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| Status |
Public on May 31, 2023 |
| Title |
A single-cell multi-modal ATAC + gene expression sequencing in tendinopathy |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
As people become more motivated to exercise regularly and stay healthy, tendinopathy is a common problem in both active athletes and inactive individuals, which imposes a considerable social and economic burden. Here we provide a single-cell multi-modal ATAC + gene expression sequencing in tendinopathy. We have identified pathways and genes regulated in tendinopathy samples that will help contribute to further investigation into the development and molecular hallmarks of tendinopathy.
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| Overall design |
Single-cell multi-modal ATAC + gene expression sequencing of human tendinopathy
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| Contributor(s) |
Guo J, Liang T, Tang K |
| Citation(s) |
- Guo J, Tang H, Huang P, Ye X et al. Integrative single-cell RNA and ATAC sequencing reveals that the FOXO1-PRDX2-TNF axis regulates tendinopathy. Front Immunol 2023;14:1092778. PMID: 37223090
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| Submission date |
Sep 20, 2022 |
| Last update date |
Jun 01, 2023 |
| Contact name |
JUNFENG GUO |
| E-mail(s) |
guojfyd@tmmu.edu.cn
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| Phone |
+8613167966525
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| Organization name |
Southwest Hospital, Third Military Medical University
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| Department |
Department of Orthopedics/Sports Medicine Center
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| Street address |
No. 30, Gaotan Yanzheng Street,
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| City |
Chongqing |
| State/province |
Chongqing |
| ZIP/Postal code |
400038 |
| Country |
China |
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| Platforms (2) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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