PTEN phosphatase and tensin homolog[Homo sapiens]
Gene ID: 5728, updated on 1-May-2023
SUMMARY
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Official Symbol: PTEN (provided by HGNC)
Official full name: phosphatase and tensin homolog (provided by HGNC)
Primary source: HGNC:HGNC:9588
See related: Ensembl:ENSG00000171862; MIM:601728; AllianceGenome:HGNC:9588
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: BZS; DEC; CWS1; GLM2; MHAM; TEP1; MMAC1; PTEN1; 10q23del; PTENbeta
Summary: This gene was identified as a tumor suppressor that is mutated in a large number
of cancers at high frequency. The protein encoded by this gene is a
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like
domain as well as a catalytic domain similar to that of the dual specificity
protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases,
this protein preferentially dephosphorylates phosphoinositide substrates. It
negatively regulates intracellular levels of
phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor
suppressor by negatively regulating AKT/PKB signaling pathway. The use of a
non-canonical (CUG) upstream initiation site produces a longer isoform that
initiates translation with a leucine, and is thought to be preferentially
associated with the mitochondrial inner membrane. This longer isoform may help
regulate energy metabolism in the mitochondria. A pseudogene of this gene is
found on chromosome 9. Alternative splicing and the use of multiple translation
start codons results in multiple transcript variants encoding different isoforms.
[provided by RefSeq, Feb 2015]
Annotation information: Annotation category: suggests misassembly
Orthologsall (/gene/?Term=ortholog_gene_5728[group]), mouse (https://www.ncbi.nlm.nih.gov/gene/19211)
GENOMIC CONTEXT
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Location: 10q23.31
Annotation release Status Assembly Chromosome Location
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RS_2023_03 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (87863625..87971930)
RS_2023_03 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (88747528..88855830)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (89623382..89731687)
Exont count: 10
BIBLIOGRAPHY
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Related Articles in PubMed
1. Longitudinal Analysis of Cancer Risk in Children and Adults With Germline PTEN
Variants. Yehia L, . JAMA Netw Open, 2023 Apr 3, PMID 37093598., Free PMC Article(s): PMC10126871
2. Overexpression of the PTEN Gene in Myocardial Tissues of Coronary Bypass Surgery
Patients. Tahtasakal R, . Arq Bras Cardiol, 2023, PMID 37042855.
3. Pan-cancer genomic analysis shows hemizygous PTEN loss tumors are associated with
immune evasion and poor outcome. Vidotto T, . Sci Rep, 2023 Mar 28, PMID
36977733., Free PMC Article(s): PMC10050165
4. miR-19-3p Targets PTEN to Regulate Cervical Cancer Cell Proliferation, Invasion,
and Autophagy. Wang W, . Genet Res (Camb), 2023, PMID 36908850., Free PMC Article(s): PMC10005872
5. Nuclear PTEN's Functions in Suppressing Tumorigenesis: Implications for Rare
Cancers. Langdon CG. Biomolecules, 2023 Jan 30, PMID 36830628., Free PMC Article(s): PMC9953540
6. The PTEN-associated immune prognostic signature reveals the landscape of the
tumor microenvironment in glioblastoma. Yu J, . J Neuroimmunol, 2023 Mar 15, PMID
36791582.
<pre>
PHENOTYPES
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Review eQTL and phenotype association data in this region using PheGenI
http://www.ncbi.nlm.nih.gov/gap/PheGenI?chr=10&from=87863624&fromto=87863624+87971929&tab=0
Professional guidelines
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Professional guideline
ACMG 2013
The ACMG recommends that laboratories performing clinical sequencing seek and report mutations in PTEN that are pathogenic or expected to be pathogenic.
Guideline(http://www.acmg.net/docs/ACMG_Releases_Highly-Anticipated_Recommendations_on_Incidental_Findings_in_Clinical_Exome_and_Genome_Sequencing.pdf)
PubMed(/pubmed/23788249)
Associated conditions
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Description Tests
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Cowden syndrome 1
MedGen: CN072330 OMIM: 158350 GeneReviews: PTEN Hamartoma Tumor Syndrome
Familial meningioma
MedGen: C3551915 OMIM: 607174 GeneReviews: MN1 C-Terminal Truncation Syndrome
Genome-wide association study of chronic periodontitis in a general German population.
GeneReviews: <span>Not available</span>
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
GeneReviews: <span>Not available</span>
Glioma susceptibility 2
MedGen: C2751642 OMIM: 613028 GeneReviews: <span>Not available</span>
Macrocephaly-autism syndrome
MedGen: C1854416 OMIM: 605309 GeneReviews: <span>Not available</span>
Malignant tumor of prostate
MedGen: C0376358 OMIM: 176807 GeneReviews: <span>Not available</span>
PTEN hamartoma tumor syndrome
MedGen: C1959582 GeneReviews: PTEN Hamartoma Tumor Syndrome
Copy number response
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Copy number response
Triplosensitivity
No evidence available (Last evaluated 2020-06-24)
ClinGen Genome Curation Page(https://www.ncbi.nlm.nih.gov/projects/dbvar/ISCA/isca_gene.cgi?sym=PTEN)Haploinsufficency
Sufficient evidence for dosage pathogenicity (Last evaluated 2020-06-24)
ClinGen Genome Curation Page(https://www.ncbi.nlm.nih.gov/projects/dbvar/ISCA/isca_gene.cgi?sym=PTEN)
PubMed(/pubmed/21194675,32003824)</pre>
VARIATION
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See variants in ClinVar, http://130.14.22.59/sites/gene/clinvar/?term=PTEN[gene]
See studies and variants in dbVar, http://130.14.22.59/sites/gene
See Variation Viewer (GRCh37.p13), http://130.14.22.59/sites/gene/variation/view/?q=5728[geneid]&assm=GCF_000001405.25
See Variation Viewer (GRCh38), http://130.14.22.59/sites/gene/variation/view/?q=5728[geneid]<pre/><pre>
Genotypes
See SNP Geneview Report, http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2FSNP%2Fsnp_ref.cgi%3FlocusId%3D5728
See 1000 Genomes Browser (GCF_000001405.25), http://130.14.22.59/sites/gene/variation/tools/1000genomes/?q=5728[geneid]&assm=GCF_000001405.25</pre>
HIV-1 INTERACTIONS
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Replication interactions
Interaction Pubs
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Knockdown of phosphatase and tensin homolog (PTEN) by shRNA library screening inhibits HIV-1 replication in cultured Jurkat T-cells 19460752Protein interactions
Protein Gene Interaction Pubs
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/protein/28876544 /gene/155971 Silencing PTEN gene by siRNA prevents HIV-1 gp120-mediated neurotoxic effects 21234828
/protein/28872818 /gene/156110 HIV-1 Nef- and KSHV K1-induced angiogenesis is regulated by miR-718-mediated target of PTEN 25104021
/protein/9629358 /gene/155871 HIV-1 Tat induces phosphorylation of PI3K, AKT, PTEN, and GSK-3beta activating PI3K and AKT and inactivating PTEN and GSK-3beta in vIL-6 expressing cells 23301033
/protein/9629358 /gene/155871 Pro-survival effects of intracellular HIV-1 Tat in a microglial cell line is attributed to activation of the PI-3-kinase (PI3K)/Akt pathway via decreasing expression of PTEN, a negative regulator of the PI-3-K pathway 21763505,19526283,17157319
/protein/9629358 /gene/155871 HIV-1 Tat upregulates PTEN expression in Tat-infected Jurkat T cells 22422068,20862322,19050264
/protein/9629358 /gene/155871 Inhibiting phosphatidylinositol 3-kinase by overexpressing PTEN phosphatase enhances HIV-1 Tat transactivation of the viral LTR promoter 12077252
/protein/28876542 /gene/155030 HIV-1 MA proteins from HIV-1 infected non-Hodgkin lymphoma patients activates AKT1 and PTEN 26578780
/protein/28876542 /gene/155030 HIV-1 p17 and its C-terminal truncated form of p17 (p17delta36) differentially regulate Akt phosphorylation by reducing and increasing phosphorylation levels of PTEN, respectively 21423810
/protein/28876542 /gene/155030 HIV-1 p17-induced activation of PTEN is mediated by RhoA-associated kinase (ROCK) 21423810
Go to the HIV-1, Human Interaction Database: http://130.14.22.59/genome/viruses/retroviruses/hiv-1/interactions/
INTERACTION
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Description of Gene Interaction table
Product Interactant Other Gene Complex Source Pubs
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MAGI3 interacts with PTEN/MMAC.
NP_000305.2 NP_066016.1 MAGI3 BIND PMID: 10748157
PTEN interacts with PICT-1.
NP_000305.2 NP_056525.1 NOP53 BIND PMID: 15355975
PTEN interacts with Rock1.
NP_000305.2 NP_005397.1 ROCK1 BIND PMID: 15793569
P60484 P31749 AKT1 HPRD PMID: 12297295,12077256,10866658
P60484 P03950 ANG HPRD PMID: 16169070
P60484 P10275 AR HPRD PMID: 15205473
caveolin-1 interacts with PTEN.
P60484 NP_001744.2 CAV1 BIND PMID: 12176037
P60484 Q03135 CAV1 HPRD PMID: 12176037
P60484 P05060 CHGB HPRD PMID: 16169070
P60484 Q7L5N1 COPS6 HPRD PMID: 16169070
P60484 P68400 CSNK2A1 HPRD PMID: 12297295
P60484 P19784 CSNK2A2 HPRD PMID: 12297295
P60484 Q12959 DLG1 HPRD PMID: 10646847
P60484 P69905 HBA2 HPRD PMID: 16169070
P60484 Q86UL8 MAGI2 HPRD PMID: 10760291
P60484 MAGI-3 MAGI3 HPRD PMID: 10748157
P60484 Q9Y2H9 MAST1 HPRD PMID: 15951562
P60484 Q6P0Q8 MAST2 HPRD PMID: 15951562
P60484 O60307 MAST3 HPRD PMID: 15951562
P60484 Q14764 MVP HPRD PMID: 12177006
P60484 O14745 NHERF1 HPRD PMID: 16456542
P60484 Q15599 NHERF2 HPRD PMID: 16456542
P60484 P62136 PPP1CA HPRD PMID: 17274640
P60484 P49023 PXN HPRD PMID: 11857088
P60484 Q15831 STK11 HPRD PMID: 15987703
P60484 P04637 TP53 HPRD PMID: 12620407
P60484 P63279 UBE2I HPRD PMID: 12620973
P60484 P68036 UBE2L3 HPRD PMID: 12620973
P60484 Q9BVJ6 UTP14A HPRD PMID: 16169070
Two-hybrid
BioGRID:111700 BioGRID:114984 AATK BioGRID PMID: 28065597
Reconstituted Complex
BioGRID:111700 BioGRID:115372 ABCF2 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:106549 ACACA BioGRID PMID: 21532586
Affinity Capture-MS
BioGRID:111700 BioGRID:106550 ACACB BioGRID PMID: 21532586
Affinity Capture-MS
BioGRID:111700 BioGRID:117073 ACAP2 BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:106556 ACAT1 BioGRID PMID: 32249768
Affinity Capture-MS
BioGRID:111700 BioGRID:106568 ACP1 BioGRID PMID: 29117568,28675297
Reconstituted Complex
BioGRID:111700 BioGRID:106601 ACTL6A BioGRID PMID: 31685992
Positive Genetic
BioGRID:111700 BioGRID:106614 ADA BioGRID PMID: 28319113
Reconstituted Complex
BioGRID:111700 BioGRID:106617 ADAR BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:127907 ADGRF3 BioGRID PMID: 15717329
Affinity Capture-MS
BioGRID:111700 BioGRID:116139 AFG3L2 BioGRID PMID: 30631154
Affinity Capture-Western; Reconstituted Complex
BioGRID:111700 BioGRID:106682 AFP BioGRID PMID: 31811908
Affinity Capture-MS
BioGRID:111700 BioGRID:115987 AHCYL1 BioGRID PMID: 28675297
Reconstituted Complex
BioGRID:111700 BioGRID:114958 AKAP12 BioGRID PMID: 26561776
Affinity Capture-Western; FRET
BioGRID:111700 BioGRID:106710 AKT1 BioGRID PMID: 28205554,20605778
Reconstituted Complex
BioGRID:111700 BioGRID:115486 ALYREF BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:106766 AMHR2 BioGRID PMID: 15717329
Affinity Capture-MS; Reconstituted Complex
BioGRID:111700 BioGRID:127557 AMOT BioGRID PMID: 31685992,21532586
Reconstituted Complex
BioGRID:111700 BioGRID:115665 ANAPC10 BioGRID PMID: 31685992
Affinity Capture-MS; Affinity Capture-Western
BioGRID:111700 BioGRID:118982 ANAPC4 BioGRID PMID: 21241890
Affinity Capture-MS; Affinity Capture-Western
BioGRID:111700 BioGRID:119537 ANAPC5 BioGRID PMID: 21241890
Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
BioGRID:111700 BioGRID:119538 ANAPC7 BioGRID PMID: 31685992,21241890
Two-hybrid
BioGRID:111700 BioGRID:106780 ANG BioGRID PMID: 16169070
Affinity Capture-MS
BioGRID:111700 BioGRID:118888 ANKRD11 BioGRID PMID: 30631154
Two-hybrid
BioGRID:111700 BioGRID:115795 ANP32B BioGRID PMID: 24412244
Reconstituted Complex
BioGRID:111700 BioGRID:123548 ANP32E BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:106799 ANXA2 BioGRID PMID: 26561776
Affinity Capture-MS
BioGRID:111700 BioGRID:106801 ANXA2P2 BioGRID PMID: 32249768
Affinity Capture-MS
BioGRID:111700 BioGRID:106844 APOD BioGRID PMID: 29117568,28675297
Affinity Capture-Western; Reconstituted Complex
BioGRID:111700 BioGRID:106862 AR BioGRID PMID: 15205473
Affinity Capture-MS
BioGRID:111700 BioGRID:122163 ARAP3 BioGRID PMID: 29117568,28675297
Reconstituted Complex
BioGRID:111700 BioGRID:106873 ARF4 BioGRID PMID: 26561776
Affinity Capture-MS
BioGRID:111700 BioGRID:116720 ARHGAP26 BioGRID PMID: 15717329
Negative Genetic
BioGRID:111700 BioGRID:113894 ARID1A BioGRID PMID: 35559673
Affinity Capture-MS
BioGRID:111700 BioGRID:123866 ARMC2 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:119614 ARMCX3 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:106901 ARRB1 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:116170 ASCC3 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:127385 ASPRV1 BioGRID PMID: 28675297
Reconstituted Complex
BioGRID:111700 BioGRID:106987 ATP5F1A BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:106997 ATP5F1C BioGRID PMID: 26561776
Affinity Capture-MS
BioGRID:111700 BioGRID:107028 ATRX BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:231572 Aars BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:225601 Acat1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:225610 Acat2 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:222369 Acly BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:197943 Acta1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:197944 Actb BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:207569 Actr1a BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:216504 Actr3 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:211439 Ahnak BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:198069 Akr1b3 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:198063 Aldh1a1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:204918 Aldh1a7 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:201194 Anxa1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:229475 Arcn1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:198253 Atp5a1 BioGRID PMID: 18307411
Negative Genetic
BioGRID:111700 BioGRID:115919 B3GNT2 BioGRID PMID: 28319085
Positive Genetic
BioGRID:111700 BioGRID:114246 B4GALT3 BioGRID PMID: 28319085
Affinity Capture-MS
BioGRID:111700 BioGRID:114908 BAG2 BioGRID PMID: 32249768
Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
BioGRID:111700 BioGRID:113911 BAP1 BioGRID PMID: 34094668,33155366,15717329
Affinity Capture-MS
BioGRID:111700 BioGRID:121304 BBX BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:114934 BCAR1 BioGRID PMID: 9927060
Affinity Capture-MS
BioGRID:111700 BioGRID:107065 BCKDHA BioGRID PMID: 21532586
Two-hybrid
BioGRID:111700 BioGRID:120961 BEX1 BioGRID PMID: 25640309
Affinity Capture-RNA; Protein-RNA
BioGRID:111700 BioGRID:3196665 BGLT3 BioGRID PMID: 33543443
Affinity Capture-MS
BioGRID:111700 BioGRID:121521 BIRC6 BioGRID PMID: 30631154
Synthetic Growth Defect
BioGRID:111700 BioGRID:108917 BLOC1S1 BioGRID PMID: 24104479
Affinity Capture-Western
BioGRID:111700 BioGRID:107116 BMI1 BioGRID PMID: 19903340
Affinity Capture-MS
BioGRID:111700 BioGRID:116850 BOP1 BioGRID PMID: 32249768
Positive Genetic
BioGRID:111700 BioGRID:107141 BRAF BioGRID PMID: 28319113
Negative Genetic
BioGRID:111700 BioGRID:117036 BRD4 BioGRID PMID: 28319113
Reconstituted Complex
BioGRID:111700 BioGRID:114621 BUB3 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:126002 C2CD4C BioGRID PMID: 30631154
Negative Genetic
BioGRID:111700 BioGRID:107224 CA11 BioGRID PMID: 35559673
Two-hybrid
BioGRID:111700 BioGRID:135670 CACTIN-AS1 BioGRID PMID: 21653829
Reconstituted Complex
BioGRID:111700 BioGRID:107243 CAD BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:107252 CALM1 BioGRID PMID: 26561776
Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
BioGRID:111700 BioGRID:107268 CAMK2G BioGRID PMID: 28636948
Affinity Capture-MS; Negative Genetic
BioGRID:111700 BioGRID:120937 CAND1 BioGRID PMID: 32249768,28319085
Affinity Capture-MS
BioGRID:111700 BioGRID:122431 CAPRIN2 BioGRID PMID: 30631154
Synthetic Growth Defect
BioGRID:111700 BioGRID:122730 CARS2 BioGRID PMID: 24104479
Affinity Capture-MS; Affinity Capture-Western
BioGRID:111700 BioGRID:107291 CASP8 BioGRID PMID: 15717329
Affinity Capture-MS
BioGRID:111700 BioGRID:107297 CAT BioGRID PMID: 29117568
Affinity Capture-Western
BioGRID:111700 BioGRID:107305 CAV1 BioGRID PMID: 12176037
Affinity Capture-Western; Biochemical Activity
BioGRID:111700 BioGRID:107315 CBL BioGRID PMID: 34831026,23118026
Two-hybrid
BioGRID:111700 BioGRID:1527673 CCDC180 BioGRID PMID: 24412244
Reconstituted Complex
BioGRID:111700 BioGRID:121318 CCDC47 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:122854 CCDC7 BioGRID PMID: 30631154
FRET
BioGRID:111700 BioGRID:107334 CCND2 BioGRID PMID: 28205554
Affinity Capture-MS; Affinity Capture-Western
BioGRID:111700 BioGRID:114582 CCNE2 BioGRID PMID: 15717329
Reconstituted Complex
BioGRID:111700 BioGRID:115827 CCT2 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:113054 CCT3 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:115826 CCT4 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:107346 CCT6A BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:115933 CCT8 BioGRID PMID: 31685992
Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
BioGRID:111700 BioGRID:107431 CDC27 BioGRID PMID: 21241890
Synthetic Growth Defect
BioGRID:111700 BioGRID:127125 CDC42EP5 BioGRID PMID: 24104479
Affinity Capture-MS
BioGRID:111700 BioGRID:107436 CDH3 BioGRID PMID: 30631154
Positive Genetic
BioGRID:111700 BioGRID:107454 CDK4 BioGRID PMID: 28319113
Positive Genetic
BioGRID:111700 BioGRID:107463 CDKN2A BioGRID PMID: 28319113
Affinity Capture-MS
BioGRID:111700 BioGRID:107472 CDSN BioGRID PMID: 29117568
Affinity Capture-MS; Affinity Capture-Western
BioGRID:111700 BioGRID:107489 CENPC BioGRID PMID: 17218262,15717329
Affinity Capture-MS
BioGRID:111700 BioGRID:124865 CENPL BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:116641 CEP131 BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:116506 CEP162 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:115193 CEP170 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:122737 CEP97 BioGRID PMID: 31685992
Synthetic Growth Defect
BioGRID:111700 BioGRID:107098 CFB BioGRID PMID: 24104479
Reconstituted Complex
BioGRID:111700 BioGRID:107499 CFL1 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:107533 CHD4 BioGRID PMID: 31685992
Negative Genetic
BioGRID:111700 BioGRID:107536 CHEK1 BioGRID PMID: 28319113
Two-hybrid
BioGRID:111700 BioGRID:107539 CHGB BioGRID PMID: 16169070
Affinity Capture-MS
BioGRID:111700 BioGRID:1147424 CHMP4BP1 BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:117547 CHTOP BioGRID PMID: 32249768
Affinity Capture-Western
BioGRID:111700 BioGRID:107569 CHUK BioGRID PMID: 26787927
Affinity Capture-MS
BioGRID:111700 BioGRID:107573 CIRBP BioGRID PMID: 32249768
Affinity Capture-MS
BioGRID:111700 BioGRID:116167 CKAP4 BioGRID PMID: 29117568
Affinity Capture-MS
BioGRID:111700 BioGRID:116769 CLCC1 BioGRID PMID: 32249768
Affinity Capture-MS
BioGRID:111700 BioGRID:125512 CLNK BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:120993 CMAS BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:125251 CMTM1 BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:113387 CNBP BioGRID PMID: 32249768
Negative Genetic
BioGRID:111700 BioGRID:110912 CNOT4 BioGRID PMID: 35559673
Affinity Capture-MS
BioGRID:111700 BioGRID:125533 CNTROB BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:107709 COPA BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:107710 COPB1 BioGRID PMID: 31685992
Two-hybrid
BioGRID:111700 BioGRID:116176 COPS6 BioGRID PMID: 16169070
Negative Genetic
BioGRID:111700 BioGRID:125940 COX6B2 BioGRID PMID: 35559673
Biochemical Activity
BioGRID:111700 BioGRID:107775 CREB1 BioGRID PMID: 31217297
Affinity Capture-MS
BioGRID:111700 BioGRID:107789 CRKL BioGRID PMID: 15717329
Negative Genetic
BioGRID:111700 BioGRID:107832 CSK BioGRID PMID: 35559673
Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
BioGRID:111700 BioGRID:107836 CSNK1A1 BioGRID PMID: 29593330
Affinity Capture-MS; Biochemical Activity; Reconstituted Complex
BioGRID:111700 BioGRID:107841 CSNK2A1 BioGRID PMID: 31685992,25047839,15717329,12297295
Biochemical Activity; Reconstituted Complex
BioGRID:111700 BioGRID:107842 CSNK2A2 BioGRID PMID: 31685992,12297295
Positive Genetic
BioGRID:111700 BioGRID:107869 CTBP1 BioGRID PMID: 28319085
Affinity Capture-Western
BioGRID:111700 BioGRID:107880 CTNNB1 BioGRID PMID: 20372837
Affinity Capture-Western
BioGRID:111700 BioGRID:114032 CUL1 BioGRID PMID: 32249768
Affinity Capture-MS
BioGRID:111700 BioGRID:114029 CUL4A BioGRID PMID: 30945288
Biochemical Activity
BioGRID:111700 BioGRID:114028 CUL4B BioGRID PMID: 29499938
Two-hybrid
BioGRID:111700 BioGRID:109176 CXCL1 BioGRID PMID: 25640309
Affinity Capture-Western; Two-hybrid
BioGRID:111700 BioGRID:119045 CXXC1 BioGRID PMID: 21653829
Synthetic Growth Defect
BioGRID:111700 BioGRID:108071 CYB5R3 BioGRID PMID: 24104479
Affinity Capture-MS
BioGRID:111700 BioGRID:198468 Cap1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:198471 Capn2 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:198565 Cct3 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:198567 Cct4 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:198568 Cct5 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:198569 Cct6a BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:198571 Cct7 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:198684 Cfl1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:198685 Cfl2 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:212086 Cltc BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:206180 Ctps BioGRID PMID: 18307411
Reconstituted Complex
BioGRID:111700 BioGRID:113587 DAP3 BioGRID PMID: 31685992
Affinity Capture-Western; Reconstituted Complex
BioGRID:111700 BioGRID:107985 DAXX BioGRID PMID: 28497778
Affinity Capture-MS
BioGRID:111700 BioGRID:123157 DBF4B BioGRID PMID: 15717329
Reconstituted Complex
BioGRID:111700 BioGRID:107995 DBN1 BioGRID PMID: 26561776
Affinity Capture-MS
BioGRID:111700 BioGRID:107997 DBT BioGRID PMID: 21532586
Reconstituted Complex
BioGRID:111700 BioGRID:123251 DCAF11 BioGRID PMID: 26561776
Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
BioGRID:111700 BioGRID:117393 DCAF13 BioGRID PMID: 29499938
Reconstituted Complex
BioGRID:111700 BioGRID:108009 DDB1 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:108017 DDOST BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:108019 DDX1 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:114625 DDX21 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:121353 DDX24 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:119375 DDX47 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:122480 DDX50 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:114095 DGKZ BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:108029 DHX15 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:108025 DHX9 BioGRID PMID: 31685992
Affinity Capture-Western; Reconstituted Complex
BioGRID:111700 BioGRID:115667 DLC1 BioGRID PMID: 19482022
Co-fractionation; Reconstituted Complex
BioGRID:111700 BioGRID:108083 DLG1 BioGRID PMID: 11707428,11439092
Affinity Capture-MS
BioGRID:111700 BioGRID:126999 DNAAF8 BioGRID PMID: 33961781
Reconstituted Complex
BioGRID:111700 BioGRID:109534 DNAJA1 BioGRID PMID: 31685992,26561776
Reconstituted Complex
BioGRID:111700 BioGRID:115582 DNAJA2 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:114547 DNAJA3 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:115360 DNAJB6 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:119947 DNAJC10 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:117946 DNAJC2 BioGRID PMID: 32249768
Reconstituted Complex
BioGRID:111700 BioGRID:114340 DPM1 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:110810 DRG1 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:108162 DSG1 BioGRID PMID: 32249768
Reconstituted Complex
BioGRID:111700 BioGRID:108166 DSP BioGRID PMID: 26561776
Affinity Capture-MS
BioGRID:111700 BioGRID:108187 DUT BioGRID PMID: 32249768
Affinity Capture-MS
BioGRID:111700 BioGRID:108189 DVL2 BioGRID PMID: 34299191
Affinity Capture-MS
BioGRID:111700 BioGRID:199084 Ddx3x BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:207975 Dstn BioGRID PMID: 18307411
Affinity Capture-Western
BioGRID:111700 BioGRID:108201 E2F1 BioGRID PMID: 29108454
Affinity Capture-Western
BioGRID:111700 BioGRID:567392 ECSCR BioGRID PMID: 21593423
Negative Genetic
BioGRID:111700 BioGRID:114265 EED BioGRID PMID: 28319085
Affinity Capture-MS
BioGRID:111700 BioGRID:108238 EEF1A2 BioGRID PMID: 15717329
Reconstituted Complex
BioGRID:111700 BioGRID:108258 EEF2 BioGRID PMID: 26561776
Affinity Capture-MS
BioGRID:111700 BioGRID:121953 EEFSEC BioGRID PMID: 30631154
Affinity Capture-Western; Positive Genetic
BioGRID:111700 BioGRID:108276 EGFR BioGRID PMID: 34831026,31741433,26531778
Affinity Capture-Western
BioGRID:111700 BioGRID:108278 EGR1 BioGRID PMID: 21354147
Affinity Capture-Western
BioGRID:111700 BioGRID:111596 EIF2AK2 BioGRID PMID: 20029030
Reconstituted Complex
BioGRID:111700 BioGRID:108292 EIF4E BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:109898 EIF6 BioGRID PMID: 31685992
Affinity Capture-RNA
BioGRID:111700 BioGRID:108309 ELAVL1 BioGRID PMID: 19322201
Negative Genetic
BioGRID:111700 BioGRID:116595 ELL2 BioGRID PMID: 35559673
Affinity Capture-MS
BioGRID:111700 BioGRID:127829 ELOA3P BioGRID PMID: 15717329
Affinity Capture-MS
BioGRID:111700 BioGRID:114090 ELP1 BioGRID PMID: 32249768
Affinity Capture-MS; Reconstituted Complex
BioGRID:111700 BioGRID:108325 EMD BioGRID PMID: 32249768,31685992
Synthetic Growth Defect
BioGRID:111700 BioGRID:128252 EME2 BioGRID PMID: 24104479
Two-hybrid
BioGRID:111700 BioGRID:108324 EML1 BioGRID PMID: 21653829
Synthetic Growth Defect
BioGRID:111700 BioGRID:108340 ENO2 BioGRID PMID: 24104479
FRET
BioGRID:111700 BioGRID:108288 EPHA2 BioGRID PMID: 28205554
Affinity Capture-Western
BioGRID:111700 BioGRID:108361 EPHB1 BioGRID PMID: 23118026
Reconstituted Complex
BioGRID:111700 BioGRID:108372 EPRS1 BioGRID PMID: 31685992
Two-hybrid
BioGRID:111700 BioGRID:108377 ERBB3 BioGRID PMID: 28065597
Reconstituted Complex
BioGRID:111700 BioGRID:108403 ESR1 BioGRID PMID: 15205473
Affinity Capture-MS
BioGRID:111700 BioGRID:108414 ETS1 BioGRID PMID: 21532586
Affinity Capture-MS
BioGRID:111700 BioGRID:115884 EXOC5 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:119220 EXOSC1 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:116977 EXOSC2 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:120007 EXOSC4 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:121243 EXOSC5 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:116658 EXOSC7 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:108440 EYA2 BioGRID PMID: 28675297
Positive Genetic
BioGRID:111700 BioGRID:108446 EZH2 BioGRID PMID: 28319085
Affinity Capture-MS
BioGRID:111700 BioGRID:199385 Eef1a1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:207744 Eef1b2 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:211625 Eef1d BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:211986 Eef1g BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:199387 Eef2 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:199418 Eif4a1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:199451 Eno1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:199507 Esd BioGRID PMID: 18307411
Negative Genetic
BioGRID:111700 BioGRID:123086 FAM106A BioGRID PMID: 35559673
Reconstituted Complex
BioGRID:111700 BioGRID:108487 FARSA BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:115367 FARSB BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:108488 FASN BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:108399 FBL BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:108495 FBN2 BioGRID PMID: 15717329
Co-localization
BioGRID:111700 BioGRID:117625 FBXL5 BioGRID PMID: 30257389
Synthetic Growth Defect
BioGRID:111700 BioGRID:117624 FBXL6 BioGRID PMID: 24104479
Affinity Capture-MS; Affinity Capture-Western
BioGRID:111700 BioGRID:117649 FBXO22 BioGRID PMID: 32249768
Reconstituted Complex
BioGRID:111700 BioGRID:116887 FBXW11 BioGRID PMID: 31685992
Affinity Capture-Western
BioGRID:111700 BioGRID:120581 FBXW7 BioGRID PMID: 23514585
Affinity Capture-MS
BioGRID:111700 BioGRID:108528 FEN1 BioGRID PMID: 32249768
Affinity Capture-MS
BioGRID:111700 BioGRID:108579 FKBP5 BioGRID PMID: 29117568,28675297
Two-hybrid
BioGRID:111700 BioGRID:108605 FLNA BioGRID PMID: 21653829
Affinity Capture-MS; Reconstituted Complex
BioGRID:111700 BioGRID:108606 FLNB BioGRID PMID: 32249768,26561776
Affinity Capture-MS
BioGRID:111700 BioGRID:116686 FNBP1 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:128769 FOXK1 BioGRID PMID: 31685992
Affinity Capture-MS; Affinity Capture-Western
BioGRID:111700 BioGRID:108726 FRK BioGRID PMID: 19345329
Affinity Capture-MS
BioGRID:111700 BioGRID:3188904 FSBP BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:112508 FSCN1 BioGRID PMID: 31298480
Affinity Capture-MS
BioGRID:111700 BioGRID:134873 FSIP2 BioGRID PMID: 30631154
Phenotypic Enhancement
BioGRID:111700 BioGRID:114399 FUBP1 BioGRID PMID: 31553912
Reconstituted Complex
BioGRID:111700 BioGRID:114451 FUBP3 BioGRID PMID: 31685992
Affinity Capture-Western; Reconstituted Complex
BioGRID:111700 BioGRID:119489 FZR1 BioGRID PMID: 24811168,21241890
Affinity Capture-MS
BioGRID:111700 BioGRID:199596 Fasn BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:228662 Flna BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:231475 Fus BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:115237 G3BP2 BioGRID PMID: 15717329
Reconstituted Complex
BioGRID:111700 BioGRID:119102 GEMIN4 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:108943 GFRA2 BioGRID PMID: 15717329
Reconstituted Complex
BioGRID:111700 BioGRID:109032 GNAI1 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:109033 GNAI2 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:121887 GNB4 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:117690 GNL3 BioGRID PMID: 31685992
Affinity Capture-MS; Reconstituted Complex
BioGRID:111700 BioGRID:109079 GPC1 BioGRID PMID: 30631154,26561776
Reconstituted Complex
BioGRID:111700 BioGRID:108530 GPC4 BioGRID PMID: 26561776
Synthetic Growth Defect
BioGRID:111700 BioGRID:109110 GPER1 BioGRID PMID: 24104479
Affinity Capture-MS
BioGRID:111700 BioGRID:118086 GPKOW BioGRID PMID: 32249768
Affinity Capture-Western
BioGRID:111700 BioGRID:109142 GRB2 BioGRID PMID: 31320611
Reconstituted Complex
BioGRID:111700 BioGRID:109201 GSTM2 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:109231 GTF3C2 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:114739 GTF3C3 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:114737 GTF3C5 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:199892 Gdi2 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:588567 Gm16470 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:578322 Gm8129 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:109260 H1-0 BioGRID PMID: 32249768
Reconstituted Complex
BioGRID:111700 BioGRID:113931 H2AC4 BioGRID PMID: 26561776
Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
BioGRID:111700 BioGRID:109268 H2AX BioGRID PMID: 31217297
Reconstituted Complex
BioGRID:111700 BioGRID:109280 HADHA BioGRID PMID: 31685992
Synthetic Growth Defect
BioGRID:111700 BioGRID:123991 HAGHL BioGRID PMID: 24104479
Two-hybrid
BioGRID:111700 BioGRID:109289 HBA1 BioGRID PMID: 16169070
Affinity Capture-MS
BioGRID:111700 BioGRID:109293 HBB BioGRID PMID: 29117568
Affinity Capture-MS
BioGRID:111700 BioGRID:115330 HDAC6 BioGRID PMID: 30631154
Synthetic Growth Defect
BioGRID:111700 BioGRID:121976 HEATR6 BioGRID PMID: 24104479
Synthetic Growth Defect
BioGRID:111700 BioGRID:132759 HES5 BioGRID PMID: 24104479
Synthetic Growth Defect
BioGRID:111700 BioGRID:120682 HES6 BioGRID PMID: 24104479
Reconstituted Complex
BioGRID:111700 BioGRID:109420 HNRNPA1 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:128670 HNRNPA3 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:109423 HNRNPAB BioGRID PMID: 31685992
Affinity Capture-RNA
BioGRID:111700 BioGRID:109432 HNRNPL BioGRID PMID: 28611215
Affinity Capture-MS
BioGRID:111700 BioGRID:109433 HNRNPU BioGRID PMID: 21532586
Reconstituted Complex
BioGRID:111700 BioGRID:116281 HNRNPUL1 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:121926 HPSE2 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:109525 HSD17B1 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:109278 HSD17B10 BioGRID PMID: 31685992
Affinity Capture-MS; Positive Genetic
BioGRID:111700 BioGRID:109552 HSP90AA1 BioGRID PMID: 28319113,21532586
Affinity Capture-MS; Positive Genetic; Reconstituted Complex
BioGRID:111700 BioGRID:109558 HSP90AB1 BioGRID PMID: 28319085,26561776,21532586
Reconstituted Complex
BioGRID:111700 BioGRID:113036 HSP90B1 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:109535 HSPA1A BioGRID PMID: 21532586
Affinity Capture-MS
BioGRID:111700 BioGRID:109537 HSPA1L BioGRID PMID: 21532586
Affinity Capture-MS
BioGRID:111700 BioGRID:109538 HSPA2 BioGRID PMID: 21532586
Reconstituted Complex
BioGRID:111700 BioGRID:109540 HSPA4 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:116500 HSPA4L BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:109542 HSPA6 BioGRID PMID: 21532586
Affinity Capture-MS; Reconstituted Complex
BioGRID:111700 BioGRID:109544 HSPA8 BioGRID PMID: 26561776,21532586
Reconstituted Complex
BioGRID:111700 BioGRID:117168 HSPBP1 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:109561 HSPD1 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:116022 HSPH1 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:207301 Hnrnpa2b1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:230827 Hnrnpa3 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:221126 Hnrnpf BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:200359 Hnrnpk BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:200360 Hnrnpl BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:206185 Hnrnpu BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:200455 Hsp90aa1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:200454 Hsp90ab1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:204301 Hsp90b1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:200456 Hspa4 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:200078 Hspa5 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:200428 Hspa8 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:200451 Hspd1 BioGRID PMID: 18307411
Affinity Capture-MS; Affinity Capture-Western
BioGRID:111700 BioGRID:109642 IDE BioGRID PMID: 30649986,28675297
Synthetic Growth Defect
BioGRID:111700 BioGRID:122082 IFIH1 BioGRID PMID: 24104479
Negative Genetic
BioGRID:111700 BioGRID:109701 IGF1R BioGRID PMID: 28319085
Negative Genetic
BioGRID:111700 BioGRID:115886 IGF2BP1 BioGRID PMID: 28319085
Positive Genetic
BioGRID:111700 BioGRID:109703 IGF2R BioGRID PMID: 28319085
Affinity Capture-MS
BioGRID:111700 BioGRID:130074 IGSF10 BioGRID PMID: 30631154
Two-hybrid
BioGRID:111700 BioGRID:116199 IL24 BioGRID PMID: 25640309
Reconstituted Complex
BioGRID:111700 BioGRID:109821 ILF2 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:109822 ILF3 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:123742 INHBE BioGRID PMID: 15717329
Biochemical Activity
BioGRID:111700 BioGRID:109842 INS BioGRID PMID: 11439092
Affinity Capture-MS
BioGRID:111700 BioGRID:122828 IPO4 BioGRID PMID: 29117568,28675297
Reconstituted Complex
BioGRID:111700 BioGRID:110041 IPO5 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:115782 IPO7 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:132986 IQCF2 BioGRID PMID: 30631154
Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
BioGRID:111700 BioGRID:114048 IRS4 BioGRID PMID: 31685992,15717329
Affinity Capture-MS
BioGRID:111700 BioGRID:109864 ITGA6 BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:109901 ITGB7 BioGRID PMID: 30631154
Affinity Capture-Western
BioGRID:111700 BioGRID:109915 ITPR3 BioGRID PMID: 28614300
Reconstituted Complex
BioGRID:111700 BioGRID:112622 ITPRID2 BioGRID PMID: 26561776
Affinity Capture-MS
BioGRID:111700 BioGRID:200510 Idh1 BioGRID PMID: 18307411
Reconstituted Complex
BioGRID:111700 BioGRID:109931 JUP BioGRID PMID: 26561776
Affinity Capture-Western
BioGRID:111700 BioGRID:114375 KAT2B BioGRID PMID: 16829519
Reconstituted Complex
BioGRID:111700 BioGRID:120833 KBTBD4 BioGRID PMID: 26561776
Affinity Capture-MS
BioGRID:111700 BioGRID:114086 KCNAB2 BioGRID PMID: 32249768
Negative Genetic
BioGRID:111700 BioGRID:116145 KDELR1 BioGRID PMID: 35559673
Reconstituted Complex
BioGRID:111700 BioGRID:116667 KDM1A BioGRID PMID: 31685992
Positive Genetic
BioGRID:111700 BioGRID:113246 KDM6A BioGRID PMID: 28319113
Negative Genetic
BioGRID:111700 BioGRID:114139 KHSRP BioGRID PMID: 28319085
Affinity Capture-MS
BioGRID:111700 BioGRID:110030 KIF11 BioGRID PMID: 30631154
Affinity Capture-Western
BioGRID:111700 BioGRID:107153 KLF5 BioGRID PMID: 35780838
Affinity Capture-Western
BioGRID:111700 BioGRID:110443 KMT2A BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:110035 KPNB1 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:110059 KRT14 BioGRID PMID: 15717329
Affinity Capture-MS
BioGRID:111700 BioGRID:110048 KRT3 BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:133686 KRT39 BioGRID PMID: 30631154
Biochemical Activity
BioGRID:111700 BioGRID:114563 LATS1 BioGRID PMID: 22641346
Affinity Capture-MS
BioGRID:111700 BioGRID:110131 LDHA BioGRID PMID: 32249768
Affinity Capture-MS; Reconstituted Complex
BioGRID:111700 BioGRID:110137 LDHB BioGRID PMID: 32249768,26561776
Reconstituted Complex
BioGRID:111700 BioGRID:110147 LGALS1 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:119559 LIMA1 BioGRID PMID: 26561776
Protein-RNA
BioGRID:111700 BioGRID:124305 LINC00839 BioGRID PMID: 30631154
Affinity Capture-RNA; Protein-RNA
BioGRID:111700 BioGRID:3193082 LINC01198 BioGRID PMID: 31469661
Affinity Capture-RNA; Protein-RNA
BioGRID:111700 BioGRID:3192300 LINC02023 BioGRID PMID: 30849479
Synthetic Growth Defect
BioGRID:111700 BioGRID:110181 LLGL2 BioGRID PMID: 24104479
Affinity Capture-MS
BioGRID:111700 BioGRID:110186 LMNA BioGRID PMID: 29117568
Reconstituted Complex
BioGRID:111700 BioGRID:110187 LMNB1 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:115432 LRPPRC BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:124379 LTV1 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:113574 LUZP1 BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:121406 LYRM1 BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:201127 Ldha BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:201142 Lgals1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:201143 Lgals3 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:201191 Lox BioGRID PMID: 18307411
Reconstituted Complex
BioGRID:111700 BioGRID:116121 MAGED2 BioGRID PMID: 31685992
Affinity Capture-Western; Reconstituted Complex
BioGRID:111700 BioGRID:115197 MAGI2 BioGRID PMID: 11707428,10760291
Affinity Capture-Western; Reconstituted Complex; Two-hybrid
BioGRID:111700 BioGRID:129277 MAGI3 BioGRID PMID: 10748157
Positive Genetic
BioGRID:111700 BioGRID:110294 MAN1A1 BioGRID PMID: 28319085
Negative Genetic
BioGRID:111700 BioGRID:116414 MAN1B1 BioGRID PMID: 28319085
FRET
BioGRID:111700 BioGRID:111592 MAP2K3 BioGRID PMID: 28205554
Affinity Capture-MS
BioGRID:111700 BioGRID:111594 MAP2K6 BioGRID PMID: 15717329
Affinity Capture-MS
BioGRID:111700 BioGRID:111580 MAPK1 BioGRID PMID: 32249768
Affinity Capture-MS
BioGRID:111700 BioGRID:110257 MARCKS BioGRID PMID: 32249768
Co-crystal Structure; Reconstituted Complex
BioGRID:111700 BioGRID:116756 MAST2 BioGRID PMID: 22894835
Reconstituted Complex
BioGRID:111700 BioGRID:115126 MATR3 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:121249 MCCC1 BioGRID PMID: 21532586
Affinity Capture-MS
BioGRID:111700 BioGRID:122050 MCCC2 BioGRID PMID: 21532586
Reconstituted Complex
BioGRID:111700 BioGRID:110339 MCM2 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:110340 MCM3 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:110342 MCM5 BioGRID PMID: 31685992
Affinity Capture-MS; Reconstituted Complex
BioGRID:111700 BioGRID:110344 MCM7 BioGRID PMID: 32249768,31685992
Affinity Capture-Western; Far Western; Reconstituted Complex
BioGRID:111700 BioGRID:115710 MCRS1 BioGRID PMID: 15659546
Affinity Capture-Western; Reconstituted Complex
BioGRID:111700 BioGRID:115014 MDC1 BioGRID PMID: 31217297
Reconstituted Complex
BioGRID:111700 BioGRID:116804 MDN1 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:115293 MED12 BioGRID PMID: 15717329
Positive Genetic
BioGRID:111700 BioGRID:110391 MET BioGRID PMID: 28319113
Affinity Capture-MS
BioGRID:111700 BioGRID:122519 METTL16 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:124050 METTL26 BioGRID PMID: 26561776
Affinity Capture-MS; Biochemical Activity
BioGRID:111700 BioGRID:119471 MEX3C BioGRID PMID: 30741721,30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:134376 MEX3D BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:110434 MKI67 BioGRID PMID: 31685992
Affinity Capture-Western; Co-localization; Reconstituted Complex
BioGRID:111700 BioGRID:110455 MME BioGRID PMID: 20957047,14749127
Positive Genetic
BioGRID:111700 BioGRID:113599 MOGS BioGRID PMID: 28319085
Reconstituted Complex; Two-hybrid
BioGRID:111700 BioGRID:116776 MPRIP BioGRID PMID: 26561776,21653829
Affinity Capture-MS
BioGRID:111700 BioGRID:122369 MRPL11 BioGRID PMID: 32249768
Reconstituted Complex
BioGRID:111700 BioGRID:121269 MRPS22 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:119657 MRPS23 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:116731 MRPS27 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:118784 MRPS28 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:119271 MRPS7 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:122360 MRPS9 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:109211 MSH6 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:110622 MTHFD1 BioGRID PMID: 32249768
Reconstituted Complex
BioGRID:111700 BioGRID:116011 MTHFD2 BioGRID PMID: 26561776
Negative Genetic
BioGRID:111700 BioGRID:108757 MTOR BioGRID PMID: 28319113
Negative Genetic
BioGRID:111700 BioGRID:125018 MVB12A BioGRID PMID: 35559673
Affinity Capture-Western; Reconstituted Complex; Two-hybrid
BioGRID:111700 BioGRID:115286 MVP BioGRID PMID: 12177006
Synthetic Growth Defect
BioGRID:111700 BioGRID:110259 MXD1 BioGRID PMID: 24104479
Reconstituted Complex
BioGRID:111700 BioGRID:115770 MYBBP1A BioGRID PMID: 31685992
FRET
BioGRID:111700 BioGRID:110694 MYC BioGRID PMID: 28205554
Reconstituted Complex
BioGRID:111700 BioGRID:110713 MYH10 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:115871 MYL12A BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:110567 MYO1B BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:110725 MYO1C BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:110726 MYO1D BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:117715 MYOF BioGRID PMID: 26561776
Affinity Capture-MS
BioGRID:111700 BioGRID:201584 Map1b BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:211799 Mtap BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:201650 Myh9 BioGRID PMID: 18307411
Reconstituted Complex
BioGRID:111700 BioGRID:110748 NACA BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:110766 NCBP1 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:575724 NCF1 BioGRID PMID: 26561776
Affinity Capture-Western
BioGRID:111700 BioGRID:113841 NCOA3 BioGRID PMID: 23514585
Affinity Capture-MS
BioGRID:111700 BioGRID:114974 NCOR2 BioGRID PMID: 30631154
Affinity Capture-Western; PCA
BioGRID:111700 BioGRID:123296 NDFIP1 BioGRID PMID: 24798731,22213801,20534535
Affinity Capture-Western
BioGRID:111700 BioGRID:120074 NDFIP2 BioGRID PMID: 20534535
Negative Genetic
BioGRID:111700 BioGRID:110797 NDUFC1 BioGRID PMID: 35559673
Affinity Capture-MS
BioGRID:111700 BioGRID:125728 NEDD1 BioGRID PMID: 30631154
Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
BioGRID:111700 BioGRID:110811 NEDD4 BioGRID PMID: 33712741,31578285,31469661,30594392,29593330,28437168,27295432,25547115,25047839,24141722,24063548,21986318,19345329,18498243,18307411
Positive Genetic
BioGRID:111700 BioGRID:110836 NF1 BioGRID PMID: 28319113
Negative Genetic
BioGRID:111700 BioGRID:118095 NFU1 BioGRID PMID: 35559673
Reconstituted Complex
BioGRID:111700 BioGRID:121798 NGB BioGRID PMID: 23904011
Affinity Capture-MS; Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex; Two-hybrid
BioGRID:111700 BioGRID:114769 NHERF1 BioGRID PMID: 30631154,26531778,23118026,21990315,21804599,16456542
Reconstituted Complex
BioGRID:111700 BioGRID:1172218 NHERF1 BioGRID PMID: 21990315
Affinity Capture-Western; Reconstituted Complex
BioGRID:111700 BioGRID:114754 NHERF2 BioGRID PMID: 16456542
Affinity Capture-MS; Reconstituted Complex
BioGRID:111700 BioGRID:110894 NME1 BioGRID PMID: 32249768,26561776
Affinity Capture-MS
BioGRID:111700 BioGRID:117586 NOC2L BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:115783 NOP56 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:119631 NOP58 BioGRID PMID: 31685992
Synthetic Growth Defect
BioGRID:111700 BioGRID:110913 NOTCH1 BioGRID PMID: 24104479
Reconstituted Complex
BioGRID:111700 BioGRID:115640 NPM3 BioGRID PMID: 31685992
Positive Genetic
BioGRID:111700 BioGRID:113796 NPRL3 BioGRID PMID: 28319085
Affinity Capture-MS
BioGRID:111700 BioGRID:110953 NRCAM BioGRID PMID: 30631154
Affinity Capture-Western
BioGRID:111700 BioGRID:113306 NSD2 BioGRID PMID: 31217297
Affinity Capture-Western; Reconstituted Complex
BioGRID:111700 BioGRID:114202 NUMB BioGRID PMID: 28437168
Affinity Capture-MS
BioGRID:111700 BioGRID:207325 Nap1l1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:213922 Nars BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:201706 Ncl BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:201723 Nedd4 BioGRID PMID: 18307411
Affinity Capture-Western
BioGRID:111700 BioGRID:211159 Nherf2 BioGRID PMID: 16456542
Affinity Capture-MS
BioGRID:111700 BioGRID:201823 Npm1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:110996 OAT BioGRID PMID: 32249768
Synthetic Growth Defect
BioGRID:111700 BioGRID:111032 OPRL1 BioGRID PMID: 24104479
Synthetic Growth Defect
BioGRID:111700 BioGRID:117263 OSBP2 BioGRID PMID: 24104479
Two-hybrid
BioGRID:111700 BioGRID:118985 OSGIN1 BioGRID PMID: 25640309
Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
BioGRID:111700 BioGRID:116856 OTUD3 BioGRID PMID: 33543443,26280536
Affinity Capture-Western
BioGRID:111700 BioGRID:120738 OTUD5 BioGRID PMID: 35765958
Affinity Capture-MS
BioGRID:111700 BioGRID:211895 Oxct1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:111071 P2RY11 BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:115855 P3H4 BioGRID PMID: 15717329
Negative Genetic
BioGRID:111700 BioGRID:124145 PARD6B BioGRID PMID: 35559673
Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
BioGRID:111700 BioGRID:116446 PARK7 BioGRID PMID: 31891690,30631154,21426932,19885556
Affinity Capture-Western; Biochemical Activity
BioGRID:111700 BioGRID:120971 PBK BioGRID PMID: 24012691
Reconstituted Complex
BioGRID:111700 BioGRID:120490 PBRM1 BioGRID PMID: 31685992
Synthetic Growth Defect
BioGRID:111700 BioGRID:111123 PBX3 BioGRID PMID: 24104479
Affinity Capture-MS
BioGRID:111700 BioGRID:111124 PC BioGRID PMID: 21532586
Affinity Capture-MS
BioGRID:111700 BioGRID:111128 PCCA BioGRID PMID: 21532586
Affinity Capture-MS
BioGRID:111700 BioGRID:111129 PCCB BioGRID PMID: 21532586
Affinity Capture-MS
BioGRID:111700 BioGRID:121046 PCDHGA10 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:111142 PCNA BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:111182 PDGFRA BioGRID PMID: 15717329
Affinity Capture-Western; Biochemical Activity; Co-localization; Reconstituted Complex
BioGRID:111700 BioGRID:111185 PDGFRB BioGRID PMID: 25241761,14718524
Affinity Capture-MS
BioGRID:111700 BioGRID:111186 PDHA1 BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:129119 PDZD9 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:119818 PELO BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:117973 PELP1 BioGRID PMID: 31685992
Affinity Capture-Western
BioGRID:111700 BioGRID:111237 PFN1 BioGRID PMID: 26787927
Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
BioGRID:111700 BioGRID:111251 PGK1 BioGRID PMID: 32249768,31492635
Reconstituted Complex
BioGRID:111700 BioGRID:111264 PHB1 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:116459 PHB2 BioGRID PMID: 31685992
Affinity Capture-Western; Two-hybrid
BioGRID:111700 BioGRID:114849 PICK1 BioGRID PMID: 21653829
Negative Genetic
BioGRID:111700 BioGRID:111301 PIGH BioGRID PMID: 35559673
Synthetic Growth Defect
BioGRID:111700 BioGRID:117100 PIGN BioGRID PMID: 24104479
Affinity Capture-Western; FRET
BioGRID:111700 BioGRID:111313 PIK3R1 BioGRID PMID: 34831026,20212113
Affinity Capture-Western; Biochemical Activity
BioGRID:111700 BioGRID:111314 PIK3R2 BioGRID PMID: 20515662
Affinity Capture-MS
BioGRID:111700 BioGRID:122376 PINK1 BioGRID PMID: 15717329
Reconstituted Complex
BioGRID:111700 BioGRID:111332 PKM BioGRID PMID: 26561776
Synthetic Growth Defect
BioGRID:111700 BioGRID:114544 PKMYT1 BioGRID PMID: 24104479
Affinity Capture-MS
BioGRID:111700 BioGRID:111572 PKN2 BioGRID PMID: 15717329
Reconstituted Complex
BioGRID:111700 BioGRID:111355 PLEC BioGRID PMID: 26561776
Proximity Label-MS
BioGRID:111700 BioGRID:121880 PLEKHA1 BioGRID PMID: 27880917
Affinity Capture-Western; Biochemical Activity
BioGRID:111700 BioGRID:111362 PLK1 BioGRID PMID: 25047839
Synthetic Growth Defect
BioGRID:111700 BioGRID:114171 PLPP3 BioGRID PMID: 24104479
Affinity Capture-MS
BioGRID:111700 BioGRID:123048 POF1B BioGRID PMID: 29117568
Reconstituted Complex
BioGRID:111700 BioGRID:117531 POLDIP2 BioGRID PMID: 31685992,26561776
Synthetic Growth Defect
BioGRID:111700 BioGRID:118168 POLM BioGRID PMID: 24104479
Reconstituted Complex
BioGRID:111700 BioGRID:117396 POLR1A BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:111426 POLR2A BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:111427 POLR2B BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:111433 POLR2H BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:116140 POP1 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:111488 PPL BioGRID PMID: 26561776
Affinity Capture-MS
BioGRID:111700 BioGRID:111491 PPM1G BioGRID PMID: 28675297
Affinity Capture-Western
BioGRID:111700 BioGRID:111493 PPP1CA BioGRID PMID: 17274640
Affinity Capture-MS
BioGRID:111700 BioGRID:111506 PPP1R10 BioGRID PMID: 21532586
Reconstituted Complex
BioGRID:111700 BioGRID:111507 PPP2CA BioGRID PMID: 31685992
Affinity Capture-Western
BioGRID:111700 BioGRID:111522 PPP3CA BioGRID PMID: 20605778
Affinity Capture-MS
BioGRID:111700 BioGRID:111528 PPP5C BioGRID PMID: 28675297
Reconstituted Complex
BioGRID:111700 BioGRID:111089 PRDX1 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:116136 PRDX3 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:111577 PRKDC BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:111105 PRKN BioGRID PMID: 35256949,30631154
Reconstituted Complex
BioGRID:111700 BioGRID:118151 PRPF19 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:115842 PRPF8 BioGRID PMID: 31685992
Synthetic Growth Defect
BioGRID:111700 BioGRID:111663 PSMB2 BioGRID PMID: 24104479
Affinity Capture-MS
BioGRID:111700 BioGRID:111681 PSMD2 BioGRID PMID: 32249768
Reconstituted Complex
BioGRID:111700 BioGRID:111682 PSMD3 BioGRID PMID: 31685992
Affinity Capture-Western; Co-localization; Reconstituted Complex
BioGRID:111700 BioGRID:111683 PSMD4 BioGRID PMID: 30673593
Reconstituted Complex
BioGRID:111700 BioGRID:111685 PSMD7 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:115135 PTDSS1 BioGRID PMID: 31685992
Affinity Capture-MS; Affinity Capture-Western
BioGRID:111700 BioGRID:111700 PTEN BioGRID PMID: 30631154,14976311
Affinity Capture-Western; Biochemical Activity; Co-localization; Reconstituted Complex
BioGRID:111700 BioGRID:111719 PTK2 BioGRID PMID: 23397142,15717329,11857088,10400703,9927060
Affinity Capture-MS
BioGRID:111700 BioGRID:108480 PTK2B BioGRID PMID: 15717329
Two-hybrid
BioGRID:111700 BioGRID:111721 PTK7 BioGRID PMID: 28065597
Affinity Capture-Western
BioGRID:111700 BioGRID:111516 PTPA BioGRID PMID: 15717329
Affinity Capture-MS; Proximity Label-MS
BioGRID:111700 BioGRID:111747 PTPN13 BioGRID PMID: 30631154,27880917
Affinity Capture-MS
BioGRID:111700 BioGRID:111748 PTPN14 BioGRID PMID: 15717329
Reconstituted Complex
BioGRID:111700 BioGRID:111772 PURA BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:111773 PURB BioGRID PMID: 32249768
Affinity Capture-Western; Co-localization
BioGRID:111700 BioGRID:111787 PXN BioGRID PMID: 23397142,11857088
Affinity Capture-MS
BioGRID:111700 BioGRID:204835 Pcbp1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:202043 Pcbp2 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:202049 Pcna BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:202126 Pfn1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:202133 Pgk1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:202191 Pkm BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:234487 Ppia BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:202427 Psmc2 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:202428 Psmc3 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:204845 Psmc4 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:211864 Psmd12 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:212566 Puf60 BioGRID PMID: 18307411
Reconstituted Complex
BioGRID:111700 BioGRID:120171 QPCTL BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:117035 QPRT BioGRID PMID: 32249768
Affinity Capture-MS
BioGRID:111700 BioGRID:123897 QRFPR BioGRID PMID: 15717329
Positive Genetic
BioGRID:111700 BioGRID:123619 RAB1B BioGRID PMID: 28319085
Negative Genetic
BioGRID:111700 BioGRID:111816 RAB5C BioGRID PMID: 28319085
Affinity Capture-MS
BioGRID:111700 BioGRID:113624 RAB7A BioGRID PMID: 28675297
Reconstituted Complex
BioGRID:111700 BioGRID:111822 RAD21 BioGRID PMID: 31685992
Affinity Capture-Western
BioGRID:111700 BioGRID:111825 RAD51 BioGRID PMID: 31320611
Negative Genetic
BioGRID:111700 BioGRID:114018 RAD54L BioGRID PMID: 35559673
Affinity Capture-MS
BioGRID:111700 BioGRID:111835 RALB BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:115557 RAMP2 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:111839 RANBP2 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:111840 RANGAP1 BioGRID PMID: 31685992
Synthetic Growth Defect
BioGRID:111700 BioGRID:115115 RASSF2 BioGRID PMID: 24104479
Reconstituted Complex
BioGRID:111700 BioGRID:111864 RBBP5 BioGRID PMID: 31685992
Affinity Capture-Western
BioGRID:111700 BioGRID:115862 RBCK1 BioGRID PMID: 35174471
Reconstituted Complex
BioGRID:111700 BioGRID:111871 RBM4 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:121001 RCC2 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:111887 RCN1 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:111915 RFC3 BioGRID PMID: 31685992
Affinity Capture-MS; Reconstituted Complex
BioGRID:111700 BioGRID:111916 RFC4 BioGRID PMID: 32249768,31685992
Reconstituted Complex
BioGRID:111700 BioGRID:111917 RFC5 BioGRID PMID: 31685992
Synthetic Growth Defect
BioGRID:111700 BioGRID:116792 RFTN1 BioGRID PMID: 24104479
Affinity Capture-Western
BioGRID:111700 BioGRID:106880 RHOA BioGRID PMID: 22720799
Reconstituted Complex
BioGRID:111700 BioGRID:111947 RING1 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:123743 RIOK1 BioGRID PMID: 30631154
Affinity Capture-Western
BioGRID:111700 BioGRID:120790 RNF126 BioGRID PMID: 33664240
Affinity Capture-Western
BioGRID:111700 BioGRID:123598 RNF146 BioGRID PMID: 25547115
Affinity Capture-MS
BioGRID:111700 BioGRID:112037 RPA1 BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:123917 RPF2 BioGRID PMID: 32249768
Reconstituted Complex
BioGRID:111700 BioGRID:112054 RPL10 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:110813 RPL10A BioGRID PMID: 31685992,26561776
Affinity Capture-MS; Reconstituted Complex
BioGRID:111700 BioGRID:112056 RPL12 BioGRID PMID: 32249768,31685992,26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112057 RPL13 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:117068 RPL13A BioGRID PMID: 26561776
Affinity Capture-MS; Reconstituted Complex
BioGRID:111700 BioGRID:114507 RPL14 BioGRID PMID: 31685992,26561776,15717329
Reconstituted Complex
BioGRID:111700 BioGRID:112059 RPL17 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:112062 RPL18A BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:112064 RPL21 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:112066 RPL22 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:128356 RPL22L1 BioGRID PMID: 31685992,26561776
Reconstituted Complex
BioGRID:111700 BioGRID:114752 RPL23 BioGRID PMID: 31685992,26561776
Affinity Capture-MS; Reconstituted Complex
BioGRID:111700 BioGRID:112067 RPL23A BioGRID PMID: 32249768,31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:112073 RPL26 BioGRID PMID: 32249768
Reconstituted Complex
BioGRID:111700 BioGRID:112074 RPL27 BioGRID PMID: 31685992,26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112076 RPL27A BioGRID PMID: 31685992,26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112077 RPL28 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:112075 RPL30 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:112079 RPL31 BioGRID PMID: 31685992,26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112080 RPL32 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:112083 RPL34 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:117388 RPL36 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:112088 RPL38 BioGRID PMID: 31685992,26561776
Affinity Capture-MS
BioGRID:111700 BioGRID:112045 RPL5 BioGRID PMID: 32249768
Affinity Capture-MS
BioGRID:111700 BioGRID:112048 RPL6 BioGRID PMID: 32249768
Affinity Capture-MS; Reconstituted Complex
BioGRID:111700 BioGRID:112049 RPL7 BioGRID PMID: 32249768,26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112094 RPLP0 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112096 RPLP2 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112100 RPN2 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:115807 RPP30 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:115808 RPP38 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:116013 RPP40 BioGRID PMID: 31685992
Negative Genetic
BioGRID:111700 BioGRID:121820 RPRD1B BioGRID PMID: 35559673
Affinity Capture-MS; Reconstituted Complex
BioGRID:111700 BioGRID:112119 RPS11 BioGRID PMID: 32249768,31685992
Reconstituted Complex
BioGRID:111700 BioGRID:112121 RPS13 BioGRID PMID: 31685992,26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112123 RPS15 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:112124 RPS15A BioGRID PMID: 31685992,26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112132 RPS17 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112101 RPS2 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112138 RPS20 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112142 RPS23 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:112144 RPS25 BioGRID PMID: 31685992,26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112145 RPS26 BioGRID PMID: 31685992,26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112146 RPS27 BioGRID PMID: 31685992,26561776
Affinity Capture-MS; Reconstituted Complex
BioGRID:111700 BioGRID:112147 RPS27A BioGRID PMID: 30631154,26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112102 RPS3 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112105 RPS4X BioGRID PMID: 31685992,26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112107 RPS5 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:112108 RPS6 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112117 RPS9 BioGRID PMID: 31685992,26561776
Affinity Capture-MS
BioGRID:111700 BioGRID:121582 RPTOR BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:125221 RPUSD1 BioGRID PMID: 33961781
Reconstituted Complex
BioGRID:111700 BioGRID:117587 RSL1D1 BioGRID PMID: 31685992
Two-hybrid
BioGRID:111700 BioGRID:116997 RYBP BioGRID PMID: 21653829
Affinity Capture-MS
BioGRID:111700 BioGRID:112175 RYR3 BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:199978 Rack1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:211883 Rpl11 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:202968 Rpl18 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:212608 Rpl22l1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:211121 Rpl23 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:205174 Rpl3 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:785975 Rpl31-ps9 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:198181 Rplp0 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:207787 Rplp1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:203005 Rps17 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:205106 Rps3 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:203011 Rps4x BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:203016 Rps7 BioGRID PMID: 18307411
Reconstituted Complex
BioGRID:111700 BioGRID:112187 S100A8 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112188 S100A9 BioGRID PMID: 26561776
Positive Genetic
BioGRID:111700 BioGRID:121186 SAR1A BioGRID PMID: 28319085
Affinity Capture-MS
BioGRID:111700 BioGRID:131933 SBSN BioGRID PMID: 29117568
Affinity Capture-MS
BioGRID:111700 BioGRID:112240 SCN10A BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:120810 SCYL2 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:112284 SDC1 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112286 SDC4 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112287 SDCBP BioGRID PMID: 26561776
Negative Genetic
BioGRID:111700 BioGRID:115696 SEC24B BioGRID PMID: 28319085
Positive Genetic
BioGRID:111700 BioGRID:114991 SEC24C BioGRID PMID: 28319085
Reconstituted Complex
BioGRID:111700 BioGRID:118968 SEC61A1 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:112769 SERPINA7 BioGRID PMID: 32249768
Negative Genetic
BioGRID:111700 BioGRID:111287 SERPINB6 BioGRID PMID: 35559673
Reconstituted Complex
BioGRID:111700 BioGRID:112316 SET BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:116699 SETX BioGRID PMID: 26561776
Affinity Capture-MS
BioGRID:111700 BioGRID:119553 SFMBT1 BioGRID PMID: 30631154
Affinity Capture-Western
BioGRID:111700 BioGRID:123608 SHARPIN BioGRID PMID: 25152374,20458142
Affinity Capture-MS
BioGRID:111700 BioGRID:121665 SHROOM3 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:117439 SIN3A BioGRID PMID: 31685992
Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
BioGRID:111700 BioGRID:116981 SIRT4 BioGRID PMID: 30649986
Affinity Capture-Western; Reconstituted Complex
BioGRID:111700 BioGRID:112391 SKP1 BioGRID PMID: 32249768,26561776
Affinity Capture-MS
BioGRID:111700 BioGRID:112447 SLC12A2 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:112464 SLC25A1 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:115467 SLC25A13 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:111269 SLC25A3 BioGRID PMID: 31685992,26561776
Reconstituted Complex
BioGRID:111700 BioGRID:106789 SLC25A5 BioGRID PMID: 26561776
Synthetic Growth Defect
BioGRID:111700 BioGRID:106790 SLC25A6 BioGRID PMID: 24104479
Synthetic Growth Defect
BioGRID:111700 BioGRID:128503 SLC36A1 BioGRID PMID: 24104479
Negative Genetic; Reconstituted Complex
BioGRID:111700 BioGRID:112481 SMARCA4 BioGRID PMID: 35559673,31685992
Reconstituted Complex
BioGRID:111700 BioGRID:114045 SMARCA5 BioGRID PMID: 31685992
Negative Genetic
BioGRID:111700 BioGRID:112482 SMARCB1 BioGRID PMID: 35559673
Reconstituted Complex
BioGRID:111700 BioGRID:115841 SMC2 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:115362 SMC4 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:116929 SMCHD1 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:112416 SMTN BioGRID PMID: 15717329
Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
BioGRID:111700 BioGRID:121411 SMURF1 BioGRID PMID: 32737433
Biochemical Activity
BioGRID:111700 BioGRID:112499 SNAI1 BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:117471 SNED1 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:116661 SNRNP200 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:112510 SNRPA BioGRID PMID: 32249768
Reconstituted Complex
BioGRID:111700 BioGRID:112511 SNRPA1 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:112513 SNRPB2 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:112516 SNRPD1 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:112528 SNTB2 BioGRID PMID: 26561776
Affinity Capture-MS; Affinity Capture-Western; Protein-peptide; Reconstituted Complex
BioGRID:111700 BioGRID:123546 SNX27 BioGRID PMID: 32249768,30631154,29117568,28675297
Affinity Capture-MS; Synthetic Growth Defect
BioGRID:111700 BioGRID:114203 SOCS1 BioGRID PMID: 29991678,24104479
Negative Genetic
BioGRID:111700 BioGRID:112534 SON BioGRID PMID: 35559673
Affinity Capture-MS
BioGRID:111700 BioGRID:126329 SPATA18 BioGRID PMID: 30631154
Affinity Capture-Western
BioGRID:111700 BioGRID:113993 SPOP BioGRID PMID: 32297747,27622336
Affinity Capture-MS
BioGRID:111700 BioGRID:112586 SPTA1 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:112587 SPTAN1 BioGRID PMID: 26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112589 SPTBN1 BioGRID PMID: 26561776
Affinity Capture-MS
BioGRID:111700 BioGRID:121583 SRGAP1 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:112605 SRP14 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:112330 SRSF7 BioGRID PMID: 32249768
Reconstituted Complex
BioGRID:111700 BioGRID:112619 SSB BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:112626 SSR4 BioGRID PMID: 31685992,26561776
Reconstituted Complex
BioGRID:111700 BioGRID:112627 SSRP1 BioGRID PMID: 31685992
Synthetic Growth Defect
BioGRID:111700 BioGRID:130764 ST8SIA6 BioGRID PMID: 24104479
Reconstituted Complex
BioGRID:111700 BioGRID:115958 STAG2 BioGRID PMID: 31685992
Negative Genetic
BioGRID:111700 BioGRID:115863 STAMBP BioGRID PMID: 35559673
Affinity Capture-MS
BioGRID:111700 BioGRID:116162 STIP1 BioGRID PMID: 28675297,21532586
Affinity Capture-Western; Biochemical Activity; Co-localization; Two-hybrid
BioGRID:111700 BioGRID:112670 STK11 BioGRID PMID: 15987703
Affinity Capture-MS
BioGRID:111700 BioGRID:118032 STK36 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:116342 STRAP BioGRID PMID: 31685992
Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
BioGRID:111700 BioGRID:115563 STUB1 BioGRID PMID: 34589606,31811908,26280536,22427670
Reconstituted Complex
BioGRID:111700 BioGRID:122174 SUDS3 BioGRID PMID: 31685992
Affinity Capture-Western
BioGRID:111700 BioGRID:119676 SUFU BioGRID PMID: 34021128
Affinity Capture-MS; Reconstituted Complex
BioGRID:111700 BioGRID:115449 SUGP2 BioGRID PMID: 32249768,31685992
Synthetic Growth Defect
BioGRID:111700 BioGRID:112706 SUV39H1 BioGRID PMID: 24104479
Affinity Capture-MS
BioGRID:111700 BioGRID:198530 Serpinh1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:202142 Slc25a3 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:198105 Slc25a4 BioGRID PMID: 18307411
Affinity Capture-Luminescence
BioGRID:111700 BioGRID:211376 Smurf2 BioGRID PMID: 19379695
Affinity Capture-MS
BioGRID:111700 BioGRID:208002 Snd1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:203379 Snrpd1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:203498 Srm BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:125037 TBC1D31 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:116629 TCF25 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:114983 TCL1B BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:112810 TCP1 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:933977 TDRD15 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:114900 TECR BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:119942 TERF2IP BioGRID PMID: 31685992
Synthetic Growth Defect
BioGRID:111700 BioGRID:112914 THBD BioGRID PMID: 24104479
Reconstituted Complex
BioGRID:111700 BioGRID:121436 THOC2 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:124047 THOC3 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:122605 THOC6 BioGRID PMID: 31685992
Negative Genetic
BioGRID:111700 BioGRID:120647 TMCO6 BioGRID PMID: 35559673
Two-hybrid
BioGRID:111700 BioGRID:114145 TMEFF1 BioGRID PMID: 24412244
Affinity Capture-Western; Biochemical Activity
BioGRID:111700 BioGRID:114207 TNKS BioGRID PMID: 25547115
Affinity Capture-Western; Biochemical Activity
BioGRID:111700 BioGRID:123257 TNKS2 BioGRID PMID: 25547115
Affinity Capture-MS
BioGRID:111700 BioGRID:131973 TOPAZ1 BioGRID PMID: 30631154
Affinity Capture-Western; Reconstituted Complex
BioGRID:111700 BioGRID:113010 TP53 BioGRID PMID: 24141722,18339852,14559824,12620407
Affinity Capture-Western; Protein-peptide; Reconstituted Complex
BioGRID:111700 BioGRID:113011 TP53BP1 BioGRID PMID: 31217297
Affinity Capture-MS
BioGRID:111700 BioGRID:117952 TPK1 BioGRID PMID: 33961781
Negative Genetic
BioGRID:111700 BioGRID:123063 TRAPPC13 BioGRID PMID: 28319085
Positive Genetic
BioGRID:111700 BioGRID:112299 TRAPPC2 BioGRID PMID: 28319085
Positive Genetic
BioGRID:111700 BioGRID:119681 TRAPPC2L BioGRID PMID: 28319085
Synthetic Growth Defect
BioGRID:111700 BioGRID:114333 TRIM24 BioGRID PMID: 24104479
Affinity Capture-Western; Biochemical Activity
BioGRID:111700 BioGRID:113500 TRIM25 BioGRID PMID: 34416231,33931764,32196840
Affinity Capture-Western
BioGRID:111700 BioGRID:111919 TRIM27 BioGRID PMID: 31719796
Reconstituted Complex
BioGRID:111700 BioGRID:115457 TRIM28 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:110678 TRIM37 BioGRID PMID: 33194618
Affinity Capture-Western
BioGRID:111700 BioGRID:130421 TRIM59 BioGRID PMID: 32165307
Synthetic Growth Defect
BioGRID:111700 BioGRID:123541 TRIM8 BioGRID PMID: 24104479
Two-hybrid
BioGRID:111700 BioGRID:119593 TRMO BioGRID PMID: 24412244
Affinity Capture-MS
BioGRID:111700 BioGRID:123267 TSGA10 BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:126962 TTBK2 BioGRID PMID: 15717329
Synthetic Growth Defect
BioGRID:111700 BioGRID:122175 TTC31 BioGRID PMID: 24104479
Synthetic Growth Defect
BioGRID:111700 BioGRID:113603 TUBA1A BioGRID PMID: 24104479
Reconstituted Complex
BioGRID:111700 BioGRID:115651 TUBA1B BioGRID PMID: 26561776
Affinity Capture-MS
BioGRID:111700 BioGRID:124259 TUBA1C BioGRID PMID: 21532586
Affinity Capture-MS
BioGRID:111700 BioGRID:113129 TUBA3C BioGRID PMID: 21532586
Reconstituted Complex
BioGRID:111700 BioGRID:128444 TUBB BioGRID PMID: 26561776
Affinity Capture-RNA
BioGRID:111700 BioGRID:113131 TUBB2A BioGRID PMID: 21532586
Affinity Capture-MS
BioGRID:111700 BioGRID:115654 TUBB3 BioGRID PMID: 21532586
Affinity Capture-MS; Reconstituted Complex
BioGRID:111700 BioGRID:115656 TUBB4B BioGRID PMID: 26561776,21532586
Reconstituted Complex
BioGRID:111700 BioGRID:113135 TUFM BioGRID PMID: 31685992,26561776
Biochemical Activity
BioGRID:111700 BioGRID:113142 TWIST1 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:113146 TXN BioGRID PMID: 26561776
Synthetic Growth Defect
BioGRID:111700 BioGRID:119253 TXNDC11 BioGRID PMID: 24104479
Negative Genetic
BioGRID:111700 BioGRID:113149 TYMS BioGRID PMID: 35559673
Affinity Capture-MS
BioGRID:111700 BioGRID:204044 Tcp1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:204290 Tpi1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:204373 Tuba1b BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:216203 Tubb2b BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:230642 Tubb4b BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:785892 Tubb4b-ps1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:204381 Tubb5 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:212561 Tubb6 BioGRID PMID: 18307411
Affinity Capture-MS; Reconstituted Complex
BioGRID:111700 BioGRID:113157 U2AF1 BioGRID PMID: 32249768,31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:113165 UBA1 BioGRID PMID: 32249768
Affinity Capture-MS
BioGRID:111700 BioGRID:130617 UBAC2 BioGRID PMID: 35271311
Synthetic Growth Defect
BioGRID:111700 BioGRID:115227 UBAP2L BioGRID PMID: 24104479
Affinity Capture-Western; PCA
BioGRID:111700 BioGRID:113164 UBC BioGRID PMID: 24798731
Synthetic Growth Defect
BioGRID:111700 BioGRID:113169 UBE2D1 BioGRID PMID: 24104479
Affinity Capture-Western
BioGRID:111700 BioGRID:113177 UBE2I BioGRID PMID: 22713753,12620973
Affinity Capture-Western
BioGRID:111700 BioGRID:113180 UBE2L3 BioGRID PMID: 12620973
Affinity Capture-MS; Affinity Capture-Western
BioGRID:111700 BioGRID:118150 UBE2S BioGRID PMID: 34785642,30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:124418 UBL7 BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:119239 UBXN1 BioGRID PMID: 32249768
Reconstituted Complex
BioGRID:111700 BioGRID:111908 UPF1 BioGRID PMID: 31685992
Negative Genetic
BioGRID:111700 BioGRID:113241 USP1 BioGRID PMID: 35559673
Affinity Capture-MS; Affinity Capture-Western
BioGRID:111700 BioGRID:114554 USP10 BioGRID PMID: 34416231,30056112,28852924,24270891
Affinity Capture-Western
BioGRID:111700 BioGRID:113866 USP11 BioGRID PMID: 31592114
Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Co-localization; Reconstituted Complex
BioGRID:111700 BioGRID:114465 USP13 BioGRID PMID: 33378983,31200745,26453058,26280536,24270891
Affinity Capture-Western
BioGRID:111700 BioGRID:118895 USP25 BioGRID PMID: 34805185
Affinity Capture-MS
BioGRID:111700 BioGRID:115939 USP39 BioGRID PMID: 24270891
Affinity Capture-MS
BioGRID:111700 BioGRID:113221 USP4 BioGRID PMID: 24270891
Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
BioGRID:111700 BioGRID:113622 USP7 BioGRID PMID: 31685992,29117568,26280536,24270891,24063548
Affinity Capture-MS; Affinity Capture-Western
BioGRID:111700 BioGRID:114555 USP8 BioGRID PMID: 24270891
Affinity Capture-Western; Reconstituted Complex
BioGRID:111700 BioGRID:113867 USP9X BioGRID PMID: 31685992
Negative Genetic
BioGRID:111700 BioGRID:115503 USPL1 BioGRID PMID: 35559673
Two-hybrid
BioGRID:111700 BioGRID:116026 UTP14A BioGRID PMID: 16169070
Reconstituted Complex
BioGRID:111700 BioGRID:113245 UTRN BioGRID PMID: 26561776
Affinity Capture-MS
BioGRID:111700 BioGRID:204410 Uba1 BioGRID PMID: 18307411
Affinity Capture-MS
BioGRID:111700 BioGRID:204433 Ugdh BioGRID PMID: 18307411
Negative Genetic
BioGRID:111700 BioGRID:113269 VHL BioGRID PMID: 28319113
Positive Genetic
BioGRID:111700 BioGRID:116443 VPS45 BioGRID PMID: 28319085
Negative Genetic
BioGRID:111700 BioGRID:120563 VPS53 BioGRID PMID: 28319085
Affinity Capture-MS
BioGRID:111700 BioGRID:234661 Vcp BioGRID PMID: 18307411
Synthetic Growth Defect
BioGRID:111700 BioGRID:115226 WASHC5 BioGRID PMID: 24104479
Affinity Capture-Western; Co-localization; Reconstituted Complex
BioGRID:111700 BioGRID:116272 WDR5 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:119939 WNT4 BioGRID PMID: 15717329
Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
BioGRID:111700 BioGRID:116243 WWP1 BioGRID PMID: 33470109,25547115,21532586
Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
BioGRID:111700 BioGRID:116244 WWP2 BioGRID PMID: 35780838,35331737,33039560,31592114,30849479,30016585,28475870,27852060,27295432,24063548,22427670,21532586,15717329
Affinity Capture-Western; Biochemical Activity
BioGRID:111700 BioGRID:106828 XIAP BioGRID PMID: 22427670,19473982
Affinity Capture-MS
BioGRID:111700 BioGRID:113345 XPC BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:113353 XRCC5 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:108822 XRCC6 BioGRID PMID: 31685992
Two-hybrid
BioGRID:111700 BioGRID:115441 YAF2 BioGRID PMID: 21653829
Biochemical Activity
BioGRID:111700 BioGRID:115684 YAP1 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:113357 YES1 BioGRID PMID: 26561776
Synthetic Growth Defect
BioGRID:111700 BioGRID:115954 YME1L1 BioGRID PMID: 24104479
Reconstituted Complex
BioGRID:111700 BioGRID:122321 YTHDC2 BioGRID PMID: 31685992
Reconstituted Complex
BioGRID:111700 BioGRID:119543 YTHDF2 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:120956 ZC3H15 BioGRID PMID: 30631154
Negative Genetic
BioGRID:111700 BioGRID:118841 ZC3H7A BioGRID PMID: 35559673
Affinity Capture-MS
BioGRID:111700 BioGRID:115709 ZER1 BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:117299 ZNF318 BioGRID PMID: 30631154
Reconstituted Complex
BioGRID:111700 BioGRID:129936 ZNF326 BioGRID PMID: 31685992
Affinity Capture-MS
BioGRID:111700 BioGRID:131374 ZNF391 BioGRID PMID: 30631154
Affinity Capture-MS
BioGRID:111700 BioGRID:125966 ZNF787 BioGRID PMID: 15717329
Affinity Capture-MS
BioGRID:111700 BioGRID:122432 ZSCAN18 BioGRID PMID: 33961781
GENERAL GENE INFO
-------------------------------------------------------------------------------------------------
Marker
D10S610 (e-PCR) Links:UniSTS:23815
PMC20246P1 (e-PCR) Links:UniSTS:271890
STS-H71499 (e-PCR) Links:UniSTS:5911
G19918 (e-PCR) Links:UniSTS:77108
D10S221 (e-PCR) Links:UniSTS:35654
RH66859 (e-PCR) Links:UniSTS:92239
RH92455 (e-PCR) Links:UniSTS:85842
RH122960 (e-PCR) Links:UniSTS:135257
RH122724 (e-PCR) Links:UniSTS:133995
AFMA086WG9 (e-PCR) Links:UniSTS:2163
PTEN_234 (e-PCR) Links:UniSTS:468624
MARC_17017-17018:1023291848:1 (e-PCR) Links:UniSTS:268185
Pten (e-PCR), detects polymorphism Links:UniSTS:144288
WI-18385 (e-PCR) Links:UniSTS:55210
STS-W73720 (e-PCR) Links:UniSTS:71597
PMC154149P1 (e-PCR) Links:UniSTS:271292
PMC88770P1 (e-PCR) Links:UniSTS:273605
PMC88770P2 (e-PCR) Links:UniSTS:273606
PMC88770P3 (e-PCR) Links:UniSTS:273607
RH103681 (e-PCR) Links:UniSTS:98006
SHGC-111133 (e-PCR) Links:UniSTS:168163
RH79866 (e-PCR) Links:UniSTS:90866
Related pseudogene(s)
1 foundReview record(s) in Gene, http://130.14.22.59/gene/?Term=related_functional_gene_5728%5Bgroup%5D
Clone Names
MGC11227
Homology
Orthologs from Annotation Pipeline (/gene/?Term=ortholog_gene_5728[group]):
Orthologs
Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
Function GO ID Evidence
-------------------------------------------------------------------------------------------------
enables PDZ domain binding GO:0000000 PMID: 10646847,10760291
enables anaphase-promoting complex bindi... GO:0000000 PMID: 21241890
enables enzyme binding GO:0000000 PMID: 16845383
enables identical protein binding GO:0000000 PMID: 24766807
enables inositol-1,3,4,5-tetrakisphospha... GO:0000000 PMID: 9593664
enables lipid binding GO:0000000 -
enables myosin phosphatase activity GO:0000000 -
enables phosphatidylinositol-3,4,5-trisp... GO:0000000 PMID: 21873635
enables phosphatidylinositol-3,4,5-trisp... GO:0000000 PMID: 9593664,9811831
enables phosphatidylinositol-3,4,5-trisp... GO:0000000 -
enables phosphatidylinositol-3,4-bisphos... GO:0000000 PMID: 9811831
enables phosphatidylinositol-3,4-bisphos... GO:0000000 -
enables phosphatidylinositol-3-phosphate... GO:0000000 PMID: 9811831
enables phosphoprotein phosphatase activ... GO:0000000 PMID: 21241890
enables protein binding GO:0000000 PMID: 15355975,15951562,16456542,17242191,17274640,19345329,19369943,19473982,19903340,21241890,21653829,21804599,23514585,23940795,24012959,24656772,25007873,25241761
enables protein serine/threonine phospha... GO:0000000 PMID: 9256433
enables protein tyrosine phosphatase act... GO:0000000 PMID: 21873635
enables protein tyrosine phosphatase act... GO:0000000 PMID: 9256433
enables ubiquitin-specific protease bind... GO:0000000 PMID: 26280536
Processs GO ID Evidence
-------------------------------------------------------------------------------------------------
involved_in apoptotic process GO:0000000 -
involved_in brain morphogenesis GO:0000000 -
involved_in canonical Wnt signaling path... GO:0000000 PMID: 20123964
involved_in cell migration GO:0000000 -
involved_in cell motility GO:0000000 PMID: 21873635
involved_in cellular response to electri... GO:0000000 PMID: 27919618
involved_in central nervous system devel... GO:0000000 -
involved_in central nervous system myeli... GO:0000000 -
involved_in central nervous system neuro... GO:0000000 -
involved_in dendritic spine morphogenesi... GO:0000000 -
involved_in dentate gyrus development GO:0000000 -
involved_in forebrain morphogenesis GO:0000000 -
involved_in heart development GO:0000000 -
involved_in learning or memory GO:0000000 -
involved_in locomotor rhythm GO:0000000 -
involved_in locomotory behavior GO:0000000 -
involved_in multicellular organismal res... GO:0000000 -
involved_in negative regulation of ERK1 ... GO:0000000 -
involved_in negative regulation of G1/S ... GO:0000000 PMID: 21241890
involved_in negative regulation of axono... GO:0000000 -
involved_in negative regulation of cell ... GO:0000000 PMID: 10918569
involved_in negative regulation of cell ... GO:0000000 PMID: 9616126,17880912,21573166
involved_in negative regulation of cell ... GO:0000000 PMID: 21873635
involved_in negative regulation of cell ... GO:0000000 PMID: 19057511
involved_in negative regulation of cell ... GO:0000000 PMID: 10468583,17880912
involved_in negative regulation of cell ... GO:0000000 -
involved_in negative regulation of cellu... GO:0000000 PMID: 21241890
involved_in negative regulation of cycli... GO:0000000 PMID: 21241890
involved_in negative regulation of dendr... GO:0000000 -
involved_in negative regulation of epith... GO:0000000 PMID: 27919618
involved_in negative regulation of excit... GO:0000000 -
involved_in negative regulation of focal... GO:0000000 PMID: 9616126
involved_in negative regulation of kerat... GO:0000000 PMID: 27919618
involved_in negative regulation of neuro... GO:0000000 PMID: 28008308
involved_in negative regulation of organ... GO:0000000 -
involved_in negative regulation of pepti... GO:0000000 PMID: 10918569
involved_in negative regulation of phosp... GO:0000000 PMID: 16762633
involved_in negative regulation of phosp... GO:0000000 PMID: 18082964
acts_upstream_of_or_within negative regu... GO:0000000 PMID: 26280536
involved_in negative regulation of prote... GO:0000000 PMID: 10760291,21573166,22879939
involved_in negative regulation of prote... GO:0000000 -
involved_in negative regulation of prote... GO:0000000 PMID: 20123964
involved_in negative regulation of prote... GO:0000000 -
involved_in negative regulation of synap... GO:0000000 -
involved_in negative regulation of vascu... GO:0000000 PMID: 26208095
involved_in negative regulation of wound... GO:0000000 PMID: 27919618
involved_in neuron-neuron synaptic trans... GO:0000000 -
involved_in phosphatidylinositol 3-kinas... GO:0000000 PMID: 21873635
involved_in phosphatidylinositol 3-kinas... GO:0000000 PMID: 9593664
involved_in phosphatidylinositol biosynt... GO:0000000 -
involved_in phosphatidylinositol dephosp... GO:0000000 PMID: 21873635
involved_in phosphatidylinositol dephosp... GO:0000000 PMID: 9593664,9811831
involved_in phosphatidylinositol dephosp... GO:0000000 PMID: 21828076
involved_in positive regulation of DNA-b... GO:0000000 PMID: 20123964
involved_in positive regulation of TRAIL... GO:0000000 -
involved_in positive regulation of cell ... GO:0000000 -
involved_in positive regulation of excit... GO:0000000 -
involved_in positive regulation of ubiqu... GO:0000000 PMID: 21241890
involved_in positive regulation of ubiqu... GO:0000000 PMID: 21241890
involved_in postsynaptic density assembl... GO:0000000 -
involved_in prepulse inhibition GO:0000000 -
involved_in presynaptic membrane assembl... GO:0000000 -
involved_in protein dephosphorylation GO:0000000 PMID: 21873635
involved_in protein dephosphorylation GO:0000000 PMID: 9256433
involved_in protein dephosphorylation GO:0000000 PMID: 9367992
involved_in protein kinase B signaling GO:0000000 -
involved_in protein stabilization GO:0000000 PMID: 20123964
involved_in regulation of cellular compo... GO:0000000 -
involved_in regulation of neuron project... GO:0000000 -
involved_in regulation of protein kinase... GO:0000000 PMID: 21873635
involved_in regulation of protein stabil... GO:0000000 PMID: 10866658
involved_in rhythmic synaptic transmissi... GO:0000000 -
involved_in social behavior GO:0000000 -
involved_in synapse assembly GO:0000000 -
involved_in synapse maturation GO:0000000 -
Component GO ID Evidence
-------------------------------------------------------------------------------------------------
located_in PML body GO:0000000 -
located_in Schmidt-Lanterman incisure GO:0000000 -
located_in apical plasma membrane GO:0000000 PMID: 24862762
is_active_in cell projection GO:0000000 PMID: 21873635
located_in cell projection GO:0000000 PMID: 10760291,25007873
located_in cytoplasm GO:0000000 PMID: 9187108,10760291,10940933,21241890,24862762
located_in cytoplasm GO:0000000 PMID: 9367992
located_in cytoplasmic side of plasma me... GO:0000000 PMID: 10940933
is_active_in cytosol GO:0000000 PMID: 21873635
located_in cytosol GO:0000000 -
located_in cytosol GO:0000000 -
located_in dendritic spine GO:0000000 -
located_in extracellular region GO:0000000 -
located_in myelin sheath adaxonal region GO:0000000 -
located_in neuron projection GO:0000000 -
located_in nucleoplasm GO:0000000 -
located_in nucleoplasm GO:0000000 -
is_active_in nucleus GO:0000000 PMID: 21873635
located_in nucleus GO:0000000 PMID: 17218261,21241890,24862762
is_active_in plasma membrane GO:0000000 PMID: 21873635
located_in plasma membrane GO:0000000 PMID: 10760291
located_in postsynaptic density GO:0000000 -
GENERAL PROTEIN INFORMATION
-------------------------------------------------------------------------------------------------
Preferred Names
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Names
MMAC1 phosphatase and tensin homolog deleted on chromosome 10
PTEN variant PTEN-K267Rfs*9
PTEN variant PTEN-L247*
PTEN variant PTEN-R234Afs*11
PTENepsilon
mitochondrial PTENalpha
mitochondrial phosphatase and tensin protein alpha
mutated in multiple advanced cancers 1
phosphatase and tensin-like protein
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
protein tyrosine phosphatase
NP_000305.3
EC 3.1.3.16
EC 3.1.3.48
EC 3.1.3.67
NP_001291646.4
EC 3.1.3.16
EC 3.1.3.48
EC 3.1.3.67
NP_001291647.1
EC 3.1.3.16
EC 3.1.3.48
EC 3.1.3.67
NCBI REFERENCE SEQUENCES (RefSeq)
-------------------------------------------------------------------------------------------------
RefSeqs maintained independently of Annotated Genomes
These reference sequences exist independently of genome builds.
These reference sequences are curated independently of the genome annotation cycle,
so their versions may not match the RefSeq versions in the current genome build.
Identify version mismatches by comparing the version of the RefSeq in this section to
the one reported in Genomic regions, transcripts, and products section above.
Genomic
NG_007466.2 RefSeqGene
Range 5000..113491
Download GenBank FASTA Sequence Viewer (Graphics)
mRNA and Protein(s)
NM_000314.8 → NP_000305.3 REVIEWEDphosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform PTEN
See proteins identical to NP_000305.3 at http://130.14.22.59/ipg/NP_000305.3/
Description: Transcript Variant: This variant (1) encodes mu...
Source sequence(s): AC063965
Consensus CDS: CCDS31238.1
UniProtKB/TrEMBL: F6KD01
UniProtKB/Swiss-Prot: P60484
UniProtKB/Swiss-Prot: Q6ICT7
Related Ensembl: ENSP00000361021.3, ENST00000371953.8
Conserved Domains (2)summary
cd14509:
Location:24 - 181
PTP_PTEN; protein tyrosine phosphatase-like catalytic domain of phosphatase and tensin homolog
pfam10409:
Location:188 - 349
PTEN_C2; C2 domain of PTEN tumor-suppressor protein
NM_001304717.5 → NP_001291646.4 REVIEWEDphosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform PTEN-L
Description: Transcript Variant: This variant (1) encodes mu...
Source sequence(s): AA836562, AC063965, BC005821, U92436
Related Ensembl: ENSP00000509861.1, ENST00000693560.1
NM_001304718.2 → NP_001291647.1 REVIEWEDphosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 3
See proteins identical to NP_001291647.1 at http://130.14.22.59/ipg/NP_001291647.1/
Description: Transcript Variant: This variant (2) both conta...
Source sequence(s): AA836562, AC063965, BC005821, JF268690, U92436
UniProtKB/Swiss-Prot: P60484
Conserved Domains (1)summary
pfam10409:
Location:1 - 152
PTEN_C2; C2 domain of PTEN tumor-suppressor protein
RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_03
The following sections contain reference sequences that belong to a specific genome build.
This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which
this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both
reference and alternate assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
NC_000010.11 Reference GRCh38.p14 Primary Assembly
Range 87863624..87971929
Download GenBank FASTA Sequence Viewer (Graphics)
Reference GRCh38.p14 PATCHES
Genomic
NW_013171807.1 Reference GRCh38.p14 PATCHES
Range 79448..187718
Download GenBank FASTA Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
NC_060934.1 Alternate T2T-CHM13v2.0
Range 88747527..88855829
Download GenBank FASTA Sequence Viewer (Graphics)
RELATED SEQUENCES
-------------------------------------------------------------------------------------------------
Nucleotide Protein
-------------------------------------------------------------------------------------------------
genomic AB009903.1 BAA24090.1
genomic AC022016.7(81261..163030) None
genomic AC063965.8(76827..185191) None
genomic AF067844.1 AAD13528.1
genomic AF406618.1 None
genomic AH005966.2 AAC08699.1
genomic AH007803.2 AAD38372.1
genomic CH471066.2 EAW50172.1
EAW50173
EAW50174
EAW50175
genomic CP068268.2(88747528..88855830) None
genomic DQ073384.1 AAY57327.1
genomic HM849624.1 ADM26749.1
genomic HM849628.1 ADM26753.1
genomic HM849629.1 ADM26754.1
genomic HM849630.1 ADM26755.1
genomic HM849631.1 ADM26756.1
genomic HM849634.1 ADM26759.1
genomic JA692802.1 CCF23296.1
genomic JA902567.1 CCV19970.1
genomic JB074276.1 CCV66764.1
genomic JB759376.1 CDI44160.1
genomic JQ037769.1 AEZ67434.1
genomic JQ037770.1 AEZ67435.1
genomic JQ037771.1 AEZ67436.1
genomic JQ037772.1 AEZ67437.1
genomic JQ037773.1 AEZ67438.1
genomic JQ037774.1 AEZ67429.1
genomic JQ037775.1 AEZ67430.1
genomic JQ037776.1 AEZ67431.1
genomic JQ037777.1 AEZ67432.1
genomic JQ037778.1 AEZ67433.1
genomic KF455271.1 None
genomic KT886842.1 AMQ76357.1
AMQ76358
AMQ76359
genomic MG874045.1 AVE00942.1
genomic MG911695.1 AVZ47052.1
genomic MZ615337.1 QYC61795.1
genomic MZ615338.1 QYC61796.1
genomic MZ615339.1 QYC61797.1
genomic OK357121.1 UCR97803.1
genomic OK357122.1 UCR97804.1
genomic OK357123.1 UCR97805.1
genomic OK357124.1 UCR97806.1
genomic OK357125.1 UCR97807.1
genomic OK357126.1 UCR97808.1
genomic OK357127.1 UCR97809.1
genomic OK357128.1 UCR97810.1
genomic OK357129.1 UCR97811.1
genomic OK357130.1 UCR97812.1
genomic OK357131.1 UCR97813.1
genomic OK357132.1 UCR97814.1
genomic OK357133.1 UCR97815.1
genomic OK357134.1 UCR97816.1
genomic OK357135.1 UCR97817.1
genomic OK357136.1 UCR97818.1
genomic OK357137.1 UCR97819.1
genomic OK357138.1 UCR97820.1
genomic OK357139.1 UCR97821.1
genomic OK357140.1 UCR97822.1
genomic OK357141.1 UCR97823.1
mRNA AA017584.1 None
mRNA AA836562.1 None
mRNA AI825848.1 None
mRNA AK021619.1 None
mRNA AK024986.1 None
mRNA AK124525.1 None
mRNA AK130076.1 None
mRNA AK313581.1 BAG36351.1
mRNA BC005821.2 AAH05821.1
mRNA BG772190.1 None
mRNA BK008756.1 DAA64601.1
mRNA CA944942.1 None
mRNA CR450306.1 CAG29302.1
mRNA JF268690.1 ADZ48535.1
mRNA KJ534922.1 AHW56562.1
mRNA KX398936.1 ARB02560.1
mRNA MK783286.1 QID04980.1
mRNA MW048523.1 UGU37858.1
mRNA U92436.1 AAC51182.1
mRNA U93051.1 AAC51183.1
mRNA U96180.1 AAB66902.1
Protein Accession Links
-------------------------------------------------------------------------------------------------
P60484.1 GenPept(/protein/42560209) UniProtKB/Swiss-Prot:P60484
GENE LINKOUT
-------------------------------------------------------------------------------------------------
The following LinkOut(www.ncbi.nlm.nih.gov/projects/linkout/index.html) resources
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Molecular Biology Databases
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(Free resource) (free) BioGRID Open Repository of CRISPR Screens (ORCS)
BioGRID CRISPR Screen Phenotypes (85 hits/1159 screens)BioGRID CRISPR Screen Phenotypes (85 hits/1159 screens)
(Free resource) (free) CREB Target Gene Database
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(Free resource) (free) Eukaryotic Promoter Database
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(Free resource) (free) GenAge Database of Aging Related Genes
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(Order form) GenScript latest version of gene cDNA ORF Clone
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(Free resource) (free) GlyGen glycoinformatics resource
GlyGen glycoinformatics resource
(Free resource) (free) Guide to Pharmacology
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(Free resource) (Free registration required) (free) Human Gene Mutation Database
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(Free resource) (free) Human eFP Browser
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(Free resource) (free) InnateDB
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(Free resource) (free) InterMine
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(Free resource) (free) Kyoto Encyclopedia of Genes and Genomes
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(Free resource) (free) Monarch Initiative
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(Free resource) (free) OMA Browser: Orthologous MAtrix
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(Free resource) (free) OrthoDB catalog of orthologs
OrthologsOrthologs
(Free resource) (free) Pharmacogenomics Knowledge Base
Annotated Pharmacogenomic Information for PTEN [PharmGKB]Annotated Pharmacogenomic Information for PTEN [PharmGKB]
(Free resource) (free) PhosphoSitePlus
PhosphoSitePlus® - comprehensive post-translational modification resourcePhosphoSitePlus® - comprehensive post-translational modification resource
(Free resource) (free) Protein Ontology Consortium
Protein Ontology Consortium
(Free resource) (free) The Gene Wiki
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(Free resource) (free) The Weizmann Institute of Science GeneCards and MalaCards databases
GeneCard for PTENGeneCard for PTEN
(Free resource) (free) Vertebrate Genome Annotation (VEGA) database
Vertebrate Genome Annotation (VEGA) database
(Free resource) (free) iRefWeb - iRefIndex release 9.0 - Consolidated Interactome
iRefWeb - iRefIndex release 9.0 - Consolidated Interactome
Research Materials
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LSBio PTEN ProteinsLSBio PTEN Proteins
(Order form) NITE Biological Resource Center
Human cDNA clones used in NEDO Project / AK124525Human cDNA clones used in NEDO Project / AK124525Human cDNA clones used in NEDO Project / AK313581Human cDNA clones used in NEDO Project / AK313581Human cDNA clones used in NEDO Project / AK021619Human cDNA clones used in NEDO Project / AK021619
(Order form) Sino Biological Inc.
Human PTEN Gene cDNA Clone (full-length ORF Clone), expression ready, Myc-taggedHuman PTEN Gene cDNA Clone (full-length ORF Clone), expression ready, Myc-taggedHuman PTEN Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-taggedHuman PTEN Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-taggedHuman PTEN Gene cDNA Clone (full-length ORF Clone), expression ready, untaggedHuman PTEN Gene cDNA Clone (full-length ORF Clone), expression ready, untagged
Tools
(Free resource) (free) GeneMANIA
GeneMANIA
