Downloads: 1
Diff of
/effect-of-deep-brain-stimulation-on-parkinsonian-tremor-1.0.0/README
[000000]
..
[51072c]
Switch to unified view
| a | b/effect-of-deep-brain-stimulation-on-parkinsonian-tremor-1.0.0/README | ||
|---|---|---|---|
| 1 | %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% |
||
| 2 | % |
||
| 3 | % README : contribution to PhysioBank |
||
| 4 | % of PhysioNet: www.physionet.org |
||
| 5 | % |
||
| 6 | %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% |
||
| 7 | |||
| 8 | ---------------------------------------------------- |
||
| 9 | Name of database: |
||
| 10 | ---------------------------------------------------- |
||
| 11 | DBSPDTREMOR |
||
| 12 | Effect of Deep Brain Stimulation on Parkinsonian Tremor |
||
| 13 | |||
| 14 | ---------------------------------------------------- |
||
| 15 | Name of creator(s) of database: |
||
| 16 | ---------------------------------------------------- |
||
| 17 | Anne Beuter |
||
| 18 | Michele S. Titcombe |
||
| 19 | Leon Glass |
||
| 20 | |||
| 21 | ---------------------------------------------------- |
||
| 22 | Description of database: |
||
| 23 | ---------------------------------------------------- |
||
| 24 | |||
| 25 | This database contains recordings of rest tremor velocity in the index |
||
| 26 | finger of 16 subjects with Parkinson's disease (PD) who receive chronic |
||
| 27 | high frequency electrical deep brain stimulation (DBS) either uni- or |
||
| 28 | bi-laterally within one of three targets: the ventro-intermediate |
||
| 29 | nucleus of the thalamus (Vim) (n=3), the internal Globus pallidus (GPi) |
||
| 30 | (n=7) or the subthalamic nucleus (STN) (n=8). All participants were |
||
| 31 | clinically stable at the time of the recordings, they did not show |
||
| 32 | cognitive impairment, and did not suffer from a major depressive |
||
| 33 | disorder. |
||
| 34 | |||
| 35 | The surgical procedure for high frequency deep brain stimulation |
||
| 36 | involves implanting an electrode into subcortical structures (Vim, GPi |
||
| 37 | or STN) for long-term stimulation at frequencies greater than 100 Hz. |
||
| 38 | The mechanism by which high frequency DBS suppresses tremor and reduces |
||
| 39 | other symptoms in PD is unknown. |
||
| 40 | |||
| 41 | The raw data were obtained using a low intensity velocity-transducing |
||
| 42 | laser that was directed at a piece of reflective paper on the subject's |
||
| 43 | index finger tip, with the output voltage proportional to the velocity of |
||
| 44 | the finger. Tremor was recorded for approximately 60 seconds under various |
||
| 45 | conditions: |
||
| 46 | (1) two conditions of DBS (on-off) and two conditions of medication |
||
| 47 | (L-dopa on-off) |
||
| 48 | [total: 54 recordings of approx 60 seconds each] |
||
| 49 | (2) every 15 minutes when DBS was stopped for 60 minutes (medication off) |
||
| 50 | [total: 46 recordings of approx 60 seconds each] |
||
| 51 | Please note that not all subjects were tested under all conditions. |
||
| 52 | |||
| 53 | ---------------------------------------------------- |
||
| 54 | References to any published works that describe or |
||
| 55 | make use of the database, in the form in which these |
||
| 56 | works should be cited in any future publications |
||
| 57 | ---------------------------------------------------- |
||
| 58 | |||
| 59 | Beuter, A., Titcombe, M.S., Richer, F., Gross, C., Guehl, D., |
||
| 60 | 2001. Effect of deep brain stimulation on amplitude and frequency |
||
| 61 | characteristics of rest tremor in Parkinson's disease. Thalamus & |
||
| 62 | Related Systems, Volume 1 (3): 203-211 (published by Elsevier Science). |
||
| 63 | |||
| 64 | ---------------------------------------------------- |
||
| 65 | Contact information: |
||
| 66 | ---------------------------------------------------- |
||
| 67 | (1) Dr. Anne Beuter |
||
| 68 | Faculte des Sciences du Sport et de l'Education Physique |
||
| 69 | Universite Montpellier I |
||
| 70 | 700, avenue du Pic Saint-Loup |
||
| 71 | F-34090 Montpellier, France |
||
| 72 | a.beuter@staps.univ-montp1.fr |
||
| 73 | (2) Dr. Michele Titcombe |
||
| 74 | Centre for Nonlinear Dynamics in Physiology and Medicine |
||
| 75 | McGill University |
||
| 76 | 3655, promenade Sir William Osler |
||
| 77 | Montreal, QC, Canada |
||
| 78 | titcombe@cnd.mcgill.ca |
||
| 79 | (3) Dr. Leon Glass |
||
| 80 | Centre for Nonlinear Dynamics in Physiology and Medicine |
||
| 81 | McGill University |
||
| 82 | 3655, promenade Sir William Osler |
||
| 83 | Montreal, QC, Canada |
||
| 84 | glass@cnd.mcgill.ca |
||
| 85 |