Context

This dataset is from the clinicaltrails.gov website, specifically searched for platinum-resistant ovarian cancer in January 2022.

dataset source:
https://clinicaltrials.gov/ct2/results?cond=Platinum-resistant+Ovarian+Cancer&term=&cntry=&state=&city=&dist=

Ovarian cancer Wikipedia:
https://en.wikipedia.org/wiki/Ovarian_cancer

Ovarian cancer (OC) is the seventh most common cancer among women with an approximately 70 percent recurrence rate. Despite the high recurrence probability, most diagnoses happen in an advanced stage because of lack of symptoms and preventative measures.

The initial and most effective treatment against OC, followed by the surgery, remains to be platinum-based chemotherapy typically given in 6 rounds. However, in Platinum-Resistant Ovarian Cancer (PROC) where relapse happens within 6 months after the last round of chemotherapy treatment options become limited to non-platinum-based agents with a low treatment response rate. Active research is therefore in a critical need for PROC and OC
patients as the most relapsed patients, which are then considered incurable, eventually also develop resistance against platinum-based treatments.

PROC patients are strongly recommended to participate in a clinical trial. This dataset contains past and ongoing clinical trials for PROC. The goal is to identify intervention trends, as well as trial characteristics.

Clinical Trials require to undergo 3 phases. Trials meeting the superior outcomes will get FDA approval for the market.
Please refer to the following link for clinical trial phase designs details:
https://en.wikipedia.org/wiki/Phases_of_clinical_research#Phase_0

Content

Rank - row numbers
NCT Number - Clinical Trial identification number. To see the trail details simply google this id.
Title - Trial title
Acronym - Trial acronym. Some trials are missing in this column despite having one. They are usually written along with the title instead.
Status - Trial status.
Study Results - indicates whether the trial posted the result. Some trials might not have posted the trial but links the related papers.
Conditions - Medical conditions for a given trial. Might be more than one.
Interventions - Type of interventions used. Typically drugs but could also contain Devices, Radiation, etc.
Outcome Measures - Trial outcome goals.
Sponsor/Collaborators - Trial Sponsors and/or Collaborators
Gender - Subject gender requirement
Age - Subject age requirement
Phases - Current Trial Phase.
Enrollment - Number of participating patients
Funded Bys - Funding agencies
Study Type - Type of experiment
Study Designs - Experiment design details
Other IDs - Other relative IDs
Start Date - Trial Start Date
Primary Completion Date - the date of the last study visit where data was collected for the primary study outcome(s)
Completion Date - the date of the last study visit where data was collected for any of the study outcomes.
First Posted - First posted date
Results First Posted - Results posted date
Last Update Posted - Last site update date
Locations - Participating Locations
Study Documents - Relative documents
URL - Trial URL

Acknowledgements

The world is in forever debt for the PROC patients and family f for contributing to the research.