Downloads: 1
Diff of
/gait-in-neurodegenerative-disease-database-1.0.0/TEST.shtml
[000000]
..
[27185e]
Switch to side-by-side view
--- a +++ b/gait-in-neurodegenerative-disease-database-1.0.0/TEST.shtml @@ -0,0 +1,208 @@ +<!DOCTYPE html> +<html> +<head> +<meta charset=utf-8> + +<title>Gait Dynamics in Neuro-Degenerative Disease Data Base</title> +<link rel="stylesheet" href="https://s3.amazonaws.com/physionet-pds/css/shop-item.css" type="text/css" media="print"> +<link rel="stylesheet" href="https://s3.amazonaws.com/physionet-pds/css/bootstrap.min.css" type="text/css" media="print"> + +<link rel="stylesheet" href="https://physionet.org/pn/print.css" type="text/css" media="print"> +<link rel="stylesheet" href="https://physionet.org/pn/css/physionet.css" media="all"><style type="text/css"> +#toc, #doi { margin-right: 1em; }#toc, #doi { background: #ecf3ff; border: solid 2px #222 } +.sf-menu > li > a { background: #dfe9ff; } +h1, h2, h3 { color: #222; background: #dfe9ff }</style> +<!-- scripts from Rich Callogero, May 2016 --> + +<script src="https://s3.amazonaws.com/physionet-pds/js/bootstrap.min.js"></script> +<script src="https://s3.amazonaws.com/physionet-pds/js/list.js"></script> + +<script src="https://physionet.org/pn/js/jquery-1.11.3.min.js"></script> +<script src="https://physionet.org/pn/js/hoverIntent.js"></script> +<script src="https://physionet.org/pn/js/superfish.min.js"></script> +<!--<script src="https://physionet.org/pn/js/debug.js"></script>--> +<script src="https://physionet.org/pn/js/accessible-superfish.js"></script> +<script src="https://physionet.org/pn/js/physionet.js"></script> +<!-- --> +<script type="text/javascript" src="https://physionet.org/pn/js/jquery.tableofcontents.min.js"></script> +<script type="text/javascript"> + var loc = window.location.pathname; + var dir = loc.substring(0, loc.lastIndexOf('/')); + dir = dir + '/'; + dir = dir.slice(15, dir.length); + var S3BL_IGNORE_PATH = true; + var BUCKET_URL = 'https://physionet-pds.s3.amazonaws.com'; + //var BUCKET_URL = 'https://s3.amazonaws.com/'; + var S3B_ROOT_DIR = dir; //'PhysioBank/apnea-ecg/'; + $(function(){ + //$("#NavBar").load("/physionet-pds/PhysioBank/NavBar.html"); + //$("#Footer").load("/physionet-pds/PhysioBank/Footer.html"); + }); +</script> + +<script type="text/javascript"> + $(document).ready(function(){ + $('ul.sf-menu').superfish({ autoArrows: false }); + if ($('h2').length) { + $('#tocwrapper').append('<ul id="toc"></ul>'); + $('#toc').tableOfContents(null, { startLevel: 2 }); + }}); +</script> +<!--#if expr="$MATHCONFIG"--> +<!-- <script type="text/javascript" src="/pn4/js/mathjax/MathJax.js?config=< ! - -#echo var="MATHCONFIG" - - >"></script>--> +<!--#endif--> +</head> + +<body> + + <header class="banner"> + <a class="hide" href="#content">Skip to content</a> + <div style="width: 100%; position: absolute; top: 0; z-index: 1; background-color: #222; min-width: 700px; padding: 0;"> + <div class="topmenu" style="float: left; padding: 0.5em 2em 0.5em 0.5em;"> + <!-- <ul class="sf-menu sf-shadow sf-arrows" >--><!--< ! - - #include virtual="https://physionet.org/pn/menu.shtml" - - > --> + <!-- </ul>--> + </div> <div style="float: left; padding: 0.6em 0 0 10em; margin: 0;"> + <a style="color:#9d9d9d;" href="/physionet-pds/index.html"><span class="glyphicon glyphicon-home"> Home</span></a> + </div> + <div style="float: right; padding: 0.6em 10em 0 0; margin: 0;"> + <a style="color:#9d9d9d;" href="https://Physionet.org"><span class="glyphicon glyphicon-transfer"> Our Website</span></a> + </div> + + + <div class="pbanner"><!-- pbanner is set to display: none --> + from <b>PhysioNet</b>, the research resource for complex physiologic signals + </div> + <div style="width: 100%; min-width: 700px; margin: 0 0 2.7em 0; background-color: transparent; padding: 0;"> + <!-- provides space above h1 header, so it isn't hidden by banner --> + <div id="top"><!-- need nested div to link to top lands in right place --></div> + </div> + + </header> + + <main><h1 style="margin-top: 1.75em; padding-top: .4em;">Gait Dynamics in Neuro-Degenerative Disease Data Base</h1><nav id="tocwrapper" style="padding: 1.5em 0 0 0; float: right;"> <!-- id to position toc added by KP, 6 July 2015 --> + </nav> + <!--#include virtual="https://physionet.org/cgi-bin/doicheck?uri=${REQUEST_URI}&title=$TITLE"--> + <a id="content" ></a> + <article id="page"><!-- added by KP, 12 June 2015 --> + + +<p> +Neuro-degenerative disease often affects gait and mobility. To understand +better the pathophysiology of these diseases and to improve our ability to +measure responses to therapeutic interventions, it may be helpful to +quantify gait dynamics accurately. The records in this database are from +patients with <a href="http://www.parkinson.org/" target="other">Parkinson's +disease</a> (n = 15), <a href="http://www.hdfoundation.org/" +target="other">Huntington's disease</a> (n = 20), or <a +href="http://www.alsa.org/" target="other">amyotrophic lateral sclerosis</a> (n += 13). Records from 16 healthy control subjects are also included here.</p> + +<p> +The raw data were obtained using force-sensitive resistors, with the +output roughly proportional to the force under the foot. +Stride-to-stride measures of footfall contact times were derived from these +signals, as illustrated below. (Click <a href="example-ts.ps">here</a> for a +PostScript version of this figure.)</p> + +<div class="outer2"><div class="inner2"> +<img src=example-ts.png alt="[Examples of Gait Time Series]" width="505"> +</div></div> + +<p> +Each of the 64 records is identified by the name of the subject group +(<tt>hunt</tt>, <tt>park</tt>, <tt>als</tt>, or <tt>control</tt>) followed by +an arbitrary ID number. The four files associated with each record have names +beginning with the record name, and suffixes indicating the type and contents +of the file:</p> + +<div class="edbtable"> +<table> <tr><th>Suffix</th><th>Contents</th></tr> +<tr><td><tt>.hea</tt></td> + <td><a href="https://physionet.org/physiotools/dbag/header-5.htm">Header</a> (text)</td></tr> +<tr><td><tt>.let</tt></td><td>Left foot signal (binary)</td></tr> +<tr><td><tt>.rit</tt></td><td>Right foot signal (binary)</td></tr> +<tr><td><tt>.ts</tt></td><td>Derived time series (text)</td></tr> +</table> +</div> + +<p>Within the time series (<tt>.ts</tt>) files, the contents are:</p> + +<div class="edbtable"> +<table> +<tr><th>Column</th><th>Contents</th></tr> +<tr><td>1</td><td>Elapsed Time (sec)</td></tr> +<tr><td>2</td><td>Left Stride Interval (sec)</td></tr> +<tr><td>3</td><td>Right Stride Interval (sec)</td></tr> +<tr><td>4</td><td>Left Swing Interval (sec)</td></tr> +<tr><td>5</td><td>Right Swing Interval (sec)</td></tr> +<tr><td>6</td><td>Left Swing Interval (% of stride)</td></tr> +<tr><td>7</td><td>Right Swing Interval (% of stride)</td></tr> +<tr><td>8</td><td>Left Stance Interval (sec)</td></tr> +<tr><td>9</td><td>Right Stance Interval (sec)</td></tr> +<tr><td>10</td><td>Left Stance Interval (% of stride)</td></tr> +<tr><td>11</td><td>Right Stance Interval (% of stride)</td></tr> +<tr><td>12</td><td>Double Support Interval (sec)</td></tr> +<tr><td>13</td><td>Double Support Interval (% of stride)</td></tr> +</table> +</div> + +<p>Please note that these time series have not been filtered.</p> + +<p> +A separate file (<a +href="subject-description.txt"><tt>subject-description.txt</tt></a>, a +tab-delimited text file) includes clinical information for each +subject, including age, gender, height, weight, walking speed, and a +measure of disease severity or duration. For the subjects with +Parkinson's disease, this is the Hohn and Yahr score (a higher score +indicates more advanced disease). For the subjects with Huntington's +disease, this is the total functional capacity measure (a lower score +indicates more advanced functional impairment). For the subjects with +amyotrophic lateral sclerosis, the number here is the time in months since the +diagnosis of the disease. For the control subjects, an arbitrary 0 is +used as a place holder.</p> + +<h3>Questions for study</h3> + +<p> +We have done some initial analyses of these data sets. Much, however, is still +unknown. For example: Are the dynamics of the sub-phases of the stride (e.g., +stance and swing) identical to that of the stride itself? What is the effect of +disease on gait asymmetry? Are stride dynamics nonlinear? Does this change +with disease?</p> + +<h3>References</h3> + +<p> +We have reported the association between disease and the dynamics of the stride +time. For more information about our analyses of these data files, please see:</p> + +<ul> +<li> Hausdorff JM, Lertratanakul A, Cudkowicz ME, Peterson AL, Kaliton D, + Goldberger AL. + <a href="http://jap.physiology.org/cgi/content/full/88/6/2045?ijkey=WKwCeA4NUn0rE&keytype=ref&siteid=physiology" + target="other">Dynamic markers of altered gait rhythm in amyotrophic + lateral sclerosis.</a> +<!-- + <a href="http://jap.physiology.org/cgi/content/full/88/6/2045" + target="other">Dynamic markers of altered gait rhythm in amyotrophic + lateral sclerosis.</a> +--> + <i>J Applied Physiology</i>; <b>88</b>:2045-2053, 2000.</li> +<li> Hausdorff JM, Mitchell SL, Firtion R, Peng CK, Cudkowicz ME, Wei JY, + Goldberger AL. + <a href="http://jap.physiology.org/cgi/content/full/82/1/262" + target="other">Altered fractal dynamics of gait: reduced stride-interval + correlations with aging and Huntington's disease.</a> + <i>J Applied Physiology</i>; <b>82</b>:262-269, 1997.</li> +</ul> + +<p>Address for correspondence: <a +href="mailto:jhausdor@caregroup.harvard.edu">jhausdor@caregroup.harvard.edu</a></p> +<div class="row"> + <div class="col-md-2"></div> + <div class="col-md-8"> + <div id="listing"></div> + </div> + <div class="col-md-2"></div> + </div> \ No newline at end of file