<table><tbody><tr><td><table cellpadding="2" cellspacing="0" width="600"><tbody><tr bgcolor="#cccccc" valign="top"><td colspan="2"><table width="600"><tbody><tr><td><strong class="acc" id="GSE213803"><a href="/geo/query/acc.cgi?acc=GSE213803" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_recenter)">Series GSE213803</a></strong></td>

<td></td>

<td align="right" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_gds)"><a href="/gds/?term=GSE213803[Accession]">Query DataSets for GSE213803</a></td>

</tr></tbody></table></td></tr>

<tr valign="top"><td>Status</td>

<td>Public on May 31, 2023</td>

</tr>

<tr valign="top"><td nowrap="">Title</td>

<td style="text-align: justify">A single-cell multi-modal ATAC + gene expression sequencing in tendinopathy</td>

</tr>

<tr valign="top"><td nowrap="">Organism</td>

<td><a href="/Taxonomy/Browser/wwwtax.cgi?mode=Info&amp;id=9606" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_organismus)">Homo sapiens</a></td>

</tr>

<tr valign="top"><td nowrap="">Experiment type</td>

<td>Expression profiling by high throughput sequencing<br>Genome binding/occupancy profiling by high throughput sequencing<br></td>

</tr>

<tr valign="top"><td nowrap="">Summary</td>

<td style="text-align: justify">As people become more motivated to exercise regularly and stay healthy, tendinopathy is a common problem in both active athletes and inactive individuals, which imposes a considerable social and economic burden. Here we provide a single-cell multi-modal ATAC + gene expression sequencing in tendinopathy. We have identified pathways and genes regulated in tendinopathy samples that will help contribute to further investigation into the development and molecular hallmarks of tendinopathy.<br></td>

</tr>

<tr valign="top"><td nowrap="">&nbsp;</td>

<td></td>

</tr>

<tr valign="top"><td nowrap="">Overall design</td>

<td style="text-align: justify">Single-cell multi-modal ATAC + gene expression sequencing of human tendinopathy<br></td>

</tr>

<tr valign="top"><td nowrap="">&nbsp;</td>

<td></td>

</tr>

<tr valign="top"><td>Contributor(s)</td>

<td><a href="/pubmed/?term=Guo J[Author]">Guo J</a>, <a href="/pubmed/?term=Liang T[Author]">Liang T</a>, <a href="/pubmed/?term=Tang K[Author]">Tang K</a></td>

</tr>

<tr valign="top"><td nowrap="">Citation(s)</td>

<td><span class="pubmed_id" id="37223090"><!--?xml version="1.0" encoding="UTF-8"?-->

<div class="PubmedCitation"><ul><li><span class="authors">Guo J, Tang H, Huang P, Ye X et al. </span><span class="title">Integrative single-cell RNA and ATAC sequencing reveals that the FOXO1-PRDX2-TNF axis regulates tendinopathy. </span><span class="source">Front Immunol</span> 2023;14:1092778. PMID:&nbsp;<a title="Link to PubMed record" href="https://www.ncbi.nlm.nih.gov/pubmed/37223090">37223090</a></li></ul></div>

</span></td>

</tr>

<tr valign="top"><td colspan="2"><span id="geo2r"></span> <span id="rnaseq_counts"></span></td></tr>

<tr bgcolor="#eeeeee" valign="top"><td>Submission date</td>

<td>Sep 20, 2022</td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td>Last update date</td>

<td>Jun 01, 2023</td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td>Contact name</td>

<td>JUNFENG GUO</td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td nowrap="">E-mail(s)</td>

<td><a href="mailto:guojfyd@tmmu.edu.cn">guojfyd@tmmu.edu.cn</a><br></td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Phone</td>

<td style="text-align: justify">+8613167966525<br></td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Organization name</td>

<td style="text-align: justify">Southwest Hospital, Third Military Medical University<br></td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Department</td>

<td style="text-align: justify">Department of Orthopedics/Sports Medicine Center<br></td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Street address</td>

<td style="text-align: justify">No. 30, Gaotan Yanzheng Street,<br></td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td nowrap="">City</td>

<td style="text-align: justify">Chongqing</td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td nowrap="">State/province</td>

<td style="text-align: justify">Chongqing</td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td nowrap="">ZIP/Postal code</td>

<td style="text-align: justify">400038</td>

</tr>

<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Country</td>

<td style="text-align: justify">China</td>

</tr>

<tr valign="top"><td nowrap="">&nbsp;</td>

<td></td>

</tr>

<tr valign="top"><td>Platforms (2)</td>

<td onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_recenter)"><table cellpadding="3" style="position:relative;top:-5px;left:-5px"><tbody><tr><td valign="top"><a href="/geo/query/acc.cgi?acc=GPL20301" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_recenter)">GPL20301</a></td>

<td valign="top">Illumina HiSeq 4000 (Homo sapiens)</td>

</tr>

<tr><td valign="top"><a href="/geo/query/acc.cgi?acc=GPL24676" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_recenter)">GPL24676</a></td>

<td valign="top">Illumina NovaSeq 6000 (Homo sapiens)</td>

</tr>

</tbody></table></td>

</tr>

</tbody></table>