--- a +++ b/GeneID_999.txt @@ -0,0 +1,2124 @@ +CDH1 cadherin 1[Homo sapiens] +Gene ID: 999, updated on 29-Mar-2023 + + +SUMMARY +------------------------------------------------------------------------------------------------- + +Official Symbol: CDH1 (provided by HGNC) +Official full name: cadherin 1 (provided by HGNC) +Primary source: HGNC:HGNC:1748 +See related: Ensembl:ENSG00000039068; MIM:192090; AllianceGenome:HGNC:1748 +Gene type: protein coding +RefSeq status: REVIEWED +Organism: Homo sapiens + +Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; +Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo + +Also known as: UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324 + +Summary: This gene encodes a classical cadherin of the cadherin superfamily. Alternative +splicing results in multiple transcript variants, at least one of which encodes a +preproprotein that is proteolytically processed to generate the mature +glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of +five extracellular cadherin repeats, a transmembrane region and a highly +conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, +breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is +thought to contribute to cancer progression by increasing proliferation, +invasion, and/or metastasis. The ectodomain of this protein mediates bacterial +adhesion to mammalian cells and the cytoplasmic domain is required for +internalization. This gene is present in a gene cluster with other members of the +cadherin family on chromosome 16. [provided by RefSeq, Nov 2015] + +Annotation information: Note: CDH1 (GeneID 999) and FZR1 (GeneID 51343) share the CDH1 symbol. CDH1 is +sometimes used as an abbreviation for 'CDC20 homolog 1' which is an alternate +name for the FZR1 gene and thus can be confused with the official symbol for +cadherin 1 (CDH1). [16 Jul 2018] + +Orthologsall (/gene/?Term=ortholog_gene_999[group]), mouse (https://www.ncbi.nlm.nih.gov/gene/12550) + +GENOMIC CONTEXT +------------------------------------------------------------------------------------------------- + + +Location: 16q22.1 + +Annotation release Status Assembly Chromosome Location +------------------------------------------------------------------------------------------------- +RS_2023_03 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (68737292..68835537) +RS_2023_03 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (74533467..74631804) +105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (68771195..68869440) +Exont count: 16 + + +BIBLIOGRAPHY +------------------------------------------------------------------------------------------------- + + +Related Articles in PubMed + +1. [Influence of E-cadherin methylation on prognosis in children with acute +lymphoblastic leukemia]. Qi FQ, . Zhongguo Dang Dai Er Ke Za Zhi, 2023 Jan 15, +PMID 36655663., Free PMC Article(s): PMC9893830 +2. Low expression of E-Cadherin and CDH1 variants associated with diffuse gastric +cancer. García-Ruvalcaba A, . Rev Invest Clin, 2023 Feb 20, PMID 36652613. +3. Soluble E-cadherin: A marker of genital epithelial disruption. Liu R, . Am J +Reprod Immunol, 2023 Mar, PMID 36593681. +4. The Identification of Large Rearrangements Involving Intron 2 of the CDH1 Gene in +BRCA1/2 Negative and Breast Cancer Susceptibility. Ben Aissa-Haj J, . Genes +(Basel), 2022 Nov 25, PMID 36553480., Free PMC Article(s): PMC9778491 +5. Clinical and prognostic features of E-cadherin in adenocarcinoma of the +esophagogastric junction patients. Hu K, . Eur J Cancer Prev, 2023 Mar 1, PMID +36484275. +6. Soluble E-cadherin promotes invasiveness of neoplastic cells in salivary gland +carcinoma ex pleomorphic adenoma. Chen W, . J Oral Pathol Med, 2023 Jan, PMID +36445289. +<pre> +PHENOTYPES +------------------------------------------------------------------------------------------------- + +Review eQTL and phenotype association data in this region using PheGenI + http://www.ncbi.nlm.nih.gov/gap/PheGenI?chr=16&from=68737291&fromto=68737291+68835536&tab=0 + +Associated conditions +------------------------------------------------------------------------------------------------- +Description Tests +------------------------------------------------------------------------------------------------- + +Blepharocheilodontic syndrome 1 + MedGen: C4551988 OMIM: 119580 GeneReviews: <span>Not available</span> +Endometrial carcinoma + MedGen: C0476089 OMIM: 608089 GeneReviews: <span>Not available</span> +Familial cancer of breast + MedGen: C0346153 OMIM: 114480 GeneReviews: BRCA1- and BRCA2-Associated Hereditary Breast and Ovarian Cancer +Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. + GeneReviews: <span>Not available</span> +Hereditary diffuse gastric adenocarcinoma + MedGen: C1708349 OMIM: 137215 GeneReviews: Hereditary Diffuse Gastric Cancer +Malignant tumor of prostate + MedGen: C0376358 OMIM: 176807 GeneReviews: <span>Not available</span> +Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. + GeneReviews: <span>Not available</span> +Neoplasm of ovary + MedGen: C0919267 OMIM: 167000 GeneReviews: <span>Not available</span> + +Copy number response +------------------------------------------------------------------------------------------------- +Copy number response + Triplosensitivity + No evidence available (Last evaluated 2020-04-10) + + ClinGen Genome Curation Page(https://www.ncbi.nlm.nih.gov/projects/dbvar/ISCA/isca_gene.cgi?sym=CDH1)Haploinsufficency + Sufficient evidence for dosage pathogenicity (Last evaluated 2020-04-10) + + ClinGen Genome Curation Page(https://www.ncbi.nlm.nih.gov/projects/dbvar/ISCA/isca_gene.cgi?sym=CDH1) + PubMed(/pubmed/19168852,24037103,26182300)</pre> + +VARIATION +------------------------------------------------------------------------------------------------- + +See variants in ClinVar, http://130.14.22.106/sites/gene/clinvar/?term=CDH1[gene] +See studies and variants in dbVar, http://130.14.22.106/sites/gene +See Variation Viewer (GRCh37.p13), http://130.14.22.106/sites/gene/variation/view/?q=999[geneid]&assm=GCF_000001405.25 +See Variation Viewer (GRCh38), http://130.14.22.106/sites/gene/variation/view/?q=999[geneid]<pre/><pre> +Genotypes + See SNP Geneview Report, http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2FSNP%2Fsnp_ref.cgi%3FlocusId%3D999 + See 1000 Genomes Browser (GCF_000001405.25), http://130.14.22.106/sites/gene/variation/tools/1000genomes/?q=999[geneid]&assm=GCF_000001405.25</pre> + +HIV-1 INTERACTIONS +------------------------------------------------------------------------------------------------- +Protein interactions +Protein Gene Interaction Pubs +------------------------------------------------------------------------------------------------- +/protein/28876544 /gene/155971 HIV-1 gp120 inhibits the expression of E-cadherin and changes its localization from cell membrane to cytoplasm in polarized oral epithelial cells 24586397 +/protein/9629358 /gene/155871 HIV-1 Tat C treated human brain microvascular endothelial cells result in downregulation and dissociation of VE-PTP and SHP2 from VE-cadherin 24965120 +/protein/9629358 /gene/155871 HIV-1 Tat C induces phosphorylation of adherens junction proteins VE-cadherin and beta-catenin in human brain microvascular endothelial cells 24965120 +/protein/9629358 /gene/155871 HIV-1 Tat inhibits the expression of E-cadherin and changes its localization from cell membrane to cytoplasm in polarized oral epithelial cells 24586397 +/protein/28872817 /gene/155807 HIV-1 Vpr-expressing Jurkat T cell clones showed upregulated expression of cadherin, suggesting a role of Vpr in modulating the cell adhesion process 10713718 +/protein/9629366 /gene/155945 HIV-1 Vpu reduces the beta-catenin interaction with E-cadherin and the Vpu-mediated dissociation of beta-catenin with E-cadherin enhances particle release 18256147 + +Go to the HIV-1, Human Interaction Database: http://130.14.22.106/genome/viruses/retroviruses/hiv-1/interactions/ + +INTERACTION +------------------------------------------------------------------------------------------------- + +Description of Gene Interaction table + +Product Interactant Other Gene Complex Source Pubs +------------------------------------------------------------------------------------------------- + +TCF8 (deltaEF1) interacts with the CDH1 (E-cadherin) promoter. +NC_000016.8 NP_110378.2 ZEB1 BIND PMID: 15674322 +E-cadherin interacts with caveolin-1. +NP_004351.1 NP_001744.2 CAV1 BIND PMID: 14706341 +Beta-catenin interacts with E-cadherin. This interaction was modelled on a demonstrated interaction between beta-catenin from an unspecified species and human E-cadherin. +NP_004351.1 NP_001895.1 CTNNB1 BIND PMID: 15542433 +Beta-catenin interacts with E-cadherin. This interaction was modelled on a demonstrated interaction between human beta-catenin and mouse E-cadherin. +NP_004351.1 NP_001895.1 CTNNB1 BIND PMID: 15294866 +E-cadherin interacts with beta-catenin. +NP_004351.1 NP_001895.1 CTNNB1 BIND PMID: 14706341 +CDH1(Ecad) interacts with P120ctn 3AC. This interaction was modelled on a demonstrated interaction between mouse CDH1(Ecad) and human P120ctn 3AC. +NP_004351.1 AAC39822.1 CTNND1 BIND PMID: 12707304 +EGFR interacts with E-cadherin +NP_004351.1 NP_005219.2 EGFR BIND PMID: 14681060 +P12830 P61158 ACTR3 HPRD PMID: 11882288 +P12830 Q9UJX3 ANAPC7 HPRD PMID: 12956947 +P12830 RICS ARHGAP32 HPRD PMID: 12531901 +P12830 O00192 ARVCF HPRD PMID: 11058098 +P12830 Q16790 CA9 HPRD PMID: 14567991 +P12830 P42574 CASP3 HPRD PMID: 11076937 +P12830 Q14790 CASP8 HPRD PMID: 12189238 +P12830 E cadherin binding protein E7 CBLL1 HPRD PMID: 11836526 +P12830 P12830 CDH1 HPRD PMID: 10202138 +P12830 P55060 CSE1L HPRD PMID: 12061792 +P12830 P68400 CSNK2A1 HPRD PMID: 10671552 +P12830 P35221 CTNNA1 HPRD PMID: 11226248,7542250 +P12830 P35222 CTNNB1 HPRD PMID: 17220478,17057644,11245482,11226248,9512503,7954478,7542250 +P12830 O60716 CTNND1 HPRD PMID: 11226248,10931041,10629228,10409703,10225956,7651399,7542250 +P12830 Q9UQB3 CTNND2 HPRD PMID: 9971746 +P12830 P00533 EGFR HPRD PMID: 10969083 +P12830 Q96RT1 ERBIN HPRD PMID: 11821434 +P12830 P15311 EZR HPRD PMID: 10462524 +P12830 Q03113 GNA12 HPRD PMID: 11136230 +P12830 Q14344 GNA13 HPRD PMID: 11136230 +P12830 P49841 GSK3B HPRD PMID: 10671552 +P12830 Q13547 HDAC1 HPRD PMID: 15388328 +P12830 Q92769 HDAC2 HPRD PMID: 15388328 +P12830 P46940 IQGAP1 HPRD PMID: 10608854 +P12830 P35568 IRS1 HPRD PMID: 11035789 +P12830 P38570 ITGAE HPRD PMID: 12434297 +P12830 P26010 ITGB7 HPRD PMID: 10837471 +P12830 P14923 JUP HPRD PMID: 11226248,10959047,8207061,8074697,7890674,7542250,1639850 +P12830 Q92597 NDRG1 HPRD PMID: 17220478 +P12830 P98161 PKD1 HPRD PMID: 11274246 +P12830 P62136 PPP1CA HPRD PMID: 17274640 +P12830 P49768 PSEN1 HPRD PMID: 11953314,11226248,10635315 +P12830 Q15678 PTPN14 HPRD PMID: 12808048 +P12830 P10586 PTPRF HPRD PMID: 12095414 +P12830 P28827 PTPRM HPRD PMID: 15588985,9531566,7642713 +P12830 Q92930 RAB8B HPRD PMID: 12639940 +P12830 P31350 RRM2 HPRD PMID: 12655059 +P12830 P18206 VCL HPRD PMID: 9405455 +Proximity Label-MS +BioGRID:107434 BioGRID:116520 AAK1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:120605 ABCF3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115324 ABI1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:110171 ABLIM1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116552 ABLIM3 BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:106555 ACADVL BioGRID PMID: 16212417 +Proximity Label-MS +BioGRID:107434 BioGRID:122262 ACBD3 BioGRID PMID: 25468996 +Affinity Capture-Western +BioGRID:107434 BioGRID:106586 ACTG1 BioGRID PMID: 9535896 +Affinity Capture-Western; 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Proximity Label-MS +BioGRID:107434 BioGRID:121636 ARHGAP21 BioGRID PMID: 34591612,25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121677 ARHGAP23 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114806 ARHGAP29 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115091 ARHGAP32 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:106887 ARHGAP5 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:106890 ARHGDIB BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116945 ARHGEF12 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:118085 ARHGEF16 BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:130905 ARMH1 BioGRID PMID: 35559673 +Affinity Capture-Western +BioGRID:107434 BioGRID:115415 ARPC2 BioGRID PMID: 11882288 +Proximity Label-MS +BioGRID:107434 BioGRID:131507 ARPIN BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:106914 ARVCF BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:119126 ASAP1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:106961 ATIC BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:106980 ATP2B1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:106983 ATP2B4 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116429 ATXN2L BioGRID PMID: 25468996 +Reconstituted Complex +BioGRID:107434 BioGRID:114646 AURKB BioGRID PMID: 34509474 +Proximity Label-MS +BioGRID:107434 BioGRID:114907 BAG3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115721 BAIAP2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121017 BAIAP2L1 BioGRID PMID: 25468996 +Co-fractionation +BioGRID:107434 BioGRID:114934 BCAR1 BioGRID PMID: 35831314 +Proximity Label-MS +BioGRID:107434 BioGRID:107071 BCL2L2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:107127 BMPR2 BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:107140 BRCA1 BioGRID PMID: 28319113 +Proximity Label-MS +BioGRID:107434 BioGRID:107147 BSG BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:107164 BUB1 BioGRID PMID: 35559673 +Proximity Label-MS +BioGRID:107434 BioGRID:115042 BZW1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:118793 BZW2 BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:131169 C16orf96 BioGRID PMID: 35559673 +Affinity Capture-MS +BioGRID:107434 BioGRID:107169 C1QBP BioGRID PMID: 16212417 +Proximity Label-MS +BioGRID:107434 BioGRID:122545 C1orf116 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:124327 C1orf198 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:122586 C1orf35 BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:937613 C2CD4D BioGRID PMID: 35559673 +Proximity Label-MS +BioGRID:107434 BioGRID:571814 C6orf132 BioGRID PMID: 25468996 +Affinity Capture-Western +BioGRID:107434 BioGRID:107223 CA9 BioGRID PMID: 14567991 +Proximity Label-MS +BioGRID:107434 BioGRID:107251 CALD1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121382 CAMK1D BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:125875 CANT1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:107272 CAPG BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:110252 CAPRIN1 BioGRID PMID: 35559673 +Proximity Label-MS +BioGRID:107434 BioGRID:107278 CAPS BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:107279 CAPZA1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:107282 CAPZB BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:120745 CARMIL1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121577 CASKIN2 BioGRID PMID: 25468996 +Co-localization +BioGRID:107434 BioGRID:107286 CASP3 BioGRID PMID: 25241761 +Proximity Label-MS +BioGRID:107434 BioGRID:107281 CAST BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:107315 CBL BioGRID PMID: 25468996 +Affinity Capture-Western; Co-localization; FRET; Two-hybrid +BioGRID:107434 BioGRID:122960 CBLL1 BioGRID PMID: 29356040,28069439,22850631,22715382,22252131,21685945,19711372,18057010,16336960,11836526 +Proximity Label-MS +BioGRID:107434 BioGRID:120212 CC2D1A BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:124658 CCDC120 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:125890 CCDC43 BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:124553 CCDC65 BioGRID PMID: 35559673 +Proximity Label-MS +BioGRID:107434 BioGRID:130463 CCDC85C BioGRID PMID: 25468996 +Biochemical Activity +BioGRID:107434 BioGRID:107332 CCNB1 BioGRID PMID: 34942119 +Proximity Label-MS +BioGRID:107434 BioGRID:114581 CCNB2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115298 CCS BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:119968 CCSER2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115933 CCT8 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:117140 CD2AP BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:110420 CD99 BioGRID PMID: 25468996 +Affinity Capture-Western +BioGRID:107434 BioGRID:107431 CDC27 BioGRID PMID: 22539978,20686030 +Affinity Capture-Western; Reconstituted Complex +BioGRID:107434 BioGRID:107433 CDC42 BioGRID PMID: 18057010 +Proximity Label-MS +BioGRID:107434 BioGRID:116308 CDC42EP1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:117115 CDC42EP4 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:123657 CDCA3 BioGRID PMID: 25468996 +Affinity Capture-Western; Reconstituted Complex +BioGRID:107434 BioGRID:120446 CDCA8 BioGRID PMID: 32934012 +Affinity Capture-Western; Co-purification; Reconstituted Complex +BioGRID:107434 BioGRID:107434 CDH1 BioGRID PMID: 10910767,10202138 +Affinity Capture-Western; Co-purification +BioGRID:107434 BioGRID:107436 CDH3 BioGRID PMID: 10910767 +Affinity Capture-MS +BioGRID:107434 BioGRID:107441 CDH8 BioGRID PMID: 33961781 +Affinity Capture-MS +BioGRID:107434 BioGRID:132983 CDHR4 BioGRID PMID: 33961781 +Affinity Capture-Western +BioGRID:107434 BioGRID:107454 CDK4 BioGRID PMID: 35525274 +Affinity Capture-Western +BioGRID:107434 BioGRID:114376 CDK5R1 BioGRID PMID: 16029324 +Affinity Capture-Western +BioGRID:107434 BioGRID:107456 CDK6 BioGRID PMID: 35525274 +Two-hybrid +BioGRID:107434 BioGRID:107458 CDK8 BioGRID PMID: 24412244 +Proximity Label-MS +BioGRID:107434 BioGRID:112668 CDKL5 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:117188 CEMIP2 BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:107506 CFTR BioGRID PMID: 26618866,17110338 +Proximity Label-MS +BioGRID:107434 BioGRID:121589 CGN BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:107533 CHD4 BioGRID PMID: 35559673 +Reconstituted Complex +BioGRID:107434 BioGRID:107536 CHEK1 BioGRID PMID: 34509474 +Proximity Label-MS +BioGRID:107434 BioGRID:117462 CHMP2B BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:126170 CHMP4B BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:119579 CHMP5 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121328 CIAPIN1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121687 CIP2A BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115137 CKAP5 BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:107600 CLCN7 BioGRID PMID: 34591612 +Affinity Capture-MS +BioGRID:107434 BioGRID:119158 CLEC4A BioGRID PMID: 33961781 +Proximity Label-MS +BioGRID:107434 BioGRID:107604 CLIC1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115038 CLINT1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:122889 CLMN BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:107665 CNN2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:107666 CNN3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116511 COBLL1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:107704 COL17A1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:117926 COPG2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121425 CORO1B BioGRID PMID: 25468996 +Affinity Capture-Western; Reconstituted Complex +BioGRID:107434 BioGRID:107777 CREBBP BioGRID PMID: 19114997,16319895 +Proximity Label-MS +BioGRID:107434 BioGRID:107788 CRK BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:107789 CRKL BioGRID PMID: 25468996 +Affinity Capture-Western +BioGRID:107434 BioGRID:107800 CRYAB BioGRID PMID: 22158051 +Proximity Label-MS +BioGRID:107434 BioGRID:106705 CRYBG1 BioGRID PMID: 25468996 +Affinity Capture-Western; Reconstituted Complex +BioGRID:107434 BioGRID:107821 CSE1L BioGRID PMID: 20734115,12061792 +Affinity Capture-MS; Proximity Label-MS +BioGRID:107434 BioGRID:107836 CSNK1A1 BioGRID PMID: 27684187,25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:107837 CSNK1D BioGRID PMID: 25468996 +Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Proximity Label-MS +BioGRID:107434 BioGRID:107876 CTNNA1 BioGRID PMID: 35831314,34591612,25468996,16212417,11960376,10381631,9233779,8227214,7542250 +Affinity Capture-MS; Proximity Label-MS +BioGRID:107434 BioGRID:107877 CTNNA2 BioGRID PMID: 34591612,25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:118885 CTNNA3 BioGRID PMID: 33961781,28514442 +Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-fractionation; Co-localization; FRET; Proximity Label-MS; Reconstituted Complex +BioGRID:107434 BioGRID:107880 CTNNB1 BioGRID PMID: 35831314,35271311,34591612,33961781,31286874,29789528,28966723,27684187,26707622,25468996,25466890,24798214,23180380,22850631,22752307,22715382,22375065,22158051,19223551,18593907,17909039,17220478,16574648,16212417,16125672,15023525,12830000,12640114,12169098,12061792,11960376,11712088,11348595,11254878,11245482,11113628,10772923,10381631,9819408,9535896,9405455,9233779,8227214,7954478,7876318,7542250 +Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-localization; FRET; Proximity Label-MS; Reconstituted Complex; Two-hybrid +BioGRID:107434 BioGRID:107881 CTNND1 BioGRID PMID: 34591612,33961781,29207493,26707622,25468996,25466890,23180380,22850631,22752307,22715382,21670201,20371349,19711372,19114997,12707304,12640114,12427869,10409703,9535896,7876318,7651399,7542250 +Proximity Label-MS +BioGRID:107434 BioGRID:107888 CTSB BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108332 CTTN BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:107905 CXADR BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116648 DAAM1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:127478 DAB2IP BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:107975 DAG1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:107995 DBN1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:118809 DBNL BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:117545 DCAF4 BioGRID PMID: 30945288 +Negative Genetic +BioGRID:107434 BioGRID:124027 DDI2 BioGRID PMID: 35559673 +Affinity Capture-Western +BioGRID:107434 BioGRID:107234 DDR1 BioGRID PMID: 20432435 +Affinity Capture-Western +BioGRID:107434 BioGRID:110975 DDR2 BioGRID PMID: 20432435 +Negative Genetic +BioGRID:107434 BioGRID:120592 DDX19A BioGRID PMID: 35559673 +Affinity Capture-MS; Proximity Label-MS +BioGRID:107434 BioGRID:113649 DDX39B BioGRID PMID: 27684187,25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108020 DDX3X BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108022 DDX6 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:120799 DENND4C BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:120001 DHX29 BioGRID PMID: 25468996 +Co-fractionation +BioGRID:107434 BioGRID:108073 DIAPH1 BioGRID PMID: 35831314 +Proximity Label-MS +BioGRID:107434 BioGRID:123559 DIAPH3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108083 DLG1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114662 DLG5 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:109569 DNAJB1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116930 DOCK9 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108159 DSC3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108163 DSG2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:107135 DST BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:116246 DUS4L BioGRID PMID: 33961781 +Proximity Label-MS +BioGRID:107434 BioGRID:108190 DVL3 BioGRID PMID: 25468996 +Affinity Capture-Western +BioGRID:107434 BioGRID:108201 E2F1 BioGRID PMID: 20948288 +Proximity Label-MS +BioGRID:107434 BioGRID:116166 EBNA1BP2 BioGRID PMID: 25468996 +Affinity Capture-Western +BioGRID:107434 BioGRID:108223 ECT2 BioGRID PMID: 21886810 +Proximity Label-MS +BioGRID:107434 BioGRID:108237 EEF1A1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108256 EEF1D BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108257 EEF1G BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108258 EEF2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:122597 EFHD2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116779 EFR3A BioGRID PMID: 25468996 +Affinity Capture-MS; Affinity Capture-Western; Co-localization; PCA; Proximity Label-MS; Two-hybrid +BioGRID:107434 BioGRID:108276 EGFR BioGRID PMID: 25468996,25402006,25241761,24658140,24189400,10969083 +Proximity Label-MS +BioGRID:107434 BioGRID:116893 EHBP1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:129015 EHBP1L1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116138 EHD1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:119054 EHD4 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:123822 EIF2A BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108287 EIF2S3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:109857 EIF3E BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108291 EIF4B BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108296 EIF4G1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108297 EIF4G2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:113297 EIF4H BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108298 EIF5 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108299 EIF5A BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:125356 ELFN2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:123927 ELMOD3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:117764 ELP4 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108325 EMD BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108338 ENO1 BioGRID PMID: 25468996 +Affinity Capture-Western +BioGRID:107434 BioGRID:108347 EP300 BioGRID PMID: 16319895 +Proximity Label-MS +BioGRID:107434 BioGRID:108349 EPB41 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108350 EPB41L1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116753 EPB41L3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:120044 EPB41L4B BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108288 EPHA2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116569 EPN2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:120369 EPN3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108374 EPS15 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121840 EPS15L1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:120218 EPS8L1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:122297 EPS8L2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108376 ERBB2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108377 ERBB3 BioGRID PMID: 25468996 +Affinity Capture-MS; Proximity Label-MS +BioGRID:107434 BioGRID:120997 ERBIN BioGRID PMID: 34591612,25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116714 ERC1 BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:108404 ESR2 BioGRID PMID: 29509190 +Proximity Label-MS +BioGRID:107434 BioGRID:116927 ESYT1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121556 ESYT2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108426 EVPL BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116464 EXOC3 BioGRID PMID: 25468996 +Affinity Capture-Western; Proximity Label-MS +BioGRID:107434 BioGRID:113271 EZR BioGRID PMID: 25468996,10462524 +Proximity Label-MS +BioGRID:107434 BioGRID:119153 F11R BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:123674 FAM110A BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:567837 FAM110C BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:127911 FAM171B BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:128805 FAM83B BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:130292 FAM83H BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:127622 FAM91A1 BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:108473 FANCC BioGRID PMID: 35559673 +Negative Genetic +BioGRID:107434 BioGRID:108474 FANCD2 BioGRID PMID: 35559673 +Negative Genetic +BioGRID:107434 BioGRID:108483 FANCF BioGRID PMID: 35559673 +Reconstituted Complex +BioGRID:107434 BioGRID:115189 FARP2 BioGRID PMID: 35525274 +Proximity Label-MS +BioGRID:107434 BioGRID:108488 FASN BioGRID PMID: 25468996 +Reconstituted Complex +BioGRID:107434 BioGRID:108532 FER BioGRID PMID: 12640114 +Proximity Label-MS +BioGRID:107434 BioGRID:120752 FERMT1 BioGRID PMID: 25468996 +Co-localization; Reconstituted Complex +BioGRID:107434 BioGRID:108551 FGFR1 BioGRID PMID: 27371729,25241761 +Proximity Label-MS +BioGRID:107434 BioGRID:108605 FLNA BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108606 FLNB BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115506 FLOT1 BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:117269 FLRT1 BioGRID PMID: 33961781 +Proximity Label-MS +BioGRID:107434 BioGRID:131167 FMN1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:125355 FMNL2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:120222 FNBP1L BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116031 FRS2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112508 FSCN1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108773 FTH1 BioGRID PMID: 25468996 +Affinity Capture-Western; Reconstituted Complex +BioGRID:107434 BioGRID:108810 FYN BioGRID PMID: 12640114 +Proximity Label-MS +BioGRID:107434 BioGRID:108824 GAB1 BioGRID PMID: 25468996 +Two-hybrid +BioGRID:107434 BioGRID:122816 GALNT12 BioGRID PMID: 24412244 +Proximity Label-MS +BioGRID:107434 BioGRID:117568 GAPVD1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116181 GCN1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:126937 GCOM1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116775 GGA3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:117520 GIGYF2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115978 GIPC1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:119237 GLOD4 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:109022 GM2A BioGRID PMID: 25468996 +Affinity Capture-Western +BioGRID:107434 BioGRID:119246 GMNN BioGRID PMID: 23695679 +Reconstituted Complex +BioGRID:107434 BioGRID:109030 GNA12 BioGRID PMID: 11136230 +Reconstituted Complex +BioGRID:107434 BioGRID:115914 GNA13 BioGRID PMID: 11136230 +Proximity Label-MS +BioGRID:107434 BioGRID:109063 GOLGA2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:109064 GOLGA3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115275 GOLGA5 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:136421 GOLGA8B BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:109066 GOLGB1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:117479 GORASP2 BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:109067 GOT1 BioGRID PMID: 33961781 +Affinity Capture-MS +BioGRID:107434 BioGRID:109079 GPC1 BioGRID PMID: 27576135 +Negative Genetic +BioGRID:107434 BioGRID:123786 GPR61 BioGRID PMID: 35559673 +Proximity Label-MS +BioGRID:107434 BioGRID:114514 GPRC5A BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:125349 GPRIN1 BioGRID PMID: 25468996 +Co-localization +BioGRID:107434 BioGRID:109187 GSK3B BioGRID PMID: 25241761 +Proximity Label-MS +BioGRID:107434 BioGRID:109190 GSPT1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114461 H1-10 BioGRID PMID: 25468996 +Co-fractionation +BioGRID:107434 BioGRID:109263 H1-4 BioGRID PMID: 35831314 +Co-localization; Proximity Label-MS +BioGRID:107434 BioGRID:113946 H3C1 BioGRID PMID: 29466696,25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:109280 HADHA BioGRID PMID: 34591612 +Affinity Capture-MS +BioGRID:107434 BioGRID:109282 HADHB BioGRID PMID: 34591612 +Proximity Label-MS +BioGRID:107434 BioGRID:109304 HCFC1 BioGRID PMID: 25468996 +Affinity Capture-Western; Co-purification +BioGRID:107434 BioGRID:109315 HDAC1 BioGRID PMID: 15388328 +Affinity Capture-Western; Co-localization; Co-purification +BioGRID:107434 BioGRID:109316 HDAC2 BioGRID PMID: 25241761,15388328 +Proximity Label-MS +BioGRID:107434 BioGRID:109319 HDLBP BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:117359 HECTD1 BioGRID PMID: 29511261 +Two-hybrid +BioGRID:107434 BioGRID:120641 HEMGN BioGRID PMID: 24412244 +Proximity Label-MS +BioGRID:107434 BioGRID:109352 HLA-C BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:128670 HNRNPA3 BioGRID PMID: 35559673 +Proximity Label-MS +BioGRID:107434 BioGRID:109431 HNRNPK BioGRID PMID: 25468996 +Two-hybrid +BioGRID:107434 BioGRID:109501 HRAS BioGRID PMID: 24412244 +Two-hybrid +BioGRID:107434 BioGRID:109526 HSD17B3 BioGRID PMID: 24412244 +Affinity Capture-MS +BioGRID:107434 BioGRID:109552 HSP90AA1 BioGRID PMID: 16212417 +Proximity Label-MS +BioGRID:107434 BioGRID:109558 HSP90AB1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:109535 HSPA1A BioGRID PMID: 25468996 +Affinity Capture-MS; Proximity Label-MS +BioGRID:107434 BioGRID:109541 HSPA5 BioGRID PMID: 25468996,16212417 +Affinity Capture-MS; Proximity Label-MS +BioGRID:107434 BioGRID:109544 HSPA8 BioGRID PMID: 27684187,25468996,16212417 +Affinity Capture-MS +BioGRID:107434 BioGRID:109545 HSPA9 BioGRID PMID: 16212417 +Negative Genetic +BioGRID:107434 BioGRID:118020 HSPB7 BioGRID PMID: 35559673 +Affinity Capture-MS +BioGRID:107434 BioGRID:109561 HSPD1 BioGRID PMID: 16212417 +Proximity Label-MS +BioGRID:107434 BioGRID:124188 HYCC1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:130030 HYCC2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:109643 IDH1 BioGRID PMID: 25468996 +Affinity Capture-Western +BioGRID:107434 BioGRID:109644 IDH2 BioGRID PMID: 34271087 +Proximity Label-MS +BioGRID:107434 BioGRID:109698 IGBP1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:109703 IGF2R BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:109714 IGHA1 BioGRID PMID: 16212417 +Co-fractionation +BioGRID:107434 BioGRID:109819 IL18 BioGRID PMID: 35831314 +Proximity Label-MS +BioGRID:107434 BioGRID:109786 IL6ST BioGRID PMID: 25468996 +Co-fractionation +BioGRID:107434 BioGRID:109821 ILF2 BioGRID PMID: 35831314 +Affinity Capture-MS +BioGRID:107434 BioGRID:109824 ILK BioGRID PMID: 25852190 +Proximity Label-MS +BioGRID:107434 BioGRID:120883 INAVA BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:109848 INPPL1 BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:109842 INS BioGRID PMID: 32457219 +Affinity Capture-Western; Proximity Label-MS; Reconstituted Complex +BioGRID:107434 BioGRID:114353 IQGAP1 BioGRID PMID: 25468996,10608854 +Proximity Label-MS +BioGRID:107434 BioGRID:109863 IRAK1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115141 IST1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:119562 ISYNA1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:109864 ITGA6 BioGRID PMID: 25468996 +Co-purification +BioGRID:107434 BioGRID:109888 ITGAE BioGRID PMID: 12434297 +Proximity Label-MS +BioGRID:107434 BioGRID:109894 ITGB1 BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:109901 ITGB7 BioGRID PMID: 35559673 +Proximity Label-MS +BioGRID:107434 BioGRID:112622 ITPRID2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:109917 IVL BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121655 JCAD BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:119338 JPT1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:124774 JPT2 BioGRID PMID: 25468996 +Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Proximity Label-MS; Reconstituted Complex +BioGRID:107434 BioGRID:109931 JUP BioGRID PMID: 35831314,34591612,27684187,25468996,22375065,14517306,9535896,8207061,8074697,7542250,1639850 +Proximity Label-MS +BioGRID:107434 BioGRID:117449 KANK2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:109984 KCNN4 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:126010 KDF1 BioGRID PMID: 25468996 +Affinity Capture-Western; Proximity Label-MS; Reconstituted Complex +BioGRID:107434 BioGRID:115156 KEAP1 BioGRID PMID: 25468996,22302998 +Proximity Label-MS +BioGRID:107434 BioGRID:121111 KIAA1217 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121685 KIAA1522 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:124506 KIAA1671 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121565 KIDINS220 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:110000 KIF5B BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:122313 KLC2 BioGRID PMID: 25468996 +Affinity Capture-Western +BioGRID:107434 BioGRID:114726 KLF4 BioGRID PMID: 21177849 +Affinity Capture-MS +BioGRID:107434 BioGRID:110043 KRAS BioGRID PMID: 27684187 +Affinity Capture-MS +BioGRID:107434 BioGRID:110046 KRT1 BioGRID PMID: 16212417 +Affinity Capture-MS; Proximity Label-MS +BioGRID:107434 BioGRID:110073 KRT18 BioGRID PMID: 25468996,16212417 +Affinity Capture-MS +BioGRID:107434 BioGRID:110054 KRT8 BioGRID PMID: 16212417 +Affinity Capture-MS +BioGRID:107434 BioGRID:110055 KRT9 BioGRID PMID: 16212417 +Proximity Label-MS +BioGRID:107434 BioGRID:110092 KTN1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:110095 LAD1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116947 LARP1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:110120 LASP1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:110122 LBR BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:110131 LDHA BioGRID PMID: 25468996 +Affinity Capture-Western +BioGRID:107434 BioGRID:110150 LGALS3BP BioGRID PMID: 29207493 +Proximity Label-MS +BioGRID:107434 BioGRID:119559 LIMA1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116645 LIMCH1 BioGRID PMID: 25468996 +Co-fractionation +BioGRID:107434 BioGRID:110176 LIPA BioGRID PMID: 35831314 +Proximity Label-MS +BioGRID:107434 BioGRID:110183 LLGL1 BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:110186 LMNA BioGRID PMID: 16212417 +Proximity Label-MS +BioGRID:107434 BioGRID:110193 LMO7 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:110208 LPP BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:127609 LRATD2 BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:115432 LRPPRC BioGRID PMID: 34591612 +Proximity Label-MS +BioGRID:107434 BioGRID:129089 LRRC57 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:120649 LRRC59 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121610 LRRC7 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114642 LRRFIP1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:119629 LSR BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:113574 LUZP1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116444 LYPLA2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:124083 LZTS2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:4383846 M BioGRID PMID: 35337019 +Proximity Label-MS +BioGRID:107434 BioGRID:131381 MACC1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:117048 MACF1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114927 MACROH2A1 BioGRID PMID: 25468996 +Affinity Capture-Western; Reconstituted Complex +BioGRID:107434 BioGRID:115722 MAD2L2 BioGRID PMID: 32811646 +Affinity Capture-Western; Proximity Label-MS +BioGRID:107434 BioGRID:114655 MAGI1 BioGRID PMID: 25468996,10772923 +Proximity Label-MS +BioGRID:107434 BioGRID:129277 MAGI3 BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:110290 MAGOH BioGRID PMID: 35559673 +Two-hybrid +BioGRID:107434 BioGRID:111590 MAP2K1 BioGRID PMID: 24412244 +Proximity Label-MS +BioGRID:107434 BioGRID:110306 MAP4 BioGRID PMID: 25468996 +Two-hybrid +BioGRID:107434 BioGRID:111581 MAPK3 BioGRID PMID: 24412244 +Proximity Label-MS +BioGRID:107434 BioGRID:116581 MAPRE1 BioGRID PMID: 25468996 +Affinity Capture-Western +BioGRID:107434 BioGRID:128666 MARCHF8 BioGRID PMID: 33540066 +Proximity Label-MS +BioGRID:107434 BioGRID:110257 MARCKS BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:108326 MARK2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:110310 MARK3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:127502 MARVELD2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121570 MAVS BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:110319 MAX BioGRID PMID: 35559673 +Proximity Label-MS +BioGRID:107434 BioGRID:127413 MB21D2 BioGRID PMID: 25468996 +Affinity Capture-Western; Biochemical Activity; Reconstituted Complex +BioGRID:107434 BioGRID:110358 MDM2 BioGRID PMID: 32805084,31337857,25086032,16980628 +Affinity Capture-Western +BioGRID:107434 BioGRID:110391 MET BioGRID PMID: 11254878 +Proximity Label-MS +BioGRID:107434 BioGRID:124504 MICALL1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:119075 MINK1 BioGRID PMID: 25468996 +Biochemical Activity +BioGRID:107434 BioGRID:110434 MKI67 BioGRID PMID: 34942119 +Proximity Label-MS +BioGRID:107434 BioGRID:126785 MPP7 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116776 MPRIP BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114486 MPZL1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:110501 MRE11 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121563 MRTFB BioGRID PMID: 25468996 +Two-hybrid +BioGRID:107434 BioGRID:124810 MSANTD3 BioGRID PMID: 24412244 +Proximity Label-MS +BioGRID:107434 BioGRID:110712 MYH9 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:110567 MYO1B BioGRID PMID: 25468996 +Proximity Label-MS; Reconstituted Complex +BioGRID:107434 BioGRID:110730 MYO6 BioGRID PMID: 25468996,23007415 +Affinity Capture-Western +BioGRID:107434 BioGRID:110731 MYO7A BioGRID PMID: 11080149 +Biochemical Activity +BioGRID:107434 BioGRID:201430 Mki67 BioGRID PMID: 34942119 +Proximity Label-MS +BioGRID:107434 BioGRID:115036 N4BP1 BioGRID PMID: 25468996 +Two-hybrid +BioGRID:107434 BioGRID:119921 NANS BioGRID PMID: 24412244 +Proximity Label-MS +BioGRID:107434 BioGRID:124606 NAV2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:110770 NCK1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114020 NCK2 BioGRID PMID: 25468996 +Affinity Capture-Western; Co-fractionation; Proximity Label-MS +BioGRID:107434 BioGRID:115669 NDRG1 BioGRID PMID: 25468996,17786215,17220478 +Proximity Label-MS +BioGRID:107434 BioGRID:121520 NDRG2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115784 NEBL BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111776 NECTIN1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111777 NECTIN2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:123544 NECTIN4 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:110844 NF2 BioGRID PMID: 25468996 +Affinity Capture-Western; Reconstituted Complex +BioGRID:107434 BioGRID:110852 NFE2L2 BioGRID PMID: 22302998 +Proximity Label-MS +BioGRID:107434 BioGRID:110861 NFKBIE BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:117466 NGDN BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114769 NHERF1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114754 NHERF2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:110875 NHS BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121460 NHSL1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:122328 NIBAN2 BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:114080 NIPSNAP1 BioGRID PMID: 16212417 +Affinity Capture-MS +BioGRID:107434 BioGRID:108901 NIPSNAP2 BioGRID PMID: 16212417 +Co-fractionation +BioGRID:107434 BioGRID:124517 NKD2 BioGRID PMID: 20177058 +Proximity Label-MS +BioGRID:107434 BioGRID:120787 NLRP2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115783 NOP56 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:110913 NOTCH1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:110915 NOTCH2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:110916 NOTCH3 BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:114012 NR0B2 BioGRID PMID: 35559673 +Affinity Capture-MS +BioGRID:107434 BioGRID:108375 NR2F6 BioGRID PMID: 33961781 +Proximity Label-MS +BioGRID:107434 BioGRID:121014 NSFL1C BioGRID PMID: 25468996 +Co-fractionation +BioGRID:107434 BioGRID:120236 NSUN2 BioGRID PMID: 35831314 +Proximity Label-MS +BioGRID:107434 BioGRID:115950 NUDC BioGRID PMID: 25468996 +Co-fractionation; Proximity Label-MS +BioGRID:107434 BioGRID:116335 NUDT5 BioGRID PMID: 35831314,25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114202 NUMB BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114677 NUMBL BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:113717 NUP214 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111004 OCLN BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:118917 OLA1 BioGRID PMID: 25468996 +Affinity Capture-MS; Two-hybrid +BioGRID:107434 BioGRID:4383871 ORF7b BioGRID PMID: 36217030 +Proximity Label-MS +BioGRID:107434 BioGRID:116413 PACSIN2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:120931 PAG1 BioGRID PMID: 25468996 +Affinity Capture-Western +BioGRID:107434 BioGRID:111090 PAH BioGRID PMID: 33260674 +Proximity Label-MS +BioGRID:107434 BioGRID:115852 PAICS BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111098 PAK2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115586 PAK4 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121251 PAK6 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116386 PALM2AKAP2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:131220 PALM3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121134 PARD3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116446 PARK7 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:120860 PARVA BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115502 PATJ BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111126 PCBP1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111127 PCBP2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111130 PCDH1 BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:111131 PCDHGC3 BioGRID PMID: 33961781,28514442 +Proximity Label-MS +BioGRID:107434 BioGRID:111141 PCMT1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116461 PDAP1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114572 PDLIM1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115857 PDLIM5 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114682 PDLIM7 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116681 PDXDC1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:122926 PEAK1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111235 PFKP BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111237 PFN1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115693 PGRMC2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115097 PHACTR2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:122429 PHACTR4 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:124661 PHLDB2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111315 PI4KA BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:113902 PICALM BioGRID PMID: 25468996 +Affinity Capture-Western; FRET +BioGRID:107434 BioGRID:116969 PIP5K1C BioGRID PMID: 22850631,22375065 +Affinity Capture-Western +BioGRID:107434 BioGRID:111327 PKD1 BioGRID PMID: 21126580 +Proximity Label-MS +BioGRID:107434 BioGRID:111332 PKM BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111572 PKN2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111335 PKP2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116357 PKP3 BioGRID PMID: 25468996 +Affinity Capture-MS; Proximity Label-MS; Two-hybrid +BioGRID:107434 BioGRID:114074 PKP4 BioGRID PMID: 34591612,25468996,12615965 +Proximity Label-MS +BioGRID:107434 BioGRID:111347 PLCB3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111355 PLEC BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121880 PLEKHA1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121881 PLEKHA2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:119982 PLEKHA5 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116541 PLEKHA6 BioGRID PMID: 25468996 +Affinity Capture-MS; Proximity Label-MS +BioGRID:107434 BioGRID:126828 PLEKHA7 BioGRID PMID: 34591612,25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:123215 PLEKHO2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115520 PLIN3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111373 PLSCR1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121341 PLSCR3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:123048 POF1B BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:111430 POLR2E BioGRID PMID: 16212417 +Proximity Label-MS +BioGRID:107434 BioGRID:114068 PPFIBP1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111488 PPL BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:119524 PPME1 BioGRID PMID: 25468996 +Affinity Capture-Western; Proximity Label-MS +BioGRID:107434 BioGRID:111493 PPP1CA BioGRID PMID: 25468996,17274640 +Proximity Label-MS +BioGRID:107434 BioGRID:116948 PPP1R13B BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116059 PPP1R13L BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:128092 PPP1R18 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:129838 PPP1R37 BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:120344 PPP2R3C BioGRID PMID: 35559673 +Proximity Label-MS +BioGRID:107434 BioGRID:111089 PRDX1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114956 PRDX6 BioGRID PMID: 25468996 +Co-fractionation +BioGRID:107434 BioGRID:111577 PRKDC BioGRID PMID: 35831314 +Proximity Label-MS +BioGRID:107434 BioGRID:127318 PROM2 BioGRID PMID: 25468996 +Affinity Capture-MS; Affinity Capture-Western +BioGRID:107434 BioGRID:111642 PSEN1 BioGRID PMID: 34591612,19114997,16126725,10635315 +Proximity Label-MS +BioGRID:107434 BioGRID:111667 PSMB6 BioGRID PMID: 25468996 +Affinity Capture-Western; Co-fractionation +BioGRID:107434 BioGRID:111719 PTK2 BioGRID PMID: 35831314,35525274 +Proximity Label-MS +BioGRID:107434 BioGRID:111736 PTPN1 BioGRID PMID: 25468996 +Affinity Capture-Western +BioGRID:107434 BioGRID:111753 PTPRD BioGRID PMID: 21126580 +Affinity Capture-Western +BioGRID:107434 BioGRID:111757 PTPRG BioGRID PMID: 21126580 +Proximity Label-MS +BioGRID:107434 BioGRID:111759 PTPRJ BioGRID PMID: 25468996 +Affinity Capture-Western +BioGRID:107434 BioGRID:111761 PTPRM BioGRID PMID: 9531566 +Affinity Capture-Western +BioGRID:107434 BioGRID:111766 PTPRS BioGRID PMID: 21126580 +Biochemical Activity +BioGRID:107434 BioGRID:114663 PTTG1 BioGRID PMID: 34942119 +Proximity Label-MS +BioGRID:107434 BioGRID:116502 PUF60 BioGRID PMID: 25468996 +Co-fractionation; Proximity Label-MS +BioGRID:107434 BioGRID:111787 PXN BioGRID PMID: 35831314,25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116096 RAB10 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114661 RAB11B BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111799 RAB1A BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:121377 RAB25 BioGRID PMID: 35559673 +Affinity Capture-Western +BioGRID:107434 BioGRID:119719 RAB8B BioGRID PMID: 12639940 +Proximity Label-MS +BioGRID:107434 BioGRID:115671 RACK1 BioGRID PMID: 25468996 +Affinity Capture-MS; Affinity Capture-Western +BioGRID:107434 BioGRID:111821 RAD17 BioGRID PMID: 20424596 +Proximity Label-MS +BioGRID:107434 BioGRID:117526 RAI14 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111837 RAN BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111838 RANBP1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111840 RANGAP1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:122380 RAPH1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111852 RARS1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115160 RB1CC1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:111894 RDX BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:612841 RELL1 BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:106880 RHOA BioGRID PMID: 31980649 +Negative Genetic +BioGRID:107434 BioGRID:125466 RMI2 BioGRID PMID: 35559673 +Affinity Capture-MS +BioGRID:107434 BioGRID:111972 RNF2 BioGRID PMID: 24457600 +Affinity Capture-Western; Biochemical Activity +BioGRID:107434 BioGRID:120241 RNF43 BioGRID PMID: 31286874 +Co-fractionation +BioGRID:107434 BioGRID:112020 ROCK1 BioGRID PMID: 35831314 +Co-fractionation +BioGRID:107434 BioGRID:114860 ROCK2 BioGRID PMID: 35831314 +Proximity Label-MS +BioGRID:107434 BioGRID:114507 RPL14 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112058 RPL15 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112067 RPL23A BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112071 RPL24 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112078 RPL29 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112083 RPL34 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112092 RPL36A BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112085 RPL36AL BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112086 RPL37 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112048 RPL6 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112050 RPL7A BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112101 RPS2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112145 RPS26 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:117587 RSL1D1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121400 RTN4 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114166 RUVBL1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112190 S100A11 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112194 S100P BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:134996 SAPCD1 BioGRID PMID: 33961781 +Proximity Label-MS +BioGRID:107434 BioGRID:131933 SBSN BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:107387 SCARB1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114324 SCEL BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:117060 SCRIB BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121512 SCYL1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:120810 SCYL2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112287 SDCBP BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115696 SEC24B BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:110812 SEPTIN2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:107425 SEPTIN7 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116015 SEPTIN9 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:117571 SERBP1 BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:112316 SET BioGRID PMID: 16212417 +Proximity Label-MS +BioGRID:107434 BioGRID:109072 SFN BioGRID PMID: 25468996 +Two-hybrid +BioGRID:107434 BioGRID:112321 SFRP2 BioGRID PMID: 24412244 +Affinity Capture-MS +BioGRID:107434 BioGRID:112340 SGCA BioGRID PMID: 33961781 +Affinity Capture-MS +BioGRID:107434 BioGRID:114398 SGPL1 BioGRID PMID: 34591612 +Proximity Label-MS +BioGRID:107434 BioGRID:127448 SH3D19 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112352 SH3GL1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:119289 SH3GLB1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121234 SH3GLB2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:119029 SH3KBP1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:130149 SH3PXD2B BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121673 SH3RF1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116598 SHANK2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112358 SHB BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121665 SHROOM3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121723 SHTN1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116722 SIPA1L3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:126752 SIRPA BioGRID PMID: 25468996 +Affinity Capture-Western +BioGRID:107434 BioGRID:119603 SIRT6 BioGRID PMID: 34244565 +Affinity Capture-Western; Biochemical Activity +BioGRID:107434 BioGRID:112393 SKP2 BioGRID PMID: 26474281,20717963 +Proximity Label-MS +BioGRID:107434 BioGRID:112447 SLC12A2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114571 SLC16A3 BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:112460 SLC18A3 BioGRID PMID: 35559673 +Proximity Label-MS +BioGRID:107434 BioGRID:112401 SLC1A5 BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:116192 SLC27A4 BioGRID PMID: 34591612 +Proximity Label-MS +BioGRID:107434 BioGRID:126837 SLC2A14 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:113560 SLC30A1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:123509 SLC38A1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112411 SLC3A2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114876 SLC4A7 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112438 SLC9A1 BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:123624 SLIRP BioGRID PMID: 33961781 +Proximity Label-MS +BioGRID:107434 BioGRID:115096 SLK BioGRID PMID: 25468996 +Co-fractionation +BioGRID:107434 BioGRID:110263 SMAD3 BioGRID PMID: 35831314 +Affinity Capture-Western +BioGRID:107434 BioGRID:110267 SMAD7 BioGRID PMID: 18593713 +Proximity Label-MS +BioGRID:107434 BioGRID:114303 SNAP23 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112500 SNAP25 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114748 SNAP29 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:117974 SND1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112525 SNX1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112526 SNX2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:118022 SNX5 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:119535 SNX9 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115831 SORBS1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112556 SPAG1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:124953 SPECC1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:127800 SPRED1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112585 SPRR3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112587 SPTAN1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112589 SPTBN1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112590 SPTBN2 BioGRID PMID: 25468996 +Affinity Capture-Western; Proximity Label-MS +BioGRID:107434 BioGRID:112592 SRC BioGRID PMID: 31286874,25468996,21685945,18057010,10744074 +Proximity Label-MS +BioGRID:107434 BioGRID:123275 SRCIN1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116956 SRGAP2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:120299 SSH3 BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:119039 ST6GALNAC6 BioGRID PMID: 33961781 +Proximity Label-MS +BioGRID:107434 BioGRID:112649 STAT1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112650 STAT2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:120533 STEAP3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112662 STIM1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114011 STK24 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116457 STK38 BioGRID PMID: 25468996 +Two-hybrid +BioGRID:107434 BioGRID:120346 STX17 BioGRID PMID: 24412244 +Proximity Label-MS +BioGRID:107434 BioGRID:112679 STX4 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112680 STX5 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:118860 STXBP6 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112707 SVIL BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116707 SWAP70 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:125103 SYAP1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114388 SYNJ1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114391 SYNJ2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114525 SYT7 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:113995 TAGLN2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:124545 TANC1 BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:119061 TAX1BP3 BioGRID PMID: 33961781 +Proximity Label-MS +BioGRID:107434 BioGRID:123787 TBC1D10A BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:117476 TBC1D10B BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:120772 TBC1D22B BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:120836 TENM3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:117572 TES BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:112898 TGFB1 BioGRID PMID: 27684187 +Affinity Capture-MS +BioGRID:107434 BioGRID:112910 TGM2 BioGRID PMID: 16212417 +Proximity Label-MS +BioGRID:107434 BioGRID:112937 TJP1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114809 TJP2 BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:112938 TK1 BioGRID PMID: 34591612 +Co-fractionation; Proximity Label-MS +BioGRID:107434 BioGRID:112949 TLN1 BioGRID PMID: 35831314,25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:127028 TMEM199 BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:122780 TMEM204 BioGRID PMID: 35559673 +Proximity Label-MS +BioGRID:107434 BioGRID:120404 TMEM51 BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:124010 TMEM79 BioGRID PMID: 35559673 +Proximity Label-MS +BioGRID:107434 BioGRID:117453 TMEM87A BioGRID PMID: 25468996 +Two-hybrid +BioGRID:107434 BioGRID:112966 TMOD1 BioGRID PMID: 24412244 +Proximity Label-MS +BioGRID:107434 BioGRID:118899 TMOD3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:112967 TMPO BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:127753 TMTC2 BioGRID PMID: 34591612 +Negative Genetic +BioGRID:107434 BioGRID:119478 TNFRSF12A BioGRID PMID: 35559673 +Proximity Label-MS +BioGRID:107434 BioGRID:124540 TNKS1BP1 BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:113006 TOP2A BioGRID PMID: 35271311 +Affinity Capture-MS +BioGRID:107434 BioGRID:120213 TOR4A BioGRID PMID: 34591612 +Proximity Label-MS +BioGRID:107434 BioGRID:113012 TP53BP2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:113016 TPD52 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:113018 TPD52L2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:113500 TRIM25 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:117177 TRIM29 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114732 TRIP11 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:113056 TRIP6 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121455 TTC7A BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:113123 TTK BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:113124 TTN BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:128444 TUBB BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115656 TUBB4B BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:116462 TUSC2 BioGRID PMID: 35559673 +Proximity Label-MS +BioGRID:107434 BioGRID:111723 TWF1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:116472 TWF2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115487 TXNDC9 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:120392 UACA BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:120938 UBAP2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:113164 UBC BioGRID PMID: 25468996 +Co-crystal Structure +BioGRID:107434 BioGRID:116249 UBE2C BioGRID PMID: 34942119 +Negative Genetic +BioGRID:107434 BioGRID:118858 UBE2T BioGRID PMID: 35559673 +Proximity Label-MS +BioGRID:107434 BioGRID:121034 UBFD1 BioGRID PMID: 25468996 +Affinity Capture-RNA; Affinity Capture-Western; Protein-RNA +BioGRID:107434 BioGRID:535038 UCA1 BioGRID PMID: 32805084 +Biochemical Activity +BioGRID:107434 BioGRID:113194 UCHL3 BioGRID PMID: 24798214 +Co-localization +BioGRID:107434 BioGRID:118893 UHRF1 BioGRID PMID: 29466696 +Negative Genetic +BioGRID:107434 BioGRID:119697 UIMC1 BioGRID PMID: 35559673 +Biochemical Activity +BioGRID:107434 BioGRID:1678070 UL97 BioGRID PMID: 20686030 +Co-fractionation; Proximity Label-MS +BioGRID:107434 BioGRID:120986 UNC45A BioGRID PMID: 35831314,25468996 +Co-fractionation +BioGRID:107434 BioGRID:111908 UPF1 BioGRID PMID: 35831314 +Proximity Label-MS +BioGRID:107434 BioGRID:114173 USO1 BioGRID PMID: 25468996 +Negative Genetic +BioGRID:107434 BioGRID:114551 USP14 BioGRID PMID: 35559673 +Proximity Label-MS +BioGRID:107434 BioGRID:115283 USP15 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:125884 USP43 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115063 USP6NL BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114555 USP8 BioGRID PMID: 25468996 +Co-fractionation +BioGRID:107434 BioGRID:113867 USP9X BioGRID PMID: 14742711 +Proximity Label-MS +BioGRID:107434 BioGRID:113245 UTRN BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114747 VAMP3 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114651 VAPA BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:114650 VAPB BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:125406 VASN BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:113251 VASP BioGRID PMID: 25468996 +Affinity Capture-Western; Co-fractionation; Proximity Label-MS +BioGRID:107434 BioGRID:113257 VCL BioGRID PMID: 35831314,25468996,9535896,9405455 +Proximity Label-MS +BioGRID:107434 BioGRID:123125 VCPIP1 BioGRID PMID: 25468996 +Affinity Capture-Western +BioGRID:107434 BioGRID:120736 VEZT BioGRID PMID: 11080149 +Negative Genetic +BioGRID:107434 BioGRID:126479 VPS37A BioGRID PMID: 35559673 +Proximity Label-MS +BioGRID:107434 BioGRID:127065 VSIG10L BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115465 WASF2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:127043 WIPF2 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:119707 WWOX BioGRID PMID: 25468996 +Affinity Capture-MS +BioGRID:107434 BioGRID:113353 XRCC5 BioGRID PMID: 16212417 +Proximity Label-MS +BioGRID:107434 BioGRID:119970 XRN1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115684 YAP1 BioGRID PMID: 25468996 +Reconstituted Complex +BioGRID:107434 BioGRID:113357 YES1 BioGRID PMID: 12640114 +Proximity Label-MS +BioGRID:107434 BioGRID:115895 YKT6 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:113361 YWHAB BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:113363 YWHAE BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:113366 YWHAZ BioGRID PMID: 25468996 +Co-fractionation +BioGRID:107434 BioGRID:119290 ZC2HC1A BioGRID PMID: 35831314 +Proximity Label-MS +BioGRID:107434 BioGRID:120956 ZC3H15 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:121203 ZC3HAV1 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:117422 ZDHHC5 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:115111 ZFYVE16 BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:125855 ZG16B BioGRID PMID: 25468996 +Proximity Label-MS +BioGRID:107434 BioGRID:113525 ZNF185 BioGRID PMID: 25468996 +Two-hybrid +BioGRID:107434 BioGRID:116536 ZNF510 BioGRID PMID: 24412244 +Proximity Label-MS +BioGRID:107434 BioGRID:113569 ZYX BioGRID PMID: 25468996 + +GENERAL GENE INFO +------------------------------------------------------------------------------------------------- + +Marker + D11S2921 (e-PCR) Links:UniSTS:152074 + PMC84611P1 (e-PCR) Links:UniSTS:273449 + GDB:361044 (e-PCR) Links:UniSTS:156724 + GDB:361074 (e-PCR) Links:UniSTS:156725 + GDB:361084 (e-PCR) Links:UniSTS:156726 + GDB:361089 (e-PCR) Links:UniSTS:156727 + GDB:361093 (e-PCR) Links:UniSTS:156728 + GDB:361098 (e-PCR) Links:UniSTS:156729 + GDB:361103 (e-PCR) Links:UniSTS:156730 + GDB:361109 (e-PCR) Links:UniSTS:156731 + GDB:361113 (e-PCR) Links:UniSTS:156732 + SHGC-33499 (e-PCR) Links:UniSTS:23613 + GDB:361120 (e-PCR) Links:UniSTS:156733 + GDB:361125 (e-PCR) Links:UniSTS:156734 + GDB:361128 (e-PCR) Links:UniSTS:156735 + GDB:361131 (e-PCR) Links:UniSTS:156736 + Cdh1 (e-PCR), detects polymorphism Links:UniSTS:472904 + RH64967 (e-PCR) Links:UniSTS:89433 + CDH1_96.2 (e-PCR) Links:UniSTS:277087 + D1S1423 (e-PCR) Links:UniSTS:149619 + RH68244 (e-PCR) Links:UniSTS:1912 + RH64971 (e-PCR) Links:UniSTS:91522 + STS-T85105 (e-PCR) Links:UniSTS:9091 + RH91417 (e-PCR) Links:UniSTS:88196 + PMC134726P1 (e-PCR) Links:UniSTS:270747 + A008N17 (e-PCR) Links:UniSTS:11680 + PMC135805P1 (e-PCR) Links:UniSTS:270774 + PMC135805P2 (e-PCR) Links:UniSTS:270775 + PMC135805P3 (e-PCR) Links:UniSTS:270776 + PMC135805P4 (e-PCR) Links:UniSTS:270777 + PMC135805P5 (e-PCR) Links:UniSTS:270778 + RH65826 (e-PCR) Links:UniSTS:19434 + SHGC-149254 (e-PCR) Links:UniSTS:176889 + + +Homology + Homologs of the CDH1 gene + The CDH1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. + Orthologs from Annotation Pipeline (/gene/?Term=ortholog_gene_999[group]): + Orthologs + +Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA) + +Function GO ID Evidence +------------------------------------------------------------------------------------------------- +enables GTPase activating protein bindin... GO:0000000 PMID: 20116244 +enables ankyrin binding GO:0000000 PMID: 17620337 +enables beta-catenin binding GO:0000000 PMID: 17620337 +enables cadherin binding GO:0000000 PMID: 25468996 +enables cadherin binding GO:0000000 PMID: 21873635 +enables calcium ion binding GO:0000000 PMID: 21873635 +enables cell adhesion molecule binding GO:0000000 PMID: 21724833 +enables cell adhesion molecule binding GO:0000000 PMID: 16338932 +enables gamma-catenin binding GO:0000000 PMID: 1639850 +enables identical protein binding GO:0000000 PMID: 19114658,19646884,21300292,23112161,24725409 +enables protein binding GO:0000000 PMID: 10725230,11401320,11790773,12526809,15695390,16212417,16983094,17220478,17274640,17715295,18093941,18593713,19016843,19038973,19732724,19822757,20086044,21685945,22056988,22158051,22252131,22750944,23086448,24189400,24424122,24658140,25241761,25344754,31473225,31980649,32814053,34591612 +enables protein tyrosine kinase binding GO:0000000 - + +Processs GO ID Evidence +------------------------------------------------------------------------------------------------- +involved_in adherens junction organizati... GO:0000000 PMID: 21873635 +involved_in adherens junction organizati... GO:0000000 PMID: 21724833 +involved_in calcium-dependent cell-cell ... GO:0000000 PMID: 21873635 +involved_in cell morphogenesis GO:0000000 PMID: 21873635 +involved_in cell-cell adhesion GO:0000000 PMID: 16338932,18593713 +involved_in cell-cell adhesion mediated ... GO:0000000 PMID: 21873635 +involved_in cell-cell junction assembly GO:0000000 PMID: 21873635 +involved_in cellular response to indole-... GO:0000000 PMID: 10868478 +involved_in cellular response to lithium... GO:0000000 PMID: 12937339 +involved_in homophilic cell adhesion via... GO:0000000 PMID: 8033105,16338932 +involved_in multicellular organism devel... GO:0000000 PMID: 21873635 +involved_in negative regulation of axon ... GO:0000000 - +involved_in negative regulation of cell ... GO:0000000 PMID: 16882694 +involved_in negative regulation of cell-... GO:0000000 PMID: 19653274 +involved_in neuron projection developmen... GO:0000000 - +involved_in pituitary gland development GO:0000000 - +involved_in positive regulation of DNA-t... GO:0000000 PMID: 16338932 +involved_in positive regulation of prote... GO:0000000 PMID: 16338932 +involved_in protein localization to plas... GO:0000000 PMID: 17620337 +involved_in protein localization to plas... GO:0000000 PMID: 20859650 +involved_in regulation of gene expressio... GO:0000000 PMID: 19403558 +involved_in regulation of protein catabo... GO:0000000 - +involved_in response to Gram-positive ba... GO:0000000 - +involved_in response to toxic substance GO:0000000 - +involved_in response to xenobiotic stimu... GO:0000000 - +involved_in synapse assembly GO:0000000 PMID: 21873635 + +Component GO ID Evidence +------------------------------------------------------------------------------------------------- +located_in actin cytoskeleton GO:0000000 PMID: 16338932 +is_active_in adherens junction GO:0000000 PMID: 21873635 +located_in adherens junction GO:0000000 PMID: 16338932,20086044,24046456 +located_in apical junction complex GO:0000000 PMID: 10460003 +part_of catenin complex GO:0000000 PMID: 21873635 +part_of catenin complex GO:0000000 PMID: 18593713 +located_in cell junction GO:0000000 PMID: 19038973,28169360 +located_in cell junction GO:0000000 PMID: 17047063 +colocalizes_with cortical actin cytoskel... GO:0000000 PMID: 24046456 +located_in cytoplasmic side of plasma me... GO:0000000 PMID: 20189993 +located_in endosome GO:0000000 - +located_in extracellular exosome GO:0000000 PMID: 23533145 +located_in extracellular region GO:0000000 - +part_of flotillin complex GO:0000000 PMID: 24046456 +located_in glutamatergic synapse GO:0000000 - +located_in lamellipodium GO:0000000 PMID: 24046456 +located_in lateral plasma membrane GO:0000000 PMID: 16338932,17620337 +located_in membrane GO:0000000 PMID: 16338932 +located_in perinuclear region of cytopla... GO:0000000 PMID: 16338932 +located_in plasma membrane GO:0000000 PMID: 28301459 +located_in plasma membrane GO:0000000 - +located_in postsynapse GO:0000000 - +located_in trans-Golgi network GO:0000000 PMID: 17620337 + +GENERAL PROTEIN INFORMATION +------------------------------------------------------------------------------------------------- +Preferred Names + cadherin-1 +Names + CAM 120/80 + E-cadherin 1 + cadherin 1, E-cadherin (epithelial) + cadherin 1, type 1, E-cadherin (epithelial) + calcium-dependent adhesion protein, epithelial + cell-CAM 120/80 + epididymis secretory sperm binding protein + epithelial cadherin + uvomorulin + +NCBI REFERENCE SEQUENCES (RefSeq) +------------------------------------------------------------------------------------------------- + +RefSeqs maintained independently of Annotated Genomes + +These reference sequences exist independently of genome builds. +These reference sequences are curated independently of the genome annotation cycle, +so their versions may not match the RefSeq versions in the current genome build. +Identify version mismatches by comparing the version of the RefSeq in this section to +the one reported in Genomic regions, transcripts, and products section above. + + Genomic + NG_008021.1 RefSeqGene + Range 5000..103249 + Download GenBank FASTA Sequence Viewer (Graphics) + + + + mRNA and Protein(s) + + NM_001317184.2 → NP_001304113.1 REVIEWEDcadherin-1 isoform 2 precursor + Description: Transcript Variant: This variant (2) lacks an a... + Source sequence(s): AB025105, AK312551, EU709494 + Consensus CDS: CCDS82005.1 + UniProtKB/TrEMBL: B3GN61 + UniProtKB/Swiss-Prot: P12830 + + Related Ensembl: ENSP00000414946.2, ENST00000422392.6 + Conserved Domains (5)summary + cd00031: + Location:158 - 258 + CA_like; Cadherin repeat-like domain + cd11304: + Location:431 - 530 + Cadherin_repeat; Cadherin tandem repeat domain + pfam00028: + Location:537 - 625 + Cadherin; Cadherin domain + pfam01049: + Location:680 - 816 + Cadherin_C; Cadherin cytoplasmic region + pfam08758: + Location:27 - 116 + Cadherin_pro; Cadherin prodomain like + + NM_001317185.2 → NP_001304114.1 REVIEWEDcadherin-1 isoform 3 + Description: Transcript Variant: This variant (3) uses an al... + Source sequence(s): AB025106, AC099314, AK312551, EU709494 + UniProtKB/TrEMBL: B3GN61 + UniProtKB/Swiss-Prot: P12830 + UniProtKB/TrEMBL: Q9UII7 + + Conserved Domains (3)summary + cd11304: + Location:3 - 75 + Cadherin_repeat; Cadherin tandem repeat domain + pfam00028: + Location:82 - 170 + Cadherin; Cadherin domain + pfam01049: + Location:225 - 361 + Cadherin_C; Cadherin cytoplasmic region + + NM_001317186.2 → NP_001304115.1 REVIEWEDcadherin-1 isoform 4 + Description: Transcript Variant: This variant (4) lacks an e... + Source sequence(s): AK312551, BC144283, EU709494 + UniProtKB/TrEMBL: B3GN61 + UniProtKB/Swiss-Prot: P12830 + + Conserved Domains (1)summary + pfam01049: + Location:83 - 224 + Cadherin_C; Cadherin cytoplasmic region + + NM_004360.5 → NP_004351.1 REVIEWEDcadherin-1 isoform 1 preproprotein + + See proteins identical to NP_004351.1 at http://130.14.22.106/ipg/NP_004351.1/ + + Description: Transcript Variant: This variant (1) encodes th... + Source sequence(s): AK290012, AK312551, EU709494 + Consensus CDS: CCDS10869.1 + UniProtKB/TrEMBL: A0A0U2ZQU7 + UniProtKB/TrEMBL: B3GN61 + UniProtKB/Swiss-Prot: P12830 + UniProtKB/Swiss-Prot: Q9UII8 + + Related Ensembl: ENSP00000261769.4, ENST00000261769.10 + Conserved Domains (5)summary + cd00031: + Location:158 - 258 + CA_like; Cadherin repeat-like domain + cd11304: + Location:492 - 591 + Cadherin_repeat; Cadherin tandem repeat domain + pfam01049: + Location:738 - 879 + Cadherin_C; Cadherin cytoplasmic region + pfam08758: + Location:27 - 116 + Cadherin_pro; Cadherin prodomain like + cl09101: + Location:598 - 686 + E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either th... + +RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_03 +The following sections contain reference sequences that belong to a specific genome build. +This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which +this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both +reference and alternate assemblies. Model RNAs and proteins are also reported here. + +Reference GRCh38.p14 Primary Assembly + + Genomic + NC_000016.10 Reference GRCh38.p14 Primary Assembly + Range 68737291..68835536 + Download GenBank FASTA Sequence Viewer (Graphics) + +Alternate T2T-CHM13v2.0 + + Genomic + NC_060940.1 Alternate T2T-CHM13v2.0 + Range 74533466..74631803 + Download GenBank FASTA Sequence Viewer (Graphics) + + + +RELATED SEQUENCES +------------------------------------------------------------------------------------------------- + +Nucleotide Protein +------------------------------------------------------------------------------------------------- +genomic AC099314.3(177204..179065) None +genomic AH003504.2 None +genomic AH006175.2 None +genomic AH007361.2 AAD14108.1 +genomic AY341818.1 None +genomic CH471092.1 EAW83242.1 + EAW83243 + EAW83244 + EAW83245 +genomic CP068262.2(74533467..74631804) None +genomic D49685.1 BAA08537.1 +genomic DQ090940.1 AAY68225.1 +genomic DQ335132.1 None +genomic GU371438.1 ADC53120.1 +genomic JC597161.1 CEF39405.1 +genomic KP232928.1 AKC34897.1 +genomic KT355487.1 ALS87660.1 +genomic KT820428.1 AMO26215.1 +genomic KX271351.1 None +genomic L34545.1 AAA21764.1 +genomic LC750329.1 BDW80550.1 +genomic LC750330.1 BDW80551.1 +genomic LC750331.1 BDW80552.1 +genomic LC750332.1 BDW80553.1 +genomic LC750333.1 BDW80554.1 +genomic LC750334.1 BDW80555.1 +genomic LC750335.1 BDW80556.1 +genomic LC750336.1 BDW80557.1 +genomic LC750337.1 BDW80558.1 +genomic LC750338.1 BDW80559.1 +genomic LC750339.1 BDW80560.1 +genomic MG660829.1 AYN44076.1 +genomic MK503194.1 None +genomic MN080224.1 QHW05978.1 +genomic Z35402.1 CAA84586.1 +genomic Z35403.1(15..158) None +genomic Z35404.1(15..170) None +genomic Z35405.1(15..159) None +genomic Z35406.1(15..190) None +genomic Z35407.1(15..143) None +genomic Z35408.1(15..197) None +genomic Z35409.1(15..259) None +genomic Z35410.1(15..160) None +genomic Z35411.1(15..239) None +genomic Z35412.1(15..242) None +genomic Z35413.1(15..145) None +genomic Z35414.1(15..158) None +genomic Z35415.1(15..2259) None +mRNA AB025105.1 BAA88956.1 +mRNA AB025106.1 BAA88957.1 +mRNA AI890107.1 None +mRNA AK290012.1 BAF82701.1 +mRNA AK297913.1 BAG60232.1 +mRNA AK309703.1 None +mRNA AK311198.1 None +mRNA AK312551.1 BAG35448.1 +mRNA BC013851.1 None +mRNA BC141838.1 AAI41839.1 +mRNA BC144283.1 None +mRNA BC146662.1 AAI46663.1 +mRNA EU709494.1 ACD87624.1 +mRNA GQ891411.1 ADO22273.1 +mRNA L08599.1 AAA61259.1 +mRNA MZ047303.1 UIW38054.1 +mRNA X12790.1 CAA31279.1 +mRNA X52279.1 CAA36522.1 +mRNA Z13009.1 CAA78353.1 +mRNA Z18923.1 CAA79356.1 + +Protein Accession Links +------------------------------------------------------------------------------------------------- +P12830.3 GenPept(/protein/399166) UniProtKB/Swiss-Prot:P12830 + +GENE LINKOUT +------------------------------------------------------------------------------------------------- +The following LinkOut(www.ncbi.nlm.nih.gov/projects/linkout/index.html) resources +are supplied by external providers. These providers are responsible for +maintaining the links. + +Chemical Information + (Free resource) (free) Interologous Interaction Database + Interologous Interaction Database + (Order form) MilliporeSigma + CDH1 productsCDH1 products + +Medical + (Free resource) (free) MedlinePlus Health Information + CDH1 geneCDH1 gene + +Molecular Biology Databases + (Free resource) (free) Bgee database + CDH1 gene expressionCDH1 gene expression + (Free resource) (free) BioGPS + BioGPS + (Free resource) (free) BioGRID Open Repository of CRISPR Screens (ORCS) + BioGRID CRISPR Screen Phenotypes (47 hits/1173 screens)BioGRID CRISPR Screen Phenotypes (47 hits/1173 screens) + (Free resource) (free) CREB Target Gene Database + CREB Target Gene Database + (Free resource) (Free registration required) (free) Creative Biogene + cadherin 1, type 1, E-cadherin (epithelial)cadherin 1, type 1, E-cadherin (epithelial) + (Free resource) (free) Domain Mapping of Disease Mutations + CDH1CDH1 + (Free resource) (free) Eukaryotic Promoter Database + CDH1_1CDH1_1 + (Order form) GenScript latest version of gene cDNA ORF Clone + GenScript latest version of gene cDNA ORF Clone + (Free resource) (free) GeneNetwork + Records for gene expression in HumanRecords for gene expression in Human + (Free resource) (free) Genevisible + CDH1CDH1 + (Free resource) (free) GlyGen glycoinformatics resource + GlyGen glycoinformatics resource + (Free resource) (Free registration required) (free) Human Gene Mutation Database + Human Gene Mutation Database + (Free resource) (free) Human eFP Browser + Human eFP BrowserHuman eFP BrowserHuman eFP Browser + Ingenuity Pathways Analysis + Ingenuity Pathways Analysis + (Free resource) (free) InnateDB + InnateDB + (Free resource) (free) InterMine + InterMine + (Free resource) (free) Kyoto Encyclopedia of Genes and Genomes + Kyoto Encyclopedia of Genes and Genomes + (Free resource) (free) LSDB from Gene + CDH1 @ LOVDCDH1 @ LOVD + (Free resource) (free) OMA Browser: Orthologous MAtrix + OMA Browser: Orthologous MAtrixOMA Browser: Orthologous MAtrix + (Free resource) (free) OrthoDB catalog of orthologs + OrthologsOrthologs + (Free resource) (free) Pharmacogenomics Knowledge Base + Annotated Pharmacogenomic Information for CDH1 [PharmGKB]Annotated Pharmacogenomic Information for CDH1 [PharmGKB] + (Free resource) (free) PhosphoSitePlus + PhosphoSitePlus® - comprehensive post-translational modification resourcePhosphoSitePlus® - comprehensive post-translational modification resource + (Free resource) (free) Protein Ontology Consortium + Protein Ontology Consortium + (Free resource) (free) The Gene Wiki + The Gene Wiki + (Free resource) (free) The Weizmann Institute of Science GeneCards and MalaCards databases + GeneCard for CDH1GeneCard for CDH1 + (Free resource) (free) Vertebrate Genome Annotation (VEGA) database + Vertebrate Genome Annotation (VEGA) database + (Free resource) (free) iRefWeb - iRefIndex release 9.0 - Consolidated Interactome + iRefWeb - iRefIndex release 9.0 - Consolidated Interactome + +Research Materials + (Order form) Addgene Non-profit plasmid repository + Get Plasmids - AddgeneGet Plasmids - Addgene + ExactAntigen/Labome + reagent reviewreagent reviewreagentsreagents + (Order form) GeneCopoeia Inc. + Order shRNA clonesOrder shRNA clonesOrder promoter cloneOrder promoter cloneOrder full-length ORF cloneOrder full-length ORF clone + (Order form) GeneTex Inc + Find Quality AntibodiesFind Quality Antibodies + LifeSpan BioSciences, Inc. + LSBio CDH1 / E Cadherin ProteinsLSBio CDH1 / E Cadherin ProteinsLSBio CDH1 / E Cadherin Elisa KitsLSBio CDH1 / E Cadherin Elisa KitsLSBio CDH1 / E Cadherin AntibodiesLSBio CDH1 / E Cadherin Antibodies + (Order form) NITE Biological Resource Center + Human cDNA clones used in NEDO Project / AK297913Human cDNA clones used in NEDO Project / AK297913Human cDNA clones used in NEDO Project / AK309703Human cDNA clones used in NEDO Project / AK309703Human cDNA clones used in NEDO Project / AK311198Human cDNA clones used in NEDO Project / AK311198 + (Order form) Sino Biological Inc. + E-Cadherin / CDH1 / E-cad / CD324 Antibody (PE), Mouse MAbE-Cadherin / CDH1 / E-cad / CD324 Antibody (PE), Mouse MAbE-Cadherin / CDH1 / E-cad / CD324 Antibody, Rabbit MAbE-Cadherin / CDH1 / E-cad / CD324 Antibody, Rabbit MAbE-Cadherin / CDH1 / E-cad / CD324 Antibody, Rabbit MAbE-Cadherin / CDH1 / E-cad / CD324 Antibody, Rabbit MAb + +Tools + (Free resource) (free) GeneMANIA + GeneMANIA \ No newline at end of file