM | dacarbazine | MITF | -214.939115205646 | -215.223359702022 | -212.668365983358 | 0.000407991102031506 | 9.72677424363466e-05 | 0.163090086524221 |
| 71 | 71 | SKCM | dacarbazine | NFKBIE | -244.436217616051 | -245.387629918928 | -243.590909536396 | 0.000251789754775991 | 0.00117204312531305 | 0.110431846142837 |
| 72 | 72 | SKCM | dacarbazine | NRAS | 254.772931997871 | 254.77293201575 | 261.627493887264 | 0.000192457223847003 | -0.00117714215493447 | 0.130546228719758 |
| 73 | 73 | SKCM | dacarbazine | PPP6C | -671.58727679856 | -672.131347607924 | -670.378878689681 | 0.000137329783853178 | 0.000360103662924827 | 0.138948949225051 |
| 74 | 74 | SKCM | dacarbazine | PREX2 | -306.420300612657 | -303.973132767604 | -305.955148793605 | 0.00160228069778172 | 0.00381317304034112 | 0.165258534378896 |
| 75 | 75 | SKCM | dacarbazine | PTPRT | -108.256919571787 | -108.256919532642 | -106.370653795138 | 0.00173233998855659 | 0.000364850042022025 | 0.214051388020756 |
| 76 | 76 | SKCM | dacarbazine | RAC1 | -82.6748004135615 | -82.6748003877628 | -80.9056871928575 | 5.67341513102521e-05 | -0.00131305113320734 | 0.213216531991149 |
| 77 | 77 | SKCM | dacarbazine | SALL4 | -39.861330435689 | -39.8613304061103 | -36.323192788199 | 0.000542386317688877 | -0.000826733718106931 | 0.224260906794612 |
| 78 | 78 | SKCM | dacarbazine | SFRP4 | -267.507023098192 | -267.507023069594 | -267.073371586113 | 0.00459528721361906 | 0.00323171910057929 | 0.195947973858088 |
| 79 | 79 | SKCM | dacarbazine | STAG2 | -259.434037217814 | -259.434037195809 | -258.839575656116 | 0.000937664408101806 | -0.000430914145876482 | 0.242901490168887 |
| 80 | 80 | SKCM | dacarbazine | TERT | 134.377783469368 | 134.145726423181 | 139.419610577783 | 0.00040092691574713 | -7.83489914497615e-05 | 0.243019897092093 |
| 81 | 81 | SKCM | dacarbazine | TRRAP | 164.683906834826 | 164.590377399692 | 168.266844111184 | 0.00309190009707573 | 0.0022382395414221 | 0.183553854927495 |
| 82 | 82 | SKCM | trametinib | ATF1 | -1145.14867459124 | -1145.14867449701 | -1144.9924848304 | 2.65211640981357e-05 | -0.00107355968643486 | 0.0899835944516342 |
| 83 | 83 | SKCM | trametinib | B2M | -868.754921075698 | -868.754921016574 | -867.439309868392 | 0.00408692432240187 | 0.0029913104105026 | 0.097995025591059 |
| 84 | 84 | SKCM | trametinib | BAP1 | -532.988500519024 | -536.124871086667 | -527.284776891192 | 0.000508927093080822 | 0.00657667695320485 | 0.15546530428592 |
| 85 | 85 | SKCM | trametinib | BRAF | -607.422412129142 | -638.92085416375 | -604.898956117772 | 0.00860663831115366 | 0.0439186841044648 | 0.133018448486906 |
| 86 | 86 | SKCM | trametinib | CDKN2A | 1045.36908679949 | 1045.36908680893 | 1045.36986571435 | 0.0046381251432257 | 0.00354311757536863 | 0.626958445996905 |
| 87 | 87 | SKCM | trametinib | CUX1 | -171.290738903151 | -170.891170968189 | -169.963982283715 | 0.00757141001296943 | 0.0102002207984297 | 0.162856301881087 |
| 88 | 88 | SKCM | trametinib | ERBB4 | -1430.67493922202 | -1434.99244420699 | -1426.12619191461 | 0.00209900652646962 | 0.00930238651830906 | 0.0736826357065352 |
| 89 | 89 | SKCM | trametinib | FAT4 | -1125.5572447673 | -1125.55724467804 | -1125.52393932221 | 0.00348097273231655 | 0.00238469216911175 | 0.145584666698659 |
| 90 | 90 | SKCM | trametinib | GNA11 | -982.74423712488 | -986.624299987287 | -982.323149356566 | 0.00167332501264669 | 0.00731170701578188 | 0.130961328263336 |
| 91 | 91 | SKCM | trametinib | GNAQ | -702.502659353841 | -699.469711674651 | -701.868071270316 | 0.000330728939038317 | 0.00387671437071568 | 0.137221436030476 |
| 92 | 92 | SKCM | trametinib | GRIN2A | -921.512215788881 | -921.512215721885 | -920.64993299846 | 0.00430745496292556 | 0.003212083602261 | 0.110346441558414 |
| 93 | 93 | SKCM | trametinib | IRS4 | -329.478869233147 | -331.384097006304 | -328.2934951449 | 0.00316425216499557 | 0.00607170195739104 | 0.236275579646536 |
| 94 | 94 | SKCM | trametinib | KIT | -85.7292680909121 | -85.7292680626565 | -80.1376803931811 | 0.000986210014998192 | -0.00011281493240145 | 0.140276051067636 |
| 95 | 95 | SKCM | trametinib | MAP2K1 | -1108.39082035127 | -1108.3908202136 | -1104.28811920294 | 0.00535746336257512 | 0.0042632471555013 | 0.0965537678981319 |
| 96 | 96 | SKCM | trametinib | MAP2K2 | -1043.35694546367 | -1045.59730441857 | -1042.35951712623 | 0.00454450068371613 | 0.00904414797615793 | 0.128013016257325 |
| 97 | 97 | SKCM | trametinib | MITF | -229.917537903847 | -262.504301305067 | -224.25530540498 | 0.0194053261860282 | 0.0563374062603654 | 0.16498979365136 |
| 98 | 98 | SKCM | trametinib | NFKBIE | -260.473148106873 | -260.473148083082 | -260.166933013274 | 0.00331034987715595 | 0.00221388161891767 | 0.114556086534353 |
| 99 | 99 | SKCM | trametinib | NRAS | 193.004282400832 | 187.304008679143 | 199.34448982546 | 0.00745650745311983 | 0.0167277730295922 | 0.12604332502083 |
| 100 | 100 | SKCM | trametinib | PPP6C | -832.085204864877 | -832.08769752851 | -829.569050872089 | 0.000707123983294816 | -0.000314158301403022 | 0.135127456937794 |