Datasets:
Haley Delamora
Haley-Delamora/
Drug-Response-Driver-Gene
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[b8e226]: / CRC_ec50_mutaion_pvalues_summary.csv

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# gene drug p_t p_w p_m
1 1 AKT1 floxuridine 0.443210050301857 0.638822685776272 0.654991171889506
2 2 AKT1 regorafenib 0.46846068521181 0.978534260763616 0.866702629293892
3 3 AKT1 capecitabine 0.217785242997542 0.670524134711157 0.734360807867062
4 4 AKT1 carmofur 0.9190726897184 0.482687314265126 0.866541785106915
5 5 AKT1 5-fluorouracil 0.59401085011335 0.988780957311119 0.822704926624106
6 6 AKT1 SN-38 0.681451317781573 0.566149568981407 0.75933716680315
7 7 AKT1 ftorafur 0.089753904401837 0.159437747694614 0.101160290927879
8 8 AKT1 doxifluridine 0.0035567819551578 0.0315616851915496 0.0542441286802773
9 9 AKT1 tipiracil 0.802143246595278 0.915886933349763 0.361138996002114
10 10 AKT1 irinotecan 0.87535512840785 0.380427237515965 0.604763991238563
11 11 AKT1 oxaliplatin 0.743041759292516 0.626765755191241 0.814879679954617
12 12 APC floxuridine 0.570886701275651 0.384798866029678 0.134541409661773
13 13 APC regorafenib 0.59183142303608 0.421469225554554 0.502601863941477
14 14 APC capecitabine 0.525165437396528 0.214908371603926 0.113508730664508
15 15 APC carmofur 0.63612592803088 0.339165679833183 0.190770596633756
16 16 APC 5-fluorouracil 0.956262692949032 0.478245884123051 0.981489864271651
17 17 APC SN-38 0.550622646616661 0.344625918777116 0.152719849567705
18 18 APC ftorafur 0.540240174667141 0.353813774352628 0.341970472990288
19 19 APC doxifluridine 0.777414694028049 0.500958624995157 0.132806212350769
20 20 APC tipiracil 0.100519848609495 0.953859168352168 0.907119888694486
21 21 APC irinotecan 0.819995132456527 0.751925216574568 0.551186008492869
22 22 APC oxaliplatin 0.933062180211589 0.98906916853286 0.283465114969464
23 23 AXIN1 floxuridine 0.0495826673873149 0.0191420845893946 0.0131784797032019
24 24 AXIN1 regorafenib 0.723080482475935 0.521603052999971 0.207177632749514
25 25 AXIN1 capecitabine 0.984057493322657 0.570950784893937 0.254083385313525
26 26 AXIN1 carmofur 0.822837286778367 0.783147383274093 0.895830101629893
27 27 AXIN1 5-fluorouracil 0.954403581215752 0.911639615252287 0.841858585065851
28 28 AXIN1 SN-38 0.329613163029884 0.292390374666754 0.146092564491816
29 29 AXIN1 ftorafur 0.474822434991611 0.477914891723969 0.366354846900386
30 30 AXIN1 doxifluridine 0.101649579698897 0.880857906290601 0.336560634219214
31 31 AXIN1 tipiracil 0.841684854370998 0.328210780957709 0.476714365448448
32 32 AXIN1 irinotecan 0.891478478550352 0.726128983468664 0.428976239169412
33 33 AXIN1 oxaliplatin 0.425657014430874 0.159053796819644 0.154123252654812
34 34 AXIN2 floxuridine 0.0351350934311264 0.0650307829034761 0.109152723581378
35 35 AXIN2 regorafenib 0.955453211998341 0.749576142765459 0.775104531844261
36 36 AXIN2 capecitabine 0.41493820436095 0.578348282085845 0.658539581890766
37 37 AXIN2 carmofur 0.234781704706135 0.317524341041628 0.559887828683638
38 38 AXIN2 5-fluorouracil 0.874428497637507 0.903912860709628 0.821663985673951
39 39 AXIN2 SN-38 0.00151622818642026 0.0398517615022104 0.186737743515201
40 40 AXIN2 ftorafur 0.23205941792457 0.648815283710766 0.321432447696827
41 41 AXIN2 doxifluridine 0.484463867654928 0.191254528731492 0.0637950150792412
42 42 AXIN2 tipiracil 0.203607637070444 0.484406946188507 0.16565718729155
43 43 AXIN2 irinotecan 0.775265086439629 0.208021244304341 0.46211043166476
44 44 AXIN2 oxaliplatin 0.346247313681096 0.839856553711094 0.842849923726159
45 45 B2M floxuridine 0.0465329130495517 0.0304171312986591 0.0307162470922538
46 46 B2M regorafenib 0.575003236179957 0.509331472903172 0.328715481154318
47 47 B2M capecitabine 0.908842119552492 0.422560861556537 0.54668970932222
48 48 B2M carmofur 0.393865693741383 0.89099617793706 1
49 49 B2M 5-fluorouracil 0.821594904908506 0.714602870103525 0.784976179460165
50 50 B2M SN-38 0.30077734662775 0.387063673720324 1
51 51 B2M ftorafur 0.583643265203368 0.799290921400067 0.558824784423667
52 52 B2M doxifluridine 0.719322154866143 0.281497291733341 0.558518165605746
53 53 B2M tipiracil 0.393157386199451 0.585938540599359 1
54 54 B2M irinotecan 0.414790144367266 0.974710895696135 0.442342515993093
55 55 B2M oxaliplatin 0.0176474374357531 0.216592039943648 0.587545119241754
56 56 BAX floxuridine 0.472817593685325 0.41218102207932 0.245578336961661
57 57 BAX regorafenib 0.201148047117609 0.345522263700477 0.0979984341243588
58 58 BAX capecitabine 0.952259432852371 0.406112617937101 0.522381607502429
59 59 BAX carmofur 0.938782585826543 0.36376557256611 0.0308294735208177
60 60 BAX 5-fluorouracil 0.397415229712381 0.403211767972462 0.766226972773654
61 61 BAX SN-38 0.128280113465959 0.670504654473777 0.702780385191289
62 62 BAX ftorafur 0.167206460590709 0.331170023855943 0.0490626139319718
63 63 BAX doxifluridine 0.455074376531778 0.38008256856632 0.522610811780129
64 64 BAX tipiracil 0.586636858067355 0.244982793926483 0.778722932289204
65 65 BAX irinotecan 0.26096332990162 0.835587802024062 0.542746703989622
66 66 BAX oxaliplatin 0.588019137674967 0.45861292969539 0.159850061122251
67 67 BCL9L floxuridine 0.0480928638785004 0.094201255458447 0.100092351080712
68 68 BCL9L regorafenib 0.0644377755329166 0.0349428995265402 0.056133496344285
69 69 BCL9L capecitabine 0.12450092700224 0.0127914519783485 0.0215293265860341
70 70 BCL9L carmofur 0.944100224373968 0.994483474432304 0.503479944243963
71 71 BCL9L 5-fluorouracil 0.198089996136173 0.37939998752534 0.86214489497614
72 72 BCL9L SN-38 0.0510386269258142 0.174983219209287 0.345432242590099
73 73 BCL9L ftorafur 0.0230345170231871 0.107591193943523 0.0358839083672792
74 74 BCL9L doxifluridine 0.748897399851867 0.957717174621245 0.636505063723398
75 75 BCL9L tipiracil 0.772642730867199 0.41383671955164 0.656640574429275
76 76 BCL9L irinotecan 0.181240367967465 0.862605668948988 1
77 77 BCL9L oxaliplatin 0.126213601718765 0.794767959062616 0.555860090890362
78 78 BRAF floxuridine 0.545750897635211 0.615417768923061 0.982734764815379
79 79 BRAF regorafenib 0.0695318080938383 0.00295109667573397 0.0119681468073436
80 80 BRAF capecitabine 0.651624475380994 0.824079497111861 0.987189326551087
81 81 BRAF carmofur 0.144087204307861 0.203040668262747 0.520618477505272
82 82 BRAF 5-fluorouracil 0.152501814704826 0.170225192438951 0.38652348300832
83 83 BRAF SN-38 0.156154857664805 0.25342153772322 0.885556332844181
84 84 BRAF ftorafur 4.20067322864819e-05 0.000573891281513588 0.000188768224782335
85 85 BRAF doxifluridine 0.369545846846182 0.245496059175236 0.124950195530856
86 86 BRAF tipiracil 0.360377666722195 0.120326568954322 0.276592184031399
87 87 BRAF irinotecan 0.788299955979427 0.149940155969651 0.02495096936535
88 88 BRAF oxaliplatin 0.850344142199825 0.479125237438814 0.809108320432991
89 89 CTNNB1 floxuridine 0.00974441757604459 0.0289463636001442 0.0615036553611505
90 90 CTNNB1 regorafenib 0.608945095234036 0.792127442684963 0.392663557609933
91 91 CTNNB1 capecitabine 0.803766033483627 0.686882335317137 0.797265093950872
92 92 CTNNB1 carmofur 0.945234299255941 0.520385685462742 0.530017794379111
93 93 CTNNB1 5-fluorouracil 0.256189492625831 0.224667153738404 0.07209549506652
94 94 CTNNB1 SN-38 0.922151978585779 0.820484715203871 0.259746663091415
95 95 CTNNB1 ftorafur 0.40999752919558 0.955597137628278 0.863871649851779
96 96 CTNNB1 doxifluridine 0.0480536678918771 0.503519980000894 0.586931163916278
97 97 CTNNB1 tipiracil 0.737749599665407 0.0658843035735821 0.0597818940140813
98 98 CTNNB1 irinotecan 0.893472979975721 0.552241600969831 0.258621117801721
99 99 CTNNB1 oxaliplatin 0.960292351117882 0.215019159382397 0.0904262757346713
100 100 CUX1 floxuridine 0.14094146457802 0.173511698690878 0.331113013003851