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CML_auc_fit_table.csv
| # | cancer | drug | gene | lm_result_aic | gam_result_aic | rlm_result_aic | lm_result_r2 | gam_result_r2 | rlm_result_mse | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 1 | CML | bosutinib | ABL1 | -417.406659227627 | -438.839900526774 | -416.908324198545 | 0.00135172415236186 | 0.054757932578117 | 0.143506904326704 |
| 2 | 2 | CML | bosutinib | BCR | -164.119422639069 | -165.928433735 | -163.220153155686 | 0.000538173050993222 | 0.00927421586101129 | 0.135716278603279 |
| 3 | 3 | CML | bosutinib | CCDC6 | -234.093308508301 | -234.093308479885 | -233.087606008696 | 0.00110956390019454 | -0.00112509034520181 | 0.11827641631084 |
| 4 | 4 | CML | bosutinib | CSF3R | -479.584593724624 | -484.445420039421 | -479.267705830869 | 7.33988521027866e-05 | 0.0172708543602421 | 0.104610472773496 |
| 5 | 5 | CML | bosutinib | ETNK1 | 34.7803821793995 | 34.7803821965142 | 44.5132878638518 | 0.000553316136458425 | -0.00168258249428854 | 0.131947992039038 |
| 6 | 6 | CML | bosutinib | GATA2 | -394.814563332983 | -394.814563312748 | -393.440749009738 | 0.00540169270758032 | 0.00317664054815503 | 0.120709791526099 |
| 7 | 7 | CML | bosutinib | HOXA11 | -105.789834446513 | -105.789834428021 | -105.22963527099 | 0.00233558820787974 | 0.000103676752612247 | 0.200251382301267 |
| 8 | 8 | CML | bosutinib | JAK2 | 66.3889539521888 | 62.6327892844722 | 66.9269651211235 | 0.000264595622977946 | 0.0230009094998352 | 0.215732246183901 |
| 9 | 9 | CML | bosutinib | MECOM | -112.02087012944 | -109.078631569707 | -110.126769368552 | 0.00421468728085094 | 0.0100176414909452 | 0.169981977342855 |
| 10 | 10 | CML | bosutinib | MSI2 | -310.954713438095 | -310.954713397119 | -309.85732661447 | 0.00906829695832737 | 0.00685144748754019 | 0.130351381787404 |
| 11 | 11 | CML | bosutinib | PCM1 | -124.593465890817 | -124.593465874733 | -123.801843629764 | 0.0250423333043468 | 0.0228612199452963 | 0.195127197023742 |
| 12 | 12 | CML | bosutinib | PDGFRB | -481.132544620097 | -482.173993600146 | -479.865098316202 | 0.00324422039936533 | 0.00556702364765083 | 0.12133535426431 |
| 13 | 13 | CML | bosutinib | RPL22 | -491.220706867109 | -491.883754373909 | -490.491418701542 | 9.62540845677514e-05 | 0.00212476127035599 | 0.117752605975307 |
| 14 | 14 | CML | bosutinib | SETBP1 | -173.236642983171 | -173.236642956902 | -173.218296973625 | 4.10429548551752e-07 | -0.00223672513906159 | 0.202743741662525 |
| 15 | 15 | CML | hydroxyurea | ABL1 | -425.577883564515 | -430.595940652509 | -425.454067928771 | 0.00127153333084966 | 0.024916619279881 | 0.143457009056475 |
| 16 | 16 | CML | hydroxyurea | BCR | -196.193945026424 | -196.193945010666 | -195.343749181569 | 0.000769769349889703 | -0.00144581876048466 | 0.139443343435515 |
| 17 | 17 | CML | hydroxyurea | CCDC6 | -323.188213883424 | -323.188213867097 | -322.853132405431 | 0.000143786024969106 | -0.00207319007562057 | 0.116191886042943 |
| 18 | 18 | CML | hydroxyurea | CSF3R | -485.852712308357 | -484.858452564025 | -485.171329407004 | 0.000992301127834545 | 0.00903980846940455 | 0.106250656783157 |
| 19 | 19 | CML | hydroxyurea | ETNK1 | 51.8252486284441 | 51.8252486359146 | 60.0681968797197 | 0.000129208113123795 | -0.00208780030174482 | 0.139976122913952 |
| 20 | 20 | CML | hydroxyurea | GATA2 | -407.234041533072 | -407.234041507235 | -405.753590464678 | 0.00408138030418172 | 0.00187313502896413 | 0.121473439544167 |
| 21 | 21 | CML | hydroxyurea | HOXA11 | -164.557627367787 | -164.557627353505 | -164.186465819596 | 0.00314948822830391 | 0.000939176658473873 | 0.199063506779685 |
| 22 | 22 | CML | hydroxyurea | JAK2 | 51.1238652651043 | 50.6587294580482 | 51.8529433472685 | 0.00105725012919454 | 0.00193362392275498 | 0.216694733341839 |
| 23 | 23 | CML | hydroxyurea | MECOM | -119.484141633914 | -120.184244914745 | -116.733704560083 | 0.00371401521712521 | 0.00677776790734663 | 0.161647640309874 |
| 24 | 24 | CML | hydroxyurea | MSI2 | -320.14426069758 | -320.144260659686 | -318.554991997529 | 0.00354573358018161 | 0.00133630063710855 | 0.125657090388696 |
| 25 | 25 | CML | hydroxyurea | PCM1 | -113.85719725591 | -115.934478078714 | -113.461024326505 | 0.00153443595760091 | 0.00616400522998006 | 0.203557282240577 |
| 26 | 26 | CML | hydroxyurea | PDGFRB | -476.434894444625 | -476.434894417729 | -475.190613167838 | 0.000128129031460185 | -0.00208888178912536 | 0.120922503180466 |
| 27 | 27 | CML | hydroxyurea | RPL22 | -487.634830743439 | -487.634830698977 | -486.721260073381 | 0.000301629375013027 | -0.00191499677225648 | 0.118276307514642 |
| 28 | 28 | CML | hydroxyurea | SETBP1 | -189.48221665237 | -189.482216634745 | -189.468323069595 | 0.0126656583797828 | 0.0104764469844484 | 0.198260207371673 |
| 29 | 29 | CML | busulfan | ABL1 | -408.191905806583 | -408.237011057581 | -408.08854550987 | 7.27125810946981e-05 | -0.00166696747669048 | 0.13874378598651 |
| 30 | 30 | CML | busulfan | BCR | -114.319932482077 | -115.094788954389 | -113.155391363206 | 1.7868522814327e-05 | 0.0171418486630042 | 0.138967083845953 |
| 31 | 31 | CML | busulfan | CCDC6 | -262.559463566614 | -263.100489255989 | -261.844466433228 | 9.08218527261347e-05 | 0.00307082305330131 | 0.121112374714518 |
| 32 | 32 | CML | busulfan | CSF3R | -423.544048395338 | -423.544048366371 | -423.222054088359 | 0.00163964131598177 | -0.000843842195471511 | 0.115706852704414 |
| 33 | 33 | CML | busulfan | ETNK1 | 55.829143046253 | 55.8291430584116 | 63.8925023070175 | 0.00183223495133172 | -0.000650769449367372 | 0.132396519236686 |
| 34 | 34 | CML | busulfan | GATA2 | -346.572665077486 | -345.447147287607 | -345.130567678833 | 0.00504753025754629 | 0.00999105587240656 | 0.115979517805154 |
| 35 | 35 | CML | busulfan | HOXA11 | -86.4792880052623 | -86.4792879844762 | -85.9099299501385 | 0.00219522372120296 | -0.000286877628712601 | 0.202300781501645 |
| 36 | 36 | CML | busulfan | JAK2 | 60.2875555899392 | 60.1930998559256 | 60.7078873743234 | 0.000108210189707122 | -0.00145863121195999 | 0.222108159819071 |
| 37 | 37 | CML | busulfan | MECOM | -80.8299433933989 | -81.4097100520283 | -78.7721747447175 | 0.000116068669998539 | 0.000872943530065284 | 0.167192925864923 |
| 38 | 38 | CML | busulfan | MSI2 | -273.459059768456 | -273.459059745811 | -272.261359179195 | 0.000527591407994916 | -0.00195865838068476 | 0.129153452804942 |
| 39 | 39 | CML | busulfan | PCM1 | -168.681075925774 | -168.685970363261 | -168.648229450675 | 0.00791308779597045 | 0.00564701463334139 | 0.201690517252518 |
| 40 | 40 | CML | busulfan | PDGFRB | -453.445095067425 | -453.442648903382 | -452.151805932618 | 0.00318599838787811 | 0.00070382357644394 | 0.117391464923996 |
| 41 | 41 | CML | busulfan | RPL22 | -456.127098091861 | -456.127098070232 | -455.064413602348 | 0.00180430295688761 | -0.000678770937102335 | 0.119133489597357 |
| 42 | 42 | CML | busulfan | SETBP1 | -152.202990411693 | -152.202990398163 | -152.134493489621 | 1.13355720149826e-05 | -0.00247619843405222 | 0.209344154131438 |
| 43 | 43 | CML | dasatinib | ABL1 | -768.733133254769 | -768.733133213935 | -768.575826314775 | 0.000571771577487398 | -0.000653017809163714 | 0.141265452516869 |
| 44 | 44 | CML | dasatinib | BCR | -230.43776807746 | -230.437768055784 | -227.816629532149 | 0.00545689448556319 | 0.00423809171000344 | 0.137046722486657 |
| 45 | 45 | CML | dasatinib | CCDC6 | -602.907979125515 | -603.290834924151 | -602.276146988734 | 0.000534981469615405 | 0.00316676961660334 | 0.117421424044321 |
| 46 | 46 | CML | dasatinib | CSF3R | -881.739857021193 | -881.739856956371 | -881.500021486632 | 0.000719584845103324 | -0.000505023487560319 | 0.105851520487452 |
| 47 | 47 | CML | dasatinib | ETNK1 | 107.794887987327 | 107.794871300674 | 129.602721668296 | 0.00515168017374498 | 0.00393572694325672 | 0.129044490792153 |
| 48 | 48 | CML | dasatinib | GATA2 | -740.616279672611 | -740.616279584213 | -738.149443186096 | 0.000284619536633366 | -0.000940521906988678 | 0.120911686335328 |
| 49 | 49 | CML | dasatinib | HOXA11 | -149.327710494613 | -147.512237703699 | -148.324601782523 | 0.00241713560695527 | 0.00566177419799996 | 0.193963549132691 |
| 50 | 50 | CML | dasatinib | JAK2 | 103.234993951697 | 102.629849270543 | 104.796109490529 | 4.75929016253083e-05 | 0.00134720183025561 | 0.218766755251112 |
| 51 | 51 | CML | dasatinib | MECOM | -231.591437330873 | -231.591437284615 | -226.759028981632 | 0.00642419427957314 | 0.00520657685805492 | 0.164764813515953 |
| 52 | 52 | CML | dasatinib | MSI2 | -555.054707521631 | -556.106157183338 | -550.53413291804 | 0.000819263189326283 | 0.00177051197704459 | 0.124803501413336 |
| 53 | 53 | CML | dasatinib | PCM1 | -202.280601025152 | -203.540296286962 | -201.285255602469 | 0.0019857171482664 | 0.00485915225620148 | 0.198750030624555 |
| 54 | 54 | CML | dasatinib | PDGFRB | -873.946829573071 | -873.946829513432 | -871.769478940567 | 0.000194361524236503 | -0.00103089050381167 | 0.119705920502182 |
| 55 | 55 | CML | dasatinib | RPL22 | -876.228964457897 | -876.228964395687 | -874.870598350191 | 0.00129921921736352 | 7.53211658383046e-05 | 0.116776775533746 |
| 56 | 56 | CML | dasatinib | SETBP1 | -320.43445248133 | -325.028577387288 | -320.41482865574 | 3.73302802674527e-06 | 0.0110706567356641 | 0.205743778008203 |
| 57 | 57 | CML | decitabine | ABL1 | -753.679736962071 | -756.274268289818 | -753.370186413496 | 0.000170803297688172 | 0.00782365661352913 | 0.14303032704655 |
| 58 | 58 | CML | decitabine | BCR | -262.755399023825 | -262.755398982949 | -261.58077718094 | 0.00177509740131327 | 0.000517887219443125 | 0.136526355748799 |
| 59 | 59 | CML | decitabine | CCDC6 | -465.588048277819 | -461.370898396466 | -464.458860764018 | 0.00680122774139974 | 0.00913780134386566 | 0.118287645420252 |
| 60 | 60 | CML | decitabine | CSF3R | -869.867658772708 | -869.867658663741 | -869.610704993131 | 6.90415058197932e-05 | -0.00119031729057562 | 0.107844162405158 |
| 61 | 61 | CML | decitabine | ETNK1 | 77.8307247716137 | 79.138430341469 | 93.6584241993714 | 0.00150878083893592 | 0.00552997475970296 | 0.130060440102668 |
| 62 | 62 | CML | decitabine | GATA2 | -709.82276953031 | -709.822769444123 | -707.647828001468 | 0.00459822464694646 | 0.00334456997410171 | 0.119058635353706 |
| 63 | 63 | CML | decitabine | HOXA11 | -151.656894239935 | -151.671694778654 | -150.818137158536 | 0.000563599131948519 | -0.00049867566959616 | 0.196022710086166 |
| 64 | 64 | CML | decitabine | JAK2 | 86.6850889625807 | 84.0821380310572 | 87.3171754457129 | 0.000528837972816265 | 0.00403439195241151 | 0.219045802600584 |
| 65 | 65 | CML | decitabine | MECOM | -205.720762238964 | -204.705412046092 | -202.631499652206 | 0.000418718549772054 | 0.00620879113659834 | 0.167667606204982 |
| 66 | 66 | CML | decitabine | MSI2 | -527.870007547911 | -527.87000751787 | -524.941239086257 | 0.000309497966561448 | -0.000949558049248234 | 0.127741550366353 |
| 67 | 67 | CML | decitabine | PCM1 | -206.442216925583 | -206.442216895495 | -205.786494902369 | 0.00134608505253957 | 8.83345164723881e-05 | 0.195470262103839 |
| 68 | 68 | CML | decitabine | PDGFRB | -850.824581742542 | -850.824581656422 | -848.436982180317 | 0.000291251994259635 | -0.000967827068311999 | 0.119439046191715 |
| 69 | 69 | CML | decitabine | RPL22 | -849.583639410166 | -849.583639336204 | -847.988559773905 | 0.000652875251836971 | -0.000605748314480348 | 0.115904653715503 |
| 70 | 70 | CML | decitabine | SETBP1 | -301.159461896839 | -301.128226036395 | -301.086837088172 | 0.0041783441678073 | 0.0112518787833868 | 0.208851902788397 |
| 71 | 71 | CML | cyclophosphamide | ABL1 | -309.976044461223 | -311.386108160543 | -309.370066728855 | 0.000619490245970414 | 0.00740315893607513 | 0.144456189142723 |
| 72 | 72 | CML | cyclophosphamide | BCR | -95.0427867507432 | -95.0427867431542 | -94.373723641234 | 2.69743301055475e-05 | -0.00305936217840697 | 0.14482003583367 |
| 73 | 73 | CML | cyclophosphamide | CCDC6 | -268.980544320395 | -268.980544306112 | -268.860457152659 | 0.00340163675703533 | 0.000325715876639876 | 0.120956522738541 |
| 74 | 74 | CML | cyclophosphamide | CSF3R | -334.944239783542 | -331.49304325782 | -334.518626484198 | 4.71148376838329e-05 | 0.00588319715137864 | 0.111323121493863 |
| 75 | 75 | CML | cyclophosphamide | ETNK1 | 46.6781247925615 | 43.3537475108696 | 54.177876873207 | 0.000983375785217646 | 0.0303620093930053 | 0.145469257091535 |
| 76 | 76 | CML | cyclophosphamide | GATA2 | -263.537871102123 | -263.537871080481 | -262.373500003514 | 0.00402441391227352 | 0.000950415158687323 | 0.123108053064027 |
| 77 | 77 | CML | cyclophosphamide | HOXA11 | -115.347605813071 | -116.459026649331 | -115.15774392947 | 6.11060864346138e-05 | 0.0103813883131854 | 0.20070048880399 |
| 78 | 78 | CML | cyclophosphamide | JAK2 | 53.6638751822404 | 53.6638751882517 | 54.2387670079439 | 0.0109387987231377 | 0.00788614068933813 | 0.222608218253728 |
| 79 | 79 | CML | cyclophosphamide | MECOM | -69.0673388751811 | -69.5446940631153 | -67.7830787118418 | 0.00497321057783309 | 0.00842659023785619 | 0.16237309872371 |
| 80 | 80 | CML | cyclophosphamide | MSI2 | -199.46969271413 | -199.469692687198 | -197.656366006806 | 0.0079053942552594 | 0.00484337383672984 | 0.123288490893008 |
| 81 | 81 | CML | cyclophosphamide | PCM1 | -140.138987474845 | -140.138987459898 | -140.121188277863 | 0.000214217051527134 | -0.00287154154602565 | 0.201608572645175 |
| 82 | 82 | CML | cyclophosphamide | PDGFRB | -361.271790962685 | -361.271790938296 | -360.254981297482 | 0.000430291539389468 | -0.00265480017929032 | 0.123889606541916 |
| 83 | 83 | CML | cyclophosphamide | RPL22 | -367.320652143474 | -367.320652116796 | -366.4826432274 | 0.000843072733508 | -0.00224074498151894 | 0.119471068895973 |
| 84 | 84 | CML | cyclophosphamide | SETBP1 | -149.5571547518 | -150.338398865054 | -149.428511216474 | 0.00410934142402754 | 0.00535976948958194 | 0.208563011017817 |
| 85 | 85 | CML | homoharringtonine | ABL1 | -844.765228889719 | -844.76522879526 | -844.43689115184 | 0.000536612737295985 | -0.000587643062633925 | 0.1397085605069 |
| 86 | 86 | CML | homoharringtonine | BCR | -284.137871047162 | -284.116136114625 | -282.179734624429 | 0.000426801626690058 | 0.00469719806300806 | 0.138035125614782 |
| 87 | 87 | CML | homoharringtonine | CCDC6 | -582.45793050837 | -582.457930476565 | -581.484358507293 | 4.38163607818917e-06 | -0.00112047283459593 | 0.117148736015119 |
| 88 | 88 | CML | homoharringtonine | CSF3R | -966.631289249415 | -967.906358971877 | -966.363758942295 | 0.0099453709059399 | 0.0112407328791417 | 0.110273401685644 |
| 89 | 89 | CML | homoharringtonine | ETNK1 | 85.5744259945217 | 85.5744260313929 | 103.54594053386 | 2.3534612665294e-05 | -0.0011012983251586 | 0.131483991443994 |
| 90 | 90 | CML | homoharringtonine | GATA2 | -776.902039058661 | -786.32893677034 | -774.098751006756 | 0.000131972596291489 | 0.0140302751122379 | 0.123704180643248 |
| 91 | 91 | CML | homoharringtonine | HOXA11 | -228.605629520831 | -234.246387676797 | -227.339066944743 | 0.010277865932728 | 0.0172053191383773 | 0.195646984891322 |
| 92 | 92 | CML | homoharringtonine | JAK2 | 120.059423929617 | 120.032543202884 | 121.502556066442 | 0.0161503642380886 | 0.0183323446967447 | 0.227751215762542 |
| 93 | 93 | CML | homoharringtonine | MECOM | -212.643438032618 | -213.127209397309 | -208.090367042922 | 0.000370733405538894 | 0.00166949795263238 | 0.16431695155977 |
| 94 | 94 | CML | homoharringtonine | MSI2 | -635.873725953244 | -635.873725914625 | -632.638531343344 | 0.000653847891946169 | -0.000470276026351968 | 0.121412065093653 |
| 95 | 95 | CML | homoharringtonine | PCM1 | -236.729553581903 | -236.729553548793 | -235.817897062248 | 0.00158675203415708 | 0.000463677519980776 | 0.196637185701297 |
| 96 | 96 | CML | homoharringtonine | PDGFRB | -975.264308145635 | -975.26430803832 | -972.968263970559 | 0.00153446013912658 | 0.000411326766501463 | 0.11719051024994 |
| 97 | 97 | CML | homoharringtonine | RPL22 | -991.832631122594 | -991.83263107709 | -990.773247168961 | 0.00239558986407669 | 0.00127342516707984 | 0.116977577790631 |
| 98 | 98 | CML | homoharringtonine | SETBP1 | -392.591738520654 | -392.591738482283 | -392.421117843048 | 0.0158225263835899 | 0.0147154651035165 | 0.197434752826152 |
| 99 | 99 | CML | ponatinib | ABL1 | -855.492434270526 | -855.492434203374 | -855.181234028442 | 0.00526784780738673 | 0.00416504053429689 | 0.136383327264263 |
| 100 | 100 | CML | ponatinib | BCR | -297.529689627252 | -297.519898367277 | -294.165896560391 | 0.00209993134377694 | 0.000997050591801663 | 0.135345612590459 |