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NSCLC_ec50_fit_table.csv
| # | cancer | drug | gene | lm_result_aic | gam_result_aic | rlm_result_aic | lm_result_r2 | gam_result_r2 | rlm_result_mse | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 1 | NSCLC | erlotinib | AKT1 | -410.518840464385 | -414.975800746829 | -409.474529457006 | 0.000386988777062156 | 0.00626178437369806 | 0.142606732038658 |
| 2 | 2 | NSCLC | erlotinib | ALK | -348.202892948318 | -354.095233492394 | -325.338073680373 | 0.0305430069638178 | 0.0370597589282737 | 0.0684963611087266 |
| 3 | 3 | NSCLC | erlotinib | BAP1 | -488.284429982656 | -491.653743632377 | -483.111056749344 | 0.00125480708641739 | 0.012285085458169 | 0.161334495185531 |
| 4 | 4 | NSCLC | erlotinib | BRAF | -577.047771200663 | -577.047771145672 | -575.738963494628 | 0.00488224883040773 | 0.00376539386349761 | 0.138989101279417 |
| 5 | 5 | NSCLC | erlotinib | CCDC6 | -575.387042259072 | -573.539633390351 | -574.345697404032 | 0.00157540436405426 | 0.00593924332872664 | 0.115025133776515 |
| 6 | 6 | NSCLC | erlotinib | CD74 | -999.198963371412 | -1013.1846272138 | -997.509526064116 | 0.00170347128161685 | 0.0185704861453772 | 0.117568194189458 |
| 7 | 7 | NSCLC | erlotinib | DDR2 | -665.677394253906 | -664.603205977168 | -663.935036007945 | 0.00041426478546191 | 0.00527691069424352 | 0.147115879443884 |
| 8 | 8 | NSCLC | erlotinib | DROSHA | 93.9323193350298 | 91.9757691579312 | 101.695668359069 | 3.49776607495659e-05 | 0.00439031955641156 | 0.216916795931368 |
| 9 | 9 | NSCLC | erlotinib | EGFR | 1161.11311190831 | 1164.87596527727 | 1179.09217454246 | 0.00282653026688696 | 0.00384816489732154 | 0.208379059570368 |
| 10 | 10 | NSCLC | erlotinib | EML4 | -1164.27510239674 | -1164.27738125796 | -1159.64478560871 | 0.00243685006312741 | 0.00138722523142842 | 0.0696615759481255 |
| 11 | 11 | NSCLC | erlotinib | ERBB2 | 1527.0188499733 | 1526.618047657 | 1550.95765863308 | 1.86143479833057e-08 | -0.000112726330629753 | 0.10282322563225 |
| 12 | 12 | NSCLC | erlotinib | ERBB4 | -1393.32507263231 | -1401.30660839891 | -1388.74640957695 | 0.000590264191348032 | 0.0137166161086225 | 0.0726895066500972 |
| 13 | 13 | NSCLC | erlotinib | EZR | -779.555659907929 | -779.555659853284 | -779.254286600716 | 8.72942566588321e-07 | -0.00112146055000761 | 0.141397922326119 |
| 14 | 14 | NSCLC | erlotinib | FGFR2 | -694.283718554029 | -694.283718464553 | -694.209822525275 | 1.50605869085859e-05 | -0.00110725700917502 | 0.123086378650308 |
| 15 | 15 | NSCLC | erlotinib | HIP1 | -398.091635875389 | -399.8408616837 | -394.660388630938 | 0.000828506197580828 | 0.00250369345872659 | 0.14867917665148 |
| 16 | 16 | NSCLC | erlotinib | KDR | -444.721481091923 | -444.721481041952 | -440.506635662773 | 0.000106840353315361 | -0.00101537421719722 | 0.139137758269946 |
| 17 | 17 | NSCLC | erlotinib | KEAP1 | -566.552140854652 | -566.533583200232 | -564.095553575475 | 0.00105268287457581 | -2.29458399667593e-05 | 0.122277765462489 |
| 18 | 18 | NSCLC | erlotinib | KIF5B | -359.238122372175 | -360.432907730222 | -358.492457634218 | 0.00484500209623796 | 0.00722956329538316 | 0.146307073566496 |
| 19 | 19 | NSCLC | erlotinib | LRIG3 | -1058.70920469099 | -1056.66872541338 | -1057.8272567186 | 0.00354891280216587 | 0.00425169478256882 | 0.086501036094084 |
| 20 | 20 | NSCLC | erlotinib | MAP2K1 | -1072.17169729821 | -1072.17169723277 | -1068.63376950474 | 0.0006595616256043 | -0.000462032378855115 | 0.0985771152933745 |
| 21 | 21 | NSCLC | erlotinib | MAP2K2 | -1005.1980559786 | -1005.19805588487 | -1004.46301419628 | 9.82923746792847e-05 | -0.00102393180273652 | 0.130699102018291 |
| 22 | 22 | NSCLC | erlotinib | NFE2L2 | -1109.35282871584 | -1107.81633037094 | -1098.09428678387 | 0.00126087417442563 | 0.00616836668157938 | 0.0617595370629901 |
| 23 | 23 | NSCLC | erlotinib | NRG1 | -382.654760396977 | -382.654760373078 | -382.513463812698 | 0.000360642393492252 | -0.00076128730963565 | 0.188518939884828 |
| 24 | 24 | NSCLC | erlotinib | PIK3CB | -621.917452756555 | -624.284070846011 | -618.28574978042 | 5.72591238229277e-05 | 0.00267571157380364 | 0.13374736297526 |
| 25 | 25 | NSCLC | erlotinib | PTPN13 | -1060.97894825689 | -1060.97894820218 | -1060.84098361241 | 0.000366650480423571 | -0.000755272465010837 | 0.145620499250496 |
| 26 | 26 | NSCLC | erlotinib | RET | -683.577279450835 | -681.986651606549 | -682.965559212746 | 5.69484402743233e-05 | 0.00513079585510956 | 0.115317878826045 |
| 27 | 27 | NSCLC | erlotinib | ROS1 | -671.257492435284 | -671.257492395654 | -670.851756884393 | 2.32982447188447e-05 | -0.00109901007948987 | 0.122689755028969 |
| 28 | 28 | NSCLC | erlotinib | SDC4 | -314.096178215487 | -314.559287221672 | -312.725715947481 | 0.00282896612711076 | 0.00830755918699855 | 0.214025886677503 |
| 29 | 29 | NSCLC | erlotinib | SLC34A2 | -707.238847385132 | -707.238847312213 | -705.343245490947 | 0.000383336984262038 | -0.000738567279717328 | 0.140527885570476 |
| 30 | 30 | NSCLC | erlotinib | SMARCA4 | -627.440693491675 | -627.440495196415 | -627.244828667724 | 3.60445965480967e-05 | -0.00108602810044611 | 0.11926566394525 |
| 31 | 31 | NSCLC | erlotinib | SOX2 | -813.725307577313 | -813.764543621841 | -812.8180077098 | 0.000589385329226624 | -0.000208274059585678 | 0.13421116184229 |
| 32 | 32 | NSCLC | erlotinib | STK11 | -344.645615575632 | -344.650797215487 | -338.607994931043 | 9.82726996278932e-05 | -0.000894064068871714 | 0.135784119434843 |
| 33 | 33 | NSCLC | erlotinib | TFG | -779.056952287844 | -779.944152783199 | -778.953572014857 | 0.00033372078929926 | 0.00459504407286937 | 0.115674903929106 |
| 34 | 34 | NSCLC | erlotinib | TPM3 | -273.389583905934 | -273.392263879513 | -265.606579646379 | 0.000806866323324555 | -0.000246183910119546 | 0.165378895853748 |
| 35 | 35 | NSCLC | erlotinib | TPR | -448.293164901216 | -449.987455666285 | -447.643561691505 | 0.00745016383207344 | 0.010444550746991 | 0.142875523583281 |
| 36 | 36 | NSCLC | docetaxel | AKT1 | -331.427446635448 | -331.42744660064 | -329.645598185684 | 0.00341606955307305 | 0.00232212453567138 | 0.141309925755498 |
| 37 | 37 | NSCLC | docetaxel | ALK | -344.816307276359 | -344.816307252 | -337.408211615495 | 0.00105767722066479 | -3.88565378148797e-05 | 0.0679891419258728 |
| 38 | 38 | NSCLC | docetaxel | BAP1 | -510.760944848519 | -510.760944808633 | -504.948647995077 | 0.000295365561660291 | -0.000802005039840292 | 0.157492595956208 |
| 39 | 39 | NSCLC | docetaxel | BRAF | -578.754889122681 | -579.48134757987 | -577.164389450121 | 2.32928686768215e-05 | 0.00770671267668532 | 0.135610732913449 |
| 40 | 40 | NSCLC | docetaxel | CCDC6 | -591.12196484888 | -591.121964779795 | -590.242447657471 | 0.000901777454595752 | -0.000194927523452293 | 0.114739185242146 |
| 41 | 41 | NSCLC | docetaxel | CD74 | -1039.21786537624 | -1039.21748390369 | -1037.65651771825 | 0.000837744994613148 | -0.000258936008830979 | 0.118305699231982 |
| 42 | 42 | NSCLC | docetaxel | DDR2 | -690.40243159586 | -690.975792079072 | -688.227755332567 | 7.39363202935857e-05 | 0.000173754555786054 | 0.143955027115479 |
| 43 | 43 | NSCLC | docetaxel | DROSHA | 92.985093035161 | 92.9850930605046 | 101.330267976039 | 0.00798720103560986 | 0.00689827369838791 | 0.21209696964781 |
| 44 | 44 | NSCLC | docetaxel | EGFR | 1175.69121956843 | 1175.69121958009 | 1193.29399075692 | 0.00101284248874982 | -8.37405465097252e-05 | 0.212478719682657 |
| 45 | 45 | NSCLC | docetaxel | EML4 | -1195.9562819083 | -1195.95628184464 | -1192.2588201952 | 0.00324239167109971 | 0.00214825595631729 | 0.0723485913097675 |
| 46 | 46 | NSCLC | docetaxel | ERBB2 | 1492.43705059197 | 1492.43705059888 | 1523.78831185298 | 0.0104145666395974 | 0.00932830381138727 | 0.10674489071926 |
| 47 | 47 | NSCLC | docetaxel | ERBB4 | -1425.01954796912 | -1419.72723953043 | -1420.4616354289 | 0.0015321048196245 | 0.00097991904726169 | 0.0721867426710548 |
| 48 | 48 | NSCLC | docetaxel | EZR | -803.599920572119 | -803.599698638635 | -803.204001844372 | 2.54659435113829e-05 | -0.00107185557537459 | 0.141246599549704 |
| 49 | 49 | NSCLC | docetaxel | FGFR2 | -716.458537668296 | -716.458537616627 | -716.371515252928 | 0.000815795744832119 | -0.000281003483185716 | 0.122559428241745 |
| 50 | 50 | NSCLC | docetaxel | HIP1 | -428.48440820155 | -428.484408136408 | -425.587395241278 | 0.000197472931990381 | -0.000900005177132845 | 0.152887766016912 |
| 51 | 51 | NSCLC | docetaxel | KDR | -465.271915504152 | -469.498781929023 | -460.672176315748 | 6.47044011396685e-06 | 0.00657636282870577 | 0.136874281583637 |
| 52 | 52 | NSCLC | docetaxel | KEAP1 | -609.302379112315 | -609.302379078777 | -608.153075963395 | 0.000130049827329508 | -0.000967502273459653 | 0.120909440156019 |
| 53 | 53 | NSCLC | docetaxel | KIF5B | -367.080797795833 | -367.080797745333 | -366.501295715962 | 7.07931221139573e-05 | -0.00102682403116638 | 0.1474991051235 |
| 54 | 54 | NSCLC | docetaxel | LRIG3 | -912.102995128694 | -912.102995060459 | -911.313784828239 | 5.9801407898412e-05 | -0.00103782782583561 | 0.089746705348626 |
| 55 | 55 | NSCLC | docetaxel | MAP2K1 | -1099.54835213941 | -1101.75199260559 | -1095.64611899351 | 0.00122578675993629 | 0.0057982783374072 | 0.100414809020953 |
| 56 | 56 | NSCLC | docetaxel | MAP2K2 | -1043.90114807172 | -1043.90114799649 | -1043.07877976045 | 0.000582483017538954 | -0.000514572474054287 | 0.127908195511098 |
| 57 | 57 | NSCLC | docetaxel | NFE2L2 | -1123.22873408953 | -1122.90876607399 | -1111.27258555324 | 0.000147087547941407 | -0.00108667466147838 | 0.0630320674358092 |
| 58 | 58 | NSCLC | docetaxel | NRG1 | -393.944670799471 | -393.944670747463 | -393.873692240373 | 0.00075765881924863 | -0.000339204369425916 | 0.186601488652753 |
| 59 | 59 | NSCLC | docetaxel | PIK3CB | -614.357671779877 | -614.357671713037 | -610.431634122897 | 1.53029403912238e-05 | -0.00108237513807508 | 0.140016499924121 |
| 60 | 60 | NSCLC | docetaxel | PTPN13 | -1102.94311005875 | -1107.19270897398 | -1102.7286261427 | 0.00481611352436871 | 0.0120824053983273 | 0.141928846560562 |
| 61 | 61 | NSCLC | docetaxel | RET | -671.900198984581 | -671.900198941145 | -671.053726249034 | 0.000191603241554674 | -0.000905880547254156 | 0.113014614478468 |
| 62 | 62 | NSCLC | docetaxel | ROS1 | -695.448985782583 | -695.683288502832 | -695.023375476079 | 0.000561939400387247 | 0.00239564826927663 | 0.122150093968483 |
| 63 | 63 | NSCLC | docetaxel | SDC4 | -324.046059056821 | -324.046059004482 | -322.818444491414 | 0.00131911730575186 | 0.000222870456807911 | 0.214043236906375 |
| 64 | 64 | NSCLC | docetaxel | SLC34A2 | -744.59806896151 | -744.163530513338 | -743.214318299135 | 0.000656724096752244 | 0.002152789833748 | 0.139453763027115 |
| 65 | 65 | NSCLC | docetaxel | SMARCA4 | -668.666926929555 | -668.666926859684 | -668.375737259883 | 3.81892276240098e-06 | -0.00109387168851405 | 0.115188188256352 |
| 66 | 66 | NSCLC | docetaxel | SOX2 | -848.104861497656 | -848.104861410008 | -847.093390670757 | 1.44606541532821e-05 | -0.00108321835674308 | 0.132073576213034 |
| 67 | 67 | NSCLC | docetaxel | STK11 | -365.11781954851 | -362.949046546104 | -358.261290953642 | 0.00308723563048207 | 0.00397293858468384 | 0.133152809113737 |
| 68 | 68 | NSCLC | docetaxel | TFG | -803.693118267966 | -802.935704471382 | -803.635016592844 | 0.000523420774272278 | 0.00206000239436854 | 0.117695365262327 |
| 69 | 69 | NSCLC | docetaxel | TPM3 | -324.991916907156 | -324.99191687052 | -316.413197880838 | 0.00234627157828085 | 0.00125115221024108 | 0.159301110947171 |
| 70 | 70 | NSCLC | docetaxel | TPR | -451.150470071927 | -451.15047004627 | -450.682133984766 | 5.2992027811265e-05 | -0.00104464465016485 | 0.142267835712047 |
| 71 | 71 | NSCLC | etoposide | AKT1 | -173.615616862106 | -173.615616833399 | -172.951094120318 | 0.00471466411646022 | 0.00256965258977959 | 0.141598314708254 |
| 72 | 72 | NSCLC | etoposide | ALK | -180.085035844354 | -180.085035832158 | -176.693138471039 | 1.37733471059285e-06 | -0.00215379210332745 | 0.066572474415803 |
| 73 | 73 | NSCLC | etoposide | BAP1 | -264.107240956017 | -264.223876673665 | -261.062277036953 | 0.0113346748209456 | 0.0101502069462525 | 0.155047532877524 |
| 74 | 74 | NSCLC | etoposide | BRAF | -303.25597964374 | -303.255979613513 | -302.512070921952 | 0.0147671607666025 | 0.0126438141885097 | 0.137934350741507 |
| 75 | 75 | NSCLC | etoposide | CCDC6 | -247.935964093927 | -247.938200535575 | -246.694533013708 | 0.00703758360767529 | 0.00501546451331325 | 0.116218603324968 |
| 76 | 76 | NSCLC | etoposide | CD74 | -520.965618444157 | -520.965618412501 | -520.151663420744 | 7.39949459200895e-05 | -0.00208101796704274 | 0.119525693812452 |
| 77 | 77 | NSCLC | etoposide | DDR2 | -357.381926886565 | -358.449062632883 | -356.494303237128 | 0.0130000575148453 | 0.0146599177949897 | 0.151551050039775 |
| 78 | 78 | NSCLC | etoposide | DROSHA | 45.6141398933211 | 35.1650825528488 | 50.1903217582874 | 0.00769281193341086 | 0.035321159344234 | 0.20647583875421 |
| 79 | 79 | NSCLC | etoposide | EGFR | 602.127175766011 | 601.82546117611 | 610.980958039228 | 4.50490278524977e-05 | 0.00276964053452577 | 0.210748450593597 |
| 80 | 80 | NSCLC | etoposide | EML4 | -606.734448307907 | -606.767745093208 | -604.538626789464 | 0.000294921850137056 | -0.00137311939520646 | 0.0713568176925426 |
| 81 | 81 | NSCLC | etoposide | ERBB2 | 823.953100722916 | 822.81809792771 | 838.492438396207 | 0.00246709398965678 | 0.00903087269370173 | 0.106113555607954 |
| 82 | 82 | NSCLC | etoposide | ERBB4 | -726.973824355211 | -726.546403599185 | -724.630737848931 | 0.0168976640427031 | 0.0192177754522517 | 0.0731657934118164 |
| 83 | 83 | NSCLC | etoposide | EZR | -417.951261207284 | -418.988827326438 | -417.703755054845 | 0.0131953530831706 | 0.0170459369326711 | 0.14165708497449 |
| 84 | 84 | NSCLC | etoposide | FGFR2 | -360.609632981982 | -360.609632949278 | -360.522555209444 | 0.000104153551225521 | -0.00205079442758738 | 0.123024543419653 |
| 85 | 85 | NSCLC | etoposide | HIP1 | -219.148054852885 | -219.14805483154 | -217.693565867165 | 0.00483119626956889 | 0.0026864360729667 | 0.150924852213921 |
| 86 | 86 | NSCLC | etoposide | KDR | -208.955908080477 | -204.115367636253 | -206.114575026756 | 0.000256608177589899 | -0.00258528835923677 | 0.135470265065082 |
| 87 | 87 | NSCLC | etoposide | KEAP1 | -308.820814289052 | -308.820814255336 | -308.095671256088 | 0.00130718085489983 | -0.000845174381805203 | 0.120182419084884 |
| 88 | 88 | NSCLC | etoposide | KIF5B | -177.855095479656 | -179.810932779145 | -177.520345002228 | 0.000123177409125536 | 0.0134190095508981 | 0.144729665087849 |
| 89 | 89 | NSCLC | etoposide | LRIG3 | -404.273702604247 | -404.273702580888 | -403.376308261945 | 0.000636006216090105 | -0.00151779550999409 | 0.089867386508005 |
| 90 | 90 | NSCLC | etoposide | MAP2K1 | -556.331397597201 | -556.331397547811 | -554.335716249186 | 0.00213190237074153 | -1.8675434895199e-05 | 0.102890991380916 |
| 91 | 91 | NSCLC | etoposide | MAP2K2 | -536.503653347356 | -536.503653290684 | -536.094758750444 | 0.00269416545854456 | 0.000544799440143073 | 0.127566478560679 |
| 92 | 92 | NSCLC | etoposide | NFE2L2 | -557.73493862417 | -561.332622172539 | -551.520801862105 | 6.81865545387289e-07 | 0.0116645728512267 | 0.0670766153120478 |
| 93 | 93 | NSCLC | etoposide | NRG1 | -192.904840824231 | -195.400602815595 | -192.872227487678 | 0.00359252158749095 | 0.00906733941133897 | 0.191630436940776 |
| 94 | 94 | NSCLC | etoposide | PIK3CB | -302.512611131265 | -302.707716317084 | -300.245133848088 | 0.00630222890131761 | 0.00538159310226605 | 0.135943118495072 |
| 95 | 95 | NSCLC | etoposide | PTPN13 | -547.296503203166 | -549.871029419572 | -547.254805848416 | 0.00255654145257916 | 0.00992448983394378 | 0.139828128681838 |
| 96 | 96 | NSCLC | etoposide | RET | -354.046059982724 | -355.251323072303 | -353.455971973396 | 0.00201122693940397 | 0.0126668920954099 | 0.1130665005504 |
| 97 | 97 | NSCLC | etoposide | ROS1 | -349.140891134485 | -349.140891115409 | -348.978214395359 | 0.000545722201736869 | -0.00160827409371289 | 0.123260430754105 |
| 98 | 98 | NSCLC | etoposide | SDC4 | -148.806691833243 | -163.551250604657 | -148.233055443805 | 0.000497810398047197 | 0.0343683532908278 | 0.21407354828527 |
| 99 | 99 | NSCLC | etoposide | SLC34A2 | -378.521018339038 | -380.89634017953 | -377.765129252436 | 0.00374455947687991 | 0.0103786475780084 | 0.140221442598147 |
| 100 | 100 | NSCLC | etoposide | SMARCA4 | -341.029576293955 | -336.166608318281 | -340.918580292695 | 0.000492014408591322 | -0.000593574787214335 | 0.115968061338794 |