CDH1 cadherin 1[Homo sapiens]
Gene ID: 999, updated on 29-Mar-2023
SUMMARY
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Official Symbol: CDH1 (provided by HGNC)
Official full name: cadherin 1 (provided by HGNC)
Primary source: HGNC:HGNC:1748
See related: Ensembl:ENSG00000039068; MIM:192090; AllianceGenome:HGNC:1748
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324
Summary: This gene encodes a classical cadherin of the cadherin superfamily. Alternative
splicing results in multiple transcript variants, at least one of which encodes a
preproprotein that is proteolytically processed to generate the mature
glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of
five extracellular cadherin repeats, a transmembrane region and a highly
conserved cytoplasmic tail. Mutations in this gene are correlated with gastric,
breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is
thought to contribute to cancer progression by increasing proliferation,
invasion, and/or metastasis. The ectodomain of this protein mediates bacterial
adhesion to mammalian cells and the cytoplasmic domain is required for
internalization. This gene is present in a gene cluster with other members of the
cadherin family on chromosome 16. [provided by RefSeq, Nov 2015]
Annotation information: Note: CDH1 (GeneID 999) and FZR1 (GeneID 51343) share the CDH1 symbol. CDH1 is
sometimes used as an abbreviation for 'CDC20 homolog 1' which is an alternate
name for the FZR1 gene and thus can be confused with the official symbol for
cadherin 1 (CDH1). [16 Jul 2018]
Orthologsall (/gene/?Term=ortholog_gene_999[group]), mouse (https://www.ncbi.nlm.nih.gov/gene/12550)
GENOMIC CONTEXT
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Location: 16q22.1
Annotation release Status Assembly Chromosome Location
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RS_2023_03 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (68737292..68835537)
RS_2023_03 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (74533467..74631804)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (68771195..68869440)
Exont count: 16
BIBLIOGRAPHY
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Related Articles in PubMed
1. [Influence of E-cadherin methylation on prognosis in children with acute
lymphoblastic leukemia]. Qi FQ, . Zhongguo Dang Dai Er Ke Za Zhi, 2023 Jan 15,
PMID 36655663., Free PMC Article(s): PMC9893830
2. Low expression of E-Cadherin and CDH1 variants associated with diffuse gastric
cancer. García-Ruvalcaba A, . Rev Invest Clin, 2023 Feb 20, PMID 36652613.
3. Soluble E-cadherin: A marker of genital epithelial disruption. Liu R, . Am J
Reprod Immunol, 2023 Mar, PMID 36593681.
4. The Identification of Large Rearrangements Involving Intron 2 of the CDH1 Gene in
BRCA1/2 Negative and Breast Cancer Susceptibility. Ben Aissa-Haj J, . Genes
(Basel), 2022 Nov 25, PMID 36553480., Free PMC Article(s): PMC9778491
5. Clinical and prognostic features of E-cadherin in adenocarcinoma of the
esophagogastric junction patients. Hu K, . Eur J Cancer Prev, 2023 Mar 1, PMID
36484275.
6. Soluble E-cadherin promotes invasiveness of neoplastic cells in salivary gland
carcinoma ex pleomorphic adenoma. Chen W, . J Oral Pathol Med, 2023 Jan, PMID
36445289.
PHENOTYPES
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Review eQTL and phenotype association data in this region using PheGenI
http://www.ncbi.nlm.nih.gov/gap/PheGenI?chr=16&from=68737291&fromto=68737291+68835536&tab=0
Associated conditions
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Description Tests
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Blepharocheilodontic syndrome 1
MedGen: C4551988 OMIM: 119580 GeneReviews: Not available
Endometrial carcinoma
MedGen: C0476089 OMIM: 608089 GeneReviews: Not available
Familial cancer of breast
MedGen: C0346153 OMIM: 114480 GeneReviews: BRCA1- and BRCA2-Associated Hereditary Breast and Ovarian Cancer
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.
GeneReviews: Not available
Hereditary diffuse gastric adenocarcinoma
MedGen: C1708349 OMIM: 137215 GeneReviews: Hereditary Diffuse Gastric Cancer
Malignant tumor of prostate
MedGen: C0376358 OMIM: 176807 GeneReviews: Not available
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer.
GeneReviews: Not available
Neoplasm of ovary
MedGen: C0919267 OMIM: 167000 GeneReviews: Not available
Copy number response
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Copy number response
Triplosensitivity
No evidence available (Last evaluated 2020-04-10)
ClinGen Genome Curation Page(https://www.ncbi.nlm.nih.gov/projects/dbvar/ISCA/isca_gene.cgi?sym=CDH1)Haploinsufficency
Sufficient evidence for dosage pathogenicity (Last evaluated 2020-04-10)
ClinGen Genome Curation Page(https://www.ncbi.nlm.nih.gov/projects/dbvar/ISCA/isca_gene.cgi?sym=CDH1)
PubMed(/pubmed/19168852,24037103,26182300)
VARIATION
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See variants in ClinVar, http://130.14.22.106/sites/gene/clinvar/?term=CDH1[gene]
See studies and variants in dbVar, http://130.14.22.106/sites/gene
See Variation Viewer (GRCh37.p13), http://130.14.22.106/sites/gene/variation/view/?q=999[geneid]&assm=GCF_000001405.25
See Variation Viewer (GRCh38), http://130.14.22.106/sites/gene/variation/view/?q=999[geneid]
Genotypes
See SNP Geneview Report, http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2FSNP%2Fsnp_ref.cgi%3FlocusId%3D999
See 1000 Genomes Browser (GCF_000001405.25), http://130.14.22.106/sites/gene/variation/tools/1000genomes/?q=999[geneid]&assm=GCF_000001405.25
HIV-1 INTERACTIONS
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Protein interactions
Protein Gene Interaction Pubs
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/protein/28876544 /gene/155971 HIV-1 gp120 inhibits the expression of E-cadherin and changes its localization from cell membrane to cytoplasm in polarized oral epithelial cells 24586397
/protein/9629358 /gene/155871 HIV-1 Tat C treated human brain microvascular endothelial cells result in downregulation and dissociation of VE-PTP and SHP2 from VE-cadherin 24965120
/protein/9629358 /gene/155871 HIV-1 Tat C induces phosphorylation of adherens junction proteins VE-cadherin and beta-catenin in human brain microvascular endothelial cells 24965120
/protein/9629358 /gene/155871 HIV-1 Tat inhibits the expression of E-cadherin and changes its localization from cell membrane to cytoplasm in polarized oral epithelial cells 24586397
/protein/28872817 /gene/155807 HIV-1 Vpr-expressing Jurkat T cell clones showed upregulated expression of cadherin, suggesting a role of Vpr in modulating the cell adhesion process 10713718
/protein/9629366 /gene/155945 HIV-1 Vpu reduces the beta-catenin interaction with E-cadherin and the Vpu-mediated dissociation of beta-catenin with E-cadherin enhances particle release 18256147
Go to the HIV-1, Human Interaction Database: http://130.14.22.106/genome/viruses/retroviruses/hiv-1/interactions/
INTERACTION
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Description of Gene Interaction table
Product Interactant Other Gene Complex Source Pubs
-------------------------------------------------------------------------------------------------
TCF8 (deltaEF1) interacts with the CDH1 (E-cadherin) promoter.
NC_000016.8 NP_110378.2 ZEB1 BIND PMID: 15674322
E-cadherin interacts with caveolin-1.
NP_004351.1 NP_001744.2 CAV1 BIND PMID: 14706341
Beta-catenin interacts with E-cadherin. This interaction was modelled on a demonstrated interaction between beta-catenin from an unspecified species and human E-cadherin.
NP_004351.1 NP_001895.1 CTNNB1 BIND PMID: 15542433
Beta-catenin interacts with E-cadherin. This interaction was modelled on a demonstrated interaction between human beta-catenin and mouse E-cadherin.
NP_004351.1 NP_001895.1 CTNNB1 BIND PMID: 15294866
E-cadherin interacts with beta-catenin.
NP_004351.1 NP_001895.1 CTNNB1 BIND PMID: 14706341
CDH1(Ecad) interacts with P120ctn 3AC. This interaction was modelled on a demonstrated interaction between mouse CDH1(Ecad) and human P120ctn 3AC.
NP_004351.1 AAC39822.1 CTNND1 BIND PMID: 12707304
EGFR interacts with E-cadherin
NP_004351.1 NP_005219.2 EGFR BIND PMID: 14681060
P12830 P61158 ACTR3 HPRD PMID: 11882288
P12830 Q9UJX3 ANAPC7 HPRD PMID: 12956947
P12830 RICS ARHGAP32 HPRD PMID: 12531901
P12830 O00192 ARVCF HPRD PMID: 11058098
P12830 Q16790 CA9 HPRD PMID: 14567991
P12830 P42574 CASP3 HPRD PMID: 11076937
P12830 Q14790 CASP8 HPRD PMID: 12189238
P12830 E cadherin binding protein E7 CBLL1 HPRD PMID: 11836526
P12830 P12830 CDH1 HPRD PMID: 10202138
P12830 P55060 CSE1L HPRD PMID: 12061792
P12830 P68400 CSNK2A1 HPRD PMID: 10671552
P12830 P35221 CTNNA1 HPRD PMID: 11226248,7542250
P12830 P35222 CTNNB1 HPRD PMID: 17220478,17057644,11245482,11226248,9512503,7954478,7542250
P12830 O60716 CTNND1 HPRD PMID: 11226248,10931041,10629228,10409703,10225956,7651399,7542250
P12830 Q9UQB3 CTNND2 HPRD PMID: 9971746
P12830 P00533 EGFR HPRD PMID: 10969083
P12830 Q96RT1 ERBIN HPRD PMID: 11821434
P12830 P15311 EZR HPRD PMID: 10462524
P12830 Q03113 GNA12 HPRD PMID: 11136230
P12830 Q14344 GNA13 HPRD PMID: 11136230
P12830 P49841 GSK3B HPRD PMID: 10671552
P12830 Q13547 HDAC1 HPRD PMID: 15388328
P12830 Q92769 HDAC2 HPRD PMID: 15388328
P12830 P46940 IQGAP1 HPRD PMID: 10608854
P12830 P35568 IRS1 HPRD PMID: 11035789
P12830 P38570 ITGAE HPRD PMID: 12434297
P12830 P26010 ITGB7 HPRD PMID: 10837471
P12830 P14923 JUP HPRD PMID: 11226248,10959047,8207061,8074697,7890674,7542250,1639850
P12830 Q92597 NDRG1 HPRD PMID: 17220478
P12830 P98161 PKD1 HPRD PMID: 11274246
P12830 P62136 PPP1CA HPRD PMID: 17274640
P12830 P49768 PSEN1 HPRD PMID: 11953314,11226248,10635315
P12830 Q15678 PTPN14 HPRD PMID: 12808048
P12830 P10586 PTPRF HPRD PMID: 12095414
P12830 P28827 PTPRM HPRD PMID: 15588985,9531566,7642713
P12830 Q92930 RAB8B HPRD PMID: 12639940
P12830 P31350 RRM2 HPRD PMID: 12655059
P12830 P18206 VCL HPRD PMID: 9405455
Proximity Label-MS
BioGRID:107434 BioGRID:116520 AAK1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:120605 ABCF3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115324 ABI1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:110171 ABLIM1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116552 ABLIM3 BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:106555 ACADVL BioGRID PMID: 16212417
Proximity Label-MS
BioGRID:107434 BioGRID:122262 ACBD3 BioGRID PMID: 25468996
Affinity Capture-Western
BioGRID:107434 BioGRID:106586 ACTG1 BioGRID PMID: 9535896
Affinity Capture-Western; Co-fractionation
BioGRID:107434 BioGRID:106602 ACTN1 BioGRID PMID: 35831314,9535896
Affinity Capture-MS
BioGRID:107434 BioGRID:106596 ACTN4 BioGRID PMID: 16212417
Proximity Label-MS
BioGRID:107434 BioGRID:112731 ADAM17 BioGRID PMID: 25468996
Affinity Capture-Western
BioGRID:107434 BioGRID:114290 ADAM9 BioGRID PMID: 16336960
Proximity Label-MS
BioGRID:107434 BioGRID:106628 ADCY9 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:106631 ADD1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:106633 ADD3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116868 ADGRL2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:110447 AFDN BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:109503 AGFG1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:122494 AHNAK BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115846 AHSA1 BioGRID PMID: 25468996
Affinity Capture-Western
BioGRID:107434 BioGRID:121012 AJAP1 BioGRID PMID: 14595118
Two-hybrid
BioGRID:107434 BioGRID:106710 AKT1 BioGRID PMID: 24412244
Proximity Label-MS
BioGRID:107434 BioGRID:106728 ALDOA BioGRID PMID: 25468996
Co-fractionation
BioGRID:107434 BioGRID:115665 ANAPC10 BioGRID PMID: 35831314
Proximity Label-MS
BioGRID:107434 BioGRID:106785 ANK3 BioGRID PMID: 25468996
Affinity Capture-MS; Proximity Label-MS
BioGRID:107434 BioGRID:119959 ANLN BioGRID PMID: 33961781,25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:115795 ANP32B BioGRID PMID: 16212417
Proximity Label-MS
BioGRID:107434 BioGRID:106798 ANXA1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:106799 ANXA2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:106804 ANXA4 BioGRID PMID: 25468996
Two-hybrid
BioGRID:107434 BioGRID:124346 AOPEP BioGRID PMID: 24412244
Affinity Capture-MS
BioGRID:107434 BioGRID:114421 AP1M1 BioGRID PMID: 34591612
Affinity Capture-MS
BioGRID:107434 BioGRID:107587 AP2M1 BioGRID PMID: 24189400
Proximity Label-MS
BioGRID:107434 BioGRID:124065 ARFGAP2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:118084 ARFIP1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:117174 ARFIP2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:120397 ARGLU1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:106885 ARHGAP1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:125050 ARHGAP18 BioGRID PMID: 25468996
Affinity Capture-MS; Proximity Label-MS
BioGRID:107434 BioGRID:121636 ARHGAP21 BioGRID PMID: 34591612,25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121677 ARHGAP23 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114806 ARHGAP29 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115091 ARHGAP32 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:106887 ARHGAP5 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:106890 ARHGDIB BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116945 ARHGEF12 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:118085 ARHGEF16 BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:130905 ARMH1 BioGRID PMID: 35559673
Affinity Capture-Western
BioGRID:107434 BioGRID:115415 ARPC2 BioGRID PMID: 11882288
Proximity Label-MS
BioGRID:107434 BioGRID:131507 ARPIN BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:106914 ARVCF BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:119126 ASAP1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:106961 ATIC BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:106980 ATP2B1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:106983 ATP2B4 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116429 ATXN2L BioGRID PMID: 25468996
Reconstituted Complex
BioGRID:107434 BioGRID:114646 AURKB BioGRID PMID: 34509474
Proximity Label-MS
BioGRID:107434 BioGRID:114907 BAG3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115721 BAIAP2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121017 BAIAP2L1 BioGRID PMID: 25468996
Co-fractionation
BioGRID:107434 BioGRID:114934 BCAR1 BioGRID PMID: 35831314
Proximity Label-MS
BioGRID:107434 BioGRID:107071 BCL2L2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:107127 BMPR2 BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:107140 BRCA1 BioGRID PMID: 28319113
Proximity Label-MS
BioGRID:107434 BioGRID:107147 BSG BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:107164 BUB1 BioGRID PMID: 35559673
Proximity Label-MS
BioGRID:107434 BioGRID:115042 BZW1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:118793 BZW2 BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:131169 C16orf96 BioGRID PMID: 35559673
Affinity Capture-MS
BioGRID:107434 BioGRID:107169 C1QBP BioGRID PMID: 16212417
Proximity Label-MS
BioGRID:107434 BioGRID:122545 C1orf116 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:124327 C1orf198 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:122586 C1orf35 BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:937613 C2CD4D BioGRID PMID: 35559673
Proximity Label-MS
BioGRID:107434 BioGRID:571814 C6orf132 BioGRID PMID: 25468996
Affinity Capture-Western
BioGRID:107434 BioGRID:107223 CA9 BioGRID PMID: 14567991
Proximity Label-MS
BioGRID:107434 BioGRID:107251 CALD1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121382 CAMK1D BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:125875 CANT1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:107272 CAPG BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:110252 CAPRIN1 BioGRID PMID: 35559673
Proximity Label-MS
BioGRID:107434 BioGRID:107278 CAPS BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:107279 CAPZA1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:107282 CAPZB BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:120745 CARMIL1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121577 CASKIN2 BioGRID PMID: 25468996
Co-localization
BioGRID:107434 BioGRID:107286 CASP3 BioGRID PMID: 25241761
Proximity Label-MS
BioGRID:107434 BioGRID:107281 CAST BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:107315 CBL BioGRID PMID: 25468996
Affinity Capture-Western; Co-localization; FRET; Two-hybrid
BioGRID:107434 BioGRID:122960 CBLL1 BioGRID PMID: 29356040,28069439,22850631,22715382,22252131,21685945,19711372,18057010,16336960,11836526
Proximity Label-MS
BioGRID:107434 BioGRID:120212 CC2D1A BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:124658 CCDC120 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:125890 CCDC43 BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:124553 CCDC65 BioGRID PMID: 35559673
Proximity Label-MS
BioGRID:107434 BioGRID:130463 CCDC85C BioGRID PMID: 25468996
Biochemical Activity
BioGRID:107434 BioGRID:107332 CCNB1 BioGRID PMID: 34942119
Proximity Label-MS
BioGRID:107434 BioGRID:114581 CCNB2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115298 CCS BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:119968 CCSER2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115933 CCT8 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:117140 CD2AP BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:110420 CD99 BioGRID PMID: 25468996
Affinity Capture-Western
BioGRID:107434 BioGRID:107431 CDC27 BioGRID PMID: 22539978,20686030
Affinity Capture-Western; Reconstituted Complex
BioGRID:107434 BioGRID:107433 CDC42 BioGRID PMID: 18057010
Proximity Label-MS
BioGRID:107434 BioGRID:116308 CDC42EP1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:117115 CDC42EP4 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:123657 CDCA3 BioGRID PMID: 25468996
Affinity Capture-Western; Reconstituted Complex
BioGRID:107434 BioGRID:120446 CDCA8 BioGRID PMID: 32934012
Affinity Capture-Western; Co-purification; Reconstituted Complex
BioGRID:107434 BioGRID:107434 CDH1 BioGRID PMID: 10910767,10202138
Affinity Capture-Western; Co-purification
BioGRID:107434 BioGRID:107436 CDH3 BioGRID PMID: 10910767
Affinity Capture-MS
BioGRID:107434 BioGRID:107441 CDH8 BioGRID PMID: 33961781
Affinity Capture-MS
BioGRID:107434 BioGRID:132983 CDHR4 BioGRID PMID: 33961781
Affinity Capture-Western
BioGRID:107434 BioGRID:107454 CDK4 BioGRID PMID: 35525274
Affinity Capture-Western
BioGRID:107434 BioGRID:114376 CDK5R1 BioGRID PMID: 16029324
Affinity Capture-Western
BioGRID:107434 BioGRID:107456 CDK6 BioGRID PMID: 35525274
Two-hybrid
BioGRID:107434 BioGRID:107458 CDK8 BioGRID PMID: 24412244
Proximity Label-MS
BioGRID:107434 BioGRID:112668 CDKL5 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:117188 CEMIP2 BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:107506 CFTR BioGRID PMID: 26618866,17110338
Proximity Label-MS
BioGRID:107434 BioGRID:121589 CGN BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:107533 CHD4 BioGRID PMID: 35559673
Reconstituted Complex
BioGRID:107434 BioGRID:107536 CHEK1 BioGRID PMID: 34509474
Proximity Label-MS
BioGRID:107434 BioGRID:117462 CHMP2B BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:126170 CHMP4B BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:119579 CHMP5 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121328 CIAPIN1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121687 CIP2A BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115137 CKAP5 BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:107600 CLCN7 BioGRID PMID: 34591612
Affinity Capture-MS
BioGRID:107434 BioGRID:119158 CLEC4A BioGRID PMID: 33961781
Proximity Label-MS
BioGRID:107434 BioGRID:107604 CLIC1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115038 CLINT1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:122889 CLMN BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:107665 CNN2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:107666 CNN3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116511 COBLL1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:107704 COL17A1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:117926 COPG2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121425 CORO1B BioGRID PMID: 25468996
Affinity Capture-Western; Reconstituted Complex
BioGRID:107434 BioGRID:107777 CREBBP BioGRID PMID: 19114997,16319895
Proximity Label-MS
BioGRID:107434 BioGRID:107788 CRK BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:107789 CRKL BioGRID PMID: 25468996
Affinity Capture-Western
BioGRID:107434 BioGRID:107800 CRYAB BioGRID PMID: 22158051
Proximity Label-MS
BioGRID:107434 BioGRID:106705 CRYBG1 BioGRID PMID: 25468996
Affinity Capture-Western; Reconstituted Complex
BioGRID:107434 BioGRID:107821 CSE1L BioGRID PMID: 20734115,12061792
Affinity Capture-MS; Proximity Label-MS
BioGRID:107434 BioGRID:107836 CSNK1A1 BioGRID PMID: 27684187,25468996
Proximity Label-MS
BioGRID:107434 BioGRID:107837 CSNK1D BioGRID PMID: 25468996
Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Proximity Label-MS
BioGRID:107434 BioGRID:107876 CTNNA1 BioGRID PMID: 35831314,34591612,25468996,16212417,11960376,10381631,9233779,8227214,7542250
Affinity Capture-MS; Proximity Label-MS
BioGRID:107434 BioGRID:107877 CTNNA2 BioGRID PMID: 34591612,25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:118885 CTNNA3 BioGRID PMID: 33961781,28514442
Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-fractionation; Co-localization; FRET; Proximity Label-MS; Reconstituted Complex
BioGRID:107434 BioGRID:107880 CTNNB1 BioGRID PMID: 35831314,35271311,34591612,33961781,31286874,29789528,28966723,27684187,26707622,25468996,25466890,24798214,23180380,22850631,22752307,22715382,22375065,22158051,19223551,18593907,17909039,17220478,16574648,16212417,16125672,15023525,12830000,12640114,12169098,12061792,11960376,11712088,11348595,11254878,11245482,11113628,10772923,10381631,9819408,9535896,9405455,9233779,8227214,7954478,7876318,7542250
Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-localization; FRET; Proximity Label-MS; Reconstituted Complex; Two-hybrid
BioGRID:107434 BioGRID:107881 CTNND1 BioGRID PMID: 34591612,33961781,29207493,26707622,25468996,25466890,23180380,22850631,22752307,22715382,21670201,20371349,19711372,19114997,12707304,12640114,12427869,10409703,9535896,7876318,7651399,7542250
Proximity Label-MS
BioGRID:107434 BioGRID:107888 CTSB BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108332 CTTN BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:107905 CXADR BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116648 DAAM1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:127478 DAB2IP BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:107975 DAG1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:107995 DBN1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:118809 DBNL BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:117545 DCAF4 BioGRID PMID: 30945288
Negative Genetic
BioGRID:107434 BioGRID:124027 DDI2 BioGRID PMID: 35559673
Affinity Capture-Western
BioGRID:107434 BioGRID:107234 DDR1 BioGRID PMID: 20432435
Affinity Capture-Western
BioGRID:107434 BioGRID:110975 DDR2 BioGRID PMID: 20432435
Negative Genetic
BioGRID:107434 BioGRID:120592 DDX19A BioGRID PMID: 35559673
Affinity Capture-MS; Proximity Label-MS
BioGRID:107434 BioGRID:113649 DDX39B BioGRID PMID: 27684187,25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108020 DDX3X BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108022 DDX6 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:120799 DENND4C BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:120001 DHX29 BioGRID PMID: 25468996
Co-fractionation
BioGRID:107434 BioGRID:108073 DIAPH1 BioGRID PMID: 35831314
Proximity Label-MS
BioGRID:107434 BioGRID:123559 DIAPH3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108083 DLG1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114662 DLG5 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:109569 DNAJB1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116930 DOCK9 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108159 DSC3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108163 DSG2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:107135 DST BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:116246 DUS4L BioGRID PMID: 33961781
Proximity Label-MS
BioGRID:107434 BioGRID:108190 DVL3 BioGRID PMID: 25468996
Affinity Capture-Western
BioGRID:107434 BioGRID:108201 E2F1 BioGRID PMID: 20948288
Proximity Label-MS
BioGRID:107434 BioGRID:116166 EBNA1BP2 BioGRID PMID: 25468996
Affinity Capture-Western
BioGRID:107434 BioGRID:108223 ECT2 BioGRID PMID: 21886810
Proximity Label-MS
BioGRID:107434 BioGRID:108237 EEF1A1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108256 EEF1D BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108257 EEF1G BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108258 EEF2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:122597 EFHD2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116779 EFR3A BioGRID PMID: 25468996
Affinity Capture-MS; Affinity Capture-Western; Co-localization; PCA; Proximity Label-MS; Two-hybrid
BioGRID:107434 BioGRID:108276 EGFR BioGRID PMID: 25468996,25402006,25241761,24658140,24189400,10969083
Proximity Label-MS
BioGRID:107434 BioGRID:116893 EHBP1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:129015 EHBP1L1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116138 EHD1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:119054 EHD4 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:123822 EIF2A BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108287 EIF2S3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:109857 EIF3E BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108291 EIF4B BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108296 EIF4G1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108297 EIF4G2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:113297 EIF4H BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108298 EIF5 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108299 EIF5A BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:125356 ELFN2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:123927 ELMOD3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:117764 ELP4 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108325 EMD BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108338 ENO1 BioGRID PMID: 25468996
Affinity Capture-Western
BioGRID:107434 BioGRID:108347 EP300 BioGRID PMID: 16319895
Proximity Label-MS
BioGRID:107434 BioGRID:108349 EPB41 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108350 EPB41L1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116753 EPB41L3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:120044 EPB41L4B BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108288 EPHA2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116569 EPN2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:120369 EPN3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108374 EPS15 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121840 EPS15L1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:120218 EPS8L1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:122297 EPS8L2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108376 ERBB2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108377 ERBB3 BioGRID PMID: 25468996
Affinity Capture-MS; Proximity Label-MS
BioGRID:107434 BioGRID:120997 ERBIN BioGRID PMID: 34591612,25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116714 ERC1 BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:108404 ESR2 BioGRID PMID: 29509190
Proximity Label-MS
BioGRID:107434 BioGRID:116927 ESYT1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121556 ESYT2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108426 EVPL BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116464 EXOC3 BioGRID PMID: 25468996
Affinity Capture-Western; Proximity Label-MS
BioGRID:107434 BioGRID:113271 EZR BioGRID PMID: 25468996,10462524
Proximity Label-MS
BioGRID:107434 BioGRID:119153 F11R BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:123674 FAM110A BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:567837 FAM110C BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:127911 FAM171B BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:128805 FAM83B BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:130292 FAM83H BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:127622 FAM91A1 BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:108473 FANCC BioGRID PMID: 35559673
Negative Genetic
BioGRID:107434 BioGRID:108474 FANCD2 BioGRID PMID: 35559673
Negative Genetic
BioGRID:107434 BioGRID:108483 FANCF BioGRID PMID: 35559673
Reconstituted Complex
BioGRID:107434 BioGRID:115189 FARP2 BioGRID PMID: 35525274
Proximity Label-MS
BioGRID:107434 BioGRID:108488 FASN BioGRID PMID: 25468996
Reconstituted Complex
BioGRID:107434 BioGRID:108532 FER BioGRID PMID: 12640114
Proximity Label-MS
BioGRID:107434 BioGRID:120752 FERMT1 BioGRID PMID: 25468996
Co-localization; Reconstituted Complex
BioGRID:107434 BioGRID:108551 FGFR1 BioGRID PMID: 27371729,25241761
Proximity Label-MS
BioGRID:107434 BioGRID:108605 FLNA BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108606 FLNB BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115506 FLOT1 BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:117269 FLRT1 BioGRID PMID: 33961781
Proximity Label-MS
BioGRID:107434 BioGRID:131167 FMN1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:125355 FMNL2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:120222 FNBP1L BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116031 FRS2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112508 FSCN1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108773 FTH1 BioGRID PMID: 25468996
Affinity Capture-Western; Reconstituted Complex
BioGRID:107434 BioGRID:108810 FYN BioGRID PMID: 12640114
Proximity Label-MS
BioGRID:107434 BioGRID:108824 GAB1 BioGRID PMID: 25468996
Two-hybrid
BioGRID:107434 BioGRID:122816 GALNT12 BioGRID PMID: 24412244
Proximity Label-MS
BioGRID:107434 BioGRID:117568 GAPVD1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116181 GCN1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:126937 GCOM1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116775 GGA3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:117520 GIGYF2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115978 GIPC1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:119237 GLOD4 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:109022 GM2A BioGRID PMID: 25468996
Affinity Capture-Western
BioGRID:107434 BioGRID:119246 GMNN BioGRID PMID: 23695679
Reconstituted Complex
BioGRID:107434 BioGRID:109030 GNA12 BioGRID PMID: 11136230
Reconstituted Complex
BioGRID:107434 BioGRID:115914 GNA13 BioGRID PMID: 11136230
Proximity Label-MS
BioGRID:107434 BioGRID:109063 GOLGA2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:109064 GOLGA3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115275 GOLGA5 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:136421 GOLGA8B BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:109066 GOLGB1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:117479 GORASP2 BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:109067 GOT1 BioGRID PMID: 33961781
Affinity Capture-MS
BioGRID:107434 BioGRID:109079 GPC1 BioGRID PMID: 27576135
Negative Genetic
BioGRID:107434 BioGRID:123786 GPR61 BioGRID PMID: 35559673
Proximity Label-MS
BioGRID:107434 BioGRID:114514 GPRC5A BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:125349 GPRIN1 BioGRID PMID: 25468996
Co-localization
BioGRID:107434 BioGRID:109187 GSK3B BioGRID PMID: 25241761
Proximity Label-MS
BioGRID:107434 BioGRID:109190 GSPT1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114461 H1-10 BioGRID PMID: 25468996
Co-fractionation
BioGRID:107434 BioGRID:109263 H1-4 BioGRID PMID: 35831314
Co-localization; Proximity Label-MS
BioGRID:107434 BioGRID:113946 H3C1 BioGRID PMID: 29466696,25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:109280 HADHA BioGRID PMID: 34591612
Affinity Capture-MS
BioGRID:107434 BioGRID:109282 HADHB BioGRID PMID: 34591612
Proximity Label-MS
BioGRID:107434 BioGRID:109304 HCFC1 BioGRID PMID: 25468996
Affinity Capture-Western; Co-purification
BioGRID:107434 BioGRID:109315 HDAC1 BioGRID PMID: 15388328
Affinity Capture-Western; Co-localization; Co-purification
BioGRID:107434 BioGRID:109316 HDAC2 BioGRID PMID: 25241761,15388328
Proximity Label-MS
BioGRID:107434 BioGRID:109319 HDLBP BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:117359 HECTD1 BioGRID PMID: 29511261
Two-hybrid
BioGRID:107434 BioGRID:120641 HEMGN BioGRID PMID: 24412244
Proximity Label-MS
BioGRID:107434 BioGRID:109352 HLA-C BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:128670 HNRNPA3 BioGRID PMID: 35559673
Proximity Label-MS
BioGRID:107434 BioGRID:109431 HNRNPK BioGRID PMID: 25468996
Two-hybrid
BioGRID:107434 BioGRID:109501 HRAS BioGRID PMID: 24412244
Two-hybrid
BioGRID:107434 BioGRID:109526 HSD17B3 BioGRID PMID: 24412244
Affinity Capture-MS
BioGRID:107434 BioGRID:109552 HSP90AA1 BioGRID PMID: 16212417
Proximity Label-MS
BioGRID:107434 BioGRID:109558 HSP90AB1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:109535 HSPA1A BioGRID PMID: 25468996
Affinity Capture-MS; Proximity Label-MS
BioGRID:107434 BioGRID:109541 HSPA5 BioGRID PMID: 25468996,16212417
Affinity Capture-MS; Proximity Label-MS
BioGRID:107434 BioGRID:109544 HSPA8 BioGRID PMID: 27684187,25468996,16212417
Affinity Capture-MS
BioGRID:107434 BioGRID:109545 HSPA9 BioGRID PMID: 16212417
Negative Genetic
BioGRID:107434 BioGRID:118020 HSPB7 BioGRID PMID: 35559673
Affinity Capture-MS
BioGRID:107434 BioGRID:109561 HSPD1 BioGRID PMID: 16212417
Proximity Label-MS
BioGRID:107434 BioGRID:124188 HYCC1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:130030 HYCC2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:109643 IDH1 BioGRID PMID: 25468996
Affinity Capture-Western
BioGRID:107434 BioGRID:109644 IDH2 BioGRID PMID: 34271087
Proximity Label-MS
BioGRID:107434 BioGRID:109698 IGBP1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:109703 IGF2R BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:109714 IGHA1 BioGRID PMID: 16212417
Co-fractionation
BioGRID:107434 BioGRID:109819 IL18 BioGRID PMID: 35831314
Proximity Label-MS
BioGRID:107434 BioGRID:109786 IL6ST BioGRID PMID: 25468996
Co-fractionation
BioGRID:107434 BioGRID:109821 ILF2 BioGRID PMID: 35831314
Affinity Capture-MS
BioGRID:107434 BioGRID:109824 ILK BioGRID PMID: 25852190
Proximity Label-MS
BioGRID:107434 BioGRID:120883 INAVA BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:109848 INPPL1 BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:109842 INS BioGRID PMID: 32457219
Affinity Capture-Western; Proximity Label-MS; Reconstituted Complex
BioGRID:107434 BioGRID:114353 IQGAP1 BioGRID PMID: 25468996,10608854
Proximity Label-MS
BioGRID:107434 BioGRID:109863 IRAK1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115141 IST1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:119562 ISYNA1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:109864 ITGA6 BioGRID PMID: 25468996
Co-purification
BioGRID:107434 BioGRID:109888 ITGAE BioGRID PMID: 12434297
Proximity Label-MS
BioGRID:107434 BioGRID:109894 ITGB1 BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:109901 ITGB7 BioGRID PMID: 35559673
Proximity Label-MS
BioGRID:107434 BioGRID:112622 ITPRID2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:109917 IVL BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121655 JCAD BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:119338 JPT1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:124774 JPT2 BioGRID PMID: 25468996
Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Proximity Label-MS; Reconstituted Complex
BioGRID:107434 BioGRID:109931 JUP BioGRID PMID: 35831314,34591612,27684187,25468996,22375065,14517306,9535896,8207061,8074697,7542250,1639850
Proximity Label-MS
BioGRID:107434 BioGRID:117449 KANK2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:109984 KCNN4 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:126010 KDF1 BioGRID PMID: 25468996
Affinity Capture-Western; Proximity Label-MS; Reconstituted Complex
BioGRID:107434 BioGRID:115156 KEAP1 BioGRID PMID: 25468996,22302998
Proximity Label-MS
BioGRID:107434 BioGRID:121111 KIAA1217 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121685 KIAA1522 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:124506 KIAA1671 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121565 KIDINS220 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:110000 KIF5B BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:122313 KLC2 BioGRID PMID: 25468996
Affinity Capture-Western
BioGRID:107434 BioGRID:114726 KLF4 BioGRID PMID: 21177849
Affinity Capture-MS
BioGRID:107434 BioGRID:110043 KRAS BioGRID PMID: 27684187
Affinity Capture-MS
BioGRID:107434 BioGRID:110046 KRT1 BioGRID PMID: 16212417
Affinity Capture-MS; Proximity Label-MS
BioGRID:107434 BioGRID:110073 KRT18 BioGRID PMID: 25468996,16212417
Affinity Capture-MS
BioGRID:107434 BioGRID:110054 KRT8 BioGRID PMID: 16212417
Affinity Capture-MS
BioGRID:107434 BioGRID:110055 KRT9 BioGRID PMID: 16212417
Proximity Label-MS
BioGRID:107434 BioGRID:110092 KTN1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:110095 LAD1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116947 LARP1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:110120 LASP1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:110122 LBR BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:110131 LDHA BioGRID PMID: 25468996
Affinity Capture-Western
BioGRID:107434 BioGRID:110150 LGALS3BP BioGRID PMID: 29207493
Proximity Label-MS
BioGRID:107434 BioGRID:119559 LIMA1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116645 LIMCH1 BioGRID PMID: 25468996
Co-fractionation
BioGRID:107434 BioGRID:110176 LIPA BioGRID PMID: 35831314
Proximity Label-MS
BioGRID:107434 BioGRID:110183 LLGL1 BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:110186 LMNA BioGRID PMID: 16212417
Proximity Label-MS
BioGRID:107434 BioGRID:110193 LMO7 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:110208 LPP BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:127609 LRATD2 BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:115432 LRPPRC BioGRID PMID: 34591612
Proximity Label-MS
BioGRID:107434 BioGRID:129089 LRRC57 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:120649 LRRC59 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121610 LRRC7 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114642 LRRFIP1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:119629 LSR BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:113574 LUZP1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116444 LYPLA2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:124083 LZTS2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:4383846 M BioGRID PMID: 35337019
Proximity Label-MS
BioGRID:107434 BioGRID:131381 MACC1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:117048 MACF1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114927 MACROH2A1 BioGRID PMID: 25468996
Affinity Capture-Western; Reconstituted Complex
BioGRID:107434 BioGRID:115722 MAD2L2 BioGRID PMID: 32811646
Affinity Capture-Western; Proximity Label-MS
BioGRID:107434 BioGRID:114655 MAGI1 BioGRID PMID: 25468996,10772923
Proximity Label-MS
BioGRID:107434 BioGRID:129277 MAGI3 BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:110290 MAGOH BioGRID PMID: 35559673
Two-hybrid
BioGRID:107434 BioGRID:111590 MAP2K1 BioGRID PMID: 24412244
Proximity Label-MS
BioGRID:107434 BioGRID:110306 MAP4 BioGRID PMID: 25468996
Two-hybrid
BioGRID:107434 BioGRID:111581 MAPK3 BioGRID PMID: 24412244
Proximity Label-MS
BioGRID:107434 BioGRID:116581 MAPRE1 BioGRID PMID: 25468996
Affinity Capture-Western
BioGRID:107434 BioGRID:128666 MARCHF8 BioGRID PMID: 33540066
Proximity Label-MS
BioGRID:107434 BioGRID:110257 MARCKS BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:108326 MARK2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:110310 MARK3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:127502 MARVELD2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121570 MAVS BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:110319 MAX BioGRID PMID: 35559673
Proximity Label-MS
BioGRID:107434 BioGRID:127413 MB21D2 BioGRID PMID: 25468996
Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
BioGRID:107434 BioGRID:110358 MDM2 BioGRID PMID: 32805084,31337857,25086032,16980628
Affinity Capture-Western
BioGRID:107434 BioGRID:110391 MET BioGRID PMID: 11254878
Proximity Label-MS
BioGRID:107434 BioGRID:124504 MICALL1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:119075 MINK1 BioGRID PMID: 25468996
Biochemical Activity
BioGRID:107434 BioGRID:110434 MKI67 BioGRID PMID: 34942119
Proximity Label-MS
BioGRID:107434 BioGRID:126785 MPP7 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116776 MPRIP BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114486 MPZL1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:110501 MRE11 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121563 MRTFB BioGRID PMID: 25468996
Two-hybrid
BioGRID:107434 BioGRID:124810 MSANTD3 BioGRID PMID: 24412244
Proximity Label-MS
BioGRID:107434 BioGRID:110712 MYH9 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:110567 MYO1B BioGRID PMID: 25468996
Proximity Label-MS; Reconstituted Complex
BioGRID:107434 BioGRID:110730 MYO6 BioGRID PMID: 25468996,23007415
Affinity Capture-Western
BioGRID:107434 BioGRID:110731 MYO7A BioGRID PMID: 11080149
Biochemical Activity
BioGRID:107434 BioGRID:201430 Mki67 BioGRID PMID: 34942119
Proximity Label-MS
BioGRID:107434 BioGRID:115036 N4BP1 BioGRID PMID: 25468996
Two-hybrid
BioGRID:107434 BioGRID:119921 NANS BioGRID PMID: 24412244
Proximity Label-MS
BioGRID:107434 BioGRID:124606 NAV2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:110770 NCK1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114020 NCK2 BioGRID PMID: 25468996
Affinity Capture-Western; Co-fractionation; Proximity Label-MS
BioGRID:107434 BioGRID:115669 NDRG1 BioGRID PMID: 25468996,17786215,17220478
Proximity Label-MS
BioGRID:107434 BioGRID:121520 NDRG2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115784 NEBL BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111776 NECTIN1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111777 NECTIN2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:123544 NECTIN4 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:110844 NF2 BioGRID PMID: 25468996
Affinity Capture-Western; Reconstituted Complex
BioGRID:107434 BioGRID:110852 NFE2L2 BioGRID PMID: 22302998
Proximity Label-MS
BioGRID:107434 BioGRID:110861 NFKBIE BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:117466 NGDN BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114769 NHERF1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114754 NHERF2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:110875 NHS BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121460 NHSL1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:122328 NIBAN2 BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:114080 NIPSNAP1 BioGRID PMID: 16212417
Affinity Capture-MS
BioGRID:107434 BioGRID:108901 NIPSNAP2 BioGRID PMID: 16212417
Co-fractionation
BioGRID:107434 BioGRID:124517 NKD2 BioGRID PMID: 20177058
Proximity Label-MS
BioGRID:107434 BioGRID:120787 NLRP2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115783 NOP56 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:110913 NOTCH1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:110915 NOTCH2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:110916 NOTCH3 BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:114012 NR0B2 BioGRID PMID: 35559673
Affinity Capture-MS
BioGRID:107434 BioGRID:108375 NR2F6 BioGRID PMID: 33961781
Proximity Label-MS
BioGRID:107434 BioGRID:121014 NSFL1C BioGRID PMID: 25468996
Co-fractionation
BioGRID:107434 BioGRID:120236 NSUN2 BioGRID PMID: 35831314
Proximity Label-MS
BioGRID:107434 BioGRID:115950 NUDC BioGRID PMID: 25468996
Co-fractionation; Proximity Label-MS
BioGRID:107434 BioGRID:116335 NUDT5 BioGRID PMID: 35831314,25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114202 NUMB BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114677 NUMBL BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:113717 NUP214 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111004 OCLN BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:118917 OLA1 BioGRID PMID: 25468996
Affinity Capture-MS; Two-hybrid
BioGRID:107434 BioGRID:4383871 ORF7b BioGRID PMID: 36217030
Proximity Label-MS
BioGRID:107434 BioGRID:116413 PACSIN2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:120931 PAG1 BioGRID PMID: 25468996
Affinity Capture-Western
BioGRID:107434 BioGRID:111090 PAH BioGRID PMID: 33260674
Proximity Label-MS
BioGRID:107434 BioGRID:115852 PAICS BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111098 PAK2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115586 PAK4 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121251 PAK6 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116386 PALM2AKAP2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:131220 PALM3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121134 PARD3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116446 PARK7 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:120860 PARVA BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115502 PATJ BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111126 PCBP1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111127 PCBP2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111130 PCDH1 BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:111131 PCDHGC3 BioGRID PMID: 33961781,28514442
Proximity Label-MS
BioGRID:107434 BioGRID:111141 PCMT1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116461 PDAP1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114572 PDLIM1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115857 PDLIM5 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114682 PDLIM7 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116681 PDXDC1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:122926 PEAK1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111235 PFKP BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111237 PFN1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115693 PGRMC2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115097 PHACTR2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:122429 PHACTR4 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:124661 PHLDB2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111315 PI4KA BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:113902 PICALM BioGRID PMID: 25468996
Affinity Capture-Western; FRET
BioGRID:107434 BioGRID:116969 PIP5K1C BioGRID PMID: 22850631,22375065
Affinity Capture-Western
BioGRID:107434 BioGRID:111327 PKD1 BioGRID PMID: 21126580
Proximity Label-MS
BioGRID:107434 BioGRID:111332 PKM BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111572 PKN2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111335 PKP2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116357 PKP3 BioGRID PMID: 25468996
Affinity Capture-MS; Proximity Label-MS; Two-hybrid
BioGRID:107434 BioGRID:114074 PKP4 BioGRID PMID: 34591612,25468996,12615965
Proximity Label-MS
BioGRID:107434 BioGRID:111347 PLCB3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111355 PLEC BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121880 PLEKHA1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121881 PLEKHA2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:119982 PLEKHA5 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116541 PLEKHA6 BioGRID PMID: 25468996
Affinity Capture-MS; Proximity Label-MS
BioGRID:107434 BioGRID:126828 PLEKHA7 BioGRID PMID: 34591612,25468996
Proximity Label-MS
BioGRID:107434 BioGRID:123215 PLEKHO2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115520 PLIN3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111373 PLSCR1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121341 PLSCR3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:123048 POF1B BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:111430 POLR2E BioGRID PMID: 16212417
Proximity Label-MS
BioGRID:107434 BioGRID:114068 PPFIBP1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111488 PPL BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:119524 PPME1 BioGRID PMID: 25468996
Affinity Capture-Western; Proximity Label-MS
BioGRID:107434 BioGRID:111493 PPP1CA BioGRID PMID: 25468996,17274640
Proximity Label-MS
BioGRID:107434 BioGRID:116948 PPP1R13B BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116059 PPP1R13L BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:128092 PPP1R18 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:129838 PPP1R37 BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:120344 PPP2R3C BioGRID PMID: 35559673
Proximity Label-MS
BioGRID:107434 BioGRID:111089 PRDX1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114956 PRDX6 BioGRID PMID: 25468996
Co-fractionation
BioGRID:107434 BioGRID:111577 PRKDC BioGRID PMID: 35831314
Proximity Label-MS
BioGRID:107434 BioGRID:127318 PROM2 BioGRID PMID: 25468996
Affinity Capture-MS; Affinity Capture-Western
BioGRID:107434 BioGRID:111642 PSEN1 BioGRID PMID: 34591612,19114997,16126725,10635315
Proximity Label-MS
BioGRID:107434 BioGRID:111667 PSMB6 BioGRID PMID: 25468996
Affinity Capture-Western; Co-fractionation
BioGRID:107434 BioGRID:111719 PTK2 BioGRID PMID: 35831314,35525274
Proximity Label-MS
BioGRID:107434 BioGRID:111736 PTPN1 BioGRID PMID: 25468996
Affinity Capture-Western
BioGRID:107434 BioGRID:111753 PTPRD BioGRID PMID: 21126580
Affinity Capture-Western
BioGRID:107434 BioGRID:111757 PTPRG BioGRID PMID: 21126580
Proximity Label-MS
BioGRID:107434 BioGRID:111759 PTPRJ BioGRID PMID: 25468996
Affinity Capture-Western
BioGRID:107434 BioGRID:111761 PTPRM BioGRID PMID: 9531566
Affinity Capture-Western
BioGRID:107434 BioGRID:111766 PTPRS BioGRID PMID: 21126580
Biochemical Activity
BioGRID:107434 BioGRID:114663 PTTG1 BioGRID PMID: 34942119
Proximity Label-MS
BioGRID:107434 BioGRID:116502 PUF60 BioGRID PMID: 25468996
Co-fractionation; Proximity Label-MS
BioGRID:107434 BioGRID:111787 PXN BioGRID PMID: 35831314,25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116096 RAB10 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114661 RAB11B BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111799 RAB1A BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:121377 RAB25 BioGRID PMID: 35559673
Affinity Capture-Western
BioGRID:107434 BioGRID:119719 RAB8B BioGRID PMID: 12639940
Proximity Label-MS
BioGRID:107434 BioGRID:115671 RACK1 BioGRID PMID: 25468996
Affinity Capture-MS; Affinity Capture-Western
BioGRID:107434 BioGRID:111821 RAD17 BioGRID PMID: 20424596
Proximity Label-MS
BioGRID:107434 BioGRID:117526 RAI14 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111837 RAN BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111838 RANBP1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111840 RANGAP1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:122380 RAPH1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111852 RARS1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115160 RB1CC1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:111894 RDX BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:612841 RELL1 BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:106880 RHOA BioGRID PMID: 31980649
Negative Genetic
BioGRID:107434 BioGRID:125466 RMI2 BioGRID PMID: 35559673
Affinity Capture-MS
BioGRID:107434 BioGRID:111972 RNF2 BioGRID PMID: 24457600
Affinity Capture-Western; Biochemical Activity
BioGRID:107434 BioGRID:120241 RNF43 BioGRID PMID: 31286874
Co-fractionation
BioGRID:107434 BioGRID:112020 ROCK1 BioGRID PMID: 35831314
Co-fractionation
BioGRID:107434 BioGRID:114860 ROCK2 BioGRID PMID: 35831314
Proximity Label-MS
BioGRID:107434 BioGRID:114507 RPL14 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112058 RPL15 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112067 RPL23A BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112071 RPL24 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112078 RPL29 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112083 RPL34 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112092 RPL36A BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112085 RPL36AL BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112086 RPL37 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112048 RPL6 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112050 RPL7A BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112101 RPS2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112145 RPS26 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:117587 RSL1D1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121400 RTN4 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114166 RUVBL1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112190 S100A11 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112194 S100P BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:134996 SAPCD1 BioGRID PMID: 33961781
Proximity Label-MS
BioGRID:107434 BioGRID:131933 SBSN BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:107387 SCARB1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114324 SCEL BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:117060 SCRIB BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121512 SCYL1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:120810 SCYL2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112287 SDCBP BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115696 SEC24B BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:110812 SEPTIN2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:107425 SEPTIN7 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116015 SEPTIN9 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:117571 SERBP1 BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:112316 SET BioGRID PMID: 16212417
Proximity Label-MS
BioGRID:107434 BioGRID:109072 SFN BioGRID PMID: 25468996
Two-hybrid
BioGRID:107434 BioGRID:112321 SFRP2 BioGRID PMID: 24412244
Affinity Capture-MS
BioGRID:107434 BioGRID:112340 SGCA BioGRID PMID: 33961781
Affinity Capture-MS
BioGRID:107434 BioGRID:114398 SGPL1 BioGRID PMID: 34591612
Proximity Label-MS
BioGRID:107434 BioGRID:127448 SH3D19 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112352 SH3GL1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:119289 SH3GLB1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121234 SH3GLB2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:119029 SH3KBP1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:130149 SH3PXD2B BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121673 SH3RF1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116598 SHANK2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112358 SHB BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121665 SHROOM3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121723 SHTN1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116722 SIPA1L3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:126752 SIRPA BioGRID PMID: 25468996
Affinity Capture-Western
BioGRID:107434 BioGRID:119603 SIRT6 BioGRID PMID: 34244565
Affinity Capture-Western; Biochemical Activity
BioGRID:107434 BioGRID:112393 SKP2 BioGRID PMID: 26474281,20717963
Proximity Label-MS
BioGRID:107434 BioGRID:112447 SLC12A2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114571 SLC16A3 BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:112460 SLC18A3 BioGRID PMID: 35559673
Proximity Label-MS
BioGRID:107434 BioGRID:112401 SLC1A5 BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:116192 SLC27A4 BioGRID PMID: 34591612
Proximity Label-MS
BioGRID:107434 BioGRID:126837 SLC2A14 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:113560 SLC30A1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:123509 SLC38A1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112411 SLC3A2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114876 SLC4A7 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112438 SLC9A1 BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:123624 SLIRP BioGRID PMID: 33961781
Proximity Label-MS
BioGRID:107434 BioGRID:115096 SLK BioGRID PMID: 25468996
Co-fractionation
BioGRID:107434 BioGRID:110263 SMAD3 BioGRID PMID: 35831314
Affinity Capture-Western
BioGRID:107434 BioGRID:110267 SMAD7 BioGRID PMID: 18593713
Proximity Label-MS
BioGRID:107434 BioGRID:114303 SNAP23 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112500 SNAP25 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114748 SNAP29 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:117974 SND1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112525 SNX1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112526 SNX2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:118022 SNX5 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:119535 SNX9 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115831 SORBS1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112556 SPAG1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:124953 SPECC1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:127800 SPRED1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112585 SPRR3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112587 SPTAN1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112589 SPTBN1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112590 SPTBN2 BioGRID PMID: 25468996
Affinity Capture-Western; Proximity Label-MS
BioGRID:107434 BioGRID:112592 SRC BioGRID PMID: 31286874,25468996,21685945,18057010,10744074
Proximity Label-MS
BioGRID:107434 BioGRID:123275 SRCIN1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116956 SRGAP2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:120299 SSH3 BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:119039 ST6GALNAC6 BioGRID PMID: 33961781
Proximity Label-MS
BioGRID:107434 BioGRID:112649 STAT1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112650 STAT2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:120533 STEAP3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112662 STIM1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114011 STK24 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116457 STK38 BioGRID PMID: 25468996
Two-hybrid
BioGRID:107434 BioGRID:120346 STX17 BioGRID PMID: 24412244
Proximity Label-MS
BioGRID:107434 BioGRID:112679 STX4 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112680 STX5 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:118860 STXBP6 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112707 SVIL BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116707 SWAP70 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:125103 SYAP1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114388 SYNJ1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114391 SYNJ2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114525 SYT7 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:113995 TAGLN2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:124545 TANC1 BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:119061 TAX1BP3 BioGRID PMID: 33961781
Proximity Label-MS
BioGRID:107434 BioGRID:123787 TBC1D10A BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:117476 TBC1D10B BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:120772 TBC1D22B BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:120836 TENM3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:117572 TES BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:112898 TGFB1 BioGRID PMID: 27684187
Affinity Capture-MS
BioGRID:107434 BioGRID:112910 TGM2 BioGRID PMID: 16212417
Proximity Label-MS
BioGRID:107434 BioGRID:112937 TJP1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114809 TJP2 BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:112938 TK1 BioGRID PMID: 34591612
Co-fractionation; Proximity Label-MS
BioGRID:107434 BioGRID:112949 TLN1 BioGRID PMID: 35831314,25468996
Proximity Label-MS
BioGRID:107434 BioGRID:127028 TMEM199 BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:122780 TMEM204 BioGRID PMID: 35559673
Proximity Label-MS
BioGRID:107434 BioGRID:120404 TMEM51 BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:124010 TMEM79 BioGRID PMID: 35559673
Proximity Label-MS
BioGRID:107434 BioGRID:117453 TMEM87A BioGRID PMID: 25468996
Two-hybrid
BioGRID:107434 BioGRID:112966 TMOD1 BioGRID PMID: 24412244
Proximity Label-MS
BioGRID:107434 BioGRID:118899 TMOD3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:112967 TMPO BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:127753 TMTC2 BioGRID PMID: 34591612
Negative Genetic
BioGRID:107434 BioGRID:119478 TNFRSF12A BioGRID PMID: 35559673
Proximity Label-MS
BioGRID:107434 BioGRID:124540 TNKS1BP1 BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:113006 TOP2A BioGRID PMID: 35271311
Affinity Capture-MS
BioGRID:107434 BioGRID:120213 TOR4A BioGRID PMID: 34591612
Proximity Label-MS
BioGRID:107434 BioGRID:113012 TP53BP2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:113016 TPD52 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:113018 TPD52L2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:113500 TRIM25 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:117177 TRIM29 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114732 TRIP11 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:113056 TRIP6 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121455 TTC7A BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:113123 TTK BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:113124 TTN BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:128444 TUBB BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115656 TUBB4B BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:116462 TUSC2 BioGRID PMID: 35559673
Proximity Label-MS
BioGRID:107434 BioGRID:111723 TWF1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:116472 TWF2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115487 TXNDC9 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:120392 UACA BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:120938 UBAP2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:113164 UBC BioGRID PMID: 25468996
Co-crystal Structure
BioGRID:107434 BioGRID:116249 UBE2C BioGRID PMID: 34942119
Negative Genetic
BioGRID:107434 BioGRID:118858 UBE2T BioGRID PMID: 35559673
Proximity Label-MS
BioGRID:107434 BioGRID:121034 UBFD1 BioGRID PMID: 25468996
Affinity Capture-RNA; Affinity Capture-Western; Protein-RNA
BioGRID:107434 BioGRID:535038 UCA1 BioGRID PMID: 32805084
Biochemical Activity
BioGRID:107434 BioGRID:113194 UCHL3 BioGRID PMID: 24798214
Co-localization
BioGRID:107434 BioGRID:118893 UHRF1 BioGRID PMID: 29466696
Negative Genetic
BioGRID:107434 BioGRID:119697 UIMC1 BioGRID PMID: 35559673
Biochemical Activity
BioGRID:107434 BioGRID:1678070 UL97 BioGRID PMID: 20686030
Co-fractionation; Proximity Label-MS
BioGRID:107434 BioGRID:120986 UNC45A BioGRID PMID: 35831314,25468996
Co-fractionation
BioGRID:107434 BioGRID:111908 UPF1 BioGRID PMID: 35831314
Proximity Label-MS
BioGRID:107434 BioGRID:114173 USO1 BioGRID PMID: 25468996
Negative Genetic
BioGRID:107434 BioGRID:114551 USP14 BioGRID PMID: 35559673
Proximity Label-MS
BioGRID:107434 BioGRID:115283 USP15 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:125884 USP43 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115063 USP6NL BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114555 USP8 BioGRID PMID: 25468996
Co-fractionation
BioGRID:107434 BioGRID:113867 USP9X BioGRID PMID: 14742711
Proximity Label-MS
BioGRID:107434 BioGRID:113245 UTRN BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114747 VAMP3 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114651 VAPA BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:114650 VAPB BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:125406 VASN BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:113251 VASP BioGRID PMID: 25468996
Affinity Capture-Western; Co-fractionation; Proximity Label-MS
BioGRID:107434 BioGRID:113257 VCL BioGRID PMID: 35831314,25468996,9535896,9405455
Proximity Label-MS
BioGRID:107434 BioGRID:123125 VCPIP1 BioGRID PMID: 25468996
Affinity Capture-Western
BioGRID:107434 BioGRID:120736 VEZT BioGRID PMID: 11080149
Negative Genetic
BioGRID:107434 BioGRID:126479 VPS37A BioGRID PMID: 35559673
Proximity Label-MS
BioGRID:107434 BioGRID:127065 VSIG10L BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115465 WASF2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:127043 WIPF2 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:119707 WWOX BioGRID PMID: 25468996
Affinity Capture-MS
BioGRID:107434 BioGRID:113353 XRCC5 BioGRID PMID: 16212417
Proximity Label-MS
BioGRID:107434 BioGRID:119970 XRN1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115684 YAP1 BioGRID PMID: 25468996
Reconstituted Complex
BioGRID:107434 BioGRID:113357 YES1 BioGRID PMID: 12640114
Proximity Label-MS
BioGRID:107434 BioGRID:115895 YKT6 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:113361 YWHAB BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:113363 YWHAE BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:113366 YWHAZ BioGRID PMID: 25468996
Co-fractionation
BioGRID:107434 BioGRID:119290 ZC2HC1A BioGRID PMID: 35831314
Proximity Label-MS
BioGRID:107434 BioGRID:120956 ZC3H15 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:121203 ZC3HAV1 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:117422 ZDHHC5 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:115111 ZFYVE16 BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:125855 ZG16B BioGRID PMID: 25468996
Proximity Label-MS
BioGRID:107434 BioGRID:113525 ZNF185 BioGRID PMID: 25468996
Two-hybrid
BioGRID:107434 BioGRID:116536 ZNF510 BioGRID PMID: 24412244
Proximity Label-MS
BioGRID:107434 BioGRID:113569 ZYX BioGRID PMID: 25468996
GENERAL GENE INFO
-------------------------------------------------------------------------------------------------
Marker
D11S2921 (e-PCR) Links:UniSTS:152074
PMC84611P1 (e-PCR) Links:UniSTS:273449
GDB:361044 (e-PCR) Links:UniSTS:156724
GDB:361074 (e-PCR) Links:UniSTS:156725
GDB:361084 (e-PCR) Links:UniSTS:156726
GDB:361089 (e-PCR) Links:UniSTS:156727
GDB:361093 (e-PCR) Links:UniSTS:156728
GDB:361098 (e-PCR) Links:UniSTS:156729
GDB:361103 (e-PCR) Links:UniSTS:156730
GDB:361109 (e-PCR) Links:UniSTS:156731
GDB:361113 (e-PCR) Links:UniSTS:156732
SHGC-33499 (e-PCR) Links:UniSTS:23613
GDB:361120 (e-PCR) Links:UniSTS:156733
GDB:361125 (e-PCR) Links:UniSTS:156734
GDB:361128 (e-PCR) Links:UniSTS:156735
GDB:361131 (e-PCR) Links:UniSTS:156736
Cdh1 (e-PCR), detects polymorphism Links:UniSTS:472904
RH64967 (e-PCR) Links:UniSTS:89433
CDH1_96.2 (e-PCR) Links:UniSTS:277087
D1S1423 (e-PCR) Links:UniSTS:149619
RH68244 (e-PCR) Links:UniSTS:1912
RH64971 (e-PCR) Links:UniSTS:91522
STS-T85105 (e-PCR) Links:UniSTS:9091
RH91417 (e-PCR) Links:UniSTS:88196
PMC134726P1 (e-PCR) Links:UniSTS:270747
A008N17 (e-PCR) Links:UniSTS:11680
PMC135805P1 (e-PCR) Links:UniSTS:270774
PMC135805P2 (e-PCR) Links:UniSTS:270775
PMC135805P3 (e-PCR) Links:UniSTS:270776
PMC135805P4 (e-PCR) Links:UniSTS:270777
PMC135805P5 (e-PCR) Links:UniSTS:270778
RH65826 (e-PCR) Links:UniSTS:19434
SHGC-149254 (e-PCR) Links:UniSTS:176889
Homology
Homologs of the CDH1 gene
The CDH1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.
Orthologs from Annotation Pipeline (/gene/?Term=ortholog_gene_999[group]):
Orthologs
Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
Function GO ID Evidence
-------------------------------------------------------------------------------------------------
enables GTPase activating protein bindin... GO:0000000 PMID: 20116244
enables ankyrin binding GO:0000000 PMID: 17620337
enables beta-catenin binding GO:0000000 PMID: 17620337
enables cadherin binding GO:0000000 PMID: 25468996
enables cadherin binding GO:0000000 PMID: 21873635
enables calcium ion binding GO:0000000 PMID: 21873635
enables cell adhesion molecule binding GO:0000000 PMID: 21724833
enables cell adhesion molecule binding GO:0000000 PMID: 16338932
enables gamma-catenin binding GO:0000000 PMID: 1639850
enables identical protein binding GO:0000000 PMID: 19114658,19646884,21300292,23112161,24725409
enables protein binding GO:0000000 PMID: 10725230,11401320,11790773,12526809,15695390,16212417,16983094,17220478,17274640,17715295,18093941,18593713,19016843,19038973,19732724,19822757,20086044,21685945,22056988,22158051,22252131,22750944,23086448,24189400,24424122,24658140,25241761,25344754,31473225,31980649,32814053,34591612
enables protein tyrosine kinase binding GO:0000000 -
Processs GO ID Evidence
-------------------------------------------------------------------------------------------------
involved_in adherens junction organizati... GO:0000000 PMID: 21873635
involved_in adherens junction organizati... GO:0000000 PMID: 21724833
involved_in calcium-dependent cell-cell ... GO:0000000 PMID: 21873635
involved_in cell morphogenesis GO:0000000 PMID: 21873635
involved_in cell-cell adhesion GO:0000000 PMID: 16338932,18593713
involved_in cell-cell adhesion mediated ... GO:0000000 PMID: 21873635
involved_in cell-cell junction assembly GO:0000000 PMID: 21873635
involved_in cellular response to indole-... GO:0000000 PMID: 10868478
involved_in cellular response to lithium... GO:0000000 PMID: 12937339
involved_in homophilic cell adhesion via... GO:0000000 PMID: 8033105,16338932
involved_in multicellular organism devel... GO:0000000 PMID: 21873635
involved_in negative regulation of axon ... GO:0000000 -
involved_in negative regulation of cell ... GO:0000000 PMID: 16882694
involved_in negative regulation of cell-... GO:0000000 PMID: 19653274
involved_in neuron projection developmen... GO:0000000 -
involved_in pituitary gland development GO:0000000 -
involved_in positive regulation of DNA-t... GO:0000000 PMID: 16338932
involved_in positive regulation of prote... GO:0000000 PMID: 16338932
involved_in protein localization to plas... GO:0000000 PMID: 17620337
involved_in protein localization to plas... GO:0000000 PMID: 20859650
involved_in regulation of gene expressio... GO:0000000 PMID: 19403558
involved_in regulation of protein catabo... GO:0000000 -
involved_in response to Gram-positive ba... GO:0000000 -
involved_in response to toxic substance GO:0000000 -
involved_in response to xenobiotic stimu... GO:0000000 -
involved_in synapse assembly GO:0000000 PMID: 21873635
Component GO ID Evidence
-------------------------------------------------------------------------------------------------
located_in actin cytoskeleton GO:0000000 PMID: 16338932
is_active_in adherens junction GO:0000000 PMID: 21873635
located_in adherens junction GO:0000000 PMID: 16338932,20086044,24046456
located_in apical junction complex GO:0000000 PMID: 10460003
part_of catenin complex GO:0000000 PMID: 21873635
part_of catenin complex GO:0000000 PMID: 18593713
located_in cell junction GO:0000000 PMID: 19038973,28169360
located_in cell junction GO:0000000 PMID: 17047063
colocalizes_with cortical actin cytoskel... GO:0000000 PMID: 24046456
located_in cytoplasmic side of plasma me... GO:0000000 PMID: 20189993
located_in endosome GO:0000000 -
located_in extracellular exosome GO:0000000 PMID: 23533145
located_in extracellular region GO:0000000 -
part_of flotillin complex GO:0000000 PMID: 24046456
located_in glutamatergic synapse GO:0000000 -
located_in lamellipodium GO:0000000 PMID: 24046456
located_in lateral plasma membrane GO:0000000 PMID: 16338932,17620337
located_in membrane GO:0000000 PMID: 16338932
located_in perinuclear region of cytopla... GO:0000000 PMID: 16338932
located_in plasma membrane GO:0000000 PMID: 28301459
located_in plasma membrane GO:0000000 -
located_in postsynapse GO:0000000 -
located_in trans-Golgi network GO:0000000 PMID: 17620337
GENERAL PROTEIN INFORMATION
-------------------------------------------------------------------------------------------------
Preferred Names
cadherin-1
Names
CAM 120/80
E-cadherin 1
cadherin 1, E-cadherin (epithelial)
cadherin 1, type 1, E-cadherin (epithelial)
calcium-dependent adhesion protein, epithelial
cell-CAM 120/80
epididymis secretory sperm binding protein
epithelial cadherin
uvomorulin
NCBI REFERENCE SEQUENCES (RefSeq)
-------------------------------------------------------------------------------------------------
RefSeqs maintained independently of Annotated Genomes
These reference sequences exist independently of genome builds.
These reference sequences are curated independently of the genome annotation cycle,
so their versions may not match the RefSeq versions in the current genome build.
Identify version mismatches by comparing the version of the RefSeq in this section to
the one reported in Genomic regions, transcripts, and products section above.
Genomic
NG_008021.1 RefSeqGene
Range 5000..103249
Download GenBank FASTA Sequence Viewer (Graphics)
mRNA and Protein(s)
NM_001317184.2 → NP_001304113.1 REVIEWEDcadherin-1 isoform 2 precursor
Description: Transcript Variant: This variant (2) lacks an a...
Source sequence(s): AB025105, AK312551, EU709494
Consensus CDS: CCDS82005.1
UniProtKB/TrEMBL: B3GN61
UniProtKB/Swiss-Prot: P12830
Related Ensembl: ENSP00000414946.2, ENST00000422392.6
Conserved Domains (5)summary
cd00031:
Location:158 - 258
CA_like; Cadherin repeat-like domain
cd11304:
Location:431 - 530
Cadherin_repeat; Cadherin tandem repeat domain
pfam00028:
Location:537 - 625
Cadherin; Cadherin domain
pfam01049:
Location:680 - 816
Cadherin_C; Cadherin cytoplasmic region
pfam08758:
Location:27 - 116
Cadherin_pro; Cadherin prodomain like
NM_001317185.2 → NP_001304114.1 REVIEWEDcadherin-1 isoform 3
Description: Transcript Variant: This variant (3) uses an al...
Source sequence(s): AB025106, AC099314, AK312551, EU709494
UniProtKB/TrEMBL: B3GN61
UniProtKB/Swiss-Prot: P12830
UniProtKB/TrEMBL: Q9UII7
Conserved Domains (3)summary
cd11304:
Location:3 - 75
Cadherin_repeat; Cadherin tandem repeat domain
pfam00028:
Location:82 - 170
Cadherin; Cadherin domain
pfam01049:
Location:225 - 361
Cadherin_C; Cadherin cytoplasmic region
NM_001317186.2 → NP_001304115.1 REVIEWEDcadherin-1 isoform 4
Description: Transcript Variant: This variant (4) lacks an e...
Source sequence(s): AK312551, BC144283, EU709494
UniProtKB/TrEMBL: B3GN61
UniProtKB/Swiss-Prot: P12830
Conserved Domains (1)summary
pfam01049:
Location:83 - 224
Cadherin_C; Cadherin cytoplasmic region
NM_004360.5 → NP_004351.1 REVIEWEDcadherin-1 isoform 1 preproprotein
See proteins identical to NP_004351.1 at http://130.14.22.106/ipg/NP_004351.1/
Description: Transcript Variant: This variant (1) encodes th...
Source sequence(s): AK290012, AK312551, EU709494
Consensus CDS: CCDS10869.1
UniProtKB/TrEMBL: A0A0U2ZQU7
UniProtKB/TrEMBL: B3GN61
UniProtKB/Swiss-Prot: P12830
UniProtKB/Swiss-Prot: Q9UII8
Related Ensembl: ENSP00000261769.4, ENST00000261769.10
Conserved Domains (5)summary
cd00031:
Location:158 - 258
CA_like; Cadherin repeat-like domain
cd11304:
Location:492 - 591
Cadherin_repeat; Cadherin tandem repeat domain
pfam01049:
Location:738 - 879
Cadherin_C; Cadherin cytoplasmic region
pfam08758:
Location:27 - 116
Cadherin_pro; Cadherin prodomain like
cl09101:
Location:598 - 686
E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either th...
RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_03
The following sections contain reference sequences that belong to a specific genome build.
This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which
this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both
reference and alternate assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
NC_000016.10 Reference GRCh38.p14 Primary Assembly
Range 68737291..68835536
Download GenBank FASTA Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
NC_060940.1 Alternate T2T-CHM13v2.0
Range 74533466..74631803
Download GenBank FASTA Sequence Viewer (Graphics)
RELATED SEQUENCES
-------------------------------------------------------------------------------------------------
Nucleotide Protein
-------------------------------------------------------------------------------------------------
genomic AC099314.3(177204..179065) None
genomic AH003504.2 None
genomic AH006175.2 None
genomic AH007361.2 AAD14108.1
genomic AY341818.1 None
genomic CH471092.1 EAW83242.1
EAW83243
EAW83244
EAW83245
genomic CP068262.2(74533467..74631804) None
genomic D49685.1 BAA08537.1
genomic DQ090940.1 AAY68225.1
genomic DQ335132.1 None
genomic GU371438.1 ADC53120.1
genomic JC597161.1 CEF39405.1
genomic KP232928.1 AKC34897.1
genomic KT355487.1 ALS87660.1
genomic KT820428.1 AMO26215.1
genomic KX271351.1 None
genomic L34545.1 AAA21764.1
genomic LC750329.1 BDW80550.1
genomic LC750330.1 BDW80551.1
genomic LC750331.1 BDW80552.1
genomic LC750332.1 BDW80553.1
genomic LC750333.1 BDW80554.1
genomic LC750334.1 BDW80555.1
genomic LC750335.1 BDW80556.1
genomic LC750336.1 BDW80557.1
genomic LC750337.1 BDW80558.1
genomic LC750338.1 BDW80559.1
genomic LC750339.1 BDW80560.1
genomic MG660829.1 AYN44076.1
genomic MK503194.1 None
genomic MN080224.1 QHW05978.1
genomic Z35402.1 CAA84586.1
genomic Z35403.1(15..158) None
genomic Z35404.1(15..170) None
genomic Z35405.1(15..159) None
genomic Z35406.1(15..190) None
genomic Z35407.1(15..143) None
genomic Z35408.1(15..197) None
genomic Z35409.1(15..259) None
genomic Z35410.1(15..160) None
genomic Z35411.1(15..239) None
genomic Z35412.1(15..242) None
genomic Z35413.1(15..145) None
genomic Z35414.1(15..158) None
genomic Z35415.1(15..2259) None
mRNA AB025105.1 BAA88956.1
mRNA AB025106.1 BAA88957.1
mRNA AI890107.1 None
mRNA AK290012.1 BAF82701.1
mRNA AK297913.1 BAG60232.1
mRNA AK309703.1 None
mRNA AK311198.1 None
mRNA AK312551.1 BAG35448.1
mRNA BC013851.1 None
mRNA BC141838.1 AAI41839.1
mRNA BC144283.1 None
mRNA BC146662.1 AAI46663.1
mRNA EU709494.1 ACD87624.1
mRNA GQ891411.1 ADO22273.1
mRNA L08599.1 AAA61259.1
mRNA MZ047303.1 UIW38054.1
mRNA X12790.1 CAA31279.1
mRNA X52279.1 CAA36522.1
mRNA Z13009.1 CAA78353.1
mRNA Z18923.1 CAA79356.1
Protein Accession Links
-------------------------------------------------------------------------------------------------
P12830.3 GenPept(/protein/399166) UniProtKB/Swiss-Prot:P12830
GENE LINKOUT
-------------------------------------------------------------------------------------------------
The following LinkOut(www.ncbi.nlm.nih.gov/projects/linkout/index.html) resources
are supplied by external providers. These providers are responsible for
maintaining the links.
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(Free resource) (free) PhosphoSitePlus
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GeneCard for CDH1GeneCard for CDH1
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Human cDNA clones used in NEDO Project / AK297913Human cDNA clones used in NEDO Project / AK297913Human cDNA clones used in NEDO Project / AK309703Human cDNA clones used in NEDO Project / AK309703Human cDNA clones used in NEDO Project / AK311198Human cDNA clones used in NEDO Project / AK311198
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Tools
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