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+<table><tbody><tr><td><table cellpadding="2" cellspacing="0" width="600"><tbody><tr bgcolor="#cccccc" valign="top"><td colspan="2"><table width="600"><tbody><tr><td><strong class="acc" id="GSE282896"><a href="/geo/query/acc.cgi?acc=GSE282896" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_recenter)">Series GSE282896</a></strong></td>
+<td></td>
+<td align="right" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_gds)"><a href="/gds/?term=GSE282896[Accession]">Query DataSets for GSE282896</a></td>
+</tr></tbody></table></td></tr>
+<tr valign="top"><td>Status</td>
+<td>Public on Apr 02, 2025</td>
+</tr>
+<tr valign="top"><td nowrap="">Title</td>
+<td style="text-align: justify">Ferroptosis Induced by Omega-3 Docosahexaenoic Acid (DHA) and Erastin in Control MDA-MB-231 Cells (sh-LUC) and MDA-MB-231 Cells with knockdown of IGFBP6 gene (sh-IGFBP6)</td>
+</tr>
+<tr valign="top"><td nowrap="">Organism</td>
+<td><a href="/Taxonomy/Browser/wwwtax.cgi?mode=Info&amp;id=9606" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_organismus)">Homo sapiens</a></td>
+</tr>
+<tr valign="top"><td nowrap="">Experiment type</td>
+<td>Expression profiling by high throughput sequencing<br></td>
+</tr>
+<tr valign="top"><td nowrap="">Summary</td>
+<td style="text-align: justify">In this study, we further elucidate the mechanism of action of one of the most effective antitumor PUFAs, ω-3 docosahexaenoic acid, on MDA-MB-231 breast cancer cells, including those with IGFBP6 knockdown. Additionally, we analyzed the effect of reduced IGFBP6 gene expression on the mechanism of ferroptosis in MDA-MB-231 breast cancer cells under the influence of the canonical ferroptosis inducer erastin.<br></td>
+</tr>
+<tr valign="top"><td nowrap="">&nbsp;</td>
+<td></td>
+</tr>
+<tr valign="top"><td nowrap="">Overall design</td>
+<td style="text-align: justify">Total RNA profiles of control MDA-MB-231 cells (sh-LUC) and MDA-MB-231cells with knockdown of IGFBP6 gene (sh-IGFBP6) treated with erastin and omega-3 docosahexaenoic Acid (DHA).<br></td>
+</tr>
+<tr valign="top"><td nowrap="">&nbsp;</td>
+<td></td>
+</tr>
+<tr valign="top"><td>Contributor(s)</td>
+<td><a href="/pubmed/?term=Nikulin S[Author]">Nikulin S</a>, <a href="/pubmed/?term=Razumovskaya A[Author]">Razumovskaya A</a></td>
+</tr>
+<tr valign="top"><td>Citation missing</td>
+<td class="message" id="pmidCell">Has this study been published? Please <a href="/geo/submitter">login</a> to update or <a href="mailto:geo@ncbi.nlm.nih.gov?subject=Citation for GSE282896 [not logged in]&amp;body=Thank you very much for helping to keep GEO citation links up-to-date. Please enter the PubMed ID (PMID) or full citation for GSE282896 below, and we will update the record accordingly within the next day or two. The PubMed ID or citation is:
+">notify GEO</a>.</td>
+</tr>
+<tr valign="top"><td colspan="2"><span id="geo2r"></span> <span id="rnaseq_counts"></span></td></tr>
+<tr bgcolor="#eeeeee" valign="top"><td>Submission date</td>
+<td>Nov 26, 2024</td>
+</tr>
+<tr bgcolor="#eeeeee" valign="top"><td>Last update date</td>
+<td>Apr 02, 2025</td>
+</tr>
+<tr bgcolor="#eeeeee" valign="top"><td>Contact name</td>
+<td>Sergey Nikulin</td>
+</tr>
+<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Organization name</td>
+<td style="text-align: justify">HSE University<br></td>
+</tr>
+<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Department</td>
+<td style="text-align: justify">Faculty of Biology and Biotechnology<br></td>
+</tr>
+<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Lab</td>
+<td style="text-align: justify">International Laboratory of Microphysiological Systems<br></td>
+</tr>
+<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Street address</td>
+<td style="text-align: justify">7, Vavilova st.<br></td>
+</tr>
+<tr bgcolor="#eeeeee" valign="top"><td nowrap="">City</td>
+<td style="text-align: justify">Moscow</td>
+</tr>
+<tr bgcolor="#eeeeee" valign="top"><td nowrap="">ZIP/Postal code</td>
+<td style="text-align: justify">117312</td>
+</tr>
+<tr bgcolor="#eeeeee" valign="top"><td nowrap="">Country</td>
+<td style="text-align: justify">Russia</td>
+</tr>
+<tr valign="top"><td nowrap="">&nbsp;</td>
+<td></td>
+</tr>
+<tr valign="top"><td>Platforms (1)</td>
+<td onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_recenter)"><table cellpadding="3" style="position:relative;top:-5px;left:-5px"><tbody><tr><td valign="top"><a href="/geo/query/acc.cgi?acc=GPL28337" onmouseout="onLinkOut('HelpMessage' , geo_empty_help)" onmouseover="onLinkOver('HelpMessage' , geoaxema_recenter)">GPL28337</a></td>
+<td valign="top">DNBSEQ-G50 (Homo sapiens)</td>
+</tr></tbody></table></td>
+</tr>
+</td></tr></tbody></table>
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