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Haley Delamora
Haley-Delamora/
Drug-Response-Driver-Gene
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[2c7117]: / CML_ec50_mutaion_pvalues_summary.csv

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# gene drug p_t p_w p_m
1 1 ABL1 bosutinib 0.0134419955017733 0.204195279626335 0.498617482959536
2 2 ABL1 hydroxyurea 0.64418145513848 0.30856885658864 0.507334157976344
3 3 ABL1 busulfan 0.517293237608445 0.379613122231537 1
4 4 ABL1 dasatinib 0.207057194621701 0.199223970312091 0.0976163058721906
5 5 ABL1 decitabine 0.894384508993574 0.549564839486275 0.237652510108176
6 6 ABL1 cyclophosphamide 0.462228576446389 0.604362665178944 1
7 7 ABL1 homoharringtonine 0.472011416446831 0.700793557826255 0.478328172234759
8 8 ABL1 ponatinib 0.81608261344809 0.252118475028118 0.195396073565302
9 9 ABL1 imatinib 0.18050571325478 0.132924277424679 0.136029937109026
10 10 ABL1 nilotinib 0.0174259148010122 0.0683148450268643 0.180473334526338
11 11 ABL1 mechlorethamine 0.80333962773076 0.901242720030214 0.856120242866631
12 12 BCR bosutinib 0.0664744276854344 0.0336774457695289 0.080675718660735
13 13 BCR hydroxyurea 0.874254898533028 0.454396412089638 0.626755611690376
14 14 BCR busulfan 0.00547588185501259 0.000914931362024518 0.00645785384505989
15 15 BCR dasatinib 0.886627574103327 0.888160393603618 0.422795154438437
16 16 BCR decitabine 0.914291246203858 0.681432844057321 0.815719071295726
17 17 BCR cyclophosphamide 0.255915181282208 0.23776618862513 0.0989355808370206
18 18 BCR homoharringtonine 0.358872887142606 0.229558884611463 0.151271243667842
19 19 BCR ponatinib 0.49459212373367 0.975810513227637 0.913682651879848
20 20 BCR imatinib 0.932433064483002 0.765610734590843 0.740170708070336
21 21 BCR nilotinib 0.557096809563834 0.530129195967665 0.264731018065097
22 22 BCR mechlorethamine 0.913361244728795 0.476830608118246 0.259777022425802
23 23 CCDC6 bosutinib 0.737915539084574 0.708856885506671 0.198816994554345
24 24 CCDC6 hydroxyurea 0.658674753519117 0.917041586963976 0.731594188531761
25 25 CCDC6 busulfan 0.00171909200040359 0.334920459415519 0.312458965333811
26 26 CCDC6 dasatinib 0.878344828311963 0.64879724029121 1
27 27 CCDC6 decitabine 0.778097723036071 0.889084610542487 1
28 28 CCDC6 cyclophosphamide 0.710036407253989 0.752313767272343 0.652716680297733
29 29 CCDC6 homoharringtonine 0.118257452142722 0.243058745326369 0.489960001005704
30 30 CCDC6 ponatinib 0.0282689384115115 0.0127662261711363 0.0238230899873225
31 31 CCDC6 imatinib 0.153950916073334 0.442318605741046 0.0873550614230544
32 32 CCDC6 nilotinib 0.387382944693773 0.277663751935183 0.52752613703769
33 33 CCDC6 mechlorethamine 0.0194942036042755 0.0922031644330465 0.312530840002515
34 34 CSF3R bosutinib 0.31708094345844 0.355132606037887 0.137314591571777
35 35 CSF3R hydroxyurea 0.159347290324261 0.405202614781857 0.408237264898748
36 36 CSF3R busulfan 0.89800119175915 0.792588431879519 0.263048459574764
37 37 CSF3R dasatinib 0.705654444809598 0.782619356188197 1
38 38 CSF3R decitabine 0.0670002018275029 0.0752037400892317 0.194587329985433
39 39 CSF3R cyclophosphamide 0.0325411397729879 0.234038848581267 0.305878845571397
40 40 CSF3R homoharringtonine 0.946859396026338 0.246593806220719 0.132231833889512
41 41 CSF3R ponatinib 0.714651857202977 0.264226842803237 0.771170722034952
42 42 CSF3R imatinib 0.432055709672478 0.987970572364803 0.367312329953061
43 43 CSF3R nilotinib 0.663855748236265 0.892907204791903 0.666789472227582
44 44 CSF3R mechlorethamine 0.00497223229739909 0.0718071754156216 0.169462436227213
45 45 ETNK1 bosutinib 0.344978754238023 0.379728205924766 0.479971000044447
46 46 ETNK1 hydroxyurea 0.392824134589822 0.97282910476878 0.994979184566768
47 47 ETNK1 busulfan 0.442676355970679 0.507427003219991 0.703344300061404
48 48 ETNK1 dasatinib 0.127674614942561 0.102147154340451 0.0682913137513439
49 49 ETNK1 decitabine 0.213735708338664 0.337261329641806 0.779886225534015
50 50 ETNK1 cyclophosphamide 0.922160813164637 0.726621574933536 1
51 51 ETNK1 homoharringtonine 0.0186249833077345 0.0236995576338026 0.0441626629408354
52 52 ETNK1 ponatinib 0.21819542740656 0.25896951052181 0.614117124471203
53 53 ETNK1 imatinib 0.785605570090119 0.251609467848843 0.163740311225492
54 54 ETNK1 nilotinib 0.915241618858276 0.365054566865707 0.472044717431676
55 55 ETNK1 mechlorethamine 0.316305102679522 0.924381852483028 0.475699353090271
56 56 GATA2 bosutinib 0.20020819455874 0.224826739225352 0.355382218691221
57 57 GATA2 hydroxyurea 0.490770060645379 0.563405936333486 0.831432247184166
58 58 GATA2 busulfan 0.136589819273414 0.422392863676419 0.335373569735401
59 59 GATA2 dasatinib 0.869034797372181 0.597730197159907 0.506627837117
60 60 GATA2 decitabine 0.170545027512342 0.35279411121781 0.613728934169523
61 61 GATA2 cyclophosphamide 0.200100065489572 0.172200443508636 0.0652481073771596
62 62 GATA2 homoharringtonine 0.791273286969681 0.785703560239478 0.335587854890197
63 63 GATA2 ponatinib 0.34805918540277 0.328815410306239 0.74647859577846
64 64 GATA2 imatinib 0.54973806430916 0.364477524068198 0.303200479033848
65 65 GATA2 nilotinib 0.52094929789199 0.380495182400221 0.115561763300595
66 66 GATA2 mechlorethamine 0.352032408294473 0.195866169555067 0.169462436227213
67 67 HOXA11 bosutinib 0.38277838527094 0.425822603901039 0.356385506554721
68 68 HOXA11 hydroxyurea 0.513029675518349 0.93966283146079 0.581797136988038
69 69 HOXA11 busulfan 0.119589087322413 0.0248006145167756 0.0297477690127786
70 70 HOXA11 dasatinib 0.523831241690196 0.988222265842278 0.690353997813568
71 71 HOXA11 decitabine 0.479858118569629 0.551969453649509 0.309893785165931
72 72 HOXA11 cyclophosphamide 0.691238997974221 0.746860873829387 0.311280086781461
73 73 HOXA11 homoharringtonine 0.461015849063196 0.895225726668093 0.439111496766299
74 74 HOXA11 ponatinib 0.394681913714636 0.0475764486210456 0.124788678172025
75 75 HOXA11 imatinib 0.62069434144393 0.967122389651655 0.538424267283501
76 76 HOXA11 nilotinib 0.409717246332565 0.536802345592386 0.274137238874049
77 77 HOXA11 mechlorethamine 0.835781532667583 0.456018738860953 0.760163340000881
78 78 JAK2 bosutinib 0.986412950215829 0.948781374395548 0.828185206247031
79 79 JAK2 hydroxyurea 0.105916763281523 0.181727434769961 0.695079509778147
80 80 JAK2 busulfan 0.135937436642635 0.0565494069087955 0.661411588333686
81 81 JAK2 dasatinib 0.977882488348501 0.868628303395423 1
82 82 JAK2 decitabine 0.374291614329561 0.486281984756526 0.87548616347244
83 83 JAK2 cyclophosphamide 0.807203597857287 0.852191467922976 0.608683288585799
84 84 JAK2 homoharringtonine 0.00549000001595568 0.0176143426471946 0.0424992417395414
85 85 JAK2 ponatinib 0.154643516726904 0.415947693098775 0.400030274668585
86 86 JAK2 imatinib 0.960284236181138 0.84366418288425 0.458012705005581
87 87 JAK2 nilotinib 0.226789132797058 0.547760261707596 0.412600555948003
88 88 JAK2 mechlorethamine 0.765393950356989 0.525630373256692 0.674313678500488
89 89 MECOM bosutinib 0.727796374625403 0.627858909393364 0.566853100883867
90 90 MECOM hydroxyurea 0.0655579700861732 0.0398464356403906 0.0671127691528874
91 91 MECOM busulfan 0.899242813712454 0.98892380952509 0.658813109473723
92 92 MECOM dasatinib 0.220449281167094 0.103381712109708 0.294211730882302
93 93 MECOM decitabine 0.87591495519688 0.553890878773383 0.524873891088126
94 94 MECOM cyclophosphamide 0.0706797594234846 0.0689992854621239 0.0833194060354228
95 95 MECOM homoharringtonine 0.809993640549611 0.893834176899031 0.833168357114798
96 96 MECOM ponatinib 0.531209210869652 0.769510304576788 0.69514547249948
97 97 MECOM imatinib 0.613729366177779 0.988507369069908 0.557377464269988
98 98 MECOM nilotinib 0.90251403494979 0.871539944192911 0.555842041791346
99 99 MECOM mechlorethamine 0.745573236226542 0.945527406320235 0.883112708971352
100 100 MSI2 bosutinib 0.726905015295676 0.837711290692118 0.479971000044447