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+## About Dataset
+
+This repository holds the data from a cohort of pediatric patients with suspected appendicitis admitted with abdominal pain to Children’s Hospital St. Hedwig in Regensburg, Germany, between 2016 and 2021. Each patient has (potentially multiple) ultrasound (US) images, aka views, tabular data comprising laboratory, physical examination, scoring results and ultrasonographic findings extracted manually by the experts, and three target variables, namely, diagnosis, management and severity.
+
+This dataset was acquired in a retrospective study from a cohort of pediatric patients admitted with abdominal pain to Children’s Hospital St. Hedwig in Regensburg, Germany. Multiple abdominal B-mode ultrasound images were acquired for most patients, with the number of views varying from 1 to 15. The images depict various regions of interest, such as the abdomen’s right lower quadrant, appendix, intestines, lymph nodes and reproductive organs. Alongside multiple US images for each subject, the dataset includes information encompassing laboratory tests, physical examination results, clinical scores, such as Alvarado and pediatric appendicitis scores, and expert-produced ultrasonographic findings. Lastly, the subjects were labeled w.r.t. three target variables: diagnosis (appendicitis vs. no appendicitis), management (surgical vs. conservative) and severity (complicated vs. uncomplicated or no appendicitis). The study was approved by the Ethics Committee of the University of Regensburg (no. 18-1063-101, 18-1063_1-101 and 18-1063_2-101) and was performed following applicable guidelines and regulations.
+
+### Class Labels
+Diagnosis: [appendicitis, no appendicitis],
+Severity: [complicated, uncomplicated],
+Management: [conservative, primary surgical, secondary surgical, simultaneous appendectomy]
+
+**Variable Name -> Role -> Type -> Demographic -> Description**
+RBC_Count -> Feature -> Continuous -> -> The number of erythrocytes in a unit volume of blood
+Hemoglobin -> Feature -> Continuous -> -> Hemoglobin level; a red protein in the red blood cells that contains iron and is responsible for transporting oxygen
+RDW -> Feature -> Continuous -> -> A blood test that measures the differences in the volume and size of the erythrocytes
+Thrombocyte_Count -> Feature -> Integer -> -> The number of platelets in a unit volume of blood
+Ketones_in_Urine -> Feature -> Categorical -> -> Presence of ketone bodies in urine, e.g. in case of anorexia
+RBC_in_Urine -> Feature -> Categorical -> -> Blood in urine
+WBC_in_Urine -> Feature -> Categorical -> -> Leucocytes in urine, e.g., in case of infection
+CRP -> Feature -> Integer -> -> Protein produced by the liver, elevated in case of inflammation, infection, or injury
+Dysuria -> Feature -> Binary -> -> Pain or other difficulty during urination
+Stool -> Feature -> Categorical -> -> Characteristics of bowel movements
+Peritonitis -> Feature -> Categorical -> -> Spasm of abdominal wall muscles detected on palpation, usually a result of inflammation
+Psoas_Sign -> Feature -> Categorical -> -> Abdominal pain produced by extension of the hip
+Ipsilateral_Rebound_Tenderness -> Feature -> Categorical -> -> A state in which pain of the ipsilateral side is felt on the release of pressure over the abdomen
+US_Performed -> Feature -> Categorical -> -> If an abdominal ultrasonography was performed or not
+US_Number -> Other -> Integer -> ->
+Free_Fluids -> Feature -> Categorical -> -> Free fluids inside the abdomen
+Appendix_Wall_Layers -> Feature -> Categorical -> -> Distribution and characteristics of appendix layers, e.g., irregular in case of an increasing inflammation
+Target_Sign -> Feature -> Categorical -> -> Axial image of appendix with a fluid-filled center surrounded by echogenic mucosa and submucosa and hypoechoic muscularis
+Appendicolith -> Feature -> Categorical -> -> Presence of fecalith in the appendix, e.g. acoustic shadow
+Perfusion -> Feature -> Categorical -> -> Blood flow to the appendix wall
+Perforation -> Feature -> Categorical -> -> Signs of appendix perforation in US
+Surrounding_Tissue_Reaction -> Feature -> Categorical -> -> Inflammation signs in tissue (i.a. in omentum/fat tissue) surrounding appendix
+Appendicular_Abscess -> Feature -> Categorical -> -> Appendiceal mass
+Abscess_Location -> Feature -> Categorical -> -> Location of the abcess intraperitoneal
+Pathological_Lymph_Nodes -> Feature -> Binary -> -> Enlarged and inflamed intra-abdominal lymph nodes
+Variable Name -> Role -> Type -> Demographic -> Description -> Units
+Lymph_Nodes_Location -> Feature -> Categorical -> -> The location of pathological lymph nodes in the abdomen
+Bowel_Wall_Thickening -> Feature -> Binary -> -> Edema of the intestinal wall, > 2-3 mm for small bowel wall thickening
+Conglomerate_of_Bowel_Loops -> Feature -> Binary -> -> Small intestine conglomerate as sign of intraperitoneal inflammation
+Ileus -> Feature -> Categorical -> -> Sonographic signs of paralytic ileus (e.g., dilated intestinal loops, pendulum peristalsis or absence of peristalsis)
+Coprostasis -> Feature -> Categorical -> -> Fecal impaction in the colon
+Meteorism -> Feature -> Categorical -> -> Accumulation of gas in the intestine
+Enteritis -> Feature -> Categorical -> -> Sonographic features of gastroenteritis, e.g. wall thickening of ileum, increased peristalsis
+Gynecological_Findings -> Feature -> Categorical -> -> Gynaecological abnormalities, e.g. cysts, ovarial torsion
+RBC_Count -> Feature -> Continuous -> -> The number of erythrocytes in a unit volume of blood
+Hemoglobin -> Feature -> Continuous -> -> Hemoglobin level; a red protein in the red blood cells that contains iron and is responsible for transporting oxygen
+RDW -> Feature -> Continuous -> -> A blood test that measures the differences in the volume and size of the erythrocytes
+Thrombocyte_Count -> Feature -> Integer -> -> The number of platelets in a unit volume of blood
+Ketones_in_Urine -> Feature -> Categorical -> -> Presence of ketone bodies in urine, e.g. in case of anorexia
+RBC_in_Urine -> Feature -> Categorical -> -> Blood in urine
+WBC_in_Urine -> Feature -> Categorical -> -> Leucocytes in urine, e.g., in case of infection
+CRP -> Feature -> Integer -> -> Protein produced by the liver, elevated in case of inflammation, infection, or injury
+Dysuria -> Feature -> Binary -> -> Pain or other difficulty during urination
+Stool -> Feature -> Categorical -> -> Characteristics of bowel movements
+Peritonitis -> Feature -> Categorical -> -> Spasm of abdominal wall muscles detected on palpation, usually a result of inflammation
+Psoas_Sign -> Feature -> Categorical -> -> Abdominal pain produced by extension of the hip
+Ipsilateral_Rebound_Tenderness -> Feature -> Categorical -> -> A state in which pain of the ipsilateral side is felt on the release of pressure over the abdomen
+US_Performed -> Feature -> Categorical -> -> If an abdominal ultrasonography was performed or not
+US_Number -> Other -> Integer -> ->
+Free_Fluids -> Feature -> Categorical -> -> Free fluids inside the abdomen
+Appendix_Wall_Layers -> Feature -> Categorical -> -> Distribution and characteristics of appendix layers, e.g., irregular in case of an increasing inflammation
+Target_Sign -> Feature -> Categorical -> -> Axial image of appendix with a fluid-filled center surrounded by echogenic mucosa and submucosa and hypoechoic muscularis
+Appendicolith -> Feature -> Categorical -> -> Presence of fecalith in the appendix, e.g. acoustic shadow
+Perfusion -> Feature -> Categorical -> -> Blood flow to the appendix wall
+Perforation -> Feature -> Categorical -> -> Signs of appendix perforation in US
+Surrounding_Tissue_Reaction -> Feature -> Categorical -> -> Inflammation signs in tissue (i.a. in omentum/fat tissue) surrounding appendix
+Appendicular_Abscess -> Feature -> Categorical -> -> Appendiceal mass
+Abscess_Location -> Feature -> Categorical -> -> Location of the abcess intraperitoneal
+Pathological_Lymph_Nodes -> Feature -> Binary -> -> Enlarged and inflamed intra-abdominal lymph nodes
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