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Haley Delamora
Haley-Delamora/
Drug-Response-Driver-Gene
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[b8e226]: / CML_auc_mutaion_pvalues_summary.csv

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# gene drug p_t p_w p_m
1 1 ABL1 bosutinib 0.560204106141388 0.539572356008582 0.190498204968988
2 2 ABL1 hydroxyurea 0.376698014827005 0.264710411761985 0.489315624258036
3 3 ABL1 busulfan 0.153072795919929 0.325462406097862 0.727220840682218
4 4 ABL1 dasatinib 0.0548762171562283 0.102004375259686 0.161013267987666
5 5 ABL1 decitabine 0.668484946108018 0.605671923625207 0.693857999051574
6 6 ABL1 cyclophosphamide 0.353054173535313 0.466797895287388 0.469237434025894
7 7 ABL1 homoharringtonine 0.0968210137585471 0.127074540646854 0.47832817223476
8 8 ABL1 ponatinib 0.115287359612154 0.144338475343726 0.12596853054699
9 9 ABL1 imatinib 0.909579730091668 0.82272289603293 0.796799496131214
10 10 ABL1 nilotinib 0.208695787524242 0.906131194559437 0.751832955886308
11 11 ABL1 mechlorethamine 0.711148045425048 0.536989195595097 0.364631283792775
12 12 BCR bosutinib 0.310351830406739 0.250647090512362 0.619951116327482
13 13 BCR hydroxyurea 0.317946856451598 0.783035680381392 0.649019005441833
14 14 BCR busulfan 0.00804227697341234 0.00423552998581153 0.0410836174394325
15 15 BCR dasatinib 0.138670930005506 0.156400971257029 0.30272626585253
16 16 BCR decitabine 0.614255190416532 0.611254811546201 0.24390866909346
17 17 BCR cyclophosphamide 0.574044878235413 0.608393715940753 0.854533346294668
18 18 BCR homoharringtonine 0.167660602046032 0.141421437893308 0.020825522471785
19 19 BCR ponatinib 0.437837318306834 0.742221147726187 0.745041875424536
20 20 BCR imatinib 0.0579557015004764 0.0624101923235168 0.13976567485433
21 21 BCR nilotinib 0.6961399053664 0.770598736679835 0.862699546592367
22 22 BCR mechlorethamine 0.479284455324293 0.61477188761348 0.872102592411129
23 23 CCDC6 bosutinib 0.996541197344456 0.904851783471976 0.994323274680269
24 24 CCDC6 hydroxyurea 0.00162040469524681 0.166854093026542 0.741670619038565
25 25 CCDC6 busulfan 0.105104872133984 0.0457396472739184 0.0184310085127179
26 26 CCDC6 dasatinib 0.523760756114392 0.511629306114578 0.152958081203137
27 27 CCDC6 decitabine 0.557066218097321 0.591596674855322 0.6336989795464
28 28 CCDC6 cyclophosphamide 0.328375411260226 0.546848081885587 0.652716680297733
29 29 CCDC6 homoharringtonine 0.0347583075550535 0.0812703991651943 0.0374337145478415
30 30 CCDC6 ponatinib 0.00480754792100018 0.0022572917194975 0.00668857674687773
31 31 CCDC6 imatinib 0.36643350601717 0.0985666031541565 0.222604580592386
32 32 CCDC6 nilotinib 0.860785048156441 0.39570551545834 0.20381646646009
33 33 CCDC6 mechlorethamine 0.429928321054158 0.638847739440584 0.736386840770004
34 34 CSF3R bosutinib 0.136985463207888 0.0720120266603806 0.0529368644099555
35 35 CSF3R hydroxyurea 0.31903104395749 0.490341550879811 0.991143131623763
36 36 CSF3R busulfan 0.164917013840597 0.149462811324851 0.263048459574764
37 37 CSF3R dasatinib 0.0769730350652108 0.0744342966611325 0.057442784091045
38 38 CSF3R decitabine 0.872730882018142 0.763579970376692 1
39 39 CSF3R cyclophosphamide 0.216903636347341 0.29437288682731 0.608683288585799
40 40 CSF3R homoharringtonine 0.281847754824569 0.0905638078017561 0.229082877829032
41 41 CSF3R ponatinib 0.14195159399811 0.18695975086302 0.560777014337938
42 42 CSF3R imatinib 0.685097405032864 0.493052887421188 0.538415433794335
43 43 CSF3R nilotinib 0.541692230596118 0.561835236179202 0.990979555197897
44 44 CSF3R mechlorethamine 0.740512888271736 0.390861082210118 0.359690269483792
45 45 ETNK1 bosutinib 0.845585315039712 0.711547088240551 0.994934100317087
46 46 ETNK1 hydroxyurea 0.921861544145531 0.454482546544841 0.994979184566768
47 47 ETNK1 busulfan 0.616682470204475 0.671212254954797 0.703344300061404
48 48 ETNK1 dasatinib 0.016178351482564 0.0519642832328756 0.0190802342871026
49 49 ETNK1 decitabine 0.791353276301269 0.909783388813761 0.779886225534015
50 50 ETNK1 cyclophosphamide 0.897602516767419 0.509758990839668 0.315066575369985
51 51 ETNK1 homoharringtonine 0.00788729738647783 0.0309057700443137 0.315374765554744
52 52 ETNK1 ponatinib 0.485485965972868 0.345774400968028 0.130377261766904
53 53 ETNK1 imatinib 0.837111009752342 0.569736410417976 0.783337533192978
54 54 ETNK1 nilotinib 0.799642876296044 0.786787676756813 0.472044717431676
55 55 ETNK1 mechlorethamine 0.019869641028803 0.0254696394005763 0.153731789325346
56 56 GATA2 bosutinib 0.00164020504271743 0.0271147742386064 0.00629728856334969
57 57 GATA2 hydroxyurea 0.0570105340463922 0.251715913923176 0.831432247184166
58 58 GATA2 busulfan 0.492540871159908 0.994233164926709 1
59 59 GATA2 dasatinib 0.555442447016756 0.520198099799488 0.506627837117
60 60 GATA2 decitabine 0.881349486143619 0.912384976839785 0.400200580917903
61 61 GATA2 cyclophosphamide 0.472085736699952 0.526735667453474 0.644878531842373
62 62 GATA2 homoharringtonine 0.677799962798149 0.997742586551495 0.522480334579688
63 63 GATA2 ponatinib 0.375485391526607 0.546119255935612 0.332117159473172
64 64 GATA2 imatinib 0.810928922067067 0.739871194518719 0.490891105274563
65 65 GATA2 nilotinib 0.760657832191225 0.658197356933587 0.509652181473928
66 66 GATA2 mechlorethamine 0.870982445400643 0.95448560542721 1
67 67 HOXA11 bosutinib 0.896882720464882 0.77860489255105 0.364230621354375
68 68 HOXA11 hydroxyurea 0.391160394064534 0.204012977636497 0.281757494621297
69 69 HOXA11 busulfan 0.484046979057004 0.399719582862615 0.103085753579562
70 70 HOXA11 dasatinib 0.510438468259326 0.514726631421719 1
71 71 HOXA11 decitabine 0.679819204840695 0.882100332859856 0.839065480338906
72 72 HOXA11 cyclophosphamide 0.97039455180067 0.897268614479504 0.735730044367604
73 73 HOXA11 homoharringtonine 0.663465653876287 0.645482217327568 0.696638045020648
74 74 HOXA11 ponatinib 0.0282065200749551 0.0601354119307408 0.124788678172025
75 75 HOXA11 imatinib 0.15559547853168 0.111443735050055 0.0667729141139182
76 76 HOXA11 nilotinib 0.743363389249687 0.808948197651685 0.993190852480386
77 77 HOXA11 mechlorethamine 0.361733284967925 0.502478590689742 0.760163340000881
78 78 JAK2 bosutinib 0.206334055919809 0.2769158574561 0.153397195179219
79 79 JAK2 hydroxyurea 0.368112727006809 0.710571826180177 0.695079509778147
80 80 JAK2 busulfan 0.783330047464332 0.734669939735035 1
81 81 JAK2 dasatinib 0.537941611002729 0.803596168969735 0.224966827481353
82 82 JAK2 decitabine 0.245688464080289 0.351788051521591 0.638296834844915
83 83 JAK2 cyclophosphamide 0.294948400462009 0.423101010376629 0.305878845571397
84 84 JAK2 homoharringtonine 0.102049687024295 0.0680612462532095 0.56612479984984
85 85 JAK2 ponatinib 0.679205683149319 0.5303149754037 0.574767012648384
86 86 JAK2 imatinib 0.267964009245157 0.560723004627914 0.873854422725451
87 87 JAK2 nilotinib 0.380274949008457 0.346117355395197 0.42618606466132
88 88 JAK2 mechlorethamine 0.932593933323309 0.770259115140838 0.674313678500488
89 89 MECOM bosutinib 0.870451053616379 0.743202413214818 0.566853100883867
90 90 MECOM hydroxyurea 0.307770911391599 0.6098866074308 0.338093863421908
91 91 MECOM busulfan 0.210869687669178 0.113514331138655 0.105441755660247
92 92 MECOM dasatinib 0.000347472844340733 0.000807371612344415 0.0359180496329916
93 93 MECOM decitabine 0.997101012427242 0.876085680007911 0.832145921182982
94 94 MECOM cyclophosphamide 0.265740923438415 0.138293778286159 0.156517929659501
95 95 MECOM homoharringtonine 0.692662254932791 0.777860930583789 0.833168357114798
96 96 MECOM ponatinib 0.113675808996159 0.17501388666286 0.69514547249948
97 97 MECOM imatinib 0.0868647691187171 0.0510572180789761 0.0692223387580551
98 98 MECOM nilotinib 0.627136542223886 0.503116760565339 0.555842041791346
99 99 MECOM mechlorethamine 0.60820281371629 0.851209933716735 0.659159860982597
100 100 MSI2 bosutinib 0.80828076686525 0.814159030089441 0.472111579914769