<table><tbody><tr><td><table cellpadding="2" cellspacing="0" width="600"><tbody><tr bgcolor="#cccccc" valign="top"><td colspan="2"><table width="600"><tbody><tr><td><strong class="acc" id="GSE250122"><a href="/geo/query/acc.cgi?acc=GSE250122" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_recenter)">Series GSE250122</a></strong></td>

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<td align="right" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_gds)"><a href="/gds/?term=GSE250122[Accession]">Query DataSets for GSE250122</a></td>

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<tr valign="top"><td>Status</td>

<td>Public on Mar 20, 2024</td>

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<tr valign="top"><td nowrap="">Title</td>

<td style="text-align: justify">The impact of endurance exercise on human skeletal muscle transcriptome</td>

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<tr valign="top"><td nowrap="">Organism</td>

<td><a href="/Taxonomy/Browser/wwwtax.cgi?mode=Info&amp;id=9606" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_organismus)">Homo sapiens</a></td>

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<tr valign="top"><td nowrap="">Experiment type</td>

<td>Expression profiling by array<br></td>

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<tr valign="top"><td nowrap="">Summary</td>

<td style="text-align: justify">The aim of this study was to elucidate the transcriptional signatures that distinguish the endurance-trained and the untrained muscle in healthy adult young males, both at baseline as well as in response to an acute bout of exercise.<br></td>

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<tr valign="top"><td nowrap="">Overall design</td>

<td style="text-align: justify">We characterized baseline differences as well as acute exercise-induced transcriptome responses in vastus lateralis biopsy specimen of endurance-trained athletes (ET; n = 8; age, 25.4 ±3.8; VO2max, 67.2 ±8.9 ml/min/kg) and sedentary untrained volunteers (SED; n = 8; age, 22.6 ±2.8; VO2max, 40.3 ±7.6 ml/min/kg) using Human Genome U219 (HG-U219) microarray platform. The acute exercise protocol that consisted of 60 min of high intensity cycling exercise on a cycle ergometer at a power requiring 80% of the individual VO2max (including 10 min of initial warm-up cycling at 60% VO2max). Baseline samples of the resting muscle were obtained 24 hours before the acute exercise protocol was started. Post exercise biopsies were taken at 30 min (+30') and at 3 hours (+3 h) after cessation of acute cycling exercise.<br></td>

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<tr valign="top"><td>Contributor(s)</td>

<td><a href="/pubmed/?term=Beiter T[Author]">Beiter T</a>, <a href="/pubmed/?term=Zügel M[Author]">Zügel M</a>, <a href="/pubmed/?term=Nieß AM[Author]">Nieß AM</a>, <a href="/pubmed/?term=Mooren FC[Author]">Mooren FC</a>, <a href="/pubmed/?term=Steinacker J[Author]">Steinacker J</a></td>

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<tr valign="top"><td nowrap="">Citation(s)</td>

<td><span class="pubmed_id" id="38474128"><!--?xml version="1.0" encoding="UTF-8"?-->

<div class="PubmedCitation"><ul><li><span class="authors">Beiter T, Zügel M, Hudemann J, Schild M et al. </span><span class="title">The Acute, Short-, and Long-Term Effects of Endurance Exercise on Skeletal Muscle Transcriptome Profiles. </span><span class="source">Int J Mol Sci</span> 2024 Mar 1;25(5). PMID:&nbsp;<a title="Link to PubMed record" href="https://www.ncbi.nlm.nih.gov/pubmed/38474128">38474128</a></li></ul></div>

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<tr bgcolor="#eeeeee" valign="top"><td>Submission date</td>

<td>Dec 13, 2023</td>

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<tr bgcolor="#eeeeee" valign="top"><td>Last update date</td>

<td>Mar 21, 2024</td>

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<tr bgcolor="#eeeeee" valign="top"><td>Contact name</td>

<td>Thomas Beiter</td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">E-mail(s)</td>

<td><a href="mailto:thomas.beiter@med.uni-tuebingen.de">thomas.beiter@med.uni-tuebingen.de</a><br></td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Phone</td>

<td style="text-align: justify">4970712985233<br></td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Organization name</td>

<td style="text-align: justify">Eberhard-Karls-University Tübingen<br></td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Department</td>

<td style="text-align: justify">Sports Medicine<br></td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Street address</td>

<td style="text-align: justify">Hoppe-Seyler-Str. 6<br></td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">City</td>

<td style="text-align: justify">Tübingen</td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">ZIP/Postal code</td>

<td style="text-align: justify">72076</td>

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<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Country</td>

<td style="text-align: justify">Germany</td>

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<tr valign="top"><td nowrap="">&nbsp;</td>

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