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| Status |
Public on Dec 31, 2019 |
| Title |
Gene expression of peripheral blood leukocytes in athletes |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Probiotics may alter stress sensitivity by modulating the gut-brain axis. The heat-inactivated, enteric-colonizing Lactobacillus gasseri, CP2305 (paraprobiotic CP2305), has been shown to ameliorate psychological stress-related symptoms. This study was designed to reveal the beneficial effects of paraprobiotic CP2305 on top athletes experiencing physical and mental stresses.
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| Overall design |
Forty-nine male university Ekiden runners were randomly assigned to two groups. These athletes consumed a test beverage containing paraprobiotic CP2305 or placebo daily, for 12 weeks. Before and 12 weeks after beverage consumption, the gene expression profiles in peripheral blood leukocytes were assesed by Agilent microarray (SurePrint G3 Human GE 8×60k).
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| Contributor(s) |
Nishida K, Sawada D |
| Citation |
Daisuke Sawada, Yuki Kuwano, Hiroki Tanaka, Susumu Hara, Yoshihide Uchiyama, Tomonori Sugawara, Shigeru Fujiwara, Kazuhito Rokutan, and Kensei Nishida. Daily intake of Lactobacillus gasseri CP2305 relieves fatigue and stress-related symptoms in male university Ekiden runners: A double-blind, randomized, and placebo-controlled clinical trial. Journal of Functional Foods 2019;57:465-476. doi:10.1016/j.jff.2019.04.022
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| Submission date |
Nov 19, 2018 |
| Last update date |
Apr 01, 2020 |
| Contact name |
Kensei Nishida |
| E-mail(s) |
knishida@tokushima-u.ac.jp
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| Organization name |
Tokushima University Graduate school
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| Street address |
3-18-15 Kuramoto-cho
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| City |
Tokushima |
| State/province |
Tokushima |
| ZIP/Postal code |
7708503 |
| Country |
Japan |
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