--- a
+++ b/GeneID_6794.txt
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+STK11 serine/threonine kinase 11[Homo sapiens]
+Gene ID: 6794, updated on 20-Apr-2023
+
+
+SUMMARY
+-------------------------------------------------------------------------------------------------
+
+Official Symbol: STK11 (provided by HGNC)
+Official full name: serine/threonine kinase 11 (provided by HGNC)
+Primary source: HGNC:HGNC:11389
+See related: Ensembl:ENSG00000118046; MIM:602216; AllianceGenome:HGNC:11389
+Gene type: protein coding
+RefSeq status: REVIEWED
+Organism: Homo sapiens
+
+Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
+Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
+
+Also known as: PJS; LKB1; hLKB1
+
+Summary: The protein encoded by this gene is a serine/threonine kinase that regulates cell
+polarity and energy metabolism and functions as a tumor suppressor. Mutations in 
+this gene have been associated with the autosomal dominant Peutz-Jeghers
+syndrome, as well as with skin, pancreatic, and testicular cancers. [provided by 
+RefSeq, May 2022]
+
+Orthologsall (/gene/?Term=ortholog_gene_6794[group]), mouse (https://www.ncbi.nlm.nih.gov/gene/20869)
+
+GENOMIC CONTEXT
+-------------------------------------------------------------------------------------------------
+
+
+Location: 19p13.3
+
+Annotation release	Status	Assembly	Chromosome	Location
+-------------------------------------------------------------------------------------------------
+RS_2023_03	current	GRCh38.p14 (GCF_000001405.40)	19	NC_000019.10 (1205778..1228431) 
+RS_2023_03	current	T2T-CHM13v2.0 (GCF_009914755.1)	19	NC_060943.1 (1174325..1196989) 
+105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	19	NC_000019.9 (1205777..1228430) 
+Exont count: 12
+
+
+BIBLIOGRAPHY
+-------------------------------------------------------------------------------------------------
+
+
+Related Articles in PubMed
+
+1. The liver kinase B1 supports mammary epithelial morphogenesis by inhibiting
+critical factors that mediate epithelial-mesenchymal transition. Tzavlaki K, . J 
+Cell Physiol, 2023 Apr, PMID 36791282.
+2. LKB1 Loss Assessed by Immunohistochemistry as a Prognostic Marker to First-Line
+Therapy in Advanced Non-Small-Cell Lung Cancer. Avilés-Salas A, . Curr Oncol,
+2022 Dec 26, PMID 36661676., Free PMC Article(s): PMC9857995
+3. STK11 Inactivation Predicts Rapid Recurrence in Inoperable Early-Stage
+Non-Small-Cell Lung Cancer. Katipally RR, . JCO Precis Oncol, 2023 Jan, PMID
+36603171.
+4. A novel missense mutation of the STK11 gene in a Chinese family with
+Peutz-Jeghers syndrome. Yu Z, . BMC Gastroenterol, 2022 Dec 22, PMID 36550395., Free PMC Article(s): PMC9784088
+5. Liver kinase B1 in exosomes inhibits immune checkpoint programmed death ligand 1 
+and metastatic progression of intrahepatic cholangiocarcinoma. Liu Z, . Oncol
+Rep, 2022 Sep, PMID 35856436., Free PMC Article(s): PMC9350976
+6. LKB1 is the gatekeeper of carotid body chemosensing and the hypoxic ventilatory
+response. MacMillan S, . Commun Biol, 2022 Jun 29, PMID 35768580., Free PMC Article(s): PMC9243028
+<pre>
+PHENOTYPES
+-------------------------------------------------------------------------------------------------
+
+Review eQTL and phenotype association data in this region using PheGenI
+	http://www.ncbi.nlm.nih.gov/gap/PheGenI?chr=19&amp;from=1205777&amp;fromto=1205777+1228430&amp;tab=0
+
+Professional guidelines
+-------------------------------------------------------------------------------------------------
+Professional guideline
+	ACMG 2013		
+		The ACMG recommends that laboratories performing clinical sequencing seek and report mutations in STK11 that are pathogenic or expected to be pathogenic.
+			
+			Guideline(http://www.acmg.net/docs/ACMG_Releases_Highly-Anticipated_Recommendations_on_Incidental_Findings_in_Clinical_Exome_and_Genome_Sequencing.pdf)
+			PubMed(/pubmed/23788249)
+Associated conditions
+-------------------------------------------------------------------------------------------------
+Description	Tests
+-------------------------------------------------------------------------------------------------
+
+Carcinoma of pancreas
+	MedGen: C0235974 OMIM:  260350 GeneReviews: <span>Not available</span>	
+Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.
+	GeneReviews: <span>Not available</span>	
+Genome-wide association study of Alzheimer's disease with psychotic symptoms.
+	GeneReviews: <span>Not available</span>	
+Germ cell tumor of testis
+	MedGen: C1336708 OMIM:  273300 GeneReviews: <span>Not available</span>	
+Melanoma, cutaneous malignant, susceptibility to, 1
+	MedGen: C1835047 OMIM:  155600 GeneReviews: <span>Not available</span>	
+Peutz-Jeghers syndrome
+	MedGen: C0031269 OMIM:  175200 GeneReviews: Peutz-Jeghers Syndrome	
+
+Copy number response
+-------------------------------------------------------------------------------------------------
+Copy number response
+	Triplosensitivity		
+		No evidence available (Last evaluated 2021-11-10)
+			
+			ClinGen Genome Curation Page(https://www.ncbi.nlm.nih.gov/projects/dbvar/ISCA/isca_gene.cgi?sym=STK11)Haploinsufficency		
+		Sufficient evidence for dosage pathogenicity (Last evaluated 2021-11-10)
+			
+			ClinGen Genome Curation Page(https://www.ncbi.nlm.nih.gov/projects/dbvar/ISCA/isca_gene.cgi?sym=STK11)
+			PubMed(/pubmed/20623358,23892522,2563227,28231849)</pre>
+
+VARIATION
+-------------------------------------------------------------------------------------------------
+
+See variants in ClinVar, http://130.14.22.58/sites/gene/clinvar/?term=STK11[gene]
+See studies and variants in dbVar, http://130.14.22.58/sites/gene
+See Variation Viewer (GRCh37.p13), http://130.14.22.58/sites/gene/variation/view/?q=6794[geneid]&amp;assm=GCF_000001405.25
+See Variation Viewer (GRCh38), http://130.14.22.58/sites/gene/variation/view/?q=6794[geneid]<pre/><pre>
+Genotypes
+	See  SNP Geneview Report, http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2FSNP%2Fsnp_ref.cgi%3FlocusId%3D6794
+	See 1000 Genomes Browser (GCF_000001405.25), http://130.14.22.58/sites/gene/variation/tools/1000genomes/?q=6794[geneid]&amp;assm=GCF_000001405.25</pre>
+
+
+INTERACTION
+-------------------------------------------------------------------------------------------------
+
+Description of Gene Interaction table
+
+Product		Interactant	Other Gene    Complex	Source		Pubs
+-------------------------------------------------------------------------------------------------
+
+LKB1 phosphorylates MARK4.
+NP_000446.1    	NP_113605.2    	MARK4      		BIND		PMID: 14676191
+LKB1 interacts with AMPK-alpha.
+NP_000446.1    	NP_006243.2    	PRKAA2     		BIND		PMID: 14985505
+LKB1 autophosphorylates itself.
+NP_000446.1    	NP_000446.1    	STK11      		BIND		PMID: 14676191
+LKB1 phosphorylates PAPK.
+NP_000446.1    	NP_061041.2    	STRADB     		BIND		PMID: 14676191
+Q15831         	Q13315         	ATM        		HPRD		PMID: 12234250,11853558
+Q15831         	Q9Y376         	CAB39      		HPRD		PMID: 14676191
+Q15831         	Q16543         	CDC37      		HPRD		PMID: 12489981
+Q15831         	Q9P0L2         	MARK1      		HPRD		PMID: 14976552,14517247
+Q15831         	Q7KZI7         	MARK2      		HPRD		PMID: 14976552
+Q15831         	Q96L34         	MARK4      		HPRD		PMID: 14676191
+Q15831         	Q9Y3A3         	MOB4       		HPRD		PMID: 16169070
+Q15831         	Q8TEW0         	PARD3      		HPRD		PMID: 14676191
+Q15831         	P54646         	PRKAA2     		HPRD		PMID: 10642499
+Q15831         	P17612         	PRKACA     		HPRD		PMID: 11853558,11297520
+Q15831         	P60484         	PTEN       		HPRD		PMID: 15987703
+Q15831         	P51812         	RPS6KA3    		HPRD		PMID: 11853558,11297520
+Q15831         	O75582         	RPS6KA5    		HPRD		PMID: 11297520
+Q15831         	P23443         	RPS6KB1    		HPRD		PMID: 11853558,11297520
+Q15831         	P51532         	SMARCA4    		HPRD		PMID: 11445556
+Q15831         	Q9NRH2         	SNRK       		HPRD		PMID: 15733851
+Q15831         	Q15831         	STK11      		HPRD		PMID: 11668633
+Q15831         	LKB1 interacting protein 1	STK11IP    		HPRD		PMID: 11741830
+Q15831         	Protein kinase LYK5	STRADA     		HPRD		PMID: 12805220
+Q15831         	Q9C0K7         	STRADB     		HPRD		PMID: 14676191
+Q15831         	TNFAIP3 interacting protein 2	TNIP2      		HPRD		PMID: 12595760
+Q15831         	P04637         	TP53       		HPRD		PMID: 11430832
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:126860 	A2ML1      		BioGRID		PMID: 33961781
+FRET
+BioGRID:112670 	BioGRID:131028 	ABCB5      		BioGRID		PMID: 28205554
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:116784 	ABRAXAS2   		BioGRID		PMID: 33961781,28514442
+Two-hybrid
+BioGRID:112670 	BioGRID:119283 	ADIPOR1    		BioGRID		PMID: 25640309
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:120419 	AGGF1      		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:124393 	AJUBA      		BioGRID		PMID: 34591612
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:115445 	AKAP9      		BioGRID		PMID: 33961781
+FRET; Two-hybrid
+BioGRID:112670 	BioGRID:106710 	AKT1       		BioGRID		PMID: 28205554,24412244
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:111790 	ALDH18A1   		BioGRID		PMID: 34591612
+Two-hybrid
+BioGRID:112670 	BioGRID:106730 	ALDOB      		BioGRID		PMID: 24412244
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:106775 	AMY1C      		BioGRID		PMID: 33961781
+Two-hybrid
+BioGRID:112670 	BioGRID:115795 	ANP32B     		BioGRID		PMID: 24412244
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:106798 	ANXA1      		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:575558 	ANXA8      		BioGRID		PMID: 33961781
+Affinity Capture-Western
+BioGRID:112670 	BioGRID:107587 	AP2M1      		BioGRID		PMID: 20368287
+Reconstituted Complex
+BioGRID:112670 	BioGRID:106848 	APP        		BioGRID		PMID: 21832049
+FRET
+BioGRID:112670 	BioGRID:106864 	ARAF       		BioGRID		PMID: 28205554
+Two-hybrid
+BioGRID:112670 	BioGRID:106879 	ARG2       		BioGRID		PMID: 25640309
+Negative Genetic
+BioGRID:112670 	BioGRID:128219 	ARID2      		BioGRID		PMID: 35559673
+FRET
+BioGRID:112670 	BioGRID:106898 	ARNT       		BioGRID		PMID: 28205554
+Negative Genetic
+BioGRID:112670 	BioGRID:121948 	ATG101     		BioGRID		PMID: 35559673
+Phenotypic Suppression
+BioGRID:112670 	BioGRID:115787 	ATG7       		BioGRID		PMID: 33226137
+Negative Genetic
+BioGRID:112670 	BioGRID:122518 	ATG9A      		BioGRID		PMID: 35559673
+Affinity Capture-Western
+BioGRID:112670 	BioGRID:106962 	ATM        		BioGRID		PMID: 15713674
+FRET
+BioGRID:112670 	BioGRID:112666 	AURKA      		BioGRID		PMID: 28205554
+Two-hybrid
+BioGRID:112670 	BioGRID:198131 	Ap2m1      		BioGRID		PMID: 20368287
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:118855 	BABAM1     		BioGRID		PMID: 33961781
+Negative Genetic
+BioGRID:112670 	BioGRID:113647 	BAG6       		BioGRID		PMID: 35559673
+Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
+BioGRID:112670 	BioGRID:113911 	BAP1       		BioGRID		PMID: 32819560
+Two-hybrid
+BioGRID:112670 	BioGRID:120182 	BCAS3      		BioGRID		PMID: 25640309
+Negative Genetic
+BioGRID:112670 	BioGRID:115118 	BCLAF1     		BioGRID		PMID: 35559673
+FRET
+BioGRID:112670 	BioGRID:114226 	BECN1      		BioGRID		PMID: 28205554
+Negative Genetic
+BioGRID:112670 	BioGRID:121521 	BIRC6      		BioGRID		PMID: 35559673
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:126647 	BPIFA2     		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:123248 	BPIFB2     		BioGRID		PMID: 33961781
+FRET
+BioGRID:112670 	BioGRID:107141 	BRAF       		BioGRID		PMID: 28205554
+Negative Genetic
+BioGRID:112670 	BioGRID:122599 	BRCC3      		BioGRID		PMID: 35559673
+Negative Genetic
+BioGRID:112670 	BioGRID:122430 	BRD9       		BioGRID		PMID: 35559673
+Negative Genetic
+BioGRID:112670 	BioGRID:123841 	BRIP1      		BioGRID		PMID: 35559673
+Negative Genetic
+BioGRID:112670 	BioGRID:107160 	BTK        		BioGRID		PMID: 35559673
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:126409 	C5orf24    		BioGRID		PMID: 33961781,28514442
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:131603 	C6orf58    		BioGRID		PMID: 33961781
+Negative Genetic
+BioGRID:112670 	BioGRID:124367 	C8orf76    		BioGRID		PMID: 35559673
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:107220 	CA6        		BioGRID		PMID: 33961781
+Affinity Capture-MS; Affinity Capture-Western; Co-localization
+BioGRID:112670 	BioGRID:119696 	CAB39      		BioGRID		PMID: 35271311,34591612,33961781,32707033,31554794,31217475,28514442,25852190,25241761,20562859,15561763,14676191
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:123552 	CAB39L     		BioGRID		PMID: 33961781,28514442,26186194,20562859
+Two-hybrid
+BioGRID:112670 	BioGRID:107256 	CALM2      		BioGRID		PMID: 25640309
+Negative Genetic
+BioGRID:112670 	BioGRID:127632 	CAMSAP1    		BioGRID		PMID: 35559673
+FRET
+BioGRID:112670 	BioGRID:117156 	CBLC       		BioGRID		PMID: 28205554
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:122267 	CCDC136    		BioGRID		PMID: 25852190
+Two-hybrid
+BioGRID:112670 	BioGRID:1527673	CCDC180    		BioGRID		PMID: 24412244
+FRET
+BioGRID:112670 	BioGRID:107334 	CCND2      		BioGRID		PMID: 28205554
+FRET
+BioGRID:112670 	BioGRID:107338 	CCNE1      		BioGRID		PMID: 28205554
+FRET
+BioGRID:112670 	BioGRID:107398 	CD44       		BioGRID		PMID: 28205554
+Two-hybrid
+BioGRID:112670 	BioGRID:114125 	CDC14B     		BioGRID		PMID: 24412244
+Affinity Capture-MS; Affinity Capture-Western
+BioGRID:112670 	BioGRID:116312 	CDC37      		BioGRID		PMID: 34591612,33961781,32707033,21860411,20562859,14676191,14668798
+FRET
+BioGRID:112670 	BioGRID:107454 	CDK4       		BioGRID		PMID: 28205554
+FRET
+BioGRID:112670 	BioGRID:107456 	CDK6       		BioGRID		PMID: 28205554
+FRET
+BioGRID:112670 	BioGRID:107463 	CDKN2A     		BioGRID		PMID: 28205554
+FRET
+BioGRID:112670 	BioGRID:107464 	CDKN2B     		BioGRID		PMID: 28205554
+FRET
+BioGRID:112670 	BioGRID:107465 	CDKN2C     		BioGRID		PMID: 28205554
+Two-hybrid
+BioGRID:112670 	BioGRID:107500 	CFL2       		BioGRID		PMID: 25640309
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:114729 	COPS2      		BioGRID		PMID: 34591612,32707033
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:114103 	COPS3      		BioGRID		PMID: 34591612,33961781,32707033,25852190
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:119324 	COPS4      		BioGRID		PMID: 34591612,32707033,25852190
+Affinity Capture-MS; Affinity Capture-Western
+BioGRID:112670 	BioGRID:116183 	COPS5      		BioGRID		PMID: 34591612,30710502
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:116176 	COPS6      		BioGRID		PMID: 34591612,32707033
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:119130 	COPS7A     		BioGRID		PMID: 34591612
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:122237 	COPS7B     		BioGRID		PMID: 34591612
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:116124 	COPS8      		BioGRID		PMID: 34591612,32707033
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:119069 	CRNN       		BioGRID		PMID: 33961781
+Two-hybrid
+BioGRID:112670 	BioGRID:107798 	CRY2       		BioGRID		PMID: 25640309
+Negative Genetic
+BioGRID:112670 	BioGRID:107836 	CSNK1A1    		BioGRID		PMID: 35559673
+Synthetic Lethality
+BioGRID:112670 	BioGRID:107841 	CSNK2A1    		BioGRID		PMID: 27453043
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:107851 	CST1       		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:107852 	CST2       		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:107854 	CST4       		BioGRID		PMID: 33961781
+Two-hybrid
+BioGRID:112670 	BioGRID:107888 	CTSB       		BioGRID		PMID: 25640309
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:114031 	CUL2       		BioGRID		PMID: 34591612
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:114028 	CUL4B      		BioGRID		PMID: 32707033
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:115159 	CUL7       		BioGRID		PMID: 33961781
+Two-hybrid
+BioGRID:112670 	BioGRID:107919 	CYLC2      		BioGRID		PMID: 24412244
+Two-hybrid
+BioGRID:112670 	BioGRID:107958 	CYP17A1    		BioGRID		PMID: 25640309
+Two-hybrid
+BioGRID:112670 	BioGRID:608722 	D2HGDH     		BioGRID		PMID: 25640309
+FRET
+BioGRID:112670 	BioGRID:107972 	DACH1      		BioGRID		PMID: 28205554
+Negative Genetic
+BioGRID:112670 	BioGRID:121945 	DHX35      		BioGRID		PMID: 35559673
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:108095 	DMBT1      		BioGRID		PMID: 33961781
+Negative Genetic
+BioGRID:112670 	BioGRID:108112 	DNASE1     		BioGRID		PMID: 35559673
+Negative Genetic
+BioGRID:112670 	BioGRID:125472 	DNTTIP1    		BioGRID		PMID: 35559673
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:108164 	DSG3       		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:108189 	DVL2       		BioGRID		PMID: 28514442
+Two-hybrid
+BioGRID:112670 	BioGRID:108238 	EEF1A2     		BioGRID		PMID: 25640309
+Affinity Capture-Western
+BioGRID:112670 	BioGRID:108286 	EIF2B1     		BioGRID		PMID: 20368287
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:114423 	ENDOU      		BioGRID		PMID: 33961781
+FRET
+BioGRID:112670 	BioGRID:108288 	EPHA2      		BioGRID		PMID: 28205554
+FRET
+BioGRID:112670 	BioGRID:108376 	ERBB2      		BioGRID		PMID: 28205554
+Two-hybrid
+BioGRID:112670 	BioGRID:118096 	ERLEC1     		BioGRID		PMID: 25640309
+Affinity Capture-Western; Biochemical Activity; Two-hybrid
+BioGRID:112670 	BioGRID:108419 	ETV4       		BioGRID		PMID: 21150337,16912160
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:108426 	EVPL       		BioGRID		PMID: 33961781
+Two-hybrid
+BioGRID:112670 	BioGRID:229070 	Eif2b1     		BioGRID		PMID: 20368287
+Two-hybrid
+BioGRID:112670 	BioGRID:116659 	FAIM2      		BioGRID		PMID: 25640309
+Negative Genetic
+BioGRID:112670 	BioGRID:123086 	FAM106A    		BioGRID		PMID: 35559673
+Negative Genetic
+BioGRID:112670 	BioGRID:108472 	FANCA      		BioGRID		PMID: 35559673
+Negative Genetic
+BioGRID:112670 	BioGRID:108483 	FANCF      		BioGRID		PMID: 35559673
+Two-hybrid
+BioGRID:112670 	BioGRID:108497 	FBP1       		BioGRID		PMID: 24412244
+Two-hybrid
+BioGRID:112670 	BioGRID:114317 	FBP2       		BioGRID		PMID: 24412244
+Affinity Capture-Western
+BioGRID:112670 	BioGRID:126870 	FBXL14     		BioGRID		PMID: 29601127
+Affinity Capture-Western; Co-localization
+BioGRID:112670 	BioGRID:117649 	FBXO22     		BioGRID		PMID: 31217475
+Negative Genetic
+BioGRID:112670 	BioGRID:127320 	FBXO41     		BioGRID		PMID: 35559673
+Negative Genetic
+BioGRID:112670 	BioGRID:119962 	FBXO42     		BioGRID		PMID: 35559673
+Negative Genetic
+BioGRID:112670 	BioGRID:116887 	FBXW11     		BioGRID		PMID: 35559673
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:117645 	FBXW8      		BioGRID		PMID: 33961781
+FRET
+BioGRID:112670 	BioGRID:108555 	FGFR4      		BioGRID		PMID: 28205554
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:108578 	FKBP4      		BioGRID		PMID: 34591612
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:108579 	FKBP5      		BioGRID		PMID: 34591612,33961781,32707033,28514442,25852190,20562859,14676191
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:108601 	FLG        		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:122669 	FYCO1      		BioGRID		PMID: 33961781
+FRET
+BioGRID:112670 	BioGRID:119489 	FZR1       		BioGRID		PMID: 28205554
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:108887 	GARS1      		BioGRID		PMID: 34591612
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:127864 	GBP6       		BioGRID		PMID: 33961781
+FRET
+BioGRID:112670 	BioGRID:124182 	GLIS2      		BioGRID		PMID: 28205554
+Two-hybrid
+BioGRID:112670 	BioGRID:115325 	GNPDA1     		BioGRID		PMID: 25640309
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:109131 	GPS1       		BioGRID		PMID: 34591612,32707033
+FRET
+BioGRID:112670 	BioGRID:109168 	GRM1       		BioGRID		PMID: 28205554
+Affinity Capture-Western
+BioGRID:112670 	BioGRID:109187 	GSK3B      		BioGRID		PMID: 22270359
+Negative Genetic
+BioGRID:112670 	BioGRID:114937 	GTPBP1     		BioGRID		PMID: 35559673
+Negative Genetic
+BioGRID:112670 	BioGRID:120097 	GTPBP2     		BioGRID		PMID: 35559673
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:109268 	H2AX       		BioGRID		PMID: 25852190
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:109284 	HAL        		BioGRID		PMID: 33961781
+Affinity Capture-Western; Biochemical Activity
+BioGRID:112670 	BioGRID:114438 	HERC2      		BioGRID		PMID: 27259994
+FRET
+BioGRID:112670 	BioGRID:109330 	HGF        		BioGRID		PMID: 28205554
+FRET
+BioGRID:112670 	BioGRID:109338 	HIF1A      		BioGRID		PMID: 28205554
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:109345 	HK1        		BioGRID		PMID: 34591612
+Negative Genetic
+BioGRID:112670 	BioGRID:109465 	HOXC9      		BioGRID		PMID: 35559673
+Two-hybrid
+BioGRID:112670 	BioGRID:109501 	HRAS       		BioGRID		PMID: 24412244
+Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western
+BioGRID:112670 	BioGRID:109552 	HSP90AA1   		BioGRID		PMID: 33961781,32707033,28514442,22939624,21860411,14676191,14668798
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:109555 	HSP90AA4P  		BioGRID		PMID: 33961781,28514442
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:610599 	HSP90AA5P  		BioGRID		PMID: 33961781,28514442
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:109558 	HSP90AB1   		BioGRID		PMID: 33961781,32707033,28514442
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:109559 	HSP90AB3P  		BioGRID		PMID: 33961781,28514442
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:576430 	HSP90AB4P  		BioGRID		PMID: 33961781,28514442
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:109535 	HSPA1A     		BioGRID		PMID: 14676191
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:118149 	HTATSF1    		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:120824 	IARS2      		BioGRID		PMID: 34591612
+Two-hybrid
+BioGRID:112670 	BioGRID:109707 	IGFBP3     		BioGRID		PMID: 24412244
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:109714 	IGHA1      		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:109715 	IGHA2      		BioGRID		PMID: 33961781
+Negative Genetic
+BioGRID:112670 	BioGRID:114089 	IKBKG      		BioGRID		PMID: 35559673
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:109772 	IL1RN      		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:129701 	INO80E     		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:109916 	IVD        		BioGRID		PMID: 34591612,28514442
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:109917 	IVL        		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:109732 	JCHAIN     		BioGRID		PMID: 33961781
+Negative Genetic
+BioGRID:112670 	BioGRID:116105 	JTB        		BioGRID		PMID: 35559673
+FRET
+BioGRID:112670 	BioGRID:108918 	KAT2A      		BioGRID		PMID: 28205554
+FRET
+BioGRID:112670 	BioGRID:116204 	KDELR2     		BioGRID		PMID: 28205554
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:115035 	KDM4A      		BioGRID		PMID: 33961781,28514442
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:114873 	KIF23      		BioGRID		PMID: 14676191
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:111636 	KLK10      		BioGRID		PMID: 33961781
+Two-hybrid
+BioGRID:112670 	BioGRID:111631 	KLK7       		BioGRID		PMID: 25640309
+Negative Genetic
+BioGRID:112670 	BioGRID:110038 	KPNA4      		BioGRID		PMID: 35559673
+Affinity Capture-Western
+BioGRID:112670 	BioGRID:120336 	LAMTOR1    		BioGRID		PMID: 34821530
+FRET
+BioGRID:112670 	BioGRID:117727 	LATS2      		BioGRID		PMID: 28205554
+Two-hybrid
+BioGRID:112670 	BioGRID:119354 	LEF1       		BioGRID		PMID: 24412244
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:110175 	LIMS1      		BioGRID		PMID: 14676191
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:110201 	LOXL2      		BioGRID		PMID: 34591612
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:110208 	LPP        		BioGRID		PMID: 34591612
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:110235 	LTF        		BioGRID		PMID: 33961781
+Two-hybrid
+BioGRID:112670 	BioGRID:117985 	LYPD3      		BioGRID		PMID: 25640309
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:110247 	LYZ        		BioGRID		PMID: 33961781
+Negative Genetic
+BioGRID:112670 	BioGRID:116348 	LZTS1      		BioGRID		PMID: 35559673
+Synthetic Lethality; Two-hybrid
+BioGRID:112670 	BioGRID:111590 	MAP2K1     		BioGRID		PMID: 27453043,24412244
+Affinity Capture-Western; FRET
+BioGRID:112670 	BioGRID:111592 	MAP2K3     		BioGRID		PMID: 28628118,28205554
+FRET
+BioGRID:112670 	BioGRID:111593 	MAP2K5     		BioGRID		PMID: 28205554
+FRET
+BioGRID:112670 	BioGRID:111594 	MAP2K6     		BioGRID		PMID: 28205554
+FRET
+BioGRID:112670 	BioGRID:110381 	MAP3K5     		BioGRID		PMID: 28205554
+FRET
+BioGRID:112670 	BioGRID:107819 	MAPK14     		BioGRID		PMID: 28205554
+Two-hybrid
+BioGRID:112670 	BioGRID:111581 	MAPK3      		BioGRID		PMID: 24412244
+Two-hybrid
+BioGRID:112670 	BioGRID:116581 	MAPRE1     		BioGRID		PMID: 24552808
+Biochemical Activity
+BioGRID:112670 	BioGRID:108326 	MARK2      		BioGRID		PMID: 16396636
+Affinity Capture-Western
+BioGRID:112670 	BioGRID:121760 	MARK4      		BioGRID		PMID: 14676191
+Negative Genetic
+BioGRID:112670 	BioGRID:129033 	MCM9       		BioGRID		PMID: 35559673
+Affinity Capture-Western; FRET
+BioGRID:112670 	BioGRID:110358 	MDM2       		BioGRID		PMID: 35513074,28205554
+FRET
+BioGRID:112670 	BioGRID:110391 	MET        		BioGRID		PMID: 28205554
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:119275 	MLXIPL     		BioGRID		PMID: 34461288
+Affinity Capture-MS; Co-localization
+BioGRID:112670 	BioGRID:122103 	MMS19      		BioGRID		PMID: 34591612
+Two-hybrid
+BioGRID:112670 	BioGRID:110481 	MOCS2      		BioGRID		PMID: 25640309
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:110493 	MPO        		BioGRID		PMID: 33961781
+Negative Genetic
+BioGRID:112670 	BioGRID:110498 	MPV17      		BioGRID		PMID: 35559673
+Negative Genetic
+BioGRID:112670 	BioGRID:125820 	MTFMT      		BioGRID		PMID: 35559673
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:114560 	MTMR4      		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:608337 	MUC5B      		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:110676 	MUC7       		BioGRID		PMID: 33961781
+FRET
+BioGRID:112670 	BioGRID:110694 	MYC        		BioGRID		PMID: 28205554
+Two-hybrid
+BioGRID:112670 	BioGRID:119921 	NANS       		BioGRID		PMID: 24412244
+Two-hybrid
+BioGRID:112670 	BioGRID:106528 	NAT2       		BioGRID		PMID: 25640309
+Two-hybrid
+BioGRID:112670 	BioGRID:110632 	ND2        		BioGRID		PMID: 25640309
+Negative Genetic
+BioGRID:112670 	BioGRID:110792 	NDUFB6     		BioGRID		PMID: 35559673
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:114594 	NEMF       		BioGRID		PMID: 28514442
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:115983 	NES        		BioGRID		PMID: 33961781
+FRET
+BioGRID:112670 	BioGRID:110844 	NF2        		BioGRID		PMID: 28205554
+Negative Genetic
+BioGRID:112670 	BioGRID:117008 	OTP        		BioGRID		PMID: 35559673
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:116413 	PACSIN2    		BioGRID		PMID: 33961781
+FRET
+BioGRID:112670 	BioGRID:111182 	PDGFRA     		BioGRID		PMID: 28205554
+Negative Genetic
+BioGRID:112670 	BioGRID:116848 	PDS5A      		BioGRID		PMID: 35559673
+Negative Genetic
+BioGRID:112670 	BioGRID:117125 	PDSS1      		BioGRID		PMID: 35559673
+Two-hybrid
+BioGRID:112670 	BioGRID:121330 	PDXP       		BioGRID		PMID: 25640309
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:111788 	PEX5       		BioGRID		PMID: 33961781
+Two-hybrid
+BioGRID:112670 	BioGRID:122561 	PHF23      		BioGRID		PMID: 25640309
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:111302 	PIGR       		BioGRID		PMID: 33961781
+FRET
+BioGRID:112670 	BioGRID:111308 	PIK3CA     		BioGRID		PMID: 28205554
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:111322 	PIP4K2A    		BioGRID		PMID: 33961781,32707033,28514442
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:113985 	PIP4K2B    		BioGRID		PMID: 32707033
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:122928 	PIP4K2C    		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:114074 	PKP4       		BioGRID		PMID: 34591612
+Two-hybrid
+BioGRID:112670 	BioGRID:117173 	PLD3       		BioGRID		PMID: 25640309
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:126828 	PLEKHA7    		BioGRID		PMID: 34591612
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:123048 	POF1B      		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:111488 	PPL        		BioGRID		PMID: 33961781
+Two-hybrid
+BioGRID:112670 	BioGRID:111508 	PPP2CB     		BioGRID		PMID: 24412244
+Negative Genetic
+BioGRID:112670 	BioGRID:120344 	PPP2R3C    		BioGRID		PMID: 35559673
+Affinity Capture-Western; Biochemical Activity; Two-hybrid
+BioGRID:112670 	BioGRID:111549 	PRKAA1     		BioGRID		PMID: 31995728,31217475,16912160
+Co-localization
+BioGRID:112670 	BioGRID:111550 	PRKAA2     		BioGRID		PMID: 25241761
+Co-localization
+BioGRID:112670 	BioGRID:111558 	PRKAG1     		BioGRID		PMID: 31983282
+Negative Genetic
+BioGRID:112670 	BioGRID:114143 	PRKRA      		BioGRID		PMID: 35559673
+Two-hybrid
+BioGRID:112670 	BioGRID:118887 	PRSS50     		BioGRID		PMID: 25640309
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:111638 	PRTN3      		BioGRID		PMID: 33961781
+Negative Genetic
+BioGRID:112670 	BioGRID:114872 	PSMF1      		BioGRID		PMID: 35559673
+Affinity Capture-Western; Biochemical Activity; Co-localization; Two-hybrid
+BioGRID:112670 	BioGRID:111700 	PTEN       		BioGRID		PMID: 15987703
+Two-hybrid
+BioGRID:112670 	BioGRID:111856 	RASA1      		BioGRID		PMID: 24412244
+FRET
+BioGRID:112670 	BioGRID:116356 	RASSF1     		BioGRID		PMID: 28205554
+Two-hybrid
+BioGRID:112670 	BioGRID:116828 	RHOBTB2    		BioGRID		PMID: 25640309
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:121946 	RIC8A      		BioGRID		PMID: 34591612
+Affinity Capture-RNA
+BioGRID:112670 	BioGRID:117121 	RIGI       		BioGRID		PMID: 32513696
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:120896 	RIOK2      		BioGRID		PMID: 33961781
+Affinity Capture-Western
+BioGRID:112670 	BioGRID:123598 	RNF146     		BioGRID		PMID: 31554794
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:122783 	RPAP3      		BioGRID		PMID: 14676191
+Negative Genetic
+BioGRID:112670 	BioGRID:121820 	RPRD1B     		BioGRID		PMID: 35559673
+Co-localization
+BioGRID:112670 	BioGRID:112112 	RPS6KB1    		BioGRID		PMID: 25241761
+Two-hybrid
+BioGRID:112670 	BioGRID:121504 	S100A14    		BioGRID		PMID: 25640309
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:112188 	S100A9     		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:114324 	SCEL       		BioGRID		PMID: 33961781
+Negative Genetic
+BioGRID:112670 	BioGRID:112291 	SDHB       		BioGRID		PMID: 35559673
+Two-hybrid
+BioGRID:112670 	BioGRID:116015 	SEPTIN9    		BioGRID		PMID: 25640309
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:108307 	SERPINB1   		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:111293 	SERPINB13  		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:112223 	SERPINB3   		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:112224 	SERPINB4   		BioGRID		PMID: 33961781
+Affinity Capture-MS; Two-hybrid
+BioGRID:112670 	BioGRID:111286 	SERPINB5   		BioGRID		PMID: 33961781,25640309
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:118845 	SETD2      		BioGRID		PMID: 33961781
+Biochemical Activity
+BioGRID:112670 	BioGRID:127260 	SIK1       		BioGRID		PMID: 16396636
+Affinity Capture-Western; Biochemical Activity
+BioGRID:112670 	BioGRID:116983 	SIRT1      		BioGRID		PMID: 27259994,18687677
+Negative Genetic
+BioGRID:112670 	BioGRID:124002 	SLC25A33   		BioGRID		PMID: 35559673
+Negative Genetic
+BioGRID:112670 	BioGRID:115726 	SLC30A9    		BioGRID		PMID: 35559673
+FRET
+BioGRID:112670 	BioGRID:110261 	SMAD1      		BioGRID		PMID: 28205554
+Affinity Capture-MS; Affinity Capture-Western; FRET; Reconstituted Complex
+BioGRID:112670 	BioGRID:112481 	SMARCA4    		BioGRID		PMID: 28205554,14676191,11445556
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:112483 	SMARCC1    		BioGRID		PMID: 14676191
+Affinity Capture-Western
+BioGRID:112670 	BioGRID:112499 	SNAI1      		BioGRID		PMID: 29601127
+Biochemical Activity
+BioGRID:112670 	BioGRID:120211 	SNRK       		BioGRID		PMID: 15733851
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:119535 	SNX9       		BioGRID		PMID: 33961781
+Negative Genetic
+BioGRID:112670 	BioGRID:119936 	SOX18      		BioGRID		PMID: 35559673
+FRET
+BioGRID:112670 	BioGRID:112542 	SOX4       		BioGRID		PMID: 28205554
+Two-hybrid
+BioGRID:112670 	BioGRID:117335 	SPDEF      		BioGRID		PMID: 16912160
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:112585 	SPRR3      		BioGRID		PMID: 33961781
+Two-hybrid
+BioGRID:112670 	BioGRID:112645 	ST14       		BioGRID		PMID: 25640309
+FRET
+BioGRID:112670 	BioGRID:112670 	STK11      		BioGRID		PMID: 28205554
+Affinity Capture-Western
+BioGRID:112670 	BioGRID:125352 	STK11IP    		BioGRID		PMID: 11741830
+Two-hybrid
+BioGRID:112670 	BioGRID:114011 	STK24      		BioGRID		PMID: 25640309
+Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Co-localization; Reconstituted Complex; Two-hybrid
+BioGRID:112670 	BioGRID:124934 	STRADA     		BioGRID		PMID: 35271311,34591612,33961781,32707033,31554794,28514442,25852190,25241761,21860411,20562859,15561763,14676191,12805220
+Affinity Capture-MS; Biochemical Activity
+BioGRID:112670 	BioGRID:120668 	STRADB     		BioGRID		PMID: 35271311,34591612,33961781,32707033,28514442,20562859,14676191
+Affinity Capture-Western
+BioGRID:112670 	BioGRID:115563 	STUB1      		BioGRID		PMID: 21860411
+Two-hybrid
+BioGRID:112670 	BioGRID:120346 	STX17      		BioGRID		PMID: 24412244
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:112689 	SULT2B1    		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:112697 	SUPT5H     		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:112698 	SUPT6H     		BioGRID		PMID: 33961781
+Two-hybrid
+BioGRID:112670 	BioGRID:120889 	TBC1D23    		BioGRID		PMID: 21516116
+Two-hybrid
+BioGRID:112670 	BioGRID:116994 	TDRD7      		BioGRID		PMID: 24412244
+FRET
+BioGRID:112670 	BioGRID:114041 	TEAD2      		BioGRID		PMID: 28205554
+FRET
+BioGRID:112670 	BioGRID:112874 	TERT       		BioGRID		PMID: 28205554
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:112909 	TGM1       		BioGRID		PMID: 33961781
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:112911 	TGM3       		BioGRID		PMID: 33961781
+Two-hybrid
+BioGRID:112670 	BioGRID:112921 	THOP1      		BioGRID		PMID: 25640309
+Two-hybrid
+BioGRID:112670 	BioGRID:112925 	THRSP      		BioGRID		PMID: 25640309
+FRET
+BioGRID:112670 	BioGRID:112986 	TNFRSF1A   		BioGRID		PMID: 28205554
+Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid
+BioGRID:112670 	BioGRID:122573 	TNIP2      		BioGRID		PMID: 27609421,12753905,12595760
+Affinity Capture-Western
+BioGRID:112670 	BioGRID:114207 	TNKS       		BioGRID		PMID: 31554794
+Affinity Capture-Western
+BioGRID:112670 	BioGRID:123257 	TNKS2      		BioGRID		PMID: 31554794
+Affinity Capture-MS; Affinity Capture-Western; FRET
+BioGRID:112670 	BioGRID:113010 	TP53       		BioGRID		PMID: 33961781,28205554,11430832
+Affinity Capture-Western
+BioGRID:112670 	BioGRID:114181 	TP63       		BioGRID		PMID: 21150337
+Two-hybrid
+BioGRID:112670 	BioGRID:113500 	TRIM25     		BioGRID		PMID: 25640309
+Two-hybrid
+BioGRID:112670 	BioGRID:119593 	TRMO       		BioGRID		PMID: 24412244
+Negative Genetic
+BioGRID:112670 	BioGRID:113100 	TSC2       		BioGRID		PMID: 35559673
+Two-hybrid
+BioGRID:112670 	BioGRID:113102 	TSG101     		BioGRID		PMID: 25640309
+Two-hybrid
+BioGRID:112670 	BioGRID:113603 	TUBA1A     		BioGRID		PMID: 25640309
+Two-hybrid
+BioGRID:112670 	BioGRID:115655 	TUBB4A     		BioGRID		PMID: 25640309
+Negative Genetic
+BioGRID:112670 	BioGRID:113149 	TYMS       		BioGRID		PMID: 35559673
+Biochemical Activity
+BioGRID:112670 	BioGRID:113170 	UBE2D2     		BioGRID		PMID: 21860411
+Affinity Capture-Western
+BioGRID:112670 	BioGRID:121973 	UBE2O      		BioGRID		PMID: 31900314
+Negative Genetic
+BioGRID:112670 	BioGRID:118858 	UBE2T      		BioGRID		PMID: 35559673
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:113866 	USP11      		BioGRID		PMID: 14676191
+Two-hybrid
+BioGRID:112670 	BioGRID:112804 	VPS72      		BioGRID		PMID: 25640309
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:121649 	WDR48      		BioGRID		PMID: 19615732
+Affinity Capture-Western
+BioGRID:112670 	BioGRID:116350 	WDR6       		BioGRID		PMID: 17216128
+FRET
+BioGRID:112670 	BioGRID:113327 	WT1        		BioGRID		PMID: 28205554
+Two-hybrid
+BioGRID:112670 	BioGRID:113344 	XPA        		BioGRID		PMID: 24412244
+Negative Genetic
+BioGRID:112670 	BioGRID:119655 	YPEL5      		BioGRID		PMID: 35559673
+FRET
+BioGRID:112670 	BioGRID:113364 	YWHAG      		BioGRID		PMID: 28205554
+Affinity Capture-MS
+BioGRID:112670 	BioGRID:125855 	ZG16B      		BioGRID		PMID: 33961781
+Two-hybrid
+BioGRID:112670 	BioGRID:113528 	ZNF189     		BioGRID		PMID: 24412244
+Two-hybrid
+BioGRID:112670 	BioGRID:116536 	ZNF510     		BioGRID		PMID: 24412244
+
+GENERAL GENE INFO
+-------------------------------------------------------------------------------------------------
+
+Marker
+	REU1905              	(e-PCR)	Links:UniSTS:257089
+	RH104368             	(e-PCR)	Links:UniSTS:98693
+	Stk11                	(e-PCR), detects polymorphism	Links:UniSTS:546518
+
+
+Homology
+	Homologs of the STK11 gene
+		The STK11 gene is conserved in chimpanzee, Rhesus monkey, dog, mouse, rat, chicken, zebrafish, mosquito, C.elegans, and frog.
+	Orthologs from Annotation Pipeline (/gene/?Term=ortholog_gene_6794[group]): 
+	Orthologs
+
+Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
+
+Function				      GO ID		Evidence
+-------------------------------------------------------------------------------------------------
+enables ATP binding                           GO:0000000	PMID: 12805220
+enables LRR domain binding                    GO:0000000	-
+enables magnesium ion binding                 GO:0000000	PMID: 12805220
+enables p53 binding                           GO:0000000	PMID: 11430832
+enables protein binding                       GO:0000000	PMID: 12595760,12753905,12805220,14676191,17216128,19274086,19513107,19892943,20562859,22575644,22939624,24362629,25036637,25241761,25329316,25852190,26479318,28514442,32707033,34591612
+enables protein kinase activator activit...   GO:0000000	PMID: 19892943
+enables protein serine kinase activity        GO:0000000	-
+enables protein serine/threonine kinase ...   GO:0000000	PMID: 21873635
+enables protein serine/threonine kinase ...   GO:0000000	PMID: 11430832,12805220,19892943
+enables protein serine/threonine kinase ...   GO:0000000	-
+enables protein-containing complex bindi...   GO:0000000	-
+
+Processs				      GO ID		Evidence
+-------------------------------------------------------------------------------------------------
+involved_in DNA damage response               GO:0000000	PMID: 21873635
+involved_in DNA damage response               GO:0000000	PMID: 25329316
+acts_upstream_of_negative_effect G1 to G...   GO:0000000	PMID: 17216128
+acts_upstream_of_negative_effect G1 to G...   GO:0000000	PMID: 12805220
+involved_in Golgi localization                GO:0000000	-
+involved_in T cell receptor signaling pa...   GO:0000000	-
+involved_in activation of protein kinase...   GO:0000000	PMID: 19892943
+involved_in activation of protein kinase...   GO:0000000	PMID: 15731909
+involved_in activation of protein kinase...   GO:0000000	-
+involved_in anoikis                           GO:0000000	PMID: 19622832
+involved_in autophagy                         GO:0000000	-
+involved_in axonogenesis                      GO:0000000	-
+involved_in cellular response to UV-B         GO:0000000	PMID: 25329316
+involved_in dendrite extension                GO:0000000	-
+involved_in epithelial cell proliferatio...   GO:0000000	-
+involved_in establishment of cell polari...   GO:0000000	PMID: 21873635
+involved_in establishment of cell polari...   GO:0000000	PMID: 24643070
+involved_in establishment of cell polari...   GO:0000000	-
+involved_in glucose homeostasis               GO:0000000	-
+involved_in intrinsic apoptotic signalin...   GO:0000000	PMID: 11430832
+involved_in negative regulation of TORC1...   GO:0000000	PMID: 23878245
+involved_in negative regulation of canon...   GO:0000000	PMID: 15731909
+involved_in negative regulation of cell ...   GO:0000000	-
+involved_in negative regulation of cell ...   GO:0000000	PMID: 17216128,25329316
+involved_in negative regulation of cold-...   GO:0000000	PMID: 27461402
+involved_in negative regulation of epith...   GO:0000000	-
+involved_in peptidyl-threonine phosphory...   GO:0000000	PMID: 12805220
+involved_in positive regulation of autop...   GO:0000000	PMID: 23878245
+involved_in positive regulation of axono...   GO:0000000	-
+involved_in positive regulation of gluco...   GO:0000000	-
+involved_in positive regulation of prote...   GO:0000000	-
+involved_in positive regulation of trans...   GO:0000000	PMID: 18311138
+involved_in positive regulation of vesic...   GO:0000000	PMID: 21873635
+involved_in positive regulation of vesic...   GO:0000000	PMID: 24643070
+involved_in positive thymic T cell selec...   GO:0000000	-
+involved_in protein autophosphorylation       GO:0000000	PMID: 11430832
+involved_in protein dephosphorylation         GO:0000000	PMID: 15731909
+involved_in protein localization to nucl...   GO:0000000	-
+involved_in protein phosphorylation           GO:0000000	PMID: 21873635
+involved_in protein phosphorylation           GO:0000000	PMID: 12805220,25329316
+involved_in regulation of Wnt signaling ...   GO:0000000	PMID: 21873635
+involved_in regulation of cell cycle          GO:0000000	-
+involved_in regulation of cell growth         GO:0000000	-
+involved_in regulation of dendrite morph...   GO:0000000	-
+involved_in regulation of protein kinase...   GO:0000000	-
+involved_in regulation of signal transdu...   GO:0000000	-
+involved_in response to activity              GO:0000000	-
+involved_in response to glucagon              GO:0000000	-
+involved_in response to ionizing radiati...   GO:0000000	-
+involved_in response to lipid                 GO:0000000	-
+involved_in response to thyroid hormone       GO:0000000	-
+involved_in signal transduction               GO:0000000	PMID: 21873635
+involved_in spermatogenesis                   GO:0000000	-
+involved_in tissue homeostasis                GO:0000000	-
+involved_in vasculature development           GO:0000000	-
+
+Component				      GO ID		Evidence
+-------------------------------------------------------------------------------------------------
+located_in Z disc                             GO:0000000	-
+is_active_in cytoplasm                        GO:0000000	PMID: 21873635
+located_in cytoplasm                          GO:0000000	PMID: 11430832,12805220,14517248,17216128,18854309
+located_in cytoplasm                          GO:0000000	-
+located_in cytosol                            GO:0000000	-
+located_in cytosol                            GO:0000000	-
+located_in cytosol                            GO:0000000	-
+located_in extracellular exosome              GO:0000000	PMID: 19056867
+part_of intracellular protein-containing...   GO:0000000	PMID: 12805220
+located_in membrane                           GO:0000000	-
+located_in mitochondrion                      GO:0000000	PMID: 11430832
+located_in nucleoplasm                        GO:0000000	-
+located_in nucleoplasm                        GO:0000000	-
+is_active_in nucleus                          GO:0000000	PMID: 21873635
+located_in nucleus                            GO:0000000	PMID: 12805220,18854309
+part_of serine/threonine protein kinase ...   GO:0000000	PMID: 19892943
+part_of serine/threonine protein kinase ...   GO:0000000	-
+
+GENERAL PROTEIN INFORMATION
+-------------------------------------------------------------------------------------------------
+Preferred Names
+	serine/threonine-protein kinase STK11
+Names
+	liver kinase B1
+	polarization-related protein LKB1
+	renal carcinoma antigen NY-REN-19
+	serine/threonine-protein kinase 11
+	serine/threonine-protein kinase LKB1
+NP_000446.1
+	EC 2.7.11.1
+NP_001394184.1
+	EC 2.7.11.1
+
+NCBI REFERENCE SEQUENCES (RefSeq)
+-------------------------------------------------------------------------------------------------
+
+RefSeqs maintained independently of Annotated Genomes
+
+These reference sequences exist independently of genome builds.
+These reference sequences are curated independently of the genome annotation cycle, 
+so their versions may not match the RefSeq versions in the current genome build. 
+Identify version mismatches by comparing the version of the RefSeq in this section to 
+the one reported in Genomic regions, transcripts, and products section above.
+
+	Genomic
+		NG_007460.2 RefSeqGene
+		Range   	21392..44028
+		Download	GenBank FASTA Sequence Viewer (Graphics) 
+
+
+
+	mRNA and Protein(s) 
+
+	NM_000455.5 → NP_000446.1  REVIEWEDserine/threonine-protein kinase STK11 isoform 1
+
+	See proteins identical to NP_000446.1 at http://130.14.22.58/ipg/NP_000446.1/
+
+	Source sequence(s): AC011544, BC007981, BC019334, BM993274, BQ222023, BU174122, BU739451 
+	  Consensus CDS: CCDS45896.1
+	  UniProtKB/TrEMBL: A0A0S2Z4D1
+	  UniProtKB/Swiss-Prot: E7EW76
+	  UniProtKB/Swiss-Prot: Q15831
+
+	Related Ensembl: ENSP00000324856.6, ENST00000326873.12
+	  Conserved Domains (1)summary
+		cd14119: 
+		Location:55 - 309
+		STKc_LKB1; Catalytic domain of the Serine/Threonine kinase, Liver Kinase B1
+
+	NM_001407255.1 → NP_001394184.1  REVIEWEDserine/threonine-protein kinase STK11 isoform 2
+	Source sequence(s): AC011544 
+
+	RNA
+
+		NR_176325.1 RNA Sequence
+		Source sequence(s): AC004221, AC011544 
+
+RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_03
+The following sections contain reference sequences that belong to a specific genome build. 
+This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which 
+this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both 
+reference and alternate assemblies. Model RNAs and proteins are also reported here.
+
+Reference GRCh38.p14 Primary Assembly
+
+	Genomic
+		NC_000019.10 Reference GRCh38.p14 Primary Assembly
+		Range   	1205777..1228430
+		Download	GenBank FASTA Sequence Viewer (Graphics) 
+
+Alternate T2T-CHM13v2.0
+
+	Genomic
+		NC_060943.1 Alternate T2T-CHM13v2.0
+		Range   	1174324..1196988
+		Download	GenBank FASTA Sequence Viewer (Graphics) 
+
+
+
+RELATED SEQUENCES
+-------------------------------------------------------------------------------------------------
+
+Nucleotide			Protein
+-------------------------------------------------------------------------------------------------
+genomic             		AC004221.2	AAF97257.1
+genomic             		AC011544.6(26171..45903)	None
+genomic             		AH005839.2	AAB97833.1
+genomic             		AH006100.2	AAC15742.1
+genomic             		CH471139.2	EAW69538.1
+				EAW69539
+				EAW69540
+genomic             		CP068259.2(1174325..1196989)	None
+mRNA                		AB209553.1	BAD92790.1
+mRNA                		AF035625.1	AAC39527.1
+mRNA                		AF217978.1	AAG17221.1
+mRNA                		AJ844634.2	CAH59749.2
+mRNA                		AK128518.1	None
+mRNA                		AK314858.1	BAG37374.1
+mRNA                		BC007981.2	AAH07981.1
+mRNA                		BC019334.1	AAH19334.1
+mRNA                		BM993274.1	None
+mRNA                		BQ222023.1	None
+mRNA                		BU174122.1	None
+mRNA                		BU739451.1	None
+mRNA                		EF644172.1	ABR45718.1
+mRNA                		GU573916.1	ADD71158.1
+mRNA                		KU178339.1	ALQ33797.1
+mRNA                		KU178340.1	ALQ33798.1
+mRNA                		U63333.1	AAB05809.1
+
+Protein Accession		Links
+-------------------------------------------------------------------------------------------------
+Q15831.1       	GenPept(/protein/3024670)		UniProtKB/Swiss-Prot:Q15831
+
+GENE LINKOUT
+-------------------------------------------------------------------------------------------------
+The following LinkOut(www.ncbi.nlm.nih.gov/projects/linkout/index.html) resources
+are supplied by external providers. These providers are responsible for
+maintaining the links.
+
+Chemical Information
+  (Free resource) (free) Interologous Interaction Database
+	Interologous Interaction Database
+  (Order form) MilliporeSigma
+	Stk11 productsStk11 products
+  (Order form) Novus Biologicals
+	Peptides and ProteinsPeptides and ProteinsLysatesLysatesPrimary AntibodiesPrimary Antibodies
+
+Medical
+  (Free resource) (free) MedlinePlus Health Information
+	STK11 geneSTK11 gene
+
+Molecular Biology Databases
+  (Free resource) (free) Bgee database
+	STK11 gene expressionSTK11 gene expression
+  (Free resource) (free) BioGPS
+	BioGPS
+  (Free resource) (free) BioGRID Open Repository of CRISPR Screens (ORCS)
+	BioGRID CRISPR Screen Phenotypes (153 hits/1229 screens)BioGRID CRISPR Screen Phenotypes (153 hits/1229 screens)
+  (Free resource) (free) CREB Target Gene Database
+	CREB Target Gene Database
+  (Free resource) (Free registration required) (free) Creative Biogene
+	serine/threonine kinase 11serine/threonine kinase 11
+  (Free resource) (free) Eukaryotic Promoter Database
+	STK11_1STK11_1
+  (Free resource) (free) GenAge Database of Aging Related Genes
+	GenAge Database of Aging Related Genes
+  (Order form) GenScript latest version of gene cDNA ORF Clone
+	GenScript latest version of gene cDNA ORF Clone
+  (Free resource) (free) GeneNetwork
+	Records for gene expression in HumanRecords for gene expression in Human
+  (Free resource) (free) Genevisible
+	STK11STK11
+  (Free resource) (free) GlyGen glycoinformatics resource
+	GlyGen glycoinformatics resource
+  (Free resource) (free) Guide to Pharmacology
+	serine/threonine kinase 11 geneserine/threonine kinase 11 gene
+  (Free resource) (Free registration required) (free) Human Gene Mutation Database
+	Human Gene Mutation Database
+  (Free resource) (free) Human eFP Browser
+	Human eFP BrowserHuman eFP BrowserHuman eFP Browser
+  Ingenuity Pathways Analysis
+	Ingenuity Pathways Analysis
+  (Free resource) (free) InnateDB
+	InnateDB
+  (Free resource) (free) InterMine
+	InterMine
+  (Free resource) (free) Kyoto Encyclopedia of Genes and Genomes
+	Kyoto Encyclopedia of Genes and Genomes
+  (Free resource) (free) Monarch Initiative
+	Monarch InitiativeMonarch Initiative
+  (Free resource) (free) OMA Browser: Orthologous MAtrix
+	OMA Browser: Orthologous MAtrixOMA Browser: Orthologous MAtrix
+  (Free resource) (free) OrthoDB catalog of orthologs
+	OrthologsOrthologs
+  (Free resource) (free) Pharmacogenomics Knowledge Base
+	Annotated Pharmacogenomic Information for STK11 [PharmGKB]Annotated Pharmacogenomic Information for STK11 [PharmGKB]
+  (Free resource) (free) PhosphoSitePlus
+	PhosphoSitePlus® - comprehensive post-translational modification resourcePhosphoSitePlus® - comprehensive post-translational modification resource
+  (Free resource) (free) Protein Ontology Consortium
+	Protein Ontology Consortium
+  (Free resource) (free) The Gene Wiki
+	The Gene Wiki
+  (Free resource) (free) The Weizmann Institute of Science GeneCards and MalaCards databases
+	GeneCard for STK11GeneCard for STK11
+  (Free resource) (free) Vertebrate Genome Annotation (VEGA) database
+	Vertebrate Genome Annotation (VEGA) database
+  (Free resource) (free) iRefWeb - iRefIndex release 9.0 - Consolidated Interactome
+	iRefWeb - iRefIndex release 9.0 - Consolidated Interactome
+
+Research Materials
+  (Order form) Addgene Non-profit plasmid repository
+	Get Plasmids - AddgeneGet Plasmids - Addgene
+  ExactAntigen/Labome
+	reagent reviewreagent reviewreagentsreagents
+  (Order form) GeneCopoeia Inc.
+	Order miRNA target clonesOrder miRNA target clonesOrder shRNA clonesOrder shRNA clonesOrder full-length ORF cloneOrder full-length ORF clone
+  (Order form) GeneTex Inc
+	Find Recombinant Proteins and PeptidesFind Recombinant Proteins and PeptidesFind Quality AntibodiesFind Quality Antibodies
+  (Order form) Kazusa DNA Research Institute
+	Kazusa DNA Research Institute
+  LifeSpan BioSciences, Inc.
+	LSBio STK11 / LKB1 ProteinsLSBio STK11 / LKB1 Proteins
+  (Order form) NITE Biological Resource Center
+	Human cDNA clones used in NEDO Project / AK314858Human cDNA clones used in NEDO Project / AK314858Human cDNA clones used in NEDO Project / AK128518Human cDNA clones used in NEDO Project / AK128518
+  (Order form) Sino Biological Inc.
+	Human STK11 / LKB1 Gene cDNA Clone (full-length ORF Clone)Human STK11 / LKB1 Gene cDNA Clone (full-length ORF Clone)
+
+Tools
+  (Free resource) (free) GeneMANIA
+	GeneMANIA
\ No newline at end of file