Alongside ailments resulting from hepatitis B, cervical cancer has a strong claim to be the world’s deadliest vaccine-preventable disease. Most illnesses for which effective vaccines for children are widely available no longer threaten public health. But in 2020, 14 years after the advent of a jab that prevents almost all cases, cervical cancer still killed 342,000 women. If take-up of the vaccine rose—a goal about which there are new grounds for hope—this cancer could be nearly eliminated.