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b/GeneID_6794.txt |
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STK11 serine/threonine kinase 11[Homo sapiens] |
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Gene ID: 6794, updated on 20-Apr-2023 |
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SUMMARY |
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Official Symbol: STK11 (provided by HGNC) |
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Official full name: serine/threonine kinase 11 (provided by HGNC) |
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Primary source: HGNC:HGNC:11389 |
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See related: Ensembl:ENSG00000118046; MIM:602216; AllianceGenome:HGNC:11389 |
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Gene type: protein coding |
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RefSeq status: REVIEWED |
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Organism: Homo sapiens |
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Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; |
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Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo |
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Also known as: PJS; LKB1; hLKB1 |
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Summary: The protein encoded by this gene is a serine/threonine kinase that regulates cell |
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polarity and energy metabolism and functions as a tumor suppressor. Mutations in |
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this gene have been associated with the autosomal dominant Peutz-Jeghers |
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syndrome, as well as with skin, pancreatic, and testicular cancers. [provided by |
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RefSeq, May 2022] |
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Orthologsall (/gene/?Term=ortholog_gene_6794[group]), mouse (https://www.ncbi.nlm.nih.gov/gene/20869) |
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GENOMIC CONTEXT |
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Location: 19p13.3 |
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Annotation release Status Assembly Chromosome Location |
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RS_2023_03 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (1205778..1228431) |
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RS_2023_03 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (1174325..1196989) |
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105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (1205777..1228430) |
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Exont count: 12 |
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BIBLIOGRAPHY |
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Related Articles in PubMed |
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1. The liver kinase B1 supports mammary epithelial morphogenesis by inhibiting |
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critical factors that mediate epithelial-mesenchymal transition. Tzavlaki K, . J |
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Cell Physiol, 2023 Apr, PMID 36791282. |
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2. LKB1 Loss Assessed by Immunohistochemistry as a Prognostic Marker to First-Line |
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Therapy in Advanced Non-Small-Cell Lung Cancer. Avilés-Salas A, . Curr Oncol, |
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2022 Dec 26, PMID 36661676., Free PMC Article(s): PMC9857995 |
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3. STK11 Inactivation Predicts Rapid Recurrence in Inoperable Early-Stage |
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Non-Small-Cell Lung Cancer. Katipally RR, . JCO Precis Oncol, 2023 Jan, PMID |
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36603171. |
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4. A novel missense mutation of the STK11 gene in a Chinese family with |
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Peutz-Jeghers syndrome. Yu Z, . BMC Gastroenterol, 2022 Dec 22, PMID 36550395., Free PMC Article(s): PMC9784088 |
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5. Liver kinase B1 in exosomes inhibits immune checkpoint programmed death ligand 1 |
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and metastatic progression of intrahepatic cholangiocarcinoma. Liu Z, . Oncol |
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Rep, 2022 Sep, PMID 35856436., Free PMC Article(s): PMC9350976 |
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6. LKB1 is the gatekeeper of carotid body chemosensing and the hypoxic ventilatory |
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response. MacMillan S, . Commun Biol, 2022 Jun 29, PMID 35768580., Free PMC Article(s): PMC9243028 |
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<pre> |
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PHENOTYPES |
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Review eQTL and phenotype association data in this region using PheGenI |
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http://www.ncbi.nlm.nih.gov/gap/PheGenI?chr=19&from=1205777&fromto=1205777+1228430&tab=0 |
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Professional guidelines |
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Professional guideline |
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ACMG 2013 |
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The ACMG recommends that laboratories performing clinical sequencing seek and report mutations in STK11 that are pathogenic or expected to be pathogenic. |
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Guideline(http://www.acmg.net/docs/ACMG_Releases_Highly-Anticipated_Recommendations_on_Incidental_Findings_in_Clinical_Exome_and_Genome_Sequencing.pdf) |
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PubMed(/pubmed/23788249) |
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Associated conditions |
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Description Tests |
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Carcinoma of pancreas |
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MedGen: C0235974 OMIM: 260350 GeneReviews: <span>Not available</span> |
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Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects. |
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GeneReviews: <span>Not available</span> |
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Genome-wide association study of Alzheimer's disease with psychotic symptoms. |
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GeneReviews: <span>Not available</span> |
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Germ cell tumor of testis |
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MedGen: C1336708 OMIM: 273300 GeneReviews: <span>Not available</span> |
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Melanoma, cutaneous malignant, susceptibility to, 1 |
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MedGen: C1835047 OMIM: 155600 GeneReviews: <span>Not available</span> |
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Peutz-Jeghers syndrome |
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MedGen: C0031269 OMIM: 175200 GeneReviews: Peutz-Jeghers Syndrome |
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Copy number response |
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Copy number response |
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Triplosensitivity |
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No evidence available (Last evaluated 2021-11-10) |
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103 |
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ClinGen Genome Curation Page(https://www.ncbi.nlm.nih.gov/projects/dbvar/ISCA/isca_gene.cgi?sym=STK11)Haploinsufficency |
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Sufficient evidence for dosage pathogenicity (Last evaluated 2021-11-10) |
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106 |
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ClinGen Genome Curation Page(https://www.ncbi.nlm.nih.gov/projects/dbvar/ISCA/isca_gene.cgi?sym=STK11) |
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PubMed(/pubmed/20623358,23892522,2563227,28231849)</pre> |
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VARIATION |
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See variants in ClinVar, http://130.14.22.58/sites/gene/clinvar/?term=STK11[gene] |
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See studies and variants in dbVar, http://130.14.22.58/sites/gene |
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See Variation Viewer (GRCh37.p13), http://130.14.22.58/sites/gene/variation/view/?q=6794[geneid]&assm=GCF_000001405.25 |
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See Variation Viewer (GRCh38), http://130.14.22.58/sites/gene/variation/view/?q=6794[geneid]<pre/><pre> |
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Genotypes |
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See SNP Geneview Report, http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2FSNP%2Fsnp_ref.cgi%3FlocusId%3D6794 |
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See 1000 Genomes Browser (GCF_000001405.25), http://130.14.22.58/sites/gene/variation/tools/1000genomes/?q=6794[geneid]&assm=GCF_000001405.25</pre> |
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INTERACTION |
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Description of Gene Interaction table |
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Product Interactant Other Gene Complex Source Pubs |
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LKB1 phosphorylates MARK4. |
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NP_000446.1 NP_113605.2 MARK4 BIND PMID: 14676191 |
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LKB1 interacts with AMPK-alpha. |
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NP_000446.1 NP_006243.2 PRKAA2 BIND PMID: 14985505 |
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LKB1 autophosphorylates itself. |
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NP_000446.1 NP_000446.1 STK11 BIND PMID: 14676191 |
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LKB1 phosphorylates PAPK. |
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NP_000446.1 NP_061041.2 STRADB BIND PMID: 14676191 |
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Q15831 Q13315 ATM HPRD PMID: 12234250,11853558 |
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Q15831 Q9Y376 CAB39 HPRD PMID: 14676191 |
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Q15831 Q16543 CDC37 HPRD PMID: 12489981 |
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Q15831 Q9P0L2 MARK1 HPRD PMID: 14976552,14517247 |
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Q15831 Q7KZI7 MARK2 HPRD PMID: 14976552 |
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Q15831 Q96L34 MARK4 HPRD PMID: 14676191 |
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Q15831 Q9Y3A3 MOB4 HPRD PMID: 16169070 |
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Q15831 Q8TEW0 PARD3 HPRD PMID: 14676191 |
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Q15831 P54646 PRKAA2 HPRD PMID: 10642499 |
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Q15831 P17612 PRKACA HPRD PMID: 11853558,11297520 |
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Q15831 P60484 PTEN HPRD PMID: 15987703 |
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Q15831 P51812 RPS6KA3 HPRD PMID: 11853558,11297520 |
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Q15831 O75582 RPS6KA5 HPRD PMID: 11297520 |
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Q15831 P23443 RPS6KB1 HPRD PMID: 11853558,11297520 |
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Q15831 P51532 SMARCA4 HPRD PMID: 11445556 |
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Q15831 Q9NRH2 SNRK HPRD PMID: 15733851 |
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Q15831 Q15831 STK11 HPRD PMID: 11668633 |
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Q15831 LKB1 interacting protein 1 STK11IP HPRD PMID: 11741830 |
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Q15831 Protein kinase LYK5 STRADA HPRD PMID: 12805220 |
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Q15831 Q9C0K7 STRADB HPRD PMID: 14676191 |
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Q15831 TNFAIP3 interacting protein 2 TNIP2 HPRD PMID: 12595760 |
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Q15831 P04637 TP53 HPRD PMID: 11430832 |
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Affinity Capture-MS |
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BioGRID:112670 BioGRID:126860 A2ML1 BioGRID PMID: 33961781 |
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FRET |
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BioGRID:112670 BioGRID:131028 ABCB5 BioGRID PMID: 28205554 |
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Affinity Capture-MS |
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BioGRID:112670 BioGRID:116784 ABRAXAS2 BioGRID PMID: 33961781,28514442 |
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Two-hybrid |
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BioGRID:112670 BioGRID:119283 ADIPOR1 BioGRID PMID: 25640309 |
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168 |
Affinity Capture-MS |
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BioGRID:112670 BioGRID:120419 AGGF1 BioGRID PMID: 33961781 |
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170 |
Affinity Capture-MS |
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BioGRID:112670 BioGRID:124393 AJUBA BioGRID PMID: 34591612 |
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172 |
Affinity Capture-MS |
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BioGRID:112670 BioGRID:115445 AKAP9 BioGRID PMID: 33961781 |
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FRET; Two-hybrid |
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BioGRID:112670 BioGRID:106710 AKT1 BioGRID PMID: 28205554,24412244 |
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Affinity Capture-MS |
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BioGRID:112670 BioGRID:111790 ALDH18A1 BioGRID PMID: 34591612 |
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Two-hybrid |
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179 |
BioGRID:112670 BioGRID:106730 ALDOB BioGRID PMID: 24412244 |
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180 |
Affinity Capture-MS |
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BioGRID:112670 BioGRID:106775 AMY1C BioGRID PMID: 33961781 |
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Two-hybrid |
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183 |
BioGRID:112670 BioGRID:115795 ANP32B BioGRID PMID: 24412244 |
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184 |
Affinity Capture-MS |
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BioGRID:112670 BioGRID:106798 ANXA1 BioGRID PMID: 33961781 |
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186 |
Affinity Capture-MS |
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BioGRID:112670 BioGRID:575558 ANXA8 BioGRID PMID: 33961781 |
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188 |
Affinity Capture-Western |
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BioGRID:112670 BioGRID:107587 AP2M1 BioGRID PMID: 20368287 |
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Reconstituted Complex |
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BioGRID:112670 BioGRID:106848 APP BioGRID PMID: 21832049 |
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FRET |
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BioGRID:112670 BioGRID:106864 ARAF BioGRID PMID: 28205554 |
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Two-hybrid |
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BioGRID:112670 BioGRID:106879 ARG2 BioGRID PMID: 25640309 |
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Negative Genetic |
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BioGRID:112670 BioGRID:128219 ARID2 BioGRID PMID: 35559673 |
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FRET |
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BioGRID:112670 BioGRID:106898 ARNT BioGRID PMID: 28205554 |
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Negative Genetic |
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201 |
BioGRID:112670 BioGRID:121948 ATG101 BioGRID PMID: 35559673 |
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Phenotypic Suppression |
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203 |
BioGRID:112670 BioGRID:115787 ATG7 BioGRID PMID: 33226137 |
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204 |
Negative Genetic |
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205 |
BioGRID:112670 BioGRID:122518 ATG9A BioGRID PMID: 35559673 |
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206 |
Affinity Capture-Western |
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207 |
BioGRID:112670 BioGRID:106962 ATM BioGRID PMID: 15713674 |
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208 |
FRET |
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209 |
BioGRID:112670 BioGRID:112666 AURKA BioGRID PMID: 28205554 |
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210 |
Two-hybrid |
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211 |
BioGRID:112670 BioGRID:198131 Ap2m1 BioGRID PMID: 20368287 |
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212 |
Affinity Capture-MS |
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213 |
BioGRID:112670 BioGRID:118855 BABAM1 BioGRID PMID: 33961781 |
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214 |
Negative Genetic |
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215 |
BioGRID:112670 BioGRID:113647 BAG6 BioGRID PMID: 35559673 |
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216 |
Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid |
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217 |
BioGRID:112670 BioGRID:113911 BAP1 BioGRID PMID: 32819560 |
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218 |
Two-hybrid |
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219 |
BioGRID:112670 BioGRID:120182 BCAS3 BioGRID PMID: 25640309 |
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Negative Genetic |
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221 |
BioGRID:112670 BioGRID:115118 BCLAF1 BioGRID PMID: 35559673 |
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222 |
FRET |
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223 |
BioGRID:112670 BioGRID:114226 BECN1 BioGRID PMID: 28205554 |
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224 |
Negative Genetic |
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225 |
BioGRID:112670 BioGRID:121521 BIRC6 BioGRID PMID: 35559673 |
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226 |
Affinity Capture-MS |
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227 |
BioGRID:112670 BioGRID:126647 BPIFA2 BioGRID PMID: 33961781 |
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228 |
Affinity Capture-MS |
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229 |
BioGRID:112670 BioGRID:123248 BPIFB2 BioGRID PMID: 33961781 |
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230 |
FRET |
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231 |
BioGRID:112670 BioGRID:107141 BRAF BioGRID PMID: 28205554 |
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232 |
Negative Genetic |
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233 |
BioGRID:112670 BioGRID:122599 BRCC3 BioGRID PMID: 35559673 |
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234 |
Negative Genetic |
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235 |
BioGRID:112670 BioGRID:122430 BRD9 BioGRID PMID: 35559673 |
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236 |
Negative Genetic |
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237 |
BioGRID:112670 BioGRID:123841 BRIP1 BioGRID PMID: 35559673 |
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238 |
Negative Genetic |
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239 |
BioGRID:112670 BioGRID:107160 BTK BioGRID PMID: 35559673 |
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240 |
Affinity Capture-MS |
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241 |
BioGRID:112670 BioGRID:126409 C5orf24 BioGRID PMID: 33961781,28514442 |
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242 |
Affinity Capture-MS |
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243 |
BioGRID:112670 BioGRID:131603 C6orf58 BioGRID PMID: 33961781 |
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244 |
Negative Genetic |
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245 |
BioGRID:112670 BioGRID:124367 C8orf76 BioGRID PMID: 35559673 |
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246 |
Affinity Capture-MS |
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247 |
BioGRID:112670 BioGRID:107220 CA6 BioGRID PMID: 33961781 |
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248 |
Affinity Capture-MS; Affinity Capture-Western; Co-localization |
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249 |
BioGRID:112670 BioGRID:119696 CAB39 BioGRID PMID: 35271311,34591612,33961781,32707033,31554794,31217475,28514442,25852190,25241761,20562859,15561763,14676191 |
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250 |
Affinity Capture-MS |
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251 |
BioGRID:112670 BioGRID:123552 CAB39L BioGRID PMID: 33961781,28514442,26186194,20562859 |
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252 |
Two-hybrid |
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253 |
BioGRID:112670 BioGRID:107256 CALM2 BioGRID PMID: 25640309 |
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254 |
Negative Genetic |
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255 |
BioGRID:112670 BioGRID:127632 CAMSAP1 BioGRID PMID: 35559673 |
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256 |
FRET |
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257 |
BioGRID:112670 BioGRID:117156 CBLC BioGRID PMID: 28205554 |
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258 |
Affinity Capture-MS |
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259 |
BioGRID:112670 BioGRID:122267 CCDC136 BioGRID PMID: 25852190 |
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260 |
Two-hybrid |
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261 |
BioGRID:112670 BioGRID:1527673 CCDC180 BioGRID PMID: 24412244 |
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262 |
FRET |
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263 |
BioGRID:112670 BioGRID:107334 CCND2 BioGRID PMID: 28205554 |
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264 |
FRET |
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265 |
BioGRID:112670 BioGRID:107338 CCNE1 BioGRID PMID: 28205554 |
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266 |
FRET |
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267 |
BioGRID:112670 BioGRID:107398 CD44 BioGRID PMID: 28205554 |
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268 |
Two-hybrid |
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269 |
BioGRID:112670 BioGRID:114125 CDC14B BioGRID PMID: 24412244 |
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270 |
Affinity Capture-MS; Affinity Capture-Western |
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271 |
BioGRID:112670 BioGRID:116312 CDC37 BioGRID PMID: 34591612,33961781,32707033,21860411,20562859,14676191,14668798 |
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272 |
FRET |
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273 |
BioGRID:112670 BioGRID:107454 CDK4 BioGRID PMID: 28205554 |
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274 |
FRET |
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275 |
BioGRID:112670 BioGRID:107456 CDK6 BioGRID PMID: 28205554 |
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276 |
FRET |
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277 |
BioGRID:112670 BioGRID:107463 CDKN2A BioGRID PMID: 28205554 |
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278 |
FRET |
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279 |
BioGRID:112670 BioGRID:107464 CDKN2B BioGRID PMID: 28205554 |
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280 |
FRET |
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281 |
BioGRID:112670 BioGRID:107465 CDKN2C BioGRID PMID: 28205554 |
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282 |
Two-hybrid |
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283 |
BioGRID:112670 BioGRID:107500 CFL2 BioGRID PMID: 25640309 |
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284 |
Affinity Capture-MS |
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285 |
BioGRID:112670 BioGRID:114729 COPS2 BioGRID PMID: 34591612,32707033 |
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286 |
Affinity Capture-MS |
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287 |
BioGRID:112670 BioGRID:114103 COPS3 BioGRID PMID: 34591612,33961781,32707033,25852190 |
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288 |
Affinity Capture-MS |
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289 |
BioGRID:112670 BioGRID:119324 COPS4 BioGRID PMID: 34591612,32707033,25852190 |
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290 |
Affinity Capture-MS; Affinity Capture-Western |
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291 |
BioGRID:112670 BioGRID:116183 COPS5 BioGRID PMID: 34591612,30710502 |
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292 |
Affinity Capture-MS |
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293 |
BioGRID:112670 BioGRID:116176 COPS6 BioGRID PMID: 34591612,32707033 |
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|
294 |
Affinity Capture-MS |
|
|
295 |
BioGRID:112670 BioGRID:119130 COPS7A BioGRID PMID: 34591612 |
|
|
296 |
Affinity Capture-MS |
|
|
297 |
BioGRID:112670 BioGRID:122237 COPS7B BioGRID PMID: 34591612 |
|
|
298 |
Affinity Capture-MS |
|
|
299 |
BioGRID:112670 BioGRID:116124 COPS8 BioGRID PMID: 34591612,32707033 |
|
|
300 |
Affinity Capture-MS |
|
|
301 |
BioGRID:112670 BioGRID:119069 CRNN BioGRID PMID: 33961781 |
|
|
302 |
Two-hybrid |
|
|
303 |
BioGRID:112670 BioGRID:107798 CRY2 BioGRID PMID: 25640309 |
|
|
304 |
Negative Genetic |
|
|
305 |
BioGRID:112670 BioGRID:107836 CSNK1A1 BioGRID PMID: 35559673 |
|
|
306 |
Synthetic Lethality |
|
|
307 |
BioGRID:112670 BioGRID:107841 CSNK2A1 BioGRID PMID: 27453043 |
|
|
308 |
Affinity Capture-MS |
|
|
309 |
BioGRID:112670 BioGRID:107851 CST1 BioGRID PMID: 33961781 |
|
|
310 |
Affinity Capture-MS |
|
|
311 |
BioGRID:112670 BioGRID:107852 CST2 BioGRID PMID: 33961781 |
|
|
312 |
Affinity Capture-MS |
|
|
313 |
BioGRID:112670 BioGRID:107854 CST4 BioGRID PMID: 33961781 |
|
|
314 |
Two-hybrid |
|
|
315 |
BioGRID:112670 BioGRID:107888 CTSB BioGRID PMID: 25640309 |
|
|
316 |
Affinity Capture-MS |
|
|
317 |
BioGRID:112670 BioGRID:114031 CUL2 BioGRID PMID: 34591612 |
|
|
318 |
Affinity Capture-MS |
|
|
319 |
BioGRID:112670 BioGRID:114028 CUL4B BioGRID PMID: 32707033 |
|
|
320 |
Affinity Capture-MS |
|
|
321 |
BioGRID:112670 BioGRID:115159 CUL7 BioGRID PMID: 33961781 |
|
|
322 |
Two-hybrid |
|
|
323 |
BioGRID:112670 BioGRID:107919 CYLC2 BioGRID PMID: 24412244 |
|
|
324 |
Two-hybrid |
|
|
325 |
BioGRID:112670 BioGRID:107958 CYP17A1 BioGRID PMID: 25640309 |
|
|
326 |
Two-hybrid |
|
|
327 |
BioGRID:112670 BioGRID:608722 D2HGDH BioGRID PMID: 25640309 |
|
|
328 |
FRET |
|
|
329 |
BioGRID:112670 BioGRID:107972 DACH1 BioGRID PMID: 28205554 |
|
|
330 |
Negative Genetic |
|
|
331 |
BioGRID:112670 BioGRID:121945 DHX35 BioGRID PMID: 35559673 |
|
|
332 |
Affinity Capture-MS |
|
|
333 |
BioGRID:112670 BioGRID:108095 DMBT1 BioGRID PMID: 33961781 |
|
|
334 |
Negative Genetic |
|
|
335 |
BioGRID:112670 BioGRID:108112 DNASE1 BioGRID PMID: 35559673 |
|
|
336 |
Negative Genetic |
|
|
337 |
BioGRID:112670 BioGRID:125472 DNTTIP1 BioGRID PMID: 35559673 |
|
|
338 |
Affinity Capture-MS |
|
|
339 |
BioGRID:112670 BioGRID:108164 DSG3 BioGRID PMID: 33961781 |
|
|
340 |
Affinity Capture-MS |
|
|
341 |
BioGRID:112670 BioGRID:108189 DVL2 BioGRID PMID: 28514442 |
|
|
342 |
Two-hybrid |
|
|
343 |
BioGRID:112670 BioGRID:108238 EEF1A2 BioGRID PMID: 25640309 |
|
|
344 |
Affinity Capture-Western |
|
|
345 |
BioGRID:112670 BioGRID:108286 EIF2B1 BioGRID PMID: 20368287 |
|
|
346 |
Affinity Capture-MS |
|
|
347 |
BioGRID:112670 BioGRID:114423 ENDOU BioGRID PMID: 33961781 |
|
|
348 |
FRET |
|
|
349 |
BioGRID:112670 BioGRID:108288 EPHA2 BioGRID PMID: 28205554 |
|
|
350 |
FRET |
|
|
351 |
BioGRID:112670 BioGRID:108376 ERBB2 BioGRID PMID: 28205554 |
|
|
352 |
Two-hybrid |
|
|
353 |
BioGRID:112670 BioGRID:118096 ERLEC1 BioGRID PMID: 25640309 |
|
|
354 |
Affinity Capture-Western; Biochemical Activity; Two-hybrid |
|
|
355 |
BioGRID:112670 BioGRID:108419 ETV4 BioGRID PMID: 21150337,16912160 |
|
|
356 |
Affinity Capture-MS |
|
|
357 |
BioGRID:112670 BioGRID:108426 EVPL BioGRID PMID: 33961781 |
|
|
358 |
Two-hybrid |
|
|
359 |
BioGRID:112670 BioGRID:229070 Eif2b1 BioGRID PMID: 20368287 |
|
|
360 |
Two-hybrid |
|
|
361 |
BioGRID:112670 BioGRID:116659 FAIM2 BioGRID PMID: 25640309 |
|
|
362 |
Negative Genetic |
|
|
363 |
BioGRID:112670 BioGRID:123086 FAM106A BioGRID PMID: 35559673 |
|
|
364 |
Negative Genetic |
|
|
365 |
BioGRID:112670 BioGRID:108472 FANCA BioGRID PMID: 35559673 |
|
|
366 |
Negative Genetic |
|
|
367 |
BioGRID:112670 BioGRID:108483 FANCF BioGRID PMID: 35559673 |
|
|
368 |
Two-hybrid |
|
|
369 |
BioGRID:112670 BioGRID:108497 FBP1 BioGRID PMID: 24412244 |
|
|
370 |
Two-hybrid |
|
|
371 |
BioGRID:112670 BioGRID:114317 FBP2 BioGRID PMID: 24412244 |
|
|
372 |
Affinity Capture-Western |
|
|
373 |
BioGRID:112670 BioGRID:126870 FBXL14 BioGRID PMID: 29601127 |
|
|
374 |
Affinity Capture-Western; Co-localization |
|
|
375 |
BioGRID:112670 BioGRID:117649 FBXO22 BioGRID PMID: 31217475 |
|
|
376 |
Negative Genetic |
|
|
377 |
BioGRID:112670 BioGRID:127320 FBXO41 BioGRID PMID: 35559673 |
|
|
378 |
Negative Genetic |
|
|
379 |
BioGRID:112670 BioGRID:119962 FBXO42 BioGRID PMID: 35559673 |
|
|
380 |
Negative Genetic |
|
|
381 |
BioGRID:112670 BioGRID:116887 FBXW11 BioGRID PMID: 35559673 |
|
|
382 |
Affinity Capture-MS |
|
|
383 |
BioGRID:112670 BioGRID:117645 FBXW8 BioGRID PMID: 33961781 |
|
|
384 |
FRET |
|
|
385 |
BioGRID:112670 BioGRID:108555 FGFR4 BioGRID PMID: 28205554 |
|
|
386 |
Affinity Capture-MS |
|
|
387 |
BioGRID:112670 BioGRID:108578 FKBP4 BioGRID PMID: 34591612 |
|
|
388 |
Affinity Capture-MS |
|
|
389 |
BioGRID:112670 BioGRID:108579 FKBP5 BioGRID PMID: 34591612,33961781,32707033,28514442,25852190,20562859,14676191 |
|
|
390 |
Affinity Capture-MS |
|
|
391 |
BioGRID:112670 BioGRID:108601 FLG BioGRID PMID: 33961781 |
|
|
392 |
Affinity Capture-MS |
|
|
393 |
BioGRID:112670 BioGRID:122669 FYCO1 BioGRID PMID: 33961781 |
|
|
394 |
FRET |
|
|
395 |
BioGRID:112670 BioGRID:119489 FZR1 BioGRID PMID: 28205554 |
|
|
396 |
Affinity Capture-MS |
|
|
397 |
BioGRID:112670 BioGRID:108887 GARS1 BioGRID PMID: 34591612 |
|
|
398 |
Affinity Capture-MS |
|
|
399 |
BioGRID:112670 BioGRID:127864 GBP6 BioGRID PMID: 33961781 |
|
|
400 |
FRET |
|
|
401 |
BioGRID:112670 BioGRID:124182 GLIS2 BioGRID PMID: 28205554 |
|
|
402 |
Two-hybrid |
|
|
403 |
BioGRID:112670 BioGRID:115325 GNPDA1 BioGRID PMID: 25640309 |
|
|
404 |
Affinity Capture-MS |
|
|
405 |
BioGRID:112670 BioGRID:109131 GPS1 BioGRID PMID: 34591612,32707033 |
|
|
406 |
FRET |
|
|
407 |
BioGRID:112670 BioGRID:109168 GRM1 BioGRID PMID: 28205554 |
|
|
408 |
Affinity Capture-Western |
|
|
409 |
BioGRID:112670 BioGRID:109187 GSK3B BioGRID PMID: 22270359 |
|
|
410 |
Negative Genetic |
|
|
411 |
BioGRID:112670 BioGRID:114937 GTPBP1 BioGRID PMID: 35559673 |
|
|
412 |
Negative Genetic |
|
|
413 |
BioGRID:112670 BioGRID:120097 GTPBP2 BioGRID PMID: 35559673 |
|
|
414 |
Affinity Capture-MS |
|
|
415 |
BioGRID:112670 BioGRID:109268 H2AX BioGRID PMID: 25852190 |
|
|
416 |
Affinity Capture-MS |
|
|
417 |
BioGRID:112670 BioGRID:109284 HAL BioGRID PMID: 33961781 |
|
|
418 |
Affinity Capture-Western; Biochemical Activity |
|
|
419 |
BioGRID:112670 BioGRID:114438 HERC2 BioGRID PMID: 27259994 |
|
|
420 |
FRET |
|
|
421 |
BioGRID:112670 BioGRID:109330 HGF BioGRID PMID: 28205554 |
|
|
422 |
FRET |
|
|
423 |
BioGRID:112670 BioGRID:109338 HIF1A BioGRID PMID: 28205554 |
|
|
424 |
Affinity Capture-MS |
|
|
425 |
BioGRID:112670 BioGRID:109345 HK1 BioGRID PMID: 34591612 |
|
|
426 |
Negative Genetic |
|
|
427 |
BioGRID:112670 BioGRID:109465 HOXC9 BioGRID PMID: 35559673 |
|
|
428 |
Two-hybrid |
|
|
429 |
BioGRID:112670 BioGRID:109501 HRAS BioGRID PMID: 24412244 |
|
|
430 |
Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western |
|
|
431 |
BioGRID:112670 BioGRID:109552 HSP90AA1 BioGRID PMID: 33961781,32707033,28514442,22939624,21860411,14676191,14668798 |
|
|
432 |
Affinity Capture-MS |
|
|
433 |
BioGRID:112670 BioGRID:109555 HSP90AA4P BioGRID PMID: 33961781,28514442 |
|
|
434 |
Affinity Capture-MS |
|
|
435 |
BioGRID:112670 BioGRID:610599 HSP90AA5P BioGRID PMID: 33961781,28514442 |
|
|
436 |
Affinity Capture-MS |
|
|
437 |
BioGRID:112670 BioGRID:109558 HSP90AB1 BioGRID PMID: 33961781,32707033,28514442 |
|
|
438 |
Affinity Capture-MS |
|
|
439 |
BioGRID:112670 BioGRID:109559 HSP90AB3P BioGRID PMID: 33961781,28514442 |
|
|
440 |
Affinity Capture-MS |
|
|
441 |
BioGRID:112670 BioGRID:576430 HSP90AB4P BioGRID PMID: 33961781,28514442 |
|
|
442 |
Affinity Capture-MS |
|
|
443 |
BioGRID:112670 BioGRID:109535 HSPA1A BioGRID PMID: 14676191 |
|
|
444 |
Affinity Capture-MS |
|
|
445 |
BioGRID:112670 BioGRID:118149 HTATSF1 BioGRID PMID: 33961781 |
|
|
446 |
Affinity Capture-MS |
|
|
447 |
BioGRID:112670 BioGRID:120824 IARS2 BioGRID PMID: 34591612 |
|
|
448 |
Two-hybrid |
|
|
449 |
BioGRID:112670 BioGRID:109707 IGFBP3 BioGRID PMID: 24412244 |
|
|
450 |
Affinity Capture-MS |
|
|
451 |
BioGRID:112670 BioGRID:109714 IGHA1 BioGRID PMID: 33961781 |
|
|
452 |
Affinity Capture-MS |
|
|
453 |
BioGRID:112670 BioGRID:109715 IGHA2 BioGRID PMID: 33961781 |
|
|
454 |
Negative Genetic |
|
|
455 |
BioGRID:112670 BioGRID:114089 IKBKG BioGRID PMID: 35559673 |
|
|
456 |
Affinity Capture-MS |
|
|
457 |
BioGRID:112670 BioGRID:109772 IL1RN BioGRID PMID: 33961781 |
|
|
458 |
Affinity Capture-MS |
|
|
459 |
BioGRID:112670 BioGRID:129701 INO80E BioGRID PMID: 33961781 |
|
|
460 |
Affinity Capture-MS |
|
|
461 |
BioGRID:112670 BioGRID:109916 IVD BioGRID PMID: 34591612,28514442 |
|
|
462 |
Affinity Capture-MS |
|
|
463 |
BioGRID:112670 BioGRID:109917 IVL BioGRID PMID: 33961781 |
|
|
464 |
Affinity Capture-MS |
|
|
465 |
BioGRID:112670 BioGRID:109732 JCHAIN BioGRID PMID: 33961781 |
|
|
466 |
Negative Genetic |
|
|
467 |
BioGRID:112670 BioGRID:116105 JTB BioGRID PMID: 35559673 |
|
|
468 |
FRET |
|
|
469 |
BioGRID:112670 BioGRID:108918 KAT2A BioGRID PMID: 28205554 |
|
|
470 |
FRET |
|
|
471 |
BioGRID:112670 BioGRID:116204 KDELR2 BioGRID PMID: 28205554 |
|
|
472 |
Affinity Capture-MS |
|
|
473 |
BioGRID:112670 BioGRID:115035 KDM4A BioGRID PMID: 33961781,28514442 |
|
|
474 |
Affinity Capture-MS |
|
|
475 |
BioGRID:112670 BioGRID:114873 KIF23 BioGRID PMID: 14676191 |
|
|
476 |
Affinity Capture-MS |
|
|
477 |
BioGRID:112670 BioGRID:111636 KLK10 BioGRID PMID: 33961781 |
|
|
478 |
Two-hybrid |
|
|
479 |
BioGRID:112670 BioGRID:111631 KLK7 BioGRID PMID: 25640309 |
|
|
480 |
Negative Genetic |
|
|
481 |
BioGRID:112670 BioGRID:110038 KPNA4 BioGRID PMID: 35559673 |
|
|
482 |
Affinity Capture-Western |
|
|
483 |
BioGRID:112670 BioGRID:120336 LAMTOR1 BioGRID PMID: 34821530 |
|
|
484 |
FRET |
|
|
485 |
BioGRID:112670 BioGRID:117727 LATS2 BioGRID PMID: 28205554 |
|
|
486 |
Two-hybrid |
|
|
487 |
BioGRID:112670 BioGRID:119354 LEF1 BioGRID PMID: 24412244 |
|
|
488 |
Affinity Capture-MS |
|
|
489 |
BioGRID:112670 BioGRID:110175 LIMS1 BioGRID PMID: 14676191 |
|
|
490 |
Affinity Capture-MS |
|
|
491 |
BioGRID:112670 BioGRID:110201 LOXL2 BioGRID PMID: 34591612 |
|
|
492 |
Affinity Capture-MS |
|
|
493 |
BioGRID:112670 BioGRID:110208 LPP BioGRID PMID: 34591612 |
|
|
494 |
Affinity Capture-MS |
|
|
495 |
BioGRID:112670 BioGRID:110235 LTF BioGRID PMID: 33961781 |
|
|
496 |
Two-hybrid |
|
|
497 |
BioGRID:112670 BioGRID:117985 LYPD3 BioGRID PMID: 25640309 |
|
|
498 |
Affinity Capture-MS |
|
|
499 |
BioGRID:112670 BioGRID:110247 LYZ BioGRID PMID: 33961781 |
|
|
500 |
Negative Genetic |
|
|
501 |
BioGRID:112670 BioGRID:116348 LZTS1 BioGRID PMID: 35559673 |
|
|
502 |
Synthetic Lethality; Two-hybrid |
|
|
503 |
BioGRID:112670 BioGRID:111590 MAP2K1 BioGRID PMID: 27453043,24412244 |
|
|
504 |
Affinity Capture-Western; FRET |
|
|
505 |
BioGRID:112670 BioGRID:111592 MAP2K3 BioGRID PMID: 28628118,28205554 |
|
|
506 |
FRET |
|
|
507 |
BioGRID:112670 BioGRID:111593 MAP2K5 BioGRID PMID: 28205554 |
|
|
508 |
FRET |
|
|
509 |
BioGRID:112670 BioGRID:111594 MAP2K6 BioGRID PMID: 28205554 |
|
|
510 |
FRET |
|
|
511 |
BioGRID:112670 BioGRID:110381 MAP3K5 BioGRID PMID: 28205554 |
|
|
512 |
FRET |
|
|
513 |
BioGRID:112670 BioGRID:107819 MAPK14 BioGRID PMID: 28205554 |
|
|
514 |
Two-hybrid |
|
|
515 |
BioGRID:112670 BioGRID:111581 MAPK3 BioGRID PMID: 24412244 |
|
|
516 |
Two-hybrid |
|
|
517 |
BioGRID:112670 BioGRID:116581 MAPRE1 BioGRID PMID: 24552808 |
|
|
518 |
Biochemical Activity |
|
|
519 |
BioGRID:112670 BioGRID:108326 MARK2 BioGRID PMID: 16396636 |
|
|
520 |
Affinity Capture-Western |
|
|
521 |
BioGRID:112670 BioGRID:121760 MARK4 BioGRID PMID: 14676191 |
|
|
522 |
Negative Genetic |
|
|
523 |
BioGRID:112670 BioGRID:129033 MCM9 BioGRID PMID: 35559673 |
|
|
524 |
Affinity Capture-Western; FRET |
|
|
525 |
BioGRID:112670 BioGRID:110358 MDM2 BioGRID PMID: 35513074,28205554 |
|
|
526 |
FRET |
|
|
527 |
BioGRID:112670 BioGRID:110391 MET BioGRID PMID: 28205554 |
|
|
528 |
Affinity Capture-MS |
|
|
529 |
BioGRID:112670 BioGRID:119275 MLXIPL BioGRID PMID: 34461288 |
|
|
530 |
Affinity Capture-MS; Co-localization |
|
|
531 |
BioGRID:112670 BioGRID:122103 MMS19 BioGRID PMID: 34591612 |
|
|
532 |
Two-hybrid |
|
|
533 |
BioGRID:112670 BioGRID:110481 MOCS2 BioGRID PMID: 25640309 |
|
|
534 |
Affinity Capture-MS |
|
|
535 |
BioGRID:112670 BioGRID:110493 MPO BioGRID PMID: 33961781 |
|
|
536 |
Negative Genetic |
|
|
537 |
BioGRID:112670 BioGRID:110498 MPV17 BioGRID PMID: 35559673 |
|
|
538 |
Negative Genetic |
|
|
539 |
BioGRID:112670 BioGRID:125820 MTFMT BioGRID PMID: 35559673 |
|
|
540 |
Affinity Capture-MS |
|
|
541 |
BioGRID:112670 BioGRID:114560 MTMR4 BioGRID PMID: 33961781 |
|
|
542 |
Affinity Capture-MS |
|
|
543 |
BioGRID:112670 BioGRID:608337 MUC5B BioGRID PMID: 33961781 |
|
|
544 |
Affinity Capture-MS |
|
|
545 |
BioGRID:112670 BioGRID:110676 MUC7 BioGRID PMID: 33961781 |
|
|
546 |
FRET |
|
|
547 |
BioGRID:112670 BioGRID:110694 MYC BioGRID PMID: 28205554 |
|
|
548 |
Two-hybrid |
|
|
549 |
BioGRID:112670 BioGRID:119921 NANS BioGRID PMID: 24412244 |
|
|
550 |
Two-hybrid |
|
|
551 |
BioGRID:112670 BioGRID:106528 NAT2 BioGRID PMID: 25640309 |
|
|
552 |
Two-hybrid |
|
|
553 |
BioGRID:112670 BioGRID:110632 ND2 BioGRID PMID: 25640309 |
|
|
554 |
Negative Genetic |
|
|
555 |
BioGRID:112670 BioGRID:110792 NDUFB6 BioGRID PMID: 35559673 |
|
|
556 |
Affinity Capture-MS |
|
|
557 |
BioGRID:112670 BioGRID:114594 NEMF BioGRID PMID: 28514442 |
|
|
558 |
Affinity Capture-MS |
|
|
559 |
BioGRID:112670 BioGRID:115983 NES BioGRID PMID: 33961781 |
|
|
560 |
FRET |
|
|
561 |
BioGRID:112670 BioGRID:110844 NF2 BioGRID PMID: 28205554 |
|
|
562 |
Negative Genetic |
|
|
563 |
BioGRID:112670 BioGRID:117008 OTP BioGRID PMID: 35559673 |
|
|
564 |
Affinity Capture-MS |
|
|
565 |
BioGRID:112670 BioGRID:116413 PACSIN2 BioGRID PMID: 33961781 |
|
|
566 |
FRET |
|
|
567 |
BioGRID:112670 BioGRID:111182 PDGFRA BioGRID PMID: 28205554 |
|
|
568 |
Negative Genetic |
|
|
569 |
BioGRID:112670 BioGRID:116848 PDS5A BioGRID PMID: 35559673 |
|
|
570 |
Negative Genetic |
|
|
571 |
BioGRID:112670 BioGRID:117125 PDSS1 BioGRID PMID: 35559673 |
|
|
572 |
Two-hybrid |
|
|
573 |
BioGRID:112670 BioGRID:121330 PDXP BioGRID PMID: 25640309 |
|
|
574 |
Affinity Capture-MS |
|
|
575 |
BioGRID:112670 BioGRID:111788 PEX5 BioGRID PMID: 33961781 |
|
|
576 |
Two-hybrid |
|
|
577 |
BioGRID:112670 BioGRID:122561 PHF23 BioGRID PMID: 25640309 |
|
|
578 |
Affinity Capture-MS |
|
|
579 |
BioGRID:112670 BioGRID:111302 PIGR BioGRID PMID: 33961781 |
|
|
580 |
FRET |
|
|
581 |
BioGRID:112670 BioGRID:111308 PIK3CA BioGRID PMID: 28205554 |
|
|
582 |
Affinity Capture-MS |
|
|
583 |
BioGRID:112670 BioGRID:111322 PIP4K2A BioGRID PMID: 33961781,32707033,28514442 |
|
|
584 |
Affinity Capture-MS |
|
|
585 |
BioGRID:112670 BioGRID:113985 PIP4K2B BioGRID PMID: 32707033 |
|
|
586 |
Affinity Capture-MS |
|
|
587 |
BioGRID:112670 BioGRID:122928 PIP4K2C BioGRID PMID: 33961781 |
|
|
588 |
Affinity Capture-MS |
|
|
589 |
BioGRID:112670 BioGRID:114074 PKP4 BioGRID PMID: 34591612 |
|
|
590 |
Two-hybrid |
|
|
591 |
BioGRID:112670 BioGRID:117173 PLD3 BioGRID PMID: 25640309 |
|
|
592 |
Affinity Capture-MS |
|
|
593 |
BioGRID:112670 BioGRID:126828 PLEKHA7 BioGRID PMID: 34591612 |
|
|
594 |
Affinity Capture-MS |
|
|
595 |
BioGRID:112670 BioGRID:123048 POF1B BioGRID PMID: 33961781 |
|
|
596 |
Affinity Capture-MS |
|
|
597 |
BioGRID:112670 BioGRID:111488 PPL BioGRID PMID: 33961781 |
|
|
598 |
Two-hybrid |
|
|
599 |
BioGRID:112670 BioGRID:111508 PPP2CB BioGRID PMID: 24412244 |
|
|
600 |
Negative Genetic |
|
|
601 |
BioGRID:112670 BioGRID:120344 PPP2R3C BioGRID PMID: 35559673 |
|
|
602 |
Affinity Capture-Western; Biochemical Activity; Two-hybrid |
|
|
603 |
BioGRID:112670 BioGRID:111549 PRKAA1 BioGRID PMID: 31995728,31217475,16912160 |
|
|
604 |
Co-localization |
|
|
605 |
BioGRID:112670 BioGRID:111550 PRKAA2 BioGRID PMID: 25241761 |
|
|
606 |
Co-localization |
|
|
607 |
BioGRID:112670 BioGRID:111558 PRKAG1 BioGRID PMID: 31983282 |
|
|
608 |
Negative Genetic |
|
|
609 |
BioGRID:112670 BioGRID:114143 PRKRA BioGRID PMID: 35559673 |
|
|
610 |
Two-hybrid |
|
|
611 |
BioGRID:112670 BioGRID:118887 PRSS50 BioGRID PMID: 25640309 |
|
|
612 |
Affinity Capture-MS |
|
|
613 |
BioGRID:112670 BioGRID:111638 PRTN3 BioGRID PMID: 33961781 |
|
|
614 |
Negative Genetic |
|
|
615 |
BioGRID:112670 BioGRID:114872 PSMF1 BioGRID PMID: 35559673 |
|
|
616 |
Affinity Capture-Western; Biochemical Activity; Co-localization; Two-hybrid |
|
|
617 |
BioGRID:112670 BioGRID:111700 PTEN BioGRID PMID: 15987703 |
|
|
618 |
Two-hybrid |
|
|
619 |
BioGRID:112670 BioGRID:111856 RASA1 BioGRID PMID: 24412244 |
|
|
620 |
FRET |
|
|
621 |
BioGRID:112670 BioGRID:116356 RASSF1 BioGRID PMID: 28205554 |
|
|
622 |
Two-hybrid |
|
|
623 |
BioGRID:112670 BioGRID:116828 RHOBTB2 BioGRID PMID: 25640309 |
|
|
624 |
Affinity Capture-MS |
|
|
625 |
BioGRID:112670 BioGRID:121946 RIC8A BioGRID PMID: 34591612 |
|
|
626 |
Affinity Capture-RNA |
|
|
627 |
BioGRID:112670 BioGRID:117121 RIGI BioGRID PMID: 32513696 |
|
|
628 |
Affinity Capture-MS |
|
|
629 |
BioGRID:112670 BioGRID:120896 RIOK2 BioGRID PMID: 33961781 |
|
|
630 |
Affinity Capture-Western |
|
|
631 |
BioGRID:112670 BioGRID:123598 RNF146 BioGRID PMID: 31554794 |
|
|
632 |
Affinity Capture-MS |
|
|
633 |
BioGRID:112670 BioGRID:122783 RPAP3 BioGRID PMID: 14676191 |
|
|
634 |
Negative Genetic |
|
|
635 |
BioGRID:112670 BioGRID:121820 RPRD1B BioGRID PMID: 35559673 |
|
|
636 |
Co-localization |
|
|
637 |
BioGRID:112670 BioGRID:112112 RPS6KB1 BioGRID PMID: 25241761 |
|
|
638 |
Two-hybrid |
|
|
639 |
BioGRID:112670 BioGRID:121504 S100A14 BioGRID PMID: 25640309 |
|
|
640 |
Affinity Capture-MS |
|
|
641 |
BioGRID:112670 BioGRID:112188 S100A9 BioGRID PMID: 33961781 |
|
|
642 |
Affinity Capture-MS |
|
|
643 |
BioGRID:112670 BioGRID:114324 SCEL BioGRID PMID: 33961781 |
|
|
644 |
Negative Genetic |
|
|
645 |
BioGRID:112670 BioGRID:112291 SDHB BioGRID PMID: 35559673 |
|
|
646 |
Two-hybrid |
|
|
647 |
BioGRID:112670 BioGRID:116015 SEPTIN9 BioGRID PMID: 25640309 |
|
|
648 |
Affinity Capture-MS |
|
|
649 |
BioGRID:112670 BioGRID:108307 SERPINB1 BioGRID PMID: 33961781 |
|
|
650 |
Affinity Capture-MS |
|
|
651 |
BioGRID:112670 BioGRID:111293 SERPINB13 BioGRID PMID: 33961781 |
|
|
652 |
Affinity Capture-MS |
|
|
653 |
BioGRID:112670 BioGRID:112223 SERPINB3 BioGRID PMID: 33961781 |
|
|
654 |
Affinity Capture-MS |
|
|
655 |
BioGRID:112670 BioGRID:112224 SERPINB4 BioGRID PMID: 33961781 |
|
|
656 |
Affinity Capture-MS; Two-hybrid |
|
|
657 |
BioGRID:112670 BioGRID:111286 SERPINB5 BioGRID PMID: 33961781,25640309 |
|
|
658 |
Affinity Capture-MS |
|
|
659 |
BioGRID:112670 BioGRID:118845 SETD2 BioGRID PMID: 33961781 |
|
|
660 |
Biochemical Activity |
|
|
661 |
BioGRID:112670 BioGRID:127260 SIK1 BioGRID PMID: 16396636 |
|
|
662 |
Affinity Capture-Western; Biochemical Activity |
|
|
663 |
BioGRID:112670 BioGRID:116983 SIRT1 BioGRID PMID: 27259994,18687677 |
|
|
664 |
Negative Genetic |
|
|
665 |
BioGRID:112670 BioGRID:124002 SLC25A33 BioGRID PMID: 35559673 |
|
|
666 |
Negative Genetic |
|
|
667 |
BioGRID:112670 BioGRID:115726 SLC30A9 BioGRID PMID: 35559673 |
|
|
668 |
FRET |
|
|
669 |
BioGRID:112670 BioGRID:110261 SMAD1 BioGRID PMID: 28205554 |
|
|
670 |
Affinity Capture-MS; Affinity Capture-Western; FRET; Reconstituted Complex |
|
|
671 |
BioGRID:112670 BioGRID:112481 SMARCA4 BioGRID PMID: 28205554,14676191,11445556 |
|
|
672 |
Affinity Capture-MS |
|
|
673 |
BioGRID:112670 BioGRID:112483 SMARCC1 BioGRID PMID: 14676191 |
|
|
674 |
Affinity Capture-Western |
|
|
675 |
BioGRID:112670 BioGRID:112499 SNAI1 BioGRID PMID: 29601127 |
|
|
676 |
Biochemical Activity |
|
|
677 |
BioGRID:112670 BioGRID:120211 SNRK BioGRID PMID: 15733851 |
|
|
678 |
Affinity Capture-MS |
|
|
679 |
BioGRID:112670 BioGRID:119535 SNX9 BioGRID PMID: 33961781 |
|
|
680 |
Negative Genetic |
|
|
681 |
BioGRID:112670 BioGRID:119936 SOX18 BioGRID PMID: 35559673 |
|
|
682 |
FRET |
|
|
683 |
BioGRID:112670 BioGRID:112542 SOX4 BioGRID PMID: 28205554 |
|
|
684 |
Two-hybrid |
|
|
685 |
BioGRID:112670 BioGRID:117335 SPDEF BioGRID PMID: 16912160 |
|
|
686 |
Affinity Capture-MS |
|
|
687 |
BioGRID:112670 BioGRID:112585 SPRR3 BioGRID PMID: 33961781 |
|
|
688 |
Two-hybrid |
|
|
689 |
BioGRID:112670 BioGRID:112645 ST14 BioGRID PMID: 25640309 |
|
|
690 |
FRET |
|
|
691 |
BioGRID:112670 BioGRID:112670 STK11 BioGRID PMID: 28205554 |
|
|
692 |
Affinity Capture-Western |
|
|
693 |
BioGRID:112670 BioGRID:125352 STK11IP BioGRID PMID: 11741830 |
|
|
694 |
Two-hybrid |
|
|
695 |
BioGRID:112670 BioGRID:114011 STK24 BioGRID PMID: 25640309 |
|
|
696 |
Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Co-localization; Reconstituted Complex; Two-hybrid |
|
|
697 |
BioGRID:112670 BioGRID:124934 STRADA BioGRID PMID: 35271311,34591612,33961781,32707033,31554794,28514442,25852190,25241761,21860411,20562859,15561763,14676191,12805220 |
|
|
698 |
Affinity Capture-MS; Biochemical Activity |
|
|
699 |
BioGRID:112670 BioGRID:120668 STRADB BioGRID PMID: 35271311,34591612,33961781,32707033,28514442,20562859,14676191 |
|
|
700 |
Affinity Capture-Western |
|
|
701 |
BioGRID:112670 BioGRID:115563 STUB1 BioGRID PMID: 21860411 |
|
|
702 |
Two-hybrid |
|
|
703 |
BioGRID:112670 BioGRID:120346 STX17 BioGRID PMID: 24412244 |
|
|
704 |
Affinity Capture-MS |
|
|
705 |
BioGRID:112670 BioGRID:112689 SULT2B1 BioGRID PMID: 33961781 |
|
|
706 |
Affinity Capture-MS |
|
|
707 |
BioGRID:112670 BioGRID:112697 SUPT5H BioGRID PMID: 33961781 |
|
|
708 |
Affinity Capture-MS |
|
|
709 |
BioGRID:112670 BioGRID:112698 SUPT6H BioGRID PMID: 33961781 |
|
|
710 |
Two-hybrid |
|
|
711 |
BioGRID:112670 BioGRID:120889 TBC1D23 BioGRID PMID: 21516116 |
|
|
712 |
Two-hybrid |
|
|
713 |
BioGRID:112670 BioGRID:116994 TDRD7 BioGRID PMID: 24412244 |
|
|
714 |
FRET |
|
|
715 |
BioGRID:112670 BioGRID:114041 TEAD2 BioGRID PMID: 28205554 |
|
|
716 |
FRET |
|
|
717 |
BioGRID:112670 BioGRID:112874 TERT BioGRID PMID: 28205554 |
|
|
718 |
Affinity Capture-MS |
|
|
719 |
BioGRID:112670 BioGRID:112909 TGM1 BioGRID PMID: 33961781 |
|
|
720 |
Affinity Capture-MS |
|
|
721 |
BioGRID:112670 BioGRID:112911 TGM3 BioGRID PMID: 33961781 |
|
|
722 |
Two-hybrid |
|
|
723 |
BioGRID:112670 BioGRID:112921 THOP1 BioGRID PMID: 25640309 |
|
|
724 |
Two-hybrid |
|
|
725 |
BioGRID:112670 BioGRID:112925 THRSP BioGRID PMID: 25640309 |
|
|
726 |
FRET |
|
|
727 |
BioGRID:112670 BioGRID:112986 TNFRSF1A BioGRID PMID: 28205554 |
|
|
728 |
Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
|
|
729 |
BioGRID:112670 BioGRID:122573 TNIP2 BioGRID PMID: 27609421,12753905,12595760 |
|
|
730 |
Affinity Capture-Western |
|
|
731 |
BioGRID:112670 BioGRID:114207 TNKS BioGRID PMID: 31554794 |
|
|
732 |
Affinity Capture-Western |
|
|
733 |
BioGRID:112670 BioGRID:123257 TNKS2 BioGRID PMID: 31554794 |
|
|
734 |
Affinity Capture-MS; Affinity Capture-Western; FRET |
|
|
735 |
BioGRID:112670 BioGRID:113010 TP53 BioGRID PMID: 33961781,28205554,11430832 |
|
|
736 |
Affinity Capture-Western |
|
|
737 |
BioGRID:112670 BioGRID:114181 TP63 BioGRID PMID: 21150337 |
|
|
738 |
Two-hybrid |
|
|
739 |
BioGRID:112670 BioGRID:113500 TRIM25 BioGRID PMID: 25640309 |
|
|
740 |
Two-hybrid |
|
|
741 |
BioGRID:112670 BioGRID:119593 TRMO BioGRID PMID: 24412244 |
|
|
742 |
Negative Genetic |
|
|
743 |
BioGRID:112670 BioGRID:113100 TSC2 BioGRID PMID: 35559673 |
|
|
744 |
Two-hybrid |
|
|
745 |
BioGRID:112670 BioGRID:113102 TSG101 BioGRID PMID: 25640309 |
|
|
746 |
Two-hybrid |
|
|
747 |
BioGRID:112670 BioGRID:113603 TUBA1A BioGRID PMID: 25640309 |
|
|
748 |
Two-hybrid |
|
|
749 |
BioGRID:112670 BioGRID:115655 TUBB4A BioGRID PMID: 25640309 |
|
|
750 |
Negative Genetic |
|
|
751 |
BioGRID:112670 BioGRID:113149 TYMS BioGRID PMID: 35559673 |
|
|
752 |
Biochemical Activity |
|
|
753 |
BioGRID:112670 BioGRID:113170 UBE2D2 BioGRID PMID: 21860411 |
|
|
754 |
Affinity Capture-Western |
|
|
755 |
BioGRID:112670 BioGRID:121973 UBE2O BioGRID PMID: 31900314 |
|
|
756 |
Negative Genetic |
|
|
757 |
BioGRID:112670 BioGRID:118858 UBE2T BioGRID PMID: 35559673 |
|
|
758 |
Affinity Capture-MS |
|
|
759 |
BioGRID:112670 BioGRID:113866 USP11 BioGRID PMID: 14676191 |
|
|
760 |
Two-hybrid |
|
|
761 |
BioGRID:112670 BioGRID:112804 VPS72 BioGRID PMID: 25640309 |
|
|
762 |
Affinity Capture-MS |
|
|
763 |
BioGRID:112670 BioGRID:121649 WDR48 BioGRID PMID: 19615732 |
|
|
764 |
Affinity Capture-Western |
|
|
765 |
BioGRID:112670 BioGRID:116350 WDR6 BioGRID PMID: 17216128 |
|
|
766 |
FRET |
|
|
767 |
BioGRID:112670 BioGRID:113327 WT1 BioGRID PMID: 28205554 |
|
|
768 |
Two-hybrid |
|
|
769 |
BioGRID:112670 BioGRID:113344 XPA BioGRID PMID: 24412244 |
|
|
770 |
Negative Genetic |
|
|
771 |
BioGRID:112670 BioGRID:119655 YPEL5 BioGRID PMID: 35559673 |
|
|
772 |
FRET |
|
|
773 |
BioGRID:112670 BioGRID:113364 YWHAG BioGRID PMID: 28205554 |
|
|
774 |
Affinity Capture-MS |
|
|
775 |
BioGRID:112670 BioGRID:125855 ZG16B BioGRID PMID: 33961781 |
|
|
776 |
Two-hybrid |
|
|
777 |
BioGRID:112670 BioGRID:113528 ZNF189 BioGRID PMID: 24412244 |
|
|
778 |
Two-hybrid |
|
|
779 |
BioGRID:112670 BioGRID:116536 ZNF510 BioGRID PMID: 24412244 |
|
|
780 |
|
|
|
781 |
GENERAL GENE INFO |
|
|
782 |
------------------------------------------------------------------------------------------------- |
|
|
783 |
|
|
|
784 |
Marker |
|
|
785 |
REU1905 (e-PCR) Links:UniSTS:257089 |
|
|
786 |
RH104368 (e-PCR) Links:UniSTS:98693 |
|
|
787 |
Stk11 (e-PCR), detects polymorphism Links:UniSTS:546518 |
|
|
788 |
|
|
|
789 |
|
|
|
790 |
Homology |
|
|
791 |
Homologs of the STK11 gene |
|
|
792 |
The STK11 gene is conserved in chimpanzee, Rhesus monkey, dog, mouse, rat, chicken, zebrafish, mosquito, C.elegans, and frog. |
|
|
793 |
Orthologs from Annotation Pipeline (/gene/?Term=ortholog_gene_6794[group]): |
|
|
794 |
Orthologs |
|
|
795 |
|
|
|
796 |
Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA) |
|
|
797 |
|
|
|
798 |
Function GO ID Evidence |
|
|
799 |
------------------------------------------------------------------------------------------------- |
|
|
800 |
enables ATP binding GO:0000000 PMID: 12805220 |
|
|
801 |
enables LRR domain binding GO:0000000 - |
|
|
802 |
enables magnesium ion binding GO:0000000 PMID: 12805220 |
|
|
803 |
enables p53 binding GO:0000000 PMID: 11430832 |
|
|
804 |
enables protein binding GO:0000000 PMID: 12595760,12753905,12805220,14676191,17216128,19274086,19513107,19892943,20562859,22575644,22939624,24362629,25036637,25241761,25329316,25852190,26479318,28514442,32707033,34591612 |
|
|
805 |
enables protein kinase activator activit... GO:0000000 PMID: 19892943 |
|
|
806 |
enables protein serine kinase activity GO:0000000 - |
|
|
807 |
enables protein serine/threonine kinase ... GO:0000000 PMID: 21873635 |
|
|
808 |
enables protein serine/threonine kinase ... GO:0000000 PMID: 11430832,12805220,19892943 |
|
|
809 |
enables protein serine/threonine kinase ... GO:0000000 - |
|
|
810 |
enables protein-containing complex bindi... GO:0000000 - |
|
|
811 |
|
|
|
812 |
Processs GO ID Evidence |
|
|
813 |
------------------------------------------------------------------------------------------------- |
|
|
814 |
involved_in DNA damage response GO:0000000 PMID: 21873635 |
|
|
815 |
involved_in DNA damage response GO:0000000 PMID: 25329316 |
|
|
816 |
acts_upstream_of_negative_effect G1 to G... GO:0000000 PMID: 17216128 |
|
|
817 |
acts_upstream_of_negative_effect G1 to G... GO:0000000 PMID: 12805220 |
|
|
818 |
involved_in Golgi localization GO:0000000 - |
|
|
819 |
involved_in T cell receptor signaling pa... GO:0000000 - |
|
|
820 |
involved_in activation of protein kinase... GO:0000000 PMID: 19892943 |
|
|
821 |
involved_in activation of protein kinase... GO:0000000 PMID: 15731909 |
|
|
822 |
involved_in activation of protein kinase... GO:0000000 - |
|
|
823 |
involved_in anoikis GO:0000000 PMID: 19622832 |
|
|
824 |
involved_in autophagy GO:0000000 - |
|
|
825 |
involved_in axonogenesis GO:0000000 - |
|
|
826 |
involved_in cellular response to UV-B GO:0000000 PMID: 25329316 |
|
|
827 |
involved_in dendrite extension GO:0000000 - |
|
|
828 |
involved_in epithelial cell proliferatio... GO:0000000 - |
|
|
829 |
involved_in establishment of cell polari... GO:0000000 PMID: 21873635 |
|
|
830 |
involved_in establishment of cell polari... GO:0000000 PMID: 24643070 |
|
|
831 |
involved_in establishment of cell polari... GO:0000000 - |
|
|
832 |
involved_in glucose homeostasis GO:0000000 - |
|
|
833 |
involved_in intrinsic apoptotic signalin... GO:0000000 PMID: 11430832 |
|
|
834 |
involved_in negative regulation of TORC1... GO:0000000 PMID: 23878245 |
|
|
835 |
involved_in negative regulation of canon... GO:0000000 PMID: 15731909 |
|
|
836 |
involved_in negative regulation of cell ... GO:0000000 - |
|
|
837 |
involved_in negative regulation of cell ... GO:0000000 PMID: 17216128,25329316 |
|
|
838 |
involved_in negative regulation of cold-... GO:0000000 PMID: 27461402 |
|
|
839 |
involved_in negative regulation of epith... GO:0000000 - |
|
|
840 |
involved_in peptidyl-threonine phosphory... GO:0000000 PMID: 12805220 |
|
|
841 |
involved_in positive regulation of autop... GO:0000000 PMID: 23878245 |
|
|
842 |
involved_in positive regulation of axono... GO:0000000 - |
|
|
843 |
involved_in positive regulation of gluco... GO:0000000 - |
|
|
844 |
involved_in positive regulation of prote... GO:0000000 - |
|
|
845 |
involved_in positive regulation of trans... GO:0000000 PMID: 18311138 |
|
|
846 |
involved_in positive regulation of vesic... GO:0000000 PMID: 21873635 |
|
|
847 |
involved_in positive regulation of vesic... GO:0000000 PMID: 24643070 |
|
|
848 |
involved_in positive thymic T cell selec... GO:0000000 - |
|
|
849 |
involved_in protein autophosphorylation GO:0000000 PMID: 11430832 |
|
|
850 |
involved_in protein dephosphorylation GO:0000000 PMID: 15731909 |
|
|
851 |
involved_in protein localization to nucl... GO:0000000 - |
|
|
852 |
involved_in protein phosphorylation GO:0000000 PMID: 21873635 |
|
|
853 |
involved_in protein phosphorylation GO:0000000 PMID: 12805220,25329316 |
|
|
854 |
involved_in regulation of Wnt signaling ... GO:0000000 PMID: 21873635 |
|
|
855 |
involved_in regulation of cell cycle GO:0000000 - |
|
|
856 |
involved_in regulation of cell growth GO:0000000 - |
|
|
857 |
involved_in regulation of dendrite morph... GO:0000000 - |
|
|
858 |
involved_in regulation of protein kinase... GO:0000000 - |
|
|
859 |
involved_in regulation of signal transdu... GO:0000000 - |
|
|
860 |
involved_in response to activity GO:0000000 - |
|
|
861 |
involved_in response to glucagon GO:0000000 - |
|
|
862 |
involved_in response to ionizing radiati... GO:0000000 - |
|
|
863 |
involved_in response to lipid GO:0000000 - |
|
|
864 |
involved_in response to thyroid hormone GO:0000000 - |
|
|
865 |
involved_in signal transduction GO:0000000 PMID: 21873635 |
|
|
866 |
involved_in spermatogenesis GO:0000000 - |
|
|
867 |
involved_in tissue homeostasis GO:0000000 - |
|
|
868 |
involved_in vasculature development GO:0000000 - |
|
|
869 |
|
|
|
870 |
Component GO ID Evidence |
|
|
871 |
------------------------------------------------------------------------------------------------- |
|
|
872 |
located_in Z disc GO:0000000 - |
|
|
873 |
is_active_in cytoplasm GO:0000000 PMID: 21873635 |
|
|
874 |
located_in cytoplasm GO:0000000 PMID: 11430832,12805220,14517248,17216128,18854309 |
|
|
875 |
located_in cytoplasm GO:0000000 - |
|
|
876 |
located_in cytosol GO:0000000 - |
|
|
877 |
located_in cytosol GO:0000000 - |
|
|
878 |
located_in cytosol GO:0000000 - |
|
|
879 |
located_in extracellular exosome GO:0000000 PMID: 19056867 |
|
|
880 |
part_of intracellular protein-containing... GO:0000000 PMID: 12805220 |
|
|
881 |
located_in membrane GO:0000000 - |
|
|
882 |
located_in mitochondrion GO:0000000 PMID: 11430832 |
|
|
883 |
located_in nucleoplasm GO:0000000 - |
|
|
884 |
located_in nucleoplasm GO:0000000 - |
|
|
885 |
is_active_in nucleus GO:0000000 PMID: 21873635 |
|
|
886 |
located_in nucleus GO:0000000 PMID: 12805220,18854309 |
|
|
887 |
part_of serine/threonine protein kinase ... GO:0000000 PMID: 19892943 |
|
|
888 |
part_of serine/threonine protein kinase ... GO:0000000 - |
|
|
889 |
|
|
|
890 |
GENERAL PROTEIN INFORMATION |
|
|
891 |
------------------------------------------------------------------------------------------------- |
|
|
892 |
Preferred Names |
|
|
893 |
serine/threonine-protein kinase STK11 |
|
|
894 |
Names |
|
|
895 |
liver kinase B1 |
|
|
896 |
polarization-related protein LKB1 |
|
|
897 |
renal carcinoma antigen NY-REN-19 |
|
|
898 |
serine/threonine-protein kinase 11 |
|
|
899 |
serine/threonine-protein kinase LKB1 |
|
|
900 |
NP_000446.1 |
|
|
901 |
EC 2.7.11.1 |
|
|
902 |
NP_001394184.1 |
|
|
903 |
EC 2.7.11.1 |
|
|
904 |
|
|
|
905 |
NCBI REFERENCE SEQUENCES (RefSeq) |
|
|
906 |
------------------------------------------------------------------------------------------------- |
|
|
907 |
|
|
|
908 |
RefSeqs maintained independently of Annotated Genomes |
|
|
909 |
|
|
|
910 |
These reference sequences exist independently of genome builds. |
|
|
911 |
These reference sequences are curated independently of the genome annotation cycle, |
|
|
912 |
so their versions may not match the RefSeq versions in the current genome build. |
|
|
913 |
Identify version mismatches by comparing the version of the RefSeq in this section to |
|
|
914 |
the one reported in Genomic regions, transcripts, and products section above. |
|
|
915 |
|
|
|
916 |
Genomic |
|
|
917 |
NG_007460.2 RefSeqGene |
|
|
918 |
Range 21392..44028 |
|
|
919 |
Download GenBank FASTA Sequence Viewer (Graphics) |
|
|
920 |
|
|
|
921 |
|
|
|
922 |
|
|
|
923 |
mRNA and Protein(s) |
|
|
924 |
|
|
|
925 |
NM_000455.5 → NP_000446.1 REVIEWEDserine/threonine-protein kinase STK11 isoform 1 |
|
|
926 |
|
|
|
927 |
See proteins identical to NP_000446.1 at http://130.14.22.58/ipg/NP_000446.1/ |
|
|
928 |
|
|
|
929 |
Source sequence(s): AC011544, BC007981, BC019334, BM993274, BQ222023, BU174122, BU739451 |
|
|
930 |
Consensus CDS: CCDS45896.1 |
|
|
931 |
UniProtKB/TrEMBL: A0A0S2Z4D1 |
|
|
932 |
UniProtKB/Swiss-Prot: E7EW76 |
|
|
933 |
UniProtKB/Swiss-Prot: Q15831 |
|
|
934 |
|
|
|
935 |
Related Ensembl: ENSP00000324856.6, ENST00000326873.12 |
|
|
936 |
Conserved Domains (1)summary |
|
|
937 |
cd14119: |
|
|
938 |
Location:55 - 309 |
|
|
939 |
STKc_LKB1; Catalytic domain of the Serine/Threonine kinase, Liver Kinase B1 |
|
|
940 |
|
|
|
941 |
NM_001407255.1 → NP_001394184.1 REVIEWEDserine/threonine-protein kinase STK11 isoform 2 |
|
|
942 |
Source sequence(s): AC011544 |
|
|
943 |
|
|
|
944 |
RNA |
|
|
945 |
|
|
|
946 |
NR_176325.1 RNA Sequence |
|
|
947 |
Source sequence(s): AC004221, AC011544 |
|
|
948 |
|
|
|
949 |
RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_03 |
|
|
950 |
The following sections contain reference sequences that belong to a specific genome build. |
|
|
951 |
This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which |
|
|
952 |
this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both |
|
|
953 |
reference and alternate assemblies. Model RNAs and proteins are also reported here. |
|
|
954 |
|
|
|
955 |
Reference GRCh38.p14 Primary Assembly |
|
|
956 |
|
|
|
957 |
Genomic |
|
|
958 |
NC_000019.10 Reference GRCh38.p14 Primary Assembly |
|
|
959 |
Range 1205777..1228430 |
|
|
960 |
Download GenBank FASTA Sequence Viewer (Graphics) |
|
|
961 |
|
|
|
962 |
Alternate T2T-CHM13v2.0 |
|
|
963 |
|
|
|
964 |
Genomic |
|
|
965 |
NC_060943.1 Alternate T2T-CHM13v2.0 |
|
|
966 |
Range 1174324..1196988 |
|
|
967 |
Download GenBank FASTA Sequence Viewer (Graphics) |
|
|
968 |
|
|
|
969 |
|
|
|
970 |
|
|
|
971 |
RELATED SEQUENCES |
|
|
972 |
------------------------------------------------------------------------------------------------- |
|
|
973 |
|
|
|
974 |
Nucleotide Protein |
|
|
975 |
------------------------------------------------------------------------------------------------- |
|
|
976 |
genomic AC004221.2 AAF97257.1 |
|
|
977 |
genomic AC011544.6(26171..45903) None |
|
|
978 |
genomic AH005839.2 AAB97833.1 |
|
|
979 |
genomic AH006100.2 AAC15742.1 |
|
|
980 |
genomic CH471139.2 EAW69538.1 |
|
|
981 |
EAW69539 |
|
|
982 |
EAW69540 |
|
|
983 |
genomic CP068259.2(1174325..1196989) None |
|
|
984 |
mRNA AB209553.1 BAD92790.1 |
|
|
985 |
mRNA AF035625.1 AAC39527.1 |
|
|
986 |
mRNA AF217978.1 AAG17221.1 |
|
|
987 |
mRNA AJ844634.2 CAH59749.2 |
|
|
988 |
mRNA AK128518.1 None |
|
|
989 |
mRNA AK314858.1 BAG37374.1 |
|
|
990 |
mRNA BC007981.2 AAH07981.1 |
|
|
991 |
mRNA BC019334.1 AAH19334.1 |
|
|
992 |
mRNA BM993274.1 None |
|
|
993 |
mRNA BQ222023.1 None |
|
|
994 |
mRNA BU174122.1 None |
|
|
995 |
mRNA BU739451.1 None |
|
|
996 |
mRNA EF644172.1 ABR45718.1 |
|
|
997 |
mRNA GU573916.1 ADD71158.1 |
|
|
998 |
mRNA KU178339.1 ALQ33797.1 |
|
|
999 |
mRNA KU178340.1 ALQ33798.1 |
|
|
1000 |
mRNA U63333.1 AAB05809.1 |
|
|
1001 |
|
|
|
1002 |
Protein Accession Links |
|
|
1003 |
------------------------------------------------------------------------------------------------- |
|
|
1004 |
Q15831.1 GenPept(/protein/3024670) UniProtKB/Swiss-Prot:Q15831 |
|
|
1005 |
|
|
|
1006 |
GENE LINKOUT |
|
|
1007 |
------------------------------------------------------------------------------------------------- |
|
|
1008 |
The following LinkOut(www.ncbi.nlm.nih.gov/projects/linkout/index.html) resources |
|
|
1009 |
are supplied by external providers. These providers are responsible for |
|
|
1010 |
maintaining the links. |
|
|
1011 |
|
|
|
1012 |
Chemical Information |
|
|
1013 |
(Free resource) (free) Interologous Interaction Database |
|
|
1014 |
Interologous Interaction Database |
|
|
1015 |
(Order form) MilliporeSigma |
|
|
1016 |
Stk11 productsStk11 products |
|
|
1017 |
(Order form) Novus Biologicals |
|
|
1018 |
Peptides and ProteinsPeptides and ProteinsLysatesLysatesPrimary AntibodiesPrimary Antibodies |
|
|
1019 |
|
|
|
1020 |
Medical |
|
|
1021 |
(Free resource) (free) MedlinePlus Health Information |
|
|
1022 |
STK11 geneSTK11 gene |
|
|
1023 |
|
|
|
1024 |
Molecular Biology Databases |
|
|
1025 |
(Free resource) (free) Bgee database |
|
|
1026 |
STK11 gene expressionSTK11 gene expression |
|
|
1027 |
(Free resource) (free) BioGPS |
|
|
1028 |
BioGPS |
|
|
1029 |
(Free resource) (free) BioGRID Open Repository of CRISPR Screens (ORCS) |
|
|
1030 |
BioGRID CRISPR Screen Phenotypes (153 hits/1229 screens)BioGRID CRISPR Screen Phenotypes (153 hits/1229 screens) |
|
|
1031 |
(Free resource) (free) CREB Target Gene Database |
|
|
1032 |
CREB Target Gene Database |
|
|
1033 |
(Free resource) (Free registration required) (free) Creative Biogene |
|
|
1034 |
serine/threonine kinase 11serine/threonine kinase 11 |
|
|
1035 |
(Free resource) (free) Eukaryotic Promoter Database |
|
|
1036 |
STK11_1STK11_1 |
|
|
1037 |
(Free resource) (free) GenAge Database of Aging Related Genes |
|
|
1038 |
GenAge Database of Aging Related Genes |
|
|
1039 |
(Order form) GenScript latest version of gene cDNA ORF Clone |
|
|
1040 |
GenScript latest version of gene cDNA ORF Clone |
|
|
1041 |
(Free resource) (free) GeneNetwork |
|
|
1042 |
Records for gene expression in HumanRecords for gene expression in Human |
|
|
1043 |
(Free resource) (free) Genevisible |
|
|
1044 |
STK11STK11 |
|
|
1045 |
(Free resource) (free) GlyGen glycoinformatics resource |
|
|
1046 |
GlyGen glycoinformatics resource |
|
|
1047 |
(Free resource) (free) Guide to Pharmacology |
|
|
1048 |
serine/threonine kinase 11 geneserine/threonine kinase 11 gene |
|
|
1049 |
(Free resource) (Free registration required) (free) Human Gene Mutation Database |
|
|
1050 |
Human Gene Mutation Database |
|
|
1051 |
(Free resource) (free) Human eFP Browser |
|
|
1052 |
Human eFP BrowserHuman eFP BrowserHuman eFP Browser |
|
|
1053 |
Ingenuity Pathways Analysis |
|
|
1054 |
Ingenuity Pathways Analysis |
|
|
1055 |
(Free resource) (free) InnateDB |
|
|
1056 |
InnateDB |
|
|
1057 |
(Free resource) (free) InterMine |
|
|
1058 |
InterMine |
|
|
1059 |
(Free resource) (free) Kyoto Encyclopedia of Genes and Genomes |
|
|
1060 |
Kyoto Encyclopedia of Genes and Genomes |
|
|
1061 |
(Free resource) (free) Monarch Initiative |
|
|
1062 |
Monarch InitiativeMonarch Initiative |
|
|
1063 |
(Free resource) (free) OMA Browser: Orthologous MAtrix |
|
|
1064 |
OMA Browser: Orthologous MAtrixOMA Browser: Orthologous MAtrix |
|
|
1065 |
(Free resource) (free) OrthoDB catalog of orthologs |
|
|
1066 |
OrthologsOrthologs |
|
|
1067 |
(Free resource) (free) Pharmacogenomics Knowledge Base |
|
|
1068 |
Annotated Pharmacogenomic Information for STK11 [PharmGKB]Annotated Pharmacogenomic Information for STK11 [PharmGKB] |
|
|
1069 |
(Free resource) (free) PhosphoSitePlus |
|
|
1070 |
PhosphoSitePlus® - comprehensive post-translational modification resourcePhosphoSitePlus® - comprehensive post-translational modification resource |
|
|
1071 |
(Free resource) (free) Protein Ontology Consortium |
|
|
1072 |
Protein Ontology Consortium |
|
|
1073 |
(Free resource) (free) The Gene Wiki |
|
|
1074 |
The Gene Wiki |
|
|
1075 |
(Free resource) (free) The Weizmann Institute of Science GeneCards and MalaCards databases |
|
|
1076 |
GeneCard for STK11GeneCard for STK11 |
|
|
1077 |
(Free resource) (free) Vertebrate Genome Annotation (VEGA) database |
|
|
1078 |
Vertebrate Genome Annotation (VEGA) database |
|
|
1079 |
(Free resource) (free) iRefWeb - iRefIndex release 9.0 - Consolidated Interactome |
|
|
1080 |
iRefWeb - iRefIndex release 9.0 - Consolidated Interactome |
|
|
1081 |
|
|
|
1082 |
Research Materials |
|
|
1083 |
(Order form) Addgene Non-profit plasmid repository |
|
|
1084 |
Get Plasmids - AddgeneGet Plasmids - Addgene |
|
|
1085 |
ExactAntigen/Labome |
|
|
1086 |
reagent reviewreagent reviewreagentsreagents |
|
|
1087 |
(Order form) GeneCopoeia Inc. |
|
|
1088 |
Order miRNA target clonesOrder miRNA target clonesOrder shRNA clonesOrder shRNA clonesOrder full-length ORF cloneOrder full-length ORF clone |
|
|
1089 |
(Order form) GeneTex Inc |
|
|
1090 |
Find Recombinant Proteins and PeptidesFind Recombinant Proteins and PeptidesFind Quality AntibodiesFind Quality Antibodies |
|
|
1091 |
(Order form) Kazusa DNA Research Institute |
|
|
1092 |
Kazusa DNA Research Institute |
|
|
1093 |
LifeSpan BioSciences, Inc. |
|
|
1094 |
LSBio STK11 / LKB1 ProteinsLSBio STK11 / LKB1 Proteins |
|
|
1095 |
(Order form) NITE Biological Resource Center |
|
|
1096 |
Human cDNA clones used in NEDO Project / AK314858Human cDNA clones used in NEDO Project / AK314858Human cDNA clones used in NEDO Project / AK128518Human cDNA clones used in NEDO Project / AK128518 |
|
|
1097 |
(Order form) Sino Biological Inc. |
|
|
1098 |
Human STK11 / LKB1 Gene cDNA Clone (full-length ORF Clone)Human STK11 / LKB1 Gene cDNA Clone (full-length ORF Clone) |
|
|
1099 |
|
|
|
1100 |
Tools |
|
|
1101 |
(Free resource) (free) GeneMANIA |
|
|
1102 |
GeneMANIA |